Pharmaceutical Quality (Industry)
1.0.0-ballot - ballot
Pharmaceutical Quality (Industry)
1.0.0-ballot - ballot
This page is part of the Pharmaceutical Quality (Industry) (v1.0.0-ballot: STU1 Ballot 1) based on FHIR (HL7® FHIR® Standard) v5.0.0. . For a full list of available versions, see the Directory of published versions
<!-- 32P55 Characterization of Impurities -->
<Bundle xmlns="http://hl7.org/fhir">
<id value="bundle-product-impurities-pq-ex1"/>
<meta>
<profile
value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-product-impurities-pq"/>
</meta>
<type value="collection"/>
<entry>
<fullUrl value="urn:uuid:6f4a3311-92c5-2b4a-533e-76341e414c63"/>
<resource>
<DiagnosticReport>
<!-- <id value="studyResultsReport"/> -->
<id value="diagnosticreport-product-impurities"/>
<meta>
<profile
value="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/DiagnosticReport-analysis-drug-pq"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: DiagnosticReport</b><a name="diagnosticreport-product-impurities"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource DiagnosticReport "diagnosticreport-product-impurities" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-DiagnosticReport-analysis-drug-pq.html">DiagnosticReport - Analysis Drug PQ</a></p></div><p><b>identifier</b>: id: ABC1234</p><p><b>status</b>: final</p><p><b>code</b>: Impurities Report <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-reportType-local-pq.html">CodeSystem - Report Type</a>#Impurities Report)</span></p><p><b>effective</b>: 2020-12</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>result</b>: </p><ul><li><a href="#Observation_ab7997fa-7b46-1175-3f01-6f6997f7878a">See above (Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a)</a></li><li><a href="#Observation_4052f28b-64a2-392d-35e4-ec8e912434d2">See above (Observation/4052f28b-64a2-392d-35e4-ec8e912434d2)</a></li><li><a href="#Observation_34ebc51d-8105-0589-3c8d-e7aa6bd0a06c">See above (Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c)</a></li><li><a href="#Observation_2940bf11-05bf-6ce2-3c64-457d0d1f9913">See above (Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913)</a></li><li><a href="#Observation_332b1e76-6f70-2b4e-5d0c-f22a0e042d3e">See above (Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e)</a></li><li><a href="#Observation_f0a13a3b-2e8b-594f-6874-6050511e4c57">See above (Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57)</a></li><li><a href="#Observation_7fe7ccd7-6449-0186-2282-3eeb4cf6a795">See above (Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795)</a></li><li><a href="#Observation_be016630-8754-7414-9014-21e020ad66c6">See above (Observation/be016630-8754-7414-9014-21e020ad66c6)</a></li><li><a href="#Observation_92568f68-78f3-908c-6935-ff5f3d574dd6">See above (Observation/92568f68-78f3-908c-6935-ff5f3d574dd6)</a></li><li><a href="#Observation_7fe7ccd7-6449-0186-2282-3eeb4cf6a796">See above (Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a796)</a></li><li><a href="#Observation_be016630-8754-7414-9014-21e020ad66c7">See above (Observation/be016630-8754-7414-9014-21e020ad66c7)</a></li><li><a href="#Observation_92568f68-78f3-908c-6935-ff5f3d574dd7">See above (Observation/92568f68-78f3-908c-6935-ff5f3d574dd7)</a></li><li><a href="#Observation_a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12">See above (Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12)</a></li><li><a href="#Observation_d8533dcb-03f8-5997-6ccf-4f9b6f7a5745">See above (Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745)</a></li><li><a href="#Observation_7cec19a2-34a7-6b80-3d60-083b2cc64fcb">See above (Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb)</a></li><li><a href="#Observation_27aa47fd-7964-4f96-6495-b2bec7f160e7">See above (Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7)</a></li><li><a href="#Observation_6a78bcde-4781-226c-946e-a4b6915c1899">See above (Observation/6a78bcde-4781-226c-946e-a4b6915c1899)</a></li><li><a href="#Observation_f9f11088-7527-947c-3d3f-e71b32e13c78">See above (Observation/f9f11088-7527-947c-3d3f-e71b32e13c78)</a></li><li><a href="#Observation_27aa47fd-7964-4f96-6495-b2bec7f160e8">See above (Observation/27aa47fd-7964-4f96-6495-b2bec7f160e8)</a></li><li><a href="#Observation_6a78bcde-4781-226c-946e-a4b6915c1890">See above (Observation/6a78bcde-4781-226c-946e-a4b6915c1890)</a></li><li><a href="#Observation_f9f11088-7527-947c-3d3f-e71b32e13c79">See above (Observation/f9f11088-7527-947c-3d3f-e71b32e13c79)</a></li><li><a href="#Observation_27aa47fd-7964-4f96-6495-b2bec7f160e9">See above (Observation/27aa47fd-7964-4f96-6495-b2bec7f160e9)</a></li><li><a href="#Observation_6a78bcde-4781-226c-946e-a4b6915c189b">See above (Observation/6a78bcde-4781-226c-946e-a4b6915c189b)</a></li><li><a href="#Observation_f9f11088-7527-947c-3d3f-e71b32e13c70">See above (Observation/f9f11088-7527-947c-3d3f-e71b32e13c70)</a></li></ul><p><b>conclusion</b>: 1. Elemental Impurities - No elemental impurities are intentionally added during the manufacturing of drug product...</p></div>
</text>
<identifier>
<system value="https://eudract.europa.eu/example/identifier"/>
<value value="ABC1234"/>
</identifier>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-reportType-local-pq"/>
<code value="Impurities Report"/>
<display value="Impurities Report"/>
</coding>
</code>
<effectiveDateTime value="2020-12"/>
<!-- start of impurity test -->
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<result>
<!-- Observation/observationDegradation-impCd -->
<reference
value="Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a"/>
</result>
