Pharmaceutical Quality (Industry)
1.0.0-ballot - ballot
Pharmaceutical Quality (Industry)
1.0.0-ballot - ballot
This page is part of the Pharmaceutical Quality (Industry) (v1.0.0-ballot: STU1 Ballot 1) based on FHIR (HL7® FHIR® Standard) v5.0.0. . For a full list of available versions, see the Directory of published versions
<Bundle xmlns="http://hl7.org/fhir">
<!-- Product Process Validation - Biologic -->
<id value="bundle-product-process-validation-pq-ex3-prod-bio"/>
<meta>
<profile
value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-product-process-validation-pq"/>
</meta>
<type value="collection"/>
<entry>
<fullUrl value="urn:uuid:2038e4c7-22b8-4c56-2d28-6c077648763f"/>
<resource>
<PlanDefinition>
<!-- id value="validationProtocol"/ -->
<id value="plandefinition-drug-pq-ex1-validation-protocol"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: PlanDefinition</b><a name="plandefinition-drug-pq-ex1-validation-protocol"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource PlanDefinition "plandefinition-drug-pq-ex1-validation-protocol" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</code></p><p><b>title</b>: DP PROCESS VALIDATION</p><p><b>type</b>: Workflow Definition <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-plan-definition-type.html">PlanDefinitionType</a>#workflow-definition; <a href="CodeSystem-cs-planType-local-pq.html">CodeSystem - Plan Type</a>#process-validation "Process Validation")</span></p><p><b>status</b>: active</p><p><b>subject</b>: <a href="#MedicinalProductDefinition_a0694a7a-aafa-4cbe-8135-c788a9a4d3d5">See above (MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5)</a></p><p><b>description</b>: Pre-defined validation acceptance criteria were established based on manufacturing development data derived from process characterization studies...</p><blockquote><p><b>action</b></p><p><b>title</b>: Formulation Buffer Preparation Process Parameter Step</p><p><b>code</b>: Formulation Buffer Preparation Process Parameter Step <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#FormulationBufferPreparationProcessParameterStep)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: Formulation Buffer Preparation Process Parameter Step</p><p><b>code</b>: FormulationBufferPreparationProcessParameterStep <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Formulation Buffer Preparation Performance Indicator Results</p><p><b>code</b>: Formulation Buffer Preparation Performance Indicator Results <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#FormulationBufferPreparationPerformanceIndicatorStep)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Thawing and Formulation Process Parameter Results</p><p><b>code</b>: Thawing and Formulation Process Parameter Resultss <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#ThawingandFormulationProcessParameterResultsStep)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Thawing and Formulation Performance Indicator Results</p><p><b>code</b>: Thawing and Formulation Performance Indicator Results <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#ThawingandFormulationPerformanceIndicatorResultsStep)</span></p><blockquote><p><b>action</b></p><p><b>title</b>: ???</p><p><b>code</b>: ??? <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote><blockquote><p><b>action</b></p></blockquote></blockquote></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Bioburden Reduction Filtration Process Parameter Results</p><p><b>code</b>: Bioburden Reduction Filtration Process Parameter Results <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#BioburdenReductionFiltrationProcessParameterResultsStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Bioburden Reduction Filtration Performance Indicator Results</p><p><b>code</b>: Bioburden Reduction Filtration Performance Indicator Results <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#BioburdenReductionFiltrationPerformanceIndicatorResultsStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434</code></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Media Challenge Hold Times</p><p><b>code</b>: Media Challenge Hold Times <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#MediaChallengeHoldTimesStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Media Challenge Results</p><p><b>code</b>: Media Challenge Results <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#MediaChallengeResultsStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524</code></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Filtered Formulated Drug Product Performance Indicator Results</p><p><b>code</b>: Filtered Formulated Drug Product Performance Indicator Results <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#FilteredFormulatedDrugProductPerformanceIndicatorResultsStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424</code></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424</code></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Fill Weight Summary</p><p><b>code</b>: Fill Weight Summary <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#FillWeightSummaryStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Filling Homogeneity Quality Attributes</p><p><b>code</b>: Filling Homogeneity Quality Attributes <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#FillingHomogeneityQualityAttributesStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Filling Results Summary</p><p><b>code</b>: Filling Results Summary <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#FillingResultsSummaryStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524</code></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Statistical Evaluation of Homogeneity Data</p><p><b>code</b>: Statistical Evaluation of Homogeneity Data <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#StatisticalEvaluationOfHomogeneityDataStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534</code></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Consistency of the Lyophilization Process</p><p><b>code</b>: Consistency of the Lyophilization Process <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#ConsistencyoftheLyophilizationProcessStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72</code></td></tr><tr><td style="display: none">*</td><td>Definition <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ActivityDefinition/b664977d-799d-a1ce-928a-6def2a9955bd</code></td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: Lyophilization Homogeneity</p><p><b>code</b>: Lyophilization Homogeneity Results <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-manufacturingStep-local-pq.html">CodeSystem - Manufacturing Step</a>#LyophilizationHomogeneityStep)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424</code></td></tr><tr><td style="display: none">*</td><td>Test <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td><td><code>ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424</code></td></tr></table></blockquote></div>
</text>
<!-- <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"/>
</meta> -->
<!-- http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f -->
<url
value="http://example-server.com/fhir/PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f"/>
<title value="DP PROCESS VALIDATION"/>
<type>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
<code value="workflow-definition"/>
<display value="Workflow Definition"/>
</coding>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-planType-local-pq"/>
<code value="process-validation"/>
<display value="Process Validation"/>
</coding>
</type>
<status value="active"/>
<subjectReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</subjectReference>
<description
value="Pre-defined validation acceptance criteria were established based on manufacturing development data derived from process characterization studies..."/>
<action>
<title
value="Formulation Buffer Preparation Process Parameter Step"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="FormulationBufferPreparationProcessParameterStep"/>
<display
value="Formulation Buffer Preparation Process Parameter Step"/>
</coding>
<text
value="Formulation Buffer Preparation Process Parameter Step"/>
</code>
<action>
<!-- this level is not really needed here, could remove. But in the case where there are different timings, it is needed, so it is here for consistency -->
<title
value="Formulation Buffer Preparation Process Parameter Step"/>
<code>
<text value="FormulationBufferPreparationProcessParameterStep"/>
</code>
<action>
<code>
<text value="Conclusion"/>
</code>
<!-- ObservationDefinition/conclusion -->
<definitionCanonical
value="ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/bufferVesselMixingSpeed -->
<definitionCanonical
value="ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/bufferVesselMixingTime -->
<definitionCanonical
value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
</action>
</action>
</action>
<action>
<title
value="Formulation Buffer Preparation Performance Indicator Results"/>
<!-- text value="Overall set of actions"/ -->
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code
value="FormulationBufferPreparationPerformanceIndicatorStep"/>
<display
value="Formulation Buffer Preparation Performance Indicator Results"/>
</coding>
</code>
<action>
<title value="???"/>
<code>
<text value="???"/>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/FBPPIpH -->
<definitionCanonical
value="ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/Osmolality -->
<definitionCanonical
value="ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/Conductivity -->
<definitionCanonical
value="ObservationDefinition/64515a3c-5134-448a-9c19-939ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/Bioburden -->
<definitionCanonical
value="ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/BacterialEndotoxins -->
<definitionCanonical
value="ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958424"/>
</action>
</action>
</action>
<action>
<title value="Thawing and Formulation Process Parameter Results"/>
<!-- text value="Overall set of actions"/ -->
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="ThawingandFormulationProcessParameterResultsStep"/>
<display
value="Thawing and Formulation Process Parameter Resultss"/>
</coding>
</code>
<action>
<title value="???"/>
<code>
<text value="???"/>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/ThawingTemp -->
<definitionCanonical
value="ObservationDefinition/74515a3c-5034-448a-9c19-938ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/ThawingTime -->
<definitionCanonical
value="ObservationDefinition/fc27b5d6-9fe2-91c2-2d16-47cb5b295e72"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/formulationVesselMixingSpeed -->
<definitionCanonical
value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/formulationVesselMixingTime -->
<definitionCanonical
value="ObservationDefinition/fc27b5d5-9fe1-92c2-2d06-47cb5b295e73"/>
</action>
</action>
</action>
<action>
<title
value="Thawing and Formulation Performance Indicator Results"/>
<!-- text value="Overall set of actions"/ -->
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code
value="ThawingandFormulationPerformanceIndicatorResultsStep"/>
<display
value="Thawing and Formulation Performance Indicator Results"/>
</coding>
</code>
<action>
<title value="???"/>
<code>
<text value="???"/>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/ThawingFBPPIpH -->
<definitionCanonical
value="ObservationDefinition/fc27b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/ThawingOsmolality -->
<definitionCanonical
value="ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/ThawingConductivity -->
<definitionCanonical
value="ObservationDefinition/74515a3c-5134-448a-9c19-939ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/ThawingBacterialEndotoxins -->
<definitionCanonical
value="ObservationDefinition/64515b4c-5134-448a-9c19-949ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/Polysorbate -->
<definitionCanonical
value="ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958434"/>
</action>
</action>
</action>
<action>
<title
value="Bioburden Reduction Filtration Process Parameter Results"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code
value="BioburdenReductionFiltrationProcessParameterResultsStep"/>
<display
value="Bioburden Reduction Filtration Process Parameter Results"/>
</coding>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/FiltrationPressure -->
<definitionCanonical
value="ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434"/>
</action>
</action>
<action>
<title
value="Bioburden Reduction Filtration Performance Indicator Results"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code
value="BioburdenReductionFiltrationPerformanceIndicatorResultsStep"/>
<display
value="Bioburden Reduction Filtration Performance Indicator Results"/>
</coding>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/PreFiltrationBioburden -->
<definitionCanonical
value="ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/PostFiltrationFilterIntegrity -->
<definitionCanonical
value="ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434"/>
</action>
</action>
<action>
<title value="Media Challenge Hold Times"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="MediaChallengeHoldTimesStep"/>
<display value="Media Challenge Hold Times"/>
</coding>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/MediaHoldTime -->
<definitionCanonical
value="ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434"/>
</action>
</action>
<action>
<title value="Media Challenge Results"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="MediaChallengeResultsStep"/>
<display value="Media Challenge Results"/>
</coding>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/MediaBioburden -->
<definitionCanonical
value="ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/GrowthPromotion -->
<definitionCanonical
value="ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524"/>
</action>
</action>
<action>
<title
value="Filtered Formulated Drug Product Performance Indicator Results"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code
value="FilteredFormulatedDrugProductPerformanceIndicatorResultsStep"/>
<display
value="Filtered Formulated Drug Product Performance Indicator Results"/>
</coding>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/SE-UHPLCMainPeak -->
<definitionCanonical
value="ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/SE-UHPLCMainPeakGraph -->
<definitionCanonical
value="ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/SE-UHPLCHMW -->
<definitionCanonical
value="ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424"/>
</action>
</action>
<action>
<title value="Fill Weight Summary"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="FillWeightSummaryStep"/>
<display value="Fill Weight Summary"/>
</coding>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/FillWeight -->
<definitionCanonical
value="ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524"/>
</action>
</action>
<!-- no tests just a conclusion -->
<action>
<title value="Filling Homogeneity Quality Attributes"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="FillingHomogeneityQualityAttributesStep"/>
<display value="Filling Homogeneity Quality Attributes"/>
</coding>
<text value="Filling Homogeneity Quality Attributes"/>
</code>
<action>
<code>
<text value="Conclusion"/>
</code>
<!-- ObservationDefinition/conclusionHomogeneity -->
<definitionCanonical
value="ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424"/>
</action>
</action>
<action>
<title value="Filling Results Summary"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="FillingResultsSummaryStep"/>
<display value="Filling Results Summary"/>
</coding>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/ProteinConcentration -->
<definitionCanonical
value="ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/Polysorbate80Concentration -->
<definitionCanonical
value="ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524"/>
</action>
</action>
<action>
<title value="Statistical Evaluation of Homogeneity Data"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="StatisticalEvaluationOfHomogeneityDataStep"/>
<display value="Statistical Evaluation of Homogeneity Data"/>
</coding>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/ProteinConcentrationStats -->
<definitionCanonical
value="ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534"/>
</action>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/Polysorbate80Concentration -->
<definitionCanonical
value="ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524"/>
</action>
</action>
<action>
<title value="Consistency of the Lyophilization Process"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="ConsistencyoftheLyophilizationProcessStep"/>
<display value="Consistency of the Lyophilization Process"/>
</coding>
</code>
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/ResidualMoisture -->
<definitionCanonical
value="ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"/>
</action>
<action>
<code>
<text value="Definition"/>
</code>
<!-- ActivityDefinition/LyophilizationAct -->
<definitionCanonical
value="ActivityDefinition/b664977d-799d-a1ce-928a-6def2a9955bd"/>
</action>
</action>
<action>
<title value="Lyophilization Homogeneity"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-manufacturingStep-local-pq"/>
<code value="LyophilizationHomogeneityStep"/>
<display value="Lyophilization Homogeneity Results"/>
</coding>
</code>
<!-- there are 2 types of obs that correspond to this. Ones per batch, with a %, and ones that are not per batch and have a conclusion (and a number of samples) -->
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/SE-UHPLCMainPeakLyoph -->
<definitionCanonical
value="ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"/>
</action>
<!-- there are 2 types of obs that correspond to this. Ones per batch, with a %, and ones that are not per batch and have a conclusion (and a number of samples) -->
<action>
<code>
<text value="Test"/>
</code>
<!-- ObservationDefinition/SE-UHPLCHMWLyoph -->
<definitionCanonical
value="ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"/>
</action>
</action>
</PlanDefinition>
</resource>
</entry>
<!-- ActDef that acts as something a Procedure can be done for (could be contained) -->
<entry>
<fullUrl value="urn:uuid:b664977d-799d-a1ce-928a-6def2a9955bd"/>
<resource>
<ActivityDefinition>
<!-- LyophilizationAct -->
<id value="b664977d-799d-a1ce-928a-6def2a9955bd"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ActivityDefinition</b><a name="b664977d-799d-a1ce-928a-6def2a9955bd"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ActivityDefinition "b664977d-799d-a1ce-928a-6def2a9955bd" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ActivityDefinition/b664977d-799d-a1ce-928a-6def2a9955bd</code></p><p><b>title</b>: Lyophilization</p><p><b>status</b>: active</p></div>
</text>
<!-- <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/ActivityDefinition-test-drug-pq"/>
</meta> -->
<!-- http://example-server.com/fhir/ActivityDefinition/b664977d-799d-a1ce-928a-6def2a9955bd -->
<url
value="http://example-server.com/fhir/ActivityDefinition/b664977d-799d-a1ce-928a-6def2a9955bd"/>
<title value="Lyophilization"/>
<status value="active"/>
</ActivityDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b08"/>
<resource>
<Organization>
<!-- 378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<id value="378fbe5f-5926-3a5c-4c64-5428df877b08"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Organization</b><a name="378fbe5f-5926-3a5c-4c64-5428df877b08"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization "378fbe5f-5926-3a5c-4c64-5428df877b08" </p></div><p><b>name</b>: Testing Lab</p></div>
</text>
<name value="Testing Lab"/>
</Organization>
</resource>
</entry>
<!-- Diagnostic report doesn't carry much extra value but does collect all the observations -->
<entry>
<fullUrl value="urn:uuid:b664977d-799d-a1ce-928a-5def2a9955bd"/>
<resource>
<DiagnosticReport>
<!-- ideally this wants a subject, but it can only be a Medication (batch) and we have multiple.
