Extensions for Using Data Elements from FHIR R5 in FHIR R4 - Downloaded Version null See the Directory of published versions

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Resource Profile: Profile_R5_SubstanceDefinition_R4_SubstanceSpecification

This cross-version profile allows R5 SubstanceDefinition content to be represented via FHIR R4 SubstanceSpecification resources.

Usages:

• Refer to this Profile: R5: Information about use of the product in relation to other therapies described as part of the contraindication (new), R5: Specifics for when this is a contraindication (new), R5: The substance that comprises this ingredient (new), R5: Any component of the drug product which is not the chemical entity defined as the drug substance, or an excipient in the drug product (new)... Show 3 more, R5: focus additional types, R5: code additional types and R5: A pointer to another substance, as a resource or a representational code (new)

You can also check for usages in the FHIR IG Statistics

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

• Key Elements Table
• Differential Table
• Snapshot Table
• Statistics/References
• All

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
SubstanceSpecification		0..*	SubstanceSpecification(4.0.1)	The detailed description of a substance, typically at a level beyond what is used for prescribing
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:version		0..1	string	R5: A business level version identifier of the substance (new) URL: http://hl7.org/fhir/StructureDefinition/artifact-version Constraints: ext-1
extension:classification		0..*	CodeableConcept	R5: A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.classification Constraints: ext-1
extension:grade		0..*	CodeableConcept	R5: The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.grade Binding: R5SubstanceGradeForR4 (0.1.0) (example): The quality standard, established benchmark, to which a substance complies Constraints: ext-1
extension:informationSource		0..*	Reference(Cross-version Profile for R5.Citation for use in FHIR R4(0.1.0) | Basic)	R5: Supporting literature (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.informationSource Constraints: ext-1
extension:note		0..*	Annotation	R5: Textual comment about the substance's catalogue or registry record (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.note Constraints: ext-1
extension:manufacturer		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: The entity that creates, makes, produces or fabricates the substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.manufacturer Constraints: ext-1
extension:supplier		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: An entity that is the source for the substance. It may be different from the manufacturer (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.supplier Constraints: ext-1
extension:characterization		0..*	(Complex)	R5: General specifications for this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.characterization Constraints: ext-1
extension:referenceInformation		0..1	Reference(Cross-version Profile for R5.SubstanceReferenceInformation for use in FHIR R4(0.1.0) | Basic)	R5: General information detailing this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.referenceInformation Constraints: ext-1
extension:nucleicAcid		0..1	Reference(Cross-version Profile for R5.SubstanceNucleicAcid for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to nucleic acids (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.nucleicAcid Constraints: ext-1
extension:polymer		0..1	Reference(Cross-version Profile for R5.SubstancePolymer for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to polymers (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.polymer Constraints: ext-1
extension:protein		0..1	Reference(Cross-version Profile for R5.SubstanceProtein for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to proteins (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.protein Constraints: ext-1
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored Constraints: ext-1
Documentation for this format

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	SubstanceSpecification	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	SubstanceSpecification	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	SubstanceSpecification	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	SubstanceSpecification	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	SubstanceSpecification	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	SubstanceSpecification.implicitRules, SubstanceSpecification.extension, SubstanceSpecification.extension:version, SubstanceSpecification.extension:classification, SubstanceSpecification.extension:grade, SubstanceSpecification.extension:informationSource, SubstanceSpecification.extension:note, SubstanceSpecification.extension:manufacturer, SubstanceSpecification.extension:supplier, SubstanceSpecification.extension:characterization, SubstanceSpecification.extension:referenceInformation, SubstanceSpecification.extension:nucleicAcid, SubstanceSpecification.extension:polymer, SubstanceSpecification.extension:protein, SubstanceSpecification.modifierExtension	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	SubstanceSpecification.extension, SubstanceSpecification.extension:version, SubstanceSpecification.extension:classification, SubstanceSpecification.extension:grade, SubstanceSpecification.extension:informationSource, SubstanceSpecification.extension:note, SubstanceSpecification.extension:manufacturer, SubstanceSpecification.extension:supplier, SubstanceSpecification.extension:characterization, SubstanceSpecification.extension:referenceInformation, SubstanceSpecification.extension:nucleicAcid, SubstanceSpecification.extension:polymer, SubstanceSpecification.extension:protein, SubstanceSpecification.modifierExtension	Must have either extensions or value[x], not both	extension.exists() != value.exists()

This structure is derived from SubstanceSpecification

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
SubstanceSpecification		0..*	SubstanceSpecification(4.0.1)	The detailed description of a substance, typically at a level beyond what is used for prescribing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:version		0..1	string	R5: A business level version identifier of the substance (new) URL: http://hl7.org/fhir/StructureDefinition/artifact-version
extension:classification		0..*	CodeableConcept	R5: A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.classification
extension:grade		0..*	CodeableConcept	R5: The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.grade Binding: R5SubstanceGradeForR4 (0.1.0) (example): The quality standard, established benchmark, to which a substance complies
extension:informationSource		0..*	Reference(Cross-version Profile for R5.Citation for use in FHIR R4(0.1.0) | Basic)	R5: Supporting literature (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.informationSource
extension:note		0..*	Annotation	R5: Textual comment about the substance's catalogue or registry record (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.note
extension:manufacturer		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: The entity that creates, makes, produces or fabricates the substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.manufacturer
extension:supplier		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: An entity that is the source for the substance. It may be different from the manufacturer (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.supplier
extension:characterization		0..*	(Complex)	R5: General specifications for this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.characterization
extension:referenceInformation		0..1	Reference(Cross-version Profile for R5.SubstanceReferenceInformation for use in FHIR R4(0.1.0) | Basic)	R5: General information detailing this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.referenceInformation
extension:nucleicAcid		0..1	Reference(Cross-version Profile for R5.SubstanceNucleicAcid for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to nucleic acids (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.nucleicAcid
extension:polymer		0..1	Reference(Cross-version Profile for R5.SubstancePolymer for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to polymers (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.polymer
extension:protein		0..1	Reference(Cross-version Profile for R5.SubstanceProtein for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to proteins (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.protein
identifier
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:identifier		0..*	Identifier	R5: identifier URL: http://hl7.org/fhir/StructureDefinition/artifact-identifier
status
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:status		0..1	code	R5: Status of substance within the catalogue e.g. active, retired URL: http://hl7.org/fhir/StructureDefinition/artifact-status Binding: PublicationStatus (required): The lifecycle status of an artifact.
description
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:description		0..1	markdown	R5: description URL: http://hl7.org/fhir/StructureDefinition/artifact-description
moiety
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:measurementType		0..1	CodeableConcept	R5: The measurement type of the quantitative value (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.moiety.measurementType Binding: R5SubstanceAmountTypeForR4 (0.1.0) (example): The relationship between two substance types.
property
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:type		1..1	CodeableConcept	R5: A code expressing the type of property (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.type
extension:value		0..1	CodeableConcept, Quantity, date, boolean, Attachment	R5: A value for the property (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.value
structure
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:technique		0..*	CodeableConcept	R5: The method used to find the structure e.g. X-ray, NMR (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.technique Binding: R5SubstanceStructureTechniqueForR4 (0.1.0) (example): The method used to elucidate the structure of the drug substance.
extension:sourceDocument		0..*	Reference(Cross-version Profile for R5.DocumentReference for use in FHIR R4(0.1.0) | Media)	R5: Source of information for the structure (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.sourceDocument
representation
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:format		0..1	CodeableConcept	R5: The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.format Binding: R5SubstanceRepresentationFormatForR4 (0.1.0) (example): A format of a substance representation.
extension:document		0..1	Reference(Cross-version Profile for R5.DocumentReference for use in FHIR R4(0.1.0) | Media)	R5: An attachment with the structural representation e.g. a structure graphic or AnIML file (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.document
code
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:note		0..*	Annotation	R5: Any comment can be provided in this field (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.code.note
source
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:source		0..*	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference
name
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:name		0..*	string	R5: name URL: http://hl7.org/fhir/StructureDefinition/artifact-name
language
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:language		0..*	CodeableConcept	R5: Human language that the name is written in URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.name.language
source
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:source		0..*	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference
molecularWeight
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:method		0..1	CodeableConcept	R5: The method by which the weight was determined (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.method Binding: R5SubstanceWeightMethodForR4 (0.1.0) (example): The method by which the substance weight was measured.
extension:type		0..1	CodeableConcept	R5: Type of molecular weight e.g. exact, average, weight average (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.type Binding: R5SubstanceWeightTypeForR4 (0.1.0) (example): The type of substance weight measurement.
extension:amount		1..1	Quantity	R5: Used to capture quantitative values for a variety of elements (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.amount
relationship
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:substanceDefinition		0..1	Reference(Cross-version Profile for R5.SubstanceDefinition for use in FHIR R4(0.1.0) | SubstanceSpecification), CodeableConcept	R5: A pointer to another substance, as a resource or a representational code (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.substanceDefinition
extension:type		1..1	CodeableConcept	R5: For example "salt to parent", "active moiety" (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.type Binding: R5SubstanceRelationshipTypeForR4 (0.1.0) (example): The relationship between two substance types.
extension:ratioHighLimitAmount		0..1	Ratio	R5: For use when the numeric has an uncertain range (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.ratioHighLimitAmount
extension:comparator		0..1	CodeableConcept	R5: An operator for the amount, for example "average", "approximately", "less than" (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.comparator Binding: R5SubstanceAmountTypeForR4 (0.1.0) (example): The relationship between two substance types.
source
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:source		0..*	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference
sourceMaterial
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:type		0..1	CodeableConcept	R5: Classification of the origin of the raw material. e.g. cat hair is an Animal source type (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.type Binding: R5SubstanceSourceMaterialTypeForR4 (0.1.0) (example): A classification that provides the origin of the substance raw material.
extension:genus		0..1	CodeableConcept	R5: The genus of an organism e.g. the Latin epithet of the plant/animal scientific name (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.genus Binding: R5SubstanceSourceMaterialGenusForR4 (0.1.0) (example): The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
extension:species		0..1	CodeableConcept	R5: The species of an organism e.g. the Latin epithet of the species of the plant/animal (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.species Binding: R5SubstanceSourceMaterialSpeciesForR4 (0.1.0) (example): A species of origin a substance raw material.
extension:part		0..1	CodeableConcept	R5: An anatomical origin of the source material within an organism (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.part Binding: R5SubstanceSourceMaterialPartForR4 (0.1.0) (example): An anatomical origin of the source material within an organism.
extension:countryOfOrigin		0..*	CodeableConcept	R5: The country or countries where the material is harvested (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.countryOfOrigin
Documentation for this format

