HL7.FHIR.UV.CDISC-MAPPING\Concomitant Medications

This page is part of the CDISC Mapping FHIR IG (v0.1.0: STU 1 Ballot 1) based on FHIR R4. The current version which supercedes this version is 1.0.0. For a full list of available versions, see the Directory of published versions

Concomitant Medications

The fact a patient is taking or has been exposed to a medication can be expressed in a number of ways in FHIR, with some conveying a greater degree of certainty and/or detail about exactly what was taken and when. Mappings are provided for all of these resources.

MedicationStatement - captures information about a drug that the patient is believed to be taking. This is generally 'summary' information and may span multiple orders. It can also be used for non-prescribed medications. In some cases, it will also assert medications not taken.
MedicationRequest - captures drug orders and prescriptions (though it can also contain recommendations and plans). Not all ordered drugs are actually taken (or taken as ordered)
MedicationDispense - captures information about a drug that was supplied to or for a patient. It also conveys the instructions for administering the supplied medication. The existence of a dispense gives confidence that the medication was actually received, but again, not dispensed are actually taken (or taken according to instructions)
MedicationAdministration - captures information about a specific administration of a particular drug at a specific time. These records generally only exist for in-patient administrations, though in principle they could be captured for community administrations, either by a healthcare professional or even by the patient themselves. These records are highly specific and are the most likely to reflect what the patient actually received.
Immunization - captures information about a specific administration of a vaccine. Like MedicationAdministration, these records are highly specific and are the most likely to reflect what the patient actually received.

Note that the same resources are used when dealing with study drugs as with concomitant drugs, so when converting data from FHIR, data will need to be filtered to differentiate between the two.

CM Mappings

Guidance on interpreting the table can be found here.

