Pharmaceutical Quality (Industry)
1.0.0-ballot - ballot
Pharmaceutical Quality (Industry)
1.0.0-ballot - ballot
This page is part of the Pharmaceutical Quality (Industry) (v1.0.0-ballot: STU1 Ballot 1) based on FHIR (HL7® FHIR® Standard) v5.0.0. . For a full list of available versions, see the Directory of published versions
// 32P55 Characterization of Impurities
{
"resourceType" : "Bundle",
"id" : "bundle-product-impurities-pq-ex1",
"meta" : {
"profile" : [
🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-product-impurities-pq"
]
},
"type" : "collection",
"entry" : [
{
"fullUrl" : "urn:uuid:6f4a3311-92c5-2b4a-533e-76341e414c63",
"resource" : {
"resourceType" : "DiagnosticReport",
"id" : "diagnosticreport-product-impurities",
"meta" : // <id value="studyResultsReport"/>
{
"profile" : [
🔗 "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/DiagnosticReport-analysis-drug-pq"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: DiagnosticReport</b><a name=\"diagnosticreport-product-impurities\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DiagnosticReport "diagnosticreport-product-impurities" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-DiagnosticReport-analysis-drug-pq.html\">DiagnosticReport - Analysis Drug PQ</a></p></div><p><b>identifier</b>: id:\u00a0ABC1234</p><p><b>status</b>: final</p><p><b>code</b>: Impurities Report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-reportType-local-pq.html\">CodeSystem - Report Type</a>#Impurities Report)</span></p><p><b>effective</b>: 2020-12</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>result</b>: </p><ul><li><a href=\"#Observation_ab7997fa-7b46-1175-3f01-6f6997f7878a\">See above (Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a)</a></li><li><a href=\"#Observation_4052f28b-64a2-392d-35e4-ec8e912434d2\">See above (Observation/4052f28b-64a2-392d-35e4-ec8e912434d2)</a></li><li><a href=\"#Observation_34ebc51d-8105-0589-3c8d-e7aa6bd0a06c\">See above (Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c)</a></li><li><a href=\"#Observation_2940bf11-05bf-6ce2-3c64-457d0d1f9913\">See above (Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913)</a></li><li><a href=\"#Observation_332b1e76-6f70-2b4e-5d0c-f22a0e042d3e\">See above (Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e)</a></li><li><a href=\"#Observation_f0a13a3b-2e8b-594f-6874-6050511e4c57\">See above (Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57)</a></li><li><a href=\"#Observation_7fe7ccd7-6449-0186-2282-3eeb4cf6a795\">See above (Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795)</a></li><li><a href=\"#Observation_be016630-8754-7414-9014-21e020ad66c6\">See above (Observation/be016630-8754-7414-9014-21e020ad66c6)</a></li><li><a href=\"#Observation_92568f68-78f3-908c-6935-ff5f3d574dd6\">See above (Observation/92568f68-78f3-908c-6935-ff5f3d574dd6)</a></li><li><a href=\"#Observation_7fe7ccd7-6449-0186-2282-3eeb4cf6a796\">See above (Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a796)</a></li><li><a href=\"#Observation_be016630-8754-7414-9014-21e020ad66c7\">See above (Observation/be016630-8754-7414-9014-21e020ad66c7)</a></li><li><a href=\"#Observation_92568f68-78f3-908c-6935-ff5f3d574dd7\">See above (Observation/92568f68-78f3-908c-6935-ff5f3d574dd7)</a></li><li><a href=\"#Observation_a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12\">See above (Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12)</a></li><li><a href=\"#Observation_d8533dcb-03f8-5997-6ccf-4f9b6f7a5745\">See above (Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745)</a></li><li><a href=\"#Observation_7cec19a2-34a7-6b80-3d60-083b2cc64fcb\">See above (Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb)</a></li><li><a href=\"#Observation_27aa47fd-7964-4f96-6495-b2bec7f160e7\">See above (Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7)</a></li><li><a href=\"#Observation_6a78bcde-4781-226c-946e-a4b6915c1899\">See above (Observation/6a78bcde-4781-226c-946e-a4b6915c1899)</a></li><li><a href=\"#Observation_f9f11088-7527-947c-3d3f-e71b32e13c78\">See above (Observation/f9f11088-7527-947c-3d3f-e71b32e13c78)</a></li><li><a href=\"#Observation_27aa47fd-7964-4f96-6495-b2bec7f160e8\">See