Genomics Reporting Implementation Guide (STU1)
This page is part of the Genetic Reporting Implementation Guide (v1.0.0: STU 1) based on FHIR R4. The current version which supercedes this version is 2.0.0. For a full list of available versions, see the Directory of published versions 
Turtle representation of the variant Profile.
@prefix fhir: <http://hl7.org/fhir/> . @prefix loinc: <http://loinc.org/rdf#> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- a fhir:StructureDefinition; fhir:nodeRole fhir:treeRoot; fhir:Resource.id [ fhir:value "variant"]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/formats.html#table\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/formats.html#table\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/formats.html#table\" title=\"Minimum and Maximum # of times the the element can appear in the instance\">Card.</a></th><th style=\"width: 100px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/formats.html#table\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/formats.html#table\" title=\"Additional information about the element\">Description & Constraints</a><span style=\"float: right\"><a href=\"https://hl7.org/fhir/formats.html#table\" title=\"Legend for this format\"><img src=\"https://hl7.org/fhir/help16.png\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation\" title=\"Details about a set of changes in the tested sample compared to a reference sequence.\">Observation</a><a name=\"Observation\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.4\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.4\">*</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.code\" title=\"Where testing scenarios are intended to assess the prescence or absence of a known set of DNA variants (e.g. tumor profiling using genotyping technology), then the Genetic Variant Assessment is used in conjunction with answer list supports structured communication of these findings. Of note, 'No Call' is different from 'Absent', because 'No Call' did not result in the determination of the marker's presents or absents. This may be due to test failure or specimen specific context which renders the test ineffective.\">code</a><a name=\"Observation.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genetic variant assessment<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck101.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">69548-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.value[x]\" title=\"Indicates whether the indicated variation was found or not.\">value[x]</a><a name=\"Observation.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Present|Absent|No call|Indeterminate<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL1971-2.html\">LOINC Answer List LL1971-2</a> (<a href=\"https://hl7.org/fhir/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.method\" title=\"Indicates the method of variant analysis.\">method</a><a name=\"Observation.method\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Sequencing | Oligo aCGH | SNP array | BAC aCGH |Curated|+<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL4048-6.html\">LOINC Answer List LL4048-6</a> (<a href=\"https://hl7.org/fhir/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Definition\" class=\"hierarchy\"/> <a style=\"font-style: italic\" href=\"variant-definitions.html#Observation.component\">component</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-style: italic\"/><span style=\"opacity: 0.4; font-style: italic\">0</span><span style=\"opacity: 0.5; font-style: italic\">..</span><span style=\"opacity: 0.4; font-style: italic\">*</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"font-style: italic\" href=\"https://hl7.org/fhir/profiling.html#slicing\">(Slice Definition)</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold; font-style: italic\">Slice: </span><span style=\"font-style: italic\">Unordered, Open by pattern:code</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:dna-chg\" title=\"Slice dna-chg: Human Genome Variation Society (HGVS) nomenclature for a single DNA marker.\">component:dna-chg</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">DNA Change - Transcript (cHGVS)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:dna-chg.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48004-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:dna-chg.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Binding: </span><a href=\"valueset-hgvs.html\">HGVS</a> (<a href=\"https://hl7.org/fhir/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:dna-chg-type\" title=\"Slice dna-chg-type: Codified type for associated DNA Marker. DNA Marker's use the HGVS notation which implies the DNA Marker Type, but the concurrent use of this code will allow a standard and explicit type for technical and display convenience.\">component:dna-chg-type</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">DNA change type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:dna-chg-type.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48019-4</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:dna-chg-type.value[x]\" title=\"Type of DNA variation reported.\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Concepts in sequence ontology under SO:0002072 (see http://www.sequenceontology.org/browser/current_release/term/SO:0002072)<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"valueset-dna-change-type.html\">DNA Change Type</a> (<a href=\"https://hl7.org/fhir/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:functional-annotation\" title=\"Slice functional-annotation: Annotated changes to sequence features caused by this variant.\">component:functional-annotation</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Functional Annotation<br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:functional-annotation.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"tbd-codes.html\">http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">functional-annotation</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:functional-annotation.value[x]\" title=\"Changes to sequence features caused by this variant.\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Concepts in sequence ontology under SO:0001537 (see http://www.sequenceontology.org/browser/current_release/term/SO:0001537)<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"valueset-functional-annotation.html\">Functional Annotation</a> (<a href=\"https://hl7.org/fhir/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:variation-code\" title=\"Slice variation-code: This term is used to report the unique identifier of the simple variant found in this study.\">component:variation-code</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variation Code</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:variation-code.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81252-9</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:variation-code.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Binding: </span><a href=\"https://hl7.org/fhir/terminologies.html#unbound\">(unbound)</a> (<a href=\"https://hl7.org/fhir/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included.\">example</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:dbSNP-id\" title=\"Slice dbSNP-id: The unique identifier for the variant represented as a small nucleotide polymorphism (SNP). The dbSNP ID is used routinely as the base identifier in pharmacogenomics as well as arrCGH studies. For example, for the simple variant NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys), the dbSNP ID is 368949613. [http://www.ncbi.nlm.nih.gov/clinvar/variation/30880/].\">component:dbSNP-id</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">dbSNP ID</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:dbSNP-id.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81255-2</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:dbSNP-id.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Binding: </span><a href=\"https://hl7.org/fhir/terminologies.html#unbound\">(unbound)</a> (<a href=\"https://hl7.org/fhir/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included.\">example</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:genomic-dna-chg\" title=\"Slice genomic-dna-chg: The name of a structural variant reported using HGVS nomenclature.\">component:genomic-dna-chg</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">DNA Change - Genomic (gHGVS)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:genomic-dna-chg.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81290-9</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:genomic-dna-chg.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Binding: </span><a href=\"valueset-hgvs.html\">HGVS</a> (<a href=\"https://hl7.org/fhir/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:genomic-source-class\" title=\"Slice genomic-source-class: The genomic class of the specimen being analyzed: Germline for inherited genome, somatic for cancer genome, and prenatal for fetal genome.\">component:genomic-source-class</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic source class</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:genomic-source-class.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48002-0</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:genomic-source-class.value[x]\" title=\"MG_2_Genetic variant source.\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Germline | Somatic | Fetal | Likely germline | Likely somatic |Likely fetal | Unknown genomic origin | De novo<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL378-1.html\">LOINC Answer List LL378-1</a> (<a href=\"https://hl7.org/fhir/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:amino-acid-chg\" title=\"Slice amino-acid-chg: Human Genome Variation Society (HGVS) nomenclature for an amino acid sequence. This value is derivable from the DNA Marker value if available. It is provided for convenience. The use of the nomenclature must be extended to describe non-variations (aka. wild types) see samples for wild type examples.\">component:amino-acid-chg</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Amino acid change (pHGVS)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:amino-acid-chg.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48005-3</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:amino-acid-chg.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Binding: </span><a href=\"valueset-hgvs.html\">HGVS</a> (<a href=\"https://hl7.org/fhir/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:amino-acid-chg-type\" title=\"Slice amino-acid-chg-type: Codified type for associated Amino Acid Marker. Amino Acid Marker's use the HGVS notation which implies the Amino Acid Marker Type, but the concurrent use of this code will allow a standard and explicit type for technical and display convenience.\">component:amino-acid-chg-type</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Amino acid change type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:amino-acid-chg-type.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48006-1</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:amino-acid-chg-type.value[x]\" title=\"MG_4_Amino acid change type.\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Wild type | Deletion | Duplication | Frameshift | Initiating Methionine | Insertion | Insertion and Deletion | Missense | Silent | Stop Codon Mutation<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL380-7.html\">LOINC Answer List LL380-7</a> (<a href=\"https://hl7.org/fhir/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:transcript-ref-seq\" title=\"Slice transcript-ref-seq: This field carries the ID for the transcribed reference sequence, which is the part of the genomic reference sequence that is converted to messenger RNA (i.e., after the introns are removed).\">component:transcript-ref-seq</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Transcript reference sequence ID</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:transcript-ref-seq.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">51958-7</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:transcript-ref-seq.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Binding: </span><a href=\"https://hl7.org/fhir/terminologies.html#unbound\">(unbound)</a> (<a href=\"https://hl7.org/fhir/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included.\">example</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:genomic-ref-seq\" title=\"Slice genomic-ref-seq: This field carries the ID for the genomic reference sequence. The genomic reference sequence is a contiguous stretch of chromosome DNA that spans all of the exons of the gene and includes transcribed and non transcribed stretches. For this ID use either the NCBI genomic nucleotide RefSeq IDs with their version number (see: NCBI.NLM.NIH.Gov/RefSeq) or use the LRG identifiers, without transcript (t or p) extensions -- when they become available. (See- Report sponsored by GEN2PHEN at the European Bioinformatics Institute at Hinxton UK April 24-25, 2008).\rThe NCI RefSeq genomic IDs are distinguished by a prefix of"NG" for genes from the nuclear chromosomes and prefix of "NC" for genes from mitochondria. The LRG Identifiers have a prefix of "LRG_" Mitochondrial genes are not in the scope of LRG.\">component:genomic-ref-seq</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic reference sequence ID</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:genomic-ref-seq.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48013-7</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:genomic-ref-seq.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Binding: </span><a href=\"https://hl7.org/fhir/terminologies.html#unbound\">(unbound)</a> (<a href=\"https://hl7.org/fhir/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included.\">example</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:sample-allelic-frequency\" title=\"Slice sample-allelic-frequency: \">component:sample-allelic-frequency</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Sample Allelic Frequency</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:sample-allelic-frequency.code\" title=\"The fraction of all reads in a study sample at a given genomic locus that identify the allele (variant) in question.\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Sample Sample VAF<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81258-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0341.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:sample-allelic-frequency.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Quantity\">Quantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03410.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:sample-allelic-frequency.value[x].value\">value</a><a name=\"Observation.component.value_x_.value\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#decimal\">decimal</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03400.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:sample-allelic-frequency.value[x].system\">system</a><a name=\"Observation.component.value_x_.system\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/ucum.html\">http://unitsofmeasure.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:allelic-read-depth\" title=\"Slice allelic-read-depth: Specifies the number of reads that identified the allele in question whether it consists of one or a small sequence of contiguous nucleotides. Different methods and purposes require different numbers of reads to be acceptable. Often >400, sometimes as few as 2-4.\">component:allelic-read-depth</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Allelic read depth<br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:allelic-read-depth.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">82121-5</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:allelic-read-depth.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Quantity\">Quantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:allelic-state\" title=\"Slice allelic-state: The level of occurrence of a single DNA Marker within a set of chromosomes. Heterozygous indicates the DNA Marker is only present in one of the two genes contained in homologous chromosomes. Homozygous indicates the DNA Marker is present in both genes contained in homologous chromosomes. Hemizygous indicates the DNA Marker exists in the only single copy of a gene in a non-homologous chromosome (The male X and Y chromosome are non-homologous). Hemiplasmic indicates that the DNA Marker is present in some but not all of the copies of mitochondrial DNA. Homoplasmic indicates that the DNA Maker is present in all of the copies of mitochondrial DNA.\">component:allelic-state</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Allelic state</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:allelic-state.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">53034-5</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:allelic-state.value[x]\" title=\"The relationship between the alleles found at the same locus on different chromosomes.\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Heteroplasmic | Homoplasmic | Homozygous | Heterozygous | Hemizygous<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL381-5.html\">LOINC Answer List LL381-5</a> (<a href=\"https://hl7.org/fhir/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:copy-number\" title=\"Slice copy-number: The copy number of the large variant. In HGVS, this is the numeric value following the “X”. It is a unit-less value. Note that a copy number of 1 implies a deletion. The copy number can usually be inferred from the HGVS or ISCN fields.\">component:copy-number</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic structural variant copy number</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:copy-number.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">82155-3</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:copy-number.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Count\" title=\"Quantity\">Count</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:ref-allele\" title=\"Slice ref-allele: Reference values ("normal") examined within the Reference Sequence.\">component:ref-allele</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic ref allele</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:ref-allele.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">69547-8</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:ref-allele.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:alt-allele\" title=\"Slice alt-allele: The genomic alternate allele is the contiguous segment of DNA in the test sample that differs from the reference allele at the same location and thus defines a variant.\">component:alt-allele</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic alt allele</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:alt-allele.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">69551-0</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:alt-allele.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:coordinate-system\" title=\"Slice coordinate-system: Base number of coordinate system either 0-based, with inclusive start and exclusive end (called interval), or 1-based, with inclusive start and end. However, two versions of 1-based are in common use.These systems are HGVS 1-based (called variant method) and VCF 1-based (called alignment method). In general, HGVS recommends right-justification and VCF recommends left-justification. However, these systems further address questions such as wheather or not to place an insertion before or after the nucleotide, and, if always placed before the nucleotide, how to handle insertion after the end of the sequence. Additionally, the systems deal with handling boundary effects of numbers between features. For more details see the HGVS and VCF guides.\">component:coordinate-system</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Coordinate System</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:coordinate-system.code\" title=\"This captures the base numbering used to calculate base positions in the reported sequence information.\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">92822-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:coordinate-system.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0-based interval | 0-based character | 1-based character<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL5323-2.html\">LOINC Answer List LL5323-2</a> (<a href=\"https://hl7.org/fhir/terminologies.html#preferred\" title=\"Instances are encouraged to draw from the specified codes for interoperability purposes but are not required to do so to be considered conformant.\">preferred</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:exact-start-end\" title=\"Slice exact-start-end: This location is the first genomic position in the reference allele that contains a change from the reference allele. For example, for the simple variant NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys), the location is Chr3: 128906220 on Assembly GRCh38.\">component:exact-start-end</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Exact start-end</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:exact-start-end.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"tbd-codes.html\">http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">exact-start-end</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0341.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:exact-start-end.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Range\">Range</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03410.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:exact-start-end.value[x].low\">low</a><a name=\"Observation.component.value_x_.low\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#SimpleQuantity\" title=\"Quantity\">SimpleQuantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Exact Start</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03400.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:exact-start-end.value[x].high\" title=\"Optional since many representations (VCF, SPDI) only provide a single position.\">high</a><a name=\"Observation.component.value_x_.high\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#SimpleQuantity\" title=\"Quantity\">SimpleQuantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Exact End</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:variant-length\" title=\"Slice variant-length: Length of the structural variant, which information may be ascertained in some but not all types of structural variants.\">component:variant-length</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Structural variant length</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:variant-length.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81300-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:variant-length.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Count\" title=\"Quantity\">Count</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:outer-start-end\" title=\"Slice outer-start-end: The genomic coordinates of the widest genomic range in which the variant might reside.