Genomics Reporting Implementation Guide (STU1)
This page is part of the Genetic Reporting Implementation Guide (v1.0.0: STU 1) based on FHIR R4. The current version which supercedes this version is 2.0.0. For a full list of available versions, see the Directory of published versions 
@prefix fhir: <http://hl7.org/fhir/> . @prefix loinc: <http://loinc.org/rdf#> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- a fhir:Bundle; fhir:nodeRole fhir:treeRoot; fhir:Resource.id [ fhir:value "diagnosticreport-pgxexample"]; fhir:Bundle.type [ fhir:value "transaction"]; fhir:Bundle.entry [ fhir:index 0; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/DiagnosticReport/pgx-report" ]; fhir:Bundle.entry.resource <http://example.org/fhir/DiagnosticReport/pgx-report>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "DiagnosticReport" ] ] ], [ fhir:index 1; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Patient/patient" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Patient/patient>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Patient" ] ] ], [ fhir:index 2; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Specimen/specimen" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Specimen/specimen>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Patient" ] ] ], [ fhir:index 3; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Organization/lab" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Organization/lab>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Organization" ] ] ], [ fhir:index 4; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/ServiceRequest/pgx-request" ]; fhir:Bundle.entry.resource <http://example.org/fhir/ServiceRequest/pgx-request>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "ServiceRequest" ] ] ], [ fhir:index 5; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Observation/med-impact-pgx-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Observation/med-impact-pgx-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Observation" ] ] ], [ fhir:index 6; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Observation/genotype-pgx-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Observation/genotype-pgx-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Observation" ] ] ], [ fhir:index 7; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Observation/haplotype-1-pgx-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Observation/haplotype-1-pgx-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Observation" ] ] ], [ fhir:index 8; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Observation/haplotype-2-pgx-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Observation/haplotype-2-pgx-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Observation" ] ] ], [ fhir:index 9; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Observation/variant-1-pgx-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Observation/variant-1-pgx-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Observation" ] ] ], [ fhir:index 10; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Observation/variant-2-pgx-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Observation/variant-2-pgx-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Observation" ] ] ], [ fhir:index 11; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/MolecularSequence/sequence-1-pgx-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/MolecularSequence/sequence-1-pgx-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "MolecularSequence" ] ] ], [ fhir:index 12; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/MolecularSequence/sequence-2-pgx-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/MolecularSequence/sequence-2-pgx-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "MolecularSequence" ] ] ], [ fhir:index 13; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/Task/med-usage-impact-task-pgx-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/Task/med-usage-impact-task-pgx-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "Task" ] ] ], [ fhir:index 14; fhir:Bundle.entry.fullUrl [ fhir:value "http://example.org/fhir/MedicationStatement/current-med-example" ]; fhir:Bundle.entry.resource <http://example.org/fhir/MedicationStatement/current-med-example>; fhir:Bundle.entry.request [ fhir:Bundle.entry.request.method [ fhir:value "POST" ]; fhir:Bundle.entry.request.url [ fhir:value "MedicationStatement" ] ] ]. <http://example.org/fhir/DiagnosticReport/pgx-report> a fhir:DiagnosticReport; fhir:Resource.id [ fhir:value "pgx-report"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomics-report"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomics-report> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: pgx-report</p><p><b>meta</b>: </p><p><b>basedOn</b>: <a