COVID-19 FHIR Profile Library IG Informative Version
1.0.0 - Informative US

This page is part of the Logica COVID-19 FHIR Profile Library IG (v1.0.0: Informative - Informative) based on FHIR R4. This is the current published version in its permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions

Lab profiles

Lab Profiles

These profiles are based on LOINC codes specific to SARS CoV 2(the causitive agent of COVID-19) and a few others related to it. Version 2.72 weas used to create this list.

For information about mapping COVID-19 laboratory test codes to a specific test, click here to download CDC’s up to date test mapping tool site supported by SHIELD.

Note about LOINC codes with unspecified specimens (xxx specimen)

Included in the list of profiles of the various COVID-19 specific laboratory tests are those that do not pre-coordinate the specimen type into the LOINC code. When using such codes, effort must be made to declare the specimen in a referenced Specimen instance (Observation.specimen(reference Specimen.type)).

Examples of the lab profiles

Two examples for SARS CoV2 testing have been created, one to represent quantitative types and one to represent coded or ordinal types of tests. Since all of the types are are well represented by these, examples for each profile were not created.

COVID-19 LOINC Profiles

LOINC codes with Quantitative results

LOINC Code Profile link
71776-9 Gamma interferon background [Units/volume] in Blood by Immunoassay
71774-4 Mitogen stimulated gamma interferon [Units/volume] corrected for background in Blood
71772-8 Mitogen stimulated gamma interferon [Units/volume] in Blood
94505-5 SARS-CoV-2 COVID-19 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
94506-3 SARS-CoV-2 COVID-19 IgM Ab [Units/volume] in Serum or Plasma by Immunoassay
94509-7 SARS-CoV-2 COVID-19 E gene [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
95522-9 SARS-CoV-2 COVID-19 N gene [Log #/volume] (viral load) in Respiratory specimen by NAA with probe detection
95521-1 SARS-CoV-2 COVID-19 N gene [#/volume] (viral load) in Respiratory specimen by NAA with probe detection
94510-5 SARS-CoV-2 COVID-19 N gene [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
94511-3 SARS-CoV-2 COVID-19 ORF1ab region [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
94644-2 SARS-CoV-2 COVID-19 ORF1ab region [Cycle Threshold #] in Respiratory specimen by NAA with probe detection
94646-7 SARS-CoV-2 COVID-19 RdRp gene [Cycle Threshold #] in Respiratory specimen by NAA with probe detection
94769-7 SARS-CoV-2 COVID-19 Ab [Units/volume] in Serum or Plasma by Immunoassay
94720-0 SARS-CoV-2 COVID-19 IgA Ab [Units/volume] in Serum or Plasma by Immunoassay
94311-8 SARS-CoV-2 COVID-19 N gene [Cycle Threshold #] in Unspecified specimen by Nucleic acid amplification using primer-probe set N1
94312-6 SARS-CoV-2 COVID-19 N gene [Cycle Threshold #] in Unspecified specimen by Nucleic acid amplification using primer-probe set N2
94645-9 SARS-CoV-2 COVID-19 RdRp gene [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
94745-7 SARS-CoV-2 COVID-19 RNA [Cycle Threshold#] in Respiratory specimen by NAA with probe detection
94819-0 SARS-CoV-2 COVID-19 RNA [Log#/volume] (viral load) in Unspecified specimen by NAA with probe detection
94746-5 SARS-CoV-2 COVID-19 RNA [Cycle Threshold#] in Unspecified specimen by NAA with probe detection
94642-6 SARS-CoV-2 COVID-19 S gene [Cycle Threshold #] in Respiratory specimen by NAA with probe detection
94643-4 SARS-CoV-2 COVID-19 S gene [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
95972-6 SARS CoV-2 stimulated gamma interferon release by T-cells [Units/volume] corrected for background in Blood
95973-4 SARS CoV-2 stimulated gamma interferon release by T-cells [Units/volume] in Blood
94313-4 SARS-like coronavirus N gene [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
98733-9 Percent neutralization by SARS coronavirus 2 spike protein RBD neutralizing antibody in Serum or Plasma by Immunoassay
95427-1 SARS-CoV-2 (COVID-19) IgA Ab [Titer] in Serum or Plasma by Immunofluorescence
96742-2 SARS-CoV-2 (COVID-19) IgG Ab [Mass/volume] in Serum or Plasma by Immunoassay
95429-7 SARS-CoV-2 (COVID-19) IgG Ab [Titer] in Serum or Plasma by Immunofluorescence
94506-3 SARS-CoV-2 (COVID19) IgM Ab [Units/volume] in Serum or Plasma by Immunoassay
95428-9 SARS-CoV-2 (COVID-19) IgM Ab [Titer] in Serum or Plasma by Immunofluorescence
95410-7 SARS-CoV-2 (COVID-19) neutralizing antibody [Titer] in Serum by pVNT
98734-7 SARS-CoV-2 (COVID-19) S protein RBD neutralizing antibody [Units/volume] in Serum or Plasma by Immunoassay
96957-6 SARS-CoV-2 (COVID-19) M gene [Presence] in Upper respiratory specimen by NAA with probe detection
96898-2 SARS-CoV-2 (COVID-19) N gene [Cycle Threshold #] in Oropharyngeal wash by NAA with probe detection
97104-4 SARS-CoV-2 (COVID-19) ORF1ab region [Units/volume] (viral load) in Upper respiratory specimen by NAA with probe detection
96899-0 SARS-CoV-2 (COVID-19) ORF1ab region [Cycle Threshold #] in Oropharyngeal wash by NAA with probe detection
96900-6 SARS-CoV-2 (COVID-19) S gene [Cycle Threshold #] in Oropharyngeal wash by NAA with probe detection
99773-4 SARS coronavirus 2 stimulated gamma interferon release by T-cells.Spike Ag spot count [#] corrected for background in Blood
98846-9 SARS coronavirus 2 stimulated gamma interferon release by Helper (CD4+) T-cells [Units/volume] corrected for background in Blood by Immunoassay
98847-7 SARS coronavirus 2 stimulated gamma interferon release by lymphocytes [Units/volume] corrected for background in Blood by Immunoassay

