This page is part of the Genetic Reporting Implementation Guide (v1.1.0: STU 2 Ballot 1) based on FHIR R4. The current version which supercedes this version is 2.0.0. For a full list of available versions, see the Directory of published versions
<Observation xmlns="http://hl7.org/fhir">
<id value="TherapeuticImplicationExample1"/>
<meta>
<profile
value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/therapeutic-implication"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative</b></p><p></p><p><b>category</b>: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes: {http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes therapeutic-implication}">Therapeutic Implication</span></p><p><b>derivedFrom</b>: <a href="Observation-GenotypeExample1.html">Generated Summary: <span title="Codes: {http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span>; <span title="Codes: {http://loinc.org 84413-4}">Genotype display name</span>; effective: 2018; <span title="Codes: {http://www.ncbi.nlm.nih.gov/clinvar 14909}">HLA-B*15:02</span></a></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 83009-1}">Genetic variation's effect on high-risk allele</span></p><p><b>value</b>: <span title="Codes: {http://loinc.org LA19541-4}">High risk</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes: {http://loinc.org 51963-7}">Medication assessed</span></p><p><b>value</b>: <span title="Codes: {http://www.nlm.nih.gov/research/umls/rxnorm 2002}">Carbamazepine</span></p></blockquote></div>
</text>
<status value="final"/>
<category>
<coding>
<system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
</coding>
</category>
<code>
<coding>
<system
value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes"/>
<code value="therapeutic-implication"/>
</coding>
</code>
<derivedFrom>
<reference value="Observation/GenotypeExample1"/>
</derivedFrom>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="83009-1"/>
<display value="Genetic variation's effect on high-risk allele"/>
</coding>
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<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="LA19541-4"/>
<display value="High risk"/>
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</valueCodeableConcept>
</component>
<component>
<code>
<coding>
<system value="http://loinc.org"/>
<code value="51963-7"/>
<display value="Medication assessed"/>
</coding>
</code>
<valueCodeableConcept>
<coding>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2002"/>
<display value="Carbamazepine"/>
</coding>
</valueCodeableConcept>
</component>
</Observation>