however the observations themselves do have subjects -->
<id value="processValidationReport"/>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: DiagnosticReport</b><a name="processValidationReport"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DiagnosticReport "processValidationReport" </p></div><p><b>Triggered by</b>: <a href="Bundle-bundle-drug-substance-characterization-pq-ex1.html#PlanDefinition_2038e4c7-22b8-4c56-2d28-6c077648763f">PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f</a></p><p><b>status</b>: final</p><p><b>code</b>: Process Validation Report <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-reportType-local-pq.html">CodeSystem - Report Type</a>#Process Validation Report)</span></p><p><b>effective</b>: 2020-12</p><p><b>result</b>: </p><ul><li><a href="#Observation_9c56948a-2a39-6609-1c01-4d197ea57a33">See above (Observation/9c56948a-2a39-6609-1c01-4d197ea57a33)</a></li><li><a href="#Observation_9c56948a-3a39-6609-1c01-4d197ea57a33">See above (Observation/9c56948a-3a39-6609-1c01-4d197ea57a33)</a></li><li><a href="#Observation_9c56948a-4a39-6609-1c01-4d197ea57a33">See above (Observation/9c56948a-4a39-6609-1c01-4d197ea57a33)</a></li><li><a href="#Observation_9c56948a-2a39-6609-2c01-4d197ea57a33">See above (Observation/9c56948a-2a39-6609-2c01-4d197ea57a33)</a></li><li><a href="#Observation_9c56948a-3a39-6609-2c01-4d197ea57a33">See above (Observation/9c56948a-3a39-6609-2c01-4d197ea57a33)</a></li><li><a href="#Observation_9c56948a-4a39-6609-3c01-4d197ea57a33">See above (Observation/9c56948a-4a39-6609-3c01-4d197ea57a33)</a></li><li><a href="#Observation_44aa47fd-8964-4f96-6495-b2bec7f160e7">See above (Observation/44aa47fd-8964-4f96-6495-b2bec7f160e7)</a></li><li><a href="#Observation_54aa47fd-8964-4f96-6495-b2bec7f160e7">See above (Observation/54aa47fd-8964-4f96-6495-b2bec7f160e7)</a></li><li><a href="#Observation_54aa48fd-8964-4f96-6495-b2bec7f160e7">See above (Observation/54aa48fd-8964-4f96-6495-b2bec7f160e7)</a></li><li><a href="#Observation_44aa47fd-8964-4f96-6495-b2bec7f161e7">See above (Observation/44aa47fd-8964-4f96-6495-b2bec7f161e7)</a></li><li><a href="#Observation_54aa47fd-8964-4f96-6495-b2bec7f162e7">See above (Observation/54aa47fd-8964-4f96-6495-b2bec7f162e7)</a></li><li><a href="#Observation_54aa48fd-8964-4f96-6495-b2bec7f163e7">See above (Observation/54aa48fd-8964-4f96-6495-b2bec7f163e7)</a></li><li><a href="#Observation_44aa47fd-8964-5f96-6495-b2bec7f161e7">See above (Observation/44aa47fd-8964-5f96-6495-b2bec7f161e7)</a></li><li><a href="#Observation_44aa47fd-9964-5f96-6495-b2bec7f161e8">See above (Observation/44aa47fd-9964-5f96-6495-b2bec7f161e8)</a></li><li><a href="#Observation_44aa47fd-8964-5f96-6495-b2bec7f161e8">See above (Observation/44aa47fd-8964-5f96-6495-b2bec7f161e8)</a></li><li><a href="#Observation_44aa47fd-8964-5f96-7495-b2bec7f161e8">See above (Observation/44aa47fd-8964-5f96-7495-b2bec7f161e8)</a></li><li><a href="#Observation_44aa47fd-9964-5f97-6495-b2bec7f161e8">See above (Observation/44aa47fd-9964-5f97-6495-b2bec7f161e8)</a></li><li><a href="#Observation_44aa47fd-8964-5f98-6495-b2bec7f161e8">See above (Observation/44aa47fd-8964-5f98-6495-b2bec7f161e8)</a></li><li><a href="#Observation_44aa47fd-8964-5f99-7495-b2bec7f161e8">See above (Observation/44aa47fd-8964-5f99-7495-b2bec7f161e8)</a></li><li><a href="#Observation_54aa47fd-9964-5f97-6495-b2bec7f161e8">See above (Observation/54aa47fd-9964-5f97-6495-b2bec7f161e8)</a></li><li><a href="#Observation_64aa47fd-8964-5f98-6495-b2bec7f161e8">See above (Observation/64aa47fd-8964-5f98-6495-b2bec7f161e8)</a></li><li><a href="#Observation_74aa47fd-8964-5f99-7495-b2bec7f161e8">See above (Observation/74aa47fd-8964-5f99-7495-b2bec7f161e8)</a></li><li><a href="#Observation_44ba47fd-8964-4f96-6495-b2bec7f161e7">See above (Observation/44ba47fd-8964-4f96-6495-b2bec7f161e7)</a></li><li><a href="#Observation_54ca47fd-8964-4f96-6495-b2bec7f162e7">See above (Observation/54ca47fd-8964-4f96-6495-b2bec7f162e7)</a></li><li><a href="#Observation_54da48fd-8964-4f96-6495-b2bec7f163e7">See above (Observation/54da48fd-8964-4f96-6495-b2bec7f163e7)</a></li><li><a href="#Observation_44ba47fd-8964-5f96-6495-b2bec7f161e7">See above (Observation/44ba47fd-8964-5f96-6495-b2bec7f161e7)</a></li><li><a href="#Observation_44ba47fd-8964-4f97-6495-b2bec7f161e7">See above (Observation/44ba47fd-8964-4f97-6495-b2bec7f161e7)</a></li><li><a href="#Observation_54ca47fd-8964-4f98-6495-b2bec7f162e7">See above (Observation/54ca47fd-8964-4f98-6495-b2bec7f162e7)</a></li><li><a href="#Observation_54da48fd-8964-4f99-6495-b2bec7f163e7">See above (Observation/54da48fd-8964-4f99-6495-b2bec7f163e7)</a></li><li><a href="#Observation_55aa47fd-9964-5f97-6495-b2bec7f161e8">See above (Observation/55aa47fd-9964-5f97-6495-b2bec7f161e8)</a></li><li><a href="#Observation_45aa47fd-8964-4f96-6495-b2bec7f160f7">See above (Observation/45aa47fd-8964-4f96-6495-b2bec7f160f7)</a></li><li><a href="#Observation_54aa47fd-9964-5f97-6495-b2bec8f161e8">See above (Observation/54aa47fd-9964-5f97-6495-b2bec8f161e8)</a></li><li><a href="#Observation_54aa47fd-9964-5f97-6495-b2bec8f162e8">See above (Observation/54aa47fd-9964-5f97-6495-b2bec8f162e8)</a></li><li><a href="#Observation_54aa47fd-9965-5f97-6495-b2bec8f161e8">See above (Observation/54aa47fd-9965-5f97-6495-b2bec8f161e8)</a></li><li><a href="#Observation_44ba47fd-8964-4f96-6495-b2bec7f161e8">See above (Observation/44ba47fd-8964-4f96-6495-b2bec7f161e8)</a></li><li><a href="#Observation_44ba47fd-9964-4f96-6495-b2bec7f161e8">See above (Observation/44ba47fd-9964-4f96-6495-b2bec7f161e8)</a></li><li><a href="#Observation_44ba47fd-9964-4f96-6496-b2bec7f161e8">See above (Observation/44ba47fd-9964-4f96-6496-b2bec7f161e8)</a></li><li><a href="#Observation_54ba47fd-8964-4f96-6495-b2bec7f161e7">See above (Observation/54ba47fd-8964-4f96-6495-b2bec7f161e7)</a></li><li><a href="#Observation_54ba47fd-8964-4f96-6495-b2bec7f161e8">See above (Observation/54ba47fd-8964-4f96-6495-b2bec7f161e8)</a></li><li><a href="#Observation_54ba47fd-8964-4f96-6495-b2bec7f161e9">See above (Observation/54ba47fd-8964-4f96-6495-b2bec7f161e9)</a></li><li><a href="#Observation_54ba48fd-8964-4f96-6495-b2bec7f161e7">See above (Observation/54ba48fd-8964-4f96-6495-b2bec7f161e7)</a></li><li><a href="#Observation_54bb47fd-8964-4f96-6495-b2bec7f161e7">See above (Observation/54bb47fd-8964-4f96-6495-b2bec7f161e7)</a></li><li><a href="#Observation_54ba47fd-9964-4f96-6495-b2bec7f161e8">See above (Observation/54ba47fd-9964-4f96-6495-b2bec7f161e8)</a></li><li><a href="#Observation_54ba47fe-8964-4f96-6495-b2bec7f161e9">See above (Observation/54ba47fe-8964-4f96-6495-b2bec7f161e9)</a></li><li><a href="#Observation_64ba48fd-8964-4f96-6495-b2bec7f161e7">See above (Observation/64ba48fd-8964-4f96-6495-b2bec7f161e7)</a></li></ul><p><b>conclusion</b>: The samples have been assessed and the conclusion is...</p></div>
</text>
<extension
url="http://hl7.org/fhir/StructureDefinition/workflow-triggeredBy">
<valueReference>
<!-- PlanDefinition/plandefinition-drug-pq-ex1-validation-protocol -->
<reference
value="PlanDefinition/2038e4c7-22b8-4c56-2d28-6c077648763f"/>
</valueReference>
</extension>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-reportType-local-pq"/>
<code value="Process Validation Report"/>
<display value="Process Validation Report"/>
</coding>
</code>
<effectiveDateTime value="2020-12"/>
<result>
<!-- Observation/bufferVesselMixingSpeed1 -->
<reference
value="Observation/9c56948a-2a39-6609-1c01-4d197ea57a33"/>
</result>
<result>
<!-- Observation/bufferVesselMixingSpeed2 -->
<reference
value="Observation/9c56948a-3a39-6609-1c01-4d197ea57a33"/>
</result>
<result>
<!-- Observation/bufferVesselMixingSpeed3 -->
<reference
value="Observation/9c56948a-4a39-6609-1c01-4d197ea57a33"/>
</result>
<result>
<!-- Observation/bufferVesselMixingTime1 -->
<reference
value="Observation/9c56948a-2a39-6609-2c01-4d197ea57a33"/>
</result>
<result>
<!-- Observation/bufferVesselMixingTime2 -->
<reference
value="Observation/9c56948a-3a39-6609-2c01-4d197ea57a33"/>
</result>
<result>
<!-- Observation/bufferVesselMixingTime3 -->
<reference
value="Observation/9c56948a-4a39-6609-3c01-4d197ea57a33"/>
</result>
<result>
<!-- Observation/ph1 -->
<reference
value="Observation/44aa47fd-8964-4f96-6495-b2bec7f160e7"/>
</result>
<result>
<!-- Observation/ph2 -->
<reference
value="Observation/54aa47fd-8964-4f96-6495-b2bec7f160e7"/>
</result>
<result>
<!-- Observation/ph3 -->
<reference
value="Observation/54aa48fd-8964-4f96-6495-b2bec7f160e7"/>
</result>
<result>
<!-- Observation/osmolality1 -->
<reference
value="Observation/44aa47fd-8964-4f96-6495-b2bec7f161e7"/>
</result>
<result>
<!-- Observation/osmolality2 -->
<reference
value="Observation/54aa47fd-8964-4f96-6495-b2bec7f162e7"/>
</result>
<result>
<!-- Observation/osmolality3 -->
<reference
value="Observation/54aa48fd-8964-4f96-6495-b2bec7f163e7"/>
</result>
<result>
<!-- Observation/postFiltrationFilterIntegrity1 -->
<reference
value="Observation/44aa47fd-8964-5f96-6495-b2bec7f161e7"/>
</result>
<result>
<!-- Observation/mediaChallengeHoldTimesStep1 -->
<reference
value="Observation/44aa47fd-9964-5f96-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/mediaChallengeHoldTimesStep2 -->
<reference
value="Observation/44aa47fd-8964-5f96-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/mediaChallengeHoldTimesStep3 -->
<reference
value="Observation/44aa47fd-8964-5f96-7495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/mediaChallengeBioburden1 -->
<reference
value="Observation/44aa47fd-9964-5f97-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/mediaChallengeBioburden2 -->
<reference
value="Observation/44aa47fd-8964-5f98-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/mediaChallengeBioburden3 -->
<reference
value="Observation/44aa47fd-8964-5f99-7495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/growthPromotion1 -->
<reference
value="Observation/54aa47fd-9964-5f97-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/growthPromotion2 -->
<reference
value="Observation/64aa47fd-8964-5f98-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/growthPromotion3 -->
<reference
value="Observation/74aa47fd-8964-5f99-7495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/SE-UHPLCMainPeak1 -->
<reference
value="Observation/44ba47fd-8964-4f96-6495-b2bec7f161e7"/>
</result>
<result>
<!-- Observation/SE-UHPLCMainPeak2 -->
<reference
value="Observation/54ca47fd-8964-4f96-6495-b2bec7f162e7"/>
</result>
<result>
<!-- Observation/SE-UHPLCMainPeak3 -->
<reference
value="Observation/54da48fd-8964-4f96-6495-b2bec7f163e7"/>
</result>
<result>
<!-- Observation/SE-UHPLCMainPeakGraph1 -->
<reference
value="Observation/44ba47fd-8964-5f96-6495-b2bec7f161e7"/>
</result>
<result>
<!-- Observation/SE-UHPLCHMW1 -->
<reference
value="Observation/44ba47fd-8964-4f97-6495-b2bec7f161e7"/>
</result>
<result>
<!-- Observation/SE-UHPLCHMW2 -->
<reference
value="Observation/54ca47fd-8964-4f98-6495-b2bec7f162e7"/>
</result>
<result>
<!-- Observation/SE-UHPLCHMW3 -->
<reference
value="Observation/54da48fd-8964-4f99-6495-b2bec7f163e7"/>
</result>
<result>
<!-- Observation/fillWeight1 -->
<reference
value="Observation/55aa47fd-9964-5f97-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/fillingHomogeneityConclusion-nosubject -->
<reference
value="Observation/45aa47fd-8964-4f96-6495-b2bec7f160f7"/>
</result>
<result>
<!-- Observation/proteinConcentration1 -->
<reference
value="Observation/54aa47fd-9964-5f97-6495-b2bec8f161e8"/>
</result>
<result>
<!-- Observation/polysorbate2 -->
<reference
value="Observation/54aa47fd-9964-5f97-6495-b2bec8f162e8"/>
</result>
<result>
<!-- Observation/proteinConcentrationStats1 -->
<reference
value="Observation/54aa47fd-9965-5f97-6495-b2bec8f161e8"/>
</result>
<result>
<!-- Observation/residualMoisture1 -->
<reference
value="Observation/44ba47fd-8964-4f96-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/residualMoisture2 -->
<reference
value="Observation/44ba47fd-9964-4f96-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/residualMoisture3 -->
<reference
value="Observation/44ba47fd-9964-4f96-6496-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/SE-UHPLCMainPeakLyoph1 -->
<reference
value="Observation/54ba47fd-8964-4f96-6495-b2bec7f161e7"/>
</result>
<result>
<!-- Observation/SE-UHPLCMainPeakLyoph2 -->
<reference
value="Observation/54ba47fd-8964-4f96-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/SE-UHPLCMainPeakLyoph3 -->
<reference
value="Observation/54ba47fd-8964-4f96-6495-b2bec7f161e9"/>
</result>
<result>
<!-- Observation/SE-UHPLCMainPeakLyophConclusionObs -->
<reference
value="Observation/54ba48fd-8964-4f96-6495-b2bec7f161e7"/>
</result>
<result>
<!-- Observation/SE-UHPLCHMWLyoph1 -->
<reference
value="Observation/54bb47fd-8964-4f96-6495-b2bec7f161e7"/>
</result>
<result>
<!-- Observation/SE-UHPLCHMWLyoph2 -->
<reference
value="Observation/54ba47fd-9964-4f96-6495-b2bec7f161e8"/>
</result>
<result>
<!-- Observation/SE-UHPLCHMWLyoph3 -->
<reference
value="Observation/54ba47fe-8964-4f96-6495-b2bec7f161e9"/>
</result>
<result>
<!-- Observation/SE-UHPLCHMWLyophConclusionObs -->
<reference
value="Observation/64ba48fd-8964-4f96-6495-b2bec7f161e7"/>
</result>
<conclusion
value="The samples have been assessed and the conclusion is..."/>
</DiagnosticReport>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
<resource>
<ObservationDefinition>
<!-- bufferVesselMixingSpeed -->
<id value="fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "fd17b5d6-9fe1-91c2-2d06-47cb5b295e72" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: Buffer vessel mixing speed (rpm)</p><p><b>status</b>: active</p><p><b>code</b>: Buffer vessel mixing speed (rpm) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Buffer vessel mixing speed (rpm))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>150-250 rpm</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
<title value="Buffer vessel mixing speed (rpm)"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Buffer vessel mixing speed (rpm)"/>
<display value="Buffer vessel mixing speed (rpm)"/>
</coding>
<text value="Buffer vessel mixing speed (rpm)"/>
</code>
<qualifiedValue>
<range>
<low>
<value value="150"/>
<unit value="rpm"/>
</low>
<high>
<value value="250"/>
<unit value="rpm"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
<resource>
<ObservationDefinition>
<!-- formulationVesselMixingSpeed -->
<id value="fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "fc17b5d5-9fe1-91c2-2d06-47cb5b295e72" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72</code></p><p><b>title</b>: Formulation vessel mixing speed (rpm)</p><p><b>status</b>: active</p><p><b>code</b>: Formulation vessel mixing speed (rpm) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Formulation vessel mixing speed (rpm))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>150-250 rpm</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e72"/>
<title value="Formulation vessel mixing speed (rpm)"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Formulation vessel mixing speed (rpm)"/>
<display value="Formulation vessel mixing speed (rpm)"/>
</coding>
<text value="Formulation vessel mixing speed (rpm)"/>
</code>
<qualifiedValue>
<range>
<low>
<value value="150"/>
<unit value="rpm"/>
</low>
<high>
<value value="250"/>
<unit value="rpm"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
<resource>
<ObservationDefinition>
<!-- bufferVesselMixingTime -->
<id value="fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "fc17b5d5-9fe1-91c2-2d06-47cb5b295e73" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73</code></p><p><b>title</b>: Buffer vessel mixing time (min)</p><p><b>status</b>: active</p><p><b>code</b>: Buffer vessel mixing time (min) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Buffer vessel mixing time (min))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>45-55 mins</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
<title value="Buffer vessel mixing time (min)"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Buffer vessel mixing time (min)"/>
<display value="Buffer vessel mixing time (min)"/>
</coding>
<text value="Buffer vessel mixing time (min)"/>
</code>
<qualifiedValue>
<range>
<low>
<value value="45"/>
<unit value="mins"/>
<system value="http://unitsofmeasure.org"/>
<code value="min"/>
</low>
<high>
<value value="55"/>
<unit value="mins"/>
<system value="http://unitsofmeasure.org"/>
<code value="min"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fc27b5d5-9fe1-92c2-2d06-47cb5b295e73"/>
<resource>
<ObservationDefinition>
<!-- formulationVesselMixingTime -->
<id value="fc27b5d5-9fe1-92c2-2d06-47cb5b295e73"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="fc27b5d5-9fe1-92c2-2d06-47cb5b295e73"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "fc27b5d5-9fe1-92c2-2d06-47cb5b295e73" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc27b5d5-9fe1-92c2-2d06-47cb5b295e73</code></p><p><b>title</b>: Formulation vessel mixing time (min)</p><p><b>status</b>: active</p><p><b>code</b>: Formulation vessel mixing time (min) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Formulation vessel mixing time (min))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>45-55 mins</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/fc27b5d5-9fe1-92c2-2d06-47cb5b295e73 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/fc27b5d5-9fe1-92c2-2d06-47cb5b295e73"/>
<title value="Formulation vessel mixing time (min)"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Formulation vessel mixing time (min)"/>
<display value="Formulation vessel mixing time (min)"/>
</coding>
<text value="Formulation vessel mixing time (min)"/>
</code>
<qualifiedValue>
<range>
<low>
<value value="45"/>
<unit value="mins"/>
<system value="http://unitsofmeasure.org"/>
<code value="min"/>
</low>
<high>
<value value="55"/>
<unit value="mins"/>
<system value="http://unitsofmeasure.org"/>
<code value="min"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"/>
<resource>
<ObservationDefinition>
<!-- ResidualMoisture -->
<id value="fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "fc27b6d6-9fe2-91c2-2d16-47cb5b295e72" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72</code></p><p><b>title</b>: Residual Moisture (%)</p><p><b>status</b>: active</p><p><b>code</b>: ResidualMoisture <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Residual Moisture "Residual Moisture")</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-7.15</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Residual Moisture - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Residual Moisture - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Residual Moisture - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Residual Moisture - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SAMP)</span></p></blockquote></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"/>
<title value="Residual Moisture (%)"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Residual Moisture"/>
<display value="Residual Moisture"/>
</coding>
<text value="ResidualMoisture"/>
</code>
<qualifiedValue>
<range>
<high>
<value value="7.15"/>
<unit value="%"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</high>
</range>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Residual Moisture - Min"/>
<display value="Residual Moisture - Min"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Residual Moisture - Max"/>
<display value="Residual Moisture - Max"/>
</coding>
</code>
</component>
<component>
<!-- are expected to have a component that says number of samples -->
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SAMP"/>
<display value="Number of Samples"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fc27b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
<resource>
<ObservationDefinition>
<!-- ThawingFBPPIpH -->
<id value="fc27b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="fc27b5d6-9fe1-91c2-2d16-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "fc27b5d6-9fe1-91c2-2d16-47cb5b295e72" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe1-91c2-2d16-47cb5b295e72</code></p><p><b>title</b>: pH</p><p><b>status</b>: active</p><p><b>code</b>: pH <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#pH)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>6.55-7.15 pH</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe1-91c2-2d16-47cb5b295e72 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
<title value="pH"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="pH"/>
<display value="pH"/>
</coding>
<text value="pH"/>
</code>
<qualifiedValue>
<range>
<low>
<value value="6.55"/>
<unit value="pH"/>
<system value="http://unitsofmeasure.org"/>
<code value="pH"/>
</low>
<high>
<value value="7.15"/>
<unit value="pH"/>
<system value="http://unitsofmeasure.org"/>
<code value="pH"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fc27b5d6-9fe2-91c2-2d16-47cb5b295e72"/>
<resource>
<ObservationDefinition>
<!-- ThawingTime -->
<id value="fc27b5d6-9fe2-91c2-2d16-47cb5b295e72"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="fc27b5d6-9fe2-91c2-2d16-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "fc27b5d6-9fe2-91c2-2d16-47cb5b295e72" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe2-91c2-2d16-47cb5b295e72</code></p><p><b>title</b>: Thaw Time</p><p><b>status</b>: active</p><p><b>code</b>: Thaw Time (hr) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Thaw Time "Thaw Time")</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-3</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe2-91c2-2d16-47cb5b295e72 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/fc27b5d6-9fe2-91c2-2d16-47cb5b295e72"/>
<title value="Thaw Time"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Thaw Time"/>
<display value="Thaw Time"/>
</coding>
<text value="Thaw Time (hr)"/>
</code>
<qualifiedValue>
<range>
<high>
<value value="3"/>
<unit value="hour"/>
<system value="http://unitsofmeasure.org"/>
<code value="h"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
<resource>
<ObservationDefinition>
<!-- FBPPIpH -->
<id value="fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "fc17b5d6-9fe1-91c2-2d16-47cb5b295e72" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72</code></p><p><b>title</b>: pH</p><p><b>status</b>: active</p><p><b>code</b>: pH <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#pH)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>6.95-7.05 pH</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
<title value="pH"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="pH"/>
<display value="pH"/>
</coding>
<text value="pH"/>
</code>
<qualifiedValue>
<range>
<low>
<value value="6.95"/>
<unit value="pH"/>
<system value="http://unitsofmeasure.org"/>
<code value="pH"/>
</low>
<high>
<value value="7.05"/>
<unit value="pH"/>
<system value="http://unitsofmeasure.org"/>
<code value="pH"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64525a3c-5034-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- Osmolality -->
<id value="64525a3c-5034-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64525a3c-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64525a3c-5034-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Osmolality</p><p><b>status</b>: active</p><p><b>code</b>: Osmolality (mOsm/kg) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Osmolality "Osmolality")</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>250-300 mOsm/kg</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424"/>
<title value="Osmolality"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Osmolality"/>
<display value="Osmolality"/>
</coding>
<text value="Osmolality (mOsm/kg)"/>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="250"/>
<unit value="mOsm/kg"/>
</low>
<!-- todo UCUM -->
<high>
<value value="300"/>
<unit value="mOsm/kg"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64525a3d-5134-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- SE-UHPLCMainPeakLyoph -->
<id value="64525a3d-5134-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64525a3d-5134-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64525a3d-5134-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC Main Peak</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td/><td>85-95 %</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLC Main Peak - Conclusion)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#OVERALLSAMP)</span></p></blockquote></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"/>
<title value="SE-UHPLC Main Peak"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<qualifiedValue>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq">
<valueString value="± 5% target"/>
</extension>
<range>
<!-- todo UCUM -->
<low>
<value value="85"/>
<unit value="%"/>
</low>
<!-- todo UCUM -->
<high>
<value value="95"/>
<unit value="%"/>
</high>
</range>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLC Main Peak - Conclusion"/>
