Genomics Reporting Implementation Guide
1.1.0 - Ballot
Genomics Reporting Implementation Guide
1.1.0 - Ballot
This page is part of the Genetic Reporting Implementation Guide (v1.1.0: STU 2 Ballot 1) based on FHIR R4. The current version which supercedes this version is 2.0.0. For a full list of available versions, see the Directory of published versions 
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<Patient>
<text>
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<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p><b>identifier</b>: id: 1007</p><p><b>name</b>: Carrot John Mr </p><p><b>gender</b>: male</p><p><b>birthDate</b>: 1962-12-31</p><p><b>generalPractitioner</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p></div>
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<name>
<given value="Carrot"/>
<given value="John"/>
<given value="Mr"/>
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<method value="POST"/>
<url value="Patient"/>
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<entry>
<fullUrl value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
<resource>
<Practitioner>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p><b>identifier</b>: id: 4654765876</p><p><b>name</b>: Akerman Philip Prof </p><p><b>address</b>: Castro Valley CA </p></div>
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<identifier>
<value value="4654765876"/>
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<name>
<given value="Akerman"/>
<given value="Philip"/>
<given value="Prof"/>
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<address>
<city value="Castro Valley"/>
<state value="CA"/>
</address>
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<request>
<method value="POST"/>
<url value="Practitioner"/>
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<entry>
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<resource>
<Specimen>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/specimen"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p><b>identifier</b>: id: 076e1948-2217-11e9-94d8-12e241dc1f66</p><p><b>status</b>: available</p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><h3>Collections</h3><table class="grid"><tr><td>-</td><td><b>Collector</b></td></tr><tr><td>*</td><td><a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></td></tr></table></div>
</text>
<identifier>
<value value="076e1948-2217-11e9-94d8-12e241dc1f66"/>
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<status value="available"/>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
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<collection>
<collector>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
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</collection>
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<request>
<method value="POST"/>
<url value="Specimen"/>
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</entry>
<entry>
<fullUrl value="urn:uuid:40e85eda-4d31-4bd2-a5a0-c39d63f9824f"/>
<resource>
<Observation>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>code</b>: <span title="Codes: ">Tumor Mutational Burden</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>value</b>: 25.0 somatic variants per megabase of sequenced DNA</p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p></div>
</text>
<status value="final"/>
<code>
<text value="Tumor Mutational Burden"/>
</code>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
</subject>
<performer>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
</performer>
<valueQuantity>
<value value="25.0"/>
<unit value="somatic variants per megabase of sequenced DNA"/>
<system value="http://unitsofmeasure.org"/>
<code value="1/1000000{Base}"/>
</valueQuantity>
<specimen>
<reference value="urn:uuid:a5d6a6a9-4859-480e-85b2-56974fef3b9d"/>
</specimen>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:64b91716-6431-41bd-8fd4-7ac99bebdee9"/>
<resource>
<Observation>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>code</b>: <span title="Codes: ">MSI status</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>value</b>: High</p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p></div>
</text>
<status value="final"/>
<code>
<text value="MSI status"/>
</code>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
</subject>
<performer>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
</performer>
<valueString value="High"/>
<specimen>
<reference value="urn:uuid:a5d6a6a9-4859-480e-85b2-56974fef3b9d"/>
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</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12d"/>
<resource>
<Observation>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://loinc.org 69548-6}">Genetic variant assessment</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA9633-4}">Present</span></p><p><b>method</b>: <span title="Codes: {http://loinc.org LA26398-0}">Sequencing</span></p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 81290-9}">Genomic DNA change (gHGVS)</span></p><p><b>value</b>: <span title="Codes: {http://varnomen.hgvs.org 9:g.5073770G>T}">9:g.5073770G>T</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48005-3}">Amino acid change (pHGVS)</span></p><p><b>value</b>: <span title="Codes: {http://varnomen.hgvs.org p.Val617Phe}">p.Val617Phe</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48006-1}">Amino acid change type</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6698-0}">Missense</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48002-0}">Genomic source class</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6683-2}">Germline</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48018-6}">Gene studied ID</span></p><p><b>value</b>: <span title="Codes: ">JAK2</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
