This page is part of the Pharmaceutical Clinical Trial Protocols (v1.0.0-ballot: STU 1 Ballot 1) based on FHIR (HL7® FHIR® Standard) v6.0.0. No current official version has been published yet. For a full list of available versions, see the Directory of published versions
Official URL: http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/protocol-amendment | Version: 1.0.0-ballot | |||
Standards status: Trial-use | Maturity Level: 1 | Computable Name: M11_ProtocolAmendment |
Amendment to a protocol. This is originally from EBM.
Context of Use
This extension may be used on the following element(s)
ResearchStudy
Usage info
Usages:
You can also check for usages in the FHIR IG Statistics
Description of Profiles, Differentials, Snapshots, and how the XML and JSON presentations work.
This structure is derived from Extension
Name | Flags | Card. | Type | Description & Constraints Filter: ![]() ![]() |
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0..* | Extension | Amendment to a protocol - from EBM | |
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1..* | Extension | Extension | |
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Content/Rules for all slices | |||
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1..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "scope" | |
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0..1 | code | Global, Not Global Binding: Study Amendment Scope Value Set (extensible) | |
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0..* | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "country" | |
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0..1 | code | Value of extension Binding: Study Amendment Country Value Set (extensible) | |
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0..* | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "region" | |
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0..1 | code | Value of extension Binding: Study Amendment Country Value Set (extensible) | |
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0..* | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "site" | |
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0..1 | Identifier | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "approvalDate" | |
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0..1 | date | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "signature" | |
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0..1 | Signature | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "signatureURL" | |
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0..1 | string | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "signatureMethod" | |
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0..1 | string | Value of extension | |
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0..3 | (Complex) | Extension URL: http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/ResearchStudyStudyAmendmentScopeImpact | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "primaryReason" | |
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0..1 | CodeableConcept | Reason for amendment, e.g. Safety Binding: Study Amendment Reason Value Set (extensible) | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "secondaryReason" | |
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0..1 | CodeableConcept | Reason for amendment, e.g. Manufacturing change Binding: Study Amendment Reason Value Set (extensible) | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "summary" | |
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0..1 | string | summary of changes | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "substantialImpactSafety" | |
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0..1 | code | Substantial impact on safety Binding: CDISC Yes No Unknown Not Applicable Value Set (required) | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "substantialImpactSafetyComment" | |
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0..1 | string | Comment on substantial impact on safety | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "substantialImpactReliability" | |
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0..1 | code | Substantial impact on reliability Binding: CDISC Yes No Unknown Not Applicable Value Set (required) | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "substantialImpactReliabilityComment" | |
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0..1 | string | Comment on substantial impact on reliability | |
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0..* | (Complex) | Extension URL: http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/protocol-amendment-detail | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "rationale" | |
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0..1 | string | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "description" | |
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0..1 | string | Value of extension | |
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1..1 | uri | "http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/protocol-amendment" | |
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0..0 | |||
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Name | Flags | Card. | Type | Description & Constraints Filter: ![]() ![]() |
---|---|---|---|---|
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0..* | Extension | Amendment to a protocol - from EBM | |
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0..1 | id | Unique id for inter-element referencing | |
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1..* | Extension | Extension Slice: Unordered, Open by value:url | |
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1..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "scope" |
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Σ | 0..1 | code | Global, Not Global Binding: Study Amendment Scope Value Set (extensible) |
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0..* | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "country" |
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Σ | 0..1 | code | Value of extension Binding: Study Amendment Country Value Set (extensible) |
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0..* | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "region" |
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Σ | 0..1 | code | Value of extension Binding: Study Amendment Country Value Set (extensible) |
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0..* | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "site" |
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Σ | 0..1 | Identifier | Value of extension |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "approvalDate" |
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Σ | 0..1 | date | Value of extension |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "signature" |
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Σ | 0..1 | Signature | Value of extension |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "signatureURL" |
