Electronic Medicinal Product Information (ePI) FHIR Implementation Guide
1.0.0 - trial-use International flag

This page is part of the Electronic Medicinal Product Information (ePI) FHIR Implementation Guide (v1.0.0: STU1) based on FHIR v5.0.0. This is the current published version. For a full list of available versions, see the Directory of published versions

Resource Profile: ClinicalUseDefinitionWarningUvEpi - TTL Profile

Page standards status: Trial-use Maturity Level: 2

TTL representation of the ClinicalUseDefinition-warning-uv-epi resource profile.

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:StructureDefinition ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "ClinicalUseDefinition-warning-uv-epi"] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Minimum and Maximum # of times the the element can appear in the instance\">Card.</a></th><th style=\"width: 100px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Additional information about the element\">Description &amp; Constraints</a><span style=\"float: right\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3goXBCwdPqAP0wAAAldJREFUOMuNk0tIlFEYhp9z/vE2jHkhxXA0zJCMitrUQlq4lnSltEqCFhFG2MJFhIvIFpkEWaTQqjaWZRkp0g26URZkTpbaaOJkDqk10szoODP//7XIMUe0elcfnPd9zsfLOYplGrpRwZaqTtw3K7PtGem7Q6FoidbGgqHVy/HRb669R+56zx7eRV1L31JGxYbBtjKK93cxeqfyQHbehkZbUkK20goELEuIzEd+dHS+qz/Y8PTSif0FnGkbiwcAjHaU1+QWOptFiyCLp/LnKptpqIuXHx6rbR26kJcBX3yLgBfnd7CxwJmflpP2wUg0HIAoUUpZBmKzELGWcN8nAr6Gpu7tLU/CkwAaoKTWRSQyt89Q8w6J+oVQkKnBoblH7V0PPvUOvDYXfopE/SJmALsxnVm6LbkotrUtNowMeIrVrBcBpaMmdS0j9df7abpSuy7HWehwJdt1lhVwi/J58U5beXGAF6c3UXLycw1wdFklArBn87xdh0ZsZtArghBdAA3+OEDVubG4UEzP6x1FOWneHh2VDAHBAt80IbdXDcesNoCvs3E5AFyNSU5nbrDPZpcUEQQTFZiEVx+51fxMhhyJEAgvlriadIJZZksRuwBYMOPBbO3hePVVqgEJhFeUuFLhIPkRP6BQLIBrmMenujm/3g4zc398awIe90Zb5A1vREALqneMcYgP/xVQWlG+Ncu5vgwwlaUNx+3799rfe96u9K0JSDXcOzOTJg4B6IgmXfsygc7/Bvg9g9E58/cDVmGIBOP/zT8Bz1zqWqpbXIsd0O9hajXfL6u4BaOS6SeWAAAAAElFTkSuQmCC\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_resource.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ClinicalUseDefinition-warning-uv-epi-definitions.html#ClinicalUseDefinition\">ClinicalUseDefinition</a><a name=\"ClinicalUseDefinition\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">*</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R5/clinicalusedefinition.html\">ClinicalUseDefinition</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ClinicalUseDefinition-warning-uv-epi-definitions.html#ClinicalUseDefinition.identifier\">identifier</a><a name=\"ClinicalUseDefinition.identifier\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">*</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R5/datatypes.html#Identifier\">Identifier</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Business identifier for this clinical use.</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ClinicalUseDefinition-warning-uv-epi-definitions.html#ClinicalUseDefinition.type\">type</a><a name=\"ClinicalUseDefinition.type\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R5/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">indication | contraindication | interaction | undesirable-effect | warning</span><br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">warning</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_reference.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ClinicalUseDefinition-warning-uv-epi-definitions.html#ClinicalUseDefinition.subject\">subject</a><a name=\"ClinicalUseDefinition.subject\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">*</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R5/references.html\">Reference</a>(<a href=\"StructureDefinition-MedicinalProductDefinition-uv-epi.html\">MedicinalProductDefinition (ePI)</a>)</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">The medication, product, substance, device, procedure etc. for which this is an indication</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ClinicalUseDefinition-warning-uv-epi-definitions.html#ClinicalUseDefinition.status\">status</a><a name=\"ClinicalUseDefinition.status\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R5/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Defines whether this clinical use is draft, active or retired</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"text-decoration:line-through\">contraindication</span><a name=\"ClinicalUseDefinition.contraindication\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"text-decoration:line-through\"/><span style=\"text-decoration:line-through\">0</span><span style=\"text-decoration:line-through\">..</span><span style=\"text-decoration:line-through\">0</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"text-decoration:line-through\">indication</span><a name=\"ClinicalUseDefinition.indication\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"text-decoration:line-through\"/><span style=\"text-decoration:line-through\">0</span><span style=\"text-decoration:line-through\">..</span><span style=\"text-decoration:line-through\">0</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"text-decoration:line-through\">interaction</span><a name=\"ClinicalUseDefinition.interaction\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"text-decoration:line-through\"/><span style=\"text-decoration:line-through\">0</span><span style=\"text-decoration:line-through\">..</span><span style=\"text-decoration:line-through\">0</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <span style=\"text-decoration:line-through\">undesirableEffect</span><a name=\"ClinicalUseDefinition.undesirableEffect\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"text-decoration:line-through\"/><span style=\"text-decoration:line-through\">0</span><span style=\"text-decoration:line-through\">..</span><span style=\"text-decoration:line-through\">0</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ClinicalUseDefinition-warning-uv-epi-definitions.html#ClinicalUseDefinition.warning\">warning</a><a name=\"ClinicalUseDefinition.warning\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R5/types.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">Critical environmental, health or physical risks or hazards. For example 'Do not operate heavy machinery', 'May cause drowsiness'</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ClinicalUseDefinition-warning-uv-epi-definitions.html#ClinicalUseDefinition.warning.description\">description</a><a name=\"ClinicalUseDefinition.warning.description\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R5/datatypes.html#markdown\">markdown</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">A textual definition of this warning, with formatting.</td></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm"^^xsd:anyURI ] ;
fhir:value [ fhir:v "2"^^xsd:integer ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"^^xsd:anyURI ] ;
fhir:value [ fhir:v "trial-use" ]
  ] ) ; # 
  fhir:url [ fhir:v "http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-warning-uv-epi"^^xsd:anyURI] ; # 
  fhir:version [ fhir:v "1.0.0"] ; # 
  fhir:name [ fhir:v "ClinicalUseDefinitionWarningUvEpi"] ; # 
  fhir:title [ fhir:v "ClinicalUseDefinition Warning (ePI)"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:date [ fhir:v "2023-07-26T13:47:48+00:00"^^xsd:dateTime] ; # 
  fhir:publisher [ fhir:v "HL7 International - Biomedical Research & Regulation Work Group"] ; # 
  fhir:contact ( [
fhir:name [ fhir:v "HL7 International - Biomedical Research & Regulation Work Group" ] ;
    ( fhir:telecom [
fhir:system [ fhir:v "url" ] ;
fhir:value [ fhir:v "http://hl7.org/Special/committees/rcrim" ]     ] )
  ] ) ; # 
  fhir:description [ fhir:v "ClinicalUseDefinition Warning (ePI)"] ; # 
  fhir:jurisdiction ( [
    ( fhir:coding [
