This page is part of the FHIR Specification (v3.3.0: R4 Ballot 2). The current version which supercedes this version is 5.0.0. For a full list of available versions, see the Directory of published versions

8.18 Resource SubstanceSpecification - Content

Biomedical Research and Regulation

Work Group

Maturity Level: 0

Draft

Compartments: Not linked to any defined compartments

The detailed description of a substance, typically at a level beyond what is used for prescribing.

8.18.1 Scope and Usage

Any pharmaceutical product or combination of pharmaceutical products that may be administered to human beings (or animals) for treating or preventing disease, with the aim/purpose of making a medical diagnosis or to restore, correct or modify physiological functions.

A Medicinal Product may contain in the packaging one or more manufactured items and one or more pharmaceutical products. In certain regions a Medicinal Product may also be defined as any substance or combination of substances which may be used to make a medical diagnosis.

This applies to proprietary medicinal products for human use intended to be placed on the market and to industrially manufactured medicinal products, the marketing of which has been authorised by a Medicines Regulatory Agency. However, the provisions do not apply to: i) medicinal products prepared according to prescription (e.g. prepared in a pharmacy from a prescription intended for a specific patient), ii) medicinal products prepared in accordance with an official formula (e.g. prepared in a pharmacy in accordance with the instructions in a pharmacopoeia and intended to be given direct to the patient by the pharmacy), iii) medicinal products intended for research and development trials (see 11.2 Investigational Medicinal Product) and to iv) intermediate products intended for subsequent processing by an authorised manufacturer. [from ENV 13607 and ENV 12610]

This resource is referenced by MedicinalProductClinicals and SubstanceReferenceInformation

Structure

Name	Flags	Card.	Type	Description & Constraints
SubstanceSpecification	Σ D		DomainResource	The detailed description of a substance, typically at a level beyond what is used for prescribing Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension
comment	Σ	0..1	string	Textual comment
stoichiometric	Σ	0..1	boolean	Chemicals may be stoichiometric or non-stoichiometric
identifier	Σ	0..1	Identifier	Identifier by which this substance is known
type	Σ	0..1	CodeableConcept	High level categorization, e.g. polymer or nucleic acid
referenceSource	Σ	0..*	string	Supporting literature
moiety	Σ	0..*	BackboneElement	Moiety, for structural modifications
role	Σ	0..1	CodeableConcept	Role that the moiety is playing
identifier	Σ	0..1	Identifier	Identifier by which this moiety substance is known
name	Σ	0..1	string	Textual name for this moiety substance
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type
molecularFormula	Σ	0..1	string	Molecular formula
amount	Σ	0..1	string	Quantitative value for this moiety
property	Σ	0..*	BackboneElement	General specifications for this substance, including how it is related to other substances
type	Σ	0..1	CodeableConcept	Description todo
name	Σ	0..1	CodeableConcept	Description todo
parameters	Σ	0..1	string	A field that should be used to capture parameters that were used in the measurement of a property
