Genomics Reporting Implementation Guide
2.0.0 - trial-use

This page is part of the Genetic Reporting Implementation Guide (v2.0.0: STU 2) based on FHIR R4. This is the current published version. For a full list of available versions, see the Directory of published versions

CodeSystem: ClinVar Evidence Level Example Codes

Summary

Defining URL:http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/clinvar-evidence-level-custom-cs
Version:2.0.0
Name:ClinVarEvidenceLevelCustomCS
Title:ClinVar Evidence Level Example Codes
Status:Active as of 2022-05-09 04:59:16+0000
Definition:

ClinVar contains examples of evidence level concepts that are not conflated with clinical significance. These can be found on ClinVar https://www.ncbi.nlm.nih.gov/clinvar/docs/review_status/ . These examples are informational only, for copyright information contact the relevant source.

Publisher:HL7 Clinical Genomics Working Group
Content:Complete: All the concepts defined by the code system are included in the code system resource
Source Resource:XML / JSON / Turtle

This Code system is referenced in the content logical definition of the following value sets:

This code system http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/clinvar-evidence-level-custom-cs defines the following codes:

CodeDisplayDefinition
4-star 4 starSupported by practice guideline
3-star 3 starSupported by expert panel review
2-star 2 starSupported by submission by multiple-submitters with documentation of criteria for assertion
1-star 1 starSingle submitter providing interpretation and documentation of criteria for assertion
no-star no starsubmitted, no evidence