above (Observation/27aa47fd-7964-4f96-6495-b2bec7f160e8)</a></li><li><a href=\"#Observation_6a78bcde-4781-226c-946e-a4b6915c1890\">See above (Observation/6a78bcde-4781-226c-946e-a4b6915c1890)</a></li><li><a href=\"#Observation_f9f11088-7527-947c-3d3f-e71b32e13c79\">See above (Observation/f9f11088-7527-947c-3d3f-e71b32e13c79)</a></li><li><a href=\"#Observation_27aa47fd-7964-4f96-6495-b2bec7f160e9\">See above (Observation/27aa47fd-7964-4f96-6495-b2bec7f160e9)</a></li><li><a href=\"#Observation_6a78bcde-4781-226c-946e-a4b6915c189b\">See above (Observation/6a78bcde-4781-226c-946e-a4b6915c189b)</a></li><li><a href=\"#Observation_f9f11088-7527-947c-3d3f-e71b32e13c70\">See above (Observation/f9f11088-7527-947c-3d3f-e71b32e13c70)</a></li></ul><p><b>conclusion</b>: 1. Elemental Impurities - No elemental impurities are intentionally added during the manufacturing of drug product...</p></div>"
},
"identifier" : [
{
"system" : "https://eudract.europa.eu/example/identifier",
"value" : "ABC1234"
}
],
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-reportType-local-pq",
"code" : "Impurities Report",
"display" : "Impurities Report"
}
]
},
"effectiveDateTime" : "2020-12",
"performer" : [
// start of impurity test
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"result" : [
// Organization/tester
{
"reference" : "Observation/ab7997fa-7b46-1175-3f01-6f6997f7878a"
},
// Observation/observationDegradation-impCd
{
"reference" : "Observation/4052f28b-64a2-392d-35e4-ec8e912434d2"
},
// Observation/observationDegradation-impCd-2
{
"reference" : "Observation/34ebc51d-8105-0589-3c8d-e7aa6bd0a06c"
},
// Observation/observationDegradation-impCd-3
{
"reference" : "Observation/2940bf11-05bf-6ce2-3c64-457d0d1f9913"
},
// Observation/observationDegradation-impPb
{
"reference" : "Observation/332b1e76-6f70-2b4e-5d0c-f22a0e042d3e"
},
// Observation/observationDegradation-impPb-2
{
"reference" : "Observation/f0a13a3b-2e8b-594f-6874-6050511e4c57"
},
// Observation/observationDegradation-impPb-3
{
"reference" : "Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a795"
},
// Observation/observationDegradation-impAs
{
"reference" : "Observation/be016630-8754-7414-9014-21e020ad66c6"
},
// Observation/observationDegradation-impAs-2
{
"reference" : "Observation/92568f68-78f3-908c-6935-ff5f3d574dd6"
},
// Observation/observationDegradation-impAs-3
{
"reference" : "Observation/7fe7ccd7-6449-0186-2282-3eeb4cf6a796"
},
// Observation/observationDegradation-impHg
{
"reference" : "Observation/be016630-8754-7414-9014-21e020ad66c7"
},
// Observation/observationDegradation-impHg-2
{
"reference" : "Observation/92568f68-78f3-908c-6935-ff5f3d574dd7"
},
// Observation/observationDegradation-impHg-3
{
"reference" : "Observation/a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12"
},
// Observation/observationDegradation-impCo
{
"reference" : "Observation/d8533dcb-03f8-5997-6ccf-4f9b6f7a5745"
},
// Observation/observationDegradation-impCo-2
{
"reference" : "Observation/7cec19a2-34a7-6b80-3d60-083b2cc64fcb"
},
// Observation/observationDegradation-impCo-3
{
"reference" : "Observation/27aa47fd-7964-4f96-6495-b2bec7f160e7"
},
// Observation/observationDegradation-impV
{
"reference" : "Observation/6a78bcde-4781-226c-946e-a4b6915c1899"
},
// Observation/observationDegradation-impV-2
{
"reference" : "Observation/f9f11088-7527-947c-3d3f-e71b32e13c78"
},
// Observation/observationDegradation-impV-3
{
"reference" : "Observation/27aa47fd-7964-4f96-6495-b2bec7f160e8"
},
// Observation/observationDegradation-impNi
{
"reference" : "Observation/6a78bcde-4781-226c-946e-a4b6915c1890"
},
// Observation/observationDegradation-impNi-2
{
"reference" : "Observation/f9f11088-7527-947c-3d3f-e71b32e13c79"
},
// Observation/observationDegradation-impNi-3
{
"reference" : "Observation/27aa47fd-7964-4f96-6495-b2bec7f160e9"
},
// Observation/observationDegradation-impCu
{
"reference" : "Observation/6a78bcde-4781-226c-946e-a4b6915c189b"
},
// Observation/observationDegradation-impCu-2
{
"reference" : "Observation/f9f11088-7527-947c-3d3f-e71b32e13c70"
}
],
"conclusion" : "1. Elemental Impurities - No elemental impurities are intentionally added during the manufacturing of drug product..."
