Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot - ballot
This page is part of the Evidence Based Medicine on FHIR Implementation Guide (v1.0.0-ballot: STU1 Ballot 1) based on FHIR (HL7® FHIR® Standard) v5.0.0. . For a full list of available versions, see the Directory of published versions
| Active as of 2023-12-17 |
{
"resourceType" : "Evidence",
"id" : "179588",
"meta" : {
"versionId" : "6",
"lastUpdated" : "2023-12-08T13:32:26.958Z",
"profile" : [
🔗 "http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution"
]
},
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Evidence</b><a name=\"179588\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Evidence "179588" Version "6" Updated "2023-12-08 13:32:26+0000" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-net-effect-contribution.html\">NetEffectContribution</a></p></div><p><b>StructureDefinition Work Group</b>: cds</p><p><b>url</b>: <code>https://fevir.net/resources/Evidence/179588</code></p><p><b>identifier</b>: FEvIR Object Identifier:\u00a0179588</p><p><b>version</b>: 1.0.0-ballot</p><p><b>name</b>: NetEffectContribution_Remission_of_diabetes_for_Example_for_GIN_2022</p><p><b>title</b>: NetEffectContribution: Remission of diabetes for Example for GIN 2022</p><p><b>status</b>: active</p><p><b>date</b>: 2023-12-17 16:55:23+0000</p><p><b>publisher</b>: HL7 International / Clinical Decision Support</p><p><b>contact</b>: HL7 International / Clinical Decision Support: <a href=\"http://www.hl7.org/Special/committees/dss\">http://www.hl7.org/Special/committees/dss</a></p><p><b>author</b>: Brian S. Alper: </p><h3>UseContexts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Evidence Communication (Details: https://fevir.net/resources/CodeSystem/179423 code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')</td><td>ComparativeEvidence <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-179423.html\">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#ComparativeEvidence)</span></td></tr><tr><td style=\"display: none\">*</td><td>Evidence Communication (Details: https://fevir.net/resources/CodeSystem/179423 code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')</td><td>NetEffectContribution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-179423.html\">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#NetEffectContribution)</span></td></tr></table><p><b>copyright</b>: https://creativecommons.org/licenses/by-nc-sa/4.0/</p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Citation</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>cite-as</td><td>NetEffectContribution: Remission of diabetes for Example for GIN 2022 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179588. Revised 2023-12-06. Available at: https://fevir.net/resources/Evidence/179588. Computable resource at: https://fevir.net/resources/Evidence/179588.</td><td> </td></tr><tr><td style=\"display: none\">*</td><td>amended-with</td><td> </td><td><a href=\"ArtifactAssessment-104193.html\">ArtifactAssessment/104193: Outcome Importance Rating (default value 5) of Remission of diabetes</a></td></tr></table><p><b>description</b>: 2.15 (1.33 to 3.26) - example showing statistic.extension:modelExpression</p><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: population</p><p><b>description</b>: Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n\u2009=\u20092109) with severe obesity assessed (221 patients excluded and 1888 patients included).</p><p><b>note</b>: population</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#population "population")</span></p><p><b>observed</b>: <a href=\"Group-178427.html\">Group/178427: StudyGroup: Severely Obese Adults 2018 Norwegian Cohort</a> "Severely_Obese_Adults_2018_Norwegian_Cohort"</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: exposure</p><p><b>VariableDefinitionComparatorCategory</b>: no bariatric surgery</p><p><b>description</b>: comparison groups of bariatric surgery vs. no bariatric surgery</p><p><b>note</b>: exposure</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#exposure "exposure")</span></p><p><b>observed</b>: <a href=\"EvidenceVariable-172427.html\">EvidenceVariable/172427: GroupAssignment: Bariatric Surgery vs. no bariatric surgery</a> "GroupAssignment_Bariatric_Surgery_vs_no_bariatric_surgery"</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: outcome</p><p><b>description</b>: Remission of diabetes</p><p><b>note</b>: outcome</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#measuredVariable "measured variable")</span></p><p><b>observed</b>: <a href=\"EvidenceVariable-104117.html\">EvidenceVariable/104117: OutcomeVariable: Remission of diabetes</a> "OutcomeVariable_Remission_of_diabetes"</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: covariate</p><p><b>VariableDefinitionRoleSubtype</b>: Relative importance multiplier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-179423.html\">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#importance-multiplier)</span></p><p><b>description</b>: Relative Importance Multiplier</p><p><b>note</b>: covariate</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#confounder "confounder")</span></p><p><b>observed</b>: <span>: Relative Importance Multiplier</span></p></blockquote><blockquote><p><b>statistic</b></p><p><b>StatisticModelExpression</b>: <code>Evidence[id='104121'].statistic[statisticType='Relative Risk'] * Evidence[id='104396'].statistic[statisticType='Proportion'] * $this.relatedArtifact[type=#amended-with].resourceReference(processOutcomeImportance)</code>(<b>Net effect contribution analysis</b>"risk difference (relative risk x control event rate) multiplied by relative importance multiplier (defined in OutcomeImportance Profile) -- expression is pseudocode to demonstrate the concept")</p><p><b>description</b>: risk difference 2.15 (95% CI 1.33 to 3.26)</p><p><b>statisticType</b>: Risk Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-181513.html\">Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide</a>#STATO:0000424)</span></p><p><b>quantity</b>: 2.15</p><h3>AttributeEstimates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Description</b></td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>95% CI 1.33 to 3.26</td><td>confidence interval <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-181513.html\">Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide</a>#STATO:0000196)</span></td><td>0.95</td><td>1.33-3.26</td></tr></table><h3>ModelCharacteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Net effect contribution analysis <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-181513.html\">Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide</a>#TBD:net-effect-contribution-analysis)</span></td></tr></table></blockquote></div>"
},
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
"valueCode" : "cds"
}
],
"url" : "https://fevir.net/resources/Evidence/179588",
"identifier" : [
{
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
"code" : "ACSN",
"display" : "Accession ID"
}
],
"text" : "FEvIR Object Identifier"
},
"system" : "https://fevir.net",
"value" : "179588",
"assigner" : {
"display" : "Computable Publishing LLC"
}
}
],
"version" : "1.0.0-ballot",
"name" : "NetEffectContribution_Remission_of_diabetes_for_Example_for_GIN_2022",
"title" : "NetEffectContribution: Remission of diabetes for Example for GIN 2022",
"status" : "active",
"date" : "2023-12-17T16:55:23+00:00",
"publisher" : "HL7 International / Clinical Decision Support",
"contact" : [
{
"name" : "HL7 International / Clinical Decision Support",
"telecom" : [
{
"system" : "url",
"value" : "http://www.hl7.org/Special/committees/dss"
}
]
}
],
"author" : [
{
"name" : "Brian S. Alper"
}
],
"useContext" : [
{
"code" : {
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "evidence-communication",
"display" : "Evidence Communication"
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "ComparativeEvidence",
"display" : "ComparativeEvidence"
}
]
}
},
{
"code" : {
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "evidence-communication",
"display" : "Evidence Communication"
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "NetEffectContribution",
"display" : "NetEffectContribution"
}
]
}
}
],
"copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/",
"relatedArtifact" : [
{
"type" : "cite-as",
"citation" : "NetEffectContribution: Remission of diabetes for Example for GIN 2022 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179588. Revised 2023-12-06. Available at: https://fevir.net/resources/Evidence/179588. Computable resource at: https://fevir.net/resources/Evidence/179588."