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
SubstanceSpecification		0..*	SubstanceSpecification(4.0.1)	The detailed description of a substance, typically at a level beyond what is used for prescribing
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:version		0..1	string	R5: A business level version identifier of the substance (new) URL: http://hl7.org/fhir/StructureDefinition/artifact-version Constraints: ext-1
extension:classification		0..*	CodeableConcept	R5: A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.classification Constraints: ext-1
extension:grade		0..*	CodeableConcept	R5: The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.grade Binding: R5SubstanceGradeForR4 (0.1.0) (example): The quality standard, established benchmark, to which a substance complies Constraints: ext-1
extension:informationSource		0..*	Reference(Cross-version Profile for R5.Citation for use in FHIR R4(0.1.0) | Basic)	R5: Supporting literature (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.informationSource Constraints: ext-1
extension:note		0..*	Annotation	R5: Textual comment about the substance's catalogue or registry record (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.note Constraints: ext-1
extension:manufacturer		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: The entity that creates, makes, produces or fabricates the substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.manufacturer Constraints: ext-1
extension:supplier		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: An entity that is the source for the substance. It may be different from the manufacturer (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.supplier Constraints: ext-1
extension:characterization		0..*	(Complex)	R5: General specifications for this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.characterization Constraints: ext-1
extension:referenceInformation		0..1	Reference(Cross-version Profile for R5.SubstanceReferenceInformation for use in FHIR R4(0.1.0) | Basic)	R5: General information detailing this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.referenceInformation Constraints: ext-1
extension:nucleicAcid		0..1	Reference(Cross-version Profile for R5.SubstanceNucleicAcid for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to nucleic acids (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.nucleicAcid Constraints: ext-1
extension:polymer		0..1	Reference(Cross-version Profile for R5.SubstancePolymer for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to polymers (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.polymer Constraints: ext-1
extension:protein		0..1	Reference(Cross-version Profile for R5.SubstanceProtein for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to proteins (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.protein Constraints: ext-1
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored Constraints: ext-1
identifier	Σ	0..1	Identifier	Identifier by which this substance is known
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:identifier		0..*	Identifier	R5: identifier URL: http://hl7.org/fhir/StructureDefinition/artifact-identifier Constraints: ext-1
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
type	Σ	0..1	CodeableConcept	Description of identifier Binding: Identifier Type Codes (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.
system	Σ	0..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient
value	Σ	0..1	string	The value that is unique Example General: 123456
period	Σ	0..1	Period	Time period when id is/was valid for use
assigner	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)
type	Σ	0..1	CodeableConcept	High level categorization, e.g. polymer or nucleic acid
status	Σ	0..1	CodeableConcept	Status of substance within the catalogue e.g. approved
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:status		0..1	code	R5: Status of substance within the catalogue e.g. active, retired URL: http://hl7.org/fhir/StructureDefinition/artifact-status Binding: PublicationStatus (required): The lifecycle status of an artifact. Constraints: ext-1
coding	Σ	0..*	Coding	Code defined by a terminology system
text	Σ	0..1	string	Plain text representation of the concept
domain	Σ	0..1	CodeableConcept	If the substance applies to only human or veterinary use
description	Σ	0..1	string	Textual description of the substance
id		0..1	string	xml:id (or equivalent in JSON)
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:description		0..1	markdown	R5: description URL: http://hl7.org/fhir/StructureDefinition/artifact-description Constraints: ext-1
value		0..1	string	Primitive value for string Max Length:1048576
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
comment	Σ	0..1	string	Textual comment about this record of a substance
moiety	Σ	0..*	BackboneElement	Moiety, for structural modifications
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:measurementType		0..1	CodeableConcept	R5: The measurement type of the quantitative value (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.moiety.measurementType Binding: R5SubstanceAmountTypeForR4 (0.1.0) (example): The relationship between two substance types. Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
role	Σ	0..1	CodeableConcept	Role that the moiety is playing
identifier	Σ	0..1	Identifier	Identifier by which this moiety substance is known
name	Σ	0..1	string	Textual name for this moiety substance
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type
molecularFormula	Σ	0..1	string	Molecular formula
amount[x]	Σ	0..1		Quantitative value for this moiety
amountQuantity			Quantity
amountString			string
property	Σ	0..*	BackboneElement	General specifications for this substance, including how it is related to other substances
id		0..1	string	Unique id for inter-element referencing
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:type		1..1	CodeableConcept	R5: A code expressing the type of property (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.type Constraints: ext-1
extension:value		0..1	CodeableConcept, Quantity, date, boolean, Attachment	R5: A value for the property (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.value Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
category	Σ	0..1	CodeableConcept	A category for this property, e.g. Physical, Chemical, Enzymatic
code	Σ	0..1	CodeableConcept	Property type e.g. viscosity, pH, isoelectric point
parameters	Σ	0..1	string	Parameters that were used in the measurement of a property (e.g. for viscosity: measured at 20C with a pH of 7.1)
definingSubstance[x]	Σ	0..1		A substance upon which a defining property depends (e.g. for solubility: in water, in alcohol)
definingSubstanceReference			Reference(SubstanceSpecification | Substance)
definingSubstanceCodeableConcept			CodeableConcept
amount[x]	Σ	0..1		Quantitative value for this property
amountQuantity			Quantity
amountString			string
referenceInformation	Σ	0..1	Reference(SubstanceReferenceInformation)	General information detailing this substance
structure	Σ	0..1	BackboneElement	Structural information
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:technique		0..*	CodeableConcept	R5: The method used to find the structure e.g. X-ray, NMR (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.technique Binding: R5SubstanceStructureTechniqueForR4 (0.1.0) (example): The method used to elucidate the structure of the drug substance. Constraints: ext-1
extension:sourceDocument		0..*	Reference(Cross-version Profile for R5.DocumentReference for use in FHIR R4(0.1.0) | Media)	R5: Source of information for the structure (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.sourceDocument Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type
molecularFormula	Σ	0..1	string	Molecular formula
molecularFormulaByMoiety	Σ	0..1	string	Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical, each moiety separated by a dot
isotope	Σ	0..*	BackboneElement	Applicable for single substances that contain a radionuclide or a non-natural isotopic ratio
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
identifier	Σ	0..1	Identifier	Substance identifier for each non-natural or radioisotope
name	Σ	0..1	CodeableConcept	Substance name for each non-natural or radioisotope
substitution	Σ	0..1	CodeableConcept	The type of isotopic substitution present in a single substance
halfLife	Σ	0..1	Quantity	Half life - for a non-natural nuclide
molecularWeight	Σ	0..1	BackboneElement	The molecular weight or weight range (for proteins, polymers or nucleic acids)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
method	Σ	0..1	CodeableConcept	The method by which the molecular weight was determined
type	Σ	0..1	CodeableConcept	Type of molecular weight such as exact, average (also known as. number average), weight average
amount	Σ	0..1	Quantity	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field
molecularWeight	Σ	0..1	See molecularWeight (SubstanceSpecification)	The molecular weight or weight range (for proteins, polymers or nucleic acids)
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
representation	Σ	0..*	BackboneElement	Molecular structural representation
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:format		0..1	CodeableConcept	R5: The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.format Binding: R5SubstanceRepresentationFormatForR4 (0.1.0) (example): A format of a substance representation. Constraints: ext-1
extension:document		0..1	Reference(Cross-version Profile for R5.DocumentReference for use in FHIR R4(0.1.0) | Media)	R5: An attachment with the structural representation e.g. a structure graphic or AnIML file (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.document Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
type	Σ	0..1	CodeableConcept	The type of structure (e.g. Full, Partial, Representative)
representation	Σ	0..1	string	The structural representation as text string in a format e.g. InChI, SMILES, MOLFILE, CDX
attachment	Σ	0..1	Attachment	An attached file with the structural representation
code	Σ	0..*	BackboneElement	Codes associated with the substance
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:note		0..*	Annotation	R5: Any comment can be provided in this field (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.code.note Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
code	Σ	0..1	CodeableConcept	The specific code
status	Σ	0..1	CodeableConcept	Status of the code assignment
statusDate	Σ	0..1	dateTime	The date at which the code status is changed as part of the terminology maintenance
comment	Σ	0..1	string	Any comment can be provided in this field, if necessary
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:source		0..1	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference Constraints: ext-1
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	Σ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
name	Σ	0..*	BackboneElement	Names applicable to this substance
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:name		0..*	string	R5: name URL: http://hl7.org/fhir/StructureDefinition/artifact-name Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
name	Σ	1..1	string	The actual name
type	Σ	0..1	CodeableConcept	Name type
status	Σ	0..1	CodeableConcept	The status of the name
preferred	Σ	0..1	boolean	If this is the preferred name for this substance
language	Σ	0..*	CodeableConcept	Language of the name
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:language		0..*	CodeableConcept	R5: Human language that the name is written in URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.name.language Constraints: ext-1
coding	Σ	0..*	Coding	Code defined by a terminology system
text	Σ	0..1	string	Plain text representation of the concept
domain	Σ	0..*	CodeableConcept	The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive
jurisdiction	Σ	0..*	CodeableConcept	The jurisdiction where this name applies
synonym	Σ	0..*	See name (SubstanceSpecification)	A synonym of this name
translation	Σ	0..*	See name (SubstanceSpecification)	A translation for this name
official	Σ	0..*	BackboneElement	Details of the official nature of this name
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
authority	Σ	0..1	CodeableConcept	Which authority uses this official name
status	Σ	0..1	CodeableConcept	The status of the official name
date	Σ	0..1	dateTime	Date of official name change
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:source		0..1	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference Constraints: ext-1
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	Σ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
molecularWeight	Σ	0..*	BackboneElement	The molecular weight or weight range (for proteins, polymers or nucleic acids)
id		0..1	string	Unique id for inter-element referencing
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:method		0..1	CodeableConcept	R5: The method by which the weight was determined (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.method Binding: R5SubstanceWeightMethodForR4 (0.1.0) (example): The method by which the substance weight was measured. Constraints: ext-1
extension:type		0..1	CodeableConcept	R5: Type of molecular weight e.g. exact, average, weight average (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.type Binding: R5SubstanceWeightTypeForR4 (0.1.0) (example): The type of substance weight measurement. Constraints: ext-1
extension:amount		1..1	Quantity	R5: Used to capture quantitative values for a variety of elements (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.amount Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
method	Σ	0..1	CodeableConcept	The method by which the molecular weight was determined
type	Σ	0..1	CodeableConcept	Type of molecular weight such as exact, average (also known as. number average), weight average
amount	Σ	0..1	Quantity	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field
relationship	Σ	0..*	BackboneElement	A link between this substance and another, with details of the relationship
id		0..1	string	Unique id for inter-element referencing
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:substanceDefinition		0..1	Reference(Cross-version Profile for R5.SubstanceDefinition for use in FHIR R4(0.1.0) | SubstanceSpecification), CodeableConcept	R5: A pointer to another substance, as a resource or a representational code (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.substanceDefinition Constraints: ext-1
extension:type		1..1	CodeableConcept	R5: For example "salt to parent", "active moiety" (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.type Binding: R5SubstanceRelationshipTypeForR4 (0.1.0) (example): The relationship between two substance types. Constraints: ext-1
extension:ratioHighLimitAmount		0..1	Ratio	R5: For use when the numeric has an uncertain range (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.ratioHighLimitAmount Constraints: ext-1
extension:comparator		0..1	CodeableConcept	R5: An operator for the amount, for example "average", "approximately", "less than" (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.comparator Binding: R5SubstanceAmountTypeForR4 (0.1.0) (example): The relationship between two substance types. Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
substance[x]	Σ	0..1		A pointer to another substance, as a resource or just a representational code
substanceReference			Reference(SubstanceSpecification)
substanceCodeableConcept			CodeableConcept
relationship	Σ	0..1	CodeableConcept	For example "salt to parent", "active moiety", "starting material"
isDefining	Σ	0..1	boolean	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible substance relationships
amount[x]	Σ	0..1		A numeric factor for the relationship, for instance to express that the salt of a substance has some percentage of the active substance in relation to some other
amountQuantity			Quantity
amountRange			Range
amountRatio			Ratio
amountString			string
amountRatioLowLimit	Σ	0..1	Ratio	For use when the numeric
amountType	Σ	0..1	CodeableConcept	An operator for the amount, for example "average", "approximately", "less than"
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:source		0..1	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference Constraints: ext-1
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	Σ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
nucleicAcid	Σ	0..1	Reference(SubstanceNucleicAcid)	Data items specific to nucleic acids
polymer	Σ	0..1	Reference(SubstancePolymer)	Data items specific to polymers
protein	Σ	0..1	Reference(SubstanceProtein)	Data items specific to proteins
sourceMaterial	Σ	0..1	Reference(SubstanceSourceMaterial)	Material or taxonomic/anatomical source for the substance
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:type		0..1	CodeableConcept	R5: Classification of the origin of the raw material. e.g. cat hair is an Animal source type (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.type Binding: R5SubstanceSourceMaterialTypeForR4 (0.1.0) (example): A classification that provides the origin of the substance raw material. Constraints: ext-1
extension:genus		0..1	CodeableConcept	R5: The genus of an organism e.g. the Latin epithet of the plant/animal scientific name (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.genus Binding: R5SubstanceSourceMaterialGenusForR4 (0.1.0) (example): The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name. Constraints: ext-1
extension:species		0..1	CodeableConcept	R5: The species of an organism e.g. the Latin epithet of the species of the plant/animal (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.species Binding: R5SubstanceSourceMaterialSpeciesForR4 (0.1.0) (example): A species of origin a substance raw material. Constraints: ext-1
extension:part		0..1	CodeableConcept	R5: An anatomical origin of the source material within an organism (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.part Binding: R5SubstanceSourceMaterialPartForR4 (0.1.0) (example): An anatomical origin of the source material within an organism. Constraints: ext-1
extension:countryOfOrigin		0..*	CodeableConcept	R5: The country or countries where the material is harvested (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.countryOfOrigin Constraints: ext-1
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	Σ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
SubstanceSpecification.​language	Base	preferred	Common Languages	📍4.0.1	tx.fhir.org
SubstanceSpecification.​identifier.use	Base	required	IdentifierUse	📍4.0.1	FHIR Std.
SubstanceSpecification.​identifier.type	Base	extensible	IdentifierType	📍4.0.1	FHIR Std.
SubstanceSpecification.​code.source.type	Base	extensible	ResourceType	📍4.0.1	tx.fhir.org
SubstanceSpecification.​name.source.type	Base	extensible	ResourceType	📍4.0.1	tx.fhir.org
SubstanceSpecification.​relationship.source.​type	Base	extensible	ResourceType	📍4.0.1	tx.fhir.org
SubstanceSpecification.​sourceMaterial.type	Base	extensible	ResourceType	📍4.0.1	tx.fhir.org