}
},
// Observation/observationDegradation-impCu-3
{
"fullUrl" : "urn:uuid:339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51",
"resource" : {
"resourceType" : "Medication",
"id" : "339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51",
"text" : // medication-actual-batch
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Medication</b><a name=\"339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication "339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51" </p></div><p><b>code</b>: <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>33445</td></tr></table></div>"
},
"code" : {
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
"valueReference" : {
"reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
}
}
]
},
"batch" : // todo consider change this be the MID?
// MedicinalProductDefinition/medicinalproductdefinition-drug-product-dxpq-ex1
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
"extension" : [
{
"url" : "assignedManufacturer",
"valueReference" : {
"reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
}
}
]
}
],
"lotNumber" : "33445"
}
}
},
// Organization/manufacturer
{
"fullUrl" : "urn:uuid:a9dfda53-734b-045f-7ae4-94a6281d53bc",
"resource" : {
"resourceType" : "Medication",
"id" : "a9dfda53-734b-045f-7ae4-94a6281d53bc",
"text" : // medication-actual-batch-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Medication</b><a name=\"a9dfda53-734b-045f-7ae4-94a6281d53bc\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication "a9dfda53-734b-045f-7ae4-94a6281d53bc" </p></div><p><b>code</b>: <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>33446</td></tr></table></div>"
},
"code" : {
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
"valueReference" : {
"reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
}
}
]
},
"batch" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-dxpq-ex1
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
"extension" : [
{
"url" : "assignedManufacturer",
"valueReference" : {
"reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
}
}
]
}
],
"lotNumber" : "33446"
}
}
},
// Organization/manufacturer
{
"fullUrl" : "urn:uuid:c6f5fadd-62e6-3a01-93d9-b3b182f67d06",
"resource" : {
"resourceType" : "Medication",
"id" : "c6f5fadd-62e6-3a01-93d9-b3b182f67d06",
"text" : // medication-actual-batch-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Medication</b><a name=\"c6f5fadd-62e6-3a01-93d9-b3b182f67d06\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication "c6f5fadd-62e6-3a01-93d9-b3b182f67d06" </p></div><p><b>code</b>: <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Extension</b></td><td><b>LotNumber</b></td></tr><tr><td style=\"display: none\">*</td><td/><td>33447</td></tr></table></div>"
},
"code" : {
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-medication-definition-pq",
"valueReference" : {
"reference" : "MedicinalProductDefinition/a0694a7a-aafa-4cbe-8135-c788a9a4d3d5"
}
}
]
},
"batch" : // MedicinalProductDefinition/medicinalproductdefinition-drug-product-dxpq-ex1
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/medication-manufacturingBatch",
"extension" : [
{
"url" : "assignedManufacturer",
"valueReference" : {
"reference" : "Organization/0102bca4-46c1-a6bf-1025-cd403fee710a"
}
}
]
}
],
"lotNumber" : "33447"
}
}
},
// Organization/manufacturer
{
"fullUrl" : "urn:uuid:0102bca4-46c1-a6bf-1025-cd403fee710a",
"resource" : {
"resourceType" : "Organization",
"id" : "0102bca4-46c1-a6bf-1025-cd403fee710a",
"text" : // manufacturer
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Organization</b><a name=\"0102bca4-46c1-a6bf-1025-cd403fee710a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "0102bca4-46c1-a6bf-1025-cd403fee710a" </p></div><p><b>identifier</b>: id:\u00a03010027650</p><p><b>name</b>: AAA Pharmaceutical, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>681 Main Street Lumberton New Jersey 08048 USA </td></tr></table></div>"
},
"identifier" : [
{
"system" : "urn:oid:2.16.840.1.113883.4.82",
"value" : "3010027650"
}
],
"name" : "AAA Pharmaceutical, Inc.",
"contact" : [
// FDA establishment identifier
{
"address" : {
"line" : [
"681 Main Street"
],
"city" : "Lumberton",
"state" : "New Jersey",
"postalCode" : "08048",
"country" : "USA"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:ab7997fa-7b46-1175-3f01-6f6997f7878a",
"resource" : {
"resourceType" : "Observation",
"id" : "ab7997fa-7b46-1175-3f01-6f6997f7878a",
"text" : // observationDegradation-impCd
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"ab7997fa-7b46-1175-3f01-6f6997f7878a\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "ab7997fa-7b46-1175-3f01-6f6997f7878a" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <5 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cd <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#66586000 "Cadmium (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 5,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "66586000",
"display" : "Cadmium (substance)"
}
],
"text" : "Cd"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:4052f28b-64a2-392d-35e4-ec8e912434d2",
"resource" : {
"resourceType" : "Observation",
"id" : "4052f28b-64a2-392d-35e4-ec8e912434d2",
"text" : // observationDegradation-impCd-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"4052f28b-64a2-392d-35e4-ec8e912434d2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "4052f28b-64a2-392d-35e4-ec8e912434d2" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cd <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#66586000 "Cadmium (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "66586000",
"display" : "Cadmium (substance)"
}
],
"text" : "Cd"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:34ebc51d-8105-0589-3c8d-e7aa6bd0a06c",
"resource" : {
"resourceType" : "Observation",
"id" : "34ebc51d-8105-0589-3c8d-e7aa6bd0a06c",