<result>
<!-- Observation/observationDegradation-impCd-2 -->
<reference
value="Observation/4052f28b-64a2-392d-35e4-ec8e912434d2"/>
</result>
<result>
<!-- Observation/observationDegradation-impCd-3 -->
<reference
value="Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"/>
</result>
<result>
<!-- Observation/observationDegradation-impPb -->
<reference
value="Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913"/>
</result>
<result>
<!-- Observation/observationDegradation-impPb-2 -->
<reference
value="Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"/>
</result>
<result>
<!-- Observation/observationDegradation-impPb-3 -->
<reference
value="Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57"/>
</result>
<result>
<!-- Observation/observationDegradation-impAs -->
<reference
value="Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795"/>
</result>
<result>
<!-- Observation/observationDegradation-impAs-2 -->
<reference
value="Observation/be016630-8754-7414-9014-21e020ad66c6"/>
</result>
<result>
<!-- Observation/observationDegradation-impAs-3 -->
<reference
value="Observation/92568f68-78f3-908c-6935-ff5f3d574dd6"/>
</result>
<result>
<!-- Observation/observationDegradation-impHg -->
<reference
value="Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a796"/>
</result>
<result>
<!-- Observation/observationDegradation-impHg-2 -->
<reference
value="Observation/be016630-8754-7414-9014-21e020ad66c7"/>
</result>
<result>
<!-- Observation/observationDegradation-impHg-3 -->
<reference
value="Observation/92568f68-78f3-908c-6935-ff5f3d574dd7"/>
</result>
<result>
<!-- Observation/observationDegradation-impCo -->
<reference
value="Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"/>
</result>
<result>
<!-- Observation/observationDegradation-impCo-2 -->
<reference
value="Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"/>
</result>
<result>
<!-- Observation/observationDegradation-impCo-3 -->
<reference
value="Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb"/>
</result>
<result>
<!-- Observation/observationDegradation-impV -->
<reference
value="Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7"/>
</result>
<result>
<!-- Observation/observationDegradation-impV-2 -->
<reference
value="Observation/6a78bcde-4781-226c-946e-a4b6915c1899"/>
</result>
<result>
<!-- Observation/observationDegradation-impV-3 -->
<reference
value="Observation/f9f11088-7527-947c-3d3f-e71b32e13c78"/>
</result>
<result>
<!-- Observation/observationDegradation-impNi -->
<reference
value="Observation/27aa47fd-7964-4f96-6495-b2bec7f160e8"/>
</result>
<result>
<!-- Observation/observationDegradation-impNi-2 -->
<reference
value="Observation/6a78bcde-4781-226c-946e-a4b6915c1890"/>
</result>
<result>
<!-- Observation/observationDegradation-impNi-3 -->
<reference
value="Observation/f9f11088-7527-947c-3d3f-e71b32e13c79"/>
</result>
<result>
<!-- Observation/observationDegradation-impCu -->
<reference
value="Observation/27aa47fd-7964-4f96-6495-b2bec7f160e9"/>
</result>
<result>
<!-- Observation/observationDegradation-impCu-2 -->
<reference
value="Observation/6a78bcde-4781-226c-946e-a4b6915c189b"/>
</result>
<result>
<!-- Observation/observationDegradation-impCu-3 -->
<reference
value="Observation/f9f11088-7527-947c-3d3f-e71b32e13c70"/>
</result>
<conclusion
value="1. Elemental Impurities - No elemental impurities are intentionally added during the manufacturing of drug product..."/>
</DiagnosticReport>
</resource>
</entry>
<!-- Section 11 - Stability Study - Results -->
<entry>
<fullUrl value="urn:uuid:339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
<resource>
<Medication>
<!-- medication-actual-batch -->
<id value="339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Medication</b><a name="339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51" </p></div><p><b>code</b>: <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td/><td>33445</td></tr></table></div>
</text>
<code>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
<valueReference>
<!-- todo consider change this be the MID? -->
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-dxpq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
</code>
<batch>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/manufacturer -->
<reference
value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
</valueReference>
</extension>
</extension>
<lotNumber value="33445"/>
</batch>
</Medication>
</resource>
</entry>
<!-- Section 8 - Batch or Lot Information (another batch 2 of 3) -->
<entry>
<fullUrl value="urn:uuid:a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
<resource>
<Medication>
<!-- medication-actual-batch-2 -->
<id value="a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Medication</b><a name="a9dfda53-734b-045f-7ae4-94a6281d53bc"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "a9dfda53-734b-045f-7ae4-94a6281d53bc" </p></div><p><b>code</b>: <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td/><td>33446</td></tr></table></div>
</text>
<code>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
<valueReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-dxpq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
</code>
<batch>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/manufacturer -->
<reference
value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
</valueReference>
</extension>
</extension>
<lotNumber value="33446"/>
</batch>
</Medication>
</resource>
</entry>
<!-- Section 8 - Batch or Lot Information (another batch 3 of 3) -->
<entry>
<fullUrl value="urn:uuid:c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
