ICHOM FHIR Implementation Guide: Breast Cancer
1.0.0-ballot - ballot International flag

This page is part of the ICHOM FHIR Implementation Guide: Breast Cancer (v1.0.0-ballot: STU 1 Ballot 1) based on FHIR R4. . For a full list of available versions, see the Directory of published versions

: Bundle the clinical response at baseline - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Bundle;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "DebugBundleClinical-01-Baseline"]; # 
  fhir:Bundle.type [ fhir:value "transaction"]; # 
  fhir:Bundle.entry [
     fhir:index 0;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "LateralityVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"LateralityVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;LateralityVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: LateralityVS</p><p><b>title</b>: Laterality of breast cancer ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the laterality of breast cancer</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 80248007</p><p><b>display</b>: Left breast structure</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 73056007</p><p><b>display</b>: Right breast structure</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 63762007</p><p><b>display</b>: Both breasts</p></blockquote></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "LateralityVS" ];
       fhir:ValueSet.title [ fhir:value "Laterality of breast cancer ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the laterality of breast cancer" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "80248007" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Left breast structure" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "73056007" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Right breast structure" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "63762007" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Both breasts" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/LateralityVS" ]     ]
  ], [
     fhir:index 1;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "NoYesUnknownVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"NoYesUnknownVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;NoYesUnknownVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: NoYesUnknownVS</p><p><b>title</b>: Yes, No and Unknown Valueset</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset with yes, no and unknown answers</p><p><b>copyright</b>: Copyright HL7. Licensed under creative commons public domain</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v2-0532.html\">expandedYes-NoIndicator</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: Y</p><p><b>display</b>: Yes</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: N</p><p><b>display</b>: No</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: UNK</p><p><b>display</b>: Unknown</p></blockquote></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "NoYesUnknownVS" ];
       fhir:ValueSet.title [ fhir:value "Yes, No and Unknown Valueset" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset with yes, no and unknown answers" ];
       fhir:ValueSet.copyright [ fhir:value "Copyright HL7. Licensed under creative commons public domain" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v2-0532" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "Y" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Yes" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "N" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "No" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "UNK" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Unknown" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/NoYesUnknownVS" ]     ]
  ], [
     fhir:index 2;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "LateralityNewCancerVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"LateralityNewCancerVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;LateralityNewCancerVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityNewCancerVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: LateralityNewCancerVS</p><p><b>title</b>: Laterality of new cancer ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the laterality of new breast cancer</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 255208005</p><p><b>display</b>: Ipsilateral</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 255209002</p><p><b>display</b>: Contralateral</p></blockquote></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityNewCancerVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "LateralityNewCancerVS" ];
       fhir:ValueSet.title [ fhir:value "Laterality of new cancer ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the laterality of new breast cancer" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "255208005" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Ipsilateral" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "255209002" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Contralateral" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/LateralityNewCancerVS" ]     ]
  ], [
     fhir:index 3;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "HistologicalTypeVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"HistologicalTypeVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;HistologicalTypeVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HistologicalTypeVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: HistologicalTypeVS</p><p><b>title</b>: Histological type of the tumor ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the histological types of tumors</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 399935008</p><p><b>display</b>: Ductal carcinoma in situ - category</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 373395001</p><p><b>display</b>: Invasive ductal carcinoma with an extensive intraductal component</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 722524005</p><p><b>display</b>: Primary invasive pleomorphic lobular carcinoma of breast</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: OTH</p><p><b>display</b>: other</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: UNK</p><p><b>display</b>: unknown</p></blockquote></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HistologicalTypeVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "HistologicalTypeVS" ];
       fhir:ValueSet.title [ fhir:value "Histological type of the tumor ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the histological types of tumors" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "399935008" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Ductal carcinoma in situ - category" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "373395001" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Invasive ductal carcinoma with an extensive intraductal component" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "722524005" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Primary invasive pleomorphic lobular carcinoma of breast" ]           ]         ], [
           fhir:index 1;
           fhir:ValueSet.compose.include.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-NullFlavor" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "OTH" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "other" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "UNK" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "unknown" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/HistologicalTypeVS" ]     ]
  ], [
     fhir:index 4;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "GermlineMutationVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"GermlineMutationVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;GermlineMutationVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GermlineMutationVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: GermlineMutationVS</p><p><b>title</b>: Germline Mutation ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the genetic mutation predisposing breast cancer</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 445180002</p><p><b>display</b>: Breast cancer genetic marker of susceptibility negative (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 412734009</p><p><b>display</b>: BRCA1 gene mutation positive (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 412738007</p><p><b>display</b>: BRCA2 gene mutation positive (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416237000</p><p><b>display</b>: Procedure not done</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>OTH</td><td>other</td></tr></table></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GermlineMutationVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "GermlineMutationVS" ];