LOINC codes with coded results

LOINC Code Profile link
95423-0 Influenza virus A and B and SARS-CoV-2 COVID-19 identified in Respiratory specimen by NAA with probe detection
95380-2 Influenza virus A and B and SARS-CoV-2 COVID-19 and SARS-related CoV RNA panel - Respiratory specimen by NAA with probe detection
92142-9 Influenza virus A RNA [Presence] in Respiratory specimen by NAA with probe detection
92141-1 Influenza virus B RNA [Presence] in Respiratory specimen by NAA with probe detection
88891-7 Human coronavirus 229E+HKU1+OC43+NL63 RNA [Presence] in Nasopharynx by NAA with non-probe detection
82163-7 Human coronavirus 229E RNA [Presence] in Nasopharynx by NAA with non-probe detection
82161-1 Human coronavirus HKU1 RNA [Presence] in Nasopharynx by NAA with non-probe detection
82162-9 Human coronavirus NL63 RNA [Presence] in Nasopharynx by NAA with non-probe detection
82164-5 Human coronavirus OC43 RNA [Presence] in Nasopharynx by NAA with non-probe detection
80382-5 Influenza virus A Ag [Presence] in Nasopharynx by Rapid immunoassay
80383-3 Influenza virus B Ag [Presence] in Nasopharynx by Rapid immunoassay
92131-2 Respiratory syncytial virus RNA [Presence] in Respiratory specimen by NAA with probe detection
94562-6 SARS-CoV-2 COVID-19 IgA Ab [Presence] in Serum or Plasma by Immunoassay
95542-7 SARS-CoV-2 COVID-19 IgG+IgM Ab [Presence] in Serum, Plasma or Blood by Rapid immunoassay
94547-7 SARS-CoV-2 COVID-19 IgG+IgM Ab [Presence] in Serum or Plasma by Immunoassay
94507-1 SARS-CoV-2 COVID-19 IgG Ab [Presence] in Serum, Plasma or Blood by Rapid immunoassay
94563-4 SARS-CoV-2 COVID-19 IgG Ab [Presence] in Serum or Plasma by Immunoassay
95416-4 SARS-CoV-2 COVID-19 IgM Ab [Presence] in DBS by Immunoassay
94564-2 SARS-CoV-2 COVID-19 IgM Ab [Presence] in Serum or Plasma by Immunoassay
94508-9 SARS-CoV-2 COVID-19 IgM Ab [Presence] in Serum or Plasma by Rapid immunoassay
95411-5 SARS-CoV-2 COVID-19 neutralizing antibody [Presence] in Serum by pVNT
95825-6 SARS-CoV-2 COVID-19 Ab [Presence] in DBS by Immunoassay
96119-3 SARS-CoV-2 COVID-19 Ag [Presence] in Upper respiratory specimen by Immunoassay
94315-9 SARS-CoV-2 COVID-19 E gene [Presence] in Unspecified specimen by NAA with probe detection
95409-9 SARS-CoV-2 COVID-19 N gene [Presence] in Nose by NAA with probe detection
94533-7 SARS-CoV-2 COVID-19 N gene [Presence] in Respiratory specimen by NAA with probe detection
95425-5 SARS-CoV-2 COVID-19 N gene [Presence] in Saliva (oral fluid) by NAA with probe detection
94316-7 SARS-CoV-2 COVID-19 N gene [Presence] in Unspecified specimen by NAA with probe detection
95824-9 SARS-CoV-2 COVID-19 ORF1ab region [Presence] in Saliva (oral fluid) by NAA with probe detection
94639-2 SARS-CoV-2 COVID-19 ORF1ab region [Presence] in Unspecified specimen by NAA with probe detection
94534-5 SARS-CoV-2 COVID-19 RdRp gene [Presence] in Respiratory specimen by NAA with probe detection
96123-5 SARS-CoV-2 COVID-19 RdRp gene [Presence] in Upper respiratory specimen by NAA with probe detection
96091-4 SARS-CoV-2 COVID-19 RdRp gene [Presence] in Saliva (oral fluid) by NAA with probe detection
94314-2 SARS-CoV-2 COVID-19 RdRp gene [Presence] in Unspecified specimen by NAA with probe detection