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Σ | 0..1 | string | Value of extension |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "signatureMethod" |
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Σ | 0..1 | string | Value of extension |
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0..3 | (Complex) | Extension URL: http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/ResearchStudyStudyAmendmentScopeImpact | |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "primaryReason" |
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Σ | 0..1 | CodeableConcept | Reason for amendment, e.g. Safety Binding: Study Amendment Reason Value Set (extensible) |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "secondaryReason" |
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Σ | 0..1 | CodeableConcept | Reason for amendment, e.g. Manufacturing change Binding: Study Amendment Reason Value Set (extensible) |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "summary" |
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Σ | 0..1 | string | summary of changes |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "substantialImpactSafety" |
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Σ | 0..1 | code | Substantial impact on safety Binding: CDISC Yes No Unknown Not Applicable Value Set (required) |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "substantialImpactSafetyComment" |
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Σ | 0..1 | string | Comment on substantial impact on safety |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "substantialImpactReliability" |
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Σ | 0..1 | code | Substantial impact on reliability Binding: CDISC Yes No Unknown Not Applicable Value Set (required) |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "substantialImpactReliabilityComment" |
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Σ | 0..1 | string | Comment on substantial impact on reliability |
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0..* | (Complex) | Extension URL: http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/protocol-amendment-detail | |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "rationale" |
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Σ | 0..1 | string | Value of extension |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "description" |
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Σ | 0..1 | string | Value of extension |
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Σ | 1..1 | uri | "http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/protocol-amendment" |
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This structure is derived from Extension
Summary
Complex Extension: Amendment to a protocol. This is originally from EBM.
Maturity: 1
Differential View
This structure is derived from Extension
Name | Flags | Card. | Type | Description & Constraints Filter: ![]() ![]() |
---|---|---|---|---|
![]() ![]() |
0..* | Extension | Amendment to a protocol - from EBM | |
![]() ![]() ![]() |
1..* | Extension | Extension | |
![]() ![]() ![]() |
Content/Rules for all slices | |||
![]() ![]() ![]() ![]() |
1..1 | Extension | Extension | |
![]() ![]() ![]() ![]() ![]() |
0..0 | |||
![]() ![]() ![]() ![]() ![]() |
1..1 | uri | "scope" | |
![]() ![]() ![]() ![]() ![]() |
0..1 | code | Global, Not Global Binding: Study Amendment Scope Value Set (extensible) | |
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0..* | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "country" | |
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0..1 | code | Value of extension Binding: Study Amendment Country Value Set (extensible) | |
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0..* | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "region" | |
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0..1 | code | Value of extension Binding: Study Amendment Country Value Set (extensible) | |
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0..* | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "site" | |
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0..1 | Identifier | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "approvalDate" | |
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0..1 | date | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "signature" | |
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0..1 | Signature | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "signatureURL" | |
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0..1 | string | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "signatureMethod" | |
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0..1 | string | Value of extension | |
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0..3 | (Complex) | Extension URL: http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/ResearchStudyStudyAmendmentScopeImpact | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "primaryReason" | |
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0..1 | CodeableConcept | Reason for amendment, e.g. Safety Binding: Study Amendment Reason Value Set (extensible) | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "secondaryReason" | |
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0..1 | CodeableConcept | Reason for amendment, e.g. Manufacturing change Binding: Study Amendment Reason Value Set (extensible) | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "summary" | |
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0..1 | string | summary of changes | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "substantialImpactSafety" | |
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0..1 | code | Substantial impact on safety Binding: CDISC Yes No Unknown Not Applicable Value Set (required) | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "substantialImpactSafetyComment" | |
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0..1 | string | Comment on substantial impact on safety | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "substantialImpactReliability" | |
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0..1 | code | Substantial impact on reliability Binding: CDISC Yes No Unknown Not Applicable Value Set (required) | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "substantialImpactReliabilityComment" | |
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0..1 | string | Comment on substantial impact on reliability | |
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0..* | (Complex) | Extension URL: http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/protocol-amendment-detail | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "rationale" | |
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0..1 | string | Value of extension | |
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0..1 | Extension | Extension | |
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0..0 | |||