       fhir:ValueSet.title [ fhir:value "Germline Mutation ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the genetic mutation predisposing breast cancer" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "445180002" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Breast cancer genetic marker of susceptibility negative (finding)" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "412734009" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "BRCA1 gene mutation positive (finding)" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "412738007" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "BRCA2 gene mutation positive (finding)" ]           ], [
             fhir:index 3;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "416237000" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Procedure not done" ]           ]         ], [
           fhir:index 1;
           fhir:ValueSet.compose.include.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-NullFlavor" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "OTH" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "other" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/GermlineMutationVS" ]     ]
  ], [
     fhir:index 5;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "GradingVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"GradingVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;GradingVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: GradingVS</p><p><b>title</b>: Grading of tumor ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the grade of the tumor</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 399415002</p><p><b>display</b>: Low grade histologic differentiation (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 405986005</p><p><b>display</b>: Intermediate grade histologic differentiation (finding)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 399611001</p><p><b>display</b>: High grade histologic differentiation (finding)</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>NI</td><td>No information</td></tr></table></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "GradingVS" ];
       fhir:ValueSet.title [ fhir:value "Grading of tumor ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the grade of the tumor" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "399415002" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Low grade histologic differentiation (finding)" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "405986005" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Intermediate grade histologic differentiation (finding)" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "399611001" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "High grade histologic differentiation (finding)" ]           ]         ], [
           fhir:index 1;
           fhir:ValueSet.compose.include.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-NullFlavor" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "NI" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "No information" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/GradingVS" ]     ]
  ], [
     fhir:index 6;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "TNMPrimaryTumorVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"TNMPrimaryTumorVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;TNMPrimaryTumorVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMPrimaryTumorVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: TNMPrimaryTumorVS</p><p><b>title</b>: TNM Primary Tumor ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the TNM stage for the T category, according to TNM staging rules</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 1222604002</p><p><b>display</b>: American Joint Committee on Cancer cTX</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228882005</p><p><b>display</b>: American Joint Committee on Cancer cT0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228885007</p><p><b>display</b>: American Joint Committee on Cancer cTis(DCIS)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228888009</p><p><b>display</b>: American Joint Committee on Cancer cTis(Paget)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228889001</p><p><b>display</b>: American Joint Committee on Cancer cT1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228929004</p><p><b>display</b>: American Joint Committee on Cancer cT2</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228938002</p><p><b>display</b>: American Joint Committee on Cancer cT3</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228944003</p><p><b>display</b>: American Joint Committee on Cancer cT4</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228950008</p><p><b>display</b>: American Joint Committee on Cancer pTX</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228951007</p><p><b>display</b>: American Joint Committee on Cancer pT0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228954004</p><p><b>display</b>: American Joint Committee on Cancer pTis(DCIS)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228956002</p><p><b>display</b>: American Joint Committee on Cancer pTis(Paget)</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1228957006</p><p><b>display</b>: American Joint Committee on Cancer pT1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229852009</p><p><b>display</b>: American Joint Committee on Cancer pT2</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229859000</p><p><b>display</b>: American Joint Committee on Cancer pT3</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229864001</p><p><b>display</b>: American Joint Committee on Cancer pT4</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMPrimaryTumorVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "TNMPrimaryTumorVS" ];
       fhir:ValueSet.title [ fhir:value "TNM Primary Tumor ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the TNM stage for the T category, according to TNM staging rules" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1222604002" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cTX" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228882005" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cT0" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228885007" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cTis(DCIS)" ]           ], [
             fhir:index 3;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228888009" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cTis(Paget)" ]           ], [
             fhir:index 4;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228889001" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cT1" ]           ], [
             fhir:index 5;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228929004" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cT2" ]           ], [
             fhir:index 6;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228938002" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cT3" ]           ], [
             fhir:index 7;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228944003" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cT4" ]           ], [
             fhir:index 8;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228950008" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pTX" ]           ], [
             fhir:index 9;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228951007" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pT0" ]           ], [
             fhir:index 10;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228954004" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pTis(DCIS)" ]           ], [
             fhir:index 11;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228956002" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pTis(Paget)" ]           ], [
             fhir:index 12;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1228957006" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pT1" ]           ], [
             fhir:index 13;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229852009" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pT2" ]           ], [
             fhir:index 14;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229859000" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pT3" ]           ], [
             fhir:index 15;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229864001" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pT4" ]           ]         ], [
           fhir:index 1;
           fhir:ValueSet.compose.include.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-NullFlavor" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "UNK" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "unknown" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/TNMPrimaryTumorVS" ]     ]
  ], [
