Potential Drug-Drug Interaction (PDDI) CDS IG : STU1 Ballot 2
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: observation-digoxin-cyclosporine-renal - JSON Representation

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{
  "resourceType" : "Observation",
  "id" : "observation-digoxin-cyclosporine-renal",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"observation-digoxin-cyclosporine-renal\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;observation-digoxin-cyclosporine-renal&quot; </p></div><p><b>status</b>: final</p><p><b>code</b>: Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#33914-3)</span></p><p><b>subject</b>: <a href=\"Patient-patient-digoxin-cyclosporine-context.html\">Patient/patient-digoxin-cyclosporine-context</a></p><p><b>issued</b>: Jul 4, 2018 1:34:00 PM</p><p><b>method</b>: MDRD <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#702668005)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Glomerular filtration rate/1.73 sq M.predicted among blacks [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#48643-1)</span></p><p><b>value</b>: &gt;60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></p><h3>ReferenceRanges</h3><table class=\"grid\"><tr><td>-</td><td><b>Low</b></td><td><b>AppliesTo</b></td><td><b>Age</b></td></tr><tr><td>*</td><td>60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></td><td>non-black/african-american <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>18-? yrs</td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glomerular filtration rate/1.73 sq M.predicted among non-blacks [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#48642-3)</span></p><p><b>value</b>: 60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></p><h3>ReferenceRanges</h3><table class=\"grid\"><tr><td>-</td><td><b>Low</b></td><td><b>Age</b></td></tr><tr><td>*</td><td>60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></td><td>18-? yrs</td></tr></table></blockquote></div>"
  },
  "status" : "final",
  "code" : {
    "coding" : [
      {
        "system" : "http://loinc.org",
        "code" : "33914-3",
        "display" : "Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD)"
      }
    ]
  },
  "subject" : {
    "reference" : "Patient/patient-digoxin-cyclosporine-context"
  },
  "issued" : "2018-07-04T14:34:00+01:00",
  "method" : {
    "coding" : [
      {
        "system" : "http://snomed.info/sct",
        "code" : "702668005",
        "display" : "MDRD"
      }
    ]
  },
  "component" : [
    {
      "code" : {
        "coding" : [
          {
            "system" : "http://loinc.org",
            "code" : "48643-1",
            "display" : "Glomerular filtration rate/1.73 sq M.predicted among blacks [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)"
          }
        ]
      },
      "valueQuantity" : {
        "value" : 60,
        "comparator" : ">",
        "unit" : "mL/min/1.73m2",
        "system" : "http://unitsofmeasure.org",
        "code" : "mL/min/{1.73_m2}"
      },
      "referenceRange" : [
        {
          "low" : {
            "value" : 60,
            "unit" : "mL/min/1.73m2",
            "system" : "http://unitsofmeasure.org",
            "code" : "mL/min/{1.73_m2}"
          },
          "appliesTo" : [
            {
              "text" : "non-black/african-american"
            }
          ],
          "age" : {
            "low" : {
              "value" : 18,
              "unit" : "yrs",
              "system" : "http://unitsofmeasure.org",
              "code" : "a"
            }
          }
        }
      ]
    },
    {
      "code" : {
        "coding" : [
          {
            "system" : "http://loinc.org",
            "code" : "48642-3",
            "display" : "Glomerular filtration rate/1.73 sq M.predicted among non-blacks [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)"
          }
        ]
      },
      "valueQuantity" : {
        "value" : 60,
        "unit" : "mL/min/1.73m2",
        "system" : "http://unitsofmeasure.org",
        "code" : "mL/min/{1.73_m2}"
      },
      "referenceRange" : [
        {
          "low" : {
            "value" : 60,
            "unit" : "mL/min/1.73m2",
            "system" : "http://unitsofmeasure.org",
            "code" : "mL/min/{1.73_m2}"
          },
          "age" : {
            "low" : {
              "value" : 18,
              "unit" : "yrs",
              "system" : "http://unitsofmeasure.org",
              "code" : "a"
            }
          }
        }
      ]
    }
  ]
}