CDISC	FHIR map (or gap)	Comment
Study Identifier	STUDYID	STUDYID	ResearchStudy.identifier	ResearchSubject.where(subject=(MedicationStatement.subject\|MedicationRequest.subject\|MedicationDispense.subject\|MedicationAdministration.subject\|Immunizations.patient)).study.resolve().partOf.resolve().identifier.value MedicationStatement.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value MedicationRequest.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value MedicationDispense.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value MedicationAdministration.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value Immunization.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value	Mapping is based on presumption that research subject will be tied to site-specific ResearchStudy, which will then be part of overall ResearchStudy. The path using the extension will only exist if the system maintaining the MedicationStatement/Request/Dispense/Administration or Immunization is aware of its relevance to the Study.
Study Site Identifier	SITEID	DM.SITEID	ResearchStudy.site	ResearchSubject.where(subject=(MedicationStatement.subject\|MedicationRequest.subject\|MedicationDispense.subject\|MedicationAdministration.subject\|Immunizations.patient)).study.resolve().identifier.value MedicationStatement.extension(workflow-researchstudy).valueReference.resolve().identifier.value MedicationRequest.extension(workflow-researchstudy).valueReference.resolve().identifier.value MedicationDispense.extension(workflow-researchstudy).valueReference.resolve().identifier.value MedicationAdministration.extension(workflow-researchstudy).valueReference.resolve().identifier.value Immunization.extension(workflow-researchstudy).valueReference.resolve().identifier.value	Mapping is based on presumption that research subject will be tied to site-specific ResearchStudy, which will then be part of overall ResearchStudy. The path using the extension will only exist if the system maintaining the MedicationStatement/Request/Dispense/Administration or Immunization is aware of its relevance to the Study.
Subject Identifier for the Study	SUBJID	DM.SUBJID	ResearchSubject.identifier	ResearchSubject.where(individual=(MedicationStatement.subject\|MedicationRequest.subject\|MedicationDispense.subject\|MedicationAdministration.subject\|Immunizations.patient).identifier.value	Study subject is found by finding the StudySubject that corresponds to the same Patient and ResearchStudy as the focal resource. No standard way to decide which subject identifier to use
Category for Medication	CMCAT	CMCAT	MedicationStatement.category	MedicationStatement.category	In FHIR, an medication can be categorized in multiple ways and to the granularity desired. When converting from FHIR to CDASH, systems will need to look at the FHIR categories (and potentially other information) to determine how best to populate CMCAT and CMSCAT based on the study-designed categories (unless they've pre-arranged with the EHR to ensure it captures the same codes)
MedicationRequest.category	MedicationRequest.category
MedicationDispense.category	MedicationDispense.category
MedicationAdministration.category	MedicationAdministration.category
Subcategory for Medication	CMSCAT	CMSCAT	MedicationStatement.category	MedicationStatement.category	In FHIR, an medication can be categorized in multiple ways and to the granularity desired. When converting from FHIR to CDASH, systems will need to look at the FHIR categories (and potentially other information) to determine how best to populate CMCAT and CMSCAT based on the study-designed categories (unless they've pre-arranged with the EHR to ensure it captures the same codes)
MedicationRequest.category	MedicationRequest.category
MedicationDispense.category	MedicationDispense.category
MedicationAdministration.category	MedicationAdministration.category
Any Concomitant Medications Taken	CMYN		This would be determined by dates within the protocol. What constitutes a 'concomitant' drug is study-specific and would need to be evaluated on a study level. FHIR would not normally store that information. However an extension on ResearchSubject could be utilized or could be captured in a Questionnaire.
CM Sponsor-Defined Identifier	CMSPID	CMSPID	MedicationStatement.identifier	MedicationStatement.identifier
MedicationRequest.identifier	MedicationRequest.identifier
MedicationDispense.identifier	MedicationDispense.identifier
MedicationAdministration.identifier	MedicationAdministration.identifier
Immunization.identifier	Immunization.identifier
Reported Name of Drug, Med, or Therapy	CMTRT	CMTRT	MedicationStatement.medicationCodeableconcept	MedicationStatement.medication.medicationCodeableConcept
MedicationStatement.medicationReference	MedicationStatement.medication.medicationReference.resolve().code
MedicationRequest.medicationCodeableConcept	MedicationRequest.medication.medicationCodeableConcept
MedicationRequest.medicationReference	MedicationRequest.medication.medicationReference.resolve().code
MedicationDispense.medicationCodeableConcept	MedicationDispense.medication.medicationCodeableConcept
MedicationDispense.medicationReference	MedicationDispense.medication.medicationReference.resolve().code
MedicationAdministration.medicationCodeableConcept	MedicationAdministration.medication.medicationCodeableConcept
MedicationAdministration.medicationReference	MedicationAdministration.medication.medicationReference.resolve().code
Immunization.vaccineCode	Immunization.vaccineCode
CM Pre-Specified	CMPRESP	CMPRESP	Would not expect to receive from the site.
CM Occurrence	CMOCCUR	CMOCCUR	MedicationStatement.status	MedicationStatement.status	In general, medication records won't exist unless the patient is taking the medication, though there is an ability to say a medication isn't currently being taken or shouldn't be taken
MedicationRequest.doNotPerform	MedicationRequest.doNotPerform=true
MedicationRequest.status	MedicationRequest.status IN {'entered-in-error'\|'cancelled'\|'stopped'}
MedicationDispense.status	MedicationRequest.status IN {entered-in-error'\|'cancelled'\|'stopped'}
MedicationAdministration.status	MedicationAdministration.status
Immunization.status	Immunization.status IN {'completed'\|'entered-in-error'}