     fhir:index 7;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "TNMRegionalNodesVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"TNMRegionalNodesVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;TNMRegionalNodesVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMRegionalNodesVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: TNMRegionalNodesVS</p><p><b>title</b>: TNM Regional Nodes ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the TNM stage for the N category, according to TNM staging rules</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 1229966003</p><p><b>display</b>: American Joint Committee on Cancer cNX</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229967007</p><p><b>display</b>: American Joint Committee on Cancer cN0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229973008</p><p><b>display</b>: American Joint Committee on Cancer cN1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229978004</p><p><b>display</b>: American Joint Committee on Cancer cN2</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229984001</p><p><b>display</b>: American Joint Committee on Cancer cN3</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229945006</p><p><b>display</b>: American Joint Committee on Cancer pNX</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229947003</p><p><b>display</b>: American Joint Committee on Cancer pN0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229951001</p><p><b>display</b>: American Joint Committee on Cancer pN1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229957002</p><p><b>display</b>: American Joint Committee on Cancer pN2</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229962001</p><p><b>display</b>: American Joint Committee on Cancer pN3</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMRegionalNodesVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "TNMRegionalNodesVS" ];
       fhir:ValueSet.title [ fhir:value "TNM Regional Nodes ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the TNM stage for the N category, according to TNM staging rules" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229966003" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cNX" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229967007" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cN0" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229973008" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cN1" ]           ], [
             fhir:index 3;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229978004" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cN2" ]           ], [
             fhir:index 4;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229984001" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cN3" ]           ], [
             fhir:index 5;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229945006" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pNX" ]           ], [
             fhir:index 6;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229947003" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pN0" ]           ], [
             fhir:index 7;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229951001" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pN1" ]           ], [
             fhir:index 8;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229957002" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pN2" ]           ], [
             fhir:index 9;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229962001" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pN3" ]           ]         ], [
           fhir:index 1;
           fhir:ValueSet.compose.include.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-NullFlavor" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "UNK" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "unknown" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/TNMRegionalNodesVS" ]     ]
  ], [
     fhir:index 8;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "TNMDistantMetastasesVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"TNMDistantMetastasesVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;TNMDistantMetastasesVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMDistantMetastasesVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: TNMDistantMetastasesVS</p><p><b>title</b>: TNM Distant Metastases ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the TNM stage for the M category, according to TNM staging rules</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 1229901006</p><p><b>display</b>: American Joint Committee on Cancer cM0</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229903009</p><p><b>display</b>: American Joint Committee on Cancer cM1</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 1229916009</p><p><b>display</b>: American Joint Committee on Cancer pM1</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMDistantMetastasesVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "TNMDistantMetastasesVS" ];
       fhir:ValueSet.title [ fhir:value "TNM Distant Metastases ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the TNM stage for the M category, according to TNM staging rules" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229901006" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cM0" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229903009" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer cM1" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "1229916009" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "American Joint Committee on Cancer pM1" ]           ]         ], [
           fhir:index 1;
           fhir:ValueSet.compose.include.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-NullFlavor" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "UNK" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "unknown" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/TNMDistantMetastasesVS" ]     ]
  ], [
     fhir:index 9;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "EstrogenStatusVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"EstrogenStatusVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;EstrogenStatusVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/EstrogenStatusVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: EstrogenStatusVS</p><p><b>title</b>: Estrogen receptor status ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the Estrogen receptor status</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 373572006</p><p><b>display</b>: Clinical finding absent</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416053008</p><p><b>display</b>: Estrogen receptor positive tumor</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416237000</p><p><b>display</b>: Procedure not done</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/EstrogenStatusVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "EstrogenStatusVS" ];
       fhir:ValueSet.title [ fhir:value "Estrogen receptor status ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the Estrogen receptor status" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "373572006" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Clinical finding absent" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "416053008" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Estrogen receptor positive tumor" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "416237000" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Procedure not done" ]           ]         ], [
           fhir:index 1;
           fhir:ValueSet.compose.include.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-NullFlavor" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "UNK" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "unknown" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/EstrogenStatusVS" ]     ]
  ], [
     fhir:index 10;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "ProgesteroneStatusVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"ProgesteroneStatusVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;ProgesteroneStatusVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/ProgesteroneStatusVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: ProgesteroneStatusVS</p><p><b>title</b>: Progesterone receptor status ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the Progesterone receptor status</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 441118006</p><p><b>display</b>: Progesterone receptor negative neoplasm</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416561008</p><p><b>display</b>: Progesterone receptor positive tumor</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416237000</p><p><b>display</b>: Procedure not done</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-NullFlavor.html\">NullFlavor</a></p><h3>Concepts</h3><table class=\"grid\"><tr><td>-</td><td><b>Code</b></td><td><b>Display</b></td></tr><tr><td>*</td><td>UNK</td><td>unknown</td></tr></table></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/ProgesteroneStatusVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "ProgesteroneStatusVS" ];
       fhir:ValueSet.title [ fhir:value "Progesterone receptor status ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the Progesterone receptor status" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "441118006" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Progesterone receptor negative neoplasm" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "416561008" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Progesterone receptor positive tumor" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "416237000" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Procedure not done" ]           ]         ], [