<display value="SE-UHPLC Main Peak - Conclusion"/>
</coding>
</code>
<qualifiedValue>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
<valueString value="Pass"/>
</extension>
</qualifiedValue>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="OVERALLSAMP"/>
<display value="Number of Samples"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64525a3d-5144-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- SE-UHPLCHMWLyoph -->
<id value="64525a3d-5144-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64525a3d-5144-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64525a3d-5144-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC HMW</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC HMW (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW "SE-UHPLC HMW")</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td/><td>88-92 %</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLC HMW - Conclusion)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#OVERALLSAMP)</span></p></blockquote></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"/>
<title value="SE-UHPLC HMW"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW"/>
<display value="SE-UHPLC HMW"/>
</coding>
<text value="SE-UHPLC HMW (%)"/>
</code>
<qualifiedValue>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-display-pq">
<valueString value="± 2% target"/>
</extension>
<range>
<!-- todo UCUM -->
<low>
<value value="88"/>
<unit value="%"/>
</low>
<!-- todo UCUM -->
<high>
<value value="92"/>
<unit value="%"/>
</high>
</range>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLC HMW - Conclusion"/>
<display value="SE-UHPLC HMW - Conclusion"/>
</coding>
</code>
<qualifiedValue>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
<valueString value="Pass"/>
</extension>
</qualifiedValue>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="OVERALLSAMP"/>
<display value="Number of Samples"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64525a3d-5034-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- SE-UHPLCMainPeak -->
<id value="64525a3d-5034-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64525a3d-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64525a3d-5034-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC Main Peak</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>5-? %</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424"/>
<title value="SE-UHPLC Main Peak"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="5"/>
<unit value="%"/>
</low>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64525a4d-5034-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- SE-UHPLCMainPeakGraph -->
<id value="64525a4d-5034-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64525a4d-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64525a4d-5034-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC Main Peak Graph</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC Main Peak (graph) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424"/>
<title value="SE-UHPLC Main Peak Graph"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (graph)"/>
</code>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64525a33-5034-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- SE-UHPLCHMW -->
<id value="64525a33-5034-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64525a33-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64525a33-5034-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: SE-UHPLC HMW</p><p><b>status</b>: active</p><p><b>code</b>: SE-UHPLC HMW (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW "SE-UHPLC HMW")</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>7-? %</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424"/>
<title value="SE-UHPLC HMW"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW"/>
<display value="SE-UHPLC HMW"/>
</coding>
<text value="SE-UHPLC HMW (%)"/>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="7"/>
<unit value="%"/>
</low>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:22515a3c-5034-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- conclusion -->
<id value="22515a3c-5034-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="22515a3c-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "22515a3c-5034-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Conclusion</p><p><b>status</b>: active</p><p><b>code</b>: Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#CONC)</span></p></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/22515a3c-5034-448a-9c19-938ce1958424"/>
<title value="Conclusion"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="CONC"/>
<display value="Conclusion"/>
</coding>
<text value="Conclusion"/>
</code>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:22525a3c-5035-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- conclusionHomogeneity -->
<id value="22525a3c-5035-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="22525a3c-5035-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "22525a3c-5035-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424</code></p><p><b>title</b>: Conclusion</p><p><b>status</b>: active</p><p><b>code</b>: Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#CONC)</span></p></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424"/>
<title value="Conclusion"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="CONC"/>
<display value="Conclusion"/>
</coding>
<text value="Conclusion"/>
</code>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515a3c-5034-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- ThawingOsmolality -->
<id value="64515a3c-5034-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515a3c-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515a3c-5034-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Osmolality</p><p><b>status</b>: active</p><p><b>code</b>: Osmolality (mOsm/kg) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Osmolality "Osmolality")</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>240-310 mOsm/kg</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5034-448a-9c19-938ce1958424"/>
<title value="Osmolality"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Osmolality"/>
<display value="Osmolality"/>
</coding>
<text value="Osmolality (mOsm/kg)"/>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="240"/>
<unit value="mOsm/kg"/>
</low>
<!-- todo UCUM -->
<high>
<value value="310"/>
<unit value="mOsm/kg"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:74515a3c-5034-448a-9c19-938ce1958424"/>
<resource>
<ObservationDefinition>
<!-- ThawingTemp -->
<id value="74515a3c-5034-448a-9c19-938ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="74515a3c-5034-448a-9c19-938ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "74515a3c-5034-448a-9c19-938ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515a3c-5034-448a-9c19-938ce1958424</code></p><p><b>title</b>: Thawing Temp</p><p><b>status</b>: active</p><p><b>code</b>: Thawing Temp (°C) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Thawing Temp "Thawing Temp")</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>20-24 °C</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/74515a3c-5034-448a-9c19-938ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/74515a3c-5034-448a-9c19-938ce1958424"/>
<title value="Thawing Temp"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Thawing Temp"/>
<display value="Thawing Temp"/>
</coding>
<text value="Thawing Temp (°C)"/>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="20"/>
<unit value="°C"/>
</low>
<!-- todo UCUM -->
<high>
<value value="24"/>
<unit value="°C"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515a3c-5134-448a-9c19-939ce1958424"/>
<resource>
<ObservationDefinition>
<!-- Conductivity -->
<id value="64515a3c-5134-448a-9c19-939ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515a3c-5134-448a-9c19-939ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515a3c-5134-448a-9c19-939ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-939ce1958424</code></p><p><b>title</b>: Conductivity</p><p><b>status</b>: active</p><p><b>code</b>: Conductivity (μS/cm) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Conductivity (μS/cm))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>150-200 μS/cm</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-939ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515a3c-5134-448a-9c19-939ce1958424"/>
<title value="Conductivity"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Conductivity (μS/cm)"/>
<display value="Conductivity (μS/cm)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="150"/>
<unit value="μS/cm"/>
</low>
<!-- todo UCUM -->
<high>
<value value="200"/>
<unit value="μS/cm"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:74515a3c-5134-448a-9c19-939ce1958424"/>
<resource>
<ObservationDefinition>
<!-- ThawingConductivity -->
<id value="74515a3c-5134-448a-9c19-939ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="74515a3c-5134-448a-9c19-939ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "74515a3c-5134-448a-9c19-939ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515a3c-5134-448a-9c19-939ce1958424</code></p><p><b>title</b>: Conductivity</p><p><b>status</b>: active</p><p><b>code</b>: Conductivity (μS/cm) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Conductivity (μS/cm))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>150-200 μS/cm</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/74515a3c-5134-448a-9c19-939ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/74515a3c-5134-448a-9c19-939ce1958424"/>
<title value="Conductivity"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Conductivity (μS/cm)"/>
<display value="Conductivity (μS/cm)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="150"/>
<unit value="μS/cm"/>
</low>
<!-- todo UCUM -->
<high>
<value value="200"/>
<unit value="μS/cm"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515b3c-5134-448a-9c19-939ce1958424"/>
<resource>
<ObservationDefinition>
<!-- Bioburden -->
<id value="64515b3c-5134-448a-9c19-939ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515b3c-5134-448a-9c19-939ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515b3c-5134-448a-9c19-939ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958424</code></p><p><b>title</b>: Bioburden</p><p><b>status</b>: active</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>50-150 CFU/ 100 mL</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958424"/>
<title value="Bioburden"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden (CFU/ 100 mL)"/>
<display value="Bioburden (CFU/ 100 mL)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="50"/>
<unit value="CFU/ 100 mL"/>
</low>
<!-- todo UCUM -->
<high>
<value value="150"/>
<unit value="CFU/ 100 mL"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515b3c-5134-448a-9c19-939ce1958524"/>
<resource>
<ObservationDefinition>
<!-- MediaBioburden -->
<id value="64515b3c-5134-448a-9c19-939ce1958524"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515b3c-5134-448a-9c19-939ce1958524"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515b3c-5134-448a-9c19-939ce1958524" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524</code></p><p><b>title</b>: Bioburden</p><p><b>status</b>: active</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-10</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - End)</span></p></blockquote></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524"/>
<title value="Bioburden"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden (CFU/ 100 mL)"/>
<display value="Bioburden (CFU/ 100 mL)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<high>
<value value="10"/>
<unit value="CFU/100 mL"/>
</high>
</range>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - Beginning"/>
<display value="Bioburden - Beginning"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - End"/>
<display value="Bioburden - End"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:74515b3c-5234-448a-9c19-939ce1958524"/>
<resource>
<ObservationDefinition>
<!-- Polysorbate80Concentration -->
<id value="74515b3c-5234-448a-9c19-939ce1958524"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="74515b3c-5234-448a-9c19-939ce1958524"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "74515b3c-5234-448a-9c19-939ce1958524" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524</code></p><p><b>title</b>: Polysorbate 80 Concentration</p><p><b>status</b>: active</p><p><b>code</b>: Polysorbate 80 concentration - Middle - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Max)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>0.5-1.5 % w/v</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Beginning - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - Beginning - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Beginning - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - Beginning - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Middle - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Middle - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - End - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - End - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - End - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - End - Max)</span></p></blockquote></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524"/>
<title value="Polysorbate 80 Concentration"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - Middle - Max"/>
<display value="Polysorbate 80 concentration - Middle - Max"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="0.5"/>
<unit value="% w/v"/>
</low>
<!-- todo UCUM -->
<high>
<value value="1.5"/>
<unit value="% w/v"/>
</high>
</range>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - Beginning - Min"/>
<display
value="Polysorbate 80 concentration - Beginning - Min"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - Beginning - Max"/>
<display
value="Polysorbate 80 concentration - Beginning - Max"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - Middle - Min"/>
<display value="Polysorbate 80 concentration - Middle - Min"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - Middle - Max"/>
<display value="Polysorbate 80 concentration - Middle - Max"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - End - Min"/>
<display value="Polysorbate 80 concentration - End - Min"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - End - Max"/>
<display value="Polysorbate 80 concentration - End - Max"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:74515b3c-5134-448a-9c19-939ce1958524"/>
<resource>
<ObservationDefinition>
<!-- ProteinConcentration -->
<id value="74515b3c-5134-448a-9c19-939ce1958524"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="74515b3c-5134-448a-9c19-939ce1958524"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "74515b3c-5134-448a-9c19-939ce1958524" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524</code></p><p><b>title</b>: Protein Concentration</p><p><b>status</b>: active</p><p><b>code</b>: Protein Concentration (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration (mg/mL))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>8-10 (mg/mL)</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - Max)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - End - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - End - Min)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - End - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - End - Max)</span></p></blockquote></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524"/>
<title value="Protein Concentration"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration (mg/mL)"/>
<display value="Protein Concentration (mg/mL)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="8"/>
<unit value="(mg/mL)"/>
</low>
<!-- todo UCUM -->
<high>
<value value="10"/>
<unit value="(mg/mL)"/>
</high>
</range>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - Min"/>
<display value="Protein Concentration - Beginning - Min"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - Max"/>
<display value="Protein Concentration - Beginning - Max"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - Min"/>
<display value="Protein Concentration - Middle - Min"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - Max"/>
<display value="Protein Concentration - Middle - Max"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - End - Min"/>
<display value="Protein Concentration - End - Min"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - End - Max"/>
<display value="Protein Concentration - End - Max"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:74515b3c-5134-448a-9c19-939ce1958534"/>
<resource>
<ObservationDefinition>
<!-- ProteinConcentrationStats -->
<id value="74515b3c-5134-448a-9c19-939ce1958534"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="74515b3c-5134-448a-9c19-939ce1958534"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "74515b3c-5134-448a-9c19-939ce1958534" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534</code></p><p><b>title</b>: Protein Concentration Stats</p><p><b>status</b>: active</p><p><b>code</b>: Protein Concentration Statistics <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration Statistics)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>8-10 (mg/mL)</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Mean <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Mean)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Mean <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Mean)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Mean <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Mean)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Lower <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Lower)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Lower <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Lower)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Lower <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Lower)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Higher <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Higher)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Higher <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Higher)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Higher <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Higher)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Conclusion)</span></p></blockquote></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534"/>
<title value="Protein Concentration Stats"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration Statistics"/>
<display value="Protein Concentration Statistics"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="8"/>
<unit value="(mg/mL)"/>
</low>
<!-- todo UCUM -->
<high>
<value value="10"/>
<unit value="(mg/mL)"/>
</high>
</range>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code
value="Protein Concentration - Beginning - Middle - Mean"/>
<display
value="Protein Concentration - Beginning - Middle - Mean"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - End - Mean"/>
<display
value="Protein Concentration - Beginning - End - Mean"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - End - Mean"/>
<display value="Protein Concentration - Middle - End - Mean"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code
value="Protein Concentration - Beginning - Middle - Lower"/>
<display
value="Protein Concentration - Beginning - Middle - Lower"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - End - Lower"/>
<display
value="Protein Concentration - Beginning - End - Lower"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - End - Lower"/>
<display value="Protein Concentration - Middle - End - Lower"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code
value="Protein Concentration - Beginning - Middle - Higher"/>
<display
value="Protein Concentration - Beginning - Middle - Higher"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - End - Higher"/>
<display
value="Protein Concentration - Beginning - End - Higher"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - End - Higher"/>
<display value="Protein Concentration - Middle - End - Higher"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Conclusion"/>
<display value="Protein Concentration - Conclusion"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515b3c-5134-448a-9c19-939ce2958524"/>
<resource>
<ObservationDefinition>
<!-- FillWeight -->
<id value="64515b3c-5134-448a-9c19-939ce2958524"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515b3c-5134-448a-9c19-939ce2958524"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515b3c-5134-448a-9c19-939ce2958524" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524</code></p><p><b>title</b>: Fill Weight</p><p><b>status</b>: active</p><p><b>code</b>: Fill Weight <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Fill Weight)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td/><td>95-105 g</td></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - End)</span></p></blockquote></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524"/>
<title value="Fill Weight"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Fill Weight"/>
<display value="Fill Weight"/>
</coding>
</code>
<qualifiedValue>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-target-pq">
<!-- todo UCUM -->
<valueQuantity>
<value value="100"/>
<unit value="g"/>
</valueQuantity>
</extension>
<range>
<!-- todo UCUM -->
<low>
<value value="95"/>
<unit value="g"/>
</low>
<!-- todo UCUM -->
<high>
<value value="105"/>
<unit value="g"/>
</high>
</range>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - Beginning"/>
<display value="Bioburden - Beginning"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - End"/>
<display value="Bioburden - End"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515b3c-5134-448a-9d19-939ce1958524"/>
<resource>
<ObservationDefinition>
<!-- GrowthPromotion -->
<id value="64515b3c-5134-448a-9d19-939ce1958524"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515b3c-5134-448a-9d19-939ce1958524"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515b3c-5134-448a-9d19-939ce1958524" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524</code></p><p><b>title</b>: Growth Promotion</p><p><b>status</b>: active</p><p><b>code</b>: Growth Promotion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#GrowthPromotion)</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td></tr><tr><td style="display: none">*</td><td/></tr></table><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Growth Promotion - Beginning)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Growth Promotion - End)</span></p></blockquote></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524"/>
<title value="Growth Promotion"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="GrowthPromotion"/>
<display value="Growth Promotion"/>
</coding>
</code>
<qualifiedValue>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-qualified-value-text-pq">
<valueString value="Pass"/>
</extension>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Growth Promotion - Beginning"/>
<display value="Growth Promotion - Beginning"/>
</coding>
</code>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Growth Promotion - End"/>
<display value="Growth Promotion - End"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515b3c-5134-448a-9c19-939ce1958434"/>
<resource>
<ObservationDefinition>
<!-- PreFiltrationBioburden -->
<id value="64515b3c-5134-448a-9c19-939ce1958434"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515b3c-5134-448a-9c19-939ce1958434"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515b3c-5134-448a-9c19-939ce1958434" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434</code></p><p><b>title</b>: Pre-filtration Bioburden</p><p><b>status</b>: active</p><p><b>code</b>: Pre-filtration Bioburden (CFU/ 100 mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Pre-filtration Bioburden (CFU/ 100 mL))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>?-150</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958434"/>
<title value="Pre-filtration Bioburden"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Pre-filtration Bioburden (CFU/ 100 mL)"/>
<display value="Pre-filtration Bioburden (CFU/ 100 mL)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<high>
<value value="150"/>
<unit value="CFU/ 100 mL"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515b3c-5134-448a-9c19-949ce1958424"/>
<resource>
<ObservationDefinition>
<!-- BacterialEndotoxins -->