fhir:system [ fhir:v "http://unstats.un.org/unsd/methods/m49/m49.htm"^^xsd:anyURI ] ;
fhir:code [ fhir:v "001" ] ;
fhir:display [ fhir:v "World" ]     ] )
  ] ) ; # 
  fhir:fhirVersion [ fhir:v "5.0.0"] ; # 
  fhir:mapping ( [
fhir:identity [ fhir:v "workflow" ] ;
fhir:uri [ fhir:v "http://hl7.org/fhir/workflow"^^xsd:anyURI ] ;
fhir:name [ fhir:v "Workflow Pattern" ]
  ] [
fhir:identity [ fhir:v "w5" ] ;
fhir:uri [ fhir:v "http://hl7.org/fhir/fivews"^^xsd:anyURI ] ;
fhir:name [ fhir:v "FiveWs Pattern Mapping" ]
  ] [
fhir:identity [ fhir:v "idmp" ] ;
fhir:uri [ fhir:v "https://www.iso.org/obp/ui/#iso:std:iso:11615"^^xsd:anyURI ] ;
fhir:name [ fhir:v "IDMP Mapping" ]
  ] [
fhir:identity [ fhir:v "rim" ] ;
fhir:uri [ fhir:v "http://hl7.org/v3"^^xsd:anyURI ] ;
fhir:name [ fhir:v "RIM Mapping" ]
  ] ) ; # 
  fhir:kind [ fhir:v "resource"] ; # 
  fhir:abstract [ fhir:v "false"^^xsd:boolean] ; # 
  fhir:type [ fhir:v "ClinicalUseDefinition"^^xsd:anyURI] ; # 
  fhir:baseDefinition [
fhir:v "http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition>
  ] ; # 
  fhir:derivation [ fhir:v "constraint"] ; # 
  fhir:snapshot [
    ( fhir:element [
fhir:id [ fhir:v "ClinicalUseDefinition" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition" ] ;
fhir:short [ fhir:v "A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure" ] ;
fhir:definition [ fhir:v "A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:constraint [
fhir:key [ fhir:v "cud-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot be used in the same instance" ] ;
fhir:expression [ fhir:v "(ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count() + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count() + ClinicalUseDefinition.warning.count())  < 2" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition>         ]       ] [
fhir:key [ fhir:v "dom-2" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "If the resource is contained in another resource, it SHALL NOT contain nested Resources" ] ;
fhir:expression [ fhir:v "contained.contained.empty()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/DomainResource"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ] [
fhir:key [ fhir:v "dom-3" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource" ] ;
fhir:expression [ fhir:v "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/DomainResource"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ] [
fhir:key [ fhir:v "dom-4" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated" ] ;
fhir:expression [ fhir:v "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/DomainResource"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ] [
fhir:key [ fhir:v "dom-5" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "If a resource is contained in another resource, it SHALL NOT have a security label" ] ;
fhir:expression [ fhir:v "contained.meta.security.empty()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/DomainResource"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ] [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice"^^xsd:anyURI ] ;
fhir:value [ fhir:v "true"^^xsd:boolean ]         ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation"^^xsd:anyURI ] ;
fhir:value [ fhir:v "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time." ]         ] ) ;
fhir:key [ fhir:v "dom-6" ] ;
fhir:severity [ fhir:v "warning" ] ;
fhir:human [ fhir:v "A resource should have narrative for robust management" ] ;
fhir:expression [ fhir:v "text.`div`.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/DomainResource"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "Entity, Role, or Act" ]       ] [
fhir:identity [ fhir:v "workflow" ] ;
fhir:map [ fhir:v "Definition" ]       ] [
fhir:identity [ fhir:v "w5" ] ;
fhir:map [ fhir:v "clinical.general" ]       ] [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Contraindication, Therapeutic Indication, Interactions, Undesirable Effects" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.id" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.id" ] ;
fhir:short [ fhir:v "Logical id of this artifact" ] ;
fhir:definition [ fhir:v "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes." ] ;
fhir:comment [ fhir:v "Within the context of the FHIR RESTful interactions, the resource has an id except for cases like the create and conditional update. Otherwise, the use of the resouce id depends on the given use case." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Resource.id" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"^^xsd:anyURI ] ;
fhir:value [ fhir:v "id"^^xsd:anyURI ]         ] ) ;
fhir:code [ fhir:v "http://hl7.org/fhirpath/System.String"^^xsd:anyURI ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.meta" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.meta" ] ;
fhir:short [ fhir:v "Metadata about the resource" ] ;
fhir:definition [ fhir:v "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Resource.meta" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Meta"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.implicitRules" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.implicitRules" ] ;
fhir:short [ fhir:v "A set of rules under which this content was created" ] ;
fhir:definition [ fhir:v "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc." ] ;
fhir:comment [ fhir:v "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Resource.implicitRules" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "uri"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "true"^^xsd:boolean ] ;
fhir:isModifierReason [ fhir:v "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies its meaning or interpretation" ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.language" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.language" ] ;
fhir:short [ fhir:v "Language of the resource content" ] ;
fhir:definition [ fhir:v "The base language in which the resource is written." ] ;
fhir:comment [ fhir:v "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute)." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Resource.language" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "code"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Language" ]         ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding"^^xsd:anyURI ] ;
fhir:value [ fhir:v "true"^^xsd:boolean ]         ] ) ;
fhir:strength [ fhir:v "required" ] ;
fhir:description [ fhir:v "IETF language tag for a human language" ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/all-languages|5.0.0"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/all-languages|5.0.0>         ] ;
        ( fhir:additional [
fhir:purpose [ fhir:v "starter" ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/languages"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/languages>           ]         ] )       ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.text" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.text" ] ;
fhir:short [ fhir:v "Text summary of the resource, for human interpretation" ] ;
fhir:definition [ fhir:v "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety." ] ;
fhir:comment [ fhir:v "Contained resources do not have a narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later." ] ;
      ( fhir:alias [ fhir:v "narrative" ] [ fhir:v "html" ] [ fhir:v "xhtml" ] [ fhir:v "display" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "DomainResource.text" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Narrative"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "dom-6" ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "Act.text?" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contained" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contained" ] ;