           fhir:index 1;
           fhir:ValueSet.compose.include.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-NullFlavor" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "UNK" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "unknown" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/ProgesteroneStatusVS" ]     ]
  ], [
     fhir:index 11;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "HER2ReceptorStatusVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"HER2ReceptorStatusVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;HER2ReceptorStatusVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HER2ReceptorStatusVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: HER2ReceptorStatusVS</p><p><b>title</b>: HER2 receptor status ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the HER2 receptor status</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 431396003</p><p><b>display</b>: Human epidermal growth factor 2 negative carcinoma of breast</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 427685000</p><p><b>display</b>: Human epidermal growth factor 2 positive carcinoma of breast</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 280414007</p><p><b>display</b>: Equivocal result</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 416237000</p><p><b>display</b>: Procedure not done</p></blockquote></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HER2ReceptorStatusVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "HER2ReceptorStatusVS" ];
       fhir:ValueSet.title [ fhir:value "HER2 receptor status ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the HER2 receptor status" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "431396003" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Human epidermal growth factor 2 negative carcinoma of breast" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "427685000" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Human epidermal growth factor 2 positive carcinoma of breast" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "280414007" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Equivocal result" ]           ], [
             fhir:index 3;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "416237000" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Procedure not done" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/HER2ReceptorStatusVS" ]     ]
  ], [
     fhir:index 12;
     fhir:Bundle.entry.resource [
       a fhir:CodeSystem;
       fhir:Resource.id [ fhir:value "MolecularProfilingCodeSystem" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: CodeSystem</b><a name=\"MolecularProfilingCodeSystem\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource CodeSystem &quot;MolecularProfilingCodeSystem&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: MolecularProfilingCodeSystem</p><p><b>title</b>: Molecular Profiling CodeSystem</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Codes used to describe the different types of molecular profiling scoring</p><p><b>caseSensitive</b>: true</p><p><b>content</b>: complete</p><p><b>count</b>: 3</p><blockquote><p><b>concept</b></p><p><b>code</b>: mammaprint</p><p><b>display</b>: Mammaprint Score</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: oncotype</p><p><b>display</b>: Oncotype Score</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: endopredict</p><p><b>display</b>: Endopredict Score</p></blockquote></div>"       ];
       fhir:CodeSystem.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem" ];
       fhir:CodeSystem.version [ fhir:value "5.1" ];
       fhir:CodeSystem.name [ fhir:value "MolecularProfilingCodeSystem" ];
       fhir:CodeSystem.title [ fhir:value "Molecular Profiling CodeSystem" ];
       fhir:CodeSystem.status [ fhir:value "active" ];
       fhir:CodeSystem.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:CodeSystem.publisher [ fhir:value "ICHOM" ];
       fhir:CodeSystem.description [ fhir:value "Codes used to describe the different types of molecular profiling scoring" ];
       fhir:CodeSystem.caseSensitive [ fhir:value "true"^^xsd:boolean ];
       fhir:CodeSystem.content [ fhir:value "complete" ];
       fhir:CodeSystem.count [ fhir:value "3"^^xsd:nonNegativeInteger ];
       fhir:CodeSystem.concept [
         fhir:index 0;
         fhir:CodeSystem.concept.code [ fhir:value "mammaprint" ];
         fhir:CodeSystem.concept.display [ fhir:value "Mammaprint Score" ]       ], [
         fhir:index 1;
         fhir:CodeSystem.concept.code [ fhir:value "oncotype" ];
         fhir:CodeSystem.concept.display [ fhir:value "Oncotype Score" ]       ], [
         fhir:index 2;
         fhir:CodeSystem.concept.code [ fhir:value "endopredict" ];
         fhir:CodeSystem.concept.display [ fhir:value "Endopredict Score" ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "CodeSystem/MolecularProfilingCodeSystem" ]     ]
  ], [
     fhir:index 13;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "MolecularProfilingStatusVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"MolecularProfilingStatusVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;MolecularProfilingStatusVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/MolecularProfilingStatusVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: MolecularProfilingStatusVS</p><p><b>title</b>: Molecular profiling</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset indicating if a molecular profiling tool was used</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Molecular Profiling CodeSystem</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: mammaprint</p><p><b>display</b>: Mammaprint Score</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: oncotype</p><p><b>display</b>: Oncotype Score</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: endopredict</p><p><b>display</b>: Endopredict Score</p></blockquote></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/MolecularProfilingStatusVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "MolecularProfilingStatusVS" ];
       fhir:ValueSet.title [ fhir:value "Molecular profiling" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset indicating if a molecular profiling tool was used" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "mammaprint" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Mammaprint Score" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "oncotype" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Oncotype Score" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "endopredict" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Endopredict Score" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/MolecularProfilingStatusVS" ]     ]
  ], [
     fhir:index 14;
     fhir:Bundle.entry.resource [
       a fhir:ValueSet;
       fhir:Resource.id [ fhir:value "RecommendedTreatmentTypeVS" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "generated" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ValueSet</b><a name=\"RecommendedTreatmentTypeVS\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ValueSet &quot;RecommendedTreatmentTypeVS&quot; </p></div><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/RecommendedTreatmentTypeVS</code></p><p><b>version</b>: 5.1</p><p><b>name</b>: RecommendedTreatmentTypeVS</p><p><b>title</b>: Recommended treatment types ValueSet</p><p><b>status</b>: active</p><p><b>experimental</b>: false</p><p><b>publisher</b>: ICHOM</p><p><b>description</b>: Valueset of the kind of treatment that the multidisciplinary team recommended</p><p><b>copyright</b>: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement</p><blockquote><p><b>compose</b></p><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"http://hl7.org/fhir/R4/codesystem-snomedct.html\">SNOMED CT (all versions)</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: 387713003</p><p><b>display</b>: Surgical procedure</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 108290001</p><p><b>display</b>: Radiation oncology AND/OR radiotherapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 169413002</p><p><b>display</b>: Hormone therapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 76334006</p><p><b>display</b>: Immunotherapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: 243114000</p><p><b>display</b>: Support</p></blockquote></blockquote><blockquote><p><b>include</b></p><p><b>system</b>: <a href=\"Bundle-DebugBundleClinical-03-Annual.html\">Treatment variables CodeSytem</a></p><blockquote><p><b>concept</b></p><p><b>code</b>: adjuvant-chemotherapy</p><p><b>display</b>: Adjuvant chemotherapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: neoadjuvant-chemotherapy</p><p><b>display</b>: Neoadjuvant chemotherapy</p></blockquote><blockquote><p><b>concept</b></p><p><b>code</b>: targeted-therapy</p><p><b>display</b>: Targeted therapy</p></blockquote></blockquote></blockquote></div>"       ];