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<system
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<code value="laboratory"/>
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</category>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="69548-6"/>
<display value="Genetic variant assessment"/>
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</code>
<subject>
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<code value="LA9633-4"/>
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<code value="LA26398-0"/>
<display value="Sequencing"/>
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<specimen>
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<code value="81290-9"/>
<display value="Genomic DNA change (gHGVS)"/>
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</code>
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<system value="http://varnomen.hgvs.org"/>
<code value="9:g.5073770G>T"/>
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<component>
<code>
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<system value="http://loinc.org"/>
<code value="48005-3"/>
<display value="Amino acid change (pHGVS)"/>
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</code>
<valueCodeableConcept>
<coding>
<system value="http://varnomen.hgvs.org"/>
<code value="p.Val617Phe"/>
<display value="p.Val617Phe"/>
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<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48006-1"/>
<display value="Amino acid change type"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6698-0"/>
<display value="Missense"/>
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<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48002-0"/>
<display value="Genomic source class"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6683-2"/>
<display value="Germline"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48018-6"/>
<display value="Gene studied ID"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://www.genenames.org/geneId"/>
<display value="JAK2"/>
</coding>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:772de7d7-e1bd-4183-bdb5-cea8eda317cd"/>
<resource>
<Observation>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://loinc.org 69548-6}">Genetic variant assessment</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA9633-4}">Present</span></p><p><b>method</b>: <span title="Codes: {http://loinc.org LA26398-0}">Sequencing</span></p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 81290-9}">Genomic DNA change (gHGVS)</span></p><p><b>value</b>: <span title="Codes: {http://varnomen.hgvs.org 4:g.55972974T>A}">4:g.55972974T>A</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48005-3}">Amino acid change (pHGVS)</span></p><p><b>value</b>: <span title="Codes: {http://varnomen.hgvs.org p.Gln472His}">p.Gln472His</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48006-1}">Amino acid change type</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6698-0}">Missense</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48002-0}">Genomic source class</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6683-2}">Germline</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48018-6}">Gene studied ID</span></p><p><b>value</b>: <span title="Codes: ">KDR</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="69548-6"/>
<display value="Genetic variant assessment"/>
</coding>
</code>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
</subject>
<performer>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
</performer>
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<coding>
<system value="http://loinc.org"/>
<code value="LA9633-4"/>
<display value="Present"/>
</coding>
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<method>
<coding>
<system value="http://loinc.org"/>
<code value="LA26398-0"/>
<display value="Sequencing"/>
</coding>
</method>
<specimen>
<reference value="urn:uuid:a5d6a6a9-4859-480e-85b2-56974fef3b9d"/>
</specimen>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="81290-9"/>
<display value="Genomic DNA change (gHGVS)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://varnomen.hgvs.org"/>
<code value="4:g.55972974T>A"/>
<display value="4:g.55972974T>A"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48005-3"/>
<display value="Amino acid change (pHGVS)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://varnomen.hgvs.org"/>
<code value="p.Gln472His"/>
<display value="p.Gln472His"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48006-1"/>
<display value="Amino acid change type"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6698-0"/>