fhir:short [ fhir:v "Contained, inline Resources" ] ;
fhir:definition [ fhir:v "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides context/meaning." ] ;
fhir:comment [ fhir:v "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels." ] ;
      ( fhir:alias [ fhir:v "inline resources" ] [ fhir:v "anonymous resources" ] [ fhir:v "contained resources" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "DomainResource.contained" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Resource"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "dom-2" ] [ fhir:v "dom-4" ] [ fhir:v "dom-3" ] [ fhir:v "dom-5" ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.extension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.extension" ] ;
fhir:short [ fhir:v "Additional content defined by implementations" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "DomainResource.extension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.modifierExtension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.modifierExtension" ] ;
fhir:short [ fhir:v "Extensions that cannot be ignored" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
fhir:requirements [ fhir:v "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R5/extensibility.html#modifierExtension)." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "DomainResource.modifierExtension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "true"^^xsd:boolean ] ;
fhir:isModifierReason [ fhir:v "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them" ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.identifier" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.identifier" ] ;
fhir:short [ fhir:v "Business identifier for this clinical use." ] ;
fhir:definition [ fhir:v "Business identifier for this issue." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.identifier" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Identifier"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "workflow" ] ;
fhir:map [ fhir:v "Definition.identifier" ]       ] [
fhir:identity [ fhir:v "w5" ] ;
fhir:map [ fhir:v "FiveWs.class" ]       ] [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.type" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.type" ] ;
fhir:short [ fhir:v "indication | contraindication | interaction | undesirable-effect | warning" ] ;
fhir:definition [ fhir:v "indication | contraindication | interaction | undesirable-effect | warning." ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.type" ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "code"^^xsd:anyURI ]       ] ) ;
fhir:pattern [ fhir:v "warning" ] ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "ClinicalUseDefinitionType" ]         ] ) ;
fhir:strength [ fhir:v "required" ] ;
fhir:description [ fhir:v "Overall defining type of this clinical use definition." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/clinical-use-definition-type|5.0.0"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/clinical-use-definition-type|5.0.0>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "(the type of IDMP class, out of Contraindication, Therapeutic Indication, Interactions, Undesirable Effects)" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.category" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.category" ] ;
fhir:short [ fhir:v "A categorisation of the issue, primarily for dividing warnings into subject heading areas such as \"Pregnancy\", \"Overdose\"" ] ;
fhir:definition [ fhir:v "A categorisation of the issue, primarily for dividing warnings into subject heading areas such as \"Pregnancy and Lactation\", \"Overdose\", \"Effects on Ability to Drive and Use Machines\"." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.category" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "ClinicalUseDefinitionCategory" ]         ] ) ;
fhir:strength [ fhir:v "preferred" ] ;
fhir:description [ fhir:v "A categorisation for a clinical use information item." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/clinical-use-definition-category"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/clinical-use-definition-category>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.subject" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.subject" ] ;
fhir:short [ fhir:v "The medication, product, substance, device, procedure etc. for which this is an indication" ] ;
fhir:definition [ fhir:v "The medication, product, substance, device, procedure etc. for which this is an indication." ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.subject" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Reference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/MedicinalProductDefinition-uv-epi"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/MedicinalProductDefinition-uv-epi>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "workflow" ] ;
fhir:map [ fhir:v "Definition.subject" ]       ] [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "(the link between the IDMP class and Medicinal Product)" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.status" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.status" ] ;
fhir:short [ fhir:v "Defines whether this clinical use is draft, active or retired" ] ;
fhir:definition [ fhir:v "Whether this is a current issue or one that has been retired etc." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.status" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "PublicationStatus" ]         ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding"^^xsd:anyURI ] ;
fhir:value [ fhir:v "true"^^xsd:boolean ]         ] ) ;
fhir:strength [ fhir:v "preferred" ] ;
fhir:description [ fhir:v "The lifecycle status of an artifact." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/publication-status"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/publication-status>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "workflow" ] ;
fhir:map [ fhir:v "Definition.status" ]       ] [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication" ] ;
fhir:short [ fhir:v "Specifics for when this is a contraindication" ] ;
fhir:definition [ fhir:v "Specifics for when this is a contraindication." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "0" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "BackboneElement"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "cud-1" ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Contraindication" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.id" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.id" ] ;
      ( fhir:representation [ fhir:v "xmlAttr" ] ) ;
fhir:short [ fhir:v "Unique id for inter-element referencing" ] ;
fhir:definition [ fhir:v "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Element.id" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"^^xsd:anyURI ] ;
fhir:value [ fhir:v "string"^^xsd:anyURI ]         ] ) ;
fhir:code [ fhir:v "http://hl7.org/fhirpath/System.String"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "ele-1" ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.extension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.extension" ] ;
fhir:short [ fhir:v "Additional content defined by implementations" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "Element.extension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.modifierExtension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.modifierExtension" ] ;
fhir:short [ fhir:v "Extensions that cannot be ignored even if unrecognized" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
fhir:requirements [ fhir:v "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R5/extensibility.html#modifierExtension)." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] [ fhir:v "modifiers" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "BackboneElement.modifierExtension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "true"^^xsd:boolean ] ;
