Genomics Reporting Implementation Guide
3.0.0-ballot - Ballot International flag

This page is part of the Genetic Reporting Implementation Guide (v3.0.0-ballot: STU 3 Ballot 1) based on FHIR (HL7® FHIR® Standard) R4. The current version which supersedes this version is 2.0.0. For a full list of available versions, see the Directory of published versions

CodeSystem: ClinVar Evidence Level Example Codes

Official URL: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/clinvar-evidence-level-custom-cs Version: 3.0.0-ballot
Active as of 2023-12-18 Computable Name: ClinVarEvidenceLevelCustomCS

ClinVar contains examples of evidence level concepts that are not conflated with clinical significance. These can be found on ClinVar https://www.ncbi.nlm.nih.gov/clinvar/docs/review_status/ . These examples are informational only, for copyright information contact the relevant source.

This Code system is referenced in the content logical definition of the following value sets:

This case-sensitive code system http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/clinvar-evidence-level-custom-cs defines the following codes:

CodeDisplayDefinition
4-star 4 starSupported by practice guideline
3-star 3 starSupported by expert panel review
2-star 2 starSupported by submission by multiple-submitters with documentation of criteria for assertion
1-star 1 starSingle submitter providing interpretation and documentation of criteria for assertion
no-star no starsubmitted, no evidence