       fhir:ValueSet.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/RecommendedTreatmentTypeVS" ];
       fhir:ValueSet.version [ fhir:value "5.1" ];
       fhir:ValueSet.name [ fhir:value "RecommendedTreatmentTypeVS" ];
       fhir:ValueSet.title [ fhir:value "Recommended treatment types ValueSet" ];
       fhir:ValueSet.status [ fhir:value "active" ];
       fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean ];
       fhir:ValueSet.publisher [ fhir:value "ICHOM" ];
       fhir:ValueSet.description [ fhir:value "Valueset of the kind of treatment that the multidisciplinary team recommended" ];
       fhir:ValueSet.copyright [ fhir:value "This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement" ];
       fhir:ValueSet.compose [
         fhir:ValueSet.compose.include [
           fhir:index 0;
           fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "387713003" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Surgical procedure" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "108290001" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Radiation oncology AND/OR radiotherapy" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "169413002" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Hormone therapy" ]           ], [
             fhir:index 3;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "76334006" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Immunotherapy" ]           ], [
             fhir:index 4;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "243114000" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Support" ]           ]         ], [
           fhir:index 1;
           fhir:ValueSet.compose.include.system [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/TreatmentTypesCodeSystem" ];
           fhir:ValueSet.compose.include.concept [
             fhir:index 0;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "adjuvant-chemotherapy" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Adjuvant chemotherapy" ]           ], [
             fhir:index 1;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "neoadjuvant-chemotherapy" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Neoadjuvant chemotherapy" ]           ], [
             fhir:index 2;
             fhir:ValueSet.compose.include.concept.code [ fhir:value "targeted-therapy" ];
             fhir:ValueSet.compose.include.concept.display [ fhir:value "Targeted therapy" ]           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "ValueSet/RecommendedTreatmentTypeVS" ]     ]
  ], [
     fhir:index 15;
     fhir:Bundle.entry.resource [
       a fhir:Questionnaire;
       fhir:Resource.id [ fhir:value "ClinicalResponseBaseline" ];
       fhir:DomainResource.text [
         fhir:Narrative.status [ fhir:value "extensions" ];
         fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Questionnaire</b><a name=\"ClinicalResponseBaseline\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Questionnaire &quot;ClinicalResponseBaseline&quot; </p></div><blockquote><p><b>Launch context resources</b></p><p><b>value</b>: Patient (Details: http://hl7.org/fhir/uv/sdc/CodeSystem/launchContext code patient = 'Patient', stated as 'Patient')</p><p><b>value</b>: Patient</p><p><b>value</b>: Patient information to pre-populate the form with</p></blockquote><p><b>url</b>: <code>http://hl7.org/fhir/uv/ichom-breast-cancer/Questionnaire/ClinicalResponseBaseline</code></p><p><b>name</b>: ClinicalResponseBaseline</p><p><b>title</b>: Clinical response questionnaire at baseline</p><p><b>status</b>: draft</p><p><b>experimental</b>: true</p><p><b>publisher</b>: ICHOM</p><blockquote><p><b>item</b></p><p><b>linkId</b>: General-Information-Clinical</p><p><b>text</b>: General information</p><p><b>type</b>: group</p><p><b>required</b>: true</p><h3>Items</h3><table class=\"grid\"><tr><td>-</td><td><b>Extension</b></td><td><b>LinkId</b></td><td><b>Text</b></td><td><b>Type</b></td><td><b>Required</b></td></tr><tr><td>*</td><td/><td>NA-Clinical</td><td>What is the patient's medical record number?</td><td>string</td><td>true</td></tr><tr><td>*</td><td/><td>LastName-Clinical</td><td>What is the patient's last name?</td><td>string</td><td>true</td></tr></table></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Demographics</p><p><b>text</b>: Demographic factors</p><p><b>type</b>: group</p><p><b>required</b>: true</p><h3>Items</h3><table class=\"grid\"><tr><td>-</td><td><b>Extension</b></td><td><b>LinkId</b></td><td><b>Text</b></td><td><b>Type</b></td><td><b>Required</b></td><td><b>MaxLength</b></td><td><b>AnswerValueSet</b></td></tr><tr><td>*</td><td>, </td><td>Sex</td><td>Indicate the sex of the patient at birth:</td><td>choice</td><td>true</td><td> </td><td><a href=\"http://hl7.org/fhir/R4/valueset-administrative-gender.html\">AdministrativeGender</a></td></tr><tr><td>*</td><td/><td>YearOfBirth</td><td>In what year was the patient born?</td><td>integer</td><td>true</td><td>4</td><td> </td></tr></table></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Clinical-Factors</p><p><b>text</b>: Clinical factors</p><p><b>type</b>: group</p><p><b>required</b>: true</p><blockquote><p><b>item</b></p><p><b>Obervation link period</b>: 300 a<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code a = 'a')</span></p><p><b>Observation extract</b>: true</p><p><b>unitOption</b>: cm (Details: UCUM code cm = 'cm', stated as 'cm')</p><p><b>Min quantity</b>: 10 cm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code cm = 'cm')</span></p><p><b>Max quantity</b>: 320 cm<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code cm = 'cm')</span></p><p><b>unitOption</b>: [in_i] (Details: UCUM code [in_i] = '[in_i]', stated as '[in_i]')</p><p><b>Min quantity</b>: 3.94 [in_i]<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [in_i] = '[in_i]')</span></p><p><b>Max quantity</b>: 126 [in_i]<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [in_i] = '[in_i]')</span></p><p><b>linkId</b>: Height</p><p><b>code</b>: Body height (Details: LOINC code 8302-2 = 'Body height', stated as 'Body height')</p><p><b>text</b>: Indicate the patient's body height</p><p><b>type</b>: quantity</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>Obervation link period</b>: 300 a<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code a = 'a')</span></p><p><b>Observation extract</b>: true</p><p><b>unitOption</b>: kg (Details: UCUM code kg = 'kg', stated as 'kg')</p><p><b>Min quantity</b>: 0.1 kg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code kg = 'kg')</span></p><p><b>Max quantity</b>: 750 kg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code kg = 'kg')</span></p><p><b>unitOption</b>: [lb_av] (Details: UCUM code [lb_av] = '[lb_av]', stated as '[lb_av]')</p><p><b>Min quantity</b>: 0.22 [lb_av]<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [lb_av] = '[lb_av]')</span></p><p><b>Max quantity</b>: 1653.47 [lb_av]<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code [lb_av] = '[lb_av]')</span></p><p><b>linkId</b>: Weight</p><p><b>code</b>: Body weight (Details: LOINC code 29463-7 = 'Body weight', stated as 'Body weight'), Body weight Measured (Details: LOINC code 3141-9 = 'Body weight Measured', stated as 'Body weight Measured'), Body weight (Details: SNOMED CT code 27113001 = 'Body weight', stated as 'Body weight')</p><p><b>text</b>: Indicate the patient's weight.</p><p><b>type</b>: quantity</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: LATERAL</p><p><b>text</b>: Indicate the laterality of breast cancer</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Laterality of breast cancer ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: FIRSTBC</p><p><b>text</b>: Indicate if this is the first breast cancer</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-03-Annual.html\">Yes, No and Unknown Valueset</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: NewBC</p><p><b>text</b>: Indicate if this is a new cancer on contralateral or ipsilateral breast</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Laterality of new cancer ValueSet</a></p></blockquote></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Tumor-Factors</p><p><b>text</b>: Tumor factors</p><p><b>type</b>: group</p><p><b>required</b>: true</p><blockquote><p><b>item</b></p><p><b>linkId</b>: HistologicalDateKnown</p><p><b>text</b>: Is the date of histological diagnosis known?