fhir:isModifierReason [ fhir:v "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.diseaseSymptomProcedure" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.diseaseSymptomProcedure" ] ;
fhir:short [ fhir:v "The situation that is being documented as contraindicating against this item" ] ;
fhir:definition [ fhir:v "The situation that is being documented as contraindicating against this item." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.diseaseSymptomProcedure" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "DiseaseSymptomProcedure" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A symptom, disease or procedure." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/disease-symptom-procedure"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/disease-symptom-procedure>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Contraindication.Contraindications as \"Disease / Symptom / Procedure\" and Contraindication.Contraindications Text" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.diseaseStatus" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.diseaseStatus" ] ;
fhir:short [ fhir:v "The status of the disease or symptom for the contraindication" ] ;
fhir:definition [ fhir:v "The status of the disease or symptom for the contraindication, for example \"chronic\" or \"metastatic\"." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.diseaseStatus" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "DiseaseStatus" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "The status of a disease or symptom." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/disease-status"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/disease-status>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Contraindication.Disease Status" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.comorbidity" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.comorbidity" ] ;
fhir:short [ fhir:v "A comorbidity (concurrent condition) or coinfection" ] ;
fhir:definition [ fhir:v "A comorbidity (concurrent condition) or coinfection." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.comorbidity" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "DiseaseSymptomProcedure" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A symptom, disease or procedure." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/disease-symptom-procedure"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/disease-symptom-procedure>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Contraindication.Comorbidity" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.indication" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.indication" ] ;
fhir:short [ fhir:v "The indication which this is a contraidication for" ] ;
fhir:definition [ fhir:v "The indication which this is a contraidication for." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.indication" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Reference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "(the link from Contraindication to Therapeutic Indication)" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.applicability" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.applicability" ] ;
fhir:short [ fhir:v "An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements" ] ;
fhir:definition [ fhir:v "An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements." ] ;
fhir:comment [ fhir:v "The expression may be inlined or may be a reference to a named expression within a logic library referenced by the library element." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.applicability" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Expression"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy" ] ;
fhir:short [ fhir:v "Information about use of the product in relation to other therapies described as part of the contraindication" ] ;
fhir:definition [ fhir:v "Information about the use of the medicinal product in relation to other therapies described as part of the contraindication." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "BackboneElement"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Contraindication.Other Therapy Specifics" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.id" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.id" ] ;
      ( fhir:representation [ fhir:v "xmlAttr" ] ) ;
fhir:short [ fhir:v "Unique id for inter-element referencing" ] ;
fhir:definition [ fhir:v "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Element.id" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"^^xsd:anyURI ] ;
fhir:value [ fhir:v "string"^^xsd:anyURI ]         ] ) ;
fhir:code [ fhir:v "http://hl7.org/fhirpath/System.String"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "ele-1" ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.extension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.extension" ] ;
fhir:short [ fhir:v "Additional content defined by implementations" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "Element.extension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.modifierExtension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.modifierExtension" ] ;
fhir:short [ fhir:v "Extensions that cannot be ignored even if unrecognized" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
fhir:requirements [ fhir:v "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R5/extensibility.html#modifierExtension)." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] [ fhir:v "modifiers" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "BackboneElement.modifierExtension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "true"^^xsd:boolean ] ;
fhir:isModifierReason [ fhir:v "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.relationshipType" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.relationshipType" ] ;
fhir:short [ fhir:v "The type of relationship between the product indication/contraindication and another therapy" ] ;
fhir:definition [ fhir:v "The type of relationship between the medicinal product indication or contraindication and another therapy." ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.relationshipType" ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "TherapyRelationshipType" ]         ] ) ;
fhir:strength [ fhir:v "preferred" ] ;
fhir:description [ fhir:v "Classification of relationship between a therapy and a contraindication or an indication." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/therapy-relationship-type"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/therapy-relationship-type>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Other Therapy Specifics.Therapy Relationship Type" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.treatment" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.treatment" ] ;
fhir:short [ fhir:v "Reference to a specific medication, substance etc. as part of an indication or contraindication" ] ;
fhir:definition [ fhir:v "Reference to a specific medication (active substance, medicinal product or class of products, biological, food etc.) as part of an indication or contraindication." ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication.otherTherapy.treatment" ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/Medication"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Medication>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/Substance"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Substance>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/SubstanceDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/SubstanceDefinition>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/NutritionProduct"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/NutritionProduct>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/ActivityDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ActivityDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Therapy" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A therapy." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/therapy"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/therapy>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Other Therapy Specifics.Medication" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication" ] ;