"text" : // observationDegradation-impCd-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"34ebc51d-8105-0589-3c8d-e7aa6bd0a06c\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "34ebc51d-8105-0589-3c8d-e7aa6bd0a06c" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cd <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#66586000 "Cadmium (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "66586000",
"display" : "Cadmium (substance)"
}
],
"text" : "Cd"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:2940bf11-05bf-6ce2-3c64-457d0d1f9913",
"resource" : {
"resourceType" : "Observation",
"id" : "2940bf11-05bf-6ce2-3c64-457d0d1f9913",
"text" : // observationDegradation-impPb
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"2940bf11-05bf-6ce2-3c64-457d0d1f9913\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "2940bf11-05bf-6ce2-3c64-457d0d1f9913" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Pb <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#88488004 "Lead (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "88488004",
"display" : "Lead (substance)"
}
],
"text" : "Pb"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:332b1e76-6f70-2b4e-5d0c-f22a0e042d3e",
"resource" : {
"resourceType" : "Observation",
"id" : "332b1e76-6f70-2b4e-5d0c-f22a0e042d3e",
"text" : // observationDegradation-impPb-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"332b1e76-6f70-2b4e-5d0c-f22a0e042d3e\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "332b1e76-6f70-2b4e-5d0c-f22a0e042d3e" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Pb <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#88488004 "Lead (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "88488004",
"display" : "Lead (substance)"
}
],
"text" : "Pb"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:f0a13a3b-2e8b-594f-6874-6050511e4c57",
"resource" : {
"resourceType" : "Observation",
"id" : "f0a13a3b-2e8b-594f-6874-6050511e4c57",
"text" : // observationDegradation-impPb-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"f0a13a3b-2e8b-594f-6874-6050511e4c57\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "f0a13a3b-2e8b-594f-6874-6050511e4c57" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Pb <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#88488004 "Lead (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "88488004",
"display" : "Lead (substance)"
}
],
"text" : "Pb"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:7fe7ccd7-6449-0186-2282-3eeb4cf6a795",
"resource" : {
"resourceType" : "Observation",
"id" : "7fe7ccd7-6449-0186-2282-3eeb4cf6a795",
"text" : // observationDegradation-impAs
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"7fe7ccd7-6449-0186-2282-3eeb4cf6a795\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "7fe7ccd7-6449-0186-2282-3eeb4cf6a795" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>As <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#47809000 "Arsenic (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 10,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "47809000",
"display" : "Arsenic (substance)"
}
],
"text" : "As"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:be016630-8754-7414-9014-21e020ad66c6",
"resource" : {
"resourceType" : "Observation",
"id" : "be016630-8754-7414-9014-21e020ad66c6",
"text" : // observationDegradation-impAs-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"be016630-8754-7414-9014-21e020ad66c6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "be016630-8754-7414-9014-21e020ad66c6" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>As <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#47809000 "Arsenic (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 10,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "47809000",
"display" : "Arsenic (substance)"
}
],
"text" : "As"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:92568f68-78f3-908c-6935-ff5f3d574dd6",
"resource" : {
"resourceType" : "Observation",
"id" : "92568f68-78f3-908c-6935-ff5f3d574dd6",
"text" : // observationDegradation-impAs-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"92568f68-78f3-908c-6935-ff5f3d574dd6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "92568f68-78f3-908c-6935-ff5f3d574dd6" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <5 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>As <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#47809000 "Arsenic (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 5,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "47809000",
"display" : "Arsenic (substance)"
}
],
"text" : "As"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:7fe7ccd7-6449-0186-2282-3eeb4cf6a796",
"resource" : {
"resourceType" : "Observation",
"id" : "7fe7ccd7-6449-0186-2282-3eeb4cf6a796",
"text" : // observationDegradation-impHg
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"7fe7ccd7-6449-0186-2282-3eeb4cf6a796\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "7fe7ccd7-6449-0186-2282-3eeb4cf6a796" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Hg <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#45262002 "Mercury (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "45262002",
"display" : "Mercury (substance)"
}
],
"text" : "Hg"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:be016630-8754-7414-9014-21e020ad66c7",
"resource" : {
"resourceType" : "Observation",
"id" : "be016630-8754-7414-9014-21e020ad66c7",
"text" : // observationDegradation-impHg-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"be016630-8754-7414-9014-21e020ad66c7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "be016630-8754-7414-9014-21e020ad66c7" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Hg <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#45262002 "Mercury (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 10,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "45262002",
"display" : "Mercury (substance)"
}
],
"text" : "Hg"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:92568f68-78f3-908c-6935-ff5f3d574dd7",
"resource" : {
"resourceType" : "Observation",