substanceId	Σ	0..1	Identifier	Identifier for a substance upon which a defining property depends
substanceName	Σ	0..1	string	Description todo
amount	Σ	0..1	string	Quantitative value for this property
referenceInformation	Σ	0..1	Reference(SubstanceReferenceInformation)	General information detailing this substance
structure	Σ	0..1	BackboneElement	Structural information
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type
molecularFormula	Σ	0..1	string	Molecular formula
molecularFormulaByMoiety	Σ	0..1	string	Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical. and each moiety separated by a dot
isotope	Σ	0..*	BackboneElement	Applicable for single substances that contain a radionuclide or a non-natural isotopic ratio
nuclideId	Σ	0..1	Identifier	Substance identifier for each non-natural or radioisotope
nuclideName	Σ	0..1	CodeableConcept	Substance name for each non-natural or radioisotope
substitutionType	Σ	0..1	CodeableConcept	The type of isotopic substitution present in a single substance
nuclideHalfLife	Σ	0..1	Quantity	Half life - for a non-natural nuclide
amount	Σ	0..1	string	Quantitative values for this isotope
molecularWeight	Σ	0..1	BackboneElement	The molecular weight or weight range (for proteins, polymers or nucleic acids)
method	Σ	0..1	CodeableConcept	The method by which the molecular weight was determined
type	Σ	0..1	CodeableConcept	Type of molecular weight such as exact, average (also known as. number average), weight average
amount	Σ	0..1	string	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field
molecularWeight	Σ	0..1	see molecularWeight	The molecular weight or weight range (for proteins, polymers or nucleic acids)
referenceSource	Σ	0..*	Reference(DocumentReference)	Supporting literature
structuralRepresentation	Σ	0..*	BackboneElement	Molectular structural representation
type	Σ	0..1	CodeableConcept	The type of structure (e.g. Full, Partial, Representative)
representation	Σ	0..1	string	The structural representation as text string in a format e.g. InChI, SMILES, MOLFILE, CDX
attachment	Σ	0..1	Attachment	An attached file with the structural representation
substanceCode	Σ	0..*	BackboneElement	Codes associated with the substance
code	Σ	0..1	CodeableConcept	The specific code
status	Σ	0..1	CodeableConcept	Status of the code assignment
statusDate	Σ	0..1	dateTime	The date at which the code status is changed as part of the terminology maintenance
comment	Σ	0..1	string	Any comment can be provided in this field, if necessary
referenceSource	Σ	0..*	string	Supporting literature
substanceName	Σ	0..*	BackboneElement	Names applicable to this substence
name	Σ	0..1	string	The actual name
type	Σ	0..1	CodeableConcept	Name type
language	Σ	0..*	CodeableConcept	Language of the name
domain	Σ	0..*	CodeableConcept	The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive
jurisdiction	Σ	0..*	CodeableConcept	The jurisdiction where this name applies
officialName	Σ	0..*	BackboneElement	Details of the official nature of this name
authority	Σ	0..1	CodeableConcept	Which authority uses this official name
status	Σ	0..1	CodeableConcept	The status of the official name
date	Σ	0..1	dateTime	Date of official name change
referenceSource	Σ	0..*	string	Supporting literature
molecularWeight	Σ	0..*	see molecularWeight	The molecular weight or weight range (for proteins, polymers or nucleic acids)
polymer	Σ	0..1	Reference(SubstancePolymer)	Data items specific to polymers
Documentation for this format