Concomitant Meds Active Ingredients	CMINGRD		Medication.ingredient	MedicationStatement.medicationReference.resolve().ingredient.where(isActive)
Medication.ingredient	MedicationRequest.medicationReference.resolve().ingredient.where(isActive)
Medication.ingredient	MedicationDispense.medicationReference.resolve().ingredient.where(isActive)
Medication.ingredient	MedicationAdministration.medicationReference.resolve().ingredient.where(isActive)
Immunization.ingredient	Immunization.medicationReference.resolve().ingredient.where(isActive)
CM Indication	CMINDC	CMINDC	MedicationStatement.reasonCode	MedicationStatement.reasonCode
MedicationRequest.reasonCode	MedicationRequest.reasonCode
MedicationAdministration.reasonCode	MedicationAdministration.reasonCode
Immunization.reasonCode	Immunization.reasonCode
Related AdverseEvent ID	CMAENO		AdverseEvent.identifier	AdverseEvent.where(suspectEntity.instanceReference=MedicationX).identifier	This could match on AdverseEvent by code. (Note that the AdverseEvent points to the medication record, not the reverse
Related Medical History Event ID	CMMHNO		Condition.identifier	MedicationStatement.reasonReference.resolve().identifier
Condition.identifier	MedicationRequest.reasonReference.resolve().identifier
Condition.identifier	MedicationAdministration.reasonReference.resolve().identifier
Immunization.identifier	Immunization.reasonReference.resolve().identifier
CM Dose per Administration	CMDOSE	CMDOSE	MedicationStatement.dosage	MedicationStatement.dosage.doseAndRate.doseQuantity
MedicationRequest.dosageInstruction	MedicationRequest.dosageInstruction.doseAndRate.doseQuantity
MedicationDispense.dosageInstruction	MedicationDispense.dosageInstruction.doseAndRate.doseQuantity
MedicationAdministration.dosage.dose	MedicationAdministration.dosage.dose
Immunization.doesQuantity	Immunization.doseQuantity
Concomitant Meds Dose Description	CMDSTXT	CMDOSTXT; CMDOSE	MedicationStatement.dosage	MedicationStatement.dosage.text	Requires combining multiple repetitions together
MedicationRequest.dosageInstruction	MedicationRequest.dosageInstruction.text
MedicationDispense.dosageInstruction	MedicationDispense.dosageInstruction.text
MedicationAdministration.dosage.text	MedicationAdministration.dosage.text
CM Total Daily Dose	CMDOSTOT	CMDOSTOT	MedicationStatement.dosage.maxDosePerPeriod	MedicationStatement.dosage.maxDosePerPeriod	If Total Daily Dose is required by the sponsor, it may require collection of the drug dose and frequency to derive the CM Total Daily Dose.
MedicationRequest.dosage.maxDosePerPeriod	MedicationRequest.dosageInstruction.dosage.maxDosePerPeriod
MedicationDispense.dosage.maxDosePerPeriod	MedicationDispense.dosageInstruction.dosage.maxDosePerPeriod
Immunization.doseQuantity	Immunization.doseQuantity
CM Dose Units	CMDOSU	CMDOSU	MedicationStatement.dosage.maxDosePerPeriod	MedicationStatement.dosage.maxDosePerPeriod.code
MedicationRequest.dosage.maxDosePerPeriod	MedicationRequest.dosage.maxDosePerPeriod.code
MedicationDispense.dosage.maxDosePerPeriod	MedicationDispense.dosage.maxDosePerPeriod.code
CM Dose Form	CMDOSFRM	CMDOSFRM	Medication.form	MedicationStatement.medicationReference.resolve().form
Medication.form	MedicationRequest.medicationReference.resolve().form
Medication.form	MedicationDispense.medicationReference.resolve().form
CM Dosing Frequency per Interval	CMDOSFRQ	CMDOSFRQ	MedicationStatement.dosage	MedicationStatement.dosage.timing.frequency
MedicationRequest.dosageInstruction	MedicationRequest.dosageInstruction.timing.frequencey
MedicationDispense.dosageInstruction	MedicationDispense.dosageInstruction.timing.frequency
CM Route of Administration	CMROUTE	CMROUTE	MedicationStatement.dosage	MedicationStatement.dosage.route
MedicationRequest.dosageInstruction	MedicationRequest.dosageInstruction.route
MedicationDispense.dosageInstruction	MedicationDispense.dosageInstruction.route
MedicationAdministration.dosage.route	MedicationAdministration.dosage.route
Immunization.route	Immunization.route
Concomitant Meds Start Date	CMSTDTC	CMSTDTC	MedicationStatement.effectiveDateTime	MedicationStatement.effectiveDateTime	start includes both date and time, though time commonly won't be specified
MedicationStatement.effectivePeriod	MedicationStatement.effectivePeriod.start
MedicationRequest.dosageInstruction.timing	MedicationRequest.dosageInstruction.timing.repeat.boundsPeriod.start
MedicationDispense.dosageInstruction.timing	MedicationDispense.dosageInstruction.timing.repeat.boundsPeriod.start
Immunization.occurrenceDateTime	Immunization.occurrence.occurrenceDateTime
Immunization.occurrenceString	Immunization.occurrence.orrurrenceString
Concomitant Meds Start Time	CMSTDTC	CMSTDTC	MedicationStatement.effectiveDateTime	MedicationStatement.effectiveDateTime	start includes both date and time, though time commonly won't be specified
MedicationStatement.effectivePeriod	MedicationStatement.effectivePeriod.start
MedicationRequest.dosageInstruction	MedicationRequest.dosageInstruction.timing.repeat.boundsPeriod.start
MedicationDispense.dosage.instruction	MedicationDispense.dosageInstruction.timing.repeat.boundsPeriod.start
Immunization.occurrenceDateTime	Immunization.occurrence.occurrenceDateTime
Immunization.occurrenceString	Immunization.occurrence.orrurrenceString
Concomitant Meds End Date	CMSTDTC	CMSTDTC	MedicationStatement.effectiveDateTime	MedicationStatement.effectiveDateTime	end includes both date and time, though time commonly won't be specified
MedicationStatement.effectivePeriod	MedicationStatement.effectivePeriod.end
MedicationRequest.dosageInstruction	MedicationRequest.dosageInstruction.timing.repeat.boundsPeriod.end
MedicationDispense.dosage.instruction	MedicationDispense.dosageInstruction.timing.repeat.boundsPeriod.end
Immunization.occurrence	Immunization.occurrence.occurrenceDateTime Immunization.occurrence.orrurrenceString
Concomitant Meds End Time	CMENDTC	CMENDTC	MedicationStatement.effectiveDateTime	MedicationStatement.effectiveDateTime	end includes both date and time, though time commonly won't be specified
MedicationStatement.effectivePeriod	MedicationStatement.effectivePeriod.end
MedicationRequest.dosageInstruction	MedicationRequest.dosageInstruction.timing.repeat.boundsPeriod.end