<id value="64515b3c-5134-448a-9c19-949ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515b3c-5134-448a-9c19-949ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515b3c-5134-448a-9c19-949ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958424</code></p><p><b>title</b>: Bacterial Endotoxins</p><p><b>status</b>: active</p><p><b>code</b>: Bacterial Endotoxins (EU/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bacterial Endotoxins (EU/mL))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>40-120 EU/mL</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958424"/>
<title value="Bacterial Endotoxins"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bacterial Endotoxins (EU/mL)"/>
<display value="Bacterial Endotoxins (EU/mL)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="40"/>
<unit value="EU/mL"/>
</low>
<!-- todo UCUM -->
<high>
<value value="120"/>
<unit value="EU/mL"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515b4c-5134-448a-9c19-949ce1958424"/>
<resource>
<ObservationDefinition>
<!-- ThawingBacterialEndotoxins -->
<id value="64515b4c-5134-448a-9c19-949ce1958424"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515b4c-5134-448a-9c19-949ce1958424"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515b4c-5134-448a-9c19-949ce1958424" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b4c-5134-448a-9c19-949ce1958424</code></p><p><b>title</b>: Bacterial Endotoxins</p><p><b>status</b>: active</p><p><b>code</b>: Bacterial Endotoxins (EU/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bacterial Endotoxins (EU/mL))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>50-110 EU/mL</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515b4c-5134-448a-9c19-949ce1958424 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515b4c-5134-448a-9c19-949ce1958424"/>
<title value="Bacterial Endotoxins"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bacterial Endotoxins (EU/mL)"/>
<display value="Bacterial Endotoxins (EU/mL)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="50"/>
<unit value="EU/mL"/>
</low>
<!-- todo UCUM -->
<high>
<value value="110"/>
<unit value="EU/mL"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:74515b3c-5134-448a-9c19-949ce1958434"/>
<resource>
<ObservationDefinition>
<!-- FiltrationPressure -->
<id value="74515b3c-5134-448a-9c19-949ce1958434"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="74515b3c-5134-448a-9c19-949ce1958434"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "74515b3c-5134-448a-9c19-949ce1958434" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434</code></p><p><b>title</b>: Filtration Pressure</p><p><b>status</b>: active</p><p><b>code</b>: FiltrationPressure (psig) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#FiltrationPressure (psig))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>100-150 psig</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/74515b3c-5134-448a-9c19-949ce1958434"/>
<title value="Filtration Pressure"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="FiltrationPressure (psig)"/>
<display value="FiltrationPressure (psig)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="100"/>
<unit value="psig"/>
</low>
<!-- todo UCUM -->
<high>
<value value="150"/>
<unit value="psig"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:75515b3c-5134-448a-9c19-949ce1958434"/>
<resource>
<ObservationDefinition>
<!-- PostFiltrationFilterIntegrity -->
<id value="75515b3c-5134-448a-9c19-949ce1958434"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="75515b3c-5134-448a-9c19-949ce1958434"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "75515b3c-5134-448a-9c19-949ce1958434" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434</code></p><p><b>title</b>: Post-filtration Filter Integrity (psig)</p><p><b>status</b>: active</p><p><b>code</b>: Post-filtration Filter Integrity (psig) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Post-filtration Filter Integrity (psig))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>100-? psig</td></tr></table><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Test Success <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#test-success)</span></td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434"/>
<title value="Post-filtration Filter Integrity (psig)"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Post-filtration Filter Integrity (psig)"/>
<display value="Post-filtration Filter Integrity (psig)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="100"/>
<unit value="psig"/>
</low>
</range>
</qualifiedValue>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="test-success"/>
<display value="Test Success"/>
</coding>
</code>
</component>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:75515c3c-5134-448a-9c19-949ce1958434"/>
<resource>
<ObservationDefinition>
<!-- MediaHoldTime -->
<id value="75515c3c-5134-448a-9c19-949ce1958434"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="75515c3c-5134-448a-9c19-949ce1958434"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "75515c3c-5134-448a-9c19-949ce1958434" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434</code></p><p><b>title</b>: Media Challenge Hold Times (hours)</p><p><b>status</b>: active</p><p><b>code</b>: Media Challenge Hold Times <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Media Challenge Hold Times)</span></p></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434"/>
<title value="Media Challenge Hold Times (hours)"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Media Challenge Hold Times"/>
<display value="Media Challenge Hold Times"/>
</coding>
</code>
</ObservationDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64515b3c-5134-448a-9c19-949ce1958434"/>
<resource>
<ObservationDefinition>
<!-- Polysorbate -->
<id value="64515b3c-5134-448a-9c19-949ce1958434"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: ObservationDefinition</b><a name="64515b3c-5134-448a-9c19-949ce1958434"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ObservationDefinition "64515b3c-5134-448a-9c19-949ce1958434" </p></div><p><b>url</b>: <code>http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958434</code></p><p><b>title</b>: Polysorbate 80</p><p><b>status</b>: active</p><p><b>code</b>: Polysorbate 80 (% w/v) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 (% w/v))</span></p><h3>QualifiedValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>25-55 % w/v</td></tr></table></div>
</text>
<!-- http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958434 -->
<url
value="http://example-server.com/fhir/ObservationDefinition/64515b3c-5134-448a-9c19-949ce1958434"/>
<title value="Polysorbate 80"/>
<status value="active"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 (% w/v)"/>
<display value="Polysorbate 80 (% w/v)"/>
</coding>
</code>
<qualifiedValue>
<range>
<!-- todo UCUM -->
<low>
<value value="25"/>
<unit value="% w/v"/>
</low>
<!-- todo UCUM -->
<high>
<value value="55"/>
<unit value="% w/v"/>
</high>
</range>
</qualifiedValue>
</ObservationDefinition>
</resource>
</entry>
<!-- Section 8 - Batch or Lot Information (batch 1 of 3) -->
<entry>
<fullUrl value="urn:uuid:339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
<resource>
<Medication>
<!-- medication-batch-information-drug-pq-ex1 -->
<id value="339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Medication</b><a name="339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51" </p></div><p><b>code</b>: <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td>, , , , , , , , , , , , </td><td>999909</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name="ppd1-nosubject"> </a></p><p><b>containedItemQuantity</b>: 20 ml</p></blockquote></div>
</text>
<contained>
<PackagedProductDefinition>
<id value="ppd1-nosubject"/>
<containedItemQuantity>
<value value="20"/>
<unit value="ml"/>
</containedItemQuantity>
</PackagedProductDefinition>
</contained>
<code>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
<valueReference>
<!-- todo consider change this be the MID? -->
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq">
<valueReference>
<reference value="#ppd1-nosubject"/>
</valueReference>
</extension>
</code>
<!-- totalVolume -->
<!-- considered this as presentation (package size). Unclear how to use it, esp. for non-liquids -->
<batch>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="manufacturingDate">
<valueDateTime value="2020-06-01"/>
</extension>
<extension url="batchQuantity">
<valueQuantity>
<value value="100100"/>
<unit value="tablets"/>
</valueQuantity>
</extension>
<extension url="batchUtilization">
<valueCodeableConcept>
<coding>
<system
value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
<code value="C185328"/>
<display value="Stability Study"/>
</coding>
<text value="PPQ / Stability"/>
</valueCodeableConcept>
</extension>
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/manufacturer -->
<reference
value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
</valueReference>
</extension>
<extension url="container">
<extension url="closureSystemDescription">
<valueString value="100 cc HDPE Bottle 2 g desiccant"/>
</extension>
</extension>
</extension>
<!-- local extensions -->
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
<valueDateTime value="2019-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq">
<valueString value="1333224444"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq">
<valueCodeableConcept>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-batch-designation-local-pq"/>
<code value="minimum"/>
<display value="Minimum"/>
</coding>
<text value="Minimum"/>
</valueCodeableConcept>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq">
<valuePositiveInt value="3"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-full-shelves-pq">
<valuePositiveInt value="4"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-partial-shelves-pq">
<valuePositiveInt value="5"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq">
<valueReference>
<!-- Substance/substance-dxpq-ex1 -->
<reference
value="Substance/fc078762-81c5-5656-9744-13c7ad1e595b"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq">
<valueDateTime value="2020-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq">
<valueReference>
<!-- Organization/packaging -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
<valueQuantity>
<value value="4.81"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq">
<valueQuantity>
<value value="4.91"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq">
<valueQuantity>
<value value="30"/>
<unit value="g"/>
</valueQuantity>
</extension>
<lotNumber value="999909"/>
</batch>
</Medication>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51"/>
<resource>
<Medication>
<!-- medication-batch-information-drug-pq-ex1b-unlinked -->
<id value="339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Medication</b><a name="339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "339b69fd-4ab1-a1e9-9ea5-1973ba2f6b51" </p></div><p><b>code</b>: <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td>, , , , , , , , , , </td><td>999910</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name="ppd1-nosubject"> </a></p><p><b>containedItemQuantity</b>: 50 ml</p></blockquote></div>
</text>
<contained>
<PackagedProductDefinition>
<id value="ppd1-nosubject"/>
<containedItemQuantity>
<value value="50"/>
<unit value="ml"/>
</containedItemQuantity>
</PackagedProductDefinition>
</contained>
<code>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
<valueReference>
<!-- todo consider change this be the MID? -->
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq">
<valueReference>
<reference value="#ppd1-nosubject"/>
</valueReference>
</extension>
</code>
<batch>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="manufacturingDate">
<valueDateTime value="2020-06-02"/>
</extension>
<extension url="batchQuantity">
<valueQuantity>
<value value="100100"/>
<unit value="tablets"/>
</valueQuantity>
</extension>
<extension url="batchUtilization">
<valueCodeableConcept>
<coding>
<system
value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
<code value="C185328"/>
<display value="Stability Study"/>
</coding>
<text value="PPQ / Stability"/>
</valueCodeableConcept>
</extension>
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/manufacturer -->
<reference
value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
</valueReference>
</extension>
<extension url="container">
<extension url="closureSystemDescription">
<valueString value="100 cc HDPE Bottle 2 g desiccant"/>
</extension>
</extension>
</extension>
<!-- local extensions -->
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
<valueDateTime value="2019-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq">
<valueString value="1333224444"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq">
<valueCodeableConcept>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-batch-designation-local-pq"/>
<code value="maximum"/>
<display value="Maximum"/>
</coding>
<text value="Maximum"/>
</valueCodeableConcept>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq">
<valuePositiveInt value="3"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq">
<valueReference>
<!-- Substance/substance-dxpq-ex1 -->
<reference
value="Substance/fc078762-81c5-5656-9744-13c7ad1e595b"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq">
<valueDateTime value="2020-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq">
<valueReference>
<!-- Organization/packaging -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
<valueQuantity>
<value value="4.81"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq">
<valueQuantity>
<value value="4.91"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq">
<valueQuantity>
<value value="30"/>
<unit value="g"/>
</valueQuantity>
</extension>
<lotNumber value="999910"/>
</batch>
</Medication>
</resource>
</entry>
<!-- Section 8 - Batch or Lot Information (another batch 2 of 3) -->
<entry>
<fullUrl value="urn:uuid:a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
<resource>
<Medication>
<!-- medication-actual-batch-2 -->
<id value="a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Medication</b><a name="a9dfda53-734b-045f-7ae4-94a6281d53bc"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "a9dfda53-734b-045f-7ae4-94a6281d53bc" </p></div><p><b>code</b>: <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td>, , , , , , , , , , </td><td>999911</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name="ppd1-nosubject"> </a></p><p><b>containedItemQuantity</b>: 20 ml</p></blockquote></div>
</text>
<contained>
<PackagedProductDefinition>
<id value="ppd1-nosubject"/>
<containedItemQuantity>
<value value="20"/>
<unit value="ml"/>
</containedItemQuantity>
</PackagedProductDefinition>
</contained>
<code>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
<valueReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq">
<valueReference>
<reference value="#ppd1-nosubject"/>
</valueReference>
</extension>
</code>
<batch>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="manufacturingDate">
<valueDateTime value="2020-06-01"/>
</extension>
<extension url="batchQuantity">
<valueQuantity>
<value value="100050"/>
<unit value="tablets"/>
</valueQuantity>
</extension>
<extension url="batchUtilization">
<valueCodeableConcept>
<coding>
<system
value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
<code value="C185328"/>
<display value="Stability Study"/>
</coding>
<text value="PPQ / Stability"/>
</valueCodeableConcept>
</extension>
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/manufacturer -->
<reference
value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
</valueReference>
</extension>
<extension url="container">
<extension url="closureSystemDescription">
<valueString value="100 cc HDPE Bottle 2 g desiccant"/>
</extension>
</extension>
</extension>
<!-- local extensions -->
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
<valueDateTime value="2019-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq">
<valueString value="1333225555"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq">
<valueCodeableConcept>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-batch-designation-local-pq"/>
<code value="maximum"/>
<display value="Maximum"/>
</coding>
<text value="Maximum"/>
</valueCodeableConcept>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq">
<valuePositiveInt value="4"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq">
<valueReference>
<!-- Substance/actual-batch-substance-2 -->
<reference
value="Substance/cb31d747-2338-88d5-342c-8e9c097e4dad"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq">
<valueDateTime value="2020-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq">
<valueReference>
<!-- Organization/packaging -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
<valueQuantity>
<value value="4.82"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq">
<valueQuantity>
<value value="4.92"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq">
<valueQuantity>
<value value="30"/>
<unit value="g"/>
</valueQuantity>
</extension>
<lotNumber value="999911"/>
</batch>
</Medication>
</resource>
</entry>
<!-- Section 8 - Batch or Lot Information (another batch 2 of 3) -->
<entry>
<fullUrl value="urn:uuid:a9dfda53-734b-045f-7ae5-94a6281d53bc"/>
<resource>
<Medication>
<!-- medication-actual-batch-2b-unlinked -->
<id value="a9dfda53-734b-045f-7ae5-94a6281d53bc"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Medication</b><a name="a9dfda53-734b-045f-7ae5-94a6281d53bc"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "a9dfda53-734b-045f-7ae5-94a6281d53bc" </p></div><p><b>code</b>: <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td>, , , , , , , , , , </td><td>999912</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name="ppd1-nosubject"> </a></p><p><b>containedItemQuantity</b>: 50 ml</p></blockquote></div>
</text>
<contained>
<PackagedProductDefinition>
<id value="ppd1-nosubject"/>
<containedItemQuantity>
<value value="50"/>
<unit value="ml"/>
</containedItemQuantity>
</PackagedProductDefinition>
</contained>
<code>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
<valueReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq">
<valueReference>
<reference value="#ppd1-nosubject"/>
</valueReference>
</extension>
</code>
<batch>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="manufacturingDate">
<valueDateTime value="2020-06-02"/>
</extension>
<extension url="batchQuantity">
<valueQuantity>
<value value="100050"/>
<unit value="tablets"/>
</valueQuantity>
</extension>
<extension url="batchUtilization">
<valueCodeableConcept>
<coding>
<system
value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
<code value="C185328"/>
<display value="Stability Study"/>
</coding>
<text value="PPQ / Stability"/>
</valueCodeableConcept>
</extension>
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/manufacturer -->
<reference
value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
</valueReference>
</extension>
<extension url="container">
<extension url="closureSystemDescription">
<valueString value="100 cc HDPE Bottle 2 g desiccant"/>
</extension>
</extension>
</extension>
<!-- local extensions -->
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
<valueDateTime value="2019-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq">
<valueString value="1333225555"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq">
<valueCodeableConcept>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-batch-designation-local-pq"/>
<code value="maximum"/>
<display value="Maximum"/>
</coding>
<text value="Maximum"/>
</valueCodeableConcept>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq">
<valuePositiveInt value="4"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq">
<valueReference>
<!-- Substance/actual-batch-substance-2 -->
<reference
value="Substance/cb31d747-2338-88d5-342c-8e9c097e4dad"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq">
<valueDateTime value="2020-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq">
<valueReference>
<!-- Organization/packaging -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
<valueQuantity>
<value value="4.82"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq">
<valueQuantity>
<value value="4.92"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq">
<valueQuantity>
<value value="30"/>
<unit value="g"/>
</valueQuantity>
</extension>
<lotNumber value="999912"/>
</batch>
</Medication>
</resource>
</entry>
<!-- Section 8 - Batch or Lot Information (another batch 3 of 3) -->
<entry>
<fullUrl value="urn:uuid:c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
<resource>
<Medication>
<!-- medication-actual-batch-3 -->
<id value="c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Medication</b><a name="c6f5fadd-62e6-3a01-93d9-b3b182f67d06"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "c6f5fadd-62e6-3a01-93d9-b3b182f67d06" </p></div><p><b>code</b>: <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td>, , , , , , , , , , </td><td>999913</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name="ppd1-nosubject"> </a></p><p><b>containedItemQuantity</b>: 20 ml</p></blockquote></div>
</text>
<contained>
<PackagedProductDefinition>
<id value="ppd1-nosubject"/>
<containedItemQuantity>
<value value="20"/>
<unit value="ml"/>
</containedItemQuantity>
</PackagedProductDefinition>
</contained>
<code>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
<valueReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq">
<valueReference>
<reference value="#ppd1-nosubject"/>
</valueReference>
</extension>
</code>
<batch>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="manufacturingDate">
<valueDateTime value="2020-06-01"/>
</extension>
<extension url="batchQuantity">
<valueQuantity>
<value value="100125"/>
<unit value="tablets"/>
</valueQuantity>
</extension>
<extension url="batchUtilization">
<valueCodeableConcept>
<coding>
<system
value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
<code value="C185328"/>
<display value="Stability Study"/>
</coding>
<text value="PPQ / Stability"/>
</valueCodeableConcept>
</extension>
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/manufacturer -->
<reference
value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
</valueReference>
</extension>
<extension url="container">
<extension url="closureSystemDescription">
<valueString value="100 cc HDPE Bottle 2 g desiccant"/>
</extension>
</extension>
</extension>
<!-- local extension -->
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
<valueDateTime value="2019-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq">
<valueString value="1333226666"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq">
<valueCodeableConcept>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-batch-designation-local-pq"/>
<code value="maximum"/>
<display value="Maximum"/>
</coding>
<text value="Maximum"/>
</valueCodeableConcept>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq">
<valuePositiveInt value="3"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq">
<valueReference>
<!-- Substance/actual-batch-substance-3 -->
<reference
value="Substance/1551f97b-6f6d-825e-1fb3-44b0b090808c"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq">
<valueDateTime value="2020-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq">
<valueReference>
<!-- Organization/packaging -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
<valueQuantity>
<value value="4.83"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq">
<valueQuantity>
<value value="4.93"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq">
<valueQuantity>
<value value="30"/>
<unit value="g"/>
</valueQuantity>
</extension>
<lotNumber value="999913"/>
</batch>
</Medication>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:c6f5fadd-62e6-3a11-93d9-b3b182f67d06"/>
<resource>
<Medication>
<!-- medication-actual-batch-3b-unlinked -->
<id value="c6f5fadd-62e6-3a11-93d9-b3b182f67d06"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Medication</b><a name="c6f5fadd-62e6-3a11-93d9-b3b182f67d06"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "c6f5fadd-62e6-3a11-93d9-b3b182f67d06" </p></div><p><b>code</b>: <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td>, , , , , , , , , , </td><td>999914</td></tr></table><hr/><blockquote><p><b>Generated Narrative: PackagedProductDefinition #ppd1-nosubject</b><a name="ppd1-nosubject"> </a></p><p><b>containedItemQuantity</b>: 50 ml</p></blockquote></div>
</text>
<contained>
<PackagedProductDefinition>
<id value="ppd1-nosubject"/>
<containedItemQuantity>
<value value="50"/>
<unit value="ml"/>
</containedItemQuantity>
</PackagedProductDefinition>
</contained>
<code>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
<valueReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-package-definition-pq">
<valueReference>
<reference value="#ppd1-nosubject"/>
</valueReference>
</extension>
</code>
<batch>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="manufacturingDate">
<valueDateTime value="2020-06-02"/>
</extension>
<extension url="batchQuantity">
