Pharmaceutical Quality (Industry)
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This page is part of the Pharmaceutical Quality (Industry) (v1.0.0: STU1) based on FHIR (HL7® FHIR® Standard) v5.0.0. This is the current published version. For a full list of available versions, see the Directory of published versions

: Substance Property - example - TTL Representation

Active as of 2024-05-08

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:CodeSystem ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "cs-substance-property-pq-example"] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>This case-sensitive code system <code>http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td style=\"white-space:nowrap\">solubility-water<a name=\"cs-substance-property-pq-example-solubility-water\"> </a></td><td>Solubility purified water</td></tr><tr><td style=\"white-space:nowrap\">water-content<a name=\"cs-substance-property-pq-example-water-content\"> </a></td><td>Water content</td></tr><tr><td style=\"white-space:nowrap\">appearance<a name=\"cs-substance-property-pq-example-appearance\"> </a></td><td>Appearance</td></tr><tr><td style=\"white-space:nowrap\">solubility-water-pheur<a name=\"cs-substance-property-pq-example-solubility-water-pheur\"> </a></td><td>Solubility purified water (PhEur)</td></tr><tr><td style=\"white-space:nowrap\">solubility-acetone-pheur<a name=\"cs-substance-property-pq-example-solubility-acetone-pheur\"> </a></td><td>Solubility Acetone (PhEur)</td></tr><tr><td style=\"white-space:nowrap\">solubility-ethanol-pheur<a name=\"cs-substance-property-pq-example-solubility-ethanol-pheur\"> </a></td><td>Solubility Ethanol (PhEur)</td></tr><tr><td style=\"white-space:nowrap\">solubility-aq-water-2h-approx<a name=\"cs-substance-property-pq-example-solubility-aq-water-2h-approx\"> </a></td><td>Solubility at saturation in Purifed Water after 2 hours (approx)</td></tr><tr><td style=\"white-space:nowrap\">solubility-aq-glucose-2h-approx<a name=\"cs-substance-property-pq-example-solubility-aq-glucose-2h-approx\"> </a></td><td>Solubility at saturation in Glucose (5%) after 2 hours (approx)</td></tr><tr><td style=\"white-space:nowrap\">pH<a name=\"cs-substance-property-pq-example-pH\"> </a></td><td>pH</td></tr><tr><td style=\"white-space:nowrap\">solubility-usp-ph<a name=\"cs-substance-property-pq-example-solubility-usp-ph\"> </a></td><td>Solubility as a function of pH in USP buffers</td></tr><tr><td style=\"white-space:nowrap\">concentration<a name=\"cs-substance-property-pq-example-concentration\"> </a></td><td>Concentration</td></tr><tr><td style=\"white-space:nowrap\">temperature<a name=\"cs-substance-property-pq-example-temperature\"> </a></td><td>Temperature</td></tr><tr><td style=\"white-space:nowrap\">ph-aq<a name=\"cs-substance-property-pq-example-ph-aq\"> </a></td><td>pH in aqueous solution</td></tr><tr><td style=\"white-space:nowrap\">hygroscopy<a name=\"cs-substance-property-pq-example-hygroscopy\"> </a></td><td>Hygroscopy</td></tr><tr><td style=\"white-space:nowrap\">hygroscopy-hygroscopic<a name=\"cs-substance-property-pq-example-hygroscopy-hygroscopic\"> </a></td><td>Hygroscopic</td></tr><tr><td style=\"white-space:nowrap\">impurityClassificationMCP<a name=\"cs-substance-property-pq-example-impurityClassificationMCP\"> </a></td><td>Impurity Classification - Mutagenic and Carcinogenic Potential</td></tr><tr><td style=\"white-space:nowrap\">1233444<a name=\"cs-substance-property-pq-example-1233444\"> </a></td><td>Rule-based (Q)Sar</td></tr><tr><td style=\"white-space:nowrap\">123555<a name=\"cs-substance-property-pq-example-123555\"> </a></td><td>Statistical (Q)Sar</td></tr><tr><td style=\"white-space:nowrap\">123556<a name=\"cs-substance-property-pq-example-123556\"> </a></td><td>ICH M7 Classification</td></tr><tr><td style=\"white-space:nowrap\">123557<a name=\"cs-substance-property-pq-example-123557\"> </a></td><td>Mutagenicity Comment</td></tr></table></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg"^^xsd:anyURI ] ;