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	SubstanceSpecification	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	SubstanceSpecification	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	SubstanceSpecification	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	SubstanceSpecification	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	SubstanceSpecification	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	SubstanceSpecification.meta, SubstanceSpecification.implicitRules, SubstanceSpecification.language, SubstanceSpecification.text, SubstanceSpecification.extension, SubstanceSpecification.extension:version, SubstanceSpecification.extension:classification, SubstanceSpecification.extension:grade, SubstanceSpecification.extension:informationSource, SubstanceSpecification.extension:note, SubstanceSpecification.extension:manufacturer, SubstanceSpecification.extension:supplier, SubstanceSpecification.extension:characterization, SubstanceSpecification.extension:referenceInformation, SubstanceSpecification.extension:nucleicAcid, SubstanceSpecification.extension:polymer, SubstanceSpecification.extension:protein, SubstanceSpecification.modifierExtension, SubstanceSpecification.identifier, SubstanceSpecification.identifier.extension, SubstanceSpecification.identifier.extension:identifier, SubstanceSpecification.identifier.use, SubstanceSpecification.identifier.type, SubstanceSpecification.identifier.system, SubstanceSpecification.identifier.value, SubstanceSpecification.identifier.period, SubstanceSpecification.identifier.assigner, SubstanceSpecification.type, SubstanceSpecification.status, SubstanceSpecification.status.extension, SubstanceSpecification.status.extension:status, SubstanceSpecification.status.coding, SubstanceSpecification.status.text, SubstanceSpecification.domain, SubstanceSpecification.description, SubstanceSpecification.description.extension, SubstanceSpecification.description.extension:description, SubstanceSpecification.source, SubstanceSpecification.comment, SubstanceSpecification.moiety, SubstanceSpecification.moiety.extension, SubstanceSpecification.moiety.extension:measurementType, SubstanceSpecification.moiety.modifierExtension, SubstanceSpecification.moiety.role, SubstanceSpecification.moiety.identifier, SubstanceSpecification.moiety.name, SubstanceSpecification.moiety.stereochemistry, SubstanceSpecification.moiety.opticalActivity, SubstanceSpecification.moiety.molecularFormula, SubstanceSpecification.moiety.amount[x], SubstanceSpecification.property, SubstanceSpecification.property.extension, SubstanceSpecification.property.extension:type, SubstanceSpecification.property.extension:value, SubstanceSpecification.property.modifierExtension, SubstanceSpecification.property.category, SubstanceSpecification.property.code, SubstanceSpecification.property.parameters, SubstanceSpecification.property.definingSubstance[x], SubstanceSpecification.property.amount[x], SubstanceSpecification.referenceInformation, SubstanceSpecification.structure, SubstanceSpecification.structure.extension, SubstanceSpecification.structure.extension:technique, SubstanceSpecification.structure.extension:sourceDocument, SubstanceSpecification.structure.modifierExtension, SubstanceSpecification.structure.stereochemistry, SubstanceSpecification.structure.opticalActivity, SubstanceSpecification.structure.molecularFormula, SubstanceSpecification.structure.molecularFormulaByMoiety, SubstanceSpecification.structure.isotope, SubstanceSpecification.structure.isotope.extension, SubstanceSpecification.structure.isotope.modifierExtension, SubstanceSpecification.structure.isotope.identifier, SubstanceSpecification.structure.isotope.name, SubstanceSpecification.structure.isotope.substitution, SubstanceSpecification.structure.isotope.halfLife, SubstanceSpecification.structure.isotope.molecularWeight, SubstanceSpecification.structure.isotope.molecularWeight.extension, SubstanceSpecification.structure.isotope.molecularWeight.modifierExtension, SubstanceSpecification.structure.isotope.molecularWeight.method, SubstanceSpecification.structure.isotope.molecularWeight.type, SubstanceSpecification.structure.isotope.molecularWeight.amount, SubstanceSpecification.structure.molecularWeight, SubstanceSpecification.structure.source, SubstanceSpecification.structure.representation, SubstanceSpecification.structure.representation.extension, SubstanceSpecification.structure.representation.extension:format, SubstanceSpecification.structure.representation.extension:document, SubstanceSpecification.structure.representation.modifierExtension, SubstanceSpecification.structure.representation.type, SubstanceSpecification.structure.representation.representation, SubstanceSpecification.structure.representation.attachment, SubstanceSpecification.code, SubstanceSpecification.code.extension, SubstanceSpecification.code.extension:note, SubstanceSpecification.code.modifierExtension, SubstanceSpecification.code.code, SubstanceSpecification.code.status, SubstanceSpecification.code.statusDate, SubstanceSpecification.code.comment, SubstanceSpecification.code.source, SubstanceSpecification.code.source.extension, SubstanceSpecification.code.source.extension:source, SubstanceSpecification.code.source.reference, SubstanceSpecification.code.source.type, SubstanceSpecification.code.source.identifier, SubstanceSpecification.code.source.display, SubstanceSpecification.name, SubstanceSpecification.name.extension, SubstanceSpecification.name.extension:name, SubstanceSpecification.name.modifierExtension, SubstanceSpecification.name.name, SubstanceSpecification.name.type, SubstanceSpecification.name.status, SubstanceSpecification.name.preferred, SubstanceSpecification.name.language, SubstanceSpecification.name.language.extension, SubstanceSpecification.name.language.extension:language, SubstanceSpecification.name.language.coding, SubstanceSpecification.name.language.text, SubstanceSpecification.name.domain, SubstanceSpecification.name.jurisdiction, SubstanceSpecification.name.synonym, SubstanceSpecification.name.translation, SubstanceSpecification.name.official, SubstanceSpecification.name.official.extension, SubstanceSpecification.name.official.modifierExtension, SubstanceSpecification.name.official.authority, SubstanceSpecification.name.official.status, SubstanceSpecification.name.official.date, SubstanceSpecification.name.source, SubstanceSpecification.name.source.extension, SubstanceSpecification.name.source.extension:source, SubstanceSpecification.name.source.reference, SubstanceSpecification.name.source.type, SubstanceSpecification.name.source.identifier, SubstanceSpecification.name.source.display, SubstanceSpecification.molecularWeight, SubstanceSpecification.molecularWeight.extension, SubstanceSpecification.molecularWeight.extension:method, SubstanceSpecification.molecularWeight.extension:type, SubstanceSpecification.molecularWeight.extension:amount, SubstanceSpecification.molecularWeight.modifierExtension, SubstanceSpecification.molecularWeight.method, SubstanceSpecification.molecularWeight.type, SubstanceSpecification.molecularWeight.amount, SubstanceSpecification.relationship, SubstanceSpecification.relationship.extension, SubstanceSpecification.relationship.extension:substanceDefinition, SubstanceSpecification.relationship.extension:type, SubstanceSpecification.relationship.extension:ratioHighLimitAmount, SubstanceSpecification.relationship.extension:comparator, SubstanceSpecification.relationship.modifierExtension, SubstanceSpecification.relationship.substance[x], SubstanceSpecification.relationship.relationship, SubstanceSpecification.relationship.isDefining, SubstanceSpecification.relationship.amount[x], SubstanceSpecification.relationship.amountRatioLowLimit, SubstanceSpecification.relationship.amountType, SubstanceSpecification.relationship.source, SubstanceSpecification.relationship.source.extension, SubstanceSpecification.relationship.source.extension:source, SubstanceSpecification.relationship.source.reference, SubstanceSpecification.relationship.source.type, SubstanceSpecification.relationship.source.identifier, SubstanceSpecification.relationship.source.display, SubstanceSpecification.nucleicAcid, SubstanceSpecification.polymer, SubstanceSpecification.protein, SubstanceSpecification.sourceMaterial, SubstanceSpecification.sourceMaterial.extension, SubstanceSpecification.sourceMaterial.extension:type, SubstanceSpecification.sourceMaterial.extension:genus, SubstanceSpecification.sourceMaterial.extension:species, SubstanceSpecification.sourceMaterial.extension:part, SubstanceSpecification.sourceMaterial.extension:countryOfOrigin, SubstanceSpecification.sourceMaterial.reference, SubstanceSpecification.sourceMaterial.type, SubstanceSpecification.sourceMaterial.identifier, SubstanceSpecification.sourceMaterial.display	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	SubstanceSpecification.extension, SubstanceSpecification.extension:version, SubstanceSpecification.extension:classification, SubstanceSpecification.extension:grade, SubstanceSpecification.extension:informationSource, SubstanceSpecification.extension:note, SubstanceSpecification.extension:manufacturer, SubstanceSpecification.extension:supplier, SubstanceSpecification.extension:characterization, SubstanceSpecification.extension:referenceInformation, SubstanceSpecification.extension:nucleicAcid, SubstanceSpecification.extension:polymer, SubstanceSpecification.extension:protein, SubstanceSpecification.modifierExtension, SubstanceSpecification.identifier.extension, SubstanceSpecification.identifier.extension:identifier, SubstanceSpecification.status.extension, SubstanceSpecification.status.extension:status, SubstanceSpecification.description.extension, SubstanceSpecification.description.extension:description, SubstanceSpecification.moiety.extension, SubstanceSpecification.moiety.extension:measurementType, SubstanceSpecification.moiety.modifierExtension, SubstanceSpecification.property.extension, SubstanceSpecification.property.extension:type, SubstanceSpecification.property.extension:value, SubstanceSpecification.property.modifierExtension, SubstanceSpecification.structure.extension, SubstanceSpecification.structure.extension:technique, SubstanceSpecification.structure.extension:sourceDocument, SubstanceSpecification.structure.modifierExtension, SubstanceSpecification.structure.isotope.extension, SubstanceSpecification.structure.isotope.modifierExtension, SubstanceSpecification.structure.isotope.molecularWeight.extension, SubstanceSpecification.structure.isotope.molecularWeight.modifierExtension, SubstanceSpecification.structure.representation.extension, SubstanceSpecification.structure.representation.extension:format, SubstanceSpecification.structure.representation.extension:document, SubstanceSpecification.structure.representation.modifierExtension, SubstanceSpecification.code.extension, SubstanceSpecification.code.extension:note, SubstanceSpecification.code.modifierExtension, SubstanceSpecification.code.source.extension, SubstanceSpecification.code.source.extension:source, SubstanceSpecification.name.extension, SubstanceSpecification.name.extension:name, SubstanceSpecification.name.modifierExtension, SubstanceSpecification.name.language.extension, SubstanceSpecification.name.language.extension:language, SubstanceSpecification.name.official.extension, SubstanceSpecification.name.official.modifierExtension, SubstanceSpecification.name.source.extension, SubstanceSpecification.name.source.extension:source, SubstanceSpecification.molecularWeight.extension, SubstanceSpecification.molecularWeight.extension:method, SubstanceSpecification.molecularWeight.extension:type, SubstanceSpecification.molecularWeight.extension:amount, SubstanceSpecification.molecularWeight.modifierExtension, SubstanceSpecification.relationship.extension, SubstanceSpecification.relationship.extension:substanceDefinition, SubstanceSpecification.relationship.extension:type, SubstanceSpecification.relationship.extension:ratioHighLimitAmount, SubstanceSpecification.relationship.extension:comparator, SubstanceSpecification.relationship.modifierExtension, SubstanceSpecification.relationship.source.extension, SubstanceSpecification.relationship.source.extension:source, SubstanceSpecification.sourceMaterial.extension, SubstanceSpecification.sourceMaterial.extension:type, SubstanceSpecification.sourceMaterial.extension:genus, SubstanceSpecification.sourceMaterial.extension:species, SubstanceSpecification.sourceMaterial.extension:part, SubstanceSpecification.sourceMaterial.extension:countryOfOrigin	Must have either extensions or value[x], not both	extension.exists() != value.exists()