<valueQuantity>
<value value="100125"/>
<unit value="tablets"/>
</valueQuantity>
</extension>
<extension url="batchUtilization">
<valueCodeableConcept>
<coding>
<system
value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
<code value="C185328"/>
<display value="Stability Study"/>
</coding>
<text value="PPQ / Stability"/>
</valueCodeableConcept>
</extension>
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/manufacturer -->
<reference
value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
</valueReference>
</extension>
<extension url="container">
<extension url="closureSystemDescription">
<valueString value="100 cc HDPE Bottle 2 g desiccant"/>
</extension>
</extension>
</extension>
<!-- local extension -->
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
<valueDateTime value="2019-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-formulation-number-pq">
<valueString value="1333226666"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-designation-pq">
<valueCodeableConcept>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-batch-designation-local-pq"/>
<code value="intermediate"/>
<display value="Intermediate"/>
</coding>
<text value="Intermediate"/>
</valueCodeableConcept>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-number-of-vials-pq">
<valuePositiveInt value="3"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-substance-batch-pq">
<valueReference>
<!-- Substance/actual-batch-substance-3 -->
<reference
value="Substance/1551f97b-6f6d-825e-1fb3-44b0b090808c"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-date-pq">
<valueDateTime value="2020-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-packaging-site-pq">
<valueReference>
<!-- Organization/packaging -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b07"/>
</valueReference>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
<valueQuantity>
<value value="4.83"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-unfiltered-pq">
<valueQuantity>
<value value="4.93"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-target-fill-weight-pq">
<valueQuantity>
<value value="30"/>
<unit value="g"/>
</valueQuantity>
</extension>
<lotNumber value="999914"/>
</batch>
</Medication>
</resource>
</entry>
<!-- Section 4.1 - Manufacturer -->
<entry>
<fullUrl value="urn:uuid:0102bca4-46c1-a6bf-1025-cd403fee710a"/>
<resource>
<Organization>
<!-- manufacturer -->
<id value="0102bca4-46c1-a6bf-1025-cd403fee710a"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Organization</b><a name="0102bca4-46c1-a6bf-1025-cd403fee710a"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization "0102bca4-46c1-a6bf-1025-cd403fee710a" </p></div><p><b>identifier</b>: id: 3010027650</p><p><b>name</b>: AAA Pharmaceutical, Inc.</p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Address</b></td></tr><tr><td style="display: none">*</td><td>681 Main Street Lumberton New Jersey 08048 USA </td></tr></table></div>
</text>
<identifier>
<!-- FDA establishment identifier -->
<system value="urn:oid:2.16.840.1.113883.4.82"/>
<value value="3010027650"/>
</identifier>
<name value="AAA Pharmaceutical, Inc."/>
<contact>
<address>
<line value="681 Main Street"/>
<city value="Lumberton"/>
<state value="New Jersey"/>
<postalCode value="08048"/>
<country value="USA"/>
</address>
</contact>
</Organization>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:378fbe5f-5926-3a5c-4c64-5428df877b07"/>
<resource>
<Organization>
<!-- packaging -->
<id value="378fbe5f-5926-3a5c-4c64-5428df877b07"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Organization</b><a name="378fbe5f-5926-3a5c-4c64-5428df877b07"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization "378fbe5f-5926-3a5c-4c64-5428df877b07" </p></div><p><b>name</b>: MySite</p></div>
</text>
<name value="MySite"/>
</Organization>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:9c56948a-2a39-6609-1c01-4d197ea57a33"/>
<resource>
<Observation>
<!-- bufferVesselMixingSpeed1 -->
<id value="9c56948a-2a39-6609-1c01-4d197ea57a33"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="9c56948a-2a39-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "9c56948a-2a39-6609-1c01-4d197ea57a33" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fd17b5d6-9fe1-91c2-2d06-47cb5b295e72">See above (ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72)</a></p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing speed (rpm) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Buffer vessel mixing speed (rpm))</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 205 rpm</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/bufferVesselMixingSpeed -->
<reference
value="ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Buffer vessel mixing speed (rpm)"/>
<display value="Buffer vessel mixing speed (rpm)"/>
</coding>
<text value="Buffer vessel mixing speed (rpm)"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="205"/>
<unit value="rpm"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:9c56948a-3a39-6609-1c01-4d197ea57a33"/>
<resource>
<Observation>
<!-- bufferVesselMixingSpeed2 -->
<id value="9c56948a-3a39-6609-1c01-4d197ea57a33"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="9c56948a-3a39-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "9c56948a-3a39-6609-1c01-4d197ea57a33" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fd17b5d6-9fe1-91c2-2d06-47cb5b295e72">See above (ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72)</a></p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing speed (rpm) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Buffer vessel mixing speed (rpm))</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 210 rpm</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/bufferVesselMixingSpeed -->
<reference
value="ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Buffer vessel mixing speed (rpm)"/>
<display value="Buffer vessel mixing speed (rpm)"/>
</coding>
<text value="Buffer vessel mixing speed (rpm)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="210"/>
<unit value="rpm"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:9c56948a-4a39-6609-1c01-4d197ea57a33"/>
<resource>
<Observation>
<!-- bufferVesselMixingSpeed3 -->
<id value="9c56948a-4a39-6609-1c01-4d197ea57a33"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="9c56948a-4a39-6609-1c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "9c56948a-4a39-6609-1c01-4d197ea57a33" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fd17b5d6-9fe1-91c2-2d06-47cb5b295e72">See above (ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72)</a></p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing speed (rpm) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Buffer vessel mixing speed (rpm))</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 198 rpm</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/bufferVesselMixingSpeed -->
<reference
value="ObservationDefinition/fd17b5d6-9fe1-91c2-2d06-47cb5b295e72"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Buffer vessel mixing speed (rpm)"/>
<display value="Buffer vessel mixing speed (rpm)"/>
</coding>
<text value="Buffer vessel mixing speed (rpm)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="198"/>
<unit value="rpm"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:9c56948a-2a39-6609-2c01-4d197ea57a33"/>
<resource>
<Observation>
<!-- bufferVesselMixingTime1 -->
<id value="9c56948a-2a39-6609-2c01-4d197ea57a33"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="9c56948a-2a39-6609-2c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "9c56948a-2a39-6609-2c01-4d197ea57a33" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fc17b5d5-9fe1-91c2-2d06-47cb5b295e73">See above (ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73)</a></p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing time (min) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Buffer vessel mixing time (min))</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 51 mins</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/bufferVesselMixingTime -->
<reference
value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Buffer vessel mixing time (min)"/>
<display value="Buffer vessel mixing time (min)"/>
</coding>
<text value="Buffer vessel mixing time (min)"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="51"/>
<unit value="mins"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:9c56948a-3a39-6609-2c01-4d197ea57a33"/>
<resource>
<Observation>
<!-- bufferVesselMixingTime2 -->
<id value="9c56948a-3a39-6609-2c01-4d197ea57a33"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="9c56948a-3a39-6609-2c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "9c56948a-3a39-6609-2c01-4d197ea57a33" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fc17b5d5-9fe1-91c2-2d06-47cb5b295e73">See above (ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73)</a></p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing time (min) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Buffer vessel mixing time (min))</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 49 mins</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/bufferVesselMixingTime -->
<reference
value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Buffer vessel mixing time (min)"/>
<display value="Buffer vessel mixing time (min)"/>
</coding>
<text value="Buffer vessel mixing time (min)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="49"/>
<unit value="mins"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:9c56948a-4a39-6609-3c01-4d197ea57a33"/>
<resource>
<Observation>
<!-- bufferVesselMixingTime3 -->
<id value="9c56948a-4a39-6609-3c01-4d197ea57a33"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="9c56948a-4a39-6609-3c01-4d197ea57a33"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "9c56948a-4a39-6609-3c01-4d197ea57a33" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fc17b5d5-9fe1-91c2-2d06-47cb5b295e73">See above (ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73)</a></p><p><b>status</b>: final</p><p><b>code</b>: Buffer vessel mixing time (min) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Buffer vessel mixing time (min))</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 52 mins</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/bufferVesselMixingTime -->
<reference
value="ObservationDefinition/fc17b5d5-9fe1-91c2-2d06-47cb5b295e73"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Buffer vessel mixing time (min)"/>
<display value="Buffer vessel mixing time (min)"/>
</coding>
<text value="Buffer vessel mixing time (min)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="52"/>
<unit value="mins"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-4f96-6495-b2bec7f160e7"/>
<resource>
<Observation>
<!-- ph1 -->
<id value="44aa47fd-8964-4f96-6495-b2bec7f160e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44aa47fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44aa47fd-8964-4f96-6495-b2bec7f160e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fc17b5d6-9fe1-91c2-2d16-47cb5b295e72">See above (ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72)</a></p><p><b>status</b>: final</p><p><b>code</b>: pH <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#pH)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 6.9 pH</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/FBPPIpH -->
<reference
value="ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="pH"/>
<display value="pH"/>
</coding>
<text value="pH"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="6.9"/>
<unit value="pH"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54aa47fd-8964-4f96-6495-b2bec7f160e7"/>
<resource>
<Observation>
<!-- ph2 -->
<id value="54aa47fd-8964-4f96-6495-b2bec7f160e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54aa47fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54aa47fd-8964-4f96-6495-b2bec7f160e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fc17b5d6-9fe1-91c2-2d16-47cb5b295e72">See above (ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72)</a></p><p><b>status</b>: final</p><p><b>code</b>: pH <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#pH)</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 7.1 pH</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/FBPPIpH -->
<reference
value="ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="pH"/>
<display value="pH"/>
</coding>
<text value="pH"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="7.1"/>
<unit value="pH"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54aa48fd-8964-4f96-6495-b2bec7f160e7"/>
<resource>
<Observation>
<!-- ph3 -->
<id value="54aa48fd-8964-4f96-6495-b2bec7f160e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54aa48fd-8964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54aa48fd-8964-4f96-6495-b2bec7f160e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fc17b5d6-9fe1-91c2-2d16-47cb5b295e72">See above (ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72)</a></p><p><b>status</b>: final</p><p><b>code</b>: pH <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#pH)</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 7.2 pH</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/FBPPIpH -->
<reference
value="ObservationDefinition/fc17b5d6-9fe1-91c2-2d16-47cb5b295e72"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="pH"/>
<display value="pH"/>
</coding>
<text value="pH"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="7.2"/>
<unit value="pH"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-9964-5f96-6495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- mediaChallengeHoldTimesStep1 -->
<id value="44aa47fd-9964-5f96-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44aa47fd-9964-5f96-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44aa47fd-9964-5f96-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_75515c3c-5134-448a-9c19-949ce1958434">See above (ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434)</a></p><p><b>status</b>: final</p><p><b>code</b>: Hold Time (hr) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Hold Time "Hold Time")</span></p><p><b>subject</b>: <a href="#Procedure_44aa47fd-8964-5f96-8495-b2bec7f161a8">See above (Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 1.25 hours</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/MediaHoldTime -->
<reference
value="ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Hold Time"/>
<display value="Hold Time"/>
</coding>
<text value="Hold Time (hr)"/>
</code>
<subject>
<!-- Procedure/procedure-drug-pq-ex1 -->
<reference value="Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="1.25"/>
<unit value="hours"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-5f96-6495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- mediaChallengeHoldTimesStep2 -->
<id value="44aa47fd-8964-5f96-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44aa47fd-8964-5f96-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44aa47fd-8964-5f96-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_75515c3c-5134-448a-9c19-949ce1958434">See above (ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434)</a></p><p><b>status</b>: final</p><p><b>code</b>: Hold Time (hr) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Hold Time "Hold Time")</span></p><p><b>subject</b>: <a href="#Procedure_44aa47fd-8964-5f96-6495-b2bec7f162a8">See above (Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 1.5 hours</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/MediaHoldTime -->
<reference
value="ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Hold Time"/>
<display value="Hold Time"/>
</coding>
<text value="Hold Time (hr)"/>
</code>
<subject>
<!-- Procedure/procedure-run-2 -->
<reference value="Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="1.5"/>
<unit value="hours"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-5f96-7495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- mediaChallengeHoldTimesStep3 -->
<id value="44aa47fd-8964-5f96-7495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44aa47fd-8964-5f96-7495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44aa47fd-8964-5f96-7495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_75515c3c-5134-448a-9c19-949ce1958434">See above (ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434)</a></p><p><b>status</b>: final</p><p><b>code</b>: Hold Time (hr) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Hold Time "Hold Time")</span></p><p><b>subject</b>: <a href="#Procedure_44aa47fd-8964-5f96-6495-b2bec7f163a8">See above (Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 1.75 hours</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/MediaHoldTime -->
<reference
value="ObservationDefinition/75515c3c-5134-448a-9c19-949ce1958434"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Hold Time"/>
<display value="Hold Time"/>
</coding>
<text value="Hold Time (hr)"/>
</code>
<subject>
<!-- Procedure/procedure-run-3 -->
<reference value="Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="1.75"/>
<unit value="hours"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-9964-5f97-6495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- mediaChallengeBioburden1 -->
<id value="44aa47fd-9964-5f97-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44aa47fd-9964-5f97-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44aa47fd-9964-5f97-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64515b3c-5134-448a-9c19-939ce1958524">See above (ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524)</a></p><p><b>status</b>: final</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><p><b>subject</b>: <a href="#Procedure_44aa47fd-8964-5f96-8495-b2bec7f161a8">See above (Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p><p><b>value</b>: 8.0 CFU/100 mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - End)</span></p><p><b>value</b>: 9.0 CFU/100 mL</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/MediaBioburden -->
<reference
value="ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden (CFU/ 100 mL)"/>
<display value="Bioburden (CFU/ 100 mL)"/>
</coding>
</code>
<subject>
<!-- Procedure/procedure-drug-pq-ex1 -->
<reference value="Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - Beginning"/>
<display value="Bioburden - Beginning"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.0"/>
<unit value="CFU/100 mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - End"/>
<display value="Bioburden - End"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="9.0"/>
<unit value="CFU/100 mL"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-5f98-6495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- mediaChallengeBioburden2 -->
<id value="44aa47fd-8964-5f98-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44aa47fd-8964-5f98-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44aa47fd-8964-5f98-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64515b3c-5134-448a-9c19-939ce1958524">See above (ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524)</a></p><p><b>status</b>: final</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><p><b>subject</b>: <a href="#Procedure_44aa47fd-8964-5f96-6495-b2bec7f162a8">See above (Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p><p><b>value</b>: 8.5 CFU/100 mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - End)</span></p><p><b>value</b>: 8.6 CFU/100 mL</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/MediaBioburden -->
<reference
value="ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden (CFU/ 100 mL)"/>
<display value="Bioburden (CFU/ 100 mL)"/>
</coding>
</code>
<subject>
<!-- Procedure/procedure-run-2 -->
<reference value="Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - Beginning"/>
<display value="Bioburden - Beginning"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.5"/>
<unit value="CFU/100 mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - End"/>
<display value="Bioburden - End"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.6"/>
<unit value="CFU/100 mL"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-5f99-7495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- mediaChallengeBioburden3 -->
<id value="44aa47fd-8964-5f99-7495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44aa47fd-8964-5f99-7495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44aa47fd-8964-5f99-7495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64515b3c-5134-448a-9c19-939ce1958524">See above (ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524)</a></p><p><b>status</b>: final</p><p><b>code</b>: Bioburden (CFU/ 100 mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden (CFU/ 100 mL))</span></p><p><b>subject</b>: <a href="#Procedure_44aa47fd-8964-5f96-6495-b2bec7f163a8">See above (Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - Beginning)</span></p><p><b>value</b>: 9.5 CFU/100 mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Bioburden - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Bioburden - End)</span></p><p><b>value</b>: 10.1 CFU/100 mL</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/MediaBioburden -->
<reference
value="ObservationDefinition/64515b3c-5134-448a-9c19-939ce1958524"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden (CFU/ 100 mL)"/>
<display value="Bioburden (CFU/ 100 mL)"/>
</coding>
</code>
<subject>
<!-- Procedure/procedure-run-3 -->
<reference value="Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - Beginning"/>
<display value="Bioburden - Beginning"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="9.5"/>
<unit value="CFU/100 mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Bioburden - End"/>
<display value="Bioburden - End"/>
</coding>
</code>
<!-- todproteinConcentration1o UCUM -->
<valueQuantity>
<value value="10.1"/>
<unit value="CFU/100 mL"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54aa47fd-9965-5f97-6495-b2bec8f161e8"/>
<resource>
<Observation>
<!-- proteinConcentrationStats1 -->
<id value="54aa47fd-9965-5f97-6495-b2bec8f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54aa47fd-9965-5f97-6495-b2bec8f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54aa47fd-9965-5f97-6495-b2bec8f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_74515b3c-5134-448a-9c19-939ce1958534">See above (ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534)</a></p><p><b>status</b>: final</p><p><b>code</b>: Protein Concentration (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration (mg/mL))</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Mean <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Mean)</span></p><p><b>value</b>: 8.0 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Mean <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Mean)</span></p><p><b>value</b>: 8.05 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Mean <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Mean)</span></p><p><b>value</b>: 8.10 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Lower <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Lower)</span></p><p><b>value</b>: 8.15 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Lower <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Lower)</span></p><p><b>value</b>: 8.2 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Lower <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Lower)</span></p><p><b>value</b>: 8.25 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Middle - Higher <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Middle - Higher)</span></p><p><b>value</b>: 8.45 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - End - Higher <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - End - Higher)</span></p><p><b>value</b>: 8.3 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - End - Higher <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - End - Higher)</span></p><p><b>value</b>: 8.35 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Conclusion)</span></p><p><b>value</b>: Pass</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/ProteinConcentrationStats -->
<reference
value="ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958534"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration (mg/mL)"/>
<display value="Protein Concentration (mg/mL)"/>
</coding>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code
value="Protein Concentration - Beginning - Middle - Mean"/>
<display
value="Protein Concentration - Beginning - Middle - Mean"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.0"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - End - Mean"/>
<display
value="Protein Concentration - Beginning - End - Mean"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.05"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - End - Mean"/>
<display value="Protein Concentration - Middle - End - Mean"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.10"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code