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1..1 | uri | "description" | |
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0..1 | string | Value of extension | |
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1..1 | uri | "http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/protocol-amendment" | |
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0..0 | |||
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Snapshot View
Name | Flags | Card. | Type | Description & Constraints Filter: ![]() ![]() |
---|---|---|---|---|
![]() ![]() |
0..* | Extension | Amendment to a protocol - from EBM | |
![]() ![]() ![]() |
0..1 | id | Unique id for inter-element referencing | |
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1..* | Extension | Extension Slice: Unordered, Open by value:url | |
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1..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "scope" |
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Σ | 0..1 | code | Global, Not Global Binding: Study Amendment Scope Value Set (extensible) |
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0..* | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "country" |
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Σ | 0..1 | code | Value of extension Binding: Study Amendment Country Value Set (extensible) |
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0..* | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "region" |
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Σ | 0..1 | code | Value of extension Binding: Study Amendment Country Value Set (extensible) |
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0..* | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "site" |
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Σ | 0..1 | Identifier | Value of extension |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "approvalDate" |
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Σ | 0..1 | date | Value of extension |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "signature" |
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Σ | 0..1 | Signature | Value of extension |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "signatureURL" |
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Σ | 0..1 | string | Value of extension |
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0..1 | Extension | Extension | |
![]() ![]() ![]() ![]() ![]() |
0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "signatureMethod" |
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Σ | 0..1 | string | Value of extension |
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0..3 | (Complex) | Extension URL: http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/ResearchStudyStudyAmendmentScopeImpact | |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "primaryReason" |
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Σ | 0..1 | CodeableConcept | Reason for amendment, e.g. Safety Binding: Study Amendment Reason Value Set (extensible) |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "secondaryReason" |
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Σ | 0..1 | CodeableConcept | Reason for amendment, e.g. Manufacturing change Binding: Study Amendment Reason Value Set (extensible) |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "summary" |
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Σ | 0..1 | string | summary of changes |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "substantialImpactSafety" |
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Σ | 0..1 | code | Substantial impact on safety Binding: CDISC Yes No Unknown Not Applicable Value Set (required) |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "substantialImpactSafetyComment" |
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Σ | 0..1 | string | Comment on substantial impact on safety |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "substantialImpactReliability" |
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Σ | 0..1 | code | Substantial impact on reliability Binding: CDISC Yes No Unknown Not Applicable Value Set (required) |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "substantialImpactReliabilityComment" |
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Σ | 0..1 | string | Comment on substantial impact on reliability |
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0..* | (Complex) | Extension URL: http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/protocol-amendment-detail | |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "rationale" |
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Σ | 0..1 | string | Value of extension |
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0..1 | Extension | Extension | |
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0..1 | id | Unique id for inter-element referencing | |
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0..0 | |||
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Σ | 1..1 | uri | "description" |
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Σ | 0..1 | string | Value of extension |
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Σ | 1..1 | uri | "http://hl7.org/fhir/uv/pharmaceutical-research-protocol/StructureDefinition/protocol-amendment" |
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This structure is derived from Extension
Summary
Complex Extension: Amendment to a protocol. This is originally from EBM.
Maturity: 1
Other representations of profile: CSV, Excel, Schematron
Path | Conformance | ValueSet | URI |
Extension.extension:scope.value[x] | extensible | M11AmendmentScopeVShttp://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-scope-vs From this IG | |
Extension.extension:country.value[x] | extensible | M11CountryRegionVShttp://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs From this IG | |
Extension.extension:region.value[x] | extensible | M11CountryRegionVShttp://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-country-region-vs From this IG | |
Extension.extension:primaryReason.value[x] | extensible | M11StudyAmendmentReasonVShttp://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs From this IG | |
Extension.extension:secondaryReason.value[x] | extensible | M11StudyAmendmentReasonVShttp://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/m11-study-amendment-reason-vs From this IG | |
Extension.extension:substantialImpactSafety.value[x] | required | CDISCSDTMYesNoUnknownVShttp://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs From this IG | |
Extension.extension:substantialImpactReliability.value[x] | required | CDISCSDTMYesNoUnknownVShttp://hl7.org/fhir/uv/pharmaceutical-research-protocol/ValueSet/cdisc-yes-no-vs From this IG |
Id | Grade | Path(s) | Details | Requirements |
ele-1 | error | **ALL** elements | All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count()) | |
ext-1 | error | **ALL** extensions | Must have either extensions or value[x], not both : extension.exists() != value.exists() |