\">component:outer-start-end</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant outer start and end</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:outer-start-end.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"tbd-codes.html\">http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">outer-start-end</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0341.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:outer-start-end.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Range\">Range</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03410.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:outer-start-end.value[x].low\">low</a><a name=\"Observation.component.value_x_.low\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#SimpleQuantity\" title=\"Quantity\">SimpleQuantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03400.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:outer-start-end.value[x].high\">high</a><a name=\"Observation.component.value_x_.high\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#SimpleQuantity\" title=\"Quantity\">SimpleQuantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:inner-start-end\" title=\"Slice inner-start-end: The genomic coordinates of the narrowest genomic range in which the structural variant might reside.\">component:inner-start-end</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant inner start and end</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:inner-start-end.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"tbd-codes.html\">http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">inner-start-end</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0341.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:inner-start-end.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Range\">Range</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03410.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:inner-start-end.value[x].low\">low</a><a name=\"Observation.component.value_x_.low\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#SimpleQuantity\" title=\"Quantity\">SimpleQuantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03400.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:inner-start-end.value[x].high\">high</a><a name=\"Observation.component.value_x_.high\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#SimpleQuantity\" title=\"Quantity\">SimpleQuantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:chromosome-copy-number-change-type\" title=\"Slice chromosome-copy-number-change-type: The type of the chromosome copy number change.\">component:chromosome-copy-number-change-type</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Chromosome copy number change type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:chromosome-copy-number-change-type.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">62378-5</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:chromosome-copy-number-change-type.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Copy number gain | Copy number loss<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL1041-4.html\">LOINC Answer List LL1041-4</a> (<a href=\"https://hl7.org/fhir/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:arrCGH-ratio\" title=\"Slice arrCGH-ratio: todo.\">component:arrCGH-ratio</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Structural variant reported arrCGH [Ratio]</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:arrCGH-ratio.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81299-0</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:arrCGH-ratio.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#SimpleQuantity\" title=\"Quantity\">SimpleQuantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:complex-var-type\" title=\"Slice complex-var-type: The type of complex variant, for example, compound heterozygous or haplotype.\">component:complex-var-type</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Complex variant type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:complex-var-type.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81263-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:complex-var-type.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Compound heterozygous | Double heterozygous | Haplotype | Hemizygous<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL3999-1.html\">LOINC Answer List LL3999-1</a> (<a href=\"https://hl7.org/fhir/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:cytogenomic-nomenclature\" title=\"Slice cytogenomic-nomenclature: Fully describes a variant with a single code. Typically a large variant such as a mosaic, abnormal chromosome numbers, etc.\">component:cytogenomic-nomenclature</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Cytogenomic Nomenclature</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0351.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:cytogenomic-nomenclature.code\" title=\"ISCN is a syntax for describing cytogenetic findings, from classical karyotypes to details that can be observed with copy number methodologies. Using ISCN nomenclature is highly recommended for reporting structural variants.\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant ISCN<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck03501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"https://hl7.org/fhir/loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck035000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81291-7</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:cytogenomic-nomenclature.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Binding: </span><a href=\"https://hl7.org/fhir/terminologies.html#unbound\">(unbound)</a> (<a href=\"https://hl7.org/fhir/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included.\">example</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck025.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:variant-inheritance\" title=\"Slice variant-inheritance: \">component:variant-inheritance</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.4\" href=\"https://hl7.org/fhir/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant Inheritance</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0251.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:variant-inheritance.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck02501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck025010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"tbd-codes.html\">http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck025000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"https://hl7.org/fhir/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">variant-inheritance</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0240.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"variant-definitions.html#Observation.component:variant-inheritance.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://hl7.org/fhir/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"font-weight:bold\">Binding: </span><a href=\"valueset-variant-inheritance.html\">Variant Inheritance</a> (<a href=\"https://hl7.org/fhir/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"https://hl7.org/fhir/formats.html#table\" title=\"Legend for this format\"><img src=\"https://hl7.org/fhir/help16.png\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>" ]; fhir:StructureDefinition.url [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"]; fhir:StructureDefinition.version [ fhir:value "1.0.0"]; fhir:StructureDefinition.name [ fhir:value "Variant"]; fhir:StructureDefinition.title [ fhir:value "Variant"]; fhir:StructureDefinition.status [ fhir:value "draft"]; fhir:StructureDefinition.experimental [ fhir:value "false"^^xsd:boolean]; fhir:StructureDefinition.date [ fhir:value "2017-05-20T00:00:00-04:00"^^xsd:dateTime]; fhir:StructureDefinition.publisher [ fhir:value "HL7 Clinical Genomics WG"]; fhir:StructureDefinition.description [ fhir:value "Observation-related profiles"]; fhir:StructureDefinition.fhirVersion [ fhir:value "4.0.1"]; fhir:StructureDefinition.mapping [ fhir:index 0; fhir:StructureDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:StructureDefinition.mapping.uri [ fhir:value "http://unknown.org/V2-CG-Results" ]; fhir:StructureDefinition.mapping.name [ fhir:value "V2-CG-Results" ] ], [ fhir:index 1; fhir:StructureDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/fhir/workflow" ]; fhir:StructureDefinition.mapping.name [ fhir:value "Workflow Pattern" ] ], [ fhir:index 2; fhir:StructureDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:StructureDefinition.mapping.uri [ fhir:value "http://snomed.info/conceptdomain" ]; fhir:StructureDefinition.mapping.name [ fhir:value "SNOMED CT Concept Domain Binding" ] ], [ fhir:index 3; fhir:StructureDefinition.mapping.identity [ fhir:value "v2" ]; fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/v2" ]; fhir:StructureDefinition.mapping.name [ fhir:value "HL7 v2 Mapping" ] ], [ fhir:index 4; fhir:StructureDefinition.mapping.identity [ fhir:value "rim" ]; fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/v3" ]; fhir:StructureDefinition.mapping.name [ fhir:value "RIM Mapping" ] ], [ fhir:index 5; fhir:StructureDefinition.mapping.identity [ fhir:value "w5" ]; fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/fhir/fivews" ]; fhir:StructureDefinition.mapping.name [ fhir:value "FiveWs Pattern Mapping" ] ], [ fhir:index 6; fhir:StructureDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:StructureDefinition.mapping.uri [ fhir:value "http://snomed.org/attributebinding" ]; fhir:StructureDefinition.mapping.name [ fhir:value "SNOMED CT Attribute Binding" ] ]; fhir:StructureDefinition.kind [ fhir:value "resource"]; fhir:StructureDefinition.abstract [ fhir:value "false"^^xsd:boolean]; fhir:StructureDefinition.type [ fhir:value "Observation"]; fhir:StructureDefinition.baseDefinition [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding> ]; fhir:StructureDefinition.derivation [ fhir:value "constraint"]; fhir:StructureDefinition.snapshot [ fhir:StructureDefinition.snapshot.element [ fhir:index 0; fhir:Element.id [ fhir:value "Observation" ]; fhir:ElementDefinition.path [ fhir:value "Observation" ]; fhir:ElementDefinition.short [ fhir:value "Variant" ]; fhir:ElementDefinition.definition [ fhir:value "Details about a set of changes in the tested sample compared to a reference sequence." ]; fhir:ElementDefinition.comment [ fhir:value "This change can be simple/discrete (relatively short), structural (potentially very large), or complex (consisting of multiple independent co-occurring variations)." ]; fhir:ElementDefinition.alias [ fhir:value "Vital Signs"; fhir:index 0 ], [ fhir:value "Measurement"; fhir:index 1 ], [ fhir:value "Results"; fhir:index 2 ], [ fhir:value "Tests"; fhir:index 3 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "dom-2" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "If the resource is contained in another resource, it SHALL NOT contain nested Resources" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "contained.contained.empty()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(parent::f:contained and f:contained)" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource"; fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "dom-3" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource"; fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource> ] ], [ fhir:index 2; fhir:ElementDefinition.constraint.key [ fhir:value "dom-4" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource"; fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource> ] ], [ fhir:index 3; fhir:ElementDefinition.constraint.key [ fhir:value "dom-5" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "If a resource is contained in another resource, it SHALL NOT have a security label" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "contained.meta.security.empty()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:contained/*/f:meta/f:security))" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource"; fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource> ] ], [ fhir:index 4; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice" ]; fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ] ], [ fhir:index 1; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation" ]; fhir:Extension.valueMarkdown [ fhir:value "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time." ] ]; fhir:ElementDefinition.constraint.key [ fhir:value "dom-6" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "warning" ]; fhir:ElementDefinition.constraint.human [ fhir:value "A resource should have narrative for robust management" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "text.`div`.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:text/h:div)" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource"; fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource> ] ], [ fhir:index 5; fhir:ElementDefinition.constraint.key [ fhir:value "obs-6" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "dataAbsentReason SHALL only be present if Observation.value[x] is not present" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "dataAbsentReason.empty() or value.empty()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:dataAbsentReason)) or (not(exists(*[starts-with(local-name(.), 'value')])))" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation"; fhir:link <http://hl7.org/fhir/StructureDefinition/Observation> ] ], [ fhir:index 6; fhir:ElementDefinition.constraint.key [ fhir:value "obs-7" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "value.empty() or component.code.where(coding.intersect(%resource.code.coding).exists()).empty()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(f:*[starts-with(local-name(.), 'value')] and (for $coding in f:code/f:coding return f:component/f:code/f:coding[f:code/@value=$coding/f:code/@value] [f:system/@value=$coding/f:system/@value]))" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation"; fhir:link <http://hl7.org/fhir/StructureDefinition/Observation> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Entity. Role, or Act" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity|" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Observation[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 1; fhir:Element.id [ fhir:value "Observation.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.id" ]; fhir:ElementDefinition.short [ fhir:value "Logical id of this artifact" ]; fhir:ElementDefinition.definition [ fhir:value "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes." ]; fhir:ElementDefinition.comment [ fhir:value "The only time that a resource does not have an id is when it is being submitted to the server using a create operation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Resource.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ], [ fhir:index 2; fhir:Element.id [ fhir:value "Observation.meta" ]; fhir:ElementDefinition.path [ fhir:value "Observation.meta" ]; fhir:ElementDefinition.short [ fhir:value "Metadata about the resource" ]; fhir:ElementDefinition.definition [ fhir:value "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Resource.meta" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Meta" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ], [ fhir:index 3; fhir:Element.id [ fhir:value "Observation.implicitRules" ]; fhir:ElementDefinition.path [ fhir:value "Observation.implicitRules" ]; fhir:ElementDefinition.short [ fhir:value "A set of rules under which this content was created" ]; fhir:ElementDefinition.definition [ fhir:value "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc." ]; fhir:ElementDefinition.comment [ fhir:value "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Resource.implicitRules" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "uri" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ] ], [ fhir:index 4; fhir:Element.id [ fhir:value "Observation.language" ]; fhir:ElementDefinition.path [ fhir:value "Observation.language" ]; fhir:ElementDefinition.short [ fhir:value "Language of the resource content" ]; fhir:ElementDefinition.definition [ fhir:value "The base language in which the resource is written." ]; fhir:ElementDefinition.comment [ fhir:value "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute)." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Resource.language" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "code" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet" ]; fhir:Extension.valueCanonical [ fhir:value "http://hl7.org/fhir/ValueSet/all-languages"; fhir:link <http://hl7.org/fhir/ValueSet/all-languages> ] ], [ fhir:index 1; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "Language" ] ], [ fhir:index 2; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding" ]; fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ]; fhir:ElementDefinition.binding.description [ fhir:value "A human language." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/languages"; fhir:link <http://hl7.org/fhir/ValueSet/languages> ] ] ], [ fhir:index 5; fhir:Element.id [ fhir:value "Observation.text" ]; fhir:ElementDefinition.path [ fhir:value "Observation.text" ]; fhir:ElementDefinition.short [ fhir:value "Text summary of the resource, for human interpretation" ]; fhir:ElementDefinition.definition [ fhir:value "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety." ]; fhir:ElementDefinition.comment [ fhir:value "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later." ]; fhir:ElementDefinition.alias [ fhir:value "narrative"; fhir:index 0 ], [ fhir:value "html"; fhir:index 1 ], [ fhir:value "xhtml"; fhir:index 2 ], [ fhir:value "display"; fhir:index 3 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "DomainResource.text" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Narrative" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Act.text?" ] ] ], [ fhir:index 6; fhir:Element.id [ fhir:value "Observation.contained" ]; fhir:ElementDefinition.path [ fhir:value "Observation.contained" ]; fhir:ElementDefinition.short [ fhir:value "Contained, inline Resources" ]; fhir:ElementDefinition.definition [ fhir:value "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope." ]; fhir:ElementDefinition.comment [ fhir:value "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels." ]; fhir:ElementDefinition.alias [ fhir:value "inline resources"; fhir:index 0 ], [ fhir:value "anonymous resources"; fhir:index 1 ], [ fhir:value "contained resources"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "DomainResource.contained" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Resource" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 7; fhir:Element.id [ fhir:value "Observation.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.extension" ]; fhir:ElementDefinition.slicing [ fhir:ElementDefinition.slicing.discriminator [ fhir:index 0; fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ]; fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ] ]; fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.slicing.rules [ fhir:value "open" ] ]; fhir:ElementDefinition.short [ fhir:value "Extension" ]; fhir:ElementDefinition.definition [ fhir:value "An Extension" ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "DomainResource.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 8; fhir:Element.id [ fhir:value "Observation.extension:BodyStructure" ]; fhir:ElementDefinition.path [ fhir:value "Observation.extension" ]; fhir:ElementDefinition.sliceName [ fhir:value "BodyStructure" ]; fhir:ElementDefinition.short [ fhir:value "Target anatomic location or structure" ]; fhir:ElementDefinition.definition [ fhir:value "Allows associating observations to a particular portion of the patient - a fetus, a tumor, a lesion, etc." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "DomainResource.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/bodySite"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/bodySite> ] ]; fhir:ElementDefinition.condition [ fhir:value "ele-1"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 9; fhir:Element.id [ fhir:value "Observation.extension:SecondaryFinding" ]; fhir:ElementDefinition.path [ fhir:value "Observation.extension" ]; fhir:ElementDefinition.sliceName [ fhir:value "SecondaryFinding" ]; fhir:ElementDefinition.short [ fhir:value "Secondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when [Whole Exome Sequencing (WES)](https://en.wikipedia.org/wiki/Exome_sequencing) or [Whole Genome Sequencing (WGS)](https://en.wikipedia.org/wiki/Whole_genome_sequencing) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement.\n\nFor more detail, please see:\nhttps://ghr.nlm.nih.gov/primer/testing/secondaryfindings" ]; fhir:ElementDefinition.definition [ fhir:value "Allows flagging observations that should be considered secondary findings." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "DomainResource.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding> ] ]; fhir:ElementDefinition.condition [ fhir:value "ele-1"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 10; fhir:Element.id [ fhir:value "Observation.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "DomainResource.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 11; fhir:Element.id [ fhir:value "Observation.identifier" ]; fhir:ElementDefinition.path [ fhir:value "Observation.identifier" ]; fhir:ElementDefinition.short [ fhir:value "Business Identifier for observation" ]; fhir:ElementDefinition.definition [ fhir:value "A unique identifier assigned to this observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Allows observations to be distinguished and referenced." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.identifier" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Identifier" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.identifier" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.identifier" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.21 For OBX segments from systems without OBX-21 support a combination of ORC/OBR and OBX must be negotiated between trading partners to uniquely identify the OBX segment. Depending on how V2 has been implemented each of these may be an option: 1) OBR-3 + OBX-3 + OBX-4 or 2) OBR-3 + OBR-4 + OBX-3 + OBX-4 or 2) some other way to uniquely ID the OBR/ORC + OBX-3 + OBX-4." ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "id" ] ] ], [ fhir:index 12; fhir:Element.id [ fhir:value "Observation.basedOn" ]; fhir:ElementDefinition.path [ fhir:value "Observation.basedOn" ]; fhir:ElementDefinition.short [ fhir:value "Fulfills plan, proposal or order" ]; fhir:ElementDefinition.definition [ fhir:value "A plan, proposal or order that is fulfilled in whole or in part by this event. For example, a MedicationRequest may require a patient to have laboratory test performed before it is dispensed." ]; fhir:ElementDefinition.requirements [ fhir:value "Allows tracing of authorization for the event and tracking whether proposals/recommendations were acted upon." ]; fhir:ElementDefinition.alias [ fhir:value "Fulfills"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.basedOn" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/CarePlan"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/CarePlan> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/DeviceRequest"; fhir:index 1; fhir:link <http://hl7.org/fhir/StructureDefinition/DeviceRequest> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/ImmunizationRecommendation"; fhir:index 2; fhir:link <http://hl7.org/fhir/StructureDefinition/ImmunizationRecommendation> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationRequest"; fhir:index 3; fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationRequest> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/NutritionOrder"; fhir:index 4; fhir:link <http://hl7.org/fhir/StructureDefinition/NutritionOrder> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/ServiceRequest"; fhir:index 5; fhir:link <http://hl7.org/fhir/StructureDefinition/ServiceRequest> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.basedOn" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "ORC" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value ".inboundRelationship[typeCode=COMP].source[moodCode=EVN]" ] ] ], [ fhir:index 13; fhir:Element.id [ fhir:value "Observation.partOf" ]; fhir:ElementDefinition.path [ fhir:value "Observation.partOf" ]; fhir:ElementDefinition.short [ fhir:value "Part of referenced event" ]; fhir:ElementDefinition.definition [ fhir:value "A larger event of which this particular Observation is a component or step. For example, an observation as part of a procedure." ]; fhir:ElementDefinition.comment [ fhir:value "To link an Observation to an Encounter use `encounter`. See the [Notes](https://hl7.org/fhir/observation.html#obsgrouping) below for guidance on referencing another Observation." ]; fhir:ElementDefinition.alias [ fhir:value "Container"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.partOf" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationAdministration"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationAdministration> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationDispense"; fhir:index 1; fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationDispense> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationStatement"; fhir:index 2; fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationStatement> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/Procedure"; fhir:index 3; fhir:link <http://hl7.org/fhir/StructureDefinition/Procedure> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/Immunization"; fhir:index 4; fhir:link <http://hl7.org/fhir/StructureDefinition/Immunization> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/ImagingStudy"; fhir:index 5; fhir:link <http://hl7.org/fhir/StructureDefinition/ImagingStudy> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.partOf" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Varies by domain" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value ".outboundRelationship[typeCode=FLFS].target" ] ] ], [ fhir:index 14; fhir:Element.id [ fhir:value "Observation.status" ]; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-display-hint" ]; fhir:Extension.valueString [ fhir:value "default: final" ] ]; fhir:ElementDefinition.path [ fhir:value "Observation.status" ]; fhir:ElementDefinition.short [ fhir:value "registered | preliminary | final | amended +" ]; fhir:ElementDefinition.definition [ fhir:value "The status of the result value." ]; fhir:ElementDefinition.comment [ fhir:value "… This should generally be 'completed' or 'revised'." ]; fhir:ElementDefinition.requirements [ fhir:value "Need to track the status of individual results. Some results are finalized before the whole report is finalized." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.status" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "code" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "This element is labeled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationStatus" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes providing the status of an observation." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-status|4.0.1"; fhir:link <http://hl7.org/fhir/ValueSet/observation-status|4.0.1> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.status" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.status" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 445584004 |Report by finality status|" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-11" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "status Amended & Final are differentiated by whether it is the subject of a ControlAct event with a type of \"revise\"" ] ] ], [ fhir:index 15; fhir:Element.id [ fhir:value "Observation.category" ]; fhir:ElementDefinition.path [ fhir:value "Observation.category" ]; fhir:ElementDefinition.short [ fhir:value "Classification of type of observation" ]; fhir:ElementDefinition.definition [ fhir:value "A code that classifies the general type of observation being made." ]; fhir:ElementDefinition.comment [ fhir:value "… This should be populated with 'lab'." ]; fhir:ElementDefinition.requirements [ fhir:value "Used for filtering what observations are retrieved and displayed." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.category" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ]; fhir:Coding.code [ fhir:value "laboratory" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCategory" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes for high level observation categories." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-category"; fhir:link <http://hl7.org/fhir/ValueSet/observation-category> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.class" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value ".outboundRelationship[typeCode=\"COMP].target[classCode=\"LIST\", moodCode=\"EVN\"].code" ] ] ], [ fhir:index 16; fhir:Element.id [ fhir:value "Observation.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.code" ]; fhir:ElementDefinition.short [ fhir:value "Genetic variant assessment" ]; fhir:ElementDefinition.definition [ fhir:value "Where testing scenarios are intended to assess the prescence or absence of a known set of DNA variants (e.g. tumor profiling using genotyping technology), then the Genetic Variant Assessment is used in conjunction with answer list supports structured communication of these findings. Of note, 'No Call' is different from 'Absent', because 'No Call' did not result in the determination of the marker's presents or absents. This may be due to test failure or specimen specific context which renders the test ineffective." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and, if present, component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.alias [ fhir:value "Name"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69548-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69548-6" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.code" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR < 386053000 |Evaluation procedure|" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ], [ fhir:index 5; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "116680003 |Is a|" ] ] ], [ fhir:index 17; fhir:Element.id [ fhir:value "Observation.subject" ]; fhir:ElementDefinition.path [ fhir:value "Observation.subject" ]; fhir:ElementDefinition.short [ fhir:value "Who and/or what the observation is about" ]; fhir:ElementDefinition.definition [ fhir:value "The patient, or group of patients, location, or device this observation is about and into whose record the observation is placed. If the actual focus of the observation is different from the subject (or a sample of, part, or region of the subject), the `focus` element or the `code` itself specifies the actual focus of the observation." ]; fhir:ElementDefinition.comment [ fhir:value "… This must be the same patient as on the DiagnosticReport unless combining data from multiple fetuses or family members in a single report." ]; fhir:ElementDefinition.requirements [ fhir:value "Observations have no value if you don't know who or what they're about." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.subject" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Patient"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Patient> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/Group"; fhir:index 1; fhir:link <http://hl7.org/fhir/StructureDefinition/Group> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/Location"; fhir:index 2; fhir:link <http://hl7.org/fhir/StructureDefinition/Location> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.subject" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject[x]" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "PID-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=RTGT] " ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject" ] ] ], [ fhir:index 18; fhir:Element.id [ fhir:value "Observation.focus" ]; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status" ]; fhir:Extension.valueCode [ fhir:value "trial-use" ] ]; fhir:ElementDefinition.path [ fhir:value "Observation.focus" ]; fhir:ElementDefinition.short [ fhir:value "What the observation is about, when it is not about the subject of record" ]; fhir:ElementDefinition.definition [ fhir:value "The actual focus of an observation when it is not the patient of record representing something or someone associated with the patient such as a spouse, parent, fetus, or donor. For example, fetus observations in a mother's record. The focus of an observation could also be an existing condition, an intervention, the subject's diet, another observation of the subject, or a body structure such as tumor or implanted device. An example use case would be using the Observation resource to capture whether the mother is trained to change her child's tracheostomy tube. In this example, the child is the patient of record and the mother is the focus." ]; fhir:ElementDefinition.comment [ fhir:value "Typically, an observation is made about the subject - a patient, or group of patients, location, or device - and the distinction between the subject and what is directly measured for an observation is specified in the observation code itself ( e.g., \"Blood Glucose\") and does not need to be represented separately using this element. Use `specimen` if a reference to a specimen is required. If a code is required instead of a resource use either `bodysite` for bodysites or the standard extension [focusCode](https://hl7.org/fhir/extension-observation-focuscode.html)." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.focus" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Resource"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Resource> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=SBJ]" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject" ] ] ], [ fhir:index 19; fhir:Element.id [ fhir:value "Observation.encounter" ]; fhir:ElementDefinition.path [ fhir:value "Observation.encounter" ]; fhir:ElementDefinition.short [ fhir:value "Healthcare event during which this observation is made" ]; fhir:ElementDefinition.definition [ fhir:value "The healthcare event (e.g. a patient and healthcare provider interaction) during which this observation is made." ]; fhir:ElementDefinition.comment [ fhir:value "This will typically be the encounter the event occurred within, but some events may be initiated prior to or after the official completion of an encounter but still be tied to the context of the encounter (e.g. pre-admission laboratory tests)." ]; fhir:ElementDefinition.requirements [ fhir:value "For some observations it may be important to know the link between an observation and a particular encounter." ]; fhir:ElementDefinition.alias [ fhir:value "Context"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.encounter" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Encounter"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Encounter> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.context" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.context" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "PV1" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN]" ] ] ], [ fhir:index 20; fhir:Element.id [ fhir:value "Observation.effective[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.effective[x]" ]; fhir:ElementDefinition.slicing [ fhir:ElementDefinition.slicing.discriminator [ fhir:index 0; fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "type" ]; fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "$this" ] ]; fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.slicing.rules [ fhir:value "closed" ] ]; fhir:ElementDefinition.short [ fhir:value "Clinically relevant time/time-period for observation" ]; fhir:ElementDefinition.definition [ fhir:value "The time or time-period the observed value is asserted as being true. For biological subjects - e.g. human patients - this is usually called the \"physiologically relevant time\". This is usually either the time of the procedure or of specimen collection, but very often the source of the date/time is not known, only the date/time itself." ]; fhir:ElementDefinition.comment [ fhir:value "At least a date should be present unless this observation is a historical report. For recording imprecise or \"fuzzy\" times (For example, a blood glucose measurement taken \"after breakfast\") use the [Timing](https://hl7.org/fhir/datatypes.html#timing) datatype which allow the measurement to be tied to regular life events." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing when an observation was deemed true is important to its relevance as well as determining trends." ]; fhir:ElementDefinition.alias [ fhir:value "Occurrence"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.effective[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "dateTime" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.occurrence[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.done[x]" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-14, and/or OBX-19 after v2.4 (depends on who observation made)" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "effectiveTime" ] ] ], [ fhir:index 21; fhir:Element.id [ fhir:value "Observation.effective[x]:effectiveDateTime" ]; fhir:ElementDefinition.path [ fhir:value "Observation.effective[x]" ]; fhir:ElementDefinition.sliceName [ fhir:value "effectiveDateTime" ]; fhir:ElementDefinition.short [ fhir:value "Clinically relevant time/time-period for observation" ]; fhir:ElementDefinition.definition [ fhir:value "The time or time-period the observed value is asserted as being true. For biological subjects - e.g. human patients - this is usually called the \"physiologically relevant time\". This is usually either the time of the procedure or of specimen collection, but very often the source of the date/time is not known, only the date/time itself." ]; fhir:ElementDefinition.comment [ fhir:value "At least a date should be present unless this observation is a historical report. For recording imprecise or \"fuzzy\" times (For example, a blood glucose measurement taken \"after breakfast\") use the [Timing](https://hl7.org/fhir/datatypes.html#timing) datatype which allow the measurement to be tied to regular life events." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing when an observation was deemed true is important to its relevance as well as determining trends." ]; fhir:ElementDefinition.alias [ fhir:value "Occurrence"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.effective[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "dateTime" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.occurrence[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.done[x]" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-14, and/or OBX-19 after v2.4 (depends on who observation made)" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "effectiveTime" ] ] ], [ fhir:index 22; fhir:Element.id [ fhir:value "Observation.issued" ]; fhir:ElementDefinition.path [ fhir:value "Observation.issued" ]; fhir:ElementDefinition.short [ fhir:value "Date/Time this version was made available" ]; fhir:ElementDefinition.definition [ fhir:value "The date and time this version of the observation was made available to providers, typically after the results have been reviewed and verified." ]; fhir:ElementDefinition.comment [ fhir:value "For Observations that don’t require review and verification, it may be the same as the [`lastUpdated` ](https://hl7.org/fhir/resource-definitions.html#Meta.lastUpdated) time of the resource itself. For Observations that do require review and verification for certain updates, it might not be the same as the `lastUpdated` time of the resource itself due to a non-clinically significant update that doesn’t require the new version to be reviewed and verified again." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.issued" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "instant" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.recorded" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBR.22 (or MSH.7), or perhaps OBX-19 (depends on who observation made)" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=AUT].time" ] ] ], [ fhir:index 23; fhir:Element.id [ fhir:value "Observation.performer" ]; fhir:ElementDefinition.path [ fhir:value "Observation.performer" ]; fhir:ElementDefinition.short [ fhir:value "Who is responsible for the observation" ]; fhir:ElementDefinition.definition [ fhir:value "Who was responsible for asserting the observed value as \"true\"." ]; fhir:ElementDefinition.requirements [ fhir:value "May give a degree of confidence in the observation and also indicates where follow-up questions should be directed." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.performer" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Practitioner"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Practitioner> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/Organization"; fhir:index 1; fhir:link <http://hl7.org/fhir/StructureDefinition/Organization> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/Patient"; fhir:index 2; fhir:link <http://hl7.org/fhir/StructureDefinition/Patient> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/RelatedPerson"; fhir:index 3; fhir:link <http://hl7.org/fhir/StructureDefinition/RelatedPerson> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Event.performer.actor" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.actor" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.15 / (Practitioner) OBX-16, PRT-5:PRT-4='RO' / (Device) OBX-18 , PRT-10:PRT-4='EQUIP' / (Organization) OBX-23, PRT-8:PRT-4='PO'" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=PRF]" ] ] ], [ fhir:index 24; fhir:Element.id [ fhir:value "Observation.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Present|Absent|No call|Indeterminate" ]; fhir:ElementDefinition.definition [ fhir:value "Indicates whether the indicated variation was found or not." ]; fhir:ElementDefinition.comment [ fhir:value "If not searching for specific variations and merely reporting what's found, this element should be set to \"Present\"." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-7"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "Genetic Variant Assessment" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL1971-2"; fhir:link <http://loinc.org/vs/LL1971-2> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.21" ] ] ], [ fhir:index 25; fhir:Element.id [ fhir:value "Observation.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "Null or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"specimen unsatisfactory\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Note that an observation may only be reported if there are values to report. For example differential cell counts values may be reported only when > 0. Because of these options, use-case agreements are required to interpret general observations for null or exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 26; fhir:Element.id [ fhir:value "Observation.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 27; fhir:Element.id [ fhir:value "Observation.note" ]; fhir:ElementDefinition.path [ fhir:value "Observation.note" ]; fhir:ElementDefinition.short [ fhir:value "Comments about the observation" ]; fhir:ElementDefinition.definition [ fhir:value "Comments about the observation or the results." ]; fhir:ElementDefinition.comment [ fhir:value "May include general statements about the observation, or statements about significant, unexpected or unreliable results values, or information about its source when relevant to its interpretation." ]; fhir:ElementDefinition.requirements [ fhir:value "Need to be able to provide free text additional information." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.note" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Annotation" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "NTE.3 (partner NTE to OBX, or sometimes another (child?) OBX)" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "subjectOf.observationEvent[code=\"annotation\"].value" ] ] ], [ fhir:index 28; fhir:Element.id [ fhir:value "Observation.bodySite" ]; fhir:ElementDefinition.path [ fhir:value "Observation.bodySite" ]; fhir:ElementDefinition.short [ fhir:value "Observed body part" ]; fhir:ElementDefinition.definition [ fhir:value "Indicates the site on the subject's body where the observation was made (i.e. the target site)." ]; fhir:ElementDefinition.comment [ fhir:value "Only used if not implicit in code found in Observation.code. In many systems, this may be represented as a related observation instead of an inline component. \n\nIf the use case requires BodySite to be handled as a separate resource (e.g. to identify and track separately) then use the standard extension[ bodySite](https://hl7.org/fhir/extension-bodysite.html)." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.bodySite" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "BodySite" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes describing anatomical locations. May include laterality." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/body-site"; fhir:link <http://hl7.org/fhir/ValueSet/body-site> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 123037004 |Body structure|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-20" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "targetSiteCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "718497002 |Inherent location|" ] ] ], [ fhir:index 29; fhir:Element.id [ fhir:value "Observation.method" ]; fhir:ElementDefinition.path [ fhir:value "Observation.method" ]; fhir:ElementDefinition.short [ fhir:value "Sequencing | Oligo aCGH | SNP array | BAC aCGH |Curated|+" ]; fhir:ElementDefinition.definition [ fhir:value "Indicates the method of variant analysis." ]; fhir:ElementDefinition.comment [ fhir:value "Only used if not implicit in code for Observation.code." ]; fhir:ElementDefinition.requirements [ fhir:value "In some cases, method can impact results and is thus used for determining whether results can be compared or determining significance of results." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.method" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Variant analysis method type" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL4048-6"; fhir:link <http://loinc.org/vs/LL4048-6> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-17" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "methodCode" ] ] ], [ fhir:index 30; fhir:Element.id [ fhir:value "Observation.specimen" ]; fhir:ElementDefinition.path [ fhir:value "Observation.specimen" ]; fhir:ElementDefinition.short [ fhir:value "Specimen examined" ]; fhir:ElementDefinition.definition [ fhir:value "The specimen examined to determine genetic information." ]; fhir:ElementDefinition.comment [ fhir:value "Should only be used if not implicit in code found in `Observation.code`. Observations are not made on specimens themselves; they are made on a subject, but in many cases by the means of a specimen. Note that although specimens are often involved, they are not always tracked and reported explicitly. Also note that observation resources may be used in contexts that track the specimen explicitly (e.g. Diagnostic Report)." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.specimen" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Specimen"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Specimen> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 123038009 |Specimen|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "SPM segment" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=SPC].specimen" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "704319004 |Inherent in|" ] ] ], [ fhir:index 31; fhir:Element.id [ fhir:value "Observation.device" ]; fhir:ElementDefinition.path [ fhir:value "Observation.device" ]; fhir:ElementDefinition.short [ fhir:value "(Measurement) Device" ]; fhir:ElementDefinition.definition [ fhir:value "The device used to generate the observation data." ]; fhir:ElementDefinition.comment [ fhir:value "Note that this is not meant to represent a device involved in the transmission of the result, e.g., a gateway. Such devices may be documented using the Provenance resource where relevant." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.device" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Device"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Device> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/DeviceMetric"; fhir:index 1; fhir:link <http://hl7.org/fhir/StructureDefinition/DeviceMetric> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 49062001 |Device|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-17 / PRT -10" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=DEV]" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "424226004 |Using device|" ] ] ], [ fhir:index 32; fhir:Element.id [ fhir:value "Observation.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range. Multiple reference ranges are interpreted as an \"OR\". In other words, to represent two distinct target populations, two `referenceRange` elements would be used." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "obs-3" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have at least a low or a high or text" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "low.exists() or high.exists() or text.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "(exists(f:low) or exists(f:high)or exists(f:text))" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 33; fhir:Element.id [ fhir:value "Observation.referenceRange.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 34; fhir:Element.id [ fhir:value "Observation.referenceRange.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 35; fhir:Element.id [ fhir:value "Observation.referenceRange.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 36; fhir:Element.id [ fhir:value "Observation.referenceRange.low" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.low" ]; fhir:ElementDefinition.short [ fhir:value "Low Range, if relevant" ]; fhir:ElementDefinition.definition [ fhir:value "The value of the low bound of the reference range. The low bound of the reference range endpoint is inclusive of the value (e.g. reference range is >=5 - <=9). If the low bound is omitted, it is assumed to be meaningless (e.g. reference range is <=2.3)." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.low" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-3"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value:IVL_PQ.low" ] ] ], [ fhir:index 37; fhir:Element.id [ fhir:value "Observation.referenceRange.high" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.high" ]; fhir:ElementDefinition.short [ fhir:value "High Range, if relevant" ]; fhir:ElementDefinition.definition [ fhir:value "The value of the high bound of the reference range. The high bound of the reference range endpoint is inclusive of the value (e.g. reference range is >=5 - <=9). If the high bound is omitted, it is assumed to be meaningless (e.g. reference range is >= 2.3)." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.high" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-3"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value:IVL_PQ.high" ] ] ], [ fhir:index 38; fhir:Element.id [ fhir:value "Observation.referenceRange.type" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.type" ]; fhir:ElementDefinition.short [ fhir:value "Reference range qualifier" ]; fhir:ElementDefinition.definition [ fhir:value "Codes to indicate the what part of the targeted reference population it applies to. For example, the normal or therapeutic range." ]; fhir:ElementDefinition.comment [ fhir:value "This SHOULD be populated if there is more than one range. If this element is not present then the normal range is assumed." ]; fhir:ElementDefinition.requirements [ fhir:value "Need to be able to say what kind of reference range this is - normal, recommended, therapeutic, etc., - for proper interpretation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.type" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationRangeMeaning" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ]; fhir:ElementDefinition.binding.description [ fhir:value "Code for the meaning of a reference range." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/referencerange-meaning"; fhir:link <http://hl7.org/fhir/ValueSet/referencerange-meaning> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values| OR \r< 365860008 |General clinical state finding| \rOR \r< 250171008 |Clinical history or observation findings| OR \r< 415229000 |Racial group| OR \r< 365400002 |Finding of puberty stage| OR\r< 443938003 |Procedure carried out on subject|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-10" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ] ], [ fhir:index 39; fhir:Element.id [ fhir:value "Observation.referenceRange.appliesTo" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.appliesTo" ]; fhir:ElementDefinition.short [ fhir:value "Reference range population" ]; fhir:ElementDefinition.definition [ fhir:value "Codes to indicate the target population this reference range applies to. For example, a reference range may be based on the normal population or a particular sex or race. Multiple `appliesTo` are interpreted as an \"AND\" of the target populations. For example, to represent a target population of African American females, both a code of female and a code for African American would be used." ]; fhir:ElementDefinition.comment [ fhir:value "This SHOULD be populated if there is more than one range. If this element is not present then the normal population is assumed." ]; fhir:ElementDefinition.requirements [ fhir:value "Need to be able to identify the target population for proper interpretation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.appliesTo" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationRangeType" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying the population the reference range applies to." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/referencerange-appliesto"; fhir:link <http://hl7.org/fhir/ValueSet/referencerange-appliesto> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values| OR \r< 365860008 |General clinical state finding| \rOR \r< 250171008 |Clinical history or observation findings| OR \r< 415229000 |Racial group| OR \r< 365400002 |Finding of puberty stage| OR\r< 443938003 |Procedure carried out on subject|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-10" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ] ], [ fhir:index 40; fhir:Element.id [ fhir:value "Observation.referenceRange.age" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.age" ]; fhir:ElementDefinition.short [ fhir:value "Applicable age range, if relevant" ]; fhir:ElementDefinition.definition [ fhir:value "The age at which this reference range is applicable. This is a neonatal age (e.g. number of weeks at term) if the meaning says so." ]; fhir:ElementDefinition.requirements [ fhir:value "Some analytes vary greatly over age." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.age" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Range" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=PRCN].targetObservationCriterion[code=\"age\"].value" ] ] ], [ fhir:index 41; fhir:Element.id [ fhir:value "Observation.referenceRange.text" ]; fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.text" ]; fhir:ElementDefinition.short [ fhir:value "Text based reference range in an observation" ]; fhir:ElementDefinition.definition [ fhir:value "Text based reference range in an observation which may be used when a quantitative range is not appropriate for an observation. An example would be a reference value of \"Negative\" or a list or table of \"normals\"." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.text" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "string" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value:ST" ] ] ], [ fhir:index 42; fhir:Element.id [ fhir:value "Observation.hasMember" ]; fhir:ElementDefinition.path [ fhir:value "Observation.hasMember" ]; fhir:ElementDefinition.short [ fhir:value "Related resource that belongs to the Observation group" ]; fhir:ElementDefinition.definition [ fhir:value "This observation is a group observation (e.g. a battery, a panel of tests, a set of vital sign measurements) that includes the target as a member of the group." ]; fhir:ElementDefinition.comment [ fhir:value "When using this element, an observation will typically have either a value or a set of related resources, although both may be present in some cases. For a discussion on the ways Observations can assembled in groups together, see [Notes](https://hl7.org/fhir/observation.html#obsgrouping) below. Note that a system may calculate results from [QuestionnaireResponse](https://hl7.org/fhir/questionnaireresponse.html) into a final score and represent the score as an Observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.hasMember" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Observation> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse"; fhir:index 1; fhir:link <http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/MolecularSequence"; fhir:index 2; fhir:link <http://hl7.org/fhir/StructureDefinition/MolecularSequence> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Relationships established by OBX-4 usage" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship" ] ] ], [ fhir:index 43; fhir:Element.id [ fhir:value "Observation.derivedFrom" ]; fhir:ElementDefinition.path [ fhir:value "Observation.derivedFrom" ]; fhir:ElementDefinition.short [ fhir:value "Related measurements the observation is made from" ]; fhir:ElementDefinition.definition [ fhir:value "The target resource that represents a measurement from which this observation value is derived. For example, a calculated anion gap or a fetal measurement based on an ultrasound image." ]; fhir:ElementDefinition.comment [ fhir:value "All the reference choices that are listed in this element can represent clinical observations and other measurements that may be the source for a derived value. The most common reference will be another Observation. For a discussion on the ways Observations can assembled in groups together, see [Notes](https://hl7.org/fhir/observation.html#obsgrouping) below." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.derivedFrom" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Reference" ]; fhir:ElementDefinition.type.targetProfile [ fhir:value "http://hl7.org/fhir/StructureDefinition/DocumentReference"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/DocumentReference> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/ImagingStudy"; fhir:index 1; fhir:link <http://hl7.org/fhir/StructureDefinition/ImagingStudy> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/Media"; fhir:index 2; fhir:link <http://hl7.org/fhir/StructureDefinition/Media> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse"; fhir:index 3; fhir:link <http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation"; fhir:index 4; fhir:link <http://hl7.org/fhir/StructureDefinition/Observation> ], [ fhir:value "http://hl7.org/fhir/StructureDefinition/MolecularSequence"; fhir:index 5; fhir:link <http://hl7.org/fhir/StructureDefinition/MolecularSequence> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "Relationships established by OBX-4 usage" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value ".targetObservation" ] ] ], [ fhir:index 44; fhir:Element.id [ fhir:value "Observation.component" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.slicing [ fhir:ElementDefinition.slicing.discriminator [ fhir:index 0; fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "pattern" ]; fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "code" ] ]; fhir:ElementDefinition.slicing.rules [ fhir:value "open" ] ]; fhir:ElementDefinition.short [ fhir:value "Component results" ]; fhir:ElementDefinition.definition [ fhir:value "Some observations have multiple component observations. These component observations are expressed as separate code value pairs that share the same attributes. Examples include systolic and diastolic component observations for blood pressure measurement and multiple component observations for genetics observations." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 45; fhir:Element.id [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 46; fhir:Element.id [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 47; fhir:Element.id [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 48; fhir:Element.id [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 49; fhir:Element.id [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ] ], [ fhir:index 1; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ], [ fhir:index 2; fhir:ElementDefinition.type.code [ fhir:value "string" ] ], [ fhir:index 3; fhir:ElementDefinition.type.code [ fhir:value "boolean" ] ], [ fhir:index 4; fhir:ElementDefinition.type.code [ fhir:value "integer" ] ], [ fhir:index 5; fhir:ElementDefinition.type.code [ fhir:value "Range" ] ], [ fhir:index 6; fhir:ElementDefinition.type.code [ fhir:value "Ratio" ] ], [ fhir:index 7; fhir:ElementDefinition.type.code [ fhir:value "SampledData" ] ], [ fhir:index 8; fhir:ElementDefinition.type.code [ fhir:value "time" ] ], [ fhir:index 9; fhir:ElementDefinition.type.code [ fhir:value "dateTime" ] ], [ fhir:index 10; fhir:ElementDefinition.type.code [ fhir:value "Period" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ] ], [ fhir:index 50; fhir:Element.id [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 51; fhir:Element.id [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 52; fhir:Element.id [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 53; fhir:Element.id [ fhir:value "Observation.component:gene-studied" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "gene-studied" ]; fhir:ElementDefinition.short [ fhir:value "Gene studied ID" ]; fhir:ElementDefinition.definition [ fhir:value "HUGO Gene Nomenclature Committee (HGNC) identifier for a gene. List the gene(s) examined in full or in part by the study. If the study addresses multiple genes, these can be recorded in multiple gene studied components . The required coding will use the HGNC gene symbol as the display text and HGNC gene ID as the code." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 54; fhir:Element.id [ fhir:value "Observation.component:gene-studied.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 55; fhir:Element.id [ fhir:value "Observation.component:gene-studied.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 56; fhir:Element.id [ fhir:value "Observation.component:gene-studied.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 57; fhir:Element.id [ fhir:value "Observation.component:gene-studied.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48018-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48018-6" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 58; fhir:Element.id [ fhir:value "Observation.component:gene-studied.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used." ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "HGNC: Human Gene Nomenclature Committee" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "A.4" ] ] ], [ fhir:index 59; fhir:Element.id [ fhir:value "Observation.component:gene-studied.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 60; fhir:Element.id [ fhir:value "Observation.component:gene-studied.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 61; fhir:Element.id [ fhir:value "Observation.component:gene-studied.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 62; fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "cytogenetic-location" ]; fhir:ElementDefinition.short [ fhir:value "Cytogenetic (chromosome) location" ]; fhir:ElementDefinition.definition [ fhir:value "Some observations have multiple component observations. These component observations are expressed as separate code value pairs that share the same attributes. Examples include systolic and diastolic component observations for blood pressure measurement and multiple component observations for genetics observations." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 63; fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 64; fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 65; fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 66; fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48001-2; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48001-2" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 67; fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.17" ] ] ], [ fhir:index 68; fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 69; fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 70; fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 71; fhir:Element.id [ fhir:value "Observation.component:ref-sequence-assembly" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "ref-sequence-assembly" ]; fhir:ElementDefinition.short [ fhir:value "Human reference sequence assembly version" ]; fhir:ElementDefinition.definition [ fhir:value "Some observations have multiple component observations. These component observations are expressed as separate code value pairs that share the same attributes. Examples include systolic and diastolic component observations for blood pressure measurement and multiple component observations for genetics observations." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 72; fhir:Element.id [ fhir:value "Observation.component:ref-sequence-assembly.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 73; fhir:Element.id [ fhir:value "Observation.component:ref-sequence-assembly.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 74; fhir:Element.id [ fhir:value "Observation.component:ref-sequence-assembly.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 75; fhir:Element.id [ fhir:value "Observation.component:ref-sequence-assembly.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:62374-4; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "62374-4" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 76; fhir:Element.id [ fhir:value "Observation.component:ref-sequence-assembly.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Human reference sequence NCBI build IDs" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL1040-6"; fhir:link <http://loinc.org/vs/LL1040-6> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ] ], [ fhir:index 77; fhir:Element.id [ fhir:value "Observation.component:ref-sequence-assembly.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 78; fhir:Element.id [ fhir:value "Observation.component:ref-sequence-assembly.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 79; fhir:Element.id [ fhir:value "Observation.component:ref-sequence-assembly.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 80; fhir:Element.id [ fhir:value "Observation.component:dna-chg" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "dna-chg" ]; fhir:ElementDefinition.short [ fhir:value "DNA Change - Transcript (cHGVS)" ]; fhir:ElementDefinition.definition [ fhir:value "Human Genome Variation Society (HGVS) nomenclature for a single DNA marker." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 81; fhir:Element.id [ fhir:value "Observation.component:dna-chg.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 82; fhir:Element.id [ fhir:value "Observation.component:dna-chg.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 83; fhir:Element.id [ fhir:value "Observation.component:dna-chg.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 84; fhir:Element.id [ fhir:value "Observation.component:dna-chg.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48004-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48004-6" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 85; fhir:Element.id [ fhir:value "Observation.component:dna-chg.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "HGVS: Sequence Variant Nomenclature from the Human Genome Variation Society" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.5 (includes A.13 in version)" ] ] ], [ fhir:index 86; fhir:Element.id [ fhir:value "Observation.component:dna-chg.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 87; fhir:Element.id [ fhir:value "Observation.component:dna-chg.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 88; fhir:Element.id [ fhir:value "Observation.component:dna-chg.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 89; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "dna-chg-type" ]; fhir:ElementDefinition.short [ fhir:value "DNA change type" ]; fhir:ElementDefinition.definition [ fhir:value "Codified type for associated DNA Marker. DNA Marker's use the HGVS notation which implies the DNA Marker Type, but the concurrent use of this code will allow a standard and explicit type for technical and display convenience." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 90; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 91; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 92; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 93; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48019-4; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48019-4" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 94; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Concepts in sequence ontology under SO:0002072 (see http://www.sequenceontology.org/browser/current_release/term/SO:0002072)" ]; fhir:ElementDefinition.definition [ fhir:value "Type of DNA variation reported." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "DNA Change type values (Sequence Ontology)" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.7" ] ] ], [ fhir:index 95; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 96; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 97; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 98; fhir:Element.id [ fhir:value "Observation.component:functional-annotation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "functional-annotation" ]; fhir:ElementDefinition.short [ fhir:value "Functional Annotation" ]; fhir:ElementDefinition.definition [ fhir:value "Annotated changes to sequence features caused by this variant." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 99; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 100; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 101; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 102; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "functional-annotation" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 103; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Concepts in sequence ontology under SO:0001537 (see http://www.sequenceontology.org/browser/current_release/term/SO:0001537)" ]; fhir:ElementDefinition.definition [ fhir:value "Changes to sequence features caused by this variant." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Functional Annotation (Sequence Ontology)" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-annotation"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-annotation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ] ], [ fhir:index 104; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 105; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 106; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 107; fhir:Element.id [ fhir:value "Observation.component:variation-code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "variation-code" ]; fhir:ElementDefinition.short [ fhir:value "Variation Code" ]; fhir:ElementDefinition.definition [ fhir:value "This term is used to report the unique identifier of the simple variant found in this study." ]; fhir:ElementDefinition.comment [ fhir:value "If this is present, the components can be omitted but they might be included to avoid a need to look up the information in a registry. Typically only one code would be present, though multiple codings expressing the variant in different code systems are possible." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 108; fhir:Element.id [ fhir:value "Observation.component:variation-code.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 109; fhir:Element.id [ fhir:value "Observation.component:variation-code.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 110; fhir:Element.id [ fhir:value "Observation.component:variation-code.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 111; fhir:Element.id [ fhir:value "Observation.component:variation-code.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81252-9; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81252-9" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 112; fhir:Element.id [ fhir:value "Observation.component:variation-code.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.2, B.16 (A.16 in coding.version)" ] ] ], [ fhir:index 113; fhir:Element.id [ fhir:value "Observation.component:variation-code.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 114; fhir:Element.id [ fhir:value "Observation.component:variation-code.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 115; fhir:Element.id [ fhir:value "Observation.component:variation-code.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 116; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "dbSNP-id" ]; fhir:ElementDefinition.short [ fhir:value "dbSNP ID" ]; fhir:ElementDefinition.definition [ fhir:value "The unique identifier for the variant represented as a small nucleotide polymorphism (SNP). The dbSNP ID is used routinely as the base identifier in pharmacogenomics as well as arrCGH studies. For example, for the simple variant NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys), the dbSNP ID is 368949613. [http://www.ncbi.nlm.nih.gov/clinvar/variation/30880/]." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 117; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 118; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 119; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 120; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81255-2; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81255-2" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 121; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.15 (includes A.14 in version)" ] ] ], [ fhir:index 122; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 123; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 124; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 125; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "genomic-dna-chg" ]; fhir:ElementDefinition.short [ fhir:value "DNA Change - Genomic (gHGVS)" ]; fhir:ElementDefinition.definition [ fhir:value "The name of a structural variant reported using HGVS nomenclature." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 126; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 127; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 128; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 129; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81290-9; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81290-9" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 130; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "HGVS: Sequence Variant Nomenclature from the Human Genome Variation Society" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.10 (includes A.13 in version)" ] ] ], [ fhir:index 131; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 132; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 133; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 134; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "genomic-source-class" ]; fhir:ElementDefinition.short [ fhir:value "Genomic source class" ]; fhir:ElementDefinition.definition [ fhir:value "The genomic class of the specimen being analyzed: Germline for inherited genome, somatic for cancer genome, and prenatal for fetal genome." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 135; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 136; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 137; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 138; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48002-0; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48002-0" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 139; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Germline | Somatic | Fetal | Likely germline | Likely somatic |Likely fetal | Unknown genomic origin | De novo" ]; fhir:ElementDefinition.definition [ fhir:value "MG_2_Genetic variant source." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Genomic source class values" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL378-1"; fhir:link <http://loinc.org/vs/LL378-1> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.18" ] ] ], [ fhir:index 140; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 141; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 142; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 143; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "amino-acid-chg" ]; fhir:ElementDefinition.short [ fhir:value "Amino acid change (pHGVS)" ]; fhir:ElementDefinition.definition [ fhir:value "Human Genome Variation Society (HGVS) nomenclature for an amino acid sequence. This value is derivable from the DNA Marker value if available. It is provided for convenience. The use of the nomenclature must be extended to describe non-variations (aka. wild types) see samples for wild type examples." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 144; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 145; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 146; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 147; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48005-3; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48005-3" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 148; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "HGVS: Sequence Variant Nomenclature from the Human Genome Variation Society" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.6 (includes A.13 in version)" ] ] ], [ fhir:index 149; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 150; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 151; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 152; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "amino-acid-chg-type" ]; fhir:ElementDefinition.short [ fhir:value "Amino acid change type" ]; fhir:ElementDefinition.definition [ fhir:value "Codified type for associated Amino Acid Marker. Amino Acid Marker's use the HGVS notation which implies the Amino Acid Marker Type, but the concurrent use of this code will allow a standard and explicit type for technical and display convenience." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 153; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 154; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 155; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 156; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48006-1; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48006-1" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 157; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Wild type | Deletion | Duplication | Frameshift | Initiating Methionine | Insertion | Insertion and Deletion | Missense | Silent | Stop Codon Mutation" ]; fhir:ElementDefinition.definition [ fhir:value "MG_4_Amino acid change type." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "Amino acid change type values" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL380-7"; fhir:link <http://loinc.org/vs/LL380-7> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.8" ] ] ], [ fhir:index 158; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 159; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 160; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 161; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "transcript-ref-seq" ]; fhir:ElementDefinition.short [ fhir:value "Transcript reference sequence ID" ]; fhir:ElementDefinition.definition [ fhir:value "This field carries the ID for the transcribed reference sequence, which is the part of the genomic reference sequence that is converted to messenger RNA (i.e., after the introns are removed)." ]; fhir:ElementDefinition.comment [ fhir:value "Only needed if the transcript sequence or genomic reference sequence versions don't indicate the version." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 162; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 163; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 164; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 165; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:51958-7; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "51958-7" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 166; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.4" ] ] ], [ fhir:index 167; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 168; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 169; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 170; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "genomic-ref-seq" ]; fhir:ElementDefinition.short [ fhir:value "Genomic reference sequence ID" ]; fhir:ElementDefinition.definition [ fhir:value "This field carries the ID for the genomic reference sequence. The genomic reference sequence is a contiguous stretch of chromosome DNA that spans all of the exons of the gene and includes transcribed and non transcribed stretches. For this ID use either the NCBI genomic nucleotide RefSeq IDs with their version number (see: NCBI.NLM.NIH.Gov/RefSeq) or use the LRG identifiers, without transcript (t or p) extensions -- when they become available. (See- Report sponsored by GEN2PHEN at the European Bioinformatics Institute at Hinxton UK April 24-25, 2008).\rThe NCI RefSeq genomic IDs are distinguished by a prefix of\"NG\" for genes from the nuclear chromosomes and prefix of \"NC\" for genes from mitochondria. The LRG Identifiers have a prefix of \"LRG_\" Mitochondrial genes are not in the scope of LRG." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 171; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 172; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 173; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 174; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48013-7; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48013-7" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 175; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.9" ] ] ], [ fhir:index 176; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 177; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 178; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 179; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "sample-allelic-frequency" ]; fhir:ElementDefinition.short [ fhir:value "Sample Allelic Frequency" ]; fhir:ElementDefinition.definition [ fhir:value "Some observations have multiple component observations. These component observations are expressed as separate code value pairs that share the same attributes. Examples include systolic and diastolic component observations for blood pressure measurement and multiple component observations for genetics observations." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 180; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 181; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 182; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 183; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Sample Sample VAF" ]; fhir:ElementDefinition.definition [ fhir:value "The fraction of all reads in a study sample at a given genomic locus that identify the allele (variant) in question." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81258-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81258-6" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 184; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.22, C.4" ] ] ], [ fhir:index 185; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 186; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].extension" ]; fhir:ElementDefinition.slicing [ fhir:ElementDefinition.slicing.discriminator [ fhir:index 0; fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ]; fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ] ]; fhir:ElementDefinition.slicing.description [ fhir:value "Extensions are always sliced by (at least) url" ]; fhir:ElementDefinition.slicing.rules [ fhir:value "open" ] ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 187; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].value" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].value" ]; fhir:ElementDefinition.short [ fhir:value "Numerical value (with implicit precision)" ]; fhir:ElementDefinition.definition [ fhir:value "The value of the measured amount. The value includes an implicit precision in the presentation of the value." ]; fhir:ElementDefinition.comment [ fhir:value "The implicit precision in the value should always be honored. Monetary values have their own rules for handling precision (refer to standard accounting text books)." ]; fhir:ElementDefinition.requirements [ fhir:value "Precision is handled implicitly in almost all cases of measurement." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Quantity.value" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "decimal" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "SN.2 / CQ - N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "PQ.value, CO.value, MO.value, IVL.high or IVL.low depending on the value" ] ] ], [ fhir:index 188; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].comparator" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].comparator" ]; fhir:ElementDefinition.short [ fhir:value "< | <= | >= | > - how to understand the value" ]; fhir:ElementDefinition.definition [ fhir:value "How the value should be understood and represented - whether the actual value is greater or less than the stated value due to measurement issues; e.g. if the comparator is \"<\" , then the real value is < stated value." ]; fhir:ElementDefinition.requirements [ fhir:value "Need a framework for handling measures where the value is <5ug/L or >400mg/L due to the limitations of measuring methodology." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Quantity.comparator" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "code" ] ]; fhir:ElementDefinition.meaningWhenMissing [ fhir:value "If there is no comparator, then there is no modification of the value" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "This is labeled as \"Is Modifier\" because the comparator modifies the interpretation of the value significantly. If there is no comparator, then there is no modification of the value" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "QuantityComparator" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "How the Quantity should be understood and represented." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1"; fhir:link <http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "SN.1 / CQ.1" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "IVL properties" ] ] ], [ fhir:index 189; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].unit" ]; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable" ]; fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ] ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].unit" ]; fhir:ElementDefinition.short [ fhir:value "Unit representation" ]; fhir:ElementDefinition.definition [ fhir:value "A human-readable form of the unit." ]; fhir:ElementDefinition.requirements [ fhir:value "There are many representations for units of measure and in many contexts, particular representations are fixed and required. I.e. mcg for micrograms." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Quantity.unit" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "string" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "(see OBX.6 etc.) / CQ.2" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "PQ.unit" ] ] ], [ fhir:index 190; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].system" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].system" ]; fhir:ElementDefinition.short [ fhir:value "System that defines coded unit form" ]; fhir:ElementDefinition.definition [ fhir:value "The identification of the system that provides the coded form of the unit." ]; fhir:ElementDefinition.requirements [ fhir:value "Need to know the system that defines the coded form of the unit." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Quantity.system" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "uri" ] ]; fhir:ElementDefinition.fixedUri [ fhir:value "http://unitsofmeasure.org" ]; fhir:ElementDefinition.condition [ fhir:value "qty-3"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "(see OBX.6 etc.) / CQ.2" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "CO.codeSystem, PQ.translation.codeSystem" ] ] ], [ fhir:index 191; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].code" ]; fhir:ElementDefinition.short [ fhir:value "Coded form of the unit" ]; fhir:ElementDefinition.definition [ fhir:value "A computer processable form of the unit in some unit representation system." ]; fhir:ElementDefinition.comment [ fhir:value "The preferred system is UCUM, but SNOMED CT can also be used (for customary units) or ISO 4217 for currency. The context of use may additionally require a code from a particular system." ]; fhir:ElementDefinition.requirements [ fhir:value "Need a computable form of the unit that is fixed across all forms. UCUM provides this for quantities, but SNOMED CT provides many units of interest." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Quantity.code" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "code" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "(see OBX.6 etc.) / CQ.2" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "PQ.code, MO.currency, PQ.translation.code" ] ] ], [ fhir:index 192; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 193; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 194; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 195; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "allelic-read-depth" ]; fhir:ElementDefinition.short [ fhir:value "Allelic read depth" ]; fhir:ElementDefinition.definition [ fhir:value "Specifies the number of reads that identified the allele in question whether it consists of one or a small sequence of contiguous nucleotides. Different methods and purposes require different numbers of reads to be acceptable. Often >400, sometimes as few as 2-4." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 196; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 197; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 198; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 199; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:82121-5; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "82121-5" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 200; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.27, C.7" ] ] ], [ fhir:index 201; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 202; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 203; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 204; fhir:Element.id [ fhir:value "Observation.component:allelic-state" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "allelic-state" ]; fhir:ElementDefinition.short [ fhir:value "Allelic state" ]; fhir:ElementDefinition.definition [ fhir:value "The level of occurrence of a single DNA Marker within a set of chromosomes. Heterozygous indicates the DNA Marker is only present in one of the two genes contained in homologous chromosomes. Homozygous indicates the DNA Marker is present in both genes contained in homologous chromosomes. Hemizygous indicates the DNA Marker exists in the only single copy of a gene in a non-homologous chromosome (The male X and Y chromosome are non-homologous). Hemiplasmic indicates that the DNA Marker is present in some but not all of the copies of mitochondrial DNA. Homoplasmic indicates that the DNA Maker is present in all of the copies of mitochondrial DNA." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 205; fhir:Element.id [ fhir:value "Observation.component:allelic-state.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 206; fhir:Element.id [ fhir:value "Observation.component:allelic-state.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 207; fhir:Element.id [ fhir:value "Observation.component:allelic-state.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 208; fhir:Element.id [ fhir:value "Observation.component:allelic-state.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:53034-5; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "53034-5" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 209; fhir:Element.id [ fhir:value "Observation.component:allelic-state.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Heteroplasmic | Homoplasmic | Homozygous | Heterozygous | Hemizygous" ]; fhir:ElementDefinition.definition [ fhir:value "The relationship between the alleles found at the same locus on different chromosomes." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Allelic state type values" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL381-5"; fhir:link <http://loinc.org/vs/LL381-5> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.23, C.6" ] ] ], [ fhir:index 210; fhir:Element.id [ fhir:value "Observation.component:allelic-state.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 211; fhir:Element.id [ fhir:value "Observation.component:allelic-state.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 212; fhir:Element.id [ fhir:value "Observation.component:allelic-state.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 213; fhir:Element.id [ fhir:value "Observation.component:copy-number" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "copy-number" ]; fhir:ElementDefinition.short [ fhir:value "Genomic structural variant copy number" ]; fhir:ElementDefinition.definition [ fhir:value "The copy number of the large variant. In HGVS, this is the numeric value following the “X”. It is a unit-less value. Note that a copy number of 1 implies a deletion. The copy number can usually be inferred from the HGVS or ISCN fields." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 214; fhir:Element.id [ fhir:value "Observation.component:copy-number.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 215; fhir:Element.id [ fhir:value "Observation.component:copy-number.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 216; fhir:Element.id [ fhir:value "Observation.component:copy-number.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 217; fhir:Element.id [ fhir:value "Observation.component:copy-number.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:82155-3; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "82155-3" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 218; fhir:Element.id [ fhir:value "Observation.component:copy-number.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "A measured or measurable amount" ]; fhir:ElementDefinition.definition [ fhir:value "A measured amount (or an amount that can potentially be measured). Note that measured amounts include amounts that are not precisely quantified, including amounts involving arbitrary units and floating currencies." ]; fhir:ElementDefinition.comment [ fhir:value "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Count"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Count> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "cnt-3" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "There SHALL be a code with a value of \"1\" if there is a value. If system is present, it SHALL be UCUM. If present, the value SHALL be a whole number." ]; fhir:ElementDefinition.constraint.expression [ fhir:value "(code.exists() or value.empty()) and (system.empty() or system = %ucum) and (code.empty() or code = '1') and (value.empty() or value.hasValue().not() or value.toString().contains('.').not())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "(f:code or not(f:value)) and (not(exists(f:system)) or (f:system/@value='http://unitsofmeasure.org' and f:code/@value='1')) and not(contains(f:value/@value, '.'))" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 2; fhir:ElementDefinition.constraint.key [ fhir:value "qty-3" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "If a code for the unit is present, the system SHALL also be present" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "code.empty() or system.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:code)) or exists(f:system)" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Quantity"; fhir:link <http://hl7.org/fhir/StructureDefinition/Quantity> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "SN (see also Range) or CQ" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "PQ, IVL<PQ>, MO, CO, depending on the values" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.28" ] ] ], [ fhir:index 219; fhir:Element.id [ fhir:value "Observation.component:copy-number.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 220; fhir:Element.id [ fhir:value "Observation.component:copy-number.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 221; fhir:Element.id [ fhir:value "Observation.component:copy-number.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 222; fhir:Element.id [ fhir:value "Observation.component:ref-allele" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "ref-allele" ]; fhir:ElementDefinition.short [ fhir:value "Genomic ref allele" ]; fhir:ElementDefinition.definition [ fhir:value "Reference values (\"normal\") examined within the Reference Sequence." ]; fhir:ElementDefinition.comment [ fhir:value "This is used in a genotyping test to define the reference and variable nucleotide strings. That is if the sequence variation is an insertion, then Reference Nucleotide will be blank and Variable Nucleotide will contain the inserted nucleotides. In contrast, if the sequence variation is a deletion, then the Reference Nucleotide will contain the deleted nucliotieds, and the Variable Nucleotide will be blank." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.9" ] ] ], [ fhir:index 223; fhir:Element.id [ fhir:value "Observation.component:ref-allele.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 224; fhir:Element.id [ fhir:value "Observation.component:ref-allele.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 225; fhir:Element.id [ fhir:value "Observation.component:ref-allele.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 226; fhir:Element.id [ fhir:value "Observation.component:ref-allele.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69547-8; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69547-8" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 227; fhir:Element.id [ fhir:value "Observation.component:ref-allele.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "string" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ] ], [ fhir:index 228; fhir:Element.id [ fhir:value "Observation.component:ref-allele.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 229; fhir:Element.id [ fhir:value "Observation.component:ref-allele.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 230; fhir:Element.id [ fhir:value "Observation.component:ref-allele.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 231; fhir:Element.id [ fhir:value "Observation.component:alt-allele" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "alt-allele" ]; fhir:ElementDefinition.short [ fhir:value "Genomic alt allele" ]; fhir:ElementDefinition.definition [ fhir:value "The genomic alternate allele is the contiguous segment of DNA in the test sample that differs from the reference allele at the same location and thus defines a variant." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.11" ] ] ], [ fhir:index 232; fhir:Element.id [ fhir:value "Observation.component:alt-allele.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 233; fhir:Element.id [ fhir:value "Observation.component:alt-allele.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 234; fhir:Element.id [ fhir:value "Observation.component:alt-allele.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 235; fhir:Element.id [ fhir:value "Observation.component:alt-allele.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69551-0; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69551-0" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 236; fhir:Element.id [ fhir:value "Observation.component:alt-allele.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "string" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ] ], [ fhir:index 237; fhir:Element.id [ fhir:value "Observation.component:alt-allele.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 238; fhir:Element.id [ fhir:value "Observation.component:alt-allele.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 239; fhir:Element.id [ fhir:value "Observation.component:alt-allele.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 240; fhir:Element.id [ fhir:value "Observation.component:coordinate-system" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "coordinate-system" ]; fhir:ElementDefinition.short [ fhir:value "Coordinate System" ]; fhir:ElementDefinition.definition [ fhir:value "Base number of coordinate system either 0-based, with inclusive start and exclusive end (called interval), or 1-based, with inclusive start and end. However, two versions of 1-based are in common use.These systems are HGVS 1-based (called variant method) and VCF 1-based (called alignment method). In general, HGVS recommends right-justification and VCF recommends left-justification. However, these systems further address questions such as wheather or not to place an insertion before or after the nucleotide, and, if always placed before the nucleotide, how to handle insertion after the end of the sequence. Additionally, the systems deal with handling boundary effects of numbers between features. For more details see the HGVS and VCF guides." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 241; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 242; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 243; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 244; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "This captures the base numbering used to calculate base positions in the reported sequence information." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:92822-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "92822-6" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 245; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "0-based interval | 0-based character | 1-based character" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ]; fhir:ElementDefinition.binding.description [ fhir:value "Base coordinate systems start and end measurements for variants" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL5323-2"; fhir:link <http://loinc.org/vs/LL5323-2> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ] ], [ fhir:index 246; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 247; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 248; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 249; fhir:Element.id [ fhir:value "Observation.component:exact-start-end" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "exact-start-end" ]; fhir:ElementDefinition.short [ fhir:value "Exact start-end" ]; fhir:ElementDefinition.definition [ fhir:value "This location is the first genomic position in the reference allele that contains a change from the reference allele. For example, for the simple variant NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys), the location is Chr3: 128906220 on Assembly GRCh38." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.10" ] ] ], [ fhir:index 250; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 251; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 252; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 253; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "exact-start-end" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 254; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Range" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ] ], [ fhir:index 255; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x].id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 256; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x].extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].extension" ]; fhir:ElementDefinition.slicing [ fhir:ElementDefinition.slicing.discriminator [ fhir:index 0; fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ]; fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ] ]; fhir:ElementDefinition.slicing.description [ fhir:value "Extensions are always sliced by (at least) url" ]; fhir:ElementDefinition.slicing.rules [ fhir:value "open" ] ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 257; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x].low" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].low" ]; fhir:ElementDefinition.short [ fhir:value "Exact Start" ]; fhir:ElementDefinition.definition [ fhir:value "The low limit. The boundary is inclusive." ]; fhir:ElementDefinition.comment [ fhir:value "If the low element is missing, the low boundary is not known." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Range.low" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "NR.1" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "./low" ] ] ], [ fhir:index 258; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x].high" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].high" ]; fhir:ElementDefinition.short [ fhir:value "Exact End" ]; fhir:ElementDefinition.definition [ fhir:value "Optional since many representations (VCF, SPDI) only provide a single position." ]; fhir:ElementDefinition.comment [ fhir:value "If the high element is missing, the high boundary is not known." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Range.high" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "NR.2" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "./high" ] ] ], [ fhir:index 259; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 260; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 261; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 262; fhir:Element.id [ fhir:value "Observation.component:variant-length" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "variant-length" ]; fhir:ElementDefinition.short [ fhir:value "Structural variant length" ]; fhir:ElementDefinition.definition [ fhir:value "Length of the structural variant, which information may be ascertained in some but not all types of structural variants." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 263; fhir:Element.id [ fhir:value "Observation.component:variant-length.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 264; fhir:Element.id [ fhir:value "Observation.component:variant-length.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 265; fhir:Element.id [ fhir:value "Observation.component:variant-length.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 266; fhir:Element.id [ fhir:value "Observation.component:variant-length.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81300-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81300-6" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 267; fhir:Element.id [ fhir:value "Observation.component:variant-length.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "A measured or measurable amount" ]; fhir:ElementDefinition.definition [ fhir:value "A measured amount (or an amount that can potentially be measured). Note that measured amounts include amounts that are not precisely quantified, including amounts involving arbitrary units and floating currencies." ]; fhir:ElementDefinition.comment [ fhir:value "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Count"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Count> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "cnt-3" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "There SHALL be a code with a value of \"1\" if there is a value. If system is present, it SHALL be UCUM. If present, the value SHALL be a whole number." ]; fhir:ElementDefinition.constraint.expression [ fhir:value "(code.exists() or value.empty()) and (system.empty() or system = %ucum) and (code.empty() or code = '1') and (value.empty() or value.hasValue().not() or value.toString().contains('.').not())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "(f:code or not(f:value)) and (not(exists(f:system)) or (f:system/@value='http://unitsofmeasure.org' and f:code/@value='1')) and not(contains(f:value/@value, '.'))" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 2; fhir:ElementDefinition.constraint.key [ fhir:value "qty-3" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "If a code for the unit is present, the system SHALL also be present" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "code.empty() or system.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:code)) or exists(f:system)" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Quantity"; fhir:link <http://hl7.org/fhir/StructureDefinition/Quantity> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "SN (see also Range) or CQ" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "PQ, IVL<PQ>, MO, CO, depending on the values" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.30" ] ] ], [ fhir:index 268; fhir:Element.id [ fhir:value "Observation.component:variant-length.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 269; fhir:Element.id [ fhir:value "Observation.component:variant-length.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 270; fhir:Element.id [ fhir:value "Observation.component:variant-length.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 271; fhir:Element.id [ fhir:value "Observation.component:outer-start-end" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "outer-start-end" ]; fhir:ElementDefinition.short [ fhir:value "Variant outer start and end" ]; fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the widest genomic range in which the variant might reside." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 272; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 273; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 274; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 275; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "outer-start-end" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 276; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Range" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.31" ] ] ], [ fhir:index 277; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x].id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 278; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x].extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].extension" ]; fhir:ElementDefinition.slicing [ fhir:ElementDefinition.slicing.discriminator [ fhir:index 0; fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ]; fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ] ]; fhir:ElementDefinition.slicing.description [ fhir:value "Extensions are always sliced by (at least) url" ]; fhir:ElementDefinition.slicing.rules [ fhir:value "open" ] ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 279; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x].low" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].low" ]; fhir:ElementDefinition.short [ fhir:value "Low limit" ]; fhir:ElementDefinition.definition [ fhir:value "The low limit. The boundary is inclusive." ]; fhir:ElementDefinition.comment [ fhir:value "If the low element is missing, the low boundary is not known." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Range.low" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "NR.1" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "./low" ] ] ], [ fhir:index 280; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x].high" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].high" ]; fhir:ElementDefinition.short [ fhir:value "High limit" ]; fhir:ElementDefinition.definition [ fhir:value "The high limit. The boundary is inclusive." ]; fhir:ElementDefinition.comment [ fhir:value "If the high element is missing, the high boundary is not known." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Range.high" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "NR.2" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "./high" ] ] ], [ fhir:index 281; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 282; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 283; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 284; fhir:Element.id [ fhir:value "Observation.component:inner-start-end" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "inner-start-end" ]; fhir:ElementDefinition.short [ fhir:value "Variant inner start and end" ]; fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the narrowest genomic range in which the structural variant might reside." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 285; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 286; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 287; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 288; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "inner-start-end" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 289; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Range" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.32" ] ] ], [ fhir:index 290; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x].id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 291; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x].extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].extension" ]; fhir:ElementDefinition.slicing [ fhir:ElementDefinition.slicing.discriminator [ fhir:index 0; fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ]; fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ] ]; fhir:ElementDefinition.slicing.description [ fhir:value "Extensions are always sliced by (at least) url" ]; fhir:ElementDefinition.slicing.rules [ fhir:value "open" ] ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 292; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x].low" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].low" ]; fhir:ElementDefinition.short [ fhir:value "Low limit" ]; fhir:ElementDefinition.definition [ fhir:value "The low limit. The boundary is inclusive." ]; fhir:ElementDefinition.comment [ fhir:value "If the low element is missing, the low boundary is not known." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Range.low" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "NR.1" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "./low" ] ] ], [ fhir:index 293; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x].high" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].high" ]; fhir:ElementDefinition.short [ fhir:value "High limit" ]; fhir:ElementDefinition.definition [ fhir:value "The high limit. The boundary is inclusive." ]; fhir:ElementDefinition.comment [ fhir:value "If the high element is missing, the high boundary is not known." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Range.high" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "NR.2" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "./high" ] ] ], [ fhir:index 294; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 295; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 296; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 297; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "chromosome-copy-number-change-type" ]; fhir:ElementDefinition.short [ fhir:value "Chromosome copy number change type" ]; fhir:ElementDefinition.definition [ fhir:value "The type of the chromosome copy number change." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 298; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 299; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 300; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 301; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:62378-5; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "62378-5" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 302; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Copy number gain | Copy number loss" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "Copy Number Change Types" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL1041-4"; fhir:link <http://loinc.org/vs/LL1041-4> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "C.1" ] ] ], [ fhir:index 303; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 304; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 305; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 306; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "arrCGH-ratio" ]; fhir:ElementDefinition.short [ fhir:value "Structural variant reported arrCGH [Ratio]" ]; fhir:ElementDefinition.definition [ fhir:value "todo." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 307; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 308; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 309; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 310; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81299-0; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81299-0" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 311; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "A fixed quantity (no comparator)" ]; fhir:ElementDefinition.definition [ fhir:value "The comparator is not used on a SimpleQuantity" ]; fhir:ElementDefinition.comment [ fhir:value "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.condition [ fhir:value "ele-1"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "qty-3" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "If a code for the unit is present, the system SHALL also be present" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "code.empty() or system.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:code)) or exists(f:system)" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Quantity"; fhir:link <http://hl7.org/fhir/StructureDefinition/Quantity> ] ], [ fhir:index 2; fhir:ElementDefinition.constraint.key [ fhir:value "sqty-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "The comparator is not used on a SimpleQuantity" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "comparator.empty()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:comparator))" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "SN (see also Range) or CQ" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "PQ, IVL<PQ>, MO, CO, depending on the values" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.29" ] ] ], [ fhir:index 312; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 313; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 314; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 315; fhir:Element.id [ fhir:value "Observation.component:complex-var-type" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "complex-var-type" ]; fhir:ElementDefinition.short [ fhir:value "Complex variant type" ]; fhir:ElementDefinition.definition [ fhir:value "The type of complex variant, for example, compound heterozygous or haplotype." ]; fhir:ElementDefinition.comment [ fhir:value "When sending a grouping of non-contiguous variants that are meant to be interpreted together but do not signify a named haplotype, one can send the type of complex variant here (determined by where the individual changes are in relation to each other), and use Observation.hasMember to reference the individual variants, which would then be described as normal." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 316; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 317; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 318; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 319; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81263-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81263-6" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 320; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Compound heterozygous | Double heterozygous | Haplotype | Hemizygous" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "Complex variant type" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL3999-1"; fhir:link <http://loinc.org/vs/LL3999-1> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "C.3" ] ] ], [ fhir:index 321; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 322; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 323; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 324; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "cytogenomic-nomenclature" ]; fhir:ElementDefinition.short [ fhir:value "Cytogenomic Nomenclature" ]; fhir:ElementDefinition.definition [ fhir:value "Fully describes a variant with a single code. Typically a large variant such as a mosaic, abnormal chromosome numbers, etc." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 325; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 326; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 327; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 328; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Variant ISCN" ]; fhir:ElementDefinition.definition [ fhir:value "ISCN is a syntax for describing cytogenetic findings, from classical karyotypes to details that can be observed with copy number methodologies. Using ISCN nomenclature is highly recommended for reporting structural variants." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81291-7; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81291-7" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 329; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ], [ fhir:index 4; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "A.11" ] ] ], [ fhir:index 330; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 331; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 332; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ], [ fhir:index 333; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "variant-inheritance" ]; fhir:ElementDefinition.short [ fhir:value "Variant Inheritance" ]; fhir:ElementDefinition.definition [ fhir:value "Some observations have multiple component observations. These component observations are expressed as separate code value pairs that share the same attributes. Examples include systolic and diastolic component observations for blood pressure measurement and multiple component observations for genetics observations." ]; fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable). However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ] ] ], [ fhir:index 334; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ]; fhir:ElementDefinition.representation [ fhir:value "xmlAttr"; fhir:index 0 ]; fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ]; fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.id" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ]; fhir:Extension.valueUrl [ fhir:value "string" ] ]; fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 335; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.extension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ]; fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ] ] ], [ fhir:index 336; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.modifierExtension" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ]; fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ]; fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ]; fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ]; fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](https://hl7.org/fhir/extensibility.html#modifierExtension)." ]; fhir:ElementDefinition.alias [ fhir:value "extensions"; fhir:index 0 ], [ fhir:value "user content"; fhir:index 1 ], [ fhir:value "modifiers"; fhir:index 2 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Extension" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ], [ fhir:index 1; fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Extension"; fhir:link <http://hl7.org/fhir/StructureDefinition/Extension> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ] ], [ fhir:index 337; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ]; fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ]; fhir:ElementDefinition.comment [ fhir:value "*All* code-value and component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "variant-inheritance" ] ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationCode" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-codes"; fhir:link <http://hl7.org/fhir/ValueSet/observation-codes> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ]; fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "code" ] ] ], [ fhir:index 338; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Actual component result" ]; fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ]; fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an Apgar score) and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section](https://hl7.org/fhir/observation.html#notes) below." ]; fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Variant Inheritance (Sequence Ontology)" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-inheritance"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-inheritance> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ] ] ], [ fhir:index 339; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.dataAbsentReason" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ]; fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ]; fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations. One way is to simply include them in the value set and represent the exceptions in the value. For example, measurement values for a serology test could be \"detected\", \"not detected\", \"inconclusive\", or \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values. For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Because of these options, use-case agreements are required to interpret general observations for exceptional values." ]; fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "1" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.condition [ fhir:value "obs-6"; fhir:index 0 ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason"; fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ] ] ], [ fhir:index 340; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.interpretation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ]; fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value. For example, high, low, normal." ]; fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ), its use extends to other use cases where coded interpretations are relevant. Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ]; fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ]; fhir:ElementDefinition.alias [ fhir:value "Abnormal Flag"; fhir:index 0 ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "0" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ]; fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ] ]; fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation"; fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ]; fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ] ], [ fhir:index 2; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ] ], [ fhir:index 3; fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ]; fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ] ] ], [ fhir:index 341; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.referenceRange" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ]; fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ]; fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ]; fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.base [ fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ]; fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.base.max [ fhir:value "*" ] ]; fhir:ElementDefinition.contentReference [ fhir:value "#Observation.referenceRange" ]; fhir:ElementDefinition.constraint [ fhir:index 0; fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ]; fhir:ElementDefinition.constraint.severity [ fhir:value "error" ]; fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ]; fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ]; fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ]; fhir:ElementDefinition.constraint.source [ fhir:value "http://hl7.org/fhir/StructureDefinition/Element"; fhir:link <http://hl7.org/fhir/StructureDefinition/Element> ] ]; fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ]; fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ] ], [ fhir:index 1; fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ]; fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ] ] ] ]; fhir:StructureDefinition.differential [ fhir:StructureDefinition.differential.element [ fhir:index 0; fhir:Element.id [ fhir:value "Observation" ]; fhir:ElementDefinition.path [ fhir:value "Observation" ]; fhir:ElementDefinition.short [ fhir:value "Variant" ]; fhir:ElementDefinition.definition [ fhir:value "Details about a set of changes in the tested sample compared to a reference sequence." ]; fhir:ElementDefinition.comment [ fhir:value "This change can be simple/discrete (relatively short), structural (potentially very large), or complex (consisting of multiple independent co-occurring variations)." ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 1; fhir:Element.id [ fhir:value "Observation.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.code" ]; fhir:ElementDefinition.short [ fhir:value "Genetic variant assessment" ]; fhir:ElementDefinition.definition [ fhir:value "Where testing scenarios are intended to assess the prescence or absence of a known set of DNA variants (e.g. tumor profiling using genotyping technology), then the Genetic Variant Assessment is used in conjunction with answer list supports structured communication of these findings. Of note, 'No Call' is different from 'Absent', because 'No Call' did not result in the determination of the marker's presents or absents. This may be due to test failure or specimen specific context which renders the test ineffective." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69548-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69548-6" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 2; fhir:Element.id [ fhir:value "Observation.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Present|Absent|No call|Indeterminate" ]; fhir:ElementDefinition.definition [ fhir:value "Indicates whether the indicated variation was found or not." ]; fhir:ElementDefinition.comment [ fhir:value "If not searching for specific variations and merely reporting what's found, this element should be set to \"Present\"." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "Genetic Variant Assessment" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL1971-2"; fhir:link <http://loinc.org/vs/LL1971-2> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.21" ] ] ], [ fhir:index 3; fhir:Element.id [ fhir:value "Observation.method" ]; fhir:ElementDefinition.path [ fhir:value "Observation.method" ]; fhir:ElementDefinition.short [ fhir:value "Sequencing | Oligo aCGH | SNP array | BAC aCGH |Curated|+" ]; fhir:ElementDefinition.definition [ fhir:value "Indicates the method of variant analysis." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Variant analysis method type" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL4048-6"; fhir:link <http://loinc.org/vs/LL4048-6> ] ] ], [ fhir:index 4; fhir:Element.id [ fhir:value "Observation.component" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.slicing [ fhir:ElementDefinition.slicing.discriminator [ fhir:index 0; fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "pattern" ]; fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "code" ] ]; fhir:ElementDefinition.slicing.rules [ fhir:value "open" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 5; fhir:Element.id [ fhir:value "Observation.component:dna-chg" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "dna-chg" ]; fhir:ElementDefinition.short [ fhir:value "DNA Change - Transcript (cHGVS)" ]; fhir:ElementDefinition.definition [ fhir:value "Human Genome Variation Society (HGVS) nomenclature for a single DNA marker." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 6; fhir:Element.id [ fhir:value "Observation.component:dna-chg.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48004-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48004-6" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 7; fhir:Element.id [ fhir:value "Observation.component:dna-chg.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "HGVS: Sequence Variant Nomenclature from the Human Genome Variation Society" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.5 (includes A.13 in version)" ] ] ], [ fhir:index 8; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "dna-chg-type" ]; fhir:ElementDefinition.short [ fhir:value "DNA change type" ]; fhir:ElementDefinition.definition [ fhir:value "Codified type for associated DNA Marker. DNA Marker's use the HGVS notation which implies the DNA Marker Type, but the concurrent use of this code will allow a standard and explicit type for technical and display convenience." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 9; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48019-4; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48019-4" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 10; fhir:Element.id [ fhir:value "Observation.component:dna-chg-type.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Concepts in sequence ontology under SO:0002072 (see http://www.sequenceontology.org/browser/current_release/term/SO:0002072)" ]; fhir:ElementDefinition.definition [ fhir:value "Type of DNA variation reported." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "DNA Change type values (Sequence Ontology)" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.7" ] ] ], [ fhir:index 11; fhir:Element.id [ fhir:value "Observation.component:functional-annotation" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "functional-annotation" ]; fhir:ElementDefinition.short [ fhir:value "Functional Annotation" ]; fhir:ElementDefinition.definition [ fhir:value "Annotated changes to sequence features caused by this variant." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 12; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "functional-annotation" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 13; fhir:Element.id [ fhir:value "Observation.component:functional-annotation.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Concepts in sequence ontology under SO:0001537 (see http://www.sequenceontology.org/browser/current_release/term/SO:0001537)" ]; fhir:ElementDefinition.definition [ fhir:value "Changes to sequence features caused by this variant." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Functional Annotation (Sequence Ontology)" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-annotation"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-annotation> ] ] ], [ fhir:index 14; fhir:Element.id [ fhir:value "Observation.component:variation-code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "variation-code" ]; fhir:ElementDefinition.short [ fhir:value "Variation Code" ]; fhir:ElementDefinition.definition [ fhir:value "This term is used to report the unique identifier of the simple variant found in this study." ]; fhir:ElementDefinition.comment [ fhir:value "If this is present, the components can be omitted but they might be included to avoid a need to look up the information in a registry. Typically only one code would be present, though multiple codings expressing the variant in different code systems are possible." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 15; fhir:Element.id [ fhir:value "Observation.component:variation-code.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81252-9; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81252-9" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 16; fhir:Element.id [ fhir:value "Observation.component:variation-code.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.2, B.16 (A.16 in coding.version)" ] ] ], [ fhir:index 17; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "dbSNP-id" ]; fhir:ElementDefinition.short [ fhir:value "dbSNP ID" ]; fhir:ElementDefinition.definition [ fhir:value "The unique identifier for the variant represented as a small nucleotide polymorphism (SNP). The dbSNP ID is used routinely as the base identifier in pharmacogenomics as well as arrCGH studies. For example, for the simple variant NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys), the dbSNP ID is 368949613. [http://www.ncbi.nlm.nih.gov/clinvar/variation/30880/]." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 18; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81255-2; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81255-2" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 19; fhir:Element.id [ fhir:value "Observation.component:dbSNP-id.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.15 (includes A.14 in version)" ] ] ], [ fhir:index 20; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "genomic-dna-chg" ]; fhir:ElementDefinition.short [ fhir:value "DNA Change - Genomic (gHGVS)" ]; fhir:ElementDefinition.definition [ fhir:value "The name of a structural variant reported using HGVS nomenclature." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 21; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81290-9; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81290-9" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 22; fhir:Element.id [ fhir:value "Observation.component:genomic-dna-chg.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "HGVS: Sequence Variant Nomenclature from the Human Genome Variation Society" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.10 (includes A.13 in version)" ] ] ], [ fhir:index 23; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "genomic-source-class" ]; fhir:ElementDefinition.short [ fhir:value "Genomic source class" ]; fhir:ElementDefinition.definition [ fhir:value "The genomic class of the specimen being analyzed: Germline for inherited genome, somatic for cancer genome, and prenatal for fetal genome." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 24; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48002-0; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48002-0" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 25; fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Germline | Somatic | Fetal | Likely germline | Likely somatic |Likely fetal | Unknown genomic origin | De novo" ]; fhir:ElementDefinition.definition [ fhir:value "MG_2_Genetic variant source." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Genomic source class values" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL378-1"; fhir:link <http://loinc.org/vs/LL378-1> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.18" ] ] ], [ fhir:index 26; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "amino-acid-chg" ]; fhir:ElementDefinition.short [ fhir:value "Amino acid change (pHGVS)" ]; fhir:ElementDefinition.definition [ fhir:value "Human Genome Variation Society (HGVS) nomenclature for an amino acid sequence. This value is derivable from the DNA Marker value if available. It is provided for convenience. The use of the nomenclature must be extended to describe non-variations (aka. wild types) see samples for wild type examples." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 27; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48005-3; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48005-3" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 28; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "HGVS: Sequence Variant Nomenclature from the Human Genome Variation Society" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.6 (includes A.13 in version)" ] ] ], [ fhir:index 29; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "amino-acid-chg-type" ]; fhir:ElementDefinition.short [ fhir:value "Amino acid change type" ]; fhir:ElementDefinition.definition [ fhir:value "Codified type for associated Amino Acid Marker. Amino Acid Marker's use the HGVS notation which implies the Amino Acid Marker Type, but the concurrent use of this code will allow a standard and explicit type for technical and display convenience." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 30; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48006-1; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48006-1" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 31; fhir:Element.id [ fhir:value "Observation.component:amino-acid-chg-type.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Wild type | Deletion | Duplication | Frameshift | Initiating Methionine | Insertion | Insertion and Deletion | Missense | Silent | Stop Codon Mutation" ]; fhir:ElementDefinition.definition [ fhir:value "MG_4_Amino acid change type." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "Amino acid change type values" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL380-7"; fhir:link <http://loinc.org/vs/LL380-7> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.8" ] ] ], [ fhir:index 32; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "transcript-ref-seq" ]; fhir:ElementDefinition.short [ fhir:value "Transcript reference sequence ID" ]; fhir:ElementDefinition.definition [ fhir:value "This field carries the ID for the transcribed reference sequence, which is the part of the genomic reference sequence that is converted to messenger RNA (i.e., after the introns are removed)." ]; fhir:ElementDefinition.comment [ fhir:value "Only needed if the transcript sequence or genomic reference sequence versions don't indicate the version." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 33; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:51958-7; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "51958-7" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 34; fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.4" ] ] ], [ fhir:index 35; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "genomic-ref-seq" ]; fhir:ElementDefinition.short [ fhir:value "Genomic reference sequence ID" ]; fhir:ElementDefinition.definition [ fhir:value "This field carries the ID for the genomic reference sequence. The genomic reference sequence is a contiguous stretch of chromosome DNA that spans all of the exons of the gene and includes transcribed and non transcribed stretches. For this ID use either the NCBI genomic nucleotide RefSeq IDs with their version number (see: NCBI.NLM.NIH.Gov/RefSeq) or use the LRG identifiers, without transcript (t or p) extensions -- when they become available. (See- Report sponsored by GEN2PHEN at the European Bioinformatics Institute at Hinxton UK April 24-25, 2008).\rThe NCI RefSeq genomic IDs are distinguished by a prefix of\"NG\" for genes from the nuclear chromosomes and prefix of \"NC\" for genes from mitochondria. The LRG Identifiers have a prefix of \"LRG_\" Mitochondrial genes are not in the scope of LRG." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 36; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48013-7; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48013-7" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 37; fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.9" ] ] ], [ fhir:index 38; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "sample-allelic-frequency" ]; fhir:ElementDefinition.short [ fhir:value "Sample Allelic Frequency" ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 39; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Sample Sample VAF" ]; fhir:ElementDefinition.definition [ fhir:value "The fraction of all reads in a study sample at a given genomic locus that identify the allele (variant) in question." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81258-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81258-6" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 40; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.22, C.4" ] ] ], [ fhir:index 41; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].value" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].value" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 42; fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].system" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].system" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "uri" ] ]; fhir:ElementDefinition.fixedUri [ fhir:value "http://unitsofmeasure.org" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 43; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "allelic-read-depth" ]; fhir:ElementDefinition.short [ fhir:value "Allelic read depth" ]; fhir:ElementDefinition.definition [ fhir:value "Specifies the number of reads that identified the allele in question whether it consists of one or a small sequence of contiguous nucleotides. Different methods and purposes require different numbers of reads to be acceptable. Often >400, sometimes as few as 2-4." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "*" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 44; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:82121-5; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "82121-5" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 45; fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.27, C.7" ] ] ], [ fhir:index 46; fhir:Element.id [ fhir:value "Observation.component:allelic-state" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "allelic-state" ]; fhir:ElementDefinition.short [ fhir:value "Allelic state" ]; fhir:ElementDefinition.definition [ fhir:value "The level of occurrence of a single DNA Marker within a set of chromosomes. Heterozygous indicates the DNA Marker is only present in one of the two genes contained in homologous chromosomes. Homozygous indicates the DNA Marker is present in both genes contained in homologous chromosomes. Hemizygous indicates the DNA Marker exists in the only single copy of a gene in a non-homologous chromosome (The male X and Y chromosome are non-homologous). Hemiplasmic indicates that the DNA Marker is present in some but not all of the copies of mitochondrial DNA. Homoplasmic indicates that the DNA Maker is present in all of the copies of mitochondrial DNA." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 47; fhir:Element.id [ fhir:value "Observation.component:allelic-state.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:53034-5; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "53034-5" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 48; fhir:Element.id [ fhir:value "Observation.component:allelic-state.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Heteroplasmic | Homoplasmic | Homozygous | Heterozygous | Hemizygous" ]; fhir:ElementDefinition.definition [ fhir:value "The relationship between the alleles found at the same locus on different chromosomes." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Allelic state type values" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL381-5"; fhir:link <http://loinc.org/vs/LL381-5> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.23, C.6" ] ] ], [ fhir:index 49; fhir:Element.id [ fhir:value "Observation.component:copy-number" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "copy-number" ]; fhir:ElementDefinition.short [ fhir:value "Genomic structural variant copy number" ]; fhir:ElementDefinition.definition [ fhir:value "The copy number of the large variant. In HGVS, this is the numeric value following the “X”. It is a unit-less value. Note that a copy number of 1 implies a deletion. The copy number can usually be inferred from the HGVS or ISCN fields." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 50; fhir:Element.id [ fhir:value "Observation.component:copy-number.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:82155-3; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "82155-3" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 51; fhir:Element.id [ fhir:value "Observation.component:copy-number.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Count"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Count> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.28" ] ] ], [ fhir:index 52; fhir:Element.id [ fhir:value "Observation.component:ref-allele" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "ref-allele" ]; fhir:ElementDefinition.short [ fhir:value "Genomic ref allele" ]; fhir:ElementDefinition.definition [ fhir:value "Reference values (\"normal\") examined within the Reference Sequence." ]; fhir:ElementDefinition.comment [ fhir:value "This is used in a genotyping test to define the reference and variable nucleotide strings. That is if the sequence variation is an insertion, then Reference Nucleotide will be blank and Variable Nucleotide will contain the inserted nucleotides. In contrast, if the sequence variation is a deletion, then the Reference Nucleotide will contain the deleted nucliotieds, and the Variable Nucleotide will be blank." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.9" ] ] ], [ fhir:index 53; fhir:Element.id [ fhir:value "Observation.component:ref-allele.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69547-8; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69547-8" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 54; fhir:Element.id [ fhir:value "Observation.component:ref-allele.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "string" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 55; fhir:Element.id [ fhir:value "Observation.component:alt-allele" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "alt-allele" ]; fhir:ElementDefinition.short [ fhir:value "Genomic alt allele" ]; fhir:ElementDefinition.definition [ fhir:value "The genomic alternate allele is the contiguous segment of DNA in the test sample that differs from the reference allele at the same location and thus defines a variant." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.11" ] ] ], [ fhir:index 56; fhir:Element.id [ fhir:value "Observation.component:alt-allele.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69551-0; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69551-0" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 57; fhir:Element.id [ fhir:value "Observation.component:alt-allele.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "string" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 58; fhir:Element.id [ fhir:value "Observation.component:coordinate-system" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "coordinate-system" ]; fhir:ElementDefinition.short [ fhir:value "Coordinate System" ]; fhir:ElementDefinition.definition [ fhir:value "Base number of coordinate system either 0-based, with inclusive start and exclusive end (called interval), or 1-based, with inclusive start and end. However, two versions of 1-based are in common use.These systems are HGVS 1-based (called variant method) and VCF 1-based (called alignment method). In general, HGVS recommends right-justification and VCF recommends left-justification. However, these systems further address questions such as wheather or not to place an insertion before or after the nucleotide, and, if always placed before the nucleotide, how to handle insertion after the end of the sequence. Additionally, the systems deal with handling boundary effects of numbers between features. For more details see the HGVS and VCF guides." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 59; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.definition [ fhir:value "This captures the base numbering used to calculate base positions in the reported sequence information." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:92822-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "92822-6" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 60; fhir:Element.id [ fhir:value "Observation.component:coordinate-system.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "0-based interval | 0-based character | 1-based character" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ]; fhir:ElementDefinition.binding.description [ fhir:value "Base coordinate systems start and end measurements for variants" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL5323-2"; fhir:link <http://loinc.org/vs/LL5323-2> ] ] ], [ fhir:index 61; fhir:Element.id [ fhir:value "Observation.component:exact-start-end" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "exact-start-end" ]; fhir:ElementDefinition.short [ fhir:value "Exact start-end" ]; fhir:ElementDefinition.definition [ fhir:value "This location is the first genomic position in the reference allele that contains a change from the reference allele. For example, for the simple variant NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys), the location is Chr3: 128906220 on Assembly GRCh38." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.10" ] ] ], [ fhir:index 62; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "exact-start-end" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 63; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Range" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 64; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x].low" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].low" ]; fhir:ElementDefinition.short [ fhir:value "Exact Start" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 65; fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x].high" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].high" ]; fhir:ElementDefinition.short [ fhir:value "Exact End" ]; fhir:ElementDefinition.definition [ fhir:value "Optional since many representations (VCF, SPDI) only provide a single position." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 66; fhir:Element.id [ fhir:value "Observation.component:variant-length" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "variant-length" ]; fhir:ElementDefinition.short [ fhir:value "Structural variant length" ]; fhir:ElementDefinition.definition [ fhir:value "Length of the structural variant, which information may be ascertained in some but not all types of structural variants." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 67; fhir:Element.id [ fhir:value "Observation.component:variant-length.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81300-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81300-6" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 68; fhir:Element.id [ fhir:value "Observation.component:variant-length.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/Count"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/Count> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.30" ] ] ], [ fhir:index 69; fhir:Element.id [ fhir:value "Observation.component:outer-start-end" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "outer-start-end" ]; fhir:ElementDefinition.short [ fhir:value "Variant outer start and end" ]; fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the widest genomic range in which the variant might reside." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 70; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "outer-start-end" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 71; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Range" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.31" ] ] ], [ fhir:index 72; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x].low" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].low" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 73; fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x].high" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].high" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 74; fhir:Element.id [ fhir:value "Observation.component:inner-start-end" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "inner-start-end" ]; fhir:ElementDefinition.short [ fhir:value "Variant inner start and end" ]; fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the narrowest genomic range in which the structural variant might reside." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 75; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "inner-start-end" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 76; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Range" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.32" ] ] ], [ fhir:index 77; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x].low" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].low" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 78; fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x].high" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].high" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 79; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "chromosome-copy-number-change-type" ]; fhir:ElementDefinition.short [ fhir:value "Chromosome copy number change type" ]; fhir:ElementDefinition.definition [ fhir:value "The type of the chromosome copy number change." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 80; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:62378-5; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "62378-5" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 81; fhir:Element.id [ fhir:value "Observation.component:chromosome-copy-number-change-type.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Copy number gain | Copy number loss" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "Copy Number Change Types" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL1041-4"; fhir:link <http://loinc.org/vs/LL1041-4> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "C.1" ] ] ], [ fhir:index 82; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "arrCGH-ratio" ]; fhir:ElementDefinition.short [ fhir:value "Structural variant reported arrCGH [Ratio]" ]; fhir:ElementDefinition.definition [ fhir:value "todo." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 83; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81299-0; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81299-0" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 84; fhir:Element.id [ fhir:value "Observation.component:arrCGH-ratio.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]; fhir:ElementDefinition.type.profile [ fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"; fhir:index 0; fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity> ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "B.29" ] ] ], [ fhir:index 85; fhir:Element.id [ fhir:value "Observation.component:complex-var-type" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "complex-var-type" ]; fhir:ElementDefinition.short [ fhir:value "Complex variant type" ]; fhir:ElementDefinition.definition [ fhir:value "The type of complex variant, for example, compound heterozygous or haplotype." ]; fhir:ElementDefinition.comment [ fhir:value "When sending a grouping of non-contiguous variants that are meant to be interpreted together but do not signify a named haplotype, one can send the type of complex variant here (determined by where the individual changes are in relation to each other), and use Observation.hasMember to reference the individual variants, which would then be described as normal." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 86; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81263-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81263-6" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 87; fhir:Element.id [ fhir:value "Observation.component:complex-var-type.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.short [ fhir:value "Compound heterozygous | Double heterozygous | Haplotype | Hemizygous" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "required" ]; fhir:ElementDefinition.binding.description [ fhir:value "Complex variant type" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://loinc.org/vs/LL3999-1"; fhir:link <http://loinc.org/vs/LL3999-1> ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "C.3" ] ] ], [ fhir:index 88; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "cytogenomic-nomenclature" ]; fhir:ElementDefinition.short [ fhir:value "Cytogenomic Nomenclature" ]; fhir:ElementDefinition.definition [ fhir:value "Fully describes a variant with a single code. Typically a large variant such as a mosaic, abnormal chromosome numbers, etc." ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 89; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.short [ fhir:value "Variant ISCN" ]; fhir:ElementDefinition.definition [ fhir:value "ISCN is a syntax for describing cytogenetic findings, from classical karyotypes to details that can be observed with copy number methodologies. Using ISCN nomenclature is highly recommended for reporting structural variants." ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81291-7; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81291-7" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 90; fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "example" ]; fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ] ]; fhir:ElementDefinition.mapping [ fhir:index 0; fhir:ElementDefinition.mapping.identity [ fhir:value "v2-cg-results" ]; fhir:ElementDefinition.mapping.map [ fhir:value "A.11" ] ] ], [ fhir:index 91; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component" ]; fhir:ElementDefinition.sliceName [ fhir:value "variant-inheritance" ]; fhir:ElementDefinition.short [ fhir:value "Variant Inheritance" ]; fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 92; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.code" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.patternCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "variant-inheritance" ] ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ] ], [ fhir:index 93; fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.value[x]" ]; fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ]; fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ]; fhir:ElementDefinition.max [ fhir:value "1" ]; fhir:ElementDefinition.type [ fhir:index 0; fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ] ]; fhir:ElementDefinition.mustSupport [ fhir:value "false"^^xsd:boolean ]; fhir:ElementDefinition.binding [ fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ]; fhir:ElementDefinition.binding.description [ fhir:value "Variant Inheritance (Sequence Ontology)" ]; fhir:ElementDefinition.binding.valueSet [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-inheritance"; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-inheritance> ] ] ] ]. # - ontology header ------------------------------------------------------------ a owl:Ontology; owl:imports fhir:fhir.ttl.
IG © 2017+ HL7 International Clinical Genomics Work Group. Package hl7.fhir.uv.genomics-reporting#1.0.0 based on FHIR 4.0.1. Generated 2019-11-20
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