UML Diagram (Legend)

XML Template

<SubstanceSpecification xmlns="http://hl7.org/fhir"> 
 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <comment value="[string]"/><!-- 0..1 Textual comment -->
 <stoichiometric value="[boolean]"/><!-- 0..1 Chemicals may be stoichiometric or non-stoichiometric -->
 <identifier><!-- 0..1 Identifier Identifier by which this substance is known --></identifier>
 <type><!-- 0..1 CodeableConcept High level categorization, e.g. polymer or nucleic acid --></type>
 <referenceSource value="[string]"/><!-- 0..* Supporting literature -->
 <moiety>  <!-- 0..* Moiety, for structural modifications -->
  <role><!-- 0..1 CodeableConcept Role that the moiety is playing --></role>
  <identifier><!-- 0..1 Identifier Identifier by which this moiety substance is known --></identifier>
  <name value="[string]"/><!-- 0..1 Textual name for this moiety substance -->
  <stereochemistry><!-- 0..1 CodeableConcept Stereochemistry type --></stereochemistry>
  <opticalActivity><!-- 0..1 CodeableConcept Optical activity type --></opticalActivity>
  <molecularFormula value="[string]"/><!-- 0..1 Molecular formula -->
  <amount value="[string]"/><!-- 0..1 Quantitative value for this moiety -->
 </moiety>
 <property>  <!-- 0..* General specifications for this substance, including how it is related to other substances -->
  <type><!-- 0..1 CodeableConcept Description todo --></type>
  <name><!-- 0..1 CodeableConcept Description todo --></name>
  <parameters value="[string]"/><!-- 0..1 A field that should be used to capture parameters that were used in the measurement of a property -->
  <substanceId><!-- 0..1 Identifier Identifier for a substance upon which a defining property depends --></substanceId>
  <substanceName value="[string]"/><!-- 0..1 Description todo -->
  <amount value="[string]"/><!-- 0..1 Quantitative value for this property -->
 </property>
 <referenceInformation><!-- 0..1 Reference(SubstanceReferenceInformation) General information detailing this substance --></referenceInformation>
 <structure>  <!-- 0..1 Structural information -->
  <stereochemistry><!-- 0..1 CodeableConcept Stereochemistry type --></stereochemistry>
  <opticalActivity><!-- 0..1 CodeableConcept Optical activity type --></opticalActivity>
  <molecularFormula value="[string]"/><!-- 0..1 Molecular formula -->
  <molecularFormulaByMoiety value="[string]"/><!-- 0..1 Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical. and each moiety separated by a dot -->
  <isotope>  <!-- 0..* Applicable for single substances that contain a radionuclide or a non-natural isotopic ratio -->
   <nuclideId><!-- 0..1 Identifier Substance identifier for each non-natural or radioisotope --></nuclideId>
   <nuclideName><!-- 0..1 CodeableConcept Substance name for each non-natural or radioisotope --></nuclideName>
   <substitutionType><!-- 0..1 CodeableConcept The type of isotopic substitution present in a single substance --></substitutionType>
   <nuclideHalfLife><!-- 0..1 Quantity Half life - for a non-natural nuclide --></nuclideHalfLife>
   <amount value="[string]"/><!-- 0..1 Quantitative values for this isotope -->
   <molecularWeight>  <!-- 0..1 The molecular weight or weight range (for proteins, polymers or nucleic acids) -->
    <method><!-- 0..1 CodeableConcept The method by which the molecular weight was determined --></method>
    <type><!-- 0..1 CodeableConcept Type of molecular weight such as exact, average (also known as. number average), weight average --></type>
    <amount value="[string]"/><!-- 0..1 Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field -->
   </molecularWeight>
  </isotope>
  <molecularWeight><!-- 0..1 Content as for SubstanceSpecification.structure.isotope.molecularWeight The molecular weight or weight range (for proteins, polymers or nucleic acids) --></molecularWeight>
  <referenceSource><!-- 0..* Reference(DocumentReference) Supporting literature --></referenceSource>
  <structuralRepresentation>  <!-- 0..* Molectular structural representation -->
   <type><!-- 0..1 CodeableConcept The type of structure (e.g. Full, Partial, Representative) --></type>
   <representation value="[string]"/><!-- 0..1 The structural representation as text string in a format e.g. InChI, SMILES, MOLFILE, CDX -->
   <attachment><!-- 0..1 Attachment An attached file with the structural representation --></attachment>
  </structuralRepresentation>
 </structure>
 <substanceCode>  <!-- 0..* Codes associated with the substance -->
  <code><!-- 0..1 CodeableConcept The specific code --></code>
  <status><!-- 0..1 CodeableConcept Status of the code assignment --></status>
  <statusDate value="[dateTime]"/><!-- 0..1 The date at which the code status is changed as part of the terminology maintenance -->
  <comment value="[string]"/><!-- 0..1 Any comment can be provided in this field, if necessary -->
  <referenceSource value="[string]"/><!-- 0..* Supporting literature -->
 </substanceCode>
 <substanceName>  <!-- 0..* Names applicable to this substence -->
  <name value="[string]"/><!-- 0..1 The actual name -->
  <type><!-- 0..1 CodeableConcept Name type --></type>
  <language><!-- 0..* CodeableConcept Language of the name --></language>
  <domain><!-- 0..* CodeableConcept The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive --></domain>
  <jurisdiction><!-- 0..* CodeableConcept The jurisdiction where this name applies --></jurisdiction>
  <officialName>  <!-- 0..* Details of the official nature of this name -->
   <authority><!-- 0..1 CodeableConcept Which authority uses this official name --></authority>
   <status><!-- 0..1 CodeableConcept The status of the official name --></status>
   <date value="[dateTime]"/><!-- 0..1 Date of official name change -->
  </officialName>
  <referenceSource value="[string]"/><!-- 0..* Supporting literature -->
 </substanceName>
 <molecularWeight><!-- 0..* Content as for SubstanceSpecification.structure.isotope.molecularWeight The molecular weight or weight range (for proteins, polymers or nucleic acids) --></molecularWeight>
 <polymer><!-- 0..1 Reference(SubstancePolymer) Data items specific to polymers --></polymer>
</SubstanceSpecification>