href=\"ServiceRequest/pgx-request\">ServiceRequest/pgx-request</a></p><p><b>status</b>: final</p><p><b>code</b>: Master HL7 genetic variant reporting panel <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '81247-9' = 'Master HL7 genetic variant reporting panel)</span></p><p><b>subject</b>: <a href=\"Patient/patient\">Patient/patient</a></p><p><b>effective</b>: Jan 1, 2016 12:00:00 AM</p><p><b>issued</b>: Mar 6, 2018 12:00:00 AM</p><p><b>performer</b>: <a href=\"Organization/lab\">Organization/lab</a></p><p><b>result</b>: </p><ul><li><a href=\"Observation/med-impact-pgx-example\">genetics impact for medication metabolism accessment</a></li><li><a href=\"Observation/genotype-pgx-example\">Observation/genotype-pgx-example</a></li><li><a href=\"Observation/haplotype-1-pgx-example\">Observation/haplotype-1-pgx-example</a></li><li><a href=\"Observation/haplotype-2-pgx-example\">Observation/haplotype-2-pgx-example</a></li><li><a href=\"Observation/variant-1-pgx-example\">Observation/variant-1-pgx-example</a></li><li><a href=\"Observation/variant-2-pgx-example\">Observation/variant-2-pgx-example</a></li></ul></div>" ]; fhir:DomainResource.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/RecommendedAction" ]; fhir:Extension.valueReference [ fhir:Reference.reference [ fhir:value "Task/med-usage-impact-task-pgx-example" ] ] ]; fhir:DiagnosticReport.basedOn [ fhir:index 0; fhir:Reference.reference [ fhir:value "ServiceRequest/pgx-request" ] ]; fhir:DiagnosticReport.status [ fhir:value "final"]; fhir:DiagnosticReport.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81247-9; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81247-9" ] ] ]; fhir:DiagnosticReport.subject [ fhir:Reference.reference [ fhir:value "Patient/patient" ] ]; fhir:DiagnosticReport.effectiveDateTime [ fhir:value "2016"^^xsd:gYear]; fhir:DiagnosticReport.issued [ fhir:value "2018-03-06T00:00:00-05:00"^^xsd:dateTime]; fhir:DiagnosticReport.performer [ fhir:index 0; fhir:Reference.reference [ fhir:value "Organization/lab" ] ]; fhir:DiagnosticReport.result [ fhir:index 0; fhir:Reference.reference [ fhir:value "Observation/med-impact-pgx-example" ]; fhir:Reference.display [ fhir:value "genetics impact for medication metabolism accessment" ] ], [ fhir:index 1; fhir:Reference.reference [ fhir:value "Observation/genotype-pgx-example" ] ], [ fhir:index 2; fhir:Reference.reference [ fhir:value "Observation/haplotype-1-pgx-example" ] ], [ fhir:index 3; fhir:Reference.reference [ fhir:value "Observation/haplotype-2-pgx-example" ] ], [ fhir:index 4; fhir:Reference.reference [ fhir:value "Observation/variant-1-pgx-example" ] ], [ fhir:index 5; fhir:Reference.reference [ fhir:value "Observation/variant-2-pgx-example" ] ]. <http://example.org/fhir/Patient/patient> a fhir:Patient; fhir:Resource.id [ fhir:value "patient"]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "additional" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">This would contain patient identifiers, demographics, etc.</div>" ]. <http://example.org/fhir/Specimen/specimen> a fhir:Specimen; fhir:Resource.id [ fhir:value "specimen"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/specimen"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/specimen> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">TODO</div>" ]; fhir:Specimen.subject [ fhir:Reference.reference [ fhir:value "Patient/patient" ] ]. <http://example.org/fhir/Organization/lab> a fhir:Organization; fhir:Resource.id [ fhir:value "lab"]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">TODO</div>" ]; fhir:Organization.name [ fhir:value "Some lab"]. <http://example.org/fhir/ServiceRequest/pgx-request> a fhir:ServiceRequest; fhir:Resource.id [ fhir:value "pgx-request"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/servicerequest"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/servicerequest> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">TODO</div>" ]; fhir:ServiceRequest.status [ fhir:value "active"]; fhir:ServiceRequest.intent [ fhir:value "original-order"]; fhir:ServiceRequest.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81247-9; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81247-9" ] ] ]; fhir:ServiceRequest.subject [ fhir:Reference.reference [ fhir:value "Patient/patient" ] ]; fhir:ServiceRequest.reasonCode [ fhir:index 0; fhir:CodeableConcept.text [ fhir:value "Worried about family planning" ] ]. <http://example.org/fhir/Observation/med-impact-pgx-example> a fhir:Observation; fhir:Resource.id [ fhir:value "med-impact-pgx-example"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/medication-metabolism"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/medication-metabolism> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: med-impact-pgx-example</p><p><b>meta</b>: </p><p><b>status</b>: final</p><p><b>category</b>: Laboratory <span style=\"background: LightGoldenRodYellow\">(Details : {http://terminology.hl7.org/CodeSystem/observation-category code 'laboratory' = 'Laboratory)</span></p><p><b>code</b>: Genetic variation's effect on drug metabolism <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '53040-2' = 'Genetic variation's effect on drug metabolism', given as 'Genetic variation's effect on drug metabolism'})</span></p><p><b>subject</b>: <a href=\"Patient/patient\">Patient/patient</a></p><p><b>effective</b>: Jan 1, 2018 12:00:00 AM</p><p><b>issued</b>: Mar 6, 2018 12:00:00 AM</p><p><b>performer</b>: <a href=\"Organization/lab\">Organization/lab</a></p><p><b>value</b>: Rapid metabolizer <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code 'LA25390-8' = 'Rapid metabolizer', given as 'Rapid metabolizer'})</span></p><p><b>derivedFrom</b>: <a href=\"Observation/genotype-pgx-example\">Observation/genotype-pgx-example</a></p><h3>Components</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td>*</td><td>Medication assessed <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '51963-7' = 'Medication assessed [ID]', given as 'Medication assessed'})</span></td><td>mercaptopurine <span style=\"background: LightGoldenRodYellow\">(Details : {RxNorm code '103' = 'mercaptopurine', given as 'mercaptopurine'})</span></td></tr></table></div>" ]; fhir:Observation.status [ fhir:value "final"]; fhir:Observation.category [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ]; fhir:Coding.code [ fhir:value "laboratory" ] ] ]; fhir:Observation.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:53040-2; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "53040-2" ]; fhir:Coding.display [ fhir:value "Genetic variation's effect on drug metabolism" ] ] ]; fhir:Observation.subject [ fhir:Reference.reference [ fhir:value "Patient/patient" ] ]; fhir:Observation.effectiveDateTime [ fhir:value "2018"^^xsd:gYear]; fhir:Observation.issued [ fhir:value "2018-03-06T00:00:00-05:00"^^xsd:dateTime]; fhir:Observation.performer [ fhir:index 0; fhir:Reference.reference [ fhir:value "Organization/lab" ] ]; fhir:Observation.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:LA25390-8; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "LA25390-8" ]; fhir:Coding.display [ fhir:value "Rapid metabolizer" ] ] ]; fhir:Observation.derivedFrom [ fhir:index 0; fhir:Reference.reference [ fhir:value "Observation/genotype-pgx-example" ] ]; fhir:Observation.component [ fhir:index 0; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:51963-7; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "51963-7" ]; fhir:Coding.display [ fhir:value "Medication assessed" ] ] ]; fhir:Observation.component.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ]; fhir:Coding.code [ fhir:value "103" ]; fhir:Coding.display [ fhir:value "mercaptopurine" ] ] ] ]. <http://example.org/fhir/Observation/genotype-pgx-example> a fhir:Observation; fhir:Resource.id [ fhir:value "genotype-pgx-example"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genotype"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genotype> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: genotype-pgx-example</p><p><b>meta</b>: </p><p><b>status</b>: final</p><p><b>category</b>: Laboratory <span style=\"background: LightGoldenRodYellow\">(Details : {http://terminology.hl7.org/CodeSystem/observation-category code 'laboratory' = 'Laboratory)</span></p><p><b>code</b>: genotype display name <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '84413-4' = 'Genotype display name', given as 'genotype display name'})</span></p><p><b>effective</b>: Jan 1, 2018 12:00:00 AM</p><p><b>issued</b>: Mar 6, 2018 12:00:00 AM</p><p><b>value</b>: CYP2C9 *4/*35B <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.pharmvar.org code 'CYP2C9 *4/*35B' = 'CYP2C9 *4/*35B', given as 'CYP2C9 *4/*35B'})</span></p><p><b>specimen</b>: <a href=\"Specimen/specimen\">Specimen/specimen</a></p><p><b>derivedFrom</b>: </p><ul><li><a href=\"Observation/haplotype-1-pgx-example\">Observation/haplotype-1-pgx-example</a></li><li><a href=\"Observation/haplotype-2-pgx-example\">Observation/haplotype-2-pgx-example</a></li></ul><h3>Components</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td>*</td><td>Gene studied ID <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '48018-6' = 'Gene studied [ID]', given as 'Gene studied ID'})</span></td><td>CYP2C9 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.genenames.org/geneId code '2623' = '2623', given as 'CYP2C9'})</span></td></tr></table></div>" ]; fhir:Observation.status [ fhir:value "final"]; fhir:Observation.category [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ]; fhir:Coding.code [ fhir:value "laboratory" ] ] ]; fhir:Observation.