fhir:value [ fhir:v "brr" ]
  ] ) ; # 
  fhir:url [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI] ; # 
  fhir:identifier ( [
fhir:system [ fhir:v "urn:ietf:rfc:3986"^^xsd:anyURI ] ;
fhir:value [ fhir:v "urn:oid:2.16.840.1.113883.4.642.40.41.16.10" ]
  ] ) ; # 
  fhir:version [ fhir:v "1.0.0"] ; # 
  fhir:name [ fhir:v "CsSubstancePropertyPQ"] ; # 
  fhir:title [ fhir:v "Substance Property - example"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:experimental [ fhir:v "false"^^xsd:boolean] ; # 
  fhir:date [ fhir:v "2024-05-08T13:55:35+00:00"^^xsd:dateTime] ; # 
  fhir:publisher [ fhir:v "HL7 International / Biomedical Research and Regulation"] ; # 
  fhir:contact ( [
fhir:name [ fhir:v "HL7 International - Biomedical Research and Regulation" ] ;
    ( fhir:telecom [
fhir:system [ fhir:v "url" ] ;
fhir:value [ fhir:v "http://www.hl7.org/Special/committees/rcrim" ]     ] )
  ] ) ; # 
  fhir:description [ fhir:v "This example code system contains example codes for substance property types used in pharmaceutical quality industry."] ; # 
  fhir:jurisdiction ( [
    ( fhir:coding [
fhir:system [ fhir:v "http://unstats.un.org/unsd/methods/m49/m49.htm"^^xsd:anyURI ] ;
fhir:code [ fhir:v "001" ] ;
fhir:display [ fhir:v "World" ]     ] ) ;
fhir:text [ fhir:v "World" ]
  ] ) ; # 
  fhir:caseSensitive [ fhir:v "true"^^xsd:boolean] ; # 
  fhir:content [ fhir:v "complete"] ; # 
  fhir:concept ( [
fhir:code [ fhir:v "solubility-water" ] ;
fhir:display [ fhir:v "Solubility purified water" ]
  ] [
fhir:code [ fhir:v "water-content" ] ;
fhir:display [ fhir:v "Water content" ]
  ] [
fhir:code [ fhir:v "appearance" ] ;
fhir:display [ fhir:v "Appearance" ]
  ] [
fhir:code [ fhir:v "solubility-water-pheur" ] ;
fhir:display [ fhir:v "Solubility purified water (PhEur)" ]
  ] [
fhir:code [ fhir:v "solubility-acetone-pheur" ] ;
fhir:display [ fhir:v "Solubility Acetone (PhEur)" ]
  ] [
fhir:code [ fhir:v "solubility-ethanol-pheur" ] ;
fhir:display [ fhir:v "Solubility Ethanol (PhEur)" ]
  ] [
fhir:code [ fhir:v "solubility-aq-water-2h-approx" ] ;
fhir:display [ fhir:v "Solubility at saturation in Purifed Water after 2 hours (approx)" ]
  ] [
fhir:code [ fhir:v "solubility-aq-glucose-2h-approx" ] ;
fhir:display [ fhir:v "Solubility at saturation in Glucose (5%) after 2 hours (approx)" ]
  ] [
fhir:code [ fhir:v "pH" ] ;
fhir:display [ fhir:v "pH" ]
  ] [
fhir:code [ fhir:v "solubility-usp-ph" ] ;
fhir:display [ fhir:v "Solubility as a function of pH in USP buffers" ]
  ] [
fhir:code [ fhir:v "concentration" ] ;
fhir:display [ fhir:v "Concentration" ]
  ] [
fhir:code [ fhir:v "temperature" ] ;
fhir:display [ fhir:v "Temperature" ]
  ] [
fhir:code [ fhir:v "ph-aq" ] ;
fhir:display [ fhir:v "pH in aqueous solution" ]
  ] [
fhir:code [ fhir:v "hygroscopy" ] ;
fhir:display [ fhir:v "Hygroscopy" ]
  ] [
fhir:code [ fhir:v "hygroscopy-hygroscopic" ] ;
fhir:display [ fhir:v "Hygroscopic" ]
  ] [
fhir:code [ fhir:v "impurityClassificationMCP" ] ;
fhir:display [ fhir:v "Impurity Classification - Mutagenic and Carcinogenic Potential" ]
  ] [
fhir:code [ fhir:v "1233444" ] ;
fhir:display [ fhir:v "Rule-based (Q)Sar" ]
  ] [
fhir:code [ fhir:v "123555" ] ;
fhir:display [ fhir:v "Statistical (Q)Sar" ]
  ] [
fhir:code [ fhir:v "123556" ] ;
fhir:display [ fhir:v "ICH M7 Classification" ]
  ] [
fhir:code [ fhir:v "123557" ] ;
fhir:display [ fhir:v "Mutagenicity Comment" ]
  ] ) . #