JSON Template

{
  "resourceType" : "SubstanceSpecification",
  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "comment" : "<string>", // Textual comment
  "stoichiometric" : <boolean>, // Chemicals may be stoichiometric or non-stoichiometric
  "identifier" : { Identifier }, // Identifier by which this substance is known
  "type" : { CodeableConcept }, // High level categorization, e.g. polymer or nucleic acid
  "referenceSource" : ["<string>"], // Supporting literature
  "moiety" : [{ // Moiety, for structural modifications
    "role" : { CodeableConcept }, // Role that the moiety is playing
    "identifier" : { Identifier }, // Identifier by which this moiety substance is known
    "name" : "<string>", // Textual name for this moiety substance
    "stereochemistry" : { CodeableConcept }, // Stereochemistry type
    "opticalActivity" : { CodeableConcept }, // Optical activity type
    "molecularFormula" : "<string>", // Molecular formula
    "amount" : "<string>" // Quantitative value for this moiety
  }],
  "property" : [{ // General specifications for this substance, including how it is related to other substances
    "type" : { CodeableConcept }, // Description todo
    "name" : { CodeableConcept }, // Description todo
    "parameters" : "<string>", // A field that should be used to capture parameters that were used in the measurement of a property
    "substanceId" : { Identifier }, // Identifier for a substance upon which a defining property depends
    "substanceName" : "<string>", // Description todo
    "amount" : "<string>" // Quantitative value for this property
  }],
  "referenceInformation" : { Reference(SubstanceReferenceInformation) }, // General information detailing this substance
  "structure" : { // Structural information
    "stereochemistry" : { CodeableConcept }, // Stereochemistry type
    "opticalActivity" : { CodeableConcept }, // Optical activity type
    "molecularFormula" : "<string>", // Molecular formula
    "molecularFormulaByMoiety" : "<string>", // Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical. and each moiety separated by a dot
    "isotope" : [{ // Applicable for single substances that contain a radionuclide or a non-natural isotopic ratio
      "nuclideId" : { Identifier }, // Substance identifier for each non-natural or radioisotope
      "nuclideName" : { CodeableConcept }, // Substance name for each non-natural or radioisotope
      "substitutionType" : { CodeableConcept }, // The type of isotopic substitution present in a single substance
      "nuclideHalfLife" : { Quantity }, // Half life - for a non-natural nuclide
      "amount" : "<string>", // Quantitative values for this isotope
      "molecularWeight" : { // The molecular weight or weight range (for proteins, polymers or nucleic acids)
        "method" : { CodeableConcept }, // The method by which the molecular weight was determined
        "type" : { CodeableConcept }, // Type of molecular weight such as exact, average (also known as. number average), weight average
        "amount" : "<string>" // Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field
      }
    }],
    "molecularWeight" : { Content as for SubstanceSpecification.structure.isotope.molecularWeight }, // The molecular weight or weight range (for proteins, polymers or nucleic acids)
    "referenceSource" : [{ Reference(DocumentReference) }], // Supporting literature
    "structuralRepresentation" : [{ // Molectular structural representation
      "type" : { CodeableConcept }, // The type of structure (e.g. Full, Partial, Representative)
      "representation" : "<string>", // The structural representation as text string in a format e.g. InChI, SMILES, MOLFILE, CDX
      "attachment" : { Attachment } // An attached file with the structural representation
    }]
  },
  "substanceCode" : [{ // Codes associated with the substance
    "code" : { CodeableConcept }, // The specific code
    "status" : { CodeableConcept }, // Status of the code assignment
    "statusDate" : "<dateTime>", // The date at which the code status is changed as part of the terminology maintenance
    "comment" : "<string>", // Any comment can be provided in this field, if necessary
    "referenceSource" : ["<string>"] // Supporting literature
  }],
  "substanceName" : [{ // Names applicable to this substence
    "name" : "<string>", // The actual name
    "type" : { CodeableConcept }, // Name type
    "language" : [{ CodeableConcept }], // Language of the name
    "domain" : [{ CodeableConcept }], // The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive
    "jurisdiction" : [{ CodeableConcept }], // The jurisdiction where this name applies
    "officialName" : [{ // Details of the official nature of this name
      "authority" : { CodeableConcept }, // Which authority uses this official name
      "status" : { CodeableConcept }, // The status of the official name
      "date" : "<dateTime>" // Date of official name change
    }],
    "referenceSource" : ["<string>"] // Supporting literature
  }],
  "molecularWeight" : [{ Content as for SubstanceSpecification.structure.isotope.molecularWeight }], // The molecular weight or weight range (for proteins, polymers or nucleic acids)
  "polymer" : { Reference(SubstancePolymer) } // Data items specific to polymers
}

Turtle Template

@prefix fhir: <http://hl7.org/fhir/> .


