Pharmaceutical Quality (Industry)
1.0.0 - STU1
Pharmaceutical Quality (Industry)
1.0.0 - STU1
This page is part of the Pharmaceutical Quality (Industry) (v1.0.0: STU1) based on FHIR (HL7® FHIR® Standard) v5.0.0. This is the current published version. For a full list of available versions, see the Directory of published versions
@prefix fhir: <http://hl7.org/fhir/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- a fhir:Bundle ; fhir:nodeRole fhir:treeRoot ; fhir:id [ fhir:v "bundle-product-impurities-pq-ex2-sub"] ; # Substance Impurities fhir:meta [ ( fhir:profile [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-product-impurities-pq"^^xsd:anyURI ; fhir:link <http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Bundle-product-impurities-pq> ] ) ] ; # fhir:type [ fhir:v "collection"] ; # fhir:entry ( [ fhir:fullUrl [ fhir:v "urn:uuid:03d68d1c-162c-8b6e-70f9-647b0ea97adb"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:03d68d1c-162c-8b6e-70f9-647b0ea97adb> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad1"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad1> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad1"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad1> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad2"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad2> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad2"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad2> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad9"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad9> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad9"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad9> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad3"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad3> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad3"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad3> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad4"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad4> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad4"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad4> ) ] [ fhir:fullUrl [ fhir:v "urn:uuid:062bf235-44e2-55c4-9213-bbe5e12d5620"^^xsd:anyURI ] ; ( fhir:resource <urn:uuid:062bf235-44e2-55c4-9213-bbe5e12d5620> ) ] ) . # <urn:uuid:03d68d1c-162c-8b6e-70f9-647b0ea97adb> a fhir:SubstanceDefinition ; fhir:id [ fhir:v "substance1"] ; # fhir:text [ fhir:status [ fhir:v "extensions" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_substance1\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"substance1\"> </a><a name=\"hcsubstance1\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "substance1" </p></div><p><b>manufacturer</b>: See on this page: Organization/062bf235-44e2-55c4-9213-bbe5e12d5620</p><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Stelbatolol</td></tr></table><blockquote><p><b>relationship</b></p><p><b>Extension - Impurity Origin PQ</b>: Enantiomer of API SM <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-impurity-origin.html\">Impurity Origin Codes</a>#enantiomer "Enantiomer")</span></p><p><b>substanceDefinition</b>: See on this page: SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad1</p><p><b>type</b>: Impurity Of <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-substance-relationship-type.html\">Substance Relationship Type</a>#Impurity; <a href=\"CodeSystem-impurity-type.html\">Impurity Type Codes</a>#CH-IMP "Chiral Impurity")</span></p><p><b>amount</b>: ND</p></blockquote><blockquote><p><b>relationship</b></p><p><b>Extension - Impurity Origin PQ</b>: Step 1a Process Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-impurity-origin.html\">Impurity Origin Codes</a>#process "Process Impurity")</span></p><p><b>substanceDefinition</b>: See on this page: SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad2</p><p><b>type</b>: Impurity Of <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-substance-relationship-type.html\">Substance Relationship Type</a>#Impurity; <a href=\"CodeSystem-impurity-type.html\">Impurity Type Codes</a>#PR-IMP "Process impurity")</span></p><p><b>amount</b>: Range: ND-0.2%</p></blockquote><blockquote><p><b>relationship</b></p><p><b>Extension - Impurity Origin PQ</b>: Step 1a Process Impurity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-impurity-origin.html\">Impurity Origin Codes</a>#process "Process Impurity")</span></p><p><b>substanceDefinition</b>: See on this page: SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad9</p><p><b>type</b>: Impurity Of <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-substance-relationship-type.html\">Substance Relationship Type</a>#Impurity; <a href=\"CodeSystem-impurity-type.html\">Impurity Type Codes</a>#PR-IMP "Process impurity")</span></p><p><b>amount</b>: Range: ND–0.3%</p></blockquote><blockquote><p><b>relationship</b></p><p><b>Extension - Impurity Origin PQ</b>: API Starting Material <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-impurity-origin.html\">Impurity Origin Codes</a>#starting-material "Starting Material")</span></p><p><b>substanceDefinition</b>: See on this page: SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad3</p><p><b>type</b>: Impurity Of <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-substance-relationship-type.html\">Substance Relationship Type</a>#Impurity; <a href=\"CodeSystem-impurity-type.html\">Impurity Type Codes</a>#ST-IMP "Starting material, forced degradation product")</span></p><p><b>amount</b>: Observed only during stress studies</p></blockquote><blockquote><p><b>relationship</b></p><p><b>Extension - Impurity Origin PQ</b>: API Process Intermediate <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-impurity-origin.html\">Impurity Origin Codes</a>#intermediate-material "Intermediate Material")</span></p><p><b>substanceDefinition</b>: See on this page: SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad4</p><p><b>type</b>: Impurity Of <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-substance-relationship-type.html\">Substance Relationship Type</a>#Impurity; <a href=\"CodeSystem-impurity-type.html\">Impurity Type Codes</a>#INT-IMP "Process intermediate, forced degradation product")</span></p><p><b>amount</b>: Observed only during stress studies</p></blockquote></div>" ] ; # fhir:manufacturer ( [ fhir:reference [ fhir:v "Organization/062bf235-44e2-55c4-9213-bbe5e12d5620" ] # Organization\/substance-manufacturer ] ) ; # fhir:name ( [ fhir:name [ fhir:v "Stelbatolol" ] ] ) ; # fhir:relationship ( [ ( fhir:extension [ fhir:url [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-impurity-origin-pq"^^xsd:anyURI ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-origin"^^xsd:anyURI ] ; fhir:code [ fhir:v "enantiomer" ] ; fhir:display [ fhir:v "Enantiomer" ] ] ) ; fhir:text [ fhir:v "Enantiomer of API SM" ] ] ] ) ; fhir:substanceDefinition [ a fhir:Reference ; fhir:reference [ fhir:v "SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad1" ] # SubstanceDefinition\/impurityEnantiomer ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/substance-relationship-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "Impurity" ] ; fhir:display [ fhir:v "Impurity Of" ] ] [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "CH-IMP" ] ; fhir:display [ fhir:v "Chiral Impurity" ] ] ) # two codes here, one is more specialised than the other ] ; fhir:amount [ fhir:v "ND" ] ] [ ( fhir:extension [ fhir:url [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-impurity-origin-pq"^^xsd:anyURI ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-origin"^^xsd:anyURI ] ; fhir:code [ fhir:v "process" ] ; fhir:display [ fhir:v "Process Impurity" ] ] ) ; fhir:text [ fhir:v "Step 1a Process Impurity" ] ] ] ) ; fhir:substanceDefinition [ a fhir:Reference ; fhir:reference [ fhir:v "SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad2" ] # SubstanceDefinition\/impurity1 ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/substance-relationship-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "Impurity" ] ; fhir:display [ fhir:v "Impurity Of" ] ] [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "PR-IMP" ] ; fhir:display [ fhir:v "Process impurity" ] ] ) ] ; fhir:amount [ fhir:v "Range: ND-0.2%" ] ] [ ( fhir:extension [ fhir:url [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-impurity-origin-pq"^^xsd:anyURI ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-origin"^^xsd:anyURI ] ; fhir:code [ fhir:v "process" ] ; fhir:display [ fhir:v "Process Impurity" ] ] ) ; fhir:text [ fhir:v "Step 1a Process Impurity" ] ] ] ) ; fhir:substanceDefinition [ a fhir:Reference ; fhir:reference [ fhir:v "SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad9" ] # SubstanceDefinition\/impurity2 ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/substance-relationship-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "Impurity" ] ; fhir:display [ fhir:v "Impurity Of" ] ] [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "PR-IMP" ] ; fhir:display [ fhir:v "Process impurity" ] ] ) ] ; fhir:amount [ fhir:v "Range: ND–0.3%" ] ] [ ( fhir:extension [ fhir:url [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-impurity-origin-pq"^^xsd:anyURI ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-origin"^^xsd:anyURI ] ; fhir:code [ fhir:v "starting-material" ] ; fhir:display [ fhir:v "Starting Material" ] ] ) ; fhir:text [ fhir:v "API Starting Material" ] ] ] ) ; fhir:substanceDefinition [ a fhir:Reference ; fhir:reference [ fhir:v "SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad3" ] # SubstanceDefinition\/impurityNapthol ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/substance-relationship-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "Impurity" ] ; fhir:display [ fhir:v "Impurity Of" ] ] [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "ST-IMP" ] ; fhir:display [ fhir:v "Starting material, forced degradation product" ] ] ) ] ; fhir:amount [ fhir:v "Observed only during stress studies" ] ] [ ( fhir:extension [ fhir:url [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/StructureDefinition/Extension-impurity-origin-pq"^^xsd:anyURI ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-origin"^^xsd:anyURI ] ; fhir:code [ fhir:v "intermediate-material" ] ; fhir:display [ fhir:v "Intermediate Material" ] ] ) ; fhir:text [ fhir:v "API Process Intermediate" ] ] ] ) ; fhir:substanceDefinition [ a fhir:Reference ; fhir:reference [ fhir:v "SubstanceDefinition/03d68d1c-162c-8b6e-80f9-647b0ea97ad4" ] # SubstanceDefinition\/impurityPropanol ] ; fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/substance-relationship-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "Impurity" ] ; fhir:display [ fhir:v "Impurity Of" ] ] [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/impurity-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "INT-IMP" ] ; fhir:display [ fhir:v "Process intermediate, forced degradation product" ] ] ) ] ; fhir:amount [ fhir:v "Observed only during stress studies" ] ] ) . # <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad1> a fhir:SubstanceDefinition ; fhir:id [ fhir:v "03d68d1c-162c-8b6e-80f9-647b0ea97ad1"] ; # impurityEnantiomer fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_03d68d1c-162c-8b6e-80f9-647b0ea97ad1\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"03d68d1c-162c-8b6e-80f9-647b0ea97ad1\"> </a><a name=\"hc03d68d1c-162c-8b6e-80f9-647b0ea97ad1\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "03d68d1c-162c-8b6e-80f9-647b0ea97ad1" </p></div><blockquote><p><b>characterization</b></p><p><b>technique</b>: Enantiomeric purity by LC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>characterization</b></p><p><b>technique</b>: Mass spectrometry <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Rule-based (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#1233444)</span></p><p><b>value</b>: Negative <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#negative)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Statistical (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123555)</span></p><p><b>value</b>: Negative <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#negative)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: ICH M7 Classification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123556)</span></p><p><b>value</b>: Class 5 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#class-5)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Mutagenicity Comment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123557)</span></p><p><b>value</b>: Treated as non-mutagenic due to lack of alerting structure <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><h3>MolecularWeights</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Amount</b></td></tr><tr><td style=\"display: none\">*</td><td>295.80 g/mole<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code g/mol = 'g/mol')</span></td></tr></table><blockquote><p><b>structure</b></p><h3>Representations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Document</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: DocumentReference/13d68d1c-162c-8b6e-80f9-647b0ea97ad1</td></tr></table></blockquote><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>R-enantiomer of stelbatalol</td></tr></table></div>" ] ; # fhir:characterization ( [ fhir:technique [ fhir:text [ fhir:v "Enantiomeric purity by LC" ] ] ] [ fhir:technique [ fhir:text [ fhir:v "Mass spectrometry" ] ] ] ) ; # fhir:property ( [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "1233444" ] ; fhir:display [ fhir:v "Rule-based (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "negative" ] ; fhir:display [ fhir:v "Negative" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123555" ] ; fhir:display [ fhir:v "Statistical (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "negative" ] ; fhir:display [ fhir:v "Negative" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123556" ] ; fhir:display [ fhir:v "ICH M7 Classification" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "class-5" ] ; fhir:display [ fhir:v "Class 5" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123557" ] ; fhir:display [ fhir:v "Mutagenicity Comment" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; fhir:text [ fhir:v "Treated as non-mutagenic due to lack of alerting structure" ] ] ] ) ; # fhir:molecularWeight ( [ fhir:amount [ fhir:value [ fhir:v "295.80"^^xsd:decimal ] ; fhir:unit [ fhir:v "g/mole" ] ; fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ; fhir:code [ fhir:v "g/mol" ] ] ] ) ; # fhir:structure [ ( fhir:representation [ fhir:document [ fhir:reference [ fhir:v "DocumentReference/13d68d1c-162c-8b6e-80f9-647b0ea97ad1" ] # DocumentReference\/impurityEnantiomerdoc ] ] ) ] ; # fhir:name ( [ fhir:name [ fhir:v "R-enantiomer of stelbatalol" ] ] ) . # <urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad1> a fhir:DocumentReference ; fhir:id [ fhir:v "13d68d1c-162c-8b6e-80f9-647b0ea97ad1"] ; # impurityEnantiomerdoc fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DocumentReference_13d68d1c-162c-8b6e-80f9-647b0ea97ad1\"> </a><p><b>Generated Narrative: DocumentReference</b><a name=\"13d68d1c-162c-8b6e-80f9-647b0ea97ad1\"> </a><a name=\"hc13d68d1c-162c-8b6e-80f9-647b0ea97ad1\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DocumentReference "13d68d1c-162c-8b6e-80f9-647b0ea97ad1" </p></div><p><b>status</b>: current</p><blockquote><p><b>content</b></p><h3>Attachments</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ContentType</b></td><td><b>Data</b></td></tr><tr><td style=\"display: none\">*</td><td>image/x-png</td><td>(base64 data - 4429 bytes)</td></tr></table></blockquote></div>" ] ; # fhir:status [ fhir:v "current"] ; # fhir:content ( [ fhir:attachment [ fhir:contentType [ fhir:v "image/x-png" ] ; fhir:data [ fhir:v "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"^^xsd:base64Binary ] ] ] ) . # <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad2> a fhir:SubstanceDefinition ; fhir:id [ fhir:v "03d68d1c-162c-8b6e-80f9-647b0ea97ad2"] ; # impurity1 fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_03d68d1c-162c-8b6e-80f9-647b0ea97ad2\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"03d68d1c-162c-8b6e-80f9-647b0ea97ad2\"> </a><a name=\"hc03d68d1c-162c-8b6e-80f9-647b0ea97ad2\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "03d68d1c-162c-8b6e-80f9-647b0ea97ad2" </p></div><h3>Characterizations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Technique</b></td></tr><tr><td style=\"display: none\">*</td><td>Organic impurities by HPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><blockquote><p><b>property</b></p><p><b>type</b>: Rule-based (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#1233444)</span></p><p><b>value</b>: Negative <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#negative)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Statistical (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123555)</span></p><p><b>value</b>: Negative <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#negative)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: ICH M7 Classification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123556)</span></p><p><b>value</b>: Class 5 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#class-5)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Mutagenicity Comment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123557)</span></p><p><b>value</b>: Treated as non-mutagenic due to lack of alerting structure <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><h3>MolecularWeights</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Amount</b></td></tr><tr><td style=\"display: none\">*</td><td>344.4 g/mole<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code g/mol = 'g/mol')</span></td></tr></table><blockquote><p><b>structure</b></p><h3>Representations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Document</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: DocumentReference/13d68d1c-162c-8b6e-80f9-647b0ea97ad2</td></tr></table></blockquote><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity 1</td></tr></table></div>" ] ; # fhir:characterization ( [ fhir:technique [ fhir:text [ fhir:v "Organic impurities by HPLC" ] ] ] ) ; # fhir:property ( [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "1233444" ] ; fhir:display [ fhir:v "Rule-based (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "negative" ] ; fhir:display [ fhir:v "Negative" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123555" ] ; fhir:display [ fhir:v "Statistical (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "negative" ] ; fhir:display [ fhir:v "Negative" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123556" ] ; fhir:display [ fhir:v "ICH M7 Classification" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "class-5" ] ; fhir:display [ fhir:v "Class 5" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123557" ] ; fhir:display [ fhir:v "Mutagenicity Comment" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; fhir:text [ fhir:v "Treated as non-mutagenic due to lack of alerting structure" ] ] ] ) ; # fhir:molecularWeight ( [ fhir:amount [ fhir:value [ fhir:v "344.4"^^xsd:decimal ] ; fhir:unit [ fhir:v "g/mole" ] ; fhir:system [ fhir:v 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0px\">Resource DocumentReference "13d68d1c-162c-8b6e-80f9-647b0ea97ad2" </p></div><p><b>status</b>: current</p><blockquote><p><b>content</b></p><h3>Attachments</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ContentType</b></td><td><b>Data</b></td></tr><tr><td style=\"display: none\">*</td><td>image/x-png</td><td>(base64 data - 7004 bytes)</td></tr></table></blockquote></div>" ] ; # fhir:status [ fhir:v "current"] ; # fhir:content ( [ fhir:attachment [ fhir:contentType [ fhir:v "image/x-png" ] ; fhir:data [ fhir:v 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"^^xsd:base64Binary ] ] ] ) . # <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad9> a fhir:SubstanceDefinition ; fhir:id [ fhir:v "03d68d1c-162c-8b6e-80f9-647b0ea97ad9"] ; # impurity2 fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_03d68d1c-162c-8b6e-80f9-647b0ea97ad9\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"03d68d1c-162c-8b6e-80f9-647b0ea97ad9\"> </a><a name=\"hc03d68d1c-162c-8b6e-80f9-647b0ea97ad9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "03d68d1c-162c-8b6e-80f9-647b0ea97ad9" </p></div><h3>Characterizations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Technique</b></td></tr><tr><td style=\"display: none\">*</td><td>Organic impurities by LC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table><blockquote><p><b>property</b></p><p><b>type</b>: Rule-based (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#1233444)</span></p><p><b>value</b>: Negative <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#negative)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Statistical (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123555)</span></p><p><b>value</b>: Negative <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#negative)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: ICH M7 Classification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123556)</span></p><p><b>value</b>: Class 5 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#class-5)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Mutagenicity Comment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123557)</span></p><p><b>value</b>: Treated as non-mutagenic due to lack of alerting structure <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><h3>MolecularWeights</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Amount</b></td></tr><tr><td style=\"display: none\">*</td><td>459.58 g/mole<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code g/mol = 'g/mol')</span></td></tr></table><blockquote><p><b>structure</b></p><h3>Representations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Document</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: DocumentReference/13d68d1c-162c-8b6e-80f9-647b0ea97ad9</td></tr></table></blockquote><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>Impurity 2</td></tr></table></div>" ] ; # fhir:characterization ( [ fhir:technique [ fhir:text [ fhir:v "Organic impurities by LC" ] ] ] ) ; # fhir:property ( [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "1233444" ] ; fhir:display [ fhir:v "Rule-based (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "negative" ] ; fhir:display [ fhir:v "Negative" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123555" ] ; fhir:display [ fhir:v "Statistical (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "negative" ] ; fhir:display [ fhir:v "Negative" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123556" ] ; fhir:display [ fhir:v "ICH M7 Classification" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "class-5" ] ; fhir:display [ fhir:v "Class 5" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123557" ] ; fhir:display [ fhir:v "Mutagenicity Comment" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; fhir:text [ fhir:v "Treated as non-mutagenic due to lack of alerting structure" ] ] ] ) ; # fhir:molecularWeight ( [ fhir:amount [ fhir:value [ fhir:v "459.58"^^xsd:decimal ] ; fhir:unit [ fhir:v "g/mole" ] ; fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ; fhir:code [ fhir:v "g/mol" ] ] ] ) ; # fhir:structure [ ( fhir:representation [ fhir:document [ fhir:reference [ fhir:v "DocumentReference/13d68d1c-162c-8b6e-80f9-647b0ea97ad9" ] # DocumentReference\/impurity2doc ] ] ) ] ; # fhir:name ( [ fhir:name [ fhir:v "Impurity 2" ] ] ) . # <urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad9> a fhir:DocumentReference ; fhir:id [ fhir:v "13d68d1c-162c-8b6e-80f9-647b0ea97ad9"] ; # impurity2doc fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DocumentReference_13d68d1c-162c-8b6e-80f9-647b0ea97ad9\"> </a><p><b>Generated Narrative: DocumentReference</b><a name=\"13d68d1c-162c-8b6e-80f9-647b0ea97ad9\"> </a><a