value="Protein Concentration - Beginning - Middle - Lower"/>
<display
value="Protein Concentration - Beginning - Middle - Lower"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.15"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - End - Lower"/>
<display
value="Protein Concentration - Beginning - End - Lower"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.2"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - End - Lower"/>
<display value="Protein Concentration - Middle - End - Lower"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.25"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code
value="Protein Concentration - Beginning - Middle - Higher"/>
<display
value="Protein Concentration - Beginning - Middle - Higher"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.45"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - End - Higher"/>
<display
value="Protein Concentration - Beginning - End - Higher"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.3"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - End - Higher"/>
<display value="Protein Concentration - Middle - End - Higher"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.35"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Conclusion"/>
<display value="Protein Concentration - Conclusion"/>
</coding>
</code>
<valueString value="Pass"/>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54aa47fd-9964-5f97-6495-b2bec8f161e8"/>
<resource>
<Observation>
<!-- proteinConcentration1 -->
<id value="54aa47fd-9964-5f97-6495-b2bec8f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54aa47fd-9964-5f97-6495-b2bec8f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54aa47fd-9964-5f97-6495-b2bec8f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_74515b3c-5134-448a-9c19-939ce1958524">See above (ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524)</a></p><p><b>status</b>: final</p><p><b>code</b>: Protein Concentration (mg/mL) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration (mg/mL))</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Min)</span></p><p><b>value</b>: 8.00 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Beginning - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Beginning - Max)</span></p><p><b>value</b>: 8.05 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - Min)</span></p><p><b>value</b>: 8.10 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - Middle - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - Middle - Max)</span></p><p><b>value</b>: 8.15 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - End - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - End - Min)</span></p><p><b>value</b>: 8.2 mg/mL</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Protein Concentration - End - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Protein Concentration - End - Max)</span></p><p><b>value</b>: 8.25 mg/mL</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/ProteinConcentration -->
<reference
value="ObservationDefinition/74515b3c-5134-448a-9c19-939ce1958524"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration (mg/mL)"/>
<display value="Protein Concentration (mg/mL)"/>
</coding>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - Min"/>
<display value="Protein Concentration - Beginning - Min"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.00"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Beginning - Max"/>
<display value="Protein Concentration - Beginning - Max"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.05"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - Min"/>
<display value="Protein Concentration - Middle - Min"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.10"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - Middle - Max"/>
<display value="Protein Concentration - Middle - Max"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.15"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - End - Min"/>
<display value="Protein Concentration - End - Min"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.2"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Protein Concentration - End - Max"/>
<display value="Protein Concentration - End - Max"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="8.25"/>
<unit value="mg/mL"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54aa47fd-9964-5f97-6495-b2bec8f162e8"/>
<resource>
<Observation>
<!-- polysorbate2 -->
<id value="54aa47fd-9964-5f97-6495-b2bec8f162e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54aa47fd-9964-5f97-6495-b2bec8f162e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54aa47fd-9964-5f97-6495-b2bec8f162e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_74515b3c-5234-448a-9c19-939ce1958524">See above (ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524)</a></p><p><b>status</b>: final</p><p><b>code</b>: Polysorbate 80 concentration (% w/v) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration (% w/v))</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Beginning - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - Beginning - Min)</span></p><p><b>value</b>: 1.0 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Beginning - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - Beginning - Max)</span></p><p><b>value</b>: 1.05 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Middle - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Min)</span></p><p><b>value</b>: 1.10 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - Middle - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - Middle - Max)</span></p><p><b>value</b>: 1.15 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - End - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - End - Min)</span></p><p><b>value</b>: 1.2 % w/v</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Polysorbate 80 concentration - End - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Polysorbate 80 concentration - End - Max)</span></p><p><b>value</b>: 1.25 % w/v</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/Polysorbate80Concentration -->
<reference
value="ObservationDefinition/74515b3c-5234-448a-9c19-939ce1958524"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration (% w/v)"/>
<display value="Polysorbate 80 concentration (% w/v)"/>
</coding>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - Beginning - Min"/>
<display
value="Polysorbate 80 concentration - Beginning - Min"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="1.0"/>
<unit value="% w/v"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - Beginning - Max"/>
<display
value="Polysorbate 80 concentration - Beginning - Max"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="1.05"/>
<unit value="% w/v"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - Middle - Min"/>
<display value="Polysorbate 80 concentration - Middle - Min"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="1.10"/>
<unit value="% w/v"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - Middle - Max"/>
<display value="Polysorbate 80 concentration - Middle - Max"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="1.15"/>
<unit value="% w/v"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - End - Min"/>
<display value="Polysorbate 80 concentration - End - Min"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="1.2"/>
<unit value="% w/v"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Polysorbate 80 concentration - End - Max"/>
<display value="Polysorbate 80 concentration - End - Max"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="1.25"/>
<unit value="% w/v"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54aa47fd-9964-5f97-6495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- growthPromotion1 -->
<id value="54aa47fd-9964-5f97-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54aa47fd-9964-5f97-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54aa47fd-9964-5f97-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64515b3c-5134-448a-9d19-939ce1958524">See above (ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524)</a></p><p><b>status</b>: final</p><p><b>code</b>: Growth Promotion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#GrowthPromotion)</span></p><p><b>subject</b>: <a href="#Procedure_44aa47fd-8964-5f96-8495-b2bec7f161a8">See above (Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Growth Promotion - Beginning)</span></p><p><b>value</b>: Pass</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Growth Promotion - End)</span></p><p><b>value</b>: Pass</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/GrowthPromotion -->
<reference
value="ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="GrowthPromotion"/>
<display value="Growth Promotion"/>
</coding>
</code>
<subject>
<!-- Procedure/procedure-drug-pq-ex1 -->
<reference value="Procedure/44aa47fd-8964-5f96-8495-b2bec7f161a8"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Growth Promotion - Beginning"/>
<display value="Growth Promotion - Beginning"/>
</coding>
</code>
<valueString value="Pass"/>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Growth Promotion - End"/>
<display value="Growth Promotion - End"/>
</coding>
</code>
<valueString value="Pass"/>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64aa47fd-8964-5f98-6495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- growthPromotion2 -->
<id value="64aa47fd-8964-5f98-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="64aa47fd-8964-5f98-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "64aa47fd-8964-5f98-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64515b3c-5134-448a-9d19-939ce1958524">See above (ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524)</a></p><p><b>status</b>: final</p><p><b>code</b>: Growth Promotion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#GrowthPromotion)</span></p><p><b>subject</b>: <a href="#Procedure_44aa47fd-8964-5f96-6495-b2bec7f162a8">See above (Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Growth Promotion - Beginning)</span></p><p><b>value</b>: Pass</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Growth Promotion - End)</span></p><p><b>value</b>: Pass</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/GrowthPromotion -->
<reference
value="ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="GrowthPromotion"/>
<display value="Growth Promotion"/>
</coding>
</code>
<subject>
<!-- Procedure/procedure-run-2 -->
<reference value="Procedure/44aa47fd-8964-5f96-6495-b2bec7f162a8"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Growth Promotion - Beginning"/>
<display value="Growth Promotion - Beginning"/>
</coding>
</code>
<valueString value="Pass"/>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Growth Promotion - End"/>
<display value="Growth Promotion - End"/>
</coding>
</code>
<valueString value="Pass"/>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:74aa47fd-8964-5f99-7495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- growthPromotion3 -->
<id value="74aa47fd-8964-5f99-7495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="74aa47fd-8964-5f99-7495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "74aa47fd-8964-5f99-7495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64515b3c-5134-448a-9d19-939ce1958524">See above (ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524)</a></p><p><b>status</b>: final</p><p><b>code</b>: Growth Promotion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#GrowthPromotion)</span></p><p><b>subject</b>: <a href="#Procedure_44aa47fd-8964-5f96-6495-b2bec7f163a8">See above (Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Growth Promotion - Beginning)</span></p><p><b>value</b>: Pass</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Growth Promotion - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Growth Promotion - End)</span></p><p><b>value</b>: Fail</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/GrowthPromotion -->
<reference
value="ObservationDefinition/64515b3c-5134-448a-9d19-939ce1958524"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="GrowthPromotion"/>
<display value="Growth Promotion"/>
</coding>
</code>
<subject>
<!-- Procedure/procedure-run-3 -->
<reference value="Procedure/44aa47fd-8964-5f96-6495-b2bec7f163a8"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Growth Promotion - Beginning"/>
<display value="Growth Promotion - Beginning"/>
</coding>
</code>
<valueString value="Pass"/>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Growth Promotion - End"/>
<display value="Growth Promotion - End"/>
</coding>
</code>
<valueString value="Fail"/>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-5f96-8495-b2bec7f161a8"/>
<resource>
<Procedure>
<!-- procedure-drug-pq-ex1 -->
<id value="44aa47fd-8964-5f96-8495-b2bec7f161a8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Procedure</b><a name="44aa47fd-8964-5f96-8495-b2bec7f161a8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "44aa47fd-8964-5f96-8495-b2bec7f161a8" </p></div><p><b>identifier</b>: id: Run 1</p><p><b>status</b>: completed</p><p><b>code</b>: Media Challenge Run <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#MediaChallengeRun)</span></p><p><b>subject</b>: <span>: Drug product</span></p></div>
</text>
<!-- <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Procedure-drug-pq"/>
</meta> -->
<identifier>
<value value="Run 1"/>
</identifier>
<status value="completed"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="MediaChallengeRun"/>
<display value="Media Challenge Run"/>
</coding>
</code>
<!-- only needed to suppress IG warning -->
<subject>
<extension
url="http://hl7.org/fhir/StructureDefinition/alternate-reference">
<valueReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
<display value="Drug product"/>
</subject>
</Procedure>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-5f96-6495-b2bec7f162a8"/>
<resource>
<Procedure>
<!-- procedure-run-2 -->
<id value="44aa47fd-8964-5f96-6495-b2bec7f162a8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Procedure</b><a name="44aa47fd-8964-5f96-6495-b2bec7f162a8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "44aa47fd-8964-5f96-6495-b2bec7f162a8" </p></div><p><b>identifier</b>: id: Run 2</p><p><b>status</b>: completed</p><p><b>code</b>: Media Challenge Run <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#MediaChallengeRun)</span></p><p><b>subject</b>: <span>: Drug product</span></p></div>
</text>
<identifier>
<value value="Run 2"/>
</identifier>
<status value="completed"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="MediaChallengeRun"/>
<display value="Media Challenge Run"/>
</coding>
</code>
<!-- only needed to suppress IG warning -->
<subject>
<extension
url="http://hl7.org/fhir/StructureDefinition/alternate-reference">
<valueReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
<display value="Drug product"/>
</subject>
</Procedure>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-5f96-6495-b2bec7f163a8"/>
<resource>
<Procedure>
<!-- procedure-run-3 -->
<id value="44aa47fd-8964-5f96-6495-b2bec7f163a8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Procedure</b><a name="44aa47fd-8964-5f96-6495-b2bec7f163a8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "44aa47fd-8964-5f96-6495-b2bec7f163a8" </p></div><p><b>identifier</b>: id: Run 3</p><p><b>status</b>: completed</p><p><b>code</b>: Media Challenge Run <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#MediaChallengeRun)</span></p><p><b>subject</b>: <span>: Drug product</span></p></div>
</text>
<identifier>
<value value="Run 3"/>
</identifier>
<status value="completed"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="MediaChallengeRun"/>
<display value="Media Challenge Run"/>
</coding>
</code>
<!-- only needed to suppress IG warning -->
<subject>
<extension
url="http://hl7.org/fhir/StructureDefinition/alternate-reference">
<valueReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
<display value="Drug product"/>
</subject>
</Procedure>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-5f96-6495-c2bec7f163a8"/>
<resource>
<Procedure>
<!-- procedure-drug-pq-ex2 -->
<id value="44aa47fd-8964-5f96-6495-c2bec7f163a8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Procedure</b><a name="44aa47fd-8964-5f96-6495-c2bec7f163a8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Procedure "44aa47fd-8964-5f96-6495-c2bec7f163a8" </p></div><p><b>status</b>: completed</p><p><b>code</b>: Lyophilization Homogeneneity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#LyophilizationHomogeneneity)</span></p><p><b>subject</b>: <span>: Drug batch</span></p><h3>Performers</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Actor</b></td></tr><tr><td style="display: none">*</td><td><a name="device-nosubject"> </a><blockquote><p/><p><a name="device-nosubject"> </a></p><h3>Definitions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="#DDLyo1">#DDLyo1</a></td></tr></table></blockquote></td></tr></table><hr/><blockquote><p><b>Generated Narrative: Device #device-nosubject</b><a name="device-nosubject"> </a></p><h3>Definitions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="#DDLyo1">#DDLyo1</a></td></tr></table></blockquote><hr/><blockquote><p><b>Generated Narrative: DeviceDefinition #DDLyo1</b><a name="DDLyo1"> </a></p><p><b>identifier</b>: id: Lyo 1</p></blockquote></div>
</text>
<contained>
<Device>
<id value="device-nosubject"/>
<definition>
<reference>
<reference value="#DDLyo1"/>
</reference>
</definition>
</Device>
</contained>
<contained>
<DeviceDefinition>
<id value="DDLyo1"/>
<identifier>
<value value="Lyo 1"/>
</identifier>
</DeviceDefinition>
</contained>
<status value="completed"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="LyophilizationHomogeneneity"/>
<display value="Lyophilization Homogeneneity"/>
</coding>
</code>
<!-- only needed to suppress IG warning -->
<subject>
<extension
url="http://hl7.org/fhir/StructureDefinition/alternate-reference">
<valueReference>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference
value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</valueReference>
</extension>
<display value="Drug batch"/>
</subject>
<performer>
<actor>
<reference value="#device-nosubject"/>
<display value="Lyo 1"/>
</actor>
</performer>
</Procedure>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-5f96-6495-b2bec7f161e7"/>
<resource>
<Observation>
<!-- postFiltrationFilterIntegrity1 -->
<id value="44aa47fd-8964-5f96-6495-b2bec7f161e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44aa47fd-8964-5f96-6495-b2bec7f161e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44aa47fd-8964-5f96-6495-b2bec7f161e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_75515b3c-5134-448a-9c19-949ce1958434">See above (ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434)</a></p><p><b>status</b>: final</p><p><b>code</b>: Post-filtration Filter Integrity (psig) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Post-filtration Filter Integrity (psig))</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 280 mOsm/kg</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Test Success <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#test-success)</span></td><td>Pass <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/PostFiltrationFilterIntegrity -->
<reference
value="ObservationDefinition/75515b3c-5134-448a-9c19-949ce1958434"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Post-filtration Filter Integrity (psig)"/>
<display value="Post-filtration Filter Integrity (psig)"/>
</coding>
<text value="Post-filtration Filter Integrity (psig)"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="280"/>
<unit value="mOsm/kg"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="test-success"/>
<display value="Test Success"/>
</coding>
</code>
<!-- consider a boolean -->
<valueCodeableConcept>
<text value="Pass"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44aa47fd-8964-4f96-6495-b2bec7f161e7"/>
<resource>
<Observation>
<!-- osmolality1 -->
<id value="44aa47fd-8964-4f96-6495-b2bec7f161e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44aa47fd-8964-4f96-6495-b2bec7f161e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44aa47fd-8964-4f96-6495-b2bec7f161e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3c-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: osmolality <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Osmolality "Osmolality")</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 280 mOsm/kg</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/Osmolality -->
<reference
value="ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Osmolality"/>
<display value="Osmolality"/>
</coding>
<text value="osmolality"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="280"/>
<unit value="mOsm/kg"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54aa47fd-8964-4f96-6495-b2bec7f162e7"/>
<resource>
<Observation>
<!-- osmolality2 -->
<id value="54aa47fd-8964-4f96-6495-b2bec7f162e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54aa47fd-8964-4f96-6495-b2bec7f162e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54aa47fd-8964-4f96-6495-b2bec7f162e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3c-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: osmolality <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Osmolality "Osmolality")</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 285 mOsm/kg</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/Osmolality -->
<reference
value="ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Osmolality"/>
<display value="Osmolality"/>
</coding>
<text value="osmolality"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="285"/>
<unit value="mOsm/kg"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54aa48fd-8964-4f96-6495-b2bec7f163e7"/>
<resource>
<Observation>
<!-- osmolality3 -->
<id value="54aa48fd-8964-4f96-6495-b2bec7f163e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54aa48fd-8964-4f96-6495-b2bec7f163e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54aa48fd-8964-4f96-6495-b2bec7f163e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3c-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: osmolality <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Osmolality "Osmolality")</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 290 mOsm/kg</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/Osmolality -->
<reference
value="ObservationDefinition/64525a3c-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Osmolality"/>
<display value="Osmolality"/>
</coding>
<text value="osmolality"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="290"/>
<unit value="mOsm/kg"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44ba47fd-8964-4f96-6495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- residualMoisture1 -->
<id value="44ba47fd-8964-4f96-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44ba47fd-8964-4f96-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44ba47fd-8964-4f96-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fc27b6d6-9fe2-91c2-2d16-47cb5b295e72">See above (ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72)</a></p><p><b>status</b>: final</p><p><b>code</b>: Residual Moisture (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Residual Moisture "Residual Moisture")</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Residual Moisture - Min <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Residual Moisture - Min)</span></p><p><b>value</b>: 3.1 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Residual Moisture - Max <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Residual Moisture - Max)</span></p><p><b>value</b>: 3.2 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SAMP)</span></p><p><b>value</b>: 2</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/ResidualMoisture -->
<reference
value="ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Residual Moisture"/>
<display value="Residual Moisture"/>
</coding>
<text value="Residual Moisture (%)"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Residual Moisture - Min"/>
<display value="Residual Moisture - Min"/>
</coding>
</code>
<valueQuantity>
<value value="3.1"/>
<unit value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Residual Moisture - Max"/>
<display value="Residual Moisture - Max"/>
</coding>
</code>
<valueQuantity>
<value value="3.2"/>
<unit value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SAMP"/>
<display value="Number of Samples"/>
</coding>
</code>
<valueInteger value="2"/>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44ba47fd-9964-4f96-6495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- residualMoisture2 -->