MedicationDispense.dosageInstruction	MedicationDispense.dosageInstruction.timing.repeat.boundsPeriod.end
Immunization.occurrence	Immunization.occurrence.occurrenceDateTime Immunization.occurrence.orrurrenceString
Prior Concomitant Medications	CMPRIOR	CMSTRF; CMSTRTPT	This would need to be an extension added to the study extension on the medication resource - normally it is not captured except in the context of a study (and would be a study-specific assertion)
Ongoing Concomitant Medications	CMONGO	CMENRF; CMENRTPT	This would need to be an extension added to the study extension on the medication resource - normally it is not captured except in the context of a study (and would be a study-specific assertion)
Standardized Medication Name	CMDECOD	CMDECOD	MedicationStatement.medicationCodeableConcept	MedicationStatement.medicationCodeableConcept MedicationStatement.medicationReference.resolve().code	We would not expect to receive these from the site.
Medication.code	MedicationStatement.medicationCodeableConcept MedicationStatement.medicationReference.resolve().code
MedicationRequest.medicationCodeableConcept	MedicationRequest.medicationCodeableConcept MedicationRequest.medicationReference.resolve().code
Medication.code	MedicationRequest.medicationCodeableConcept MedicationRequest.medicationReference.resolve().code
MedicationDispense.medicationCodeableConcept	MedicationDispense.medicationCodeableConcept MedicationDispense.medicationReference.resolve().code
Medication.code	MedicationDispense.medicationCodeableConcept MedicationDispense.medicationReference.resolve().code
MedicationAdministration.medicationCodeableConcept	MedicationAdministration.medicationCodeableConcept MedicationAdministration.medicationReference.resolve().code
Medication.code	MedicationAdministration.medicationCodeableConcept MedicationAdministration.medicationReference.resolve().code
Immunization.vaccineCode	Immunization.vaccineCode
CM Medication Class	CMCLAS	CMCLAS	MedicationStatement.medicationCodeableConcept	MedicationStatement.medicationCodeableConcept MedicationStatement.medicationReference.resolve().code	These can be provided as alternate codings, however typically encoding is performed by the sponsor and we would not expect to receive these from the site.
Medication.code	MedicationStatement.medicationCodeableConcept MedicationStatement.medicationReference.resolve().code
MedicationRequest.medicationCodeableConcept	MedicationRequest.medicationCodeableConcept MedicationRequest.medicationReference.resolve().code
Medication.code	MedicationRequest.medicationCodeableConcept MedicationRequest.medicationReference.resolve().code
MedicationDispense.medicationCodeableConcept	MedicationDispense.medicationCodeableConcept MedicationDispense.medicationReference.resolve().code
Medication.code	MedicationDispense.medicationCodeableConcept MedicationDispense.medicationReference.resolve().code
MedicationAdministration.medicationCodeableConcept	MedicationAdministration.medicationCodeableConcept MedicationAdministration.medicationReference.resolve().code
Medication.code	MedicationAdministration.medicationCodeableConcept MedicationAdministration.medicationReference.resolve().code
Immunizations.vaccineCode	Immunization.vaccineCode
CM Medication Class Code	CMCLASCD	CMCLASCD	MedicationStatement.medicationCodeableConcept	MedicationStatement.medicationCodeableConcept MedicationStatement.medicationReference.resolve().code	These can be provided as alternate codings, however typically encoding is performed by the sponsor and we would not expect to receive these from the site.
Medication.code	MedicationStatement.medicationCodeableConcept MedicationStatement.medicationReference.resolve().code
MedicationRequest.medicationCodeableConcept	MedicationRequest.medicationCodeableConcept MedicationRequest.medicationReference.resolve().code
Medication.code	MedicationRequest.medicationCodeableConcept MedicationRequest.medicationReference.resolve().code
MedicationDispense.medicationCodeableConcept	MedicationDispense.medicationCodeableConcept MedicationDispense.medicationReference.resolve().code
Medication.code	MedicationDispense.medicationCodeableConcept MedicationDispense.medicationReference.resolve().code
MedicationAdministration.medicationCodeableConcept	MedicationAdministration.medicationCodeableConcept MedicationAdministration.medicationReference.resolve().code
Medication.code	MedicationAdministration.medicationCodeableConcept MedicationAdministration.medicationReference.resolve().code
Immunization.vaccineCode	Immunization.vaccineCode
ATC Level 1 Description	CMATC1	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site.
ATC Level 1 Code	CMATC1CD	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site. All coding levels are found in the same attribute as distinct codings. The granularity is distinguished by the code system or knowledge of the code
ATC Level 2 Description	CMATC2	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site.
ATC Level 2 Code	CMATC2CD	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site. All coding levels are found in the same attribute as distinct codings. The granularity is distinguished by the code system or knowledge of the code
ATC Level 3 Description	CMATC3	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site.
ATC Level 3 Code	CMATC3CD	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site. All coding levels are found in the same attribute as distinct codings. The granularity is distinguished by the code system or knowledge of the code
ATC Level 4 Description	CMATC4	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site.
ATC Level 4 Code	CMATC4CD	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site. All coding levels are found in the same attribute as distinct codings. The granularity is distinguished by the code system or knowledge of the code
ATC Level 5 Description	CMATC5	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site.
ATC Level 5 Code	CMATC5CD	SUPPCM.QVAL	Encoding is performed by the sponsor and we would not expect to receive these from the site. All coding levels are found in the same attribute as distinct codings. The granularity is distinguished by the code system or knowledge of the code