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:84413-4; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "84413-4" ]; fhir:Coding.display [ fhir:value "genotype display name" ] ] ]; fhir:Observation.effectiveDateTime [ fhir:value "2018"^^xsd:gYear]; fhir:Observation.issued [ fhir:value "2018-03-06T00:00:00-05:00"^^xsd:dateTime]; fhir:Observation.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.pharmvar.org" ]; fhir:Coding.code [ fhir:value "CYP2C9 *4/*35B" ]; fhir:Coding.display [ fhir:value "CYP2C9 *4/*35B" ] ] ]; fhir:Observation.specimen [ fhir:Reference.reference [ fhir:value "Specimen/specimen" ] ]; fhir:Observation.derivedFrom [ fhir:index 0; fhir:Reference.reference [ fhir:value "Observation/haplotype-1-pgx-example" ] ], [ fhir:index 1; fhir:Reference.reference [ fhir:value "Observation/haplotype-2-pgx-example" ] ]; fhir:Observation.component [ fhir:index 0; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48018-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48018-6" ]; fhir:Coding.display [ fhir:value "Gene studied ID" ] ] ]; fhir:Observation.component.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.genenames.org/geneId" ]; fhir:Coding.code [ fhir:value "2623" ]; fhir:Coding.display [ fhir:value "CYP2C9" ] ] ] ]. <http://example.org/fhir/Observation/haplotype-1-pgx-example> a fhir:Observation; fhir:Resource.id [ fhir:value "haplotype-1-pgx-example"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/haplotype"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/haplotype> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: haplotype-1-pgx-example</p><p><b>meta</b>: </p><p><b>status</b>: final</p><p><b>category</b>: Laboratory <span style=\"background: LightGoldenRodYellow\">(Details : {http://terminology.hl7.org/CodeSystem/observation-category code 'laboratory' = 'Laboratory)</span></p><p><b>code</b>: Haplotype Name <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '84414-2' = 'Haplotype name', given as 'Haplotype Name'})</span></p><p><b>effective</b>: Jan 1, 2018 12:00:00 AM</p><p><b>issued</b>: Mar 6, 2018 12:00:00 AM</p><p><b>value</b>: CYP2C9 *35B <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.pharmvar.org code 'CYP2C9 *35B' = 'CYP2C9 *35B', given as 'CYP2C9 *35B'})</span></p><p><b>specimen</b>: <a href=\"Specimen/specimen\">Specimen/specimen</a></p><p><b>derivedFrom</b>: <a href=\"Observation/variant-1-pgx-example\">Observation/variant-1-pgx-example</a></p><h3>Components</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td>*</td><td>Gene studied ID <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '48018-6' = 'Gene studied [ID]', given as 'Gene studied ID'})</span></td><td>CYP2C9 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.genenames.org/geneId code '2623' = '2623', given as 'CYP2C9'})</span></td></tr></table></div>" ]; fhir:Observation.status [ fhir:value "final"]; fhir:Observation.category [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ]; fhir:Coding.code [ fhir:value "laboratory" ] ] ]; fhir:Observation.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:84414-2; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "84414-2" ]; fhir:Coding.display [ fhir:value "Haplotype Name" ] ] ]; fhir:Observation.effectiveDateTime [ fhir:value "2018"^^xsd:gYear]; fhir:Observation.issued [ fhir:value "2018-03-06T00:00:00-05:00"^^xsd:dateTime]; fhir:Observation.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.pharmvar.org" ]; fhir:Coding.code [ fhir:value "CYP2C9 *35B" ]; fhir:Coding.display [ fhir:value "CYP2C9 *35B" ] ] ]; fhir:Observation.specimen [ fhir:Reference.reference [ fhir:value "Specimen/specimen" ] ]; fhir:Observation.derivedFrom [ fhir:index 0; fhir:Reference.reference [ fhir:value "Observation/variant-1-pgx-example" ] ]; fhir:Observation.component [ fhir:index 0; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48018-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48018-6" ]; fhir:Coding.display [ fhir:value "Gene studied ID" ] ] ]; fhir:Observation.component.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.genenames.org/geneId" ]; fhir:Coding.code [ fhir:value "2623" ]; fhir:Coding.display [ fhir:value "CYP2C9" ] ] ] ]. <http://example.org/fhir/Observation/haplotype-2-pgx-example> a fhir:Observation; fhir:Resource.id [ fhir:value "haplotype-2-pgx-example"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/haplotype"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/haplotype> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: haplotype-2-pgx-example</p><p><b>meta</b>: </p><p><b>status</b>: final</p><p><b>category</b>: Laboratory <span style=\"background: LightGoldenRodYellow\">(Details : {http://terminology.hl7.org/CodeSystem/observation-category code 'laboratory' = 