<id value="44ba47fd-9964-4f96-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44ba47fd-9964-4f96-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44ba47fd-9964-4f96-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fc27b6d6-9fe2-91c2-2d16-47cb5b295e72">See above (ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72)</a></p><p><b>status</b>: final</p><p><b>code</b>: Residual Moisture (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Residual Moisture "Residual Moisture")</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 4.2 %</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Number of Samples <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SAMP)</span></td><td>3</td></tr></table></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/ResidualMoisture -->
<reference
value="ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Residual Moisture"/>
<display value="Residual Moisture"/>
</coding>
<text value="Residual Moisture (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="4.2"/>
<unit value="%"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SAMP"/>
<display value="Number of Samples"/>
</coding>
</code>
<valueInteger value="3"/>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44ba47fd-9964-4f96-6496-b2bec7f161e8"/>
<resource>
<Observation>
<!-- residualMoisture3 -->
<id value="44ba47fd-9964-4f96-6496-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44ba47fd-9964-4f96-6496-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44ba47fd-9964-4f96-6496-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_fc27b6d6-9fe2-91c2-2d16-47cb5b295e72">See above (ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72)</a></p><p><b>status</b>: final</p><p><b>code</b>: Residual Moisture (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Residual Moisture "Residual Moisture")</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 4.4 %</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Number of Samples <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SAMP)</span></td><td>3</td></tr></table></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/ResidualMoisture -->
<reference
value="ObservationDefinition/fc27b6d6-9fe2-91c2-2d16-47cb5b295e72"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Residual Moisture"/>
<display value="Residual Moisture"/>
</coding>
<text value="Residual Moisture (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="4.4"/>
<unit value="%"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SAMP"/>
<display value="Number of Samples"/>
</coding>
</code>
<valueInteger value="3"/>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44ba47fd-8964-4f96-6495-b2bec7f161e7"/>
<resource>
<Observation>
<!-- SE-UHPLCMainPeak1 -->
<id value="44ba47fd-8964-4f96-6495-b2bec7f161e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44ba47fd-8964-4f96-6495-b2bec7f161e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44ba47fd-8964-4f96-6495-b2bec7f161e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLC Main Peak - Beginning)</span></p><p><b>value</b>: 8.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLC Main Peak - End)</span></p><p><b>value</b>: 8.5 %</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCMainPeak -->
<reference
value="ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLC Main Peak - Beginning"/>
<display value="SE-UHPLC Main Peak - Beginning"/>
</coding>
</code>
<valueQuantity>
<value value="8.0"/>
<unit value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLC Main Peak - End"/>
<display value="SE-UHPLC Main Peak - End"/>
</coding>
</code>
<valueQuantity>
<value value="8.5"/>
<unit value="%"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54ca47fd-8964-4f96-6495-b2bec7f162e7"/>
<resource>
<Observation>
<!-- SE-UHPLCMainPeak2 -->
<id value="54ca47fd-8964-4f96-6495-b2bec7f162e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54ca47fd-8964-4f96-6495-b2bec7f162e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54ca47fd-8964-4f96-6495-b2bec7f162e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLC Main Peak - Beginning)</span></p><p><b>value</b>: 9.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLC Main Peak - End)</span></p><p><b>value</b>: 9.5 %</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCMainPeak -->
<reference
value="ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLC Main Peak - Beginning"/>
<display value="SE-UHPLC Main Peak - Beginning"/>
</coding>
</code>
<valueQuantity>
<value value="9.0"/>
<unit value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLC Main Peak - End"/>
<display value="SE-UHPLC Main Peak - End"/>
</coding>
</code>
<valueQuantity>
<value value="9.5"/>
<unit value="%"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54da48fd-8964-4f96-6495-b2bec7f163e7"/>
<resource>
<Observation>
<!-- SE-UHPLCMainPeak3 -->
<id value="54da48fd-8964-4f96-6495-b2bec7f163e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54da48fd-8964-4f96-6495-b2bec7f163e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54da48fd-8964-4f96-6495-b2bec7f163e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLC Main Peak - Beginning)</span></p><p><b>value</b>: 10.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLC Main Peak - End)</span></p><p><b>value</b>: 10.5 %</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCMainPeak -->
<reference
value="ObservationDefinition/64525a3d-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLC Main Peak - Beginning"/>
<display value="SE-UHPLC Main Peak - Beginning"/>
</coding>
</code>
<valueQuantity>
<value value="10.0"/>
<unit value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLC Main Peak - End"/>
<display value="SE-UHPLC Main Peak - End"/>
</coding>
</code>
<valueQuantity>
<value value="10.5"/>
<unit value="%"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44ba47fd-8964-5f96-6495-b2bec7f161e7"/>
<resource>
<Observation>
<!-- SE-UHPLCMainPeakGraph1 -->
<id value="44ba47fd-8964-5f96-6495-b2bec7f161e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44ba47fd-8964-5f96-6495-b2bec7f161e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44ba47fd-8964-5f96-6495-b2bec7f161e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a4d-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (Graph) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: </p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCMainPeakGraph -->
<reference
value="ObservationDefinition/64525a4d-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (Graph)"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueAttachment>
<contentType value="image/png"/>
<data
value="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"/>
</valueAttachment>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54ba47fd-8964-4f96-6495-b2bec7f161e7"/>
<!-- component> these are now done in another non-batch specific obs -->
<resource>
<Observation>
<!-- SE-UHPLCMainPeakLyoph1 -->
<id value="54ba47fd-8964-4f96-6495-b2bec7f161e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54ba47fd-8964-4f96-6495-b2bec7f161e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54ba47fd-8964-4f96-6495-b2bec7f161e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5134-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 91 %</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCMainPeakLyoph -->
<reference
value="ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="91"/>
<unit value="%"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54ba47fd-8964-4f96-6495-b2bec7f161e8"/>
<!-- component> these are now done in another non-batch specific obs -->
<resource>
<Observation>
<!-- SE-UHPLCMainPeakLyoph2 -->
<id value="54ba47fd-8964-4f96-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54ba47fd-8964-4f96-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54ba47fd-8964-4f96-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5134-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 89 %</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCMainPeakLyoph -->
<reference
value="ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="89"/>
<unit value="%"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54ba47fd-8964-4f96-6495-b2bec7f161e9"/>
<!-- component> these are now done in another non-batch specific obs -->
<resource>
<Observation>
<!-- SE-UHPLCMainPeakLyoph3 -->
<id value="54ba47fd-8964-4f96-6495-b2bec7f161e9"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54ba47fd-8964-4f96-6495-b2bec7f161e9"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54ba47fd-8964-4f96-6495-b2bec7f161e9" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5134-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 92 %</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCMainPeakLyoph -->
<reference
value="ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="92"/>
<unit value="%"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54ba48fd-8964-4f96-6495-b2bec7f161e7"/>
<resource>
<Observation>
<!-- SE-UHPLCMainPeakLyophConclusionObs -->
<id value="54ba48fd-8964-4f96-6495-b2bec7f161e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54ba48fd-8964-4f96-6495-b2bec7f161e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54ba48fd-8964-4f96-6495-b2bec7f161e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5134-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak "SE-UHPLC Main Peak")</span></p><p><b>subject</b>: <span>: Product</span></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SAMP)</span></p><p><b>value</b>: 12</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC Main Peak Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCMainPeak - Conclusion "SE-UHPLC Main Peak - Conclusion")</span></p><p><b>value</b>: Pass</p></blockquote></div>
</text>
<!-- not using a separate one, % and conclusion are in one definition -->
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCMainPeakLyoph -->
<reference
value="ObservationDefinition/64525a3d-5134-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak"/>
<display value="SE-UHPLC Main Peak"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<!-- note no value here, because the code us the %. But this obs is really about the conclusion -->
<!-- note no subject here because there is not one specific batch -->
<!-- added only to keep IG happy -->
<subject>
<extension
url="http://hl7.org/fhir/StructureDefinition/data-absent-reason">
<valueCode value="unsupported"/>
</extension>
<display value="Product"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SAMP"/>
<display value="Number of Samples"/>
</coding>
</code>
<valueInteger value="12"/>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCMainPeak - Conclusion"/>
<display value="SE-UHPLC Main Peak - Conclusion"/>
</coding>
<text value="SE-UHPLC Main Peak Conclusion"/>
</code>
<valueString value="Pass"/>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54bb47fd-8964-4f96-6495-b2bec7f161e7"/>
<!-- component> these are now done in another non-batch specific obs -->
<resource>
<Observation>
<!-- SE-UHPLCHMWLyoph1 -->
<id value="54bb47fd-8964-4f96-6495-b2bec7f161e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54bb47fd-8964-4f96-6495-b2bec7f161e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54bb47fd-8964-4f96-6495-b2bec7f161e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5144-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW "SE-UHPLC HMW")</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 88 %</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCHMWLyoph -->
<reference
value="ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW"/>
<display value="SE-UHPLC HMW"/>
</coding>
<text value="SE-UHPLC HMW (%)"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="88"/>
<unit value="%"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54ba47fd-9964-4f96-6495-b2bec7f161e8"/>
<!-- component> these are now done in another non-batch specific obs -->
<resource>
<Observation>
<!-- SE-UHPLCHMWLyoph2 -->
<id value="54ba47fd-9964-4f96-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54ba47fd-9964-4f96-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54ba47fd-9964-4f96-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5144-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW "SE-UHPLC HMW")</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 93 %</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCHMWLyoph -->
<reference
value="ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW"/>
<display value="SE-UHPLC HMW"/>
</coding>
<text value="SE-UHPLC HMW (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="93"/>
<unit value="%"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54ba47fe-8964-4f96-6495-b2bec7f161e9"/>
<!-- component> these are now done in another non-batch specific obs -->
<resource>
<Observation>
<!-- SE-UHPLCHMWLyoph3 -->
<id value="54ba47fe-8964-4f96-6495-b2bec7f161e9"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54ba47fe-8964-4f96-6495-b2bec7f161e9"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54ba47fe-8964-4f96-6495-b2bec7f161e9" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5144-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW "SE-UHPLC HMW")</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><p><b>value</b>: 99 %</p></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCHMWLyoph -->
<reference
value="ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW"/>
<display value="SE-UHPLC HMW"/>
</coding>
<text value="SE-UHPLC HMW (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<valueQuantity>
<value value="99"/>
<unit value="%"/>
</valueQuantity>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:64ba48fd-8964-4f96-6495-b2bec7f161e7"/>
<resource>
<Observation>
<!-- SE-UHPLCHMWLyophConclusionObs -->
<id value="64ba48fd-8964-4f96-6495-b2bec7f161e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="64ba48fd-8964-4f96-6495-b2bec7f161e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "64ba48fd-8964-4f96-6495-b2bec7f161e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a3d-5144-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW "SE-UHPLC HMW")</span></p><p><b>subject</b>: <span>: Product</span></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Number of Samples <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SAMP)</span></p><p><b>value</b>: 9</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW Conclusion <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMWPeak - Conclusion "SE-UHPLC HMW Peak - Conclusion")</span></p><p><b>value</b>: Fail</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCHMWLyoph -->
<reference
value="ObservationDefinition/64525a3d-5144-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW"/>
<display value="SE-UHPLC HMW"/>
</coding>
<text value="SE-UHPLC HMW (%)"/>
</code>
<!-- note no value here, because the code us the %. But this obs is really about the conclusion -->
<!-- not one specific batch -->
<!-- no subject because it applies to all the samples -->
<!-- added only to keep IG happy -->
<subject>
<extension
url="http://hl7.org/fhir/StructureDefinition/data-absent-reason">
<valueCode value="unsupported"/>
</extension>
<display value="Product"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SAMP"/>
<display value="Number of Samples"/>
</coding>
</code>
<valueInteger value="9"/>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMWPeak - Conclusion"/>
<display value="SE-UHPLC HMW Peak - Conclusion"/>
</coding>
<text value="SE-UHPLC HMW Conclusion"/>
</code>
<valueString value="Fail"/>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:44ba47fd-8964-4f97-6495-b2bec7f161e7"/>
<resource>
<Observation>
<!-- SE-UHPLCHMW1 -->
<id value="44ba47fd-8964-4f97-6495-b2bec7f161e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="44ba47fd-8964-4f97-6495-b2bec7f161e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "44ba47fd-8964-4f97-6495-b2bec7f161e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a33-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW "SE-UHPLC HMW")</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW - Beginning)</span></p><p><b>value</b>: 7.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW - End)</span></p><p><b>value</b>: 7.5 %</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCHMW -->
<reference
value="ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW"/>
<display value="SE-UHPLC HMW"/>
</coding>
<text value="SE-UHPLC HMW (%)"/>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW - Beginning"/>
<display value="SE-UHPLC HMW - Beginning"/>
</coding>
</code>
<valueQuantity>
<value value="7.0"/>
<unit value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW - End"/>
<display value="SE-UHPLC HMW - End"/>
</coding>
</code>
<valueQuantity>
<value value="7.5"/>
<unit value="%"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54ca47fd-8964-4f98-6495-b2bec7f162e7"/>
<resource>
<Observation>
<!-- SE-UHPLCHMW2 -->
<id value="54ca47fd-8964-4f98-6495-b2bec7f162e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54ca47fd-8964-4f98-6495-b2bec7f162e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54ca47fd-8964-4f98-6495-b2bec7f162e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a33-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC HMW (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW "SE-UHPLC HMW")</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW - Beginning)</span></p><p><b>value</b>: 8.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW - End)</span></p><p><b>value</b>: 8.5 %</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCHMW -->
<reference
value="ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW"/>
<display value="SE-UHPLC HMW"/>
</coding>
<text value="SE-UHPLC HMW (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW - Beginning"/>
<display value="SE-UHPLC HMW - Beginning"/>
</coding>
</code>
<valueQuantity>
<value value="8.0"/>
<unit value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW - End"/>
<display value="SE-UHPLC HMW - End"/>
</coding>
</code>
<valueQuantity>
<value value="8.5"/>
<unit value="%"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:54da48fd-8964-4f99-6495-b2bec7f163e7"/>
<resource>
<Observation>
<!-- SE-UHPLCHMW3 -->
<id value="54da48fd-8964-4f99-6495-b2bec7f163e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="54da48fd-8964-4f99-6495-b2bec7f163e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "54da48fd-8964-4f99-6495-b2bec7f163e7" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64525a33-5034-448a-9c19-938ce1958424">See above (ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424)</a></p><p><b>status</b>: final</p><p><b>code</b>: SE-UHPLC Main Peak (%) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW "SE-UHPLC HMW")</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - Beginning <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW - Beginning)</span></p><p><b>value</b>: 9.0 %</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: SE-UHPLC HMW - End <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#SE-UHPLCHMW - End)</span></p><p><b>value</b>: 9.5 %</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/SE-UHPLCHMW -->
<reference
value="ObservationDefinition/64525a33-5034-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW"/>
<display value="SE-UHPLC HMW"/>
</coding>
<text value="SE-UHPLC Main Peak (%)"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW - Beginning"/>
<display value="SE-UHPLC HMW - Beginning"/>
</coding>
</code>
<valueQuantity>
<value value="9.0"/>
<unit value="%"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="SE-UHPLCHMW - End"/>
<display value="SE-UHPLC HMW - End"/>
</coding>
</code>
<valueQuantity>
<value value="9.5"/>
<unit value="%"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:55aa47fd-9964-5f97-6495-b2bec7f161e8"/>
<resource>
<Observation>
<!-- fillWeight1 -->
<id value="55aa47fd-9964-5f97-6495-b2bec7f161e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="55aa47fd-9964-5f97-6495-b2bec7f161e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "55aa47fd-9964-5f97-6495-b2bec7f161e8" </p></div><p><b>instantiates</b>: <a href="#ObservationDefinition_64515b3c-5134-448a-9c19-939ce2958524">See above (ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524)</a></p><p><b>status</b>: final</p><p><b>code</b>: Fill Weight <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Fill Weight)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_378fbe5f-5926-3a5c-4c64-5428df877b08">See above (Organization/378fbe5f-5926-3a5c-4c64-5428df877b08)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Fill Weight - Minimum <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Fill Weight - Minimum)</span></p><p><b>value</b>: 9.90 g</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Fill Weight - Maximum <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Fill Weight - Maximum)</span></p><p><b>value</b>: 9.92 g</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Fill Weight - Mean <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#Fill Weight - Mean)</span></p><p><b>value</b>: 9.91 CFU/100 mL</p></blockquote></div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/FillWeight -->
<reference
value="ObservationDefinition/64515b3c-5134-448a-9c19-939ce2958524"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Fill Weight"/>
<display value="Fill Weight"/>
</coding>
</code>
<subject>
<!-- Medication/medication-batch-information-drug-pq-ex1 -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Fill Weight - Minimum"/>
<display value="Fill Weight - Minimum"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="9.90"/>
<unit value="g"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Fill Weight - Maximum"/>
<display value="Fill Weight - Maximum"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="9.92"/>
<unit value="g"/>
</valueQuantity>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="Fill Weight - Mean"/>
<display value="Fill Weight - Mean"/>
</coding>
</code>
<!-- todo UCUM -->
<valueQuantity>
<value value="9.91"/>
<unit value="CFU/100 mL"/>
</valueQuantity>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:45aa47fd-8964-4f96-6495-b2bec7f160f7"/>
<resource>
<Observation>
<!-- fillingHomogeneityConclusion-nosubject -->
<id value="45aa47fd-8964-4f96-6495-b2bec7f160f7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">
<table>
<tr>
<th>Quality Attribute</th>
<th>Justification</th>
<th>Analytical Method</th>
</tr>
<tr>
<td>Quantity</td>
<td>Demonstrates that the drug product content is maintained throughout the filling process</td>
<td>Protein concentration</td>
</tr>
<tr>
<td>Purity</td>
<td>Demonstrates the product quality is not adversely impacted over the duration of the fill through aggregation and / or oxidation</td>
<td>SE-UHPLC</td>
</tr>
<tr>
<td>Subvisible Particles</td>
<td>Quantitatively determines that subvisible particle content is maintained within specification throughout the filling process</td>
<td>Light obscuration</td>
</tr>
</table>
</div>
</text>
<instantiatesReference>
<!-- ObservationDefinition/conclusionHomogeneity -->
<reference
value="ObservationDefinition/22525a3c-5035-448a-9c19-938ce1958424"/>
</instantiatesReference>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="CONC"/>
<display value="Conclusion"/>
</coding>
<text value="Conclusion"/>
</code>
<!-- no subject because it applies to all the samples -->
<!-- added only to keep IG happy -->
<subject>
<extension
url="http://hl7.org/fhir/StructureDefinition/data-absent-reason">
<valueCode value="unsupported"/>
</extension>
<display value="Product"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/378fbe5f-5926-3a5c-4c64-5428df877b08 -->
<reference
value="Organization/378fbe5f-5926-3a5c-4c64-5428df877b08"/>
</performer>
</Observation>
</resource>
</entry>
<!-- MedicinalProductDefinition - the main resource in any product scenario -->
<entry>
<fullUrl value="urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
<!-- Section 1.1 - DP Identification -->
<resource>
<MedicinalProductDefinition>
<!-- medicinalproductdefinition-drug-product-pq-ex1 -->
<id value="a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: MedicinalProductDefinition</b><a name="a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicinalProductDefinition "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" </p></div><p><b>description</b>: Textual description of the product</p><p><b>combinedPharmaceuticalDoseForm</b>: Gastro-resistant tablet <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (standardterms.edqm.eu#10225000)</span></p><p><b>route</b>: Oral use <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (standardterms.edqm.eu#20053000)</span></p><blockquote><p><b>name</b></p><p><b>productName</b>: Biocure</p><p><b>type</b>: Proprietary <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-productNameType-local-pq.html">CodeSystem - Product Name Type</a>#Proprietary)</span></p><h3>Parts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Part</b></td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>20mg</td><td>Strength part <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-medicinal-product-name-part-type.html">Product Name Part Type</a>#StrengthPart)</span></td></tr></table></blockquote></div>