<resource>
<Medication>
<!-- medication-actual-batch-3 -->
<id value="c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Medication</b><a name="c6f5fadd-62e6-3a01-93d9-b3b182f67d06"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication "c6f5fadd-62e6-3a01-93d9-b3b182f67d06" </p></div><p><b>code</b>: <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Batches</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style="display: none">*</td><td/><td>33447</td></tr></table></div>
</text>
<code>
<extension
url="http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq">
<valueReference>
<!-- MedicinalProductDefinition/medicinalproductdefinition-drug-product-dxpq-ex1 -->
<reference
value="MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
</valueReference>
</extension>
</code>
<batch>
<extension
url="http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch">
<extension url="assignedManufacturer">
<valueReference>
<!-- Organization/manufacturer -->
<reference
value="Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"/>
</valueReference>
</extension>
</extension>
<lotNumber value="33447"/>
</batch>
</Medication>
</resource>
</entry>
<!-- Section 4.1 - Manufacturer -->
<entry>
<fullUrl value="urn:uuid:0102bca4-46c1-a6bf-1025-cd403fee710a"/>
<resource>
<Organization>
<!-- manufacturer -->
<id value="0102bca4-46c1-a6bf-1025-cd403fee710a"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Organization</b><a name="0102bca4-46c1-a6bf-1025-cd403fee710a"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization "0102bca4-46c1-a6bf-1025-cd403fee710a" </p></div><p><b>identifier</b>: id: 3010027650</p><p><b>name</b>: AAA Pharmaceutical, Inc.</p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Address</b></td></tr><tr><td style="display: none">*</td><td>681 Main Street Lumberton New Jersey 08048 USA </td></tr></table></div>
</text>
<identifier>
<!-- FDA establishment identifier -->
<system value="urn:oid:2.16.840.1.113883.4.82"/>
<value value="3010027650"/>
</identifier>
<name value="AAA Pharmaceutical, Inc."/>
<contact>
<address>
<line value="681 Main Street"/>
<city value="Lumberton"/>
<state value="New Jersey"/>
<postalCode value="08048"/>
<country value="USA"/>
</address>
</contact>
</Organization>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:ab7997fa-7b46-1175-3f01-6f6997f7878a"/>
<resource>
<Observation>
<!-- observationDegradation-impCd -->
<id value="ab7997fa-7b46-1175-3f01-6f6997f7878a"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="ab7997fa-7b46-1175-3f01-6f6997f7878a"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "ab7997fa-7b46-1175-3f01-6f6997f7878a" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <5 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cd <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#66586000 "Cadmium (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="5"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="66586000"/>
<display value="Cadmium (substance)"/>
</coding>
<text value="Cd"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:4052f28b-64a2-392d-35e4-ec8e912434d2"/>
<resource>
<Observation>
<!-- observationDegradation-impCd-2 -->
<id value="4052f28b-64a2-392d-35e4-ec8e912434d2"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="4052f28b-64a2-392d-35e4-ec8e912434d2"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "4052f28b-64a2-392d-35e4-ec8e912434d2" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cd <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#66586000 "Cadmium (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="66586000"/>
<display value="Cadmium (substance)"/>
</coding>
<text value="Cd"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"/>
<resource>
<Observation>
<!-- observationDegradation-impCd-3 -->
<id value="34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "34ebc51d-8105-0589-3c8d-e7aa6bd0a06c" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cd <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#66586000 "Cadmium (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="66586000"/>
<display value="Cadmium (substance)"/>
</coding>
<text value="Cd"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:2940bf11-05bf-6ce2-3c64-457d0d1f9913"/>
<resource>
<Observation>
<!-- observationDegradation-impPb -->
<id value="2940bf11-05bf-6ce2-3c64-457d0d1f9913"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="2940bf11-05bf-6ce2-3c64-457d0d1f9913"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "2940bf11-05bf-6ce2-3c64-457d0d1f9913" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Pb <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#88488004 "Lead (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="88488004"/>
<display value="Lead (substance)"/>
</coding>
<text value="Pb"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"/>
<resource>
<Observation>
<!-- observationDegradation-impPb-2 -->
<id value="332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "332b1e76-6f70-2b4e-5d0c-f22a0e042d3e" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Pb <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#88488004 "Lead (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="88488004"/>
<display value="Lead (substance)"/>
</coding>
<text value="Pb"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:f0a13a3b-2e8b-594f-6874-6050511e4c57"/>
<resource>
<Observation>
<!-- observationDegradation-impPb-3 -->