This structure is derived from SubstanceSpecification

Summary

Mandatory: 0 element(6 nested mandatory elements)

Extensions

This structure refers to these extensions:

• http://hl7.org/fhir/StructureDefinition/artifact-version|5.2.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.classification|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.grade|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.informationSource|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.note|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.manufacturer|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.supplier|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.characterization|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.referenceInformation|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.nucleicAcid|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.polymer|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.protein|0.1.0
• http://hl7.org/fhir/StructureDefinition/artifact-identifier|5.2.0
• http://hl7.org/fhir/StructureDefinition/artifact-status|5.2.0
• http://hl7.org/fhir/StructureDefinition/artifact-description|5.2.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.moiety.measurementType|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.type|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.value|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.technique|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.sourceDocument|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.format|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.document|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.code.note|0.1.0
• http://hl7.org/fhir/StructureDefinition/alternate-reference|5.2.0
• http://hl7.org/fhir/StructureDefinition/artifact-name|5.2.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.name.language|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.method|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.type|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.amount|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.substanceDefinition|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.type|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.ratioHighLimitAmount|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.comparator|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.type|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.genus|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.species|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.part|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.countryOfOrigin|0.1.0

Maturity: 0

Key Elements View

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
SubstanceSpecification		0..*	SubstanceSpecification(4.0.1)	The detailed description of a substance, typically at a level beyond what is used for prescribing
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:version		0..1	string	R5: A business level version identifier of the substance (new) URL: http://hl7.org/fhir/StructureDefinition/artifact-version Constraints: ext-1
extension:classification		0..*	CodeableConcept	R5: A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.classification Constraints: ext-1
extension:grade		0..*	CodeableConcept	R5: The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.grade Binding: R5SubstanceGradeForR4 (0.1.0) (example): The quality standard, established benchmark, to which a substance complies Constraints: ext-1
extension:informationSource		0..*	Reference(Cross-version Profile for R5.Citation for use in FHIR R4(0.1.0) | Basic)	R5: Supporting literature (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.informationSource Constraints: ext-1
extension:note		0..*	Annotation	R5: Textual comment about the substance's catalogue or registry record (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.note Constraints: ext-1
extension:manufacturer		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: The entity that creates, makes, produces or fabricates the substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.manufacturer Constraints: ext-1
extension:supplier		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: An entity that is the source for the substance. It may be different from the manufacturer (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.supplier Constraints: ext-1
extension:characterization		0..*	(Complex)	R5: General specifications for this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.characterization Constraints: ext-1
extension:referenceInformation		0..1	Reference(Cross-version Profile for R5.SubstanceReferenceInformation for use in FHIR R4(0.1.0) | Basic)	R5: General information detailing this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.referenceInformation Constraints: ext-1
extension:nucleicAcid		0..1	Reference(Cross-version Profile for R5.SubstanceNucleicAcid for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to nucleic acids (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.nucleicAcid Constraints: ext-1
extension:polymer		0..1	Reference(Cross-version Profile for R5.SubstancePolymer for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to polymers (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.polymer Constraints: ext-1
extension:protein		0..1	Reference(Cross-version Profile for R5.SubstanceProtein for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to proteins (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.protein Constraints: ext-1
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored Constraints: ext-1
Documentation for this format

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	SubstanceSpecification	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	SubstanceSpecification	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	SubstanceSpecification	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	SubstanceSpecification	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	SubstanceSpecification	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	SubstanceSpecification.implicitRules, SubstanceSpecification.extension, SubstanceSpecification.extension:version, SubstanceSpecification.extension:classification, SubstanceSpecification.extension:grade, SubstanceSpecification.extension:informationSource, SubstanceSpecification.extension:note, SubstanceSpecification.extension:manufacturer, SubstanceSpecification.extension:supplier, SubstanceSpecification.extension:characterization, SubstanceSpecification.extension:referenceInformation, SubstanceSpecification.extension:nucleicAcid, SubstanceSpecification.extension:polymer, SubstanceSpecification.extension:protein, SubstanceSpecification.modifierExtension	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	SubstanceSpecification.extension, SubstanceSpecification.extension:version, SubstanceSpecification.extension:classification, SubstanceSpecification.extension:grade, SubstanceSpecification.extension:informationSource, SubstanceSpecification.extension:note, SubstanceSpecification.extension:manufacturer, SubstanceSpecification.extension:supplier, SubstanceSpecification.extension:characterization, SubstanceSpecification.extension:referenceInformation, SubstanceSpecification.extension:nucleicAcid, SubstanceSpecification.extension:polymer, SubstanceSpecification.extension:protein, SubstanceSpecification.modifierExtension	Must have either extensions or value[x], not both	extension.exists() != value.exists()

Differential View

This structure is derived from SubstanceSpecification

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
SubstanceSpecification		0..*	SubstanceSpecification(4.0.1)	The detailed description of a substance, typically at a level beyond what is used for prescribing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:version		0..1	string	R5: A business level version identifier of the substance (new) URL: http://hl7.org/fhir/StructureDefinition/artifact-version
extension:classification		0..*	CodeableConcept	R5: A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.classification
extension:grade		0..*	CodeableConcept	R5: The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.grade Binding: R5SubstanceGradeForR4 (0.1.0) (example): The quality standard, established benchmark, to which a substance complies
extension:informationSource		0..*	Reference(Cross-version Profile for R5.Citation for use in FHIR R4(0.1.0) | Basic)	R5: Supporting literature (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.informationSource
extension:note		0..*	Annotation	R5: Textual comment about the substance's catalogue or registry record (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.note
extension:manufacturer		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: The entity that creates, makes, produces or fabricates the substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.manufacturer
extension:supplier		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: An entity that is the source for the substance. It may be different from the manufacturer (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.supplier
extension:characterization		0..*	(Complex)	R5: General specifications for this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.characterization
extension:referenceInformation		0..1	Reference(Cross-version Profile for R5.SubstanceReferenceInformation for use in FHIR R4(0.1.0) | Basic)	R5: General information detailing this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.referenceInformation
extension:nucleicAcid		0..1	Reference(Cross-version Profile for R5.SubstanceNucleicAcid for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to nucleic acids (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.nucleicAcid
extension:polymer		0..1	Reference(Cross-version Profile for R5.SubstancePolymer for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to polymers (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.polymer
extension:protein		0..1	Reference(Cross-version Profile for R5.SubstanceProtein for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to proteins (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.protein
identifier
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:identifier		0..*	Identifier	R5: identifier URL: http://hl7.org/fhir/StructureDefinition/artifact-identifier
status
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:status		0..1	code	R5: Status of substance within the catalogue e.g. active, retired URL: http://hl7.org/fhir/StructureDefinition/artifact-status Binding: PublicationStatus (required): The lifecycle status of an artifact.
description
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:description		0..1	markdown	R5: description URL: http://hl7.org/fhir/StructureDefinition/artifact-description
moiety
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:measurementType		0..1	CodeableConcept	R5: The measurement type of the quantitative value (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.moiety.measurementType Binding: R5SubstanceAmountTypeForR4 (0.1.0) (example): The relationship between two substance types.
property
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:type		1..1	CodeableConcept	R5: A code expressing the type of property (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.type
extension:value		0..1	CodeableConcept, Quantity, date, boolean, Attachment	R5: A value for the property (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.value
structure
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:technique		0..*	CodeableConcept	R5: The method used to find the structure e.g. X-ray, NMR (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.technique Binding: R5SubstanceStructureTechniqueForR4 (0.1.0) (example): The method used to elucidate the structure of the drug substance.
extension:sourceDocument		0..*	Reference(Cross-version Profile for R5.DocumentReference for use in FHIR R4(0.1.0) | Media)	R5: Source of information for the structure (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.sourceDocument
representation
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:format		0..1	CodeableConcept	R5: The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.format Binding: R5SubstanceRepresentationFormatForR4 (0.1.0) (example): A format of a substance representation.
extension:document		0..1	Reference(Cross-version Profile for R5.DocumentReference for use in FHIR R4(0.1.0) | Media)	R5: An attachment with the structural representation e.g. a structure graphic or AnIML file (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.document
code
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:note		0..*	Annotation	R5: Any comment can be provided in this field (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.code.note
source
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:source		0..*	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference
name
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:name		0..*	string	R5: name URL: http://hl7.org/fhir/StructureDefinition/artifact-name
language
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:language		0..*	CodeableConcept	R5: Human language that the name is written in URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.name.language
source
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:source		0..*	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference
molecularWeight
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:method		0..1	CodeableConcept	R5: The method by which the weight was determined (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.method Binding: R5SubstanceWeightMethodForR4 (0.1.0) (example): The method by which the substance weight was measured.
extension:type		0..1	CodeableConcept	R5: Type of molecular weight e.g. exact, average, weight average (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.type Binding: R5SubstanceWeightTypeForR4 (0.1.0) (example): The type of substance weight measurement.
extension:amount		1..1	Quantity	R5: Used to capture quantitative values for a variety of elements (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.amount
relationship
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:substanceDefinition		0..1	Reference(Cross-version Profile for R5.SubstanceDefinition for use in FHIR R4(0.1.0) | SubstanceSpecification), CodeableConcept	R5: A pointer to another substance, as a resource or a representational code (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.substanceDefinition
extension:type		1..1	CodeableConcept	R5: For example "salt to parent", "active moiety" (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.type Binding: R5SubstanceRelationshipTypeForR4 (0.1.0) (example): The relationship between two substance types.
extension:ratioHighLimitAmount		0..1	Ratio	R5: For use when the numeric has an uncertain range (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.ratioHighLimitAmount
extension:comparator		0..1	CodeableConcept	R5: An operator for the amount, for example "average", "approximately", "less than" (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.comparator Binding: R5SubstanceAmountTypeForR4 (0.1.0) (example): The relationship between two substance types.
source
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:source		0..*	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference
sourceMaterial
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:type		0..1	CodeableConcept	R5: Classification of the origin of the raw material. e.g. cat hair is an Animal source type (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.type Binding: R5SubstanceSourceMaterialTypeForR4 (0.1.0) (example): A classification that provides the origin of the substance raw material.
extension:genus		0..1	CodeableConcept	R5: The genus of an organism e.g. the Latin epithet of the plant/animal scientific name (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.genus Binding: R5SubstanceSourceMaterialGenusForR4 (0.1.0) (example): The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
extension:species		0..1	CodeableConcept	R5: The species of an organism e.g. the Latin epithet of the species of the plant/animal (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.species Binding: R5SubstanceSourceMaterialSpeciesForR4 (0.1.0) (example): A species of origin a substance raw material.
extension:part		0..1	CodeableConcept	R5: An anatomical origin of the source material within an organism (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.part Binding: R5SubstanceSourceMaterialPartForR4 (0.1.0) (example): An anatomical origin of the source material within an organism.
extension:countryOfOrigin		0..*	CodeableConcept	R5: The country or countries where the material is harvested (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.countryOfOrigin
Documentation for this format