fhir:short [ fhir:v "Specifics for when this is an indication" ] ;
fhir:definition [ fhir:v "Specifics for when this is an indication." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "0" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.indication" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "BackboneElement"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "cud-1" ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Therapeutic Indication" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.id" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.id" ] ;
      ( fhir:representation [ fhir:v "xmlAttr" ] ) ;
fhir:short [ fhir:v "Unique id for inter-element referencing" ] ;
fhir:definition [ fhir:v "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Element.id" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"^^xsd:anyURI ] ;
fhir:value [ fhir:v "string"^^xsd:anyURI ]         ] ) ;
fhir:code [ fhir:v "http://hl7.org/fhirpath/System.String"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "ele-1" ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.extension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.extension" ] ;
fhir:short [ fhir:v "Additional content defined by implementations" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "Element.extension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.modifierExtension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.modifierExtension" ] ;
fhir:short [ fhir:v "Extensions that cannot be ignored even if unrecognized" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
fhir:requirements [ fhir:v "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R5/extensibility.html#modifierExtension)." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] [ fhir:v "modifiers" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "BackboneElement.modifierExtension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "true"^^xsd:boolean ] ;
fhir:isModifierReason [ fhir:v "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.diseaseSymptomProcedure" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.diseaseSymptomProcedure" ] ;
fhir:short [ fhir:v "The situation that is being documented as an indicaton for this item" ] ;
fhir:definition [ fhir:v "The situation that is being documented as an indicaton for this item." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.indication.diseaseSymptomProcedure" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "DiseaseSymptomProcedure" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A symptom, disease or procedure." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/disease-symptom-procedure"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/disease-symptom-procedure>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Therapeutic Indication.Indication as \"Disease / Symptom / Procedure\", and Therapeutic Indication.Indication Text" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.diseaseStatus" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.diseaseStatus" ] ;
fhir:short [ fhir:v "The status of the disease or symptom for the indication" ] ;
fhir:definition [ fhir:v "The status of the disease or symptom for the indication, for example \"chronic\" or \"metastatic\"." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.indication.diseaseStatus" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "DiseaseStatus" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "The status of a disease or symptom." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/disease-status"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/disease-status>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Therapeutic Indication.Disease Status" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.comorbidity" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.comorbidity" ] ;
fhir:short [ fhir:v "A comorbidity or coinfection as part of the indication" ] ;
fhir:definition [ fhir:v "A comorbidity (concurrent condition) or coinfection as part of the indication." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.indication.comorbidity" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "DiseaseSymptomProcedure" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A symptom, disease or procedure." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/disease-symptom-procedure"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/disease-symptom-procedure>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Therapeutic Indication.Comorbidity" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.intendedEffect" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.intendedEffect" ] ;
fhir:short [ fhir:v "The intended effect, aim or strategy to be achieved" ] ;
fhir:definition [ fhir:v "The intended effect, aim or strategy to be achieved." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.indication.intendedEffect" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "ProductIntendedUse" ]         ] ) ;
fhir:strength [ fhir:v "preferred" ] ;
fhir:description [ fhir:v "The overall intended use of a product." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/product-intended-use"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/product-intended-use>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Therapeutic Indication.Intended Effect" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.duration[x]" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.duration[x]" ] ;
fhir:short [ fhir:v "Timing or duration information" ] ;
fhir:definition [ fhir:v "Timing or duration information, that may be associated with use with the indicated condition e.g. Adult patients suffering from myocardial infarction (from a few days until less than 35 days), ischaemic stroke (from 7 days until less than 6 months)." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.indication.duration[x]" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Range"^^xsd:anyURI ]       ] [
fhir:code [ fhir:v "string"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Therapeutic Indication.Timing / Duration" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.undesirableEffect" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.undesirableEffect" ] ;
fhir:short [ fhir:v "An unwanted side effect or negative outcome of the subject of this resource when being used for this indication" ] ;
fhir:definition [ fhir:v "An unwanted side effect or negative outcome that may happen if you use the drug (or other subject of this resource) for this indication." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.indication.undesirableEffect" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Reference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Therapeutic Indication.Undesirable Effects" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.applicability" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.applicability" ] ;
fhir:short [ fhir:v "An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements" ] ;
fhir:definition [ fhir:v "An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements." ] ;
