Genomics Reporting Implementation Guide
2.0.0 - trial-use

This page is part of the Genetic Reporting Implementation Guide (v2.0.0: STU 2) based on FHIR R4. This is the current published version in its permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions

: High Low codes - XML Representation

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<ValueSet xmlns="http://hl7.org/fhir">
  <id value="high-low-codes-vs"/>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><ul><li>Include these codes as defined in <a href="http://terminology.hl7.org/3.1.0/CodeSystem-v3-ObservationInterpretation.html"><code>http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation</code></a><table class="none"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td><a href="http://terminology.hl7.org/3.1.0/CodeSystem-v3-ObservationInterpretation.html#v3-ObservationInterpretation-H">H</a></td><td>High</td><td>The result for a quantitative observation is above the upper limit of the reference range (as defined for the respective test procedure).<br/><br/>Synonym: Above high normal</td></tr><tr><td><a href="http://terminology.hl7.org/3.1.0/CodeSystem-v3-ObservationInterpretation.html#v3-ObservationInterpretation-L">L</a></td><td>Low</td><td>The result for a quantitative observation is below the lower limit of the reference range (as defined for the respective test procedure).<br/><br/>Synonym: Below low normal</td></tr><tr><td><a href="http://terminology.hl7.org/3.1.0/CodeSystem-v3-ObservationInterpretation.html#v3-ObservationInterpretation-I">I</a></td><td>Intermediate</td><td>Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with uncertain therapeutic effect. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2<br/><br/>\[Note 1: Bacterial strains are categorized as intermediate by applying the appropriate breakpoints in a defined phenotypic test system.\]<br/><br/>\[Note 2: This class of susceptibility implies that an infection due to the isolate can be appropriately treated in body sites where the drugs are physiologically concentrated or when a high dosage of drug can be used.\]<br/><br/>\[Note 3: This class also indicates a &quot;buffer zone,&quot; to prevent small, uncontrolled, technical factors from causing major discrepancies in interpretations.\]<br/><br/>\[Note 4: These breakpoints can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\]</td></tr></table></li></ul></div>
  </text>
  <url
       value="http://hl7.org/fhir/uv/genomics-reporting/ValueSet/high-low-codes-vs"/>
  <version value="2.0.0"/>
  <name value="HighLowCodesVS"/>
  <title value="High Low codes"/>
  <status value="active"/>
  <date value="2022-05-09T16:53:07+00:00"/>
  <publisher value="HL7 Clinical Genomics Working Group"/>
  <contact>
    <name value="HL7 Clinical Genomics Working Group"/>
    <telecom>
      <system value="url"/>
      <value value="http://www.hl7.org/Special/committees/clingenomics"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="cg@lists.HL7.org"/>
    </telecom>
  </contact>
  <description
               value="This value set includes high/low codes for Observation Interpretations"/>
  <jurisdiction>
    <coding>
      <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
      <code value="001"/>
      <display value="World"/>
    </coding>
  </jurisdiction>
  <compose>
    <include>
      <system
              value="http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation"/>
      <concept>
        <code value="H"/>
        <display value="High"/>
      </concept>
      <concept>
        <code value="L"/>
        <display value="Low"/>
      </concept>
      <concept>
        <code value="I"/>
        <display value="Intermediate"/>
      </concept>
    </include>
  </compose>
</ValueSet>