95406-5 SARS-CoV-2 COVID-19 RNA [Presence] in Nose by NAA with probe detection
94565-9 SARS-CoV-2 COVID-19 RNA [Presence] in Nasopharynx by NAA with non-probe detection
95608-6 SARS-CoV-2 COVID-19 RNA [Presence] in Respiratory specimen by NAA with non-probe detection
95424-8 SARS-CoV-2 COVID-19 RNA [Presence] in Respiratory specimen by Sequencing
94500-6 SARS-CoV-2 COVID-19 RNA [Presence] in Respiratory specimen by NAA with probe detection
94309-2 SARS-CoV-2 COVID-19 RNA [Presence] in Unspecified specimen by NAA with probe detection
95609-4 SARS-CoV-2 COVID-19 S gene [Presence] in Respiratory specimen by Sequencing
95971-8 SARS CoV-2 stimulated gamma interferon [Presence] in Blood
95209-3 SARS-CoV + SARS-Cov-2 COVID-19 Ag [Presence] in Respiratory specimen by Rapid immunoassay
95125-1 SARS-CoV-2 COVID-19 IgA + IgM [Presence] in Serum or Plasma by Immunoassay
94768-9 SARS-CoV-2 COVID-19 IgA Ab [Presence] in Serum, Plasma, or Blood by Rapid imunoassay
94761-4 SARS-CoV-2 COVID-19 IgG Ab [Presence] in DBS by Immunoassay
94661-6 SARS-CoV-2 COVID-19 Ab [Interpretation] in Serum or Plasma
94762-2 SARS-CoV-2 COVID-19 Ab [Presence] in Serum or Plasma by Immunoassay
94558-4 SARS-CoV-2 COVID-19 Ag [Presence] in Respiratory specimen by Rapid immunoassay
94758-0 SARS-CoV-2 COVID-19 E gene [Presence] in Respiratory specimen by NAA with probe detection
94765-5 SARS-CoV-2 COVID-19 E gene [Presence] in Serum or Plasma by NAA with probe detection
94760-6 SARS-CoV-2 COVID-19 N gene [Presence] in Nasopharynx by NAA with probe detection
94757-2 SARS-CoV-2 COVID-19 N gene [Presence] in Respiratory specimen by Nucleaic acid amplification using CDC primer-probe set N2
96448-6 SARS-CoV-2 COVID-19 N gene [Presence] in Saliva (oral fluid) by Nucleic acid amplification using CDC primer-probe set N1
94766-3 SARS-CoV-2 COVID-19 N gene [Presence] in Serum or Plasma by NAA with probe detection
94307-6 SARS-CoV-2 COVID-19 N gene [Presence] in Unspecified specimen by Nucleic acid amplification using primer-probe set N1
94308-4 SARS-CoV-2 COVID-19 N gene [Presence] in Unspecified specimen by Nucleic acid amplification using primer-probe set N2
94756-4 SARS-CoV-2 COVID-19 N gene [Presence] in Respiratory specimen by Nucleic acid amplification using CDC primer-probe set N1
94559-2 SARS-CoV-2 COVID-19 ORF1ab region [Presence] in Respiratory specimen by NAA with probe detection
94763-0 SARS-CoV-2 COVID-19 [Presence] in Unspecified specimen by Organism specific culture
96120-1 SARS-CoV-2 COVID-19 RdRp gene [Presence] in Lower respiratory specimen by NAA with probe detection
94759-8 Sars-CoV-2 COVID-19 RNA [Presence] in Nasopharynx by NAA with probe detection
94845-5 SARS-CoV-2 COVID-19 RNA [Presence] in Saliva (viral load) in Unspecified specimen by NAA with probe detection
94822-4 SARS-CoV-2 COVID-19 RNA [Presence] in Saliva (oral fluid) by Sequencing
94660-8 SARS-CoV-2 COVID-19 RNA [Presence] in Serum or Plasma by NAA with probe detection
94640-0 SARS-CoV-2 COVID-19 S gene [Presence] in Respiratory specimen by NAA with probe detection
94767-1 SARS-CoV-2 COVID-19 S gene [Presence] in Serum or Plasma by NAA with probe detection
94641-8 SARS-CoV-2 COVID-19 S gene [Presence] in Unspecified specimen by NAA with probe detection