'Laboratory)</span></p><p><b>code</b>: Haplotype Name <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '84414-2' = 'Haplotype name', given as 'Haplotype Name'})</span></p><p><b>effective</b>: Jan 1, 2018 12:00:00 AM</p><p><b>issued</b>: Mar 6, 2018 12:00:00 AM</p><p><b>value</b>: CYP2C9 *4 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.pharmvar.org code 'CYP2C9 *4' = 'CYP2C9 *4', given as 'CYP2C9 *4'})</span></p><p><b>specimen</b>: <a href=\"Specimen/specimen\">Specimen/specimen</a></p><p><b>derivedFrom</b>: <a href=\"Observation/variant-2-pgx-example\">Observation/variant-2-pgx-example</a></p><h3>Components</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td>*</td><td>Gene studied ID <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '48018-6' = 'Gene studied [ID]', given as 'Gene studied ID'})</span></td><td>CYP2C9 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.genenames.org/geneId code '2623' = '2623', given as 'CYP2C9'})</span></td></tr></table></div>" ]; fhir:Observation.status [ fhir:value "final"]; fhir:Observation.category [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ]; fhir:Coding.code [ fhir:value "laboratory" ] ] ]; fhir:Observation.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:84414-2; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "84414-2" ]; fhir:Coding.display [ fhir:value "Haplotype Name" ] ] ]; fhir:Observation.effectiveDateTime [ fhir:value "2018"^^xsd:gYear]; fhir:Observation.issued [ fhir:value "2018-03-06T00:00:00-05:00"^^xsd:dateTime]; fhir:Observation.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.pharmvar.org" ]; fhir:Coding.code [ fhir:value "CYP2C9 *4" ]; fhir:Coding.display [ fhir:value "CYP2C9 *4" ] ] ]; fhir:Observation.specimen [ fhir:Reference.reference [ fhir:value "Specimen/specimen" ] ]; fhir:Observation.derivedFrom [ fhir:index 0; fhir:Reference.reference [ fhir:value "Observation/variant-2-pgx-example" ] ]; fhir:Observation.component [ fhir:index 0; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48018-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48018-6" ]; fhir:Coding.display [ fhir:value "Gene studied ID" ] ] ]; fhir:Observation.component.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.genenames.org/geneId" ]; fhir:Coding.code [ fhir:value "2623" ]; fhir:Coding.display [ fhir:value "CYP2C9" ] ] ] ]. <http://example.org/fhir/Observation/variant-1-pgx-example> a fhir:Observation; fhir:Resource.id [ fhir:value "variant-1-pgx-example"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: variant-1-pgx-example</p><p><b>meta</b>: </p><p><b>status</b>: final</p><p><b>category</b>: Laboratory <span style=\"background: LightGoldenRodYellow\">(Details : {http://terminology.hl7.org/CodeSystem/observation-category code 'laboratory' = 'Laboratory)</span></p><p><b>code</b>: Genetic variant assessment <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '69548-6' = 'Genetic variant assessment', given as 'Genetic variant assessment'})</span></p><p><b>effective</b>: Jan 1, 2018 12:00:00 AM</p><p><b>issued</b>: Mar 6, 2018 12:00:00 AM</p><p><b>value</b>: Present <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code 'LA9633-4' = 'Present', given as 'Present'})</span></p><p><b>specimen</b>: <a href=\"Specimen/specimen\">Specimen/specimen</a></p><p><b>derivedFrom</b>: <a href=\"MolecularSequence/sequence-1-pgx-example\">MolecularSequence/sequence-1-pgx-example</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Gene studied ID <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '48018-6' = 'Gene studied [ID]', given as 'Gene studied ID'})</span></p><p><b>value</b>: CYP2C9 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.genenames.org/geneId code '2623' = '2623', given as 'CYP2C9'})</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: dbSNP ID <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '81255-2' = 'dbSNP [ID]', given as 'dbSNP ID'})</span></p><p><b>value</b>: rs12345 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.ncbi.nlm.nih.gov/SNP code 'rs12345' = 'rs12345)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Ref nucleotide <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '69547-8' = 'Genomic ref allele [ID]', given as 'Ref nucleotide'})</span></p><p><b>value</b>: T</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alt allele <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '69551-0' = 'Genomic alt allele [ID]', given as 'Alt allele'})</span></p><p><b>value</b>: G</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Variant exact start and end <span style=\"background: LightGoldenRodYellow\">(Details : {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes code 'exact-start-end' = 'Variant exact start and end', given as 'Variant exact start and end'})</span></p><p><b>value</b>: 55227976-55227977</p></blockquote></div>" ]; fhir:Observation.status [ fhir:value "final"]; fhir:Observation.category [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ]; fhir:Coding.code [ fhir:value "laboratory" ] ] ]; fhir:Observation.