},
{
"type" : "amended-with",
"resourceReference" : {
🔗 "reference" : "ArtifactAssessment/104193",
"type" : "ArtifactAssessment",
"display" : "Outcome Importance Rating (default value 5) of Remission of diabetes"
}
}
],
"description" : "2.15 (1.33 to 3.26) - example showing statistic.extension:modelExpression",
"variableDefinition" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code",
"valueCode" : "population"
}
],
"description" : "Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n\u2009=\u20092109) with severe obesity assessed (221 patients excluded and 1888 patients included).",
"note" : [
{
"text" : "population"
}
],
"variableRole" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/variable-role",
"code" : "population",
"display" : "population"
}
],
"text" : "Use extension:variableRoleCode instead."
},
"observed" : {
🔗 "reference" : "Group/178427",
"type" : "Group",
"display" : "StudyGroup: Severely Obese Adults 2018 Norwegian Cohort"
}
},
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code",
"valueCode" : "exposure"
},
{
"url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-comparator-category",
"valueString" : "no bariatric surgery"
}
],
"description" : "comparison groups of bariatric surgery vs. no bariatric surgery",
"note" : [
{
"text" : "exposure"
}
],
"variableRole" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/variable-role",
"code" : "exposure",
"display" : "exposure"
}
],
"text" : "Use extension:variableRoleCode instead."
},
"observed" : {
🔗 "reference" : "EvidenceVariable/172427",
"type" : "EvidenceVariable",
"display" : "GroupAssignment: Bariatric Surgery vs. no bariatric surgery"
}
},
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code",
"valueCode" : "outcome"
}
],
"description" : "Remission of diabetes",
"note" : [
{
"text" : "outcome"
}
],
"variableRole" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/variable-role",
"code" : "measuredVariable",
"display" : "measured variable"
}
],
"text" : "Use extension:variableRoleCode instead."
},
"observed" : {
🔗 "reference" : "EvidenceVariable/104117",
"type" : "EvidenceVariable",
"display" : "OutcomeVariable: Remission of diabetes"
}
},
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code",
"valueCode" : "covariate"
},
{
"url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-role-subtype",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/179423",
"code" : "importance-multiplier",
"display" : "Relative importance multiplier"
}
]
}
}
],
"description" : "Relative Importance Multiplier",
"note" : [
{
"text" : "covariate"
}
],
"variableRole" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/variable-role",
"code" : "confounder",
"display" : "confounder"
}
],
"text" : "Use extension:variableRoleCode instead."
},
"observed" : {
"display" : "Relative Importance Multiplier"
}
}
],
"statistic" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/statistic-model-expression",
"valueExpression" : {
"description" : "risk difference (relative risk x control event rate) multiplied by relative importance multiplier (defined in OutcomeImportance Profile) -- expression is pseudocode to demonstrate the concept",
"name" : "Net effect contribution analysis",
"expression" : "Evidence[id='104121'].statistic[statisticType='Relative Risk'] * Evidence[id='104396'].statistic[statisticType='Proportion'] * $this.relatedArtifact[type=#amended-with].resourceReference(processOutcomeImportance)"
}
}
],
"description" : "risk difference 2.15 (95% CI 1.33 to 3.26)",
"statisticType" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/181513",
"code" : "STATO:0000424",
"display" : "Risk Difference"
}
]
},
"quantity" : {
"value" : 2.15
},
"attributeEstimate" : [
{
"description" : "95% CI 1.33 to 3.26",
"type" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/181513",
"code" : "STATO:0000196",
"display" : "confidence interval"
}
]
},
"level" : 0.95,
"range" : {
"low" : {
"value" : 1.33
},
"high" : {
"value" : 3.26
}
}
}
],
"modelCharacteristic" : [
{
"code" : {
"coding" : [
{
"system" : "https://fevir.net/resources/CodeSystem/181513",
"code" : "TBD:net-effect-contribution-analysis",
"display" : "Net effect contribution analysis"
}
]
}
}
]
}
]
}
IG © 2022+ HL7 International / Clinical Decision Support. Package hl7.fhir.uv.ebm#1.0.0-ballot based on FHIR 5.0.0. Generated 2023-12-17
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