fhir:comment [ fhir:v "The expression may be inlined or may be a reference to a named expression within a logic library referenced by the library element." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.indication.applicability" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Expression"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication.otherTherapy" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication.otherTherapy" ] ;
fhir:short [ fhir:v "The use of the medicinal product in relation to other therapies described as part of the indication" ] ;
fhir:definition [ fhir:v "Information about the use of the medicinal product in relation to other therapies described as part of the indication." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.indication.otherTherapy" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
fhir:contentReference [ fhir:v "http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition#ClinicalUseDefinition.contraindication.otherTherapy"^^xsd:anyURI ] ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Therapeutic Indication.Other Therapy Specifics" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction" ] ;
fhir:short [ fhir:v "Specifics for when this is an interaction" ] ;
fhir:definition [ fhir:v "Specifics for when this is an interaction." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "0" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.interaction" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "BackboneElement"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "cud-1" ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Interactions" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.id" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.id" ] ;
      ( fhir:representation [ fhir:v "xmlAttr" ] ) ;
fhir:short [ fhir:v "Unique id for inter-element referencing" ] ;
fhir:definition [ fhir:v "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Element.id" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"^^xsd:anyURI ] ;
fhir:value [ fhir:v "string"^^xsd:anyURI ]         ] ) ;
fhir:code [ fhir:v "http://hl7.org/fhirpath/System.String"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "ele-1" ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.extension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.extension" ] ;
fhir:short [ fhir:v "Additional content defined by implementations" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "Element.extension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.modifierExtension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.modifierExtension" ] ;
fhir:short [ fhir:v "Extensions that cannot be ignored even if unrecognized" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
fhir:requirements [ fhir:v "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R5/extensibility.html#modifierExtension)." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] [ fhir:v "modifiers" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "BackboneElement.modifierExtension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "true"^^xsd:boolean ] ;
fhir:isModifierReason [ fhir:v "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.interactant" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.interactant" ] ;
fhir:short [ fhir:v "The specific medication, product, food etc. or laboratory test that interacts" ] ;
fhir:definition [ fhir:v "The specific medication, product, food, substance etc. or laboratory test that interacts." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.interactant" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "BackboneElement"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Interactions.Interactant and Interactions.Interactions Text" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.interactant.id" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.interactant.id" ] ;
      ( fhir:representation [ fhir:v "xmlAttr" ] ) ;
fhir:short [ fhir:v "Unique id for inter-element referencing" ] ;
fhir:definition [ fhir:v "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Element.id" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"^^xsd:anyURI ] ;
fhir:value [ fhir:v "string"^^xsd:anyURI ]         ] ) ;
fhir:code [ fhir:v "http://hl7.org/fhirpath/System.String"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "ele-1" ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.interactant.extension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.interactant.extension" ] ;
fhir:short [ fhir:v "Additional content defined by implementations" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "Element.extension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.interactant.modifierExtension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.interactant.modifierExtension" ] ;
fhir:short [ fhir:v "Extensions that cannot be ignored even if unrecognized" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
fhir:requirements [ fhir:v "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R5/extensibility.html#modifierExtension)." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] [ fhir:v "modifiers" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "BackboneElement.modifierExtension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "true"^^xsd:boolean ] ;
fhir:isModifierReason [ fhir:v "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.interactant.item[x]" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.interactant.item[x]" ] ;
fhir:short [ fhir:v "The specific medication, product, food etc. or laboratory test that interacts" ] ;
fhir:definition [ fhir:v "The specific medication, product, food, substance etc. or laboratory test that interacts." ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.interactant.item[x]" ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Reference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/Medication"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Medication>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/Substance"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Substance>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/NutritionProduct"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/NutritionProduct>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct>         ] [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Interactant" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "An interactant - a substance that may have a clinically significant effect on another." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/interactant"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/interactant>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Interactions.Interactant and Interactions.Interactions Text" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.type" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.type" ] ;
fhir:short [ fhir:v "The type of the interaction e.g. drug-drug interaction, drug-lab test interaction" ] ;
fhir:definition [ fhir:v "The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.type" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "InteractionType" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A categorisation for an interaction between two substances." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/interaction-type"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/interaction-type>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Interactions.Interactions Type" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.effect" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.effect" ] ;
fhir:short [ fhir:v "The effect of the interaction, for example \"reduced gastric absorption of primary medication\"" ] ;