<display value="Missense"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48002-0"/>
<display value="Genomic source class"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6683-2"/>
<display value="Germline"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48018-6"/>
<display value="Gene studied ID"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://www.genenames.org/geneId"/>
<display value="KDR"/>
</coding>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:b33eb7ec-d83e-49d2-b0f3-729d024ebe01"/>
<resource>
<Observation>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://loinc.org 69548-6}">Genetic variant assessment</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA9633-4}">Present</span></p><p><b>method</b>: <span title="Codes: {http://loinc.org LA26398-0}">Sequencing</span></p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 81290-9}">Genomic DNA change (gHGVS)</span></p><p><b>value</b>: <span title="Codes: {http://varnomen.hgvs.org 2:g.212578380del}">2:g.212578380del</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48006-1}">Amino acid change type</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6698-0}">Missense</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48002-0}">Genomic source class</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6683-2}">Germline</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 48018-6}">Gene studied ID</span></p><p><b>value</b>: <span title="Codes: ">ERBB4</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="69548-6"/>
<display value="Genetic variant assessment"/>
</coding>
</code>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
</subject>
<performer>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
</performer>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA9633-4"/>
<display value="Present"/>
</coding>
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<method>
<coding>
<system value="http://loinc.org"/>
<code value="LA26398-0"/>
<display value="Sequencing"/>
</coding>
</method>
<specimen>
<reference value="urn:uuid:a5d6a6a9-4859-480e-85b2-56974fef3b9d"/>
</specimen>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="81290-9"/>
<display value="Genomic DNA change (gHGVS)"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://varnomen.hgvs.org"/>
<code value="2:g.212578380del"/>
<display value="2:g.212578380del"/>
</coding>
</valueCodeableConcept>
</component>
<!-- component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48005-3"/>
<display value="Amino acid change (pHGVS)"/>
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<valueCodeableConcept>
<coding>
<system value="http://varnomen.hgvs.org"/>
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<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48006-1"/>
<display value="Amino acid change type"/>
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<coding>
<system value="http://loinc.org"/>
<code value="LA6698-0"/>
<display value="Missense"/>
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<code>
<coding>
<system value="http://loinc.org"/>
<code value="48002-0"/>
<display value="Genomic source class"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6683-2"/>
<display value="Germline"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="48018-6"/>
<display value="Gene studied ID"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://www.genenames.org/geneId"/>
<display value="ERBB4"/>
</coding>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:1bf9642d-fd1c-4819-8c5d-44fae4bad524"/>
<resource>
<Observation>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/therapeutic-implication"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes therapeutic-implication}">Therapeutic Implication</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>method</b>: <span title="Codes: {http://loinc.org LA26811-2}">Computational analysis</span></p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p><p><b>derivedFrom</b>: <a href="#urnuuid16fdd5fc-e665-48af-99e4-48d603f3e12d">See above (Observation/null)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 51961-1}">Genetic variation's effect on drug efficacy</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6677-4}">Responsive</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 93044-6}">Level of Evidence</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA30200-2}">Very strong evidence pathogenic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes associated-cancer}">associated-cancer</span></p><p><b>value</b>: <span title="Codes: ">Polycythemia vera (PV)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 51963-7}">Medication assessed</span></p><p><b>value</b>: <span title="Codes: ">Ruxolitinib</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="therapeutic-implication"/>
<display value="Therapeutic Implication"/>
</coding>
</code>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
</subject>
<performer>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
</performer>
<method>
<coding>
<system value="http://loinc.org"/>
<code value="LA26811-2"/>
<display value="Computational analysis"/>
</coding>
</method>
<specimen>
<reference value="urn:uuid:a5d6a6a9-4859-480e-85b2-56974fef3b9d"/>