</p><p><b>type</b>: boolean</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: HistologicalDiagnosisDate</p><p><b>text</b>: Indicate the initial date of histological diagnosis:</p><p><b>type</b>: date</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: HISTOTYPE</p><p><b>text</b>: Indicate the histologic type of the tumor (select all that apply)</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>repeats</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Histological type of the tumor ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: MUTBC</p><p><b>text</b>: Indicate if the patient carries a germline mutation predisposing breast cancer</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>repeats</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-03-Annual.html\">Germline Mutation ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: GRADEINV</p><p><b>text</b>: Indicate the grade of the invasive component of tumor</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Grading of tumor ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: GRADEDCIS</p><p><b>text</b>: Indicate the tumor grade of DCIS component of tumor</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Grading of tumor ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: TNMCT_BREAST</p><p><b>text</b>: Indicate the clinical tumor stage (per AJCC 8th Ed.):</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-02-SixMonths.html\">TNM Primary Tumor ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: TNMCN_BREAST</p><p><b>text</b>: Indicate the clinical nodal stage (per AJCC 8th Ed.):</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-02-SixMonths.html\">TNM Regional Nodes ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: TNMCM_BREAST</p><p><b>text</b>: Indicate the clinical distant metastasis (per AJCC 8th Ed.):</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-02-SixMonths.html\">TNM Distant Metastases ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: ERSTATUS</p><p><b>text</b>: Indicate if the estrogen receptor status is positive:</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Estrogen receptor status ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: PRSTATUS</p><p><b>text</b>: Indicate if the progesterone receptor status is positive:</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Progesterone receptor status ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: HER2STATUS</p><p><b>text</b>: Indicate if the HER2 receptor status is positive:</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">HER2 receptor status ValueSet</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: MolecularProfiling</p><p><b>text</b>: Indicate if a molecular profiling tool was used. If so, which one?</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Molecular profiling</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Mammaprint</p><p><b>text</b>: Indicate the mammaprint score on a scale of 0.000 to 1.000</p><p><b>type</b>: decimal</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Oncotype</p><p><b>text</b>: Indicate the oncotype score on a scale of 0 to 100</p><p><b>type</b>: decimal</p><p><b>required</b>: true</p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Endopredict</p><p><b>text</b>: Indicate the endopredict score on a scale of 1.1 to 6.2</p><p><b>type</b>: decimal</p><p><b>required</b>: true</p></blockquote></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: Treatment-Variables</p><p><b>text</b>: Treatment variables</p><p><b>type</b>: group</p><p><b>required</b>: true</p><blockquote><p><b>item</b></p><p><b>linkId</b>: MultMeet</p><p><b>text</b>: Indicate if a multidisciplinary meeting was conducted</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-03-Annual.html\">Yes, No and Unknown Valueset</a></p></blockquote><blockquote><p><b>item</b></p><p><b>linkId</b>: MultRecTreatments</p><p><b>text</b>: Which treatments did the multidisciplinary team recommend (select all that apply)?</p><p><b>type</b>: choice</p><p><b>required</b>: true</p><p><b>repeats</b>: true</p><p><b>answerValueSet</b>: <a href=\"Bundle-DebugBundleClinical-01-Baseline.html\">Recommended treatment types ValueSet</a></p></blockquote></blockquote></div>"       ];
       fhir:DomainResource.extension [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "name" ];
           fhir:Extension.valueCoding [
             fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/sdc/CodeSystem/launchContext" ];
             fhir:Coding.code [ fhir:value "patient" ];
             fhir:Coding.display [ fhir:value "Patient" ]           ]         ], [
           fhir:index 1;
           fhir:Extension.url [ fhir:value "type" ];
           fhir:Extension.valueCode [ fhir:value "Patient" ]         ], [
           fhir:index 2;
           fhir:Extension.url [ fhir:value "description" ];
           fhir:Extension.valueString [ fhir:value "Patient information to pre-populate the form with" ]         ];
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-launchContext" ]       ];
       fhir:Questionnaire.url [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/Questionnaire/ClinicalResponseBaseline" ];
       fhir:Questionnaire.name [ fhir:value "ClinicalResponseBaseline" ];
       fhir:Questionnaire.title [ fhir:value "Clinical response questionnaire at baseline" ];
       fhir:Questionnaire.status [ fhir:value "draft" ];
       fhir:Questionnaire.experimental [ fhir:value "true"^^xsd:boolean ];
       fhir:Questionnaire.publisher [ fhir:value "ICHOM" ];
       fhir:Questionnaire.item [
         fhir:index 0;
         fhir:Questionnaire.item.linkId [ fhir:value "General-Information-Clinical" ];
         fhir:Questionnaire.item.text [ fhir:value "General information" ];
         fhir:Questionnaire.item.type [ fhir:value "group" ];
         fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
         fhir:Questionnaire.item.item [
           fhir:index 0;
           fhir:Element.extension [
             fhir:index 0;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-initialExpression" ];
             fhir:Extension.valueExpression [
               fhir:Expression.language [ fhir:value "text/fhirpath" ];
               fhir:Expression.expression [ fhir:value "%patient.id" ]             ]           ];
           fhir:Questionnaire.item.linkId [ fhir:value "NA-Clinical" ];
           fhir:Questionnaire.item.text [ fhir:value "What is the patient's medical record number?" ];
           fhir:Questionnaire.item.type [ fhir:value "string" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ]         ], [
           fhir:index 1;
           fhir:Element.extension [
             fhir:index 0;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-initialExpression" ];
             fhir:Extension.valueExpression [
               fhir:Expression.language [ fhir:value "text/fhirpath" ];
               fhir:Expression.expression [ fhir:value "%patient.name.first().family.first()" ]             ]           ];
           fhir:Questionnaire.item.linkId [ fhir:value "LastName-Clinical" ];
           fhir:Questionnaire.item.text [ fhir:value "What is the patient's last name?" ];
           fhir:Questionnaire.item.type [ fhir:value "string" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ]         ]       ], [
         fhir:index 1;
         fhir:Questionnaire.item.linkId [ fhir:value "Demographics" ];
         fhir:Questionnaire.item.text [ fhir:value "Demographic factors" ];
         fhir:Questionnaire.item.type [ fhir:value "group" ];
         fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
         fhir:Questionnaire.item.item [
           fhir:index 0;
           fhir:Element.extension [
             fhir:index 0;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/variable" ];
             fhir:Extension.valueExpression [
               fhir:Expression.name [ fhir:value "expandedGender" ];
               fhir:Expression.language [ fhir:value "application/x-fhir-query" ];
               fhir:Expression.expression [ fhir:value "ValueSet/$expand?url=http://hl7.org/fhir/ValueSet/administrative-gender" ]             ]           ], [
             fhir:index 1;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-initialExpression" ];
             fhir:Extension.valueExpression [
               fhir:Expression.language [ fhir:value "text/fhirpath" ];
               fhir:Expression.expression [ fhir:value "%expandedGender.expansion.contains.where(code=%patient.gender)" ]             ]           ];
           fhir:Questionnaire.item.linkId [ fhir:value "Sex" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the sex of the patient at birth:" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/ValueSet/administrative-gender";
             fhir:link <http://hl7.org/fhir/ValueSet/administrative-gender>           ]         ], [
           fhir:index 1;
           fhir:Element.extension [
             fhir:index 0;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-initialExpression" ];
             fhir:Extension.valueExpression [
               fhir:Expression.language [ fhir:value "text/fhirpath" ];
               fhir:Expression.expression [ fhir:value "%patient.birthDate.substring(0,4)" ]             ]           ];
           fhir:Questionnaire.item.linkId [ fhir:value "YearOfBirth" ];
           fhir:Questionnaire.item.text [ fhir:value "In what year was the patient born?" ];
           fhir:Questionnaire.item.type [ fhir:value "integer" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.maxLength [ fhir:value "4"^^xsd:integer ]         ]       ], [
         fhir:index 2;