Snapshot View

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
SubstanceSpecification		0..*	SubstanceSpecification(4.0.1)	The detailed description of a substance, typically at a level beyond what is used for prescribing
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:version		0..1	string	R5: A business level version identifier of the substance (new) URL: http://hl7.org/fhir/StructureDefinition/artifact-version Constraints: ext-1
extension:classification		0..*	CodeableConcept	R5: A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.classification Constraints: ext-1
extension:grade		0..*	CodeableConcept	R5: The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.grade Binding: R5SubstanceGradeForR4 (0.1.0) (example): The quality standard, established benchmark, to which a substance complies Constraints: ext-1
extension:informationSource		0..*	Reference(Cross-version Profile for R5.Citation for use in FHIR R4(0.1.0) | Basic)	R5: Supporting literature (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.informationSource Constraints: ext-1
extension:note		0..*	Annotation	R5: Textual comment about the substance's catalogue or registry record (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.note Constraints: ext-1
extension:manufacturer		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: The entity that creates, makes, produces or fabricates the substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.manufacturer Constraints: ext-1
extension:supplier		0..*	Reference(Cross-version Profile for R5.Organization for use in FHIR R4(0.1.0) | Organization)	R5: An entity that is the source for the substance. It may be different from the manufacturer (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.supplier Constraints: ext-1
extension:characterization		0..*	(Complex)	R5: General specifications for this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.characterization Constraints: ext-1
extension:referenceInformation		0..1	Reference(Cross-version Profile for R5.SubstanceReferenceInformation for use in FHIR R4(0.1.0) | Basic)	R5: General information detailing this substance (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.referenceInformation Constraints: ext-1
extension:nucleicAcid		0..1	Reference(Cross-version Profile for R5.SubstanceNucleicAcid for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to nucleic acids (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.nucleicAcid Constraints: ext-1
extension:polymer		0..1	Reference(Cross-version Profile for R5.SubstancePolymer for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to polymers (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.polymer Constraints: ext-1
extension:protein		0..1	Reference(Cross-version Profile for R5.SubstanceProtein for use in FHIR R4(0.1.0) | Basic)	R5: Data items specific to proteins (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.protein Constraints: ext-1
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored Constraints: ext-1
identifier	Σ	0..1	Identifier	Identifier by which this substance is known
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:identifier		0..*	Identifier	R5: identifier URL: http://hl7.org/fhir/StructureDefinition/artifact-identifier Constraints: ext-1
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
type	Σ	0..1	CodeableConcept	Description of identifier Binding: Identifier Type Codes (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.
system	Σ	0..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient
value	Σ	0..1	string	The value that is unique Example General: 123456
period	Σ	0..1	Period	Time period when id is/was valid for use
assigner	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)
type	Σ	0..1	CodeableConcept	High level categorization, e.g. polymer or nucleic acid
status	Σ	0..1	CodeableConcept	Status of substance within the catalogue e.g. approved
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:status		0..1	code	R5: Status of substance within the catalogue e.g. active, retired URL: http://hl7.org/fhir/StructureDefinition/artifact-status Binding: PublicationStatus (required): The lifecycle status of an artifact. Constraints: ext-1
coding	Σ	0..*	Coding	Code defined by a terminology system
text	Σ	0..1	string	Plain text representation of the concept
domain	Σ	0..1	CodeableConcept	If the substance applies to only human or veterinary use
description	Σ	0..1	string	Textual description of the substance
id		0..1	string	xml:id (or equivalent in JSON)
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:description		0..1	markdown	R5: description URL: http://hl7.org/fhir/StructureDefinition/artifact-description Constraints: ext-1
value		0..1	string	Primitive value for string Max Length:1048576
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
comment	Σ	0..1	string	Textual comment about this record of a substance
moiety	Σ	0..*	BackboneElement	Moiety, for structural modifications
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:measurementType		0..1	CodeableConcept	R5: The measurement type of the quantitative value (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.moiety.measurementType Binding: R5SubstanceAmountTypeForR4 (0.1.0) (example): The relationship between two substance types. Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
role	Σ	0..1	CodeableConcept	Role that the moiety is playing
identifier	Σ	0..1	Identifier	Identifier by which this moiety substance is known
name	Σ	0..1	string	Textual name for this moiety substance
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type
molecularFormula	Σ	0..1	string	Molecular formula
amount[x]	Σ	0..1		Quantitative value for this moiety
amountQuantity			Quantity
amountString			string
property	Σ	0..*	BackboneElement	General specifications for this substance, including how it is related to other substances
id		0..1	string	Unique id for inter-element referencing
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:type		1..1	CodeableConcept	R5: A code expressing the type of property (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.type Constraints: ext-1
extension:value		0..1	CodeableConcept, Quantity, date, boolean, Attachment	R5: A value for the property (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.value Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
category	Σ	0..1	CodeableConcept	A category for this property, e.g. Physical, Chemical, Enzymatic
code	Σ	0..1	CodeableConcept	Property type e.g. viscosity, pH, isoelectric point
parameters	Σ	0..1	string	Parameters that were used in the measurement of a property (e.g. for viscosity: measured at 20C with a pH of 7.1)
definingSubstance[x]	Σ	0..1		A substance upon which a defining property depends (e.g. for solubility: in water, in alcohol)
definingSubstanceReference			Reference(SubstanceSpecification | Substance)
definingSubstanceCodeableConcept			CodeableConcept
amount[x]	Σ	0..1		Quantitative value for this property
amountQuantity			Quantity
amountString			string
referenceInformation	Σ	0..1	Reference(SubstanceReferenceInformation)	General information detailing this substance
structure	Σ	0..1	BackboneElement	Structural information
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:technique		0..*	CodeableConcept	R5: The method used to find the structure e.g. X-ray, NMR (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.technique Binding: R5SubstanceStructureTechniqueForR4 (0.1.0) (example): The method used to elucidate the structure of the drug substance. Constraints: ext-1
extension:sourceDocument		0..*	Reference(Cross-version Profile for R5.DocumentReference for use in FHIR R4(0.1.0) | Media)	R5: Source of information for the structure (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.sourceDocument Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type
molecularFormula	Σ	0..1	string	Molecular formula
molecularFormulaByMoiety	Σ	0..1	string	Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical, each moiety separated by a dot
isotope	Σ	0..*	BackboneElement	Applicable for single substances that contain a radionuclide or a non-natural isotopic ratio
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
identifier	Σ	0..1	Identifier	Substance identifier for each non-natural or radioisotope
name	Σ	0..1	CodeableConcept	Substance name for each non-natural or radioisotope
substitution	Σ	0..1	CodeableConcept	The type of isotopic substitution present in a single substance
halfLife	Σ	0..1	Quantity	Half life - for a non-natural nuclide
molecularWeight	Σ	0..1	BackboneElement	The molecular weight or weight range (for proteins, polymers or nucleic acids)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
method	Σ	0..1	CodeableConcept	The method by which the molecular weight was determined
type	Σ	0..1	CodeableConcept	Type of molecular weight such as exact, average (also known as. number average), weight average
amount	Σ	0..1	Quantity	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field
molecularWeight	Σ	0..1	See molecularWeight (SubstanceSpecification)	The molecular weight or weight range (for proteins, polymers or nucleic acids)
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
representation	Σ	0..*	BackboneElement	Molecular structural representation
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:format		0..1	CodeableConcept	R5: The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format) (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.format Binding: R5SubstanceRepresentationFormatForR4 (0.1.0) (example): A format of a substance representation. Constraints: ext-1