fhir:definition [ fhir:v "The effect of the interaction, for example \"reduced gastric absorption of primary medication\"." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.effect" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "InteractionEffect" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A interaction effect of clinical use of a medication or other substance." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/interaction-effect"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/interaction-effect>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Interactions.Interactions Effect" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.incidence" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.incidence" ] ;
fhir:short [ fhir:v "The incidence of the interaction, e.g. theoretical, observed" ] ;
fhir:definition [ fhir:v "The incidence of the interaction, e.g. theoretical, observed." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.incidence" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "UndesirableEffectSymptom" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A categorisation for incidence of occurence of an interaction." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/interaction-incidence"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/interaction-incidence>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Interactions.Interactions Incidence" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction.management" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.management" ] ;
fhir:short [ fhir:v "Actions for managing the interaction" ] ;
fhir:definition [ fhir:v "Actions for managing the interaction." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.interaction.management" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "InteractionManagement" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A type of management for an interaction of a medication or other substance." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/interaction-management"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/interaction-management>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Interactions.Management Actions" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.population" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.population" ] ;
fhir:short [ fhir:v "The population group to which this applies" ] ;
fhir:definition [ fhir:v "The population group to which this applies." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.population" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Reference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/Group"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Group>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Population Specifics" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.library" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.library" ] ;
fhir:short [ fhir:v "Logic used by the clinical use definition" ] ;
fhir:definition [ fhir:v "Logic used by the clinical use definition." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.library" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "canonical"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/Library"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Library>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.undesirableEffect" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect" ] ;
fhir:short [ fhir:v "A possible negative outcome from the use of this treatment" ] ;
fhir:definition [ fhir:v "Describe the possible undesirable effects (negative outcomes) from the use of the medicinal product as treatment." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "0" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "BackboneElement"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "cud-1" ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Undesirable Effects" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.undesirableEffect.id" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect.id" ] ;
      ( fhir:representation [ fhir:v "xmlAttr" ] ) ;
fhir:short [ fhir:v "Unique id for inter-element referencing" ] ;
fhir:definition [ fhir:v "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Element.id" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"^^xsd:anyURI ] ;
fhir:value [ fhir:v "string"^^xsd:anyURI ]         ] ) ;
fhir:code [ fhir:v "http://hl7.org/fhirpath/System.String"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "ele-1" ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.undesirableEffect.extension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect.extension" ] ;
fhir:short [ fhir:v "Additional content defined by implementations" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "Element.extension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.undesirableEffect.modifierExtension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect.modifierExtension" ] ;
fhir:short [ fhir:v "Extensions that cannot be ignored even if unrecognized" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
fhir:requirements [ fhir:v "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R5/extensibility.html#modifierExtension)." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] [ fhir:v "modifiers" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "BackboneElement.modifierExtension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "true"^^xsd:boolean ] ;
fhir:isModifierReason [ fhir:v "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.undesirableEffect.symptomConditionEffect" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect.symptomConditionEffect" ] ;
fhir:short [ fhir:v "The situation in which the undesirable effect may manifest" ] ;
fhir:definition [ fhir:v "The situation in which the undesirable effect may manifest." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect.symptomConditionEffect" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableReference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/StructureDefinition/ObservationDefinition"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/ObservationDefinition>         ] )       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "UndesirableEffectSymptom" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "An undesirable effect of clinical use." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/undesirable-effect-symptom"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/undesirable-effect-symptom>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Undesirable Effects.Undesirable Effect as \"Symptom / Condition / Effect\"" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.undesirableEffect.classification" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect.classification" ] ;
fhir:short [ fhir:v "High level classification of the effect" ] ;
fhir:definition [ fhir:v "High level classification of the effect." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect.classification" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "UndesirableEffectClassification" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A categorisation for an undesirable effect." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/undesirable-effect-classification"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/undesirable-effect-classification>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Undesirable Effects.Symptom / Condition / Effect Classification" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence" ] ;
fhir:short [ fhir:v "How often the effect is seen" ] ;
