Potential Drug-Drug Interaction (PDDI) CDS IG : STU1 Ballot 2
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This page is part of the Potential Drug-Drug Interaction (PDDI) Clinical Decision Support (CDS) (FHIR IG) (v1.0.0-ballot: STU 1 Ballot 3) based on FHIR R4. . For a full list of available versions, see the Directory of published versions

: observation-digoxin-cyclosporine-renal - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Observation;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "observation-digoxin-cyclosporine-renal"]; # 
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Observation</b><a name=\"observation-digoxin-cyclosporine-renal\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Observation &quot;observation-digoxin-cyclosporine-renal&quot; </p></div><p><b>status</b>: final</p><p><b>code</b>: Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#33914-3)</span></p><p><b>subject</b>: <a href=\"Patient-patient-digoxin-cyclosporine-context.html\">Patient/patient-digoxin-cyclosporine-context</a></p><p><b>issued</b>: Jul 4, 2018 1:34:00 PM</p><p><b>method</b>: MDRD <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#702668005)</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Glomerular filtration rate/1.73 sq M.predicted among blacks [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#48643-1)</span></p><p><b>value</b>: &gt;60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></p><h3>ReferenceRanges</h3><table class=\"grid\"><tr><td>-</td><td><b>Low</b></td><td><b>AppliesTo</b></td><td><b>Age</b></td></tr><tr><td>*</td><td>60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></td><td>non-black/african-american <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>18-? yrs</td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glomerular filtration rate/1.73 sq M.predicted among non-blacks [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#48642-3)</span></p><p><b>value</b>: 60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></p><h3>ReferenceRanges</h3><table class=\"grid\"><tr><td>-</td><td><b>Low</b></td><td><b>Age</b></td></tr><tr><td>*</td><td>60 mL/min/1.73m2<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></td><td>18-? yrs</td></tr></table></blockquote></div>"
  ]; # 
  fhir:Observation.status [ fhir:value "final"]; # 
  fhir:Observation.code [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       a loinc:33914-3;
       fhir:Coding.system [ fhir:value "http://loinc.org" ];
       fhir:Coding.code [ fhir:value "33914-3" ];
       fhir:Coding.display [ fhir:value "Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD)" ]     ]
  ]; # 
  fhir:Observation.subject [
     fhir:Reference.reference [ fhir:value "Patient/patient-digoxin-cyclosporine-context" ]
  ]; # 
  fhir:Observation.issued [ fhir:value "2018-07-04T14:34:00+01:00"^^xsd:dateTime]; # 
  fhir:Observation.method [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       a sct:702668005;
       fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
       fhir:Coding.code [ fhir:value "702668005" ];
       fhir:Coding.display [ fhir:value "MDRD" ]     ]
  ]; # 
  fhir:Observation.component [
     fhir:index 0;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a loinc:48643-1;
         fhir:Coding.system [ fhir:value "http://loinc.org" ];
         fhir:Coding.code [ fhir:value "48643-1" ];
         fhir:Coding.display [ fhir:value "Glomerular filtration rate/1.73 sq M.predicted among blacks [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)" ]       ]     ];
     fhir:Observation.component.valueQuantity [
       fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
       fhir:Quantity.comparator [ fhir:value ">" ];
       fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]     ];
     fhir:Observation.component.referenceRange [
       fhir:index 0;
       fhir:Observation.referenceRange.low [
         fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
         fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]       ];
       fhir:Observation.referenceRange.appliesTo [
         fhir:index 0;
         fhir:CodeableConcept.text [ fhir:value "non-black/african-american" ]       ];
       fhir:Observation.referenceRange.age [
         fhir:Range.low [
           fhir:Quantity.value [ fhir:value "18"^^xsd:decimal ];
           fhir:Quantity.unit [ fhir:value "yrs" ];
           fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
           fhir:Quantity.code [ fhir:value "a" ]         ]       ]     ]
  ], [
     fhir:index 1;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a loinc:48642-3;
         fhir:Coding.system [ fhir:value "http://loinc.org" ];
         fhir:Coding.code [ fhir:value "48642-3" ];
         fhir:Coding.display [ fhir:value "Glomerular filtration rate/1.73 sq M.predicted among non-blacks [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)" ]       ]     ];
     fhir:Observation.component.valueQuantity [
       fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
       fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]     ];
     fhir:Observation.component.referenceRange [
       fhir:index 0;
       fhir:Observation.referenceRange.low [
         fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
         fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]       ];
       fhir:Observation.referenceRange.age [
         fhir:Range.low [
           fhir:Quantity.value [ fhir:value "18"^^xsd:decimal ];
           fhir:Quantity.unit [ fhir:value "yrs" ];
           fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
           fhir:Quantity.code [ fhir:value "a" ]         ]       ]     ]
  ]. # 

# - ontology header ------------------------------------------------------------

 a owl:Ontology;
  owl:imports fhir:fhir.ttl.