         fhir:Questionnaire.item.linkId [ fhir:value "Clinical-Factors" ];
         fhir:Questionnaire.item.text [ fhir:value "Clinical factors" ];
         fhir:Questionnaire.item.type [ fhir:value "group" ];
         fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
         fhir:Questionnaire.item.item [
           fhir:index 0;
           fhir:Element.extension [
             fhir:index 0;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-observationLinkPeriod" ];
             fhir:Extension.valueDuration [
               fhir:Quantity.value [ fhir:value "300"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "a" ]             ]           ], [
             fhir:index 1;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-observationExtract" ];
             fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]           ], [
             fhir:index 2;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption" ];
             fhir:Extension.valueCoding [
               fhir:Coding.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Coding.code [ fhir:value "cm" ];
               fhir:Coding.display [ fhir:value "cm" ]             ]           ], [
             fhir:index 3;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-minQuantity" ];
             fhir:Extension.valueQuantity [
               fhir:Quantity.value [ fhir:value "10"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "cm" ]             ]           ], [
             fhir:index 4;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-maxQuantity" ];
             fhir:Extension.valueQuantity [
               fhir:Quantity.value [ fhir:value "320"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "cm" ]             ]           ], [
             fhir:index 5;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption" ];
             fhir:Extension.valueCoding [
               fhir:Coding.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Coding.code [ fhir:value "[in_i]" ];
               fhir:Coding.display [ fhir:value "[in_i]" ]             ]           ], [
             fhir:index 6;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-minQuantity" ];
             fhir:Extension.valueQuantity [
               fhir:Quantity.value [ fhir:value "3.94"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "[in_i]" ]             ]           ], [
             fhir:index 7;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-maxQuantity" ];
             fhir:Extension.valueQuantity [
               fhir:Quantity.value [ fhir:value "126"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "[in_i]" ]             ]           ];
           fhir:Questionnaire.item.linkId [ fhir:value "Height" ];
           fhir:Questionnaire.item.code [
             fhir:index 0;
             a loinc:8302-2;
             fhir:Coding.system [ fhir:value "http://loinc.org" ];
             fhir:Coding.code [ fhir:value "8302-2" ];
             fhir:Coding.display [ fhir:value "Body height" ]           ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the patient's body height" ];
           fhir:Questionnaire.item.type [ fhir:value "quantity" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ]         ], [
           fhir:index 1;
           fhir:Element.extension [
             fhir:index 0;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-observationLinkPeriod" ];
             fhir:Extension.valueDuration [
               fhir:Quantity.value [ fhir:value "300"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "a" ]             ]           ], [
             fhir:index 1;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-observationExtract" ];
             fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]           ], [
             fhir:index 2;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption" ];
             fhir:Extension.valueCoding [
               fhir:Coding.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Coding.code [ fhir:value "kg" ];
               fhir:Coding.display [ fhir:value "kg" ]             ]           ], [
             fhir:index 3;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-minQuantity" ];
             fhir:Extension.valueQuantity [
               fhir:Quantity.value [ fhir:value "0.1"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "kg" ]             ]           ], [
             fhir:index 4;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-maxQuantity" ];
             fhir:Extension.valueQuantity [
               fhir:Quantity.value [ fhir:value "750"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "kg" ]             ]           ], [
             fhir:index 5;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/questionnaire-unitOption" ];
             fhir:Extension.valueCoding [
               fhir:Coding.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Coding.code [ fhir:value "[lb_av]" ];
               fhir:Coding.display [ fhir:value "[lb_av]" ]             ]           ], [
             fhir:index 6;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-minQuantity" ];
             fhir:Extension.valueQuantity [
               fhir:Quantity.value [ fhir:value "0.22"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "[lb_av]" ]             ]           ], [
             fhir:index 7;
             fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/sdc/StructureDefinition/sdc-questionnaire-maxQuantity" ];
             fhir:Extension.valueQuantity [
               fhir:Quantity.value [ fhir:value "1653.47"^^xsd:decimal ];
               fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
               fhir:Quantity.code [ fhir:value "[lb_av]" ]             ]           ];
           fhir:Questionnaire.item.linkId [ fhir:value "Weight" ];
           fhir:Questionnaire.item.code [
             fhir:index 0;
             a loinc:29463-7;
             fhir:Coding.system [ fhir:value "http://loinc.org" ];
             fhir:Coding.code [ fhir:value "29463-7" ];
             fhir:Coding.display [ fhir:value "Body weight" ]           ], [
             fhir:index 1;
             a loinc:3141-9;
             fhir:Coding.system [ fhir:value "http://loinc.org" ];
             fhir:Coding.code [ fhir:value "3141-9" ];
             fhir:Coding.display [ fhir:value "Body weight Measured" ]           ], [
             fhir:index 2;
             a sct:27113001;
             fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
             fhir:Coding.code [ fhir:value "27113001" ];
             fhir:Coding.display [ fhir:value "Body weight" ]           ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the patient's weight." ];
           fhir:Questionnaire.item.type [ fhir:value "quantity" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ]         ], [
           fhir:index 2;
           fhir:Questionnaire.item.linkId [ fhir:value "LATERAL" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the laterality of breast cancer" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityVS>           ]         ], [
           fhir:index 3;
           fhir:Questionnaire.item.linkId [ fhir:value "FIRSTBC" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate if this is the first breast cancer" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS>           ]         ], [
           fhir:index 4;
           fhir:Questionnaire.item.linkId [ fhir:value "NewBC" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate if this is a new cancer on contralateral or ipsilateral breast" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.enableWhen [
             fhir:index 0;
             fhir:Questionnaire.item.enableWhen.question [ fhir:value "FIRSTBC" ];
             fhir:Questionnaire.item.enableWhen.operator [ fhir:value "=" ];
             fhir:Questionnaire.item.enableWhen.answerCoding [
               fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v2-0532" ];
               fhir:Coding.code [ fhir:value "N" ]             ]           ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityNewCancerVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/LateralityNewCancerVS>           ]         ]       ], [
         fhir:index 3;
         fhir:Questionnaire.item.linkId [ fhir:value "Tumor-Factors" ];
         fhir:Questionnaire.item.text [ fhir:value "Tumor factors" ];
         fhir:Questionnaire.item.type [ fhir:value "group" ];
         fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
         fhir:Questionnaire.item.item [
           fhir:index 0;
           fhir:Questionnaire.item.linkId [ fhir:value "HistologicalDateKnown" ];
           fhir:Questionnaire.item.text [ fhir:value "Is the date of histological diagnosis known?" ];
           fhir:Questionnaire.item.type [ fhir:value "boolean" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ]         ], [
           fhir:index 1;
           fhir:Questionnaire.item.linkId [ fhir:value "HistologicalDiagnosisDate" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the initial date of histological diagnosis:" ];