[ a fhir:SubstanceSpecification;
  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:SubstanceSpecification.comment [ string ]; # 0..1 Textual comment
  fhir:SubstanceSpecification.stoichiometric [ boolean ]; # 0..1 Chemicals may be stoichiometric or non-stoichiometric
  fhir:SubstanceSpecification.identifier [ Identifier ]; # 0..1 Identifier by which this substance is known
  fhir:SubstanceSpecification.type [ CodeableConcept ]; # 0..1 High level categorization, e.g. polymer or nucleic acid
  fhir:SubstanceSpecification.referenceSource [ string ], ... ; # 0..* Supporting literature
  fhir:SubstanceSpecification.moiety [ # 0..* Moiety, for structural modifications
    fhir:SubstanceSpecification.moiety.role [ CodeableConcept ]; # 0..1 Role that the moiety is playing
    fhir:SubstanceSpecification.moiety.identifier [ Identifier ]; # 0..1 Identifier by which this moiety substance is known
    fhir:SubstanceSpecification.moiety.name [ string ]; # 0..1 Textual name for this moiety substance
    fhir:SubstanceSpecification.moiety.stereochemistry [ CodeableConcept ]; # 0..1 Stereochemistry type
    fhir:SubstanceSpecification.moiety.opticalActivity [ CodeableConcept ]; # 0..1 Optical activity type
    fhir:SubstanceSpecification.moiety.molecularFormula [ string ]; # 0..1 Molecular formula
    fhir:SubstanceSpecification.moiety.amount [ string ]; # 0..1 Quantitative value for this moiety
  ], ...;
  fhir:SubstanceSpecification.property [ # 0..* General specifications for this substance, including how it is related to other substances
    fhir:SubstanceSpecification.property.type [ CodeableConcept ]; # 0..1 Description todo
    fhir:SubstanceSpecification.property.name [ CodeableConcept ]; # 0..1 Description todo
    fhir:SubstanceSpecification.property.parameters [ string ]; # 0..1 A field that should be used to capture parameters that were used in the measurement of a property
    fhir:SubstanceSpecification.property.substanceId [ Identifier ]; # 0..1 Identifier for a substance upon which a defining property depends
    fhir:SubstanceSpecification.property.substanceName [ string ]; # 0..1 Description todo
    fhir:SubstanceSpecification.property.amount [ string ]; # 0..1 Quantitative value for this property
  ], ...;
  fhir:SubstanceSpecification.referenceInformation [ Reference(SubstanceReferenceInformation) ]; # 0..1 General information detailing this substance
  fhir:SubstanceSpecification.structure [ # 0..1 Structural information
    fhir:SubstanceSpecification.structure.stereochemistry [ CodeableConcept ]; # 0..1 Stereochemistry type
    fhir:SubstanceSpecification.structure.opticalActivity [ CodeableConcept ]; # 0..1 Optical activity type
    fhir:SubstanceSpecification.structure.molecularFormula [ string ]; # 0..1 Molecular formula
    fhir:SubstanceSpecification.structure.molecularFormulaByMoiety [ string ]; # 0..1 Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical. and each moiety separated by a dot
    fhir:SubstanceSpecification.structure.isotope [ # 0..* Applicable for single substances that contain a radionuclide or a non-natural isotopic ratio
      fhir:SubstanceSpecification.structure.isotope.nuclideId [ Identifier ]; # 0..1 Substance identifier for each non-natural or radioisotope
      fhir:SubstanceSpecification.structure.isotope.nuclideName [ CodeableConcept ]; # 0..1 Substance name for each non-natural or radioisotope
      fhir:SubstanceSpecification.structure.isotope.substitutionType [ CodeableConcept ]; # 0..1 The type of isotopic substitution present in a single substance
      fhir:SubstanceSpecification.structure.isotope.nuclideHalfLife [ Quantity ]; # 0..1 Half life - for a non-natural nuclide
      fhir:SubstanceSpecification.structure.isotope.amount [ string ]; # 0..1 Quantitative values for this isotope
      fhir:SubstanceSpecification.structure.isotope.molecularWeight [ # 0..1 The molecular weight or weight range (for proteins, polymers or nucleic acids)