<id value="f0a13a3b-2e8b-594f-6874-6050511e4c57"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="f0a13a3b-2e8b-594f-6874-6050511e4c57"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "f0a13a3b-2e8b-594f-6874-6050511e4c57" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Pb <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#88488004 "Lead (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="88488004"/>
<display value="Lead (substance)"/>
</coding>
<text value="Pb"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:7fe7ccd7-6449-0186-2282-3eeb4cf6a795"/>
<resource>
<Observation>
<!-- observationDegradation-impAs -->
<id value="7fe7ccd7-6449-0186-2282-3eeb4cf6a795"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="7fe7ccd7-6449-0186-2282-3eeb4cf6a795"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "7fe7ccd7-6449-0186-2282-3eeb4cf6a795" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>As <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#47809000 "Arsenic (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="10"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="47809000"/>
<display value="Arsenic (substance)"/>
</coding>
<text value="As"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:be016630-8754-7414-9014-21e020ad66c6"/>
<resource>
<Observation>
<!-- observationDegradation-impAs-2 -->
<id value="be016630-8754-7414-9014-21e020ad66c6"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="be016630-8754-7414-9014-21e020ad66c6"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "be016630-8754-7414-9014-21e020ad66c6" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>As <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#47809000 "Arsenic (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="10"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="47809000"/>
<display value="Arsenic (substance)"/>
</coding>
<text value="As"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:92568f68-78f3-908c-6935-ff5f3d574dd6"/>
<resource>
<Observation>
<!-- observationDegradation-impAs-3 -->
<id value="92568f68-78f3-908c-6935-ff5f3d574dd6"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="92568f68-78f3-908c-6935-ff5f3d574dd6"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "92568f68-78f3-908c-6935-ff5f3d574dd6" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <5 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>As <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#47809000 "Arsenic (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="5"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="47809000"/>
<display value="Arsenic (substance)"/>
</coding>
<text value="As"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:7fe7ccd7-6449-0186-2282-3eeb4cf6a796"/>
<resource>
<Observation>
<!-- observationDegradation-impHg -->
<id value="7fe7ccd7-6449-0186-2282-3eeb4cf6a796"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="7fe7ccd7-6449-0186-2282-3eeb4cf6a796"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "7fe7ccd7-6449-0186-2282-3eeb4cf6a796" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Hg <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#45262002 "Mercury (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="45262002"/>
<display value="Mercury (substance)"/>
</coding>
<text value="Hg"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:be016630-8754-7414-9014-21e020ad66c7"/>
<resource>
<Observation>
<!-- observationDegradation-impHg-2 -->
<id value="be016630-8754-7414-9014-21e020ad66c7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="be016630-8754-7414-9014-21e020ad66c7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "be016630-8754-7414-9014-21e020ad66c7" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Hg <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#45262002 "Mercury (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="10"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="45262002"/>
<display value="Mercury (substance)"/>
</coding>
<text value="Hg"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:92568f68-78f3-908c-6935-ff5f3d574dd7"/>
<resource>
<Observation>
<!-- observationDegradation-impHg-3 -->
<id value="92568f68-78f3-908c-6935-ff5f3d574dd7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="92568f68-78f3-908c-6935-ff5f3d574dd7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "92568f68-78f3-908c-6935-ff5f3d574dd7" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Hg <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#45262002 "Mercury (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="45262002"/>
<display value="Mercury (substance)"/>
</coding>
<text value="Hg"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"/>
<resource>
<Observation>
<!-- observationDegradation-impCo -->
<id value="a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <50 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Co <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#54808007 "Cobalt (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="50"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="54808007"/>
<display value="Cobalt (substance)"/>
</coding>
<text value="Co"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"/>
<resource>
<Observation>
<!-- observationDegradation-impCo-2 -->
<id value="d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "d8533dcb-03f8-5997-6ccf-4f9b6f7a5745" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <50 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Co <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#54808007 "Cobalt (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="50"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="54808007"/>
<display value="Cobalt (substance)"/>
</coding>