extension:document		0..1	Reference(Cross-version Profile for R5.DocumentReference for use in FHIR R4(0.1.0) | Media)	R5: An attachment with the structural representation e.g. a structure graphic or AnIML file (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.document Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
type	Σ	0..1	CodeableConcept	The type of structure (e.g. Full, Partial, Representative)
representation	Σ	0..1	string	The structural representation as text string in a format e.g. InChI, SMILES, MOLFILE, CDX
attachment	Σ	0..1	Attachment	An attached file with the structural representation
code	Σ	0..*	BackboneElement	Codes associated with the substance
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:note		0..*	Annotation	R5: Any comment can be provided in this field (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.code.note Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
code	Σ	0..1	CodeableConcept	The specific code
status	Σ	0..1	CodeableConcept	Status of the code assignment
statusDate	Σ	0..1	dateTime	The date at which the code status is changed as part of the terminology maintenance
comment	Σ	0..1	string	Any comment can be provided in this field, if necessary
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:source		0..1	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference Constraints: ext-1
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	Σ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
name	Σ	0..*	BackboneElement	Names applicable to this substance
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:name		0..*	string	R5: name URL: http://hl7.org/fhir/StructureDefinition/artifact-name Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
name	Σ	1..1	string	The actual name
type	Σ	0..1	CodeableConcept	Name type
status	Σ	0..1	CodeableConcept	The status of the name
preferred	Σ	0..1	boolean	If this is the preferred name for this substance
language	Σ	0..*	CodeableConcept	Language of the name
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:language		0..*	CodeableConcept	R5: Human language that the name is written in URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.name.language Constraints: ext-1
coding	Σ	0..*	Coding	Code defined by a terminology system
text	Σ	0..1	string	Plain text representation of the concept
domain	Σ	0..*	CodeableConcept	The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive
jurisdiction	Σ	0..*	CodeableConcept	The jurisdiction where this name applies
synonym	Σ	0..*	See name (SubstanceSpecification)	A synonym of this name
translation	Σ	0..*	See name (SubstanceSpecification)	A translation for this name
official	Σ	0..*	BackboneElement	Details of the official nature of this name
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
authority	Σ	0..1	CodeableConcept	Which authority uses this official name
status	Σ	0..1	CodeableConcept	The status of the official name
date	Σ	0..1	dateTime	Date of official name change
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:source		0..1	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference Constraints: ext-1
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	Σ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
molecularWeight	Σ	0..*	BackboneElement	The molecular weight or weight range (for proteins, polymers or nucleic acids)
id		0..1	string	Unique id for inter-element referencing
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:method		0..1	CodeableConcept	R5: The method by which the weight was determined (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.method Binding: R5SubstanceWeightMethodForR4 (0.1.0) (example): The method by which the substance weight was measured. Constraints: ext-1
extension:type		0..1	CodeableConcept	R5: Type of molecular weight e.g. exact, average, weight average (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.type Binding: R5SubstanceWeightTypeForR4 (0.1.0) (example): The type of substance weight measurement. Constraints: ext-1
extension:amount		1..1	Quantity	R5: Used to capture quantitative values for a variety of elements (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.amount Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
method	Σ	0..1	CodeableConcept	The method by which the molecular weight was determined
type	Σ	0..1	CodeableConcept	Type of molecular weight such as exact, average (also known as. number average), weight average
amount	Σ	0..1	Quantity	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field
relationship	Σ	0..*	BackboneElement	A link between this substance and another, with details of the relationship
id		0..1	string	Unique id for inter-element referencing
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:substanceDefinition		0..1	Reference(Cross-version Profile for R5.SubstanceDefinition for use in FHIR R4(0.1.0) | SubstanceSpecification), CodeableConcept	R5: A pointer to another substance, as a resource or a representational code (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.substanceDefinition Constraints: ext-1
extension:type		1..1	CodeableConcept	R5: For example "salt to parent", "active moiety" (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.type Binding: R5SubstanceRelationshipTypeForR4 (0.1.0) (example): The relationship between two substance types. Constraints: ext-1
extension:ratioHighLimitAmount		0..1	Ratio	R5: For use when the numeric has an uncertain range (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.ratioHighLimitAmount Constraints: ext-1
extension:comparator		0..1	CodeableConcept	R5: An operator for the amount, for example "average", "approximately", "less than" (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.comparator Binding: R5SubstanceAmountTypeForR4 (0.1.0) (example): The relationship between two substance types. Constraints: ext-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized Constraints: ext-1
substance[x]	Σ	0..1		A pointer to another substance, as a resource or just a representational code
substanceReference			Reference(SubstanceSpecification)
substanceCodeableConcept			CodeableConcept
relationship	Σ	0..1	CodeableConcept	For example "salt to parent", "active moiety", "starting material"
isDefining	Σ	0..1	boolean	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible substance relationships
amount[x]	Σ	0..1		A numeric factor for the relationship, for instance to express that the salt of a substance has some percentage of the active substance in relation to some other
amountQuantity			Quantity
amountRange			Range
amountRatio			Ratio
amountString			string
amountRatioLowLimit	Σ	0..1	Ratio	For use when the numeric
amountType	Σ	0..1	CodeableConcept	An operator for the amount, for example "average", "approximately", "less than"
source	Σ	0..*	Reference(DocumentReference)	Supporting literature
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:source		0..1	Reference(Resource)	R5: source additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference Constraints: ext-1
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	Σ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
nucleicAcid	Σ	0..1	Reference(SubstanceNucleicAcid)	Data items specific to nucleic acids
polymer	Σ	0..1	Reference(SubstancePolymer)	Data items specific to polymers
protein	Σ	0..1	Reference(SubstanceProtein)	Data items specific to proteins
sourceMaterial	Σ	0..1	Reference(SubstanceSourceMaterial)	Material or taxonomic/anatomical source for the substance
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Constraints: ext-1
extension:type		0..1	CodeableConcept	R5: Classification of the origin of the raw material. e.g. cat hair is an Animal source type (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.type Binding: R5SubstanceSourceMaterialTypeForR4 (0.1.0) (example): A classification that provides the origin of the substance raw material. Constraints: ext-1
extension:genus		0..1	CodeableConcept	R5: The genus of an organism e.g. the Latin epithet of the plant/animal scientific name (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.genus Binding: R5SubstanceSourceMaterialGenusForR4 (0.1.0) (example): The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name. Constraints: ext-1
extension:species		0..1	CodeableConcept	R5: The species of an organism e.g. the Latin epithet of the species of the plant/animal (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.species Binding: R5SubstanceSourceMaterialSpeciesForR4 (0.1.0) (example): A species of origin a substance raw material. Constraints: ext-1
extension:part		0..1	CodeableConcept	R5: An anatomical origin of the source material within an organism (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.part Binding: R5SubstanceSourceMaterialPartForR4 (0.1.0) (example): An anatomical origin of the source material within an organism. Constraints: ext-1
extension:countryOfOrigin		0..*	CodeableConcept	R5: The country or countries where the material is harvested (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.countryOfOrigin Constraints: ext-1
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	Σ	0..1	Identifier	Logical reference, when literal reference is not known
display	Σ	0..1	string	Text alternative for the resource
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
SubstanceSpecification.​language	Base	preferred	Common Languages	📍4.0.1	tx.fhir.org
SubstanceSpecification.​identifier.use	Base	required	IdentifierUse	📍4.0.1	FHIR Std.
SubstanceSpecification.​identifier.type	Base	extensible	IdentifierType	📍4.0.1	FHIR Std.
SubstanceSpecification.​code.source.type	Base	extensible	ResourceType	📍4.0.1	tx.fhir.org
SubstanceSpecification.​name.source.type	Base	extensible	ResourceType	📍4.0.1	tx.fhir.org
SubstanceSpecification.​relationship.source.​type	Base	extensible	ResourceType	📍4.0.1	tx.fhir.org
SubstanceSpecification.​sourceMaterial.type	Base	extensible	ResourceType	📍4.0.1	tx.fhir.org

