This page is part of the Genetic Reporting Implementation Guide (v2.0.0: STU 2) based on FHIR R4. This is the current published version in its permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions
<Observation xmlns="http://hl7.org/fhir">
<id value="PolyGenicDiagnosticImpExample"/>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/diagnostic-implication"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource "PolyGenicDiagnosticImpExample" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-diagnostic-implication.html">Diagnostic Implication</a></p></div><p><b>Genomics Risk Assessment</b>: <a href="RiskAssessment-GenRiskDiabetesT2.html">RiskAssessment/GenRiskDiabetesT2: Polygenic Risk Score</a></p><p><b>status</b>: final</p><p><b>category</b>: Laboratory <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/3.1.0/CodeSystem-observation-category.html">Observation Category Codes</a>#laboratory)</span></p><p><b>code</b>: Diagnostic Implication <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-tbd-codes-cs.html">To Be Determined Codes</a>#diagnostic-implication)</span></p><p><b>subject</b>: <a href="Patient-CGPatientExample01.html">Patient/CGPatientExample01</a> " EVERYMAN"</p><p><b>performer</b>: <a href="Organization-ExampleOrg.html">Organization/ExampleOrg</a> "some lab"</p><p><b>derivedFrom</b>: </p><ul><li><span>: Variant 1</span></li><li><span>: Variant 2</span></li><li><span>: Variant 3</span></li><li><span>: Variant 4</span></li><li><span>: Variant 5</span></li><li><span>: Variant 6</span></li><li><span>: Variant 7</span></li></ul><blockquote><p><b>component</b></p><p><b>code</b>: Genetic variation clinical significance [Imp] <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#53037-8)</span></p><p><b>value</b>: Pathogenic <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#LA6668-3)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Associated phenotype <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#81259-4)</span></p><p><b>value</b>: Diabetes mellitus type 2 (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#44054006)</span></p></blockquote></div>
</text>
<extension
url="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomics-risk-assessment">
<valueReference>
<reference value="RiskAssessment/GenRiskDiabetesT2"/>
<display value="Polygenic Risk Score"/>
</valueReference>
</extension>
<status value="final"/>
<category>
<coding>
<system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs"/>
<code value="diagnostic-implication"/>
</coding>
</code>
<subject>
<reference value="Patient/CGPatientExample01"/>
</subject>
<performer>
<reference value="Organization/ExampleOrg"/>
</performer>
<derivedFrom>
<identifier>
<system value="http://hospital.example.org"/>
<value value="11"/>
</identifier>
<display value="Variant 1"/>
</derivedFrom>
<derivedFrom>
<identifier>
<system value="http://hospital.example.org"/>
<value value="12"/>
</identifier>
<display value="Variant 2"/>
</derivedFrom>
<derivedFrom>
<identifier>
<system value="http://hospital.example.org"/>
<value value="13"/>
</identifier>
<display value="Variant 3"/>
</derivedFrom>
<derivedFrom>
<identifier>
<system value="http://hospital.example.org"/>
<value value="14"/>
</identifier>
<display value="Variant 4"/>
</derivedFrom>
<derivedFrom>
<identifier>
<system value="http://hospital.example.org"/>
<value value="15"/>
</identifier>
<display value="Variant 5"/>
</derivedFrom>
<derivedFrom>
<identifier>
<system value="http://hospital.example.org"/>
<value value="16"/>
</identifier>
<display value="Variant 6"/>
</derivedFrom>
<derivedFrom>
<identifier>
<system value="http://hospital.example.org"/>
<value value="17"/>
</identifier>
<display value="Variant 7"/>
</derivedFrom>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="53037-8"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA6668-3"/>
<display value="Pathogenic"/>
</coding>
</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="81259-4"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="44054006"/>
<display value="Diabetes mellitus type 2 (disorder)"/>
</coding>
</valueCodeableConcept>
</component>
</Observation>