"id" : "92568f68-78f3-908c-6935-ff5f3d574dd7",
"text" : // observationDegradation-impHg-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"92568f68-78f3-908c-6935-ff5f3d574dd7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "92568f68-78f3-908c-6935-ff5f3d574dd7" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Hg <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#45262002 "Mercury (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "45262002",
"display" : "Mercury (substance)"
}
],
"text" : "Hg"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12",
"resource" : {
"resourceType" : "Observation",
"id" : "a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12",
"text" : // observationDegradation-impCo
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "a0ba0f6d-8ec0-846a-a70d-f6bca6d01a12" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <50 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Co <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#54808007 "Cobalt (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 50,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "54808007",
"display" : "Cobalt (substance)"
}
],
"text" : "Co"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:d8533dcb-03f8-5997-6ccf-4f9b6f7a5745",
"resource" : {
"resourceType" : "Observation",
"id" : "d8533dcb-03f8-5997-6ccf-4f9b6f7a5745",
"text" : // observationDegradation-impCo-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"d8533dcb-03f8-5997-6ccf-4f9b6f7a5745\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "d8533dcb-03f8-5997-6ccf-4f9b6f7a5745" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <50 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Co <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#54808007 "Cobalt (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 50,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "54808007",
"display" : "Cobalt (substance)"
}
],
"text" : "Co"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:7cec19a2-34a7-6b80-3d60-083b2cc64fcb",
"resource" : {
"resourceType" : "Observation",
"id" : "7cec19a2-34a7-6b80-3d60-083b2cc64fcb",
"text" : // observationDegradation-impCo-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"7cec19a2-34a7-6b80-3d60-083b2cc64fcb\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "7cec19a2-34a7-6b80-3d60-083b2cc64fcb" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <50 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Co <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#54808007 "Cobalt (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 50,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "54808007",
"display" : "Cobalt (substance)"
}
],
"text" : "Co"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:27aa47fd-7964-4f96-6495-b2bec7f160e7",
"resource" : {
"resourceType" : "Observation",
"id" : "27aa47fd-7964-4f96-6495-b2bec7f160e7",
"text" : // observationDegradation-impV
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"27aa47fd-7964-4f96-6495-b2bec7f160e7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "27aa47fd-7964-4f96-6495-b2bec7f160e7" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>V <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#18925001 "Vanadium (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 10,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "18925001",
"display" : "Vanadium (substance)"
}
],
"text" : "V"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:6a78bcde-4781-226c-946e-a4b6915c1899",
"resource" : {
"resourceType" : "Observation",
"id" : "6a78bcde-4781-226c-946e-a4b6915c1899",
"text" : // observationDegradation-impV-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"6a78bcde-4781-226c-946e-a4b6915c1899\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "6a78bcde-4781-226c-946e-a4b6915c1899" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>V <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#18925001 "Vanadium (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 10,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "18925001",
"display" : "Vanadium (substance)"
}
],
"text" : "V"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:f9f11088-7527-947c-3d3f-e71b32e13c78",
"resource" : {
"resourceType" : "Observation",
"id" : "f9f11088-7527-947c-3d3f-e71b32e13c78",
"text" : // observationDegradation-impV-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"f9f11088-7527-947c-3d3f-e71b32e13c78\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "f9f11088-7527-947c-3d3f-e71b32e13c78" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: <10 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>V <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#18925001 "Vanadium (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 10,
"comparator" : "<",
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "18925001",
"display" : "Vanadium (substance)"
}
],
"text" : "V"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:27aa47fd-7964-4f96-6495-b2bec7f160e8",
"resource" : {
"resourceType" : "Observation",
"id" : "27aa47fd-7964-4f96-6495-b2bec7f160e8",
"text" : // observationDegradation-impNi
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"27aa47fd-7964-4f96-6495-b2bec7f160e8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "27aa47fd-7964-4f96-6495-b2bec7f160e8" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Ni <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#33396006 "Nickel (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "33396006",
"display" : "Nickel (substance)"
}
],
"text" : "Ni"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:6a78bcde-4781-226c-946e-a4b6915c1890",
"resource" : {
"resourceType" : "Observation",
"id" : "6a78bcde-4781-226c-946e-a4b6915c1890",
"text" : // observationDegradation-impNi-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"6a78bcde-4781-226c-946e-a4b6915c1890\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "6a78bcde-4781-226c-946e-a4b6915c1890" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Ni <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#33396006 "Nickel (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "33396006",
