This page is part of the HL7 FHIR Implementation Guide: minimal Common Oncology Data Elements (mCODE) Release 1 - US Realm | STU1 (v0.9.1: STU 1 Ballot 1) based on FHIR R4. The current version which supercedes this version is 2.0.0. For a full list of available versions, see the Directory of published versions

• Narrative
• XML
• JSON
• Turtle

Example: mCODEGeneticVariantFoundExample01

<Observation xmlns="http://hl7.org/fhir">
  <id value="mCODEGeneticVariantFoundExample01"/>
  <meta>
    <profile
             value="http://hl7.org/fhir/us/mcode/StructureDefinition/onco-core-GeneticVariantFound"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
			<p>
				<b>*** mCODE Example: Genetic Variant Assessment ***</b>
			</p>
			<p>
				<b>Patient identifier</b>: m123</p>
			<p><b>Name</b>: John B. Anyperson </p>
			<p>
				<b>Test date</b>: April 1, 2019</p>
			<p>
				<b>Genomic source class [Type]</b>: Somatic</p>
			<p>
				<b>Variant HGVS name</b>: NM_000455.4:c.921-1G>C</p>
			<p><b>Variant common name</b>: G242E</p>
			</div>
  </text>
  <status value="final"/>
  <category>
    <coding>
      <system value="http://terminology.hl7.org/CodeSystem/observation-category"/>
      <code value="laboratory"/>
    </coding>
  </category>
  <code>
    <coding>
      <system value="http://loinc.org"/>
      <code value="69548-6"/>
      <display value="Genetic variant assessment"/>
    </coding>
  </code>
  <subject>
    <reference value="Patient/mCODEPatientExample01"/>
    <display value="John B. Anyperson"/>
  </subject>
  <effectiveDateTime value="2019-04-01"/>
  <method>
    <coding>
      <system value="http://ncit.nci.nih.gov"/>
      <code value="C101293"/>
      <display value="Next Generation Sequencing"/>
    </coding>
  </method>
  <component>
    <code>
      <coding>
        <system value="http://loinc.org"/>
        <code value="48002-0"/>
        <display value="Genomic source class [Type]"/>
      </coding>
    </code>
    <valueCodeableConcept>
      <coding>
        <system value="http://loinc.org"/>
        <code value="LA6684-0"/>
        <display value="Somatic"/>
      </coding>
      <text value="Somatic"/>
    </valueCodeableConcept>
  </component>
  <component>
    <code>
      <coding>
        <system value="http://loinc.org"/>
        <code value="48003-8"/>
        <display value="DNA sequence variation identifier [Identifier]"/>
      </coding>
    </code>
    <valueCodeableConcept>
      <coding>
        <system value="http://www.ncbi.nlm.nih.gov/clinvar/"/>
        <code value="619728"/>
        <display value="NM_000455.4(STK11):c.725G&gt;A (p.Gly242Glu)"/>
      </coding>
      <text value="NM_000455.4(STK11):c.725G&gt;A (p.Gly242Glu)"/>
    </valueCodeableConcept>
  </component>
  <component>
    <code>
      <coding>
        <system value="http://loinc.org"/>
        <code value="82154-6"/>
        <display value="Genomic structural variant name"/>
      </coding>
    </code>
    <valueString value="NM_000455.4:c.725G&gt;A"/>
  </component>
  <component>
    <code>
      <coding>
        <system value="http://loinc.org"/>
        <code value="47998-0"/>
        <display value="DNA sequence variation display name [Text] Narrative"/>
      </coding>
    </code>
    <valueString value="G242E"/>
  </component>
</Observation>