CDISC

FHIR map (or gap)

Comment

Name

CDASH

SDTM

Element

FHIRPath

Study Identifier

STUDYID

ResearchStudy.identifier

ResearchSubject.where(subject=(MedicationStatement.subject|MedicationRequest.subject|MedicationDispense.subject|MedicationAdministration.subject|Immunizations.patient)).study.resolve().partOf.resolve().identifier.value

MedicationStatement.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value

MedicationRequest.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value

MedicationDispense.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value

MedicationAdministration.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value

Immunization.extension(workflow-researchstudy).valueReference.resolve().partOf.resolve().identifier.value

Mapping is based on presumption that research subject will be tied to site-specific ResearchStudy, which will then be part of overall ResearchStudy.

The path using the extension will only exist if the system maintaining the MedicationStatement/Request/Dispense/Administration or Immunization is aware of its relevance to the Study.

Study Site Identifier

SITEID

DM.SITEID

ResearchStudy.site

MedicationStatement.extension(workflow-researchstudy).valueReference.resolve().identifier.value

MedicationRequest.extension(workflow-researchstudy).valueReference.resolve().identifier.value

MedicationDispense.extension(workflow-researchstudy).valueReference.resolve().identifier.value

MedicationAdministration.extension(workflow-researchstudy).valueReference.resolve().identifier.value

Immunization.extension(workflow-researchstudy).valueReference.resolve().identifier.value

Subject Identifier for the Study

SUBJID

DM.SUBJID

ResearchSubject.identifier

ResearchSubject.where(individual=(MedicationStatement.subject|MedicationRequest.subject|MedicationDispense.subject|MedicationAdministration.subject|Immunizations.patient).identifier.value

Study subject is found by finding the StudySubject that corresponds to the same Patient and ResearchStudy as the focal resource.

No standard way to decide which subject identifier to use

Category for Medication

CMCAT

MedicationStatement.category

In FHIR, an medication can be categorized in multiple ways and to the granularity desired. When converting from FHIR to CDASH, systems will need to look at the FHIR categories (and potentially other information) to determine how best to populate CMCAT and CMSCAT based on the study-designed categories (unless they've pre-arranged with the EHR to ensure it captures the same codes)

MedicationRequest.category

MedicationDispense.category

MedicationAdministration.category

Subcategory for Medication

CMSCAT

MedicationStatement.category

MedicationRequest.category

MedicationDispense.category

MedicationAdministration.category

Any Concomitant Medications Taken

CMYN

This would be determined by dates within the protocol.