"display" : "Nickel (substance)"
}
],
"text" : "Ni"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:f9f11088-7527-947c-3d3f-e71b32e13c79",
"resource" : {
"resourceType" : "Observation",
"id" : "f9f11088-7527-947c-3d3f-e71b32e13c79",
"text" : // observationDegradation-impNi-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"f9f11088-7527-947c-3d3f-e71b32e13c79\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "f9f11088-7527-947c-3d3f-e71b32e13c79" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: ND</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Ni <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#33396006 "Nickel (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueString" : "ND",
"component" : [
// Organization/tester
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "33396006",
"display" : "Nickel (substance)"
}
],
"text" : "Ni"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:27aa47fd-7964-4f96-6495-b2bec7f160e9",
"resource" : {
"resourceType" : "Observation",
"id" : "27aa47fd-7964-4f96-6495-b2bec7f160e9",
"text" : // observationDegradation-impCu
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"27aa47fd-7964-4f96-6495-b2bec7f160e9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "27aa47fd-7964-4f96-6495-b2bec7f160e9" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51\">See above (Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: 250 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cu <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#66925006 "Copper (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/339b69fd-4ab1-a1e9-9ea5-1972ba2f6b51"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 250,
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "66925006",
"display" : "Copper (substance)"
}
],
"text" : "Cu"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:6a78bcde-4781-226c-946e-a4b6915c189b",
"resource" : {
"resourceType" : "Observation",
"id" : "6a78bcde-4781-226c-946e-a4b6915c189b",
"text" : // observationDegradation-impCu-2
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"6a78bcde-4781-226c-946e-a4b6915c189b\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "6a78bcde-4781-226c-946e-a4b6915c189b" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_a9dfda53-734b-045f-7ae4-94a6281d53bc\">See above (Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: 223 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cu <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#66925006 "Copper (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/a9dfda53-734b-045f-7ae4-94a6281d53bc"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-2
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 223,
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "66925006",
"display" : "Copper (substance)"
}
],
"text" : "Cu"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:f9f11088-7527-947c-3d3f-e71b32e13c70",
"resource" : {
"resourceType" : "Observation",
"id" : "f9f11088-7527-947c-3d3f-e71b32e13c70",
"text" : // observationDegradation-impCu-3
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"f9f11088-7527-947c-3d3f-e71b32e13c70\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation "f9f11088-7527-947c-3d3f-e71b32e13c70" </p></div><p><b>status</b>: final</p><p><b>code</b>: Degradation Products <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#DGP)</span></p><p><b>subject</b>: <a href=\"#Medication_c6f5fadd-62e6-3a01-93d9-b3b182f67d06\">See above (Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06)</a></p><p><b>effective</b>: 2023-01-01 12:00:00+0000</p><p><b>performer</b>: <a href=\"#Organization_e3d2bc19-2f10-2b4d-1741-e4135fe612a9\">See above (Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9)</a></p><p><b>value</b>: 199 ppm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [ppm] = '[ppm]')</span></p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-local-codes-drug-pq.html\">CodeSystem - Example Local Codes - Drug</a>#IMP)</span></td><td>Cu <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#66925006 "Copper (substance)")</span></td></tr></table></div>"
},
"status" : "final",
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "DGP",
"display" : "Degradation Products"
}
],
"text" : "Degradation Products"
},
"subject" : {
"reference" : "Medication/c6f5fadd-62e6-3a01-93d9-b3b182f67d06"
},
"effectiveDateTime" : "2023-01-01T12:00:00Z",
"performer" : [
// Medication/medication-actual-batch-3
{
"reference" : "Organization/e3d2bc19-2f10-2b4d-1741-e4135fe612a9"
}
],
"valueQuantity" : // Organization/tester
{
"value" : 199,
"unit" : "ppm",
"system" : "http://unitsofmeasure.org",
"code" : "[ppm]"
},
"component" : [
{
"code" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-local-codes-drug-pq",
"code" : "IMP",
"display" : "Impurity"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "66925006",
"display" : "Copper (substance)"
}
],
"text" : "Cu"
}
}
]
}
},
{
"fullUrl" : "urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3",
"resource" : {
"resourceType" : "SubstanceDefinition",
"id" : "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3",
"text" : // substance-cadmium
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3" </p></div><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substancePropertyType-local-pq.html\">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Cadmium (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#66586000)</span></td></tr></table></div>"
},
"property" : [
{
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq",
"code" : "impurityClassificationMCP",
"display" : "Impurity Classification - Mutagenic and Carcinogenic Potential"
}
]
},
"valueCodeableConcept" : {
"text" : "Class 1"
}
}
],
"code" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "66586000",
