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Certainty Rating of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19 (id = "example-certainty-rating")
<?xml version="1.0" encoding="UTF-8"?>
<ArtifactAssessment xmlns="http://hl7.org/fhir">
<id value="example-certainty-rating"/>
<text> <status value="generated"/> <div xmlns="http://www.w3.org/1999/xhtml"><p> <b> Generated Narrative: ArtifactAssessment</b> <a name="example-certainty-rating"> </a> </p> <div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border:
1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource ArtifactAssessment "example-certainty-rating" </p> </div> <p> <b> identifier</b> : FEvIR Object Identifier: 27756</p> <p> <b> date</b> : 2021-11-02T14:48:59.89Z</p> <p> <b> copyright</b> : https://creativecommons.org/licenses/by-nc-sa/4.0/</p> <p> <b> artifact</b> : <a href="broken-link.html">Evidence/18812: Critically appraised summary of all-cause mortality in meta-analysis
of RCTs of heparin for moderately ill patients with COVID-19</a> </p> <blockquote> <p> <b> content</b> </p> <p> <b> informationType</b> : rating</p> <p> <b> summary</b> : serious concerns with risk of bias, inconsistency, and imprecision</p> <p> <b> type</b> : Overall certainty <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-type.html">Evidence Certainty Type</a> #Overall)</span> </p> <p> <b> classifier</b> : Very low quality <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-rating.html">Evidence Certainty Rating</a> #very-low)</span> </p> <p> <b> author</b> : <span> : Brian S. Alper</span> </p> <p> <b> freeToShare</b> : true</p> <h3> Components</h3> <table class="grid"><tr> <td> -</td> <td> <b> InformationType</b> </td> <td> <b> Summary</b> </td> <td> <b> Type</b> </td> <td> <b> Classifier</b> </td> <td> <b> Author</b> </td> </tr> <tr> <td> *</td> <td> rating</td> <td> risk of bias in both included trials</td> <td> Risk of bias <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-type.html">Evidence Certainty Type</a> #RiskOfBias)</span> </td> <td> serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-rating.html">Evidence Certainty Rating</a> #serious-concern)</span> </td> <td> <span> : Brian S. Alper</span> </td> </tr> <tr> <td> *</td> <td> rating</td> <td> high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial
effect estimates barely overlapping</td> <td> Inconsistency <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-type.html">Evidence Certainty Type</a> #Inconsistency)</span> </td> <td> serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-rating.html">Evidence Certainty Rating</a> #serious-concern)</span> </td> <td> <span> : Brian S. Alper</span> </td> </tr> <tr> <td> *</td> <td> rating</td> <td> </td> <td> Indirectness <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-type.html">Evidence Certainty Type</a> #Indirectness)</span> </td> <td> no serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-rating.html">Evidence Certainty Rating</a> #no-concern)</span> </td> <td> <span> : Brian S. Alper</span> </td> </tr> <tr> <td> *</td> <td> rating</td> <td> 95% confidence interval includes both large effects and no effects</td> <td> Imprecision <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-type.html">Evidence Certainty Type</a> #Imprecision)</span> </td> <td> serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-rating.html">Evidence Certainty Rating</a> #serious-concern)</span> </td> <td> <span> : Brian S. Alper</span> </td> </tr> <tr> <td> *</td> <td> rating</td> <td> </td> <td> Publication bias <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-type.html">Evidence Certainty Type</a> #PublicationBias)</span> </td> <td> no serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="codesystem-certainty-rating.html">Evidence Certainty Rating</a> #no-concern)</span> </td> <td> <span> : Brian S. Alper</span> </td> </tr> </table> </blockquote> </div> </text> <identifier>
<type>
<text value="FEvIR Object Identifier"/>
</type>
<system value="https://fevir.net"/>
<value value="27756"/>
<assigner>
<display value="Computable Publishing LLC"/>
</assigner>
</identifier>
<date value="2021-11-02T14:48:59.890Z"/>
<copyright value="https://creativecommons.org/licenses/by-nc-sa/4.0/"/>
<artifactReference>
<reference value="Evidence/18812"/>
<type value="Evidence"/>
<display value="Critically appraised summary of all-cause mortality in meta-analysis of RCTs of
heparin for moderately ill patients with COVID-19"/>
</artifactReference>
<content>
<informationType value="rating"/>
<summary value="serious concerns with risk of bias, inconsistency, and imprecision"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="Overall"/>
<display value="Overall certainty"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="very-low"/>
<display value="Very low quality"/>
</coding>
</classifier>
<author>
<display value="Brian S. Alper"/>
</author>
<freeToShare value="true"/>
<component>
<informationType value="rating"/>
<summary value="risk of bias in both included trials"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="RiskOfBias"/>
<display value="Risk of bias"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="serious-concern"/>
<display value="serious concern"/>
</coding>
</classifier>
<author>
<display value="Brian S. Alper"/>
</author>
</component>
<component>
<informationType value="rating"/>
<summary value="high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial
effect estimates barely overlapping"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="Inconsistency"/>
<display value="Inconsistency"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="serious-concern"/>
<display value="serious concern"/>
</coding>
</classifier>
<author>
<display value="Brian S. Alper"/>
</author>
</component>
<component>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="Indirectness"/>
<display value="Indirectness"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="no-concern"/>
<display value="no serious concern"/>
</coding>
</classifier>
<author>
<display value="Brian S. Alper"/>
</author>
</component>
<component>
<informationType value="rating"/>
<summary value="95% confidence interval includes both large effects and no effects"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="Imprecision"/>
<display value="Imprecision"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="serious-concern"/>
<display value="serious concern"/>
</coding>
</classifier>
<author>
<display value="Brian S. Alper"/>
</author>
</component>
<component>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="PublicationBias"/>
<display value="Publication bias"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="no-concern"/>
<display value="no serious concern"/>
</coding>
</classifier>
<author>
<display value="Brian S. Alper"/>
</author>
</component>
</content>
</ArtifactAssessment>
Usage note: every effort has been made to ensure that the
examples are correct and useful, but they are not a normative part
of the specification.
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