This page is part of the HL7 FHIR Implementation Guide: minimal Common Oncology Data Elements (mCODE) Release 1 - US Realm | STU1 (v0.9.1: STU 1 Ballot 1) based on FHIR (HL7® FHIR® Standard) R4. The current version which supersedes this version is 4.0.0. For a full list of available versions, see the Directory of published versions

• Narrative
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Example: mCODEGeneticVariantFoundExample01

{
  "resourceType" : "Observation",
  "id" : "mCODEGeneticVariantFoundExample01",
  "meta" : {
    "profile" : [
      "http://hl7.org/fhir/us/mcode/StructureDefinition/onco-core-GeneticVariantFound"
    ]
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n\t\t\t<p>\n\t\t\t\t<b>*** mCODE Example: Genetic Variant Assessment ***</b>\n\t\t\t</p>\n\t\t\t<p>\n\t\t\t\t<b>Patient identifier</b>: m123</p>\n\t\t\t<p><b>Name</b>: John B. Anyperson </p>\n\t\t\t<p>\n\t\t\t\t<b>Test date</b>: April 1, 2019</p>\n\t\t\t<p>\n\t\t\t\t<b>Genomic source class [Type]</b>: Somatic</p>\n\t\t\t<p>\n\t\t\t\t<b>Variant HGVS name</b>: NM_000455.4:c.921-1G>C</p>\n\t\t\t<p><b>Variant common name</b>: G242E</p>\n\t\t\t</div>"
  },
  "status" : "final",
  "category" : [
    {
      "coding" : [
        {
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory"
        }
      ]
    }
  ],
  "code" : {
    "coding" : [
      {
        "system" : "http://loinc.org",
        "code" : "69548-6",
        "display" : "Genetic variant assessment"
      }
    ]
  },
  "subject" : {
    "reference" : "Patient/mCODEPatientExample01",
    "display" : "John B. Anyperson"
  },
  "effectiveDateTime" : "2019-04-01",
  "method" : {
    "coding" : [
      {
        "system" : "http://ncit.nci.nih.gov",
        "code" : "C101293",
        "display" : "Next Generation Sequencing"
      }
    ]
  },
  "component" : [
    {
      "code" : {
        "coding" : [
          {
            "system" : "http://loinc.org",
            "code" : "48002-0",
            "display" : "Genomic source class [Type]"
          }
        ]
      },
      "valueCodeableConcept" : {
        "coding" : [
          {
            "system" : "http://loinc.org",
            "code" : "LA6684-0",
            "display" : "Somatic"
          }
        ],
        "text" : "Somatic"
      }
    },
    {
      "code" : {
        "coding" : [
          {
            "system" : "http://loinc.org",
            "code" : "48003-8",
            "display" : "DNA sequence variation identifier [Identifier]"
          }
        ]
      },
      "valueCodeableConcept" : {
        "coding" : [
          {
            "system" : "http://www.ncbi.nlm.nih.gov/clinvar/",
            "code" : "619728",
            "display" : "NM_000455.4(STK11):c.725G>A (p.Gly242Glu)"
          }
        ],
        "text" : "NM_000455.4(STK11):c.725G>A (p.Gly242Glu)"
      }
    },
    {
      "code" : {
        "coding" : [
          {
            "system" : "http://loinc.org",
            "code" : "82154-6",
            "display" : "Genomic structural variant name"
          }
        ]
      },
      "valueString" : "NM_000455.4:c.725G>A"
    },
    {
      "code" : {
        "coding" : [
          {
            "system" : "http://loinc.org",
            "code" : "47998-0",
            "display" : "DNA sequence variation display name [Text] Narrative"
          }
        ]
      },
      "valueString" : "G242E"
    }
  ]
}