What constitutes a 'concomitant' drug is study-specific and would need to be evaluated on a study level. FHIR would not normally store that information. However an extension on ResearchSubject could be utilized or could be captured in a Questionnaire.

CM Sponsor-Defined Identifier

CMSPID

MedicationStatement.identifier

MedicationRequest.identifier

MedicationDispense.identifier

MedicationAdministration.identifier

Immunization.identifier

Reported Name of Drug, Med, or Therapy

CMTRT

MedicationStatement.medicationCodeableconcept

MedicationStatement.medication.medicationCodeableConcept

MedicationStatement.medicationReference

MedicationStatement.medication.medicationReference.resolve().code

MedicationRequest.medicationCodeableConcept

MedicationRequest.medication.medicationCodeableConcept

MedicationRequest.medicationReference

MedicationRequest.medication.medicationReference.resolve().code

MedicationDispense.medicationCodeableConcept

MedicationDispense.medication.medicationCodeableConcept

MedicationDispense.medicationReference

MedicationDispense.medication.medicationReference.resolve().code

MedicationAdministration.medicationCodeableConcept

MedicationAdministration.medication.medicationCodeableConcept

MedicationAdministration.medicationReference

MedicationAdministration.medication.medicationReference.resolve().code

Immunization.vaccineCode

CM Pre-Specified

CMPRESP

Would not expect to receive from the site.

CM Occurrence

CMOCCUR

MedicationStatement.status

In general, medication records won't exist unless the patient is taking the medication, though there is an ability to say a medication isn't currently being taken or shouldn't be taken

MedicationRequest.doNotPerform

MedicationRequest.doNotPerform=true

MedicationRequest.status

MedicationRequest.status IN {'entered-in-error'|'cancelled'|'stopped'}

MedicationDispense.status

MedicationRequest.status IN {entered-in-error'|'cancelled'|'stopped'}

MedicationAdministration.status

Immunization.status

Immunization.status IN {'completed'|'entered-in-error'}

Concomitant Meds Active Ingredients

CMINGRD

Medication.ingredient

MedicationStatement.medicationReference.resolve().ingredient.where(isActive)

Medication.ingredient

MedicationRequest.medicationReference.resolve().ingredient.where(isActive)

Medication.ingredient

MedicationDispense.medicationReference.resolve().ingredient.where(isActive)

Medication.ingredient

MedicationAdministration.medicationReference.resolve().ingredient.where(isActive)

Immunization.ingredient

Immunization.medicationReference.resolve().ingredient.where(isActive)

CM Indication

CMINDC

MedicationStatement.reasonCode

MedicationRequest.reasonCode

MedicationAdministration.reasonCode

Immunization.reasonCode

Related AdverseEvent ID

CMAENO

AdverseEvent.identifier

AdverseEvent.where(suspectEntity.instanceReference=MedicationX).identifier

This could match on AdverseEvent by code. (Note that the AdverseEvent points to the medication record, not the reverse

Related Medical History Event ID

CMMHNO

Condition.identifier

MedicationStatement.reasonReference.resolve().identifier

Condition.identifier

MedicationRequest.reasonReference.resolve().identifier

Condition.identifier

MedicationAdministration.reasonReference.resolve().identifier

Immunization.identifier

Immunization.reasonReference.resolve().identifier

CM Dose per Administration

CMDOSE

MedicationStatement.dosage

MedicationStatement.dosage.doseAndRate.doseQuantity

MedicationRequest.dosageInstruction

MedicationRequest.dosageInstruction.doseAndRate.doseQuantity

MedicationDispense.dosageInstruction

MedicationDispense.dosageInstruction.doseAndRate.doseQuantity

MedicationAdministration.dosage.dose

Immunization.doesQuantity

Immunization.doseQuantity

Concomitant Meds Dose Description

CMDSTXT

CMDOSTXT; CMDOSE

MedicationStatement.dosage

MedicationStatement.dosage.text

Requires combining multiple repetitions together

MedicationRequest.dosageInstruction

MedicationRequest.dosageInstruction.text

MedicationDispense.dosageInstruction

MedicationDispense.dosageInstruction.text

MedicationAdministration.dosage.text

CM Total Daily Dose

CMDOSTOT

MedicationStatement.dosage.maxDosePerPeriod

If Total Daily Dose is required by the sponsor, it may require collection of the drug dose and frequency to derive the CM Total Daily Dose.