</text>
<description value="Textual description of the product"/>
<combinedPharmaceuticalDoseForm>
<coding>
<system value="http://standardterms.edqm.eu"/>
<code value="10225000"/>
<display value="Gastro-resistant tablet"/>
</coding>
</combinedPharmaceuticalDoseForm>
<route>
<coding>
<system value="http://standardterms.edqm.eu"/>
<code value="20053000"/>
<display value="Oral use"/>
</coding>
</route>
<name>
<productName value="Biocure"/>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-productNameType-local-pq"/>
<code value="Proprietary"/>
<display value="Proprietary"/>
</coding>
</type>
<part>
<part value="20mg"/>
<type>
<coding>
<system
value="http://hl7.org/fhir/medicinal-product-name-part-type"/>
<code value="StrengthPart"/>
<display value="Strength part"/>
</coding>
</type>
</part>
</name>
</MedicinalProductDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d6"/>
<resource>
<Ingredient>
<!-- productIngredient -->
<id value="a0694a7a-aafa-4cbe-8135-c788a9a4d3d6"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Ingredient</b><a name="a0694a7a-aafa-4cbe-8135-c788a9a4d3d6"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Ingredient "a0694a7a-aafa-4cbe-8135-c788a9a4d3d6" </p></div><p><b>status</b>: active</p><p><b>for</b>: <a href="#MedicinalProductDefinition_a0694a7a-aafa-4cbe-8135-c788a9a4d3d5">See above (MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5)</a></p><p><b>role</b>: Active <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-ingredient-role.html">Ingredient Role</a>#100000072072)</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_57a9af63-315d-1585-a261-0e337b289390">See above (SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390)</a></td></tr></table></blockquote></div>
</text>
<status value="active"/>
<for>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</for>
<role>
<coding>
<system value="http://hl7.org/fhir/ingredient-role"/>
<code value="100000072072"/>
<display value="Active"/>
</coding>
</role>
<substance>
<code>
<reference>
<!-- SubstanceDefinition/substancedefinition-component-substance-dxpq-ex1 -->
<reference
value="SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"/>
</reference>
</code>
</substance>
</Ingredient>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:57a9af63-315d-1585-a261-0e337b289390"/>
<resource>
<SubstanceDefinition>
<!-- substancedefinition-component-substance-dxpq-ex1 -->
<id value="57a9af63-315d-1585-a261-0e337b289390"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: SubstanceDefinition</b><a name="57a9af63-315d-1585-a261-0e337b289390"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition "57a9af63-315d-1585-a261-0e337b289390" </p></div><p><b>manufacturer</b>: <a href="#Organization_49d2f0c0-4b28-9271-8aaf-2996a8b9739c">See above (Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c)</a></p><h3>Names</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td></tr><tr><td style="display: none">*</td><td>Biocurolol</td></tr></table></div>
</text>
<!-- <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/SubstanceDefinition-component-substance-pq"/>
</meta> -->
<manufacturer>
<!-- Organization/organization-dxpq-ex1 -->
<reference
value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
</manufacturer>
<name>
<name value="Biocurolol"/>
</name>
</SubstanceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
<resource>
<Organization>
<!-- id value="substance-manufacturer"/ -->
<!-- organization-dxpq-ex1 -->
<id value="49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Organization</b><a name="49d2f0c0-4b28-9271-8aaf-2996a8b9739c"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization "49d2f0c0-4b28-9271-8aaf-2996a8b9739c" </p></div><p><b>identifier</b>: id: 3003040516</p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Address</b></td></tr><tr><td style="display: none">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>
</text>
<!-- <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Organization-pq"/>
</meta> -->
<identifier>
<!-- FDA establishment identifier -->
<system value="urn:oid:2.16.840.1.113883.4.82"/>
<value value="3003040516"/>
</identifier>
<name value="AAA Molybdenum Products, Inc."/>
<contact>
<address>
<line value="7233 W 116th Pl"/>
<line value="Ste C"/>
<city value="Broomfield"/>
<state value="Colorado"/>
<postalCode value="80020"/>
<country value="USA"/>
</address>
</contact>
</Organization>
</resource>
</entry>
<!-- manufacturing plan -->
<entry>
<fullUrl value="urn:uuid:bf6b038b-1334-3dd4-a552-65c169e2265a"/>
<!-- another outer action can be the whole thing, if needed -->
<!-- removed the main actions for brevity (see manufacturing example) -->
<resource>
<PlanDefinition>
<!-- manufacturingProcess-subset-unlinked -->
<id value="bf6b038b-1334-3dd4-a552-65c169e2265a"/>
<!-- indicate this is as subset of the resource. In practice it would have it all -->
<meta>
<profile
value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/PlanDefinition-drug-pq"/>
<tag>
<system
value="http://terminology.hl7.org/CodeSystem/v3-ObservationValue"/>
<code value="SUBSETTED"/>
</tag>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: PlanDefinition</b><a name="bf6b038b-1334-3dd4-a552-65c169e2265a"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource PlanDefinition "bf6b038b-1334-3dd4-a552-65c169e2265a" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-PlanDefinition-drug-pq.html">PlanDefinition - Drug PQ</a></p><p style="margin-bottom: 0px">Tag: <span title="{http://terminology.hl7.org/CodeSystem/v3-ObservationValue http://terminology.hl7.org/CodeSystem/v3-ObservationValue}">http://terminology.hl7.org/CodeSystem/v3-ObservationValue</span></p></div><p><b>Extension - History of Process PQ</b>: This can be text about the history</p><p><b>url</b>: <code>http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a</code></p><p><b>title</b>: Process 1.0</p><p><b>type</b>: Workflow Definition <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-plan-definition-type.html">PlanDefinitionType</a>#workflow-definition; <a href="CodeSystem-cs-planType-local-pq.html">CodeSystem - Plan Type</a>#manufacturing-process "Manufacturing Process")</span></p><p><b>status</b>: active</p><p><b>subject</b>: <a href="#MedicinalProductDefinition_a0694a7a-aafa-4cbe-8135-c788a9a4d3d5">See above (MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5)</a></p><p><b>description</b>: Narrative description of manufacturing process (5)</p><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-pH</blockquote><p><b>category</b>: Physical Property <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-testCategory-local-pq.html">CodeSystem - Test Category</a>#C123456)</span></p><p><b>description</b>: Controls - pH <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>priority</b>: Critical <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-goalPriority-local-pq.html">CodeSystem - Goal Priority</a>#critical)</span></p><h3>Targets</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style="display: none">*</td><td>pH must be in range 6.9 to 7.1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#pH "pH")</span></td><td>6.9-7.1 pH</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-water-content</blockquote><p><b>category</b>: Physical Property <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-testCategory-local-pq.html">CodeSystem - Test Category</a>#C123456)</span></p><p><b>description</b>: Controls - Water Content <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>priority</b>: Critical <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-goalPriority-local-pq.html">CodeSystem - Goal Priority</a>#critical)</span></p><h3>Targets</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style="display: none">*</td><td>Under 2% <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#WaterContent "Water content")</span></td><td>?-2</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>goal-control-particle-size</blockquote><p><b>category</b>: Physical Property <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-testCategory-local-pq.html">CodeSystem - Test Category</a>#C123456)</span></p><p><b>description</b>: Controls - Particle Size <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>priority</b>: Critical <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-goalPriority-local-pq.html">CodeSystem - Goal Priority</a>#critical)</span></p><h3>Targets</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style="display: none">*</td><td>Under 200 microns <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#particle-size "Particle Size")</span></td><td>?-200</td></tr></table></blockquote><blockquote><p><b>actor</b></p><h3>Options</h3><table class="grid"><tr><td style="display: none">-</td><td><b>TypeReference</b></td><td><b>Role</b></td></tr><tr><td style="display: none">*</td><td><a href="#DeviceDefinition_82a39a18-91cf-a29d-76c1-a9e8bad9494d">See above (DeviceDefinition/82a39a18-91cf-a29d-76c1-a9e8bad9494d)</a></td><td>Mixing Vessel <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-equipmentClass-local-pq.html">CodeSystem - Equipment Class</a>#mixing-vessel)</span></td></tr></table></blockquote><blockquote><p><b>actor</b></p><h3>Options</h3><table class="grid"><tr><td style="display: none">-</td><td><b>TypeReference</b></td><td><b>Role</b></td></tr><tr><td style="display: none">*</td><td><a href="#DeviceDefinition_82a39a18-91cf-b29d-76c1-a9e8bad9494d">See above (DeviceDefinition/82a39a18-91cf-b29d-76c1-a9e8bad9494d)</a></td><td>Receiving Vessel <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-equipmentClass-local-pq.html">CodeSystem - Equipment Class</a>#receiving-vessel)</span></td></tr></table></blockquote></div>
</text>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-history-of-process-pq">
<valueMarkdown value="This can be text about the history"/>
</extension>
<!-- http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a -->
<url
value="http://example-server.com/fhir/PlanDefinition/bf6b038b-1334-3dd4-a552-65c169e2265a"/>
<title value="Process 1.0"/>
<type>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
<code value="workflow-definition"/>
<display value="Workflow Definition"/>
</coding>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-planType-local-pq"/>
<code value="manufacturing-process"/>
<display value="Manufacturing Process"/>
</coding>
</type>
<status value="active"/>
<subjectReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-pq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</subjectReference>
<description
value="Narrative description of manufacturing process (5)"/>
<goal id="goal-control-pH">
<category>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-testCategory-local-pq"/>
<code value="C123456"/>
<display value="Physical Property"/>
</coding>
</category>
<!-- this is mandatory, even though we don't really want it -->
<description>
<text value="Controls - pH"/>
</description>
<priority>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-local-pq"/>
<code value="critical"/>
<display value="Critical"/>
</coding>
</priority>
<target>
<measure>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="pH"/>
<display value="pH"/>
</coding>
<text value="pH must be in range 6.9 to 7.1"/>
</measure>
<!-- detailString value="can also be a string" -->
<detailRange>
<low>
<value value="6.9"/>
<unit value="pH"/>
</low>
<high>
<value value="7.1"/>
<unit value="pH"/>
</high>
</detailRange>
</target>
</goal>
<goal id="goal-control-water-content">
<category>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-testCategory-local-pq"/>
<code value="C123456"/>
<display value="Physical Property"/>
</coding>
</category>
<!-- this is mandatory, even though we don't really want it -->
<description>
<text value="Controls - Water Content"/>
</description>
<priority>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-local-pq"/>
<code value="critical"/>
<display value="Critical"/>
</coding>
</priority>
<target>
<measure>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="WaterContent"/>
<display value="Water content"/>
</coding>
<text value="Under 2%"/>
</measure>
<!-- detailString value="can also be a string" -->
<detailRange>
<high>
<value value="2"/>
<unit value="%"/>
</high>
</detailRange>
</target>
</goal>
<goal id="goal-control-particle-size">
<category>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-testCategory-local-pq"/>
<code value="C123456"/>
<display value="Physical Property"/>
</coding>
</category>
<description>
<text value="Controls - Particle Size"/>
</description>
<priority>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-goalPriority-local-pq"/>
<code value="critical"/>
<display value="Critical"/>
</coding>
</priority>
<target>
<measure>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="particle-size"/>
<display value="Particle Size"/>
</coding>
<text value="Under 200 microns"/>
</measure>
<!-- detailString value="can also be a string" -->
<detailRange>
<high>
<value value="200"/>
<unit value="microns"/>
</high>
</detailRange>
</target>
</goal>
<actor>
<option>
<typeReference>
<!-- DeviceDefinition/mixing-vessel -->
<reference
value="DeviceDefinition/82a39a18-91cf-a29d-76c1-a9e8bad9494d"/>
</typeReference>
<role>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-equipmentClass-local-pq"/>
<code value="mixing-vessel"/>
<display value="Mixing Vessel"/>
</coding>
</role>
</option>
</actor>
<actor>
<option>
<typeReference>
<!-- DeviceDefinition/receiving-tank -->
<reference
value="DeviceDefinition/82a39a18-91cf-b29d-76c1-a9e8bad9494d"/>
</typeReference>
<role>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-equipmentClass-local-pq"/>
<code value="receiving-vessel"/>
<display value="Receiving Vessel"/>
</coding>
</role>
</option>
</actor>
</PlanDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:82a39a18-91cf-a29d-76c1-a9e8bad9494d"/>
<resource>
<DeviceDefinition>
<!-- mixing-vessel -->
<id value="82a39a18-91cf-a29d-76c1-a9e8bad9494d"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: DeviceDefinition</b><a name="82a39a18-91cf-a29d-76c1-a9e8bad9494d"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DeviceDefinition "82a39a18-91cf-a29d-76c1-a9e8bad9494d" </p></div><h3>DeviceNames</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>Mixing Vessel</td><td>registered-name</td></tr></table><h3>Classifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>Mixing Vessel <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-deviceType-local-pq.html">CodeSystem - Device Type</a>#mixing-vessel)</span></td></tr></table><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Capacity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-deviceProperty-local-pq.html">CodeSystem - Device Property</a>#Capacity)</span></td><td>1000 litres</td></tr></table></div>
</text>
<deviceName>
<name value="Mixing Vessel"/>
<type value="registered-name"/>
</deviceName>
<classification>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceType-local-pq"/>
<code value="mixing-vessel"/>
<display value="Mixing Vessel"/>
</coding>
</type>
</classification>
<property>
<type>
<!-- seems a little different to "maximum capacity -->
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceProperty-local-pq"/>
<code value="Capacity"/>
<display value="Capacity"/>
</coding>
</type>
<valueQuantity>
<value value="1000"/>
<unit value="litres"/>
</valueQuantity>
</property>
</DeviceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:82a39a18-91cf-b29d-76c1-a9e8bad9494d"/>
<resource>
<DeviceDefinition>
<!-- receiving-tank -->
<id value="82a39a18-91cf-b29d-76c1-a9e8bad9494d"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: DeviceDefinition</b><a name="82a39a18-91cf-b29d-76c1-a9e8bad9494d"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DeviceDefinition "82a39a18-91cf-b29d-76c1-a9e8bad9494d" </p></div><h3>DeviceNames</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Name</b></td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>Receiving Tank</td><td>registered-name</td></tr></table><h3>Classifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>Receiving Tank <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-deviceType-local-pq.html">CodeSystem - Device Type</a>#receiving-tank)</span></td></tr></table><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Capacity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-deviceProperty-local-pq.html">CodeSystem - Device Property</a>#Capacity)</span></td><td>1200 litres</td></tr></table></div>
</text>
<deviceName>
<name value="Receiving Tank"/>
<type value="registered-name"/>
</deviceName>
<classification>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceType-local-pq"/>
<code value="receiving-tank"/>
<display value="Receiving Tank"/>
</coding>
</type>
</classification>
<property>
<type>
<!-- seems a little different to "maximum capacity -->
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-deviceProperty-local-pq"/>
<code value="Capacity"/>
<display value="Capacity"/>
</coding>
</type>
<valueQuantity>
<value value="1200"/>
<unit value="litres"/>
</valueQuantity>
</property>
</DeviceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fc078762-81c5-5656-9744-13c7ad1e595b"/>
<resource>
<Substance>
<!-- <id value="actual-batch-substance"/> -->
<!-- substance-dxpq-ex1 -->
<id value="fc078762-81c5-5656-9744-13c7ad1e595b"/>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Substance</b><a name="fc078762-81c5-5656-9744-13c7ad1e595b"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Substance "fc078762-81c5-5656-9744-13c7ad1e595b" </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: <a href="#Organization_49d2f0c0-4b28-9271-8aaf-2996a8b9739c">See above (Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c)</a></p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: id: CAT1</p><p><b>instance</b>: true</p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_57a9af63-315d-1585-a261-0e337b289390">See above (SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390)</a></td></tr></table></div>
</text>
<!-- <meta>
<profile value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Substance-pq"/>
</meta> -->
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="manufacturingDate">
<valueDateTime value="2019-09-07"/>
</extension>
<extension url="batchQuantity">
<valueQuantity>
<value value="5"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension url="batchUtilization">
<valueCodeableConcept>
<coding>
<system
value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
<code value="C133991"/>
<display value="Development"/>
</coding>
</valueCodeableConcept>
</extension>
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/organization-dxpq-ex1 -->
<reference
value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
</valueReference>
</extension>
</extension>
<!-- local extensions -->
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
<valueDateTime value="2019-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq">
<valueDateTime value="2022-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
<valueQuantity>
<value value="4.8"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<identifier>
<value value="CAT1"/>
</identifier>
<instance value="true"/>
<code>
<reference>
<!-- SubstanceDefinition/substancedefinition-component-substance-dxpq-ex1 -->
<reference
value="SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"/>
</reference>
</code>
</Substance>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:cb31d747-2338-88d5-342c-8e9c097e4dad"/>
<resource>
<Substance>
<!-- actual-batch-substance-2 -->
<id value="cb31d747-2338-88d5-342c-8e9c097e4dad"/>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Substance</b><a name="cb31d747-2338-88d5-342c-8e9c097e4dad"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Substance "cb31d747-2338-88d5-342c-8e9c097e4dad" </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: <a href="#Organization_49d2f0c0-4b28-9271-8aaf-2996a8b9739c">See above (Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c)</a></p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: id: SUB2</p><p><b>instance</b>: true</p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_57a9af63-315d-1585-a261-0e337b289390">See above (SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390)</a></td></tr></table></div>
</text>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="manufacturingDate">
<valueDateTime value="2019-09-07"/>
</extension>
<extension url="batchQuantity">
<valueQuantity>
<value value="5"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension url="batchUtilization">
<valueCodeableConcept>
<coding>
<system
value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
<code value="C133991"/>
<display value="Development"/>
</coding>
</valueCodeableConcept>
</extension>
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/organization-dxpq-ex1 -->
<reference
value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
</valueReference>
</extension>
</extension>
<!-- local extensions -->
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
<valueDateTime value="2019-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq">
<valueDateTime value="2022-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
<valueQuantity>
<value value="4.8"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<identifier>
<value value="SUB2"/>
</identifier>
<instance value="true"/>
<code>
<reference>
<!-- SubstanceDefinition/substancedefinition-component-substance-dxpq-ex1 -->
<reference
value="SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"/>
</reference>
</code>
</Substance>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:1551f97b-6f6d-825e-1fb3-44b0b090808c"/>
<resource>
<Substance>
<!-- actual-batch-substance-3 -->
<id value="1551f97b-6f6d-825e-1fb3-44b0b090808c"/>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Substance</b><a name="1551f97b-6f6d-825e-1fb3-44b0b090808c"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Substance "1551f97b-6f6d-825e-1fb3-44b0b090808c" </p></div><blockquote><p><b>Medication Manufacturing Batch</b></p><blockquote><p><b>url</b></p><code>manufacturingDate</code></blockquote><p><b>value</b>: 2019-09-07</p><blockquote><p><b>url</b></p><code>batchQuantity</code></blockquote><p><b>value</b>: 5 kg</p><blockquote><p><b>url</b></p><code>batchUtilization</code></blockquote><p><b>value</b>: Development <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.0.0/CodeSystem-v3-nciThesaurus.html">NCI Thesaurus</a>#C133991)</span></p><blockquote><p><b>url</b></p><code>assignedManufacturer</code></blockquote><p><b>value</b>: <a href="#Organization_49d2f0c0-4b28-9271-8aaf-2996a8b9739c">See above (Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c)</a></p></blockquote><p><b>Extension - Batch Release Date PQ</b>: 2019-09-08</p><p><b>Extension - Batch Retest Date PQ</b>: 2022-09-08</p><p><b>Extension - Actual Yield PQ</b>: 4.8 kg</p><p><b>identifier</b>: id: SUB3</p><p><b>instance</b>: true</p><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_57a9af63-315d-1585-a261-0e337b289390">See above (SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390)</a></td></tr></table></div>
</text>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="manufacturingDate">
<valueDateTime value="2019-09-07"/>
</extension>
<extension url="batchQuantity">
<valueQuantity>
<value value="5"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<extension url="batchUtilization">
<valueCodeableConcept>
<coding>
<system
value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"/>
<code value="C133991"/>
<display value="Development"/>
</coding>
</valueCodeableConcept>
</extension>
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/organization-dxpq-ex1 -->
<reference
value="Organization/49d2f0c0-4b28-9271-8aaf-2996a8b9739c"/>
</valueReference>
</extension>
</extension>
<!-- local extensions -->
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-release-date-pq">
<valueDateTime value="2019-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-batch-retest-date-pq">
<valueDateTime value="2022-09-08"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-actual-yield-pq">
<valueQuantity>
<value value="4.8"/>
<unit value="kg"/>
</valueQuantity>
</extension>
<identifier>
<value value="SUB3"/>
</identifier>
<instance value="true"/>
<code>
<reference>
<!-- SubstanceDefinition/substancedefinition-component-substance-dxpq-ex1 -->
<reference
value="SubstanceDefinition/57a9af63-315d-1585-a261-0e337b289390"/>
</reference>
</code>
</Substance>
</resource>
</entry>
</Bundle>
IG © HL7 International / Biomedical Research and Regulation. Package hl7.fhir.uv.pharm-quality#1.0.0-ballot based on FHIR 5.0.0. Generated 2023-12-18
Links: Table of Contents |
QA Report
| Version History |
|
Propose a change