"display" : "Cadmium (substance)"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4",
"resource" : {
"resourceType" : "SubstanceDefinition",
"id" : "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4",
"text" : // substance-lead
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4" </p></div><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substancePropertyType-local-pq.html\">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Lead (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#88488004)</span></td></tr></table></div>"
},
"property" : [
{
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq",
"code" : "impurityClassificationMCP",
"display" : "Impurity Classification - Mutagenic and Carcinogenic Potential"
}
]
},
"valueCodeableConcept" : {
"text" : "Class 1"
}
}
],
"code" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "88488004",
"display" : "Lead (substance)"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5",
"resource" : {
"resourceType" : "SubstanceDefinition",
"id" : "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5",
"text" : // substance-arsenic
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5" </p></div><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substancePropertyType-local-pq.html\">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Arsenic (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#47809000)</span></td></tr></table></div>"
},
"property" : [
{
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq",
"code" : "impurityClassificationMCP",
"display" : "Impurity Classification - Mutagenic and Carcinogenic Potential"
}
]
},
"valueCodeableConcept" : {
"text" : "Class 1"
}
}
],
"code" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "47809000",
"display" : "Arsenic (substance)"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6",
"resource" : {
"resourceType" : "SubstanceDefinition",
"id" : "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6",
"text" : // substance-mercury
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6" </p></div><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substancePropertyType-local-pq.html\">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Mercury (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#45262002)</span></td></tr></table></div>"
},
"property" : [
{
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq",
"code" : "impurityClassificationMCP",
"display" : "Impurity Classification - Mutagenic and Carcinogenic Potential"
}
]
},
"valueCodeableConcept" : {
"text" : "Class 1"
}
}
],
"code" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "45262002",
"display" : "Mercury (substance)"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7",
"resource" : {
"resourceType" : "SubstanceDefinition",
"id" : "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7",
"text" : // substance-cobalt
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7" </p></div><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substancePropertyType-local-pq.html\">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Cobalt (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#54808007)</span></td></tr></table></div>"
},
"property" : [
{
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq",
"code" : "impurityClassificationMCP",
"display" : "Impurity Classification - Mutagenic and Carcinogenic Potential"
}
]
},
"valueCodeableConcept" : {
"text" : "Class 2"
}
}
],
"code" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "54808007",
"display" : "Cobalt (substance)"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8",
"resource" : {
"resourceType" : "SubstanceDefinition",
"id" : "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8",
"text" : // substance-vanadium
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8" </p></div><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substancePropertyType-local-pq.html\">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Vanadium (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#18925001)</span></td></tr></table></div>"
},
"property" : [
{
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq",
"code" : "impurityClassificationMCP",
"display" : "Impurity Classification - Mutagenic and Carcinogenic Potential"
}
]
},
"valueCodeableConcept" : {
"text" : "Class 2"
}
}
],
"code" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "18925001",
"display" : "Vanadium (substance)"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9",
"resource" : {
"resourceType" : "SubstanceDefinition",
"id" : "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9",
"text" : // substance-nickel
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9" </p></div><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substancePropertyType-local-pq.html\">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Nickel (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#33396006)</span></td></tr></table></div>"
},
"property" : [
{
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq",
"code" : "impurityClassificationMCP",
"display" : "Impurity Classification - Mutagenic and Carcinogenic Potential"
}
]
},
"valueCodeableConcept" : {
"text" : "Class 2"
}
}
],
"code" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "33396006",
"display" : "Nickel (substance)"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0",
"resource" : {
"resourceType" : "SubstanceDefinition",
"id" : "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0",
"text" : // substance-copper
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0" </p></div><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity Classification - Mutagenic and Carcinogenic Potential <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substancePropertyType-local-pq.html\">CodeSystem - Substance Property Type</a>#impurityClassificationMCP)</span></td><td>Class 3 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Copper (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#66925006)</span></td></tr></table></div>"