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69548-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69548-6" ]; fhir:Coding.display [ fhir:value "Genetic variant assessment" ] ] ]; fhir:Observation.effectiveDateTime [ fhir:value "2018"^^xsd:gYear]; fhir:Observation.issued [ fhir:value "2018-03-06T00:00:00-05:00"^^xsd:dateTime]; fhir:Observation.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:LA9633-4; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "LA9633-4" ]; fhir:Coding.display [ fhir:value "Present" ] ] ]; fhir:Observation.specimen [ fhir:Reference.reference [ fhir:value "Specimen/specimen" ] ]; fhir:Observation.derivedFrom [ fhir:index 0; fhir:Reference.reference [ fhir:value "MolecularSequence/sequence-1-pgx-example" ] ]; fhir:Observation.component [ fhir:index 0; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48018-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48018-6" ]; fhir:Coding.display [ fhir:value "Gene studied ID" ] ] ]; fhir:Observation.component.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.genenames.org/geneId" ]; fhir:Coding.code [ fhir:value "2623" ]; fhir:Coding.display [ fhir:value "CYP2C9" ] ] ] ], [ fhir:index 1; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81255-2; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81255-2" ]; fhir:Coding.display [ fhir:value "dbSNP ID" ] ] ]; fhir:Observation.component.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.ncbi.nlm.nih.gov/SNP" ]; fhir:Coding.code [ fhir:value "rs12345" ] ] ] ], [ fhir:index 2; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69547-8; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69547-8" ]; fhir:Coding.display [ fhir:value "Ref nucleotide" ] ] ]; fhir:Observation.component.valueString [ fhir:value "T" ] ], [ fhir:index 3; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69551-0; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69551-0" ]; fhir:Coding.display [ fhir:value "Alt allele" ] ] ]; fhir:Observation.component.valueString [ fhir:value "G" ] ], [ fhir:index 4; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "exact-start-end" ]; fhir:Coding.display [ fhir:value "Variant exact start and end" ] ] ]; fhir:Observation.component.valueRange [ fhir:Range.low [ fhir:Quantity.value [ fhir:value "55227976"^^xsd:decimal ] ]; fhir:Range.high [ fhir:Quantity.value [ fhir:value "55227977"^^xsd:decimal ] ] ] ]. <http://example.org/fhir/Observation/variant-2-pgx-example> a fhir:Observation; fhir:Resource.id [ fhir:value "variant-2-pgx-example"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: variant-2-pgx-example</p><p><b>meta</b>: </p><p><b>status</b>: final</p><p><b>category</b>: Laboratory <span style=\"background: LightGoldenRodYellow\">(Details : {http://terminology.hl7.org/CodeSystem/observation-category code 'laboratory' = 'Laboratory)</span></p><p><b>code</b>: Genetic variant assessment <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '69548-6' = 'Genetic variant assessment', given as 'Genetic variant assessment'})</span></p><p><b>effective</b>: Jan 1, 2018 12:00:00 AM</p><p><b>issued</b>: Mar 6, 2018 12:00:00 AM</p><p><b>value</b>: Present <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code 'LA9633-4' = 'Present', given as 'Present'})</span></p><p><b>specimen</b>: <a href=\"Specimen/specimen\">Specimen/specimen</a></p><p><b>derivedFrom</b>: <a href=\"MolecularSequence/sequence-2-pgx-example\">MolecularSequence/sequence-2-pgx-example</a></p><blockquote><p><b>component</b></p><p><b>code</b>: Gene studied ID <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '48018-6' = 'Gene studied [ID]', given as 'Gene studied ID'})</span></p><p><b>value</b>: CYP2C9 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.genenames.org/geneId code '2623' = '2623', given as 'CYP2C9'})</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Genomic reference sequence ID <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '48013-7' = 'Genomic reference sequence [ID]', given as 'Genomic reference sequence ID'})</span></p><p><b>value</b>: NG_007726.3 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.ncbi.nlm.nih.gov/nuccore code 'NG_007726.3' = 'NG_007726.3)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: dbSNP ID <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '81255-2' = 'dbSNP [ID]', given as 'dbSNP ID'})</span></p><p><b>value</b>: rs233455 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.ncbi.nlm.nih.gov/SNP code 'rs233455' = 'rs233455)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Ref