MedicationRequest.dosage.maxDosePerPeriod

MedicationRequest.dosageInstruction.dosage.maxDosePerPeriod

MedicationDispense.dosage.maxDosePerPeriod

MedicationDispense.dosageInstruction.dosage.maxDosePerPeriod

Immunization.doseQuantity

CM Dose Units

CMDOSU

MedicationStatement.dosage.maxDosePerPeriod

MedicationStatement.dosage.maxDosePerPeriod.code

MedicationRequest.dosage.maxDosePerPeriod

MedicationRequest.dosage.maxDosePerPeriod.code

MedicationDispense.dosage.maxDosePerPeriod

MedicationDispense.dosage.maxDosePerPeriod.code

CM Dose Form

CMDOSFRM

Medication.form

MedicationStatement.medicationReference.resolve().form

Medication.form

MedicationRequest.medicationReference.resolve().form

Medication.form

MedicationDispense.medicationReference.resolve().form

CM Dosing Frequency per Interval

CMDOSFRQ

MedicationStatement.dosage

MedicationStatement.dosage.timing.frequency

MedicationRequest.dosageInstruction

MedicationRequest.dosageInstruction.timing.frequencey

MedicationDispense.dosageInstruction

MedicationDispense.dosageInstruction.timing.frequency

CM Route of Administration

CMROUTE

MedicationStatement.dosage

MedicationStatement.dosage.route

MedicationRequest.dosageInstruction

MedicationRequest.dosageInstruction.route

MedicationDispense.dosageInstruction

MedicationDispense.dosageInstruction.route

MedicationAdministration.dosage.route

Immunization.route

Concomitant Meds Start Date

CMSTDTC

MedicationStatement.effectiveDateTime

start includes both date and time, though time commonly won't be specified

MedicationStatement.effectivePeriod

MedicationStatement.effectivePeriod.start

MedicationRequest.dosageInstruction.timing

MedicationRequest.dosageInstruction.timing.repeat.boundsPeriod.start

MedicationDispense.dosageInstruction.timing

MedicationDispense.dosageInstruction.timing.repeat.boundsPeriod.start

Immunization.occurrenceDateTime

Immunization.occurrence.occurrenceDateTime

Immunization.occurrenceString

Immunization.occurrence.orrurrenceString

Concomitant Meds Start Time

CMSTDTC

MedicationStatement.effectiveDateTime

start includes both date and time, though time commonly won't be specified

MedicationStatement.effectivePeriod

MedicationStatement.effectivePeriod.start

MedicationRequest.dosageInstruction

MedicationRequest.dosageInstruction.timing.repeat.boundsPeriod.start

MedicationDispense.dosage.instruction

MedicationDispense.dosageInstruction.timing.repeat.boundsPeriod.start

Immunization.occurrenceDateTime

Immunization.occurrence.occurrenceDateTime

Immunization.occurrenceString

Immunization.occurrence.orrurrenceString

Concomitant Meds End Date

CMSTDTC

MedicationStatement.effectiveDateTime

end includes both date and time, though time commonly won't be specified

MedicationStatement.effectivePeriod

MedicationStatement.effectivePeriod.end

MedicationRequest.dosageInstruction

MedicationRequest.dosageInstruction.timing.repeat.boundsPeriod.end

MedicationDispense.dosage.instruction

MedicationDispense.dosageInstruction.timing.repeat.boundsPeriod.end

Immunization.occurrence

Immunization.occurrence.occurrenceDateTime

Immunization.occurrence.orrurrenceString

Concomitant Meds End Time

CMENDTC

MedicationStatement.effectiveDateTime

end includes both date and time, though time commonly won't be specified

MedicationStatement.effectivePeriod

MedicationStatement.effectivePeriod.end

MedicationRequest.dosageInstruction

MedicationRequest.dosageInstruction.timing.repeat.boundsPeriod.end

MedicationDispense.dosageInstruction

MedicationDispense.dosageInstruction.timing.repeat.boundsPeriod.end

Immunization.occurrence

Immunization.occurrence.occurrenceDateTime

Immunization.occurrence.orrurrenceString

Prior Concomitant Medications

CMPRIOR

CMSTRF; CMSTRTPT

This would need to be an extension added to the study extension on the medication resource - normally it is not captured except in the context of a study (and would be a study-specific assertion)

Ongoing Concomitant Medications

CMONGO

CMENRF; CMENRTPT

This would need to be an extension added to the study extension on the medication resource - normally it is not captured except in the context of a study (and would be a study-specific assertion)

Standardized Medication Name

CMDECOD

MedicationStatement.medicationCodeableConcept

MedicationStatement.medicationReference.resolve().code

We would not expect to receive these from the site.