fhir:definition [ fhir:v "How often the effect is seen." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "UndesirablEffectFrequency" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "A categorisation for a frequency of occurence of an undesirable effect." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/undesirable-effect-frequency"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/undesirable-effect-frequency>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "Undesirable Effects.Frequency of Occurrence" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.warning" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.warning" ] ;
fhir:short [ fhir:v "Critical environmental, health or physical risks or hazards. For example 'Do not operate heavy machinery', 'May cause drowsiness'" ] ;
fhir:definition [ fhir:v "A critical piece of information about environmental, health or physical risks or hazards that serve as caution to the user. For example 'Do not operate heavy machinery', 'May cause drowsiness', or 'Get medical advice/attention if you feel unwell'." ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.warning" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "BackboneElement"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "cud-1" ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.warning.id" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.warning.id" ] ;
      ( fhir:representation [ fhir:v "xmlAttr" ] ) ;
fhir:short [ fhir:v "Unique id for inter-element referencing" ] ;
fhir:definition [ fhir:v "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "Element.id" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"^^xsd:anyURI ] ;
fhir:value [ fhir:v "string"^^xsd:anyURI ]         ] ) ;
fhir:code [ fhir:v "http://hl7.org/fhirpath/System.String"^^xsd:anyURI ]       ] ) ;
      ( fhir:condition [ fhir:v "ele-1" ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.warning.extension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.warning.extension" ] ;
fhir:short [ fhir:v "Additional content defined by implementations" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "Element.extension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "false"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.warning.modifierExtension" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.warning.modifierExtension" ] ;
fhir:short [ fhir:v "Extensions that cannot be ignored even if unrecognized" ] ;
fhir:definition [ fhir:v "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ] ;
fhir:comment [ fhir:v "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ] ;
fhir:requirements [ fhir:v "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R5/extensibility.html#modifierExtension)." ] ;
      ( fhir:alias [ fhir:v "extensions" ] [ fhir:v "user content" ] [ fhir:v "modifiers" ] ) ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ] ;
fhir:base [
fhir:path [ fhir:v "BackboneElement.modifierExtension" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "*" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "Extension"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] [
fhir:key [ fhir:v "ext-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "Must have either extensions or value[x], not both" ] ;
fhir:expression [ fhir:v "extension.exists() != value.exists()" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Extension"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ] ) ;
fhir:isModifier [ fhir:v "true"^^xsd:boolean ] ;
fhir:isModifierReason [ fhir:v "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "rim" ] ;
fhir:map [ fhir:v "N/A" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.warning.description" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.warning.description" ] ;
fhir:short [ fhir:v "A textual definition of this warning, with formatting." ] ;
fhir:definition [ fhir:v "A textual definition of this warning, with formatting." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.warning.description" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "markdown"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.warning.code" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.warning.code" ] ;
fhir:short [ fhir:v "A coded or unformatted textual definition of this warning" ] ;
fhir:definition [ fhir:v "A coded or unformatted textual definition of this warning." ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ] ;
fhir:base [
fhir:path [ fhir:v "ClinicalUseDefinition.warning.code" ] ;
fhir:min [ fhir:v "0"^^xsd:nonNegativeInteger ] ;
fhir:max [ fhir:v "1" ]       ] ;
      ( fhir:type [
fhir:code [ fhir:v "CodeableConcept"^^xsd:anyURI ]       ] ) ;
      ( fhir:constraint [
fhir:key [ fhir:v "ele-1" ] ;
fhir:severity [ fhir:v "error" ] ;
fhir:human [ fhir:v "All FHIR elements must have a @value or children" ] ;
fhir:expression [ fhir:v "hasValue() or (children().count() > id.count())" ] ;
fhir:source [
fhir:v "http://hl7.org/fhir/StructureDefinition/Element"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ] ) ;
fhir:mustSupport [ fhir:v "false"^^xsd:boolean ] ;
fhir:isModifier [ fhir:v "false"^^xsd:boolean ] ;
fhir:isSummary [ fhir:v "true"^^xsd:boolean ] ;
fhir:binding [
        ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"^^xsd:anyURI ] ;
fhir:value [ fhir:v "WarningType" ]         ] ) ;
fhir:strength [ fhir:v "example" ] ;
fhir:description [ fhir:v "Classification of warning type." ] ;
fhir:valueSet [
fhir:v "http://hl7.org/fhir/ValueSet/warning-type"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/ValueSet/warning-type>         ]       ] ;
      ( fhir:mapping [
fhir:identity [ fhir:v "idmp" ] ;
fhir:map [ fhir:v "n/a" ]       ] )     ] )
  ] ; # 
  fhir:differential [
    ( fhir:element [
fhir:id [ fhir:v "ClinicalUseDefinition" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition" ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.identifier" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.identifier" ] ;
fhir:short [ fhir:v "Business identifier for this clinical use." ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.type" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.type" ] ;
fhir:pattern [ fhir:v "warning" ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.subject" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.subject" ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ] ;
      ( fhir:type [
fhir:code [ fhir:v "Reference"^^xsd:anyURI ] ;
        ( fhir:targetProfile [
fhir:v "http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/MedicinalProductDefinition-uv-epi"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/MedicinalProductDefinition-uv-epi>         ] )       ] )     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.status" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.status" ] ;
fhir:short [ fhir:v "Defines whether this clinical use is draft, active or retired" ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.contraindication" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.contraindication" ] ;
fhir:max [ fhir:v "0" ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.indication" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.indication" ] ;
fhir:max [ fhir:v "0" ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.interaction" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.interaction" ] ;
fhir:max [ fhir:v "0" ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.undesirableEffect" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.undesirableEffect" ] ;
fhir:max [ fhir:v "0" ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.warning" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.warning" ] ;
fhir:min [ fhir:v "1"^^xsd:nonNegativeInteger ]     ] [
fhir:id [ fhir:v "ClinicalUseDefinition.warning.description" ] ;
fhir:path [ fhir:v "ClinicalUseDefinition.warning.description" ] ;
fhir:short [ fhir:v "A textual definition of this warning, with formatting." ]     ] )
  ] . #