           fhir:Questionnaire.item.type [ fhir:value "date" ];
           fhir:Questionnaire.item.enableWhen [
             fhir:index 0;
             fhir:Questionnaire.item.enableWhen.question [ fhir:value "HistologicalDateKnown" ];
             fhir:Questionnaire.item.enableWhen.operator [ fhir:value "=" ];
             fhir:Questionnaire.item.enableWhen.answerBoolean [ fhir:value "true"^^xsd:boolean ]           ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ]         ], [
           fhir:index 2;
           fhir:Questionnaire.item.linkId [ fhir:value "HISTOTYPE" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the histologic type of the tumor (select all that apply)" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.repeats [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HistologicalTypeVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HistologicalTypeVS>           ]         ], [
           fhir:index 3;
           fhir:Questionnaire.item.linkId [ fhir:value "MUTBC" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate if the patient carries a germline mutation predisposing breast cancer" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.repeats [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GermlineMutationVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GermlineMutationVS>           ]         ], [
           fhir:index 4;
           fhir:Questionnaire.item.linkId [ fhir:value "GRADEINV" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the grade of the invasive component of tumor" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS>           ]         ], [
           fhir:index 5;
           fhir:Questionnaire.item.linkId [ fhir:value "GRADEDCIS" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the tumor grade of DCIS component of tumor" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/GradingVS>           ]         ], [
           fhir:index 6;
           fhir:Questionnaire.item.linkId [ fhir:value "TNMCT_BREAST" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the clinical tumor stage (per AJCC 8th Ed.):" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMPrimaryTumorVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMPrimaryTumorVS>           ]         ], [
           fhir:index 7;
           fhir:Questionnaire.item.linkId [ fhir:value "TNMCN_BREAST" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the clinical nodal stage (per AJCC 8th Ed.):" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMRegionalNodesVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMRegionalNodesVS>           ]         ], [
           fhir:index 8;
           fhir:Questionnaire.item.linkId [ fhir:value "TNMCM_BREAST" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the clinical distant metastasis (per AJCC 8th Ed.):" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMDistantMetastasesVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/TNMDistantMetastasesVS>           ]         ], [
           fhir:index 9;
           fhir:Questionnaire.item.linkId [ fhir:value "ERSTATUS" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate if the estrogen receptor status is positive:" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/EstrogenStatusVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/EstrogenStatusVS>           ]         ], [
           fhir:index 10;
           fhir:Questionnaire.item.linkId [ fhir:value "PRSTATUS" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate if the progesterone receptor status is positive:" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/ProgesteroneStatusVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/ProgesteroneStatusVS>           ]         ], [
           fhir:index 11;
           fhir:Questionnaire.item.linkId [ fhir:value "HER2STATUS" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate if the HER2 receptor status is positive:" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HER2ReceptorStatusVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/HER2ReceptorStatusVS>           ]         ], [
           fhir:index 12;
           fhir:Questionnaire.item.linkId [ fhir:value "MolecularProfiling" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate if a molecular profiling tool was used. If so, which one?" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/MolecularProfilingStatusVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/MolecularProfilingStatusVS>           ]         ], [
           fhir:index 13;
           fhir:Questionnaire.item.linkId [ fhir:value "Mammaprint" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the mammaprint score on a scale of 0.000 to 1.000" ];
           fhir:Questionnaire.item.type [ fhir:value "decimal" ];
           fhir:Questionnaire.item.enableWhen [
             fhir:index 0;
             fhir:Questionnaire.item.enableWhen.question [ fhir:value "MolecularProfiling" ];
             fhir:Questionnaire.item.enableWhen.operator [ fhir:value "=" ];
             fhir:Questionnaire.item.enableWhen.answerCoding [
               fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem" ];
               fhir:Coding.code [ fhir:value "mammaprint" ]             ]           ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ]         ], [
           fhir:index 14;
           fhir:Questionnaire.item.linkId [ fhir:value "Oncotype" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the oncotype score on a scale of 0 to 100" ];
           fhir:Questionnaire.item.type [ fhir:value "decimal" ];
           fhir:Questionnaire.item.enableWhen [
             fhir:index 0;
             fhir:Questionnaire.item.enableWhen.question [ fhir:value "MolecularProfiling" ];
             fhir:Questionnaire.item.enableWhen.operator [ fhir:value "=" ];
             fhir:Questionnaire.item.enableWhen.answerCoding [
               fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem" ];
               fhir:Coding.code [ fhir:value "oncotype" ]             ]           ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ]         ], [
           fhir:index 15;
           fhir:Questionnaire.item.linkId [ fhir:value "Endopredict" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate the endopredict score on a scale of 1.1 to 6.2" ];
           fhir:Questionnaire.item.type [ fhir:value "decimal" ];
           fhir:Questionnaire.item.enableWhen [
             fhir:index 0;
             fhir:Questionnaire.item.enableWhen.question [ fhir:value "MolecularProfiling" ];
             fhir:Questionnaire.item.enableWhen.operator [ fhir:value "=" ];
             fhir:Questionnaire.item.enableWhen.answerCoding [
               fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/CodeSystem/MolecularProfilingCodeSystem" ];
               fhir:Coding.code [ fhir:value "endopredict" ]             ]           ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ]         ]       ], [
         fhir:index 4;
         fhir:Questionnaire.item.linkId [ fhir:value "Treatment-Variables" ];
         fhir:Questionnaire.item.text [ fhir:value "Treatment variables" ];
         fhir:Questionnaire.item.type [ fhir:value "group" ];
         fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
         fhir:Questionnaire.item.item [
           fhir:index 0;
           fhir:Questionnaire.item.linkId [ fhir:value "MultMeet" ];
           fhir:Questionnaire.item.text [ fhir:value "Indicate if a multidisciplinary meeting was conducted" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/NoYesUnknownVS>           ]         ], [
           fhir:index 1;
           fhir:Questionnaire.item.linkId [ fhir:value "MultRecTreatments" ];
           fhir:Questionnaire.item.text [ fhir:value "Which treatments did the multidisciplinary team recommend (select all that apply)?" ];
           fhir:Questionnaire.item.type [ fhir:value "choice" ];
           fhir:Questionnaire.item.enableWhen [
             fhir:index 0;
             fhir:Questionnaire.item.enableWhen.question [ fhir:value "MultMeet" ];
             fhir:Questionnaire.item.enableWhen.operator [ fhir:value "=" ];
             fhir:Questionnaire.item.enableWhen.answerCoding [
               fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v2-0532" ];
               fhir:Coding.code [ fhir:value "Y" ]             ]           ];
           fhir:Questionnaire.item.required [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.repeats [ fhir:value "true"^^xsd:boolean ];
           fhir:Questionnaire.item.answerValueSet [
             fhir:value "http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/RecommendedTreatmentTypeVS";
             fhir:link <http://hl7.org/fhir/uv/ichom-breast-cancer/ValueSet/RecommendedTreatmentTypeVS>           ]         ]       ]     ];
     fhir:Bundle.entry.request [
       fhir:Bundle.entry.request.method [ fhir:value "PUT" ];
       fhir:Bundle.entry.request.url [ fhir:value "Questionnaire/ClinicalResponseBaseline" ]     ]
  ]. # 

# - ontology header ------------------------------------------------------------

 a owl:Ontology;
  owl:imports fhir:fhir.ttl.