</specimen>
<derivedFrom>
<reference value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12d"/>
</derivedFrom>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="51961-1"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6677-4"/>
<display value="Responsive"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="93044-6"/>
<display value="Level of Evidence"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA30200-2"/>
<display value="Very strong evidence pathogenic"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="associated-cancer"/>
</coding>
</code>
<valueCodeableConcept>
<text value="Polycythemia vera (PV)"/>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="51963-7"/>
<display value="Medication assessed"/>
</coding>
</code>
<valueCodeableConcept>
<text value="Ruxolitinib"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:1301943b-55db-4adf-8355-3635f7268a1b"/>
<resource>
<Observation>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/therapeutic-implication"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes therapeutic-implication}">Therapeutic Implication</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>method</b>: <span title="Codes: {http://loinc.org LA26811-2}">Computational analysis</span></p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p><p><b>derivedFrom</b>: <a href="#urnuuid16fdd5fc-e665-48af-99e4-48d603f3e12d">See above (Observation/null)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 51961-1}">Genetic variation's effect on drug efficacy</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6677-4}">Responsive</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 93044-6}">Level of Evidence</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA30200-2}">Very strong evidence pathogenic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes associated-cancer}">associated-cancer</span></p><p><b>value</b>: <span title="Codes: ">Polycythemia vera (PV)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 51963-7}">Medication assessed</span></p><p><b>value</b>: <span title="Codes: ">AT9283</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="therapeutic-implication"/>
<display value="Therapeutic Implication"/>
</coding>
</code>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
</subject>
<performer>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
</performer>
<method>
<coding>
<system value="http://loinc.org"/>
<code value="LA26811-2"/>
<display value="Computational analysis"/>
</coding>
</method>
<specimen>
<reference value="urn:uuid:a5d6a6a9-4859-480e-85b2-56974fef3b9d"/>
</specimen>
<derivedFrom>
<reference value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12d"/>
</derivedFrom>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="51961-1"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6677-4"/>
<display value="Responsive"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="93044-6"/>
<display value="Level of Evidence"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA30200-2"/>
<display value="Very strong evidence pathogenic"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="associated-cancer"/>
</coding>
</code>
<valueCodeableConcept>
<text value="Polycythemia vera (PV)"/>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="51963-7"/>
<display value="Medication assessed"/>
</coding>
</code>
<valueCodeableConcept>
<text value="AT9283"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:05713d1c-0df5-46d5-a5a9-2085eef56c20"/>
<resource>
<Observation>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/therapeutic-implication"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes therapeutic-implication}">Therapeutic Implication</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>method</b>: <span title="Codes: {http://loinc.org LA26811-2}">Computational analysis</span></p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p><p><b>derivedFrom</b>: <a href="#urnuuid16fdd5fc-e665-48af-99e4-48d603f3e12d">See above (Observation/null)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 51961-1}">Genetic variation's effect on drug efficacy</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6677-4}">Responsive</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 93044-6}">Level of Evidence</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA30200-2}">Very strong evidence pathogenic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes associated-cancer}">associated-cancer</span></p><p><b>value</b>: <span title="Codes: ">Polycythemia vera (PV)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 51963-7}">Medication assessed</span></p><p><b>value</b>: <span title="Codes: ">SNX-5422</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="therapeutic-implication"/>
<display value="Therapeutic Implication"/>
</coding>
</code>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
</subject>
<performer>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
</performer>
<method>
<coding>
<system value="http://loinc.org"/>
<code value="LA26811-2"/>
<display value="Computational analysis"/>
</coding>
</method>
<specimen>
<reference value="urn:uuid:a5d6a6a9-4859-480e-85b2-56974fef3b9d"/>
</specimen>