<text value="Co"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:7cec19a2-34a7-6b80-3d60-083b2cc64fcb"/>
<resource>
<Observation>
<!-- observationDegradation-impCo-3 -->
<id value="7cec19a2-34a7-6b80-3d60-083b2cc64fcb"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="7cec19a2-34a7-6b80-3d60-083b2cc64fcb"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "7cec19a2-34a7-6b80-3d60-083b2cc64fcb" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <50 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Co <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#54808007 "Cobalt (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="50"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="54808007"/>
<display value="Cobalt (substance)"/>
</coding>
<text value="Co"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:27aa47fd-7964-4f96-6495-b2bec7f160e7"/>
<resource>
<Observation>
<!-- observationDegradation-impV -->
<id value="27aa47fd-7964-4f96-6495-b2bec7f160e7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="27aa47fd-7964-4f96-6495-b2bec7f160e7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "27aa47fd-7964-4f96-6495-b2bec7f160e7" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>V <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#18925001 "Vanadium (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="10"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="18925001"/>
<display value="Vanadium (substance)"/>
</coding>
<text value="V"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:6a78bcde-4781-226c-946e-a4b6915c1899"/>
<resource>
<Observation>
<!-- observationDegradation-impV-2 -->
<id value="6a78bcde-4781-226c-946e-a4b6915c1899"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="6a78bcde-4781-226c-946e-a4b6915c1899"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "6a78bcde-4781-226c-946e-a4b6915c1899" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>V <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#18925001 "Vanadium (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="10"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="18925001"/>
<display value="Vanadium (substance)"/>
</coding>
<text value="V"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:f9f11088-7527-947c-3d3f-e71b32e13c78"/>
<resource>
<Observation>
<!-- observationDegradation-impV-3 -->
<id value="f9f11088-7527-947c-3d3f-e71b32e13c78"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="f9f11088-7527-947c-3d3f-e71b32e13c78"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "f9f11088-7527-947c-3d3f-e71b32e13c78" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>V <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#18925001 "Vanadium (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="10"/>
<comparator value="<"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="18925001"/>
<display value="Vanadium (substance)"/>
</coding>
<text value="V"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:27aa47fd-7964-4f96-6495-b2bec7f160e8"/>
<resource>
<Observation>
<!-- observationDegradation-impNi -->
<id value="27aa47fd-7964-4f96-6495-b2bec7f160e8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="27aa47fd-7964-4f96-6495-b2bec7f160e8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "27aa47fd-7964-4f96-6495-b2bec7f160e8" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Ni <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#33396006 "Nickel (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="33396006"/>
<display value="Nickel (substance)"/>
</coding>
<text value="Ni"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:6a78bcde-4781-226c-946e-a4b6915c1890"/>
<resource>
<Observation>
<!-- observationDegradation-impNi-2 -->
<id value="6a78bcde-4781-226c-946e-a4b6915c1890"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="6a78bcde-4781-226c-946e-a4b6915c1890"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "6a78bcde-4781-226c-946e-a4b6915c1890" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Ni <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#33396006 "Nickel (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="33396006"/>
<display value="Nickel (substance)"/>
</coding>
<text value="Ni"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:f9f11088-7527-947c-3d3f-e71b32e13c79"/>
<resource>
<Observation>
<!-- observationDegradation-impNi-3 -->
<id value="f9f11088-7527-947c-3d3f-e71b32e13c79"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="f9f11088-7527-947c-3d3f-e71b32e13c79"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "f9f11088-7527-947c-3d3f-e71b32e13c79" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Ni <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#33396006 "Nickel (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueString value="ND"/>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="33396006"/>
<display value="Nickel (substance)"/>
</coding>
<text value="Ni"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:27aa47fd-7964-4f96-6495-b2bec7f160e9"/>
<resource>
<Observation>
<!-- observationDegradation-impCu -->
<id value="27aa47fd-7964-4f96-6495-b2bec7f160e9"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="27aa47fd-7964-4f96-6495-b2bec7f160e9"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "27aa47fd-7964-4f96-6495-b2bec7f160e9" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: 250 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cu <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#66925006 "Copper (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch -->