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	SubstanceSpecification	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	SubstanceSpecification	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	SubstanceSpecification	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	SubstanceSpecification	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	SubstanceSpecification	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	SubstanceSpecification.meta, SubstanceSpecification.implicitRules, SubstanceSpecification.language, SubstanceSpecification.text, SubstanceSpecification.extension, SubstanceSpecification.extension:version, SubstanceSpecification.extension:classification, SubstanceSpecification.extension:grade, SubstanceSpecification.extension:informationSource, SubstanceSpecification.extension:note, SubstanceSpecification.extension:manufacturer, SubstanceSpecification.extension:supplier, SubstanceSpecification.extension:characterization, SubstanceSpecification.extension:referenceInformation, SubstanceSpecification.extension:nucleicAcid, SubstanceSpecification.extension:polymer, SubstanceSpecification.extension:protein, SubstanceSpecification.modifierExtension, SubstanceSpecification.identifier, SubstanceSpecification.identifier.extension, SubstanceSpecification.identifier.extension:identifier, SubstanceSpecification.identifier.use, SubstanceSpecification.identifier.type, SubstanceSpecification.identifier.system, SubstanceSpecification.identifier.value, SubstanceSpecification.identifier.period, SubstanceSpecification.identifier.assigner, SubstanceSpecification.type, SubstanceSpecification.status, SubstanceSpecification.status.extension, SubstanceSpecification.status.extension:status, SubstanceSpecification.status.coding, SubstanceSpecification.status.text, SubstanceSpecification.domain, SubstanceSpecification.description, SubstanceSpecification.description.extension, SubstanceSpecification.description.extension:description, SubstanceSpecification.source, SubstanceSpecification.comment, SubstanceSpecification.moiety, SubstanceSpecification.moiety.extension, SubstanceSpecification.moiety.extension:measurementType, SubstanceSpecification.moiety.modifierExtension, SubstanceSpecification.moiety.role, SubstanceSpecification.moiety.identifier, SubstanceSpecification.moiety.name, SubstanceSpecification.moiety.stereochemistry, SubstanceSpecification.moiety.opticalActivity, SubstanceSpecification.moiety.molecularFormula, SubstanceSpecification.moiety.amount[x], SubstanceSpecification.property, SubstanceSpecification.property.extension, SubstanceSpecification.property.extension:type, SubstanceSpecification.property.extension:value, SubstanceSpecification.property.modifierExtension, SubstanceSpecification.property.category, SubstanceSpecification.property.code, SubstanceSpecification.property.parameters, SubstanceSpecification.property.definingSubstance[x], SubstanceSpecification.property.amount[x], SubstanceSpecification.referenceInformation, SubstanceSpecification.structure, SubstanceSpecification.structure.extension, SubstanceSpecification.structure.extension:technique, SubstanceSpecification.structure.extension:sourceDocument, SubstanceSpecification.structure.modifierExtension, SubstanceSpecification.structure.stereochemistry, SubstanceSpecification.structure.opticalActivity, SubstanceSpecification.structure.molecularFormula, SubstanceSpecification.structure.molecularFormulaByMoiety, SubstanceSpecification.structure.isotope, SubstanceSpecification.structure.isotope.extension, SubstanceSpecification.structure.isotope.modifierExtension, SubstanceSpecification.structure.isotope.identifier, SubstanceSpecification.structure.isotope.name, SubstanceSpecification.structure.isotope.substitution, SubstanceSpecification.structure.isotope.halfLife, SubstanceSpecification.structure.isotope.molecularWeight, SubstanceSpecification.structure.isotope.molecularWeight.extension, SubstanceSpecification.structure.isotope.molecularWeight.modifierExtension, SubstanceSpecification.structure.isotope.molecularWeight.method, SubstanceSpecification.structure.isotope.molecularWeight.type, SubstanceSpecification.structure.isotope.molecularWeight.amount, SubstanceSpecification.structure.molecularWeight, SubstanceSpecification.structure.source, SubstanceSpecification.structure.representation, SubstanceSpecification.structure.representation.extension, SubstanceSpecification.structure.representation.extension:format, SubstanceSpecification.structure.representation.extension:document, SubstanceSpecification.structure.representation.modifierExtension, SubstanceSpecification.structure.representation.type, SubstanceSpecification.structure.representation.representation, SubstanceSpecification.structure.representation.attachment, SubstanceSpecification.code, SubstanceSpecification.code.extension, SubstanceSpecification.code.extension:note, SubstanceSpecification.code.modifierExtension, SubstanceSpecification.code.code, SubstanceSpecification.code.status, SubstanceSpecification.code.statusDate, SubstanceSpecification.code.comment, SubstanceSpecification.code.source, SubstanceSpecification.code.source.extension, SubstanceSpecification.code.source.extension:source, SubstanceSpecification.code.source.reference, SubstanceSpecification.code.source.type, SubstanceSpecification.code.source.identifier, SubstanceSpecification.code.source.display, SubstanceSpecification.name, SubstanceSpecification.name.extension, SubstanceSpecification.name.extension:name, SubstanceSpecification.name.modifierExtension, SubstanceSpecification.name.name, SubstanceSpecification.name.type, SubstanceSpecification.name.status, SubstanceSpecification.name.preferred, SubstanceSpecification.name.language, SubstanceSpecification.name.language.extension, SubstanceSpecification.name.language.extension:language, SubstanceSpecification.name.language.coding, SubstanceSpecification.name.language.text, SubstanceSpecification.name.domain, SubstanceSpecification.name.jurisdiction, SubstanceSpecification.name.synonym, SubstanceSpecification.name.translation, SubstanceSpecification.name.official, SubstanceSpecification.name.official.extension, SubstanceSpecification.name.official.modifierExtension, SubstanceSpecification.name.official.authority, SubstanceSpecification.name.official.status, SubstanceSpecification.name.official.date, SubstanceSpecification.name.source, SubstanceSpecification.name.source.extension, SubstanceSpecification.name.source.extension:source, SubstanceSpecification.name.source.reference, SubstanceSpecification.name.source.type, SubstanceSpecification.name.source.identifier, SubstanceSpecification.name.source.display, SubstanceSpecification.molecularWeight, SubstanceSpecification.molecularWeight.extension, SubstanceSpecification.molecularWeight.extension:method, SubstanceSpecification.molecularWeight.extension:type, SubstanceSpecification.molecularWeight.extension:amount, SubstanceSpecification.molecularWeight.modifierExtension, SubstanceSpecification.molecularWeight.method, SubstanceSpecification.molecularWeight.type, SubstanceSpecification.molecularWeight.amount, SubstanceSpecification.relationship, SubstanceSpecification.relationship.extension, SubstanceSpecification.relationship.extension:substanceDefinition, SubstanceSpecification.relationship.extension:type, SubstanceSpecification.relationship.extension:ratioHighLimitAmount, SubstanceSpecification.relationship.extension:comparator, SubstanceSpecification.relationship.modifierExtension, SubstanceSpecification.relationship.substance[x], SubstanceSpecification.relationship.relationship, SubstanceSpecification.relationship.isDefining, SubstanceSpecification.relationship.amount[x], SubstanceSpecification.relationship.amountRatioLowLimit, SubstanceSpecification.relationship.amountType, SubstanceSpecification.relationship.source, SubstanceSpecification.relationship.source.extension, SubstanceSpecification.relationship.source.extension:source, SubstanceSpecification.relationship.source.reference, SubstanceSpecification.relationship.source.type, SubstanceSpecification.relationship.source.identifier, SubstanceSpecification.relationship.source.display, SubstanceSpecification.nucleicAcid, SubstanceSpecification.polymer, SubstanceSpecification.protein, SubstanceSpecification.sourceMaterial, SubstanceSpecification.sourceMaterial.extension, SubstanceSpecification.sourceMaterial.extension:type, SubstanceSpecification.sourceMaterial.extension:genus, SubstanceSpecification.sourceMaterial.extension:species, SubstanceSpecification.sourceMaterial.extension:part, SubstanceSpecification.sourceMaterial.extension:countryOfOrigin, SubstanceSpecification.sourceMaterial.reference, SubstanceSpecification.sourceMaterial.type, SubstanceSpecification.sourceMaterial.identifier, SubstanceSpecification.sourceMaterial.display	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	SubstanceSpecification.extension, SubstanceSpecification.extension:version, SubstanceSpecification.extension:classification, SubstanceSpecification.extension:grade, SubstanceSpecification.extension:informationSource, SubstanceSpecification.extension:note, SubstanceSpecification.extension:manufacturer, SubstanceSpecification.extension:supplier, SubstanceSpecification.extension:characterization, SubstanceSpecification.extension:referenceInformation, SubstanceSpecification.extension:nucleicAcid, SubstanceSpecification.extension:polymer, SubstanceSpecification.extension:protein, SubstanceSpecification.modifierExtension, SubstanceSpecification.identifier.extension, SubstanceSpecification.identifier.extension:identifier, SubstanceSpecification.status.extension, SubstanceSpecification.status.extension:status, SubstanceSpecification.description.extension, SubstanceSpecification.description.extension:description, SubstanceSpecification.moiety.extension, SubstanceSpecification.moiety.extension:measurementType, SubstanceSpecification.moiety.modifierExtension, SubstanceSpecification.property.extension, SubstanceSpecification.property.extension:type, SubstanceSpecification.property.extension:value, SubstanceSpecification.property.modifierExtension, SubstanceSpecification.structure.extension, SubstanceSpecification.structure.extension:technique, SubstanceSpecification.structure.extension:sourceDocument, SubstanceSpecification.structure.modifierExtension, SubstanceSpecification.structure.isotope.extension, SubstanceSpecification.structure.isotope.modifierExtension, SubstanceSpecification.structure.isotope.molecularWeight.extension, SubstanceSpecification.structure.isotope.molecularWeight.modifierExtension, SubstanceSpecification.structure.representation.extension, SubstanceSpecification.structure.representation.extension:format, SubstanceSpecification.structure.representation.extension:document, SubstanceSpecification.structure.representation.modifierExtension, SubstanceSpecification.code.extension, SubstanceSpecification.code.extension:note, SubstanceSpecification.code.modifierExtension, SubstanceSpecification.code.source.extension, SubstanceSpecification.code.source.extension:source, SubstanceSpecification.name.extension, SubstanceSpecification.name.extension:name, SubstanceSpecification.name.modifierExtension, SubstanceSpecification.name.language.extension, SubstanceSpecification.name.language.extension:language, SubstanceSpecification.name.official.extension, SubstanceSpecification.name.official.modifierExtension, SubstanceSpecification.name.source.extension, SubstanceSpecification.name.source.extension:source, SubstanceSpecification.molecularWeight.extension, SubstanceSpecification.molecularWeight.extension:method, SubstanceSpecification.molecularWeight.extension:type, SubstanceSpecification.molecularWeight.extension:amount, SubstanceSpecification.molecularWeight.modifierExtension, SubstanceSpecification.relationship.extension, SubstanceSpecification.relationship.extension:substanceDefinition, SubstanceSpecification.relationship.extension:type, SubstanceSpecification.relationship.extension:ratioHighLimitAmount, SubstanceSpecification.relationship.extension:comparator, SubstanceSpecification.relationship.modifierExtension, SubstanceSpecification.relationship.source.extension, SubstanceSpecification.relationship.source.extension:source, SubstanceSpecification.sourceMaterial.extension, SubstanceSpecification.sourceMaterial.extension:type, SubstanceSpecification.sourceMaterial.extension:genus, SubstanceSpecification.sourceMaterial.extension:species, SubstanceSpecification.sourceMaterial.extension:part, SubstanceSpecification.sourceMaterial.extension:countryOfOrigin	Must have either extensions or value[x], not both	extension.exists() != value.exists()

