Evidence Based Medicine on FHIR Implementation Guide
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This page is part of the Evidence Based Medicine on FHIR Implementation Guide (v1.0.0-ballot2: STU1 Ballot 2) based on FHIR (HL7® FHIR® Standard) v6.0.0. No current official version has been published yet. For a full list of available versions, see the Directory of published versions

: NetEffectContribution: Remission of diabetes for Example for GIN 2022 - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Evidence ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "179588"] ; # 
  fhir:meta [
fhir:versionId [ fhir:v "12" ] ;
fhir:lastUpdated [ fhir:v "2025-03-16T09:43:10.014Z"^^xsd:dateTime ] ;
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "empty" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"^^rdf:XMLLiteral
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/cite-as"^^xsd:anyURI ] ;
fhir:value [
a fhir:markdown ;
fhir:v "NetEffectContribution: Remission of diabetes for Example for GIN 2022 [Database Entry: FHIR Evidence Resource]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179588. Revised 2025-03-05. Available at: https://fevir.net/resources/Evidence/179588. Computable resource at: https://fevir.net/resources/Evidence/179588#json."     ]
  ] ) ; # 
  fhir:url [ fhir:v "https://fevir.net/resources/Evidence/179588"^^xsd:anyURI] ; # 
  fhir:identifier ( [
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ACSN" ] ;
fhir:display [ fhir:v "Accession ID" ]       ] ) ;
fhir:text [ fhir:v "FEvIR Object Identifier" ]     ] ;
fhir:system [ fhir:v "urn:ietf:rfc:3986"^^xsd:anyURI ] ;
fhir:value [ fhir:v "https://fevir.net/FOI/179588" ] ;
fhir:assigner [
fhir:display [ fhir:v "Computable Publishing LLC" ]     ]
  ] ) ; # 
  fhir:name [ fhir:v "NetEffectContribution_Remission_of_diabetes_for_Example_for_GIN_2022"] ; # 
  fhir:title [ fhir:v "NetEffectContribution: Remission of diabetes for Example for GIN 2022"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:publisher [ fhir:v "Computable Publishing LLC"] ; # 
  fhir:contact ( [
    ( fhir:telecom [
fhir:system [ fhir:v "email" ] ;
fhir:value [ fhir:v "support@computablepublishing.com" ]     ] )
  ] ) ; # 
  fhir:author ( [
fhir:name [ fhir:v "Brian S. Alper" ]
  ] ) ; # 
  fhir:useContext ( [
fhir:code [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "evidence-communication" ] ;
fhir:display [ fhir:v "Evidence Communication" ]     ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ComparativeEvidence" ] ;
fhir:display [ fhir:v "ComparativeEvidence" ]       ] )     ]
  ] [
fhir:code [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "evidence-communication" ] ;
fhir:display [ fhir:v "Evidence Communication" ]     ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "NetEffectContribution" ] ;
fhir:display [ fhir:v "NetEffectContribution" ]       ] )     ]
  ] ) ; # 
  fhir:copyright [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/"] ; # 
  fhir:description [ fhir:v "2.15 (1.33 to 3.26) - example showing statistic.extension:modelExpression"] ; # 
  fhir:variableDefinition ( [
fhir:description [ fhir:v "Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n = 2109) with severe obesity assessed (221 patients excluded and 1888 patients included)." ] ;
fhir:variableRole [ fhir:v "population" ] ;
fhir:observed [
fhir:reference [ fhir:v "Group/178427" ] ;
fhir:type [ fhir:v "Group"^^xsd:anyURI ] ;
fhir:display [ fhir:v "StudyGroup: Severely Obese Adults 2018 Norwegian Cohort" ]     ]
  ] [
fhir:description [ fhir:v "comparison groups of bariatric surgery vs. no bariatric surgery" ] ;
fhir:variableRole [ fhir:v "exposure" ] ;
fhir:comparatorCategory [ fhir:v "no bariatric surgery" ] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/172427" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "GroupAssignment: Bariatric Surgery vs. no bariatric surgery" ]     ]
  ] [
fhir:description [ fhir:v "Remission of diabetes" ] ;
fhir:variableRole [ fhir:v "outcome" ] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/104117" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: Remission of diabetes" ]     ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/relative-outcome-importance"^^xsd:anyURI ] ;
fhir:value [
a fhir:Reference ;
fhir:reference [ fhir:v "ArtifactAssessment/104193" ] ;
fhir:type [ fhir:v "ArtifactAssessment"^^xsd:anyURI ] ;
fhir:display [ fhir:v "Outcome Importance Rating 5% of Remission of diabetes" ]       