95970-0 SARS-CoV-2 COVID-19 specific TCRB gene rearrangements [Presence] in Blood by Sequencing
96603-6 SARS-CoV-2 COVID-19 S protein RBD neutralizing antibody [Presence] in Serum or Plasma by Immunoassay
94764-8 SARS-coV-2 COVID-19 whole genome [Nucleiotide sequence] in Isolate by Sequencing
94310-0 SARS-like coronavirus N gene [Presence] in Unspecified specimen by NAA with probe detection
95823-1 SARS-related coronavirus E gene [Presence] in Saliva (oral fluid) by NAA with probe detection
94502-2 SARS-related coronavirus RNA [Presence] in Respiratory specimen by NAA with probe detection
94532-9 SARS-related coronavirus+MERS coronavirus RNA [Presence] in Respiratory specimen by NAA with probe detection
94647-5 SARS-related coronavirus RNA [Presence] in Unspecified specimen by NAA with probe detection
96121-9 SARS-related coronavirus E gene [Presence] in Lower respiratory specimen by NAA with probe detection
96122-7 SARS-related coronavirus E gene [Presence] in Upper respiratory specimen by NAA with probe detection
98069-8 SARS-CoV-2 (COVID-19) Ab [Presence] in Saliva (oral fluid) by Rapid immunoassay
97097-0 SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
96896-6 SARS-CoV-2 (COVID-19) clade [Type] in Specimen by Molecular genetics method
96763-8 SARS-CoV-2 (COVID-19) E gene [Presence] in Respiratory specimen by NAA with probe detection
96895-8 SARS-CoV-2 (COVID-19) lineage [Identifier] in Specimen by Molecular genetics method
95521-1 SARS-CoV-2 (COVID-19) N gene [#/volume] (viral load) in Respiratory specimen by NAA with probe detection
96986-5 SARS-CoV-2 (COVID-19) N gene [Presence] in Nose by NAA with non-probe detection
98494-8 SARS-CoV-2 (COVID-19) ORF1a region [Presence] in Saliva (oral fluid) by NAA with probe detection
98493-0 SARS-CoV-2 (COVID-19) ORF1b region [Presence] in Saliva (oral fluid) by NAA with probe detection
96797-6 SARS-CoV-2 (COVID-19) RNA [Presence] in Oropharyngeal wash by NAA with probe detection
96751-3 SARS-CoV-2 (COVID-19) S gene mutation detected [Identifier] in Specimen by Molecular genetics method
96752-1 SARS-CoV-2 (COVID-19) S gene mutation [Presence] in Specimen by Molecular genetics method
96765-3 SARS-CoV-2 (COVID-19) S gene [Presence] in Saliva (oral fluid) by NAA with probe detection
99597-7 SARS-CoV-2 (COVID-19) S protein IgG Ab [Presence] in Serum or Plasma by Immunoassay
99772-6 SARS-CoV-2 stimulated gamma interferon [Interpretation] in Blood Qualitative
96741-4 SARS-CoV-2 (COVID-19) variant [Type] in Specimen by Sequencing
96958-4 SARS-CoV-2 (COVID-19) N gene [Presence] in Saliva (oral fluid) by Nucleic acid amplification using CDC primer-probe set N2
97098-8 SARS-CoV-2 (COVID-19) Nsp2 gene [Presence] in Upper respiratory specimen by NAA with probe detection
99596-9 SARS-CoV-2 (COVID-19) N protein IgG Ab [Presence] in Serum or Plasma by Immunoassay
98132-4 SARS-CoV-2 (COVID-19) ORF1a region [Presence] in Respiratory specimen by NAA with probe detection
98131-6 SARS-CoV-2 (COVID-19) ORF1b region [Presence] in Respiratory specimen by NAA with probe detection
99314-7 SARS-CoV-2 (COVID-19) RdRp gene mutation detected [Identifier] in Specimen by Molecular genetics method