<reference value="Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="250"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="66925006"/>
<display value="Copper (substance)"/>
</coding>
<text value="Cu"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:6a78bcde-4781-226c-946e-a4b6915c189b"/>
<resource>
<Observation>
<!-- observationDegradation-impCu-2 -->
<id value="6a78bcde-4781-226c-946e-a4b6915c189b"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="6a78bcde-4781-226c-946e-a4b6915c189b"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "6a78bcde-4781-226c-946e-a4b6915c189b" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: 223 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cu <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#66925006 "Copper (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-2 -->
<reference value="Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="223"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="66925006"/>
<display value="Copper (substance)"/>
</coding>
<text value="Cu"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:f9f11088-7527-947c-3d3f-e71b32e13c70"/>
<resource>
<Observation>
<!-- observationDegradation-impCu-3 -->
<id value="f9f11088-7527-947c-3d3f-e71b32e13c70"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Observation</b><a name="f9f11088-7527-947c-3d3f-e71b32e13c70"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Observation "f9f11088-7527-947c-3d3f-e71b32e13c70" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href="#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href="#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: 199 ppm<span style="background: LightGoldenRodYellow"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-local-codes-drug-pq.html">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cu <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#66925006 "Copper (substance)")</span></td></tr></table></div>
</text>
<status value="final"/>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="DGP"/>
<display value="Degradation Products"/>
</coding>
<text value="Degradation Products"/>
</code>
<subject>
<!-- Medication/medication-actual-batch-3 -->
<reference value="Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"/>
</subject>
<effectiveDateTime value="2023-01-01T12:00:00Z"/>
<performer>
<!-- Organization/tester -->
<reference
value="Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
</performer>
<valueQuantity>
<value value="199"/>
<unit value="ppm"/>
<system value="http://unitsofmeasure.org"/>
<code value="[ppm]"/>
</valueQuantity>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq"/>
<code value="IMP"/>
<display value="Impurity"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="66925006"/>
<display value="Copper (substance)"/>
</coding>
<text value="Cu"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3"/>
<resource>
<SubstanceDefinition>
<!-- substance-cadmium -->
<id value="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: SubstanceDefinition</b><a name="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3" </p></div><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-substancePropertyType-local-pq.html">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Cadmium (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#66586000)</span></td></tr></table></div>
</text>
<property>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq"/>
<code value="impurityClassificationMCP"/>
<display
value="Impurity Classification - Mutagenic and Carcinogenic Potential"/>
</coding>
</type>
<valueCodeableConcept>
<text value="Class 1"/>
</valueCodeableConcept>
</property>
<code>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="66586000"/>
<display value="Cadmium (substance)"/>
</coding>
</code>
</code>
</SubstanceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4"/>
<resource>
<SubstanceDefinition>
<!-- substance-lead -->
<id value="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: SubstanceDefinition</b><a name="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4" </p></div><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-substancePropertyType-local-pq.html">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Lead (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#88488004)</span></td></tr></table></div>
</text>
<property>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq"/>
<code value="impurityClassificationMCP"/>
<display
value="Impurity Classification - Mutagenic and Carcinogenic Potential"/>
</coding>
</type>
<valueCodeableConcept>
<text value="Class 1"/>
</valueCodeableConcept>
</property>
<code>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="88488004"/>
<display value="Lead (substance)"/>
</coding>
</code>
</code>
</SubstanceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5"/>
<resource>
<SubstanceDefinition>
<!-- substance-arsenic -->
<id value="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: SubstanceDefinition</b><a name="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5" </p></div><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-substancePropertyType-local-pq.html">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Arsenic (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#47809000)</span></td></tr></table></div>
</text>
<property>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq"/>
<code value="impurityClassificationMCP"/>
<display
value="Impurity Classification - Mutagenic and Carcinogenic Potential"/>
</coding>
</type>
<valueCodeableConcept>
<text value="Class 1"/>
</valueCodeableConcept>
</property>