name=\"hc13d68d1c-162c-8b6e-80f9-647b0ea97ad9\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DocumentReference "13d68d1c-162c-8b6e-80f9-647b0ea97ad9" </p></div><p><b>status</b>: current</p><blockquote><p><b>content</b></p><h3>Attachments</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ContentType</b></td><td><b>Data</b></td></tr><tr><td style=\"display: none\">*</td><td>image/x-png</td><td>(base64 data - 7149 bytes)</td></tr></table></blockquote></div>" ] ; # fhir:status [ fhir:v "current"] ; # fhir:content ( [ fhir:attachment [ fhir:contentType [ fhir:v "image/x-png" ] ; fhir:data [ fhir:v "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"^^xsd:base64Binary ] ] ] ) . # <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad3> a fhir:SubstanceDefinition ; fhir:id [ fhir:v "03d68d1c-162c-8b6e-80f9-647b0ea97ad3"] ; # impurityNapthol fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_03d68d1c-162c-8b6e-80f9-647b0ea97ad3\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"03d68d1c-162c-8b6e-80f9-647b0ea97ad3\"> </a><a name=\"hc03d68d1c-162c-8b6e-80f9-647b0ea97ad3\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "03d68d1c-162c-8b6e-80f9-647b0ea97ad3" </p></div><blockquote><p><b>characterization</b></p><p><b>technique</b>: Organic impurities by HPLC <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>characterization</b></p><p><b>technique</b>: Chromatographic retention <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Rule-based (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#1233444)</span></p><p><b>value</b>: Negative <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#negative)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Statistical (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123555)</span></p><p><b>value</b>: Negative <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#negative)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: ICH M7 Classification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123556)</span></p><p><b>value</b>: Class 5 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#class-5)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Mutagenicity Comment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123557)</span></p><p><b>value</b>: Treated as non-mutagenic due to lack of alerting structure <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><h3>MolecularWeights</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Amount</b></td></tr><tr><td style=\"display: none\">*</td><td>144.173 g/mole<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code g/mol = 'g/mol')</span></td></tr></table><blockquote><p><b>structure</b></p><blockquote><p><b>representation</b></p><p><b>document</b>: See on this page: DocumentReference/13d68d1c-162c-8b6e-80f9-647b0ea97ad3</p></blockquote><blockquote><p><b>representation</b></p><p><b>type</b>: SMILES <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-substance-representation-format.html\">Substance Representation Format</a>#SMILES)</span></p><p><b>representation</b>: OC1=CC2=C(C=C1)C=CC=C2</p></blockquote><blockquote><p><b>representation</b></p><p><b>type</b>: InChI <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-substance-representation-format.html\">Substance Representation Format</a>#InChI)</span></p><p><b>representation</b>: 1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H</p></blockquote></blockquote><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>2-Naphthol <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-CAS.html\">Chemical abstract codes</a>#135-19-3)</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>β-naphthol</td></tr></table></div>" ] ; # fhir:characterization ( [ fhir:technique [ fhir:text [ fhir:v "Organic impurities by HPLC" ] ] ] [ fhir:technique [ fhir:text [ fhir:v "Chromatographic retention" ] ] ] ) ; # fhir:property ( [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "1233444" ] ; fhir:display [ fhir:v "Rule-based (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "negative" ] ; fhir:display [ fhir:v "Negative" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123555" ] ; fhir:display [ fhir:v "Statistical (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "negative" ] ; fhir:display [ fhir:v "Negative" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123556" ] ; fhir:display [ fhir:v "ICH M7 Classification" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "class-5" ] ; fhir:display [ fhir:v "Class 5" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123557" ] ; fhir:display [ fhir:v "Mutagenicity Comment" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; fhir:text [ fhir:v "Treated as non-mutagenic due to lack of alerting structure" ] ] ] ) ; # fhir:molecularWeight ( [ fhir:amount [ fhir:value [ fhir:v "144.173"^^xsd:decimal ] ; fhir:unit [ fhir:v "g/mole" ] ; fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ; fhir:code [ fhir:v "g/mol" ] ] ] ) ; # fhir:structure [ ( fhir:representation [ fhir:document [ fhir:reference [ fhir:v "DocumentReference/13d68d1c-162c-8b6e-80f9-647b0ea97ad3" ] # DocumentReference\/impurityNaptholDoc ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/substance-representation-format"^^xsd:anyURI ] ; fhir:code [ fhir:v "SMILES" ] ; fhir:display [ fhir:v "SMILES" ] ] ) ] ; fhir:representation [ fhir:v "OC1=CC2=C(C=C1)C=CC=C2" ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/substance-representation-format"^^xsd:anyURI ] ; fhir:code [ fhir:v "InChI" ] ; fhir:display [ fhir:v "InChI" ] ] ) ] ; fhir:representation [ fhir:v "1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H" ] ] ) ] ; # fhir:code ( [ fhir:code [ ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/CAS"^^xsd:anyURI ] ; fhir:code [ fhir:v "135-19-3" ] ; fhir:display [ fhir:v "2-Naphthol" ] ] ) ] ] ) ; # fhir:name ( [ fhir:name [ fhir:v "β-naphthol" ] ] ) . # <urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad3> a fhir:DocumentReference ; fhir:id [ fhir:v "13d68d1c-162c-8b6e-80f9-647b0ea97ad3"] ; # impurityNaptholDoc fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DocumentReference_13d68d1c-162c-8b6e-80f9-647b0ea97ad3\"> </a><p><b>Generated Narrative: DocumentReference</b><a name=\"13d68d1c-162c-8b6e-80f9-647b0ea97ad3\"> </a><a name=\"hc13d68d1c-162c-8b6e-80f9-647b0ea97ad3\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DocumentReference "13d68d1c-162c-8b6e-80f9-647b0ea97ad3" </p></div><p><b>status</b>: current</p><blockquote><p><b>content</b></p><h3>Attachments</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ContentType</b></td><td><b>Data</b></td></tr><tr><td style=\"display: none\">*</td><td>image/x-png</td><td>(base64 data - 4093 bytes)</td></tr></table></blockquote></div>" ] ; # fhir:status [ fhir:v "current"] ; # fhir:content ( [ fhir:attachment [ fhir:contentType [ fhir:v "image/x-png" ] ; fhir:data [ fhir:v "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"^^xsd:base64Binary ] ] ] ) . # <urn:uuid:03d68d1c-162c-8b6e-80f9-647b0ea97ad4> a fhir:SubstanceDefinition ; fhir:id [ fhir:v "03d68d1c-162c-8b6e-80f9-647b0ea97ad4"] ; # impurityPropanol fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_03d68d1c-162c-8b6e-80f9-647b0ea97ad4\"> </a><p><b>Generated Narrative: SubstanceDefinition</b><a name=\"03d68d1c-162c-8b6e-80f9-647b0ea97ad4\"> </a><a name=\"hc03d68d1c-162c-8b6e-80f9-647b0ea97ad4\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstanceDefinition "03d68d1c-162c-8b6e-80f9-647b0ea97ad4" </p></div><blockquote><p><b>characterization</b></p><p><b>technique</b>: Impurity content by LC-MS <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>characterization</b></p><p><b>technique</b>: UV spectroscopy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>characterization</b></p><p><b>technique</b>: NMR spectroscopy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Rule-based (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#1233444)</span></p><p><b>value</b>: Positive <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#positive)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Statistical (Q)Sar <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123555)</span></p><p><b>value</b>: Positive <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#positive)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: ICH M7 Classification <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123556)</span></p><p><b>value</b>: Class 2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-value-pq-example.html\">Substance Property Value - example</a>#class-2)</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: Mutagenicity Comment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-substance-property-pq-example.html\">Substance Property - example</a>#123557)</span></p><p><b>value</b>: Control at or below qualification threshold <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><h3>MolecularWeights</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Amount</b></td></tr><tr><td style=\"display: none\">*</td><td>245.32 g/mole<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code g/mol = 'g/mol')</span></td></tr></table><blockquote><p><b>structure</b></p><h3>Representations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Document</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: DocumentReference/13d68d1c-162c-8b6e-80f9-647b0ea97ad4</td></tr></table></blockquote><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td></tr><tr><td style=\"display: none\">*</td><td>1-(Ethylamino)-3-(2-naphthyloxy)-2-propanol</td></tr></table></div>" ] ; # fhir:characterization ( [ fhir:technique [ fhir:text [ fhir:v "Impurity content by LC-MS" ] ] ] [ fhir:technique [ fhir:text [ fhir:v "UV spectroscopy" ] ] ] [ fhir:technique [ fhir:text [ fhir:v "NMR spectroscopy" ] ] ] ) ; # fhir:property ( [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "1233444" ] ; fhir:display [ fhir:v "Rule-based (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "positive" ] ; fhir:display [ fhir:v "Positive" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123555" ] ; fhir:display [ fhir:v "Statistical (Q)Sar" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "positive" ] ; fhir:display [ fhir:v "Positive" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123556" ] ; fhir:display [ fhir:v "ICH M7 Classification" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-value-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "class-2" ] ; fhir:display [ fhir:v "Class 2" ] ] ) ] ] [ fhir:type [ ( fhir:coding [ fhir:system [ fhir:v "http://hl7.org/fhir/uv/pharm-quality/CodeSystem/cs-substance-property-pq-example"^^xsd:anyURI ] ; fhir:code [ fhir:v "123557" ] ; fhir:display [ fhir:v "Mutagenicity Comment" ] ] ) ] ; fhir:value [ a fhir:CodeableConcept ; fhir:text [ fhir:v "Control at or below qualification threshold" ] ] ] ) ; # fhir:molecularWeight ( [ fhir:amount [ fhir:value [ fhir:v "245.32"^^xsd:decimal ] ; fhir:unit [ fhir:v "g/mole" ] ; fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ; fhir:code [ fhir:v "g/mol" ] ] ] ) ; # fhir:structure [ ( fhir:representation [ fhir:document [ fhir:reference [ fhir:v "DocumentReference/13d68d1c-162c-8b6e-80f9-647b0ea97ad4" ] # DocumentReference\/impurityPropanolDoc ] ] ) ] ; # fhir:name ( [ fhir:name [ fhir:v "1-(Ethylamino)-3-(2-naphthyloxy)-2-propanol" ] ] ) . # not in CAS <urn:uuid:13d68d1c-162c-8b6e-80f9-647b0ea97ad4> a fhir:DocumentReference ; fhir:id [ fhir:v "13d68d1c-162c-8b6e-80f9-647b0ea97ad4"] ; # impurityPropanolDoc fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"DocumentReference_13d68d1c-162c-8b6e-80f9-647b0ea97ad4\"> </a><p><b>Generated Narrative: DocumentReference</b><a name=\"13d68d1c-162c-8b6e-80f9-647b0ea97ad4\"> </a><a name=\"hc13d68d1c-162c-8b6e-80f9-647b0ea97ad4\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource DocumentReference "13d68d1c-162c-8b6e-80f9-647b0ea97ad4" </p></div><p><b>status</b>: current</p><blockquote><p><b>content</b></p><h3>Attachments</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>ContentType</b></td><td><b>Data</b></td></tr><tr><td style=\"display: none\">*</td><td>image/x-png</td><td>(base64 data - 5119 bytes)</td></tr></table></blockquote></div>" ] ; # fhir:status [ fhir:v "current"] ; # fhir:content ( [ fhir:attachment [ fhir:contentType [ fhir:v "image/x-png" ] ; fhir:data [ fhir:v "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"^^xsd:base64Binary ] ] ] ) . # <urn:uuid:062bf235-44e2-55c4-9213-bbe5e12d5620> a fhir:Organization ; fhir:id [ fhir:v "062bf235-44e2-55c4-9213-bbe5e12d5620"] ; # substance-manufacturer fhir:text [ fhir:status [ fhir:v "generated" ] ; fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a><p><b>Generated Narrative: Organization</b><a name=\"062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a><a name=\"hc062bf235-44e2-55c4-9213-bbe5e12d5620\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Organization "062bf235-44e2-55c4-9213-bbe5e12d5620" </p></div><p><b>identifier</b>: <code>urn:oid:2.16.840.1.113883.4.82</code>/3003040516</p><p><b>active</b>: true</p><p><b>type</b>: Drug Substance Manufacture <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-pharmaceutical-organization-type.html\">Pharmaceutical Organization Type Codes</a>#drug-substance-manufacture)</span></p><p><b>name</b>: AAA Molybdenum Products, Inc.</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>7233 W 116th Pl Ste C Broomfield Colorado 80020 USA </td></tr></table></div>" ] ; # fhir:identifier ( [ fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.4.82"^^xsd:anyURI ] ; # FDA establishment identifier fhir:value [ fhir:v "3003040516" ] ] ) ; # fhir:active [ fhir:v "true"^^xsd:boolean] ; # fhir:type ( [ ( fhir:coding [ fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/pharmaceutical-organization-type"^^xsd:anyURI ] ; fhir:code [ fhir:v "drug-substance-manufacture" ] ; fhir:display [ fhir:v "Drug Substance Manufacture" ] ] ) ] ) ; # fhir:name [ fhir:v "AAA Molybdenum Products, Inc."] ; # fhir:contact ( [ fhir:address [ ( fhir:line [ fhir:v "7233 W 116th Pl" ] [ fhir:v "Ste C" ] ) ; fhir:city [ fhir:v "Broomfield" ] ; fhir:state [ fhir:v "Colorado" ] ; fhir:postalCode [ fhir:v "80020" ] ; fhir:country [ fhir:v "USA" ] ] ] ) . #
IG © HL7 International / Biomedical Research and Regulation. Package hl7.fhir.uv.pharm-quality#1.0.0 based on FHIR 5.0.0. Generated 2024-05-08
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