This structure is derived from SubstanceSpecification

Summary

Mandatory: 0 element(6 nested mandatory elements)

Extensions

This structure refers to these extensions:

• http://hl7.org/fhir/StructureDefinition/artifact-version|5.2.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.classification|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.grade|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.informationSource|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.note|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.manufacturer|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.supplier|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.characterization|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.referenceInformation|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.nucleicAcid|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.polymer|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.protein|0.1.0
• http://hl7.org/fhir/StructureDefinition/artifact-identifier|5.2.0
• http://hl7.org/fhir/StructureDefinition/artifact-status|5.2.0
• http://hl7.org/fhir/StructureDefinition/artifact-description|5.2.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.moiety.measurementType|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.type|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.property.value|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.technique|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.sourceDocument|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.format|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.structure.representation.document|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.code.note|0.1.0
• http://hl7.org/fhir/StructureDefinition/alternate-reference|5.2.0
• http://hl7.org/fhir/StructureDefinition/artifact-name|5.2.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.name.language|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.method|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.type|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.molecularWeight.amount|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.substanceDefinition|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.type|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.ratioHighLimitAmount|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.relationship.comparator|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.type|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.genus|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.species|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.part|0.1.0
• http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition.sourceMaterial.countryOfOrigin|0.1.0

Maturity: 0