<code>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="47809000"/>
<display value="Arsenic (substance)"/>
</coding>
</code>
</code>
</SubstanceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6"/>
<resource>
<SubstanceDefinition>
<!-- substance-mercury -->
<id value="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: SubstanceDefinition</b><a name="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6" </p></div><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-substancePropertyType-local-pq.html">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Mercury (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#45262002)</span></td></tr></table></div>
</text>
<property>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq"/>
<code value="impurityClassificationMCP"/>
<display
value="Impurity Classification - Mutagenic and Carcinogenic Potential"/>
</coding>
</type>
<valueCodeableConcept>
<text value="Class 1"/>
</valueCodeableConcept>
</property>
<code>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="45262002"/>
<display value="Mercury (substance)"/>
</coding>
</code>
</code>
</SubstanceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7"/>
<resource>
<SubstanceDefinition>
<!-- substance-cobalt -->
<id value="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: SubstanceDefinition</b><a name="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7" </p></div><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-substancePropertyType-local-pq.html">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 2 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Cobalt (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#54808007)</span></td></tr></table></div>
</text>
<property>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq"/>
<code value="impurityClassificationMCP"/>
<display
value="Impurity Classification - Mutagenic and Carcinogenic Potential"/>
</coding>
</type>
<valueCodeableConcept>
<text value="Class 2"/>
</valueCodeableConcept>
</property>
<code>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="54808007"/>
<display value="Cobalt (substance)"/>
</coding>
</code>
</code>
</SubstanceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8"/>
<resource>
<SubstanceDefinition>
<!-- substance-vanadium -->
<id value="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: SubstanceDefinition</b><a name="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8" </p></div><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-substancePropertyType-local-pq.html">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 2 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Vanadium (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#18925001)</span></td></tr></table></div>
</text>
<property>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq"/>
<code value="impurityClassificationMCP"/>
<display
value="Impurity Classification - Mutagenic and Carcinogenic Potential"/>
</coding>
</type>
<valueCodeableConcept>
<text value="Class 2"/>
</valueCodeableConcept>
</property>
<code>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="18925001"/>
<display value="Vanadium (substance)"/>
</coding>
</code>
</code>
</SubstanceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9"/>
<resource>
<SubstanceDefinition>
<!-- substance-nickel -->
<id value="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: SubstanceDefinition</b><a name="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9" </p></div><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-substancePropertyType-local-pq.html">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 2 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Nickel (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#33396006)</span></td></tr></table></div>
</text>
<property>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq"/>
<code value="impurityClassificationMCP"/>
<display
value="Impurity Classification - Mutagenic and Carcinogenic Potential"/>
</coding>
</type>
<valueCodeableConcept>
<text value="Class 2"/>
</valueCodeableConcept>
</property>
<code>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="33396006"/>
<display value="Nickel (substance)"/>
</coding>
</code>
</code>
</SubstanceDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0"/>
<resource>
<SubstanceDefinition>
<!-- substance-copper -->
<id value="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: SubstanceDefinition</b><a name="fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0" </p></div><h3>Properties</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-substancePropertyType-local-pq.html">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 3 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></td></tr></table><h3>Codes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td></tr><tr><td style="display: none">*</td><td>Copper (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#66925006)</span></td></tr></table></div>
</text>
<property>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq"/>
<code value="impurityClassificationMCP"/>
<display
value="Impurity Classification - Mutagenic and Carcinogenic Potential"/>
</coding>
</type>
<valueCodeableConcept>
<text value="Class 3"/>
</valueCodeableConcept>
</property>
<code>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="66925006"/>
<display value="Copper (substance)"/>
</coding>
</code>
</code>
</SubstanceDefinition>
</resource>
</entry>
<!-- MedicinalProductDefinition - the main resource in any product scenario -->
<entry>
<fullUrl value="urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
<!-- Section 1.1 - DP Identification -->
