Genomics Reporting Implementation Guide
2.0.0 - trial-use

This page is part of the Genetic Reporting Implementation Guide (v2.0.0: STU 2) based on FHIR R4. This is the current published version in its permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions

Example Task: PGxRecEx05

Generated Narrative

Resource "PGxRecEx05"

Profile: Followup Recommendation

status: requested

intent: proposal

code: Decrease dose (LOINC#LA26422-8)

description: For amitriptyline, a 50% reduction in starting dose is recommended with therapeutic drug monitoring to guide dose adjustment. Refer to current guidelines for dosage and recommendations at https://cpicpgx.org/guidelines/guideline-for- tricyclic-antidepressants-and-cyp2d6-and-cyp2c19/. If CYP2D6 genotyping is available, refer to the current guidelines for dosing recommendations.

for: Patient/CGPatientExample01 " EVERYMAN"

reasonReference: Observation/TxImp05: Poor metabolizer