        fhir:SubstanceSpecification.structure.isotope.molecularWeight.method [ CodeableConcept ]; # 0..1 The method by which the molecular weight was determined
        fhir:SubstanceSpecification.structure.isotope.molecularWeight.type [ CodeableConcept ]; # 0..1 Type of molecular weight such as exact, average (also known as. number average), weight average
        fhir:SubstanceSpecification.structure.isotope.molecularWeight.amount [ string ]; # 0..1 Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field
      ];
    ], ...;
    fhir:SubstanceSpecification.structure.molecularWeight [ See SubstanceSpecification.structure.isotope.molecularWeight ]; # 0..1 The molecular weight or weight range (for proteins, polymers or nucleic acids)
    fhir:SubstanceSpecification.structure.referenceSource [ Reference(DocumentReference) ], ... ; # 0..* Supporting literature
    fhir:SubstanceSpecification.structure.structuralRepresentation [ # 0..* Molectular structural representation
      fhir:SubstanceSpecification.structure.structuralRepresentation.type [ CodeableConcept ]; # 0..1 The type of structure (e.g. Full, Partial, Representative)
      fhir:SubstanceSpecification.structure.structuralRepresentation.representation [ string ]; # 0..1 The structural representation as text string in a format e.g. InChI, SMILES, MOLFILE, CDX
      fhir:SubstanceSpecification.structure.structuralRepresentation.attachment [ Attachment ]; # 0..1 An attached file with the structural representation
    ], ...;
  ];
  fhir:SubstanceSpecification.substanceCode [ # 0..* Codes associated with the substance
    fhir:SubstanceSpecification.substanceCode.code [ CodeableConcept ]; # 0..1 The specific code
    fhir:SubstanceSpecification.substanceCode.status [ CodeableConcept ]; # 0..1 Status of the code assignment
    fhir:SubstanceSpecification.substanceCode.statusDate [ dateTime ]; # 0..1 The date at which the code status is changed as part of the terminology maintenance
    fhir:SubstanceSpecification.substanceCode.comment [ string ]; # 0..1 Any comment can be provided in this field, if necessary
    fhir:SubstanceSpecification.substanceCode.referenceSource [ string ], ... ; # 0..* Supporting literature
  ], ...;
  fhir:SubstanceSpecification.substanceName [ # 0..* Names applicable to this substence
    fhir:SubstanceSpecification.substanceName.name [ string ]; # 0..1 The actual name
    fhir:SubstanceSpecification.substanceName.type [ CodeableConcept ]; # 0..1 Name type
    fhir:SubstanceSpecification.substanceName.language [ CodeableConcept ], ... ; # 0..* Language of the name
    fhir:SubstanceSpecification.substanceName.domain [ CodeableConcept ], ... ; # 0..* The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive
    fhir:SubstanceSpecification.substanceName.jurisdiction [ CodeableConcept ], ... ; # 0..* The jurisdiction where this name applies
    fhir:SubstanceSpecification.substanceName.officialName [ # 0..* Details of the official nature of this name
      fhir:SubstanceSpecification.substanceName.officialName.authority [ CodeableConcept ]; # 0..1 Which authority uses this official name
      fhir:SubstanceSpecification.substanceName.officialName.status [ CodeableConcept ]; # 0..1 The status of the official name
      fhir:SubstanceSpecification.substanceName.officialName.date [ dateTime ]; # 0..1 Date of official name change
    ], ...;
    fhir:SubstanceSpecification.substanceName.referenceSource [ string ], ... ; # 0..* Supporting literature
  ], ...;
  fhir:SubstanceSpecification.molecularWeight [ See SubstanceSpecification.structure.isotope.molecularWeight ], ... ; # 0..* The molecular weight or weight range (for proteins, polymers or nucleic acids)
  fhir:SubstanceSpecification.polymer [ Reference(SubstancePolymer) ]; # 0..1 Data items specific to polymers
]

Changes since R3

This resource did not exist in Release 2

This analysis is available as XML or JSON.