<resource>
<MedicinalProductDefinition>
<!-- medicinalproductdefinition-drug-product-dxpq-ex1 -->
<id value="a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: MedicinalProductDefinition</b><a name="a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicinalProductDefinition "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" </p></div><p><b>description</b>: Textual description of the product</p><p><b>combinedPharmaceuticalDoseForm</b>: Gastro-resistant tablet <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (standardterms.edqm.eu#10225000)</span></p><p><b>route</b>: Oral use <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (standardterms.edqm.eu#20053000)</span></p><h3>Impurities</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Reference</b></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3)</a></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4)</a></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5)</a></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6)</a></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7)</a></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0)</a></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8)</a></td></tr><tr><td style="display: none">*</td><td><a href="#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9)</a></td></tr></table><blockquote><p><b>name</b></p><p><b>productName</b>: Stelbat Tablets, 20mg</p><p><b>type</b>: Proprietary <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-productNameType-local-pq.html">CodeSystem - Product Name Type</a>#Proprietary)</span></p><h3>Parts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Part</b></td><td><b>Type</b></td></tr><tr><td style="display: none">*</td><td>20mg</td><td>Strength part <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-medicinal-product-name-part-type.html">Product Name Part Type</a>#StrengthPart)</span></td></tr></table></blockquote></div>
</text>
<description value="Textual description of the product"/>
<combinedPharmaceuticalDoseForm>
<coding>
<system value="http://standardterms.edqm.eu"/>
<code value="10225000"/>
<display value="Gastro-resistant tablet"/>
</coding>
</combinedPharmaceuticalDoseForm>
<route>
<coding>
<system value="http://standardterms.edqm.eu"/>
<code value="20053000"/>
<display value="Oral use"/>
</coding>
</route>
<impurity>
<reference>
<!-- SubstanceDefinition/substance-cadmium -->
<reference
value="SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3"/>
</reference>
</impurity>
<impurity>
<reference>
<!-- SubstanceDefinition/substance-lead -->
<reference
value="SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4"/>
</reference>
</impurity>
<impurity>
<reference>
<!-- SubstanceDefinition/substance-arsenic -->
<reference
value="SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5"/>
</reference>
</impurity>
<impurity>
<reference>
<!-- SubstanceDefinition/substance-mercury -->
<reference
value="SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6"/>
</reference>
</impurity>
<impurity>
<reference>
<!-- SubstanceDefinition/substance-cobalt -->
<reference
value="SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7"/>
</reference>
</impurity>
<impurity>
<reference>
<!-- SubstanceDefinition/substance-copper -->
<reference
value="SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0"/>
</reference>
</impurity>
<impurity>
<reference>
<!-- SubstanceDefinition/substance-vanadium -->
<reference
value="SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8"/>
</reference>
</impurity>
<impurity>
<reference>
<!-- SubstanceDefinition/substance-nickel -->
<reference
value="SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9"/>
</reference>
</impurity>
<name>
<productName value="Stelbat Tablets, 20mg"/>
<type>
<coding>
<system
value="http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-productNameType-local-pq"/>
<code value="Proprietary"/>
<display value="Proprietary"/>
</coding>
</type>
<part>
<part value="20mg"/>
<type>
<coding>
<system
value="http://hl7.org/fhir/medicinal-product-name-part-type"/>
<code value="StrengthPart"/>
<display value="Strength part"/>
</coding>
</type>
</part>
</name>
</MedicinalProductDefinition>
</resource>
</entry>
<entry>
<fullUrl value="urn:uuid:e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
<resource>
<Organization>
<!-- tester -->
<id value="e3d2bc19-2f10-2b4d-1741-e4135fe612a9"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Organization</b><a name="e3d2bc19-2f10-2b4d-1741-e4135fe612a9"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Organization "e3d2bc19-2f10-2b4d-1741-e4135fe612a9" </p></div><p><b>identifier</b>: id: 3007270600</p><p><b>name</b>: Advanced Analytical Testing Laboratories Inc.</p><h3>Contacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Address</b></td></tr><tr><td style="display: none">*</td><td>30 Silverline Drive North Brunswick New Jersey 08902 USA </td></tr></table></div>
</text>
<!-- could also use assigner here, for #74 -->
<identifier>
<system value="urn:oid:2.16.840.1.113883.4.82"/>
<value value="3007270600"/>
</identifier>
<name value="Advanced Analytical Testing Laboratories Inc."/>
<contact>
<address>
<line value="30 Silverline Drive"/>
<city value="North Brunswick"/>
<state value="New Jersey"/>
<postalCode value="08902"/>
<country value="USA"/>
</address>
</contact>
</Organization>
</resource>
</entry>
</Bundle>
IG © HL7 International / Biomedical Research and Regulation. Package hl7.fhir.uv.pharm-quality#1.0.0-ballot based on FHIR 5.0.0. Generated 2023-12-18
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