Panel LOINC codes

LOINC Code Profile link
95941-1 Influenza virus A and B and SARS-CoV-2 COVID-19 and Respiratory syncytial virus RNA panel - Respiratory specimen by NAA with probe detection
95942-9 Influenza virus A and B and SARS-CoV+SARS-CoV-2 COVID-19 Ag panel - Upper respiratory specimen by Rapid immunoassay
95422-2 Influenza virus A and B RNA and SARS-CoV-2 COVID-19 N gene panel - Respiratory specimen by NAA with probe detection
94503-0 SARS-CoV-2 COVID-19 IgG and IgM panel - Serum or Plasma Qualitative by Rapid immunoassay
94504-8 SARS-CoV-2 COVID-19 IgG and IgM panel - Serum or Plasma by Immunoassay
96118-5 SARS-CoV-2 COVID-19 Ab panel - DBS by Immunoassay
94531-1 SARS-CoV-2 COVID-19 RNA panel - Respiratory specimen by NAA with probe detection
95826-4 SARS-CoV-2 COVID-19 RNA panel - Saliva (oral fluid) by NAA with probe detection
95974-2 SARS CoV-2 stimulated gamma interferon panel - Blood
96094-8 SARS-CoV-2 COVID-19 and SARS-related CoV RNA panel - Respiratory specimen by NAA with probe detection
94306-8 SARS-Cov-2 COVID-19 RNA panel - Unspecified specimen by NAA with probe detection
97099-6 Influenza virus A and B and SARS-CoV-2 (COVID-19) Ag panel - Upper respiratory specimen by Rapid immunoassay
96897-4 SARS-CoV-2 (COVID-19) RNA panel - Oropharyngeal wash by NAA with probe detection
96894-1 SARS-CoV-2 (COVID-19) sequencing and identification panel - Specimen by Molecular genetics method
98080-5 SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Saliva (oral fluid) by NAA with probe detection

Other LOINC codes

LOINC Code Profile link
95427-1 SARS-CoV-2 COVID-19 IgA Ab [Titer] in Serum or Plasma by Immunofluorescence
95429-7 SARS-CoV-2 COVID-19 IgG Ab [Titer] in Serum or Plasma by Immunofluorescence
95428-9 SARS-CoV-2 COVID-19 IgM Ab [Titer] in Serum or Plasma by Immunofluorescence
95410-7 SARS-CoV-2 COVID-19 neutralizing antibody [Titer] in Serum by pVNT
96755-4 SARS-CoV-2 (COVID-19) variant interpretation in Specimen Narrative
98732-1 SARS-CoV-2 (COVID-19) S protein RBD neutralizing antibody [Titer] in Serum or Plasma by Immunoassay
98062-3 Sequencing Study Identifier
96766-1 GISAID Sequence Accession Number