},
"property" : [
{
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substancePropertyType-local-pq",
"code" : "impurityClassificationMCP",
"display" : "Impurity Classification - Mutagenic and Carcinogenic Potential"
}
]
},
"valueCodeableConcept" : {
"text" : "Class 3"
}
}
],
"code" : [
{
"code" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "66925006",
"display" : "Copper (substance)"
}
]
}
}
]
}
},
{
"fullUrl" : "urn:uuid:a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
"resource" : // Section 1.1 - DP Identification
{
"resourceType" : "MedicinalProductDefinition",
"id" : "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5",
"text" : // medicinalproductdefinition-drug-product-dxpq-ex1
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: MedicinalProductDefinition</b><a name=\"a0694a7a-aafa-4cbe-8135-c788a9a4d3d5\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicinalProductDefinition "a0694a7a-aafa-4cbe-8135-c788a9a4d3d5" </p></div><p><b>description</b>: Textual description of the product</p><p><b>combinedPharmaceuticalDoseForm</b>: Gastro-resistant tablet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#10225000)</span></p><p><b>route</b>: Oral use <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterms.edqm.eu#20053000)</span></p><h3>Impurities</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3\">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3)</a></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4\">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4)</a></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5\">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5)</a></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6\">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6)</a></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7\">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7)</a></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0\">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0)</a></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8\">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8)</a></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"#SubstanceDefinition_fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9\">See above (SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9)</a></td></tr></table><blockquote><p><b>name</b></p><p><b>productName</b>: Stelbat Tablets, 20mg</p><p><b>type</b>: Proprietary <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-productNameType-local-pq.html\">CodeSystem - Product Name Type</a>#Proprietary)</span></p><h3>Parts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Part</b></td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td>20mg</td><td>Strength part <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-medicinal-product-name-part-type.html\">Product Name Part Type</a>#StrengthPart)</span></td></tr></table></blockquote></div>"
},
"description" : "Textual description of the product",
"combinedPharmaceuticalDoseForm" : {
"coding" : [
{
"system" : "http://standardterms.edqm.eu",
"code" : "10225000",
"display" : "Gastro-resistant tablet"
}
]
},
"route" : [
{
"coding" : [
{
"system" : "http://standardterms.edqm.eu",
"code" : "20053000",
"display" : "Oral use"
}
]
}
],
"impurity" : [
{
"reference" : {
"reference" : "SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a3"
}
},
// SubstanceDefinition/substance-cadmium
{
"reference" : {
"reference" : "SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a4"
}
},
// SubstanceDefinition/substance-lead
{
"reference" : {
"reference" : "SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a5"
}
},
// SubstanceDefinition/substance-arsenic
{
"reference" : {
"reference" : "SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a6"
}
},
// SubstanceDefinition/substance-mercury
{
"reference" : {
"reference" : "SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a7"
}
},
// SubstanceDefinition/substance-cobalt
{
"reference" : {
"reference" : "SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a0"
}
},
// SubstanceDefinition/substance-copper
{
"reference" : {
"reference" : "SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a8"
}
},
// SubstanceDefinition/substance-vanadium
{
"reference" : {
"reference" : "SubstanceDefinition/fec78d02-1ec2-48ac-bab3-5ed8b6adf9a9"
}
}
],
"name" : [
// SubstanceDefinition/substance-nickel
{
"productName" : "Stelbat Tablets, 20mg",
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-productNameType-local-pq",
"code" : "Proprietary",
"display" : "Proprietary"
}
]
},
"part" : [
{
"part" : "20mg",
"type" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/medicinal-product-name-part-type",
"code" : "StrengthPart",
"display" : "Strength part"
}
]
}
}
]
}
]
}
},
{
"fullUrl" : "urn:uuid:e3d2bc19-2f10-2b4d-1741-e4135fe612a9",
"resource" : {
"resourceType" : "Organization",
"id" : "e3d2bc19-2f10-2b4d-1741-e4135fe612a9",
"text" : // tester
{
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Organization</b><a name=\"e3d2bc19-2f10-2b4d-1741-e4135fe612a9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "e3d2bc19-2f10-2b4d-1741-e4135fe612a9" </p></div><p><b>identifier</b>: id:\u00a03007270600</p><p><b>name</b>: Advanced Analytical Testing Laboratories Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>30 Silverline Drive North Brunswick New Jersey 08902 USA </td></tr></table></div>"
},
"identifier" : [
// could also use assigner here, for #74
{
"system" : "urn:oid:2.16.840.1.113883.4.82",
"value" : "3007270600"
}
],
"name" : "Advanced Analytical Testing Laboratories Inc.",
"contact" : [
{
"address" : {
"line" : [
"30 Silverline Drive"
],
"city" : "North Brunswick",
"state" : "New Jersey",
"postalCode" : "08902",
"country" : "USA"
}
}
]
}
}
]
}
IG © HL7 International / Biomedical Research and Regulation. Package hl7.fhir.uv.pharm-quality#1.0.0-ballot based on FHIR 5.0.0. Generated 2023-12-18
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