Medication.code

MedicationStatement.medicationCodeableConcept

MedicationStatement.medicationReference.resolve().code

MedicationRequest.medicationCodeableConcept

MedicationRequest.medicationReference.resolve().code

Medication.code

MedicationRequest.medicationCodeableConcept

MedicationRequest.medicationReference.resolve().code

MedicationDispense.medicationCodeableConcept

MedicationDispense.medicationReference.resolve().code

Medication.code

MedicationDispense.medicationCodeableConcept

MedicationDispense.medicationReference.resolve().code

MedicationAdministration.medicationCodeableConcept

MedicationAdministration.medicationReference.resolve().code

Medication.code

MedicationAdministration.medicationCodeableConcept

MedicationAdministration.medicationReference.resolve().code

Immunization.vaccineCode

CM Medication Class

CMCLAS

MedicationStatement.medicationCodeableConcept

MedicationStatement.medicationReference.resolve().code

These *can* be provided as alternate codings, however typically encoding is performed by the sponsor and we would not expect to receive these from the site.

Medication.code

MedicationStatement.medicationCodeableConcept

MedicationStatement.medicationReference.resolve().code

MedicationRequest.medicationCodeableConcept

MedicationRequest.medicationReference.resolve().code

Medication.code

MedicationRequest.medicationCodeableConcept

MedicationRequest.medicationReference.resolve().code

MedicationDispense.medicationCodeableConcept

MedicationDispense.medicationReference.resolve().code

Medication.code

MedicationDispense.medicationCodeableConcept

MedicationDispense.medicationReference.resolve().code

MedicationAdministration.medicationCodeableConcept

MedicationAdministration.medicationReference.resolve().code

Medication.code

MedicationAdministration.medicationCodeableConcept

MedicationAdministration.medicationReference.resolve().code

Immunizations.vaccineCode

Immunization.vaccineCode

CM Medication Class Code

CMCLASCD

MedicationStatement.medicationCodeableConcept

MedicationStatement.medicationReference.resolve().code

These *can* be provided as alternate codings, however typically encoding is performed by the sponsor and we would not expect to receive these from the site.

Medication.code

MedicationStatement.medicationCodeableConcept

MedicationStatement.medicationReference.resolve().code

MedicationRequest.medicationCodeableConcept

MedicationRequest.medicationReference.resolve().code

Medication.code

MedicationRequest.medicationCodeableConcept

MedicationRequest.medicationReference.resolve().code

MedicationDispense.medicationCodeableConcept

MedicationDispense.medicationReference.resolve().code

Medication.code

MedicationDispense.medicationCodeableConcept

MedicationDispense.medicationReference.resolve().code

MedicationAdministration.medicationCodeableConcept

MedicationAdministration.medicationReference.resolve().code

Medication.code

MedicationAdministration.medicationCodeableConcept

MedicationAdministration.medicationReference.resolve().code

Immunization.vaccineCode

ATC Level 1 Description

CMATC1

SUPPCM.QVAL

Encoding is performed by the sponsor and we would not expect to receive these from the site.

ATC Level 1 Code

CMATC1CD

SUPPCM.QVAL

Encoding is performed by the sponsor and we would not expect to receive these from the site.

All coding levels are found in the same attribute as distinct codings. The granularity is distinguished by the code system or knowledge of the code

ATC Level 2 Description

CMATC2

SUPPCM.QVAL

Encoding is performed by the sponsor and we would not expect to receive these from the site.

ATC Level 2 Code

CMATC2CD

SUPPCM.QVAL

ATC Level 3 Description

CMATC3

SUPPCM.QVAL

Encoding is performed by the sponsor and we would not expect to receive these from the site.

ATC Level 3 Code

CMATC3CD

SUPPCM.QVAL

ATC Level 4 Description

CMATC4

SUPPCM.QVAL

Encoding is performed by the sponsor and we would not expect to receive these from the site.

ATC Level 4 Code

CMATC4CD

SUPPCM.QVAL

ATC Level 5 Description

CMATC5

SUPPCM.QVAL

Encoding is performed by the sponsor and we would not expect to receive these from the site.

ATC Level 5 Code

CMATC5CD

SUPPCM.QVAL