<derivedFrom>
<reference value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12d"/>
</derivedFrom>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="51961-1"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6677-4"/>
<display value="Responsive"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="93044-6"/>
<display value="Level of Evidence"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA30200-2"/>
<display value="Very strong evidence pathogenic"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="associated-cancer"/>
</coding>
</code>
<valueCodeableConcept>
<text value="Polycythemia vera (PV)"/>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="51963-7"/>
<display value="Medication assessed"/>
</coding>
</code>
<valueCodeableConcept>
<text value="SNX-5422"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:294f1401-e2eb-4df1-b6d2-09e1b7a6eca4"/>
<resource>
<Observation>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/therapeutic-implication"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes therapeutic-implication}">Therapeutic Implication</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>method</b>: <span title="Codes: {http://loinc.org LA26811-2}">Computational analysis</span></p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p><p><b>derivedFrom</b>: <a href="#urnuuid16fdd5fc-e665-48af-99e4-48d603f3e12d">See above (Observation/null)</a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 51961-1}">Genetic variation's effect on drug efficacy</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA6677-4}">Responsive</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 93044-6}">Level of Evidence</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA30200-2}">Very strong evidence pathogenic</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes associated-cancer}">associated-cancer</span></p><p><b>value</b>: <span title="Codes: ">Polycythemia vera (PV)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 51963-7}">Medication assessed</span></p><p><b>value</b>: <span title="Codes: ">TG02</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="therapeutic-implication"/>
<display value="Therapeutic Implication"/>
</coding>
</code>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
</subject>
<performer>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
</performer>
<method>
<coding>
<system value="http://loinc.org"/>
<code value="LA26811-2"/>
<display value="Computational analysis"/>
</coding>
</method>
<specimen>
<reference value="urn:uuid:a5d6a6a9-4859-480e-85b2-56974fef3b9d"/>
</specimen>
<derivedFrom>
<reference value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12d"/>
</derivedFrom>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="51961-1"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6677-4"/>
<display value="Responsive"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="93044-6"/>
<display value="Level of Evidence"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA30200-2"/>
<display value="Very strong evidence pathogenic"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="associated-cancer"/>
</coding>
</code>
<valueCodeableConcept>
<text value="Polycythemia vera (PV)"/>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="51963-7"/>
<display value="Medication assessed"/>
</coding>
</code>
<valueCodeableConcept>
<text value="TG02"/>
</valueCodeableConcept>
</component>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12f"/>
<resource>
<Observation>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/grouper"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes grouper}">grouper</span></p><p><b>hasMember</b>: </p><ul><li><a href="#urnuuid16fdd5fc-e665-48af-99e4-48d603f3e12d">SNV analysis for JAK2 variant. Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://loinc.org 69548-6}">Genetic variant assessment</span>; <span title="Codes: {http://loinc.org LA9633-4}">Present</span>; <span title="Codes: {http://loinc.org LA26398-0}">Sequencing</span></a></li><li><a href="#urnuuid772de7d7-e1bd-4183-bdb5-cea8eda317cd">SNV analysis for KDR variant. Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://loinc.org 69548-6}">Genetic variant assessment</span>; <span title="Codes: {http://loinc.org LA9633-4}">Present</span>; <span title="Codes: {http://loinc.org LA26398-0}">Sequencing</span></a></li><li><a href="#urnuuidb33eb7ec-d83e-49d2-b0f3-729d024ebe01">SNV analysis for ERBB4 variant. Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://loinc.org 69548-6}">Genetic variant assessment</span>; <span title="Codes: {http://loinc.org LA9633-4}">Present</span>; <span title="Codes: {http://loinc.org LA26398-0}">Sequencing</span></a></li><li><a href="#urnuuid40e85eda-4d31-4bd2-a5a0-c39d63f9824f">TMB value analysis. Generated Summary: <span title="Codes: ">Tumor Mutational Burden</span>; 25.0 somatic variants per megabase of sequenced DNA</a></li><li><a href="#urnuuid64b91716-6431-41bd-8fd4-7ac99bebdee9">MSI status analysis. Generated Summary: <span title="Codes: ">MSI status</span>; value: High</a></li></ul></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="grouper"/>
<display value="grouper"/>
</coding>
</code>
<hasMember>