nucleotide <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '69547-8' = 'Genomic ref allele [ID]', given as 'Ref nucleotide'})</span></p><p><b>value</b>: T</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Alt allele <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code '69551-0' = 'Genomic alt allele [ID]', given as 'Alt allele'})</span></p><p><b>value</b>: G</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Variant exact start and end <span style=\"background: LightGoldenRodYellow\">(Details : {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes code 'exact-start-end' = 'Variant exact start and end', given as 'Variant exact start and end'})</span></p><p><b>value</b>: 55227978-55227979</p></blockquote></div>" ]; fhir:Observation.status [ fhir:value "final"]; fhir:Observation.category [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ]; fhir:Coding.code [ fhir:value "laboratory" ] ] ]; fhir:Observation.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69548-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69548-6" ]; fhir:Coding.display [ fhir:value "Genetic variant assessment" ] ] ]; fhir:Observation.effectiveDateTime [ fhir:value "2018"^^xsd:gYear]; fhir:Observation.issued [ fhir:value "2018-03-06T00:00:00-05:00"^^xsd:dateTime]; fhir:Observation.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:LA9633-4; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "LA9633-4" ]; fhir:Coding.display [ fhir:value "Present" ] ] ]; fhir:Observation.specimen [ fhir:Reference.reference [ fhir:value "Specimen/specimen" ] ]; fhir:Observation.derivedFrom [ fhir:index 0; fhir:Reference.reference [ fhir:value "MolecularSequence/sequence-2-pgx-example" ] ]; fhir:Observation.component [ fhir:index 0; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48018-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48018-6" ]; fhir:Coding.display [ fhir:value "Gene studied ID" ] ] ]; fhir:Observation.component.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.genenames.org/geneId" ]; fhir:Coding.code [ fhir:value "2623" ]; fhir:Coding.display [ fhir:value "CYP2C9" ] ] ] ], [ fhir:index 1; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:48013-7; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "48013-7" ]; fhir:Coding.display [ fhir:value "Genomic reference sequence ID" ] ] ]; fhir:Observation.component.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.ncbi.nlm.nih.gov/nuccore" ]; fhir:Coding.code [ fhir:value "NG_007726.3" ] ] ] ], [ fhir:index 2; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:81255-2; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "81255-2" ]; fhir:Coding.display [ fhir:value "dbSNP ID" ] ] ]; fhir:Observation.component.valueCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.ncbi.nlm.nih.gov/SNP" ]; fhir:Coding.code [ fhir:value "rs233455" ] ] ] ], [ fhir:index 3; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69547-8; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69547-8" ]; fhir:Coding.display [ fhir:value "Ref nucleotide" ] ] ]; fhir:Observation.component.valueString [ fhir:value "T" ] ], [ fhir:index 4; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:69551-0; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "69551-0" ]; fhir:Coding.display [ fhir:value "Alt allele" ] ] ]; fhir:Observation.component.valueString [ fhir:value "G" ] ], [ fhir:index 5; fhir:Observation.component.code [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes" ]; fhir:Coding.code [ fhir:value "exact-start-end" ]; fhir:Coding.display [ fhir:value "Variant exact start and end" ] ] ]; fhir:Observation.component.valueRange [ fhir:Range.low [ fhir:Quantity.value [ fhir:value "55227978"^^xsd:decimal ] ]; fhir:Range.high [ fhir:Quantity.value [ fhir:value "55227979"^^xsd:decimal ] ] ] ]. <http://example.org/fhir/MolecularSequence/sequence-1-pgx-example> a fhir:MolecularSequence; fhir:Resource.id [ fhir:value "sequence-1-pgx-example"]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: sequence-1-pgx-example</p><p><b>type</b>: dna</p><p><b>coordinateSystem</b>: 0</p><h3>ReferenceSeqs</h3><table class=\"grid\"><tr><td>-</td><td><b>Orientation</b></td><td><b>ReferenceSeqId</b></td><td><b>WindowStart</b></td><td><b>WindowEnd</b></td></tr><tr><td>*</td><td>sense</td><td>NG-007726.3 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.ncbi.nlm.nih.gov/nuccore code 'NG-007726.3' = 'NG-007726.3)</span></td><td>55227970</td><td>55227980</td></tr></table></div>" ]; fhir:MolecularSequence.type [ fhir:value "dna"]; fhir:MolecularSequence.coordinateSystem [ fhir:value "0"^^xsd:integer]; fhir:MolecularSequence.referenceSeq [ fhir:MolecularSequence.referenceSeq.orientation [ fhir:value "sense" ]; fhir:MolecularSequence.referenceSeq.referenceSeqId [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.ncbi.nlm.nih.gov/nuccore" ]; fhir:Coding.code [ fhir:value "NG-007726.3" ] ] ]; fhir:MolecularSequence.referenceSeq.windowStart [ fhir:value "55227970"^^xsd:integer ]; fhir:MolecularSequence.referenceSeq.windowEnd [ fhir:value "55227980"^^xsd:integer ] ]. <http://example.org/fhir/MolecularSequence/sequence-2-pgx-example> a fhir:MolecularSequence; fhir:Resource.id [ fhir:value "sequence-2-pgx-example"]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: sequence-2-pgx-example</p><p><b>type</b>: dna</p><p><b>coordinateSystem</b>: 0</p><h3>ReferenceSeqs</h3><table class=\"grid\"><tr><td>-</td><td><b>Orientation</b></td><td><b>ReferenceSeqId</b></td><td><b>WindowStart</b></td><td><b>WindowEnd</b></td></tr><tr><td>*</td><td>sense</td><td>NG-007726.3 <span style=\"background: LightGoldenRodYellow\">(Details : {http://www.ncbi.nlm.nih.gov/nuccore code 'NG-007726.3' = 'NG-007726.3)</span></td><td>55227970</td><td>55227980</td></tr></table></div>" ]; fhir:MolecularSequence.type [ fhir:value "dna"]; fhir:MolecularSequence.coordinateSystem [ fhir:value "0"^^xsd:integer]; fhir:MolecularSequence.referenceSeq [ fhir:MolecularSequence.referenceSeq.orientation [ fhir:value "sense" ]; fhir:MolecularSequence.referenceSeq.referenceSeqId [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.ncbi.nlm.nih.gov/nuccore" ]; fhir:Coding.code [ fhir:value "NG-007726.3" ] ] ]; fhir:MolecularSequence.referenceSeq.windowStart [ fhir:value "55227970"^^xsd:integer ]; fhir:MolecularSequence.referenceSeq.windowEnd [ fhir:value "55227980"^^xsd:integer ] ]. <http://example.org/fhir/Task/med-usage-impact-task-pgx-example> a fhir:Task; fhir:Resource.id [ fhir:value "med-usage-impact-task-pgx-example"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/task-med-chg"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/task-med-chg> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: med-usage-impact-task-pgx-example</p><p><b>meta</b>: </p><p><b>status</b>: requested</p><p><b>intent</b>: proposal</p><p><b>code</b>: Any Increase does Recommendation Text from the provider <span style=\"background: LightGoldenRodYellow\">(Details : {LOINC code 'LA26423-6' = 'Increase dose', given as 'Increase dose'})</span></p><p><b>description</b>: Any Increase does Recommendation Text from the provider</p><p><b>focus</b>: <a href=\"MedicationStatement/current-med-example\">MedicationStatement/current-med-example</a></p><p><b>for</b>: <a href=\"Patient/patient\">Patient/patient</a></p><p><b>reasonReference</b>: <a href=\"Observation/med-impact-pgx-example\">Observation/med-impact-pgx-example</a></p></div>" ]; fhir:Task.status [ fhir:value "requested"]; fhir:Task.intent [ fhir:value "proposal"]; fhir:Task.code [ fhir:CodeableConcept.coding [ fhir:index 0; a loinc:LA26423-6; fhir:Coding.system [ fhir:value "http://loinc.org" ]; fhir:Coding.code [ fhir:value "LA26423-6" ]; fhir:Coding.display [ fhir:value "Increase dose" ] ]; fhir:CodeableConcept.text [ fhir:value "Any Increase does Recommendation Text from the provider" ] ]; fhir:Task.description [ fhir:value "Any Increase does Recommendation Text from the provider"]; fhir:Task.focus [ fhir:Reference.reference [ fhir:value "MedicationStatement/current-med-example" ] ]; fhir:Task.for [ fhir:Reference.reference [ fhir:value "Patient/patient" ] ]; fhir:Task.reasonReference [ fhir:Reference.reference [ fhir:value "Observation/med-impact-pgx-example" ] ]. <http://example.org/fhir/MedicationStatement/current-med-example> a fhir:MedicationStatement; fhir:Resource.id [ fhir:value "current-med-example"]; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/medicationstatement"; fhir:index 0; fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/medicationstatement> ] ]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: current-med-example</p><p><b>meta</b>: </p><p><b>status</b>: unknown</p><p><b>medication</b>: mercaptopurine <span style=\"background: LightGoldenRodYellow\">(Details : {RxNorm code '103' = 'mercaptopurine', given as 'mercaptopurine'})</span></p><p><b>subject</b>: <a href=\"Patient/patient\">Patient/patient</a></p></div>" ]; fhir:MedicationStatement.status [ fhir:value "unknown"]; fhir:MedicationStatement.medicationCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ]; fhir:Coding.code [ fhir:value "103" ]; fhir:Coding.display [ fhir:value "mercaptopurine" ] ] ]; fhir:MedicationStatement.subject [ fhir:Reference.reference [ fhir:value "Patient/patient" ] ]. # - ontology header ------------------------------------------------------------ a owl:Ontology; owl:imports fhir:fhir.ttl.
IG © 2017+ HL7 International Clinical Genomics Work Group. Package hl7.fhir.uv.genomics-reporting#1.0.0 based on FHIR 4.0.1. Generated 2019-11-20
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