<reference value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12d"/>
<display value="SNV analysis for JAK2 variant"/>
</hasMember>
<hasMember>
<reference value="urn:uuid:772de7d7-e1bd-4183-bdb5-cea8eda317cd"/>
<display value="SNV analysis for KDR variant"/>
</hasMember>
<hasMember>
<reference value="urn:uuid:b33eb7ec-d83e-49d2-b0f3-729d024ebe01"/>
<display value="SNV analysis for ERBB4 variant"/>
</hasMember>
<hasMember>
<reference value="urn:uuid:40e85eda-4d31-4bd2-a5a0-c39d63f9824f"/>
<display value="TMB value analysis"/>
</hasMember>
<hasMember>
<reference value="urn:uuid:64b91716-6431-41bd-8fd4-7ac99bebdee9"/>
<display value="MSI status analysis"/>
</hasMember>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12e"/>
<resource>
<Observation>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/grouper"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes grouper}">grouper</span></p><p><b>hasMember</b>: </p><ul><li><a href="#urnuuid1bf9642d-fd1c-4819-8c5d-44fae4bad524">Therapy match result 1. Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes therapeutic-implication}">Therapeutic Implication</span>; <span title="Codes: {http://loinc.org LA26811-2}">Computational analysis</span></a></li><li><a href="#urnuuid1301943b-55db-4adf-8355-3635f7268a1b">Therapy match result 2. Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes therapeutic-implication}">Therapeutic Implication</span>; <span title="Codes: {http://loinc.org LA26811-2}">Computational analysis</span></a></li><li><a href="#urnuuid05713d1c-0df5-46d5-a5a9-2085eef56c20">Therapy match result 3. Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes therapeutic-implication}">Therapeutic Implication</span>; <span title="Codes: {http://loinc.org LA26811-2}">Computational analysis</span></a></li><li><a href="#urnuuid294f1401-e2eb-4df1-b6d2-09e1b7a6eca4">Therapy match result 4. Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes therapeutic-implication}">Therapeutic Implication</span>; <span title="Codes: {http://loinc.org LA26811-2}">Computational analysis</span></a></li></ul></div>
</text>
<status value="final"/>
<category>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="grouper"/>
<display value="grouper"/>
</coding>
</code>
<hasMember>
<reference value="urn:uuid:1bf9642d-fd1c-4819-8c5d-44fae4bad524"/>
<display value="Therapy match result 1"/>
</hasMember>
<hasMember>
<reference value="urn:uuid:1301943b-55db-4adf-8355-3635f7268a1b"/>
<display value="Therapy match result 2"/>
</hasMember>
<hasMember>
<reference value="urn:uuid:05713d1c-0df5-46d5-a5a9-2085eef56c20"/>
<display value="Therapy match result 3"/>
</hasMember>
<hasMember>
<reference value="urn:uuid:294f1401-e2eb-4df1-b6d2-09e1b7a6eca4"/>
<display value="Therapy match result 4"/>
</hasMember>
</Observation>
</resource>
<request>
<method value="POST"/>
<url value="Observation"/>
</request>
</entry>
<entry>
<fullUrl value="urn:uuid:ad7a499b-a43b-4cc8-bf46-cac62d9ecae5"/>
<resource>
<DiagnosticReport>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomics-report"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p><b>status</b>: final</p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/v2-0074 GE}">Genetics</span></p><p><b>code</b>: <span title="Codes: {http://loinc.org 81247-9}">Genetic analysis report</span></p><p><b>subject</b>: <a href="#urnuuidd0b4affa-91d6-46d1-af01-b30d9f16ef6d">See above (Patient/null)</a></p><p><b>performer</b>: <a href="#urnuuida48256f8-db37-44e0-a0f6-d7af16c7c9ef">See above (Practitioner/null)</a></p><p><b>specimen</b>: <a href="#urnuuida5d6a6a9-4859-480e-85b2-56974fef3b9d">See above (Specimen/null)</a></p><p><b>result</b>: </p><ul><li><a href="#urnuuid16fdd5fc-e665-48af-99e4-48d603f3e12f">Variants and other biomarker tests. Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes grouper}">grouper</span></a></li><li><a href="#urnuuid16fdd5fc-e665-48af-99e4-48d603f3e12e">Therapy Match Results. Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes grouper}">grouper</span></a></li></ul></div>
</text>
<status value="final"/>
<category>
<coding>
<system value="http://terminology.hl7.org/CodeSystem/v2-0074"/>
<code value="GE"/>
</coding>
</category>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="81247-9"/>
<display value="Master HL7 genetic variant reporting panel"/>
</coding>
<text value="Genetic analysis report"/>
</code>
<subject>
<reference value="urn:uuid:d0b4affa-91d6-46d1-af01-b30d9f16ef6d"/>
</subject>
<performer>
<reference value="urn:uuid:a48256f8-db37-44e0-a0f6-d7af16c7c9ef"/>
</performer>
<specimen>
<reference value="urn:uuid:a5d6a6a9-4859-480e-85b2-56974fef3b9d"/>
</specimen>
<result>
<reference value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12f"/>
<display value="Variants and other biomarker tests"/>
</result>
<result>
<reference value="urn:uuid:16fdd5fc-e665-48af-99e4-48d603f3e12e"/>
<display value="Therapy Match Results"/>
</result>
</DiagnosticReport>
</resource>
<request>
<method value="POST"/>
<url value="DiagnosticReport"/>
</request>
</entry>
</Bundle>
IG © 2019+ HL7 International Clinical Genomics Work Group. Package hl7.fhir.uv.genomics-reporting#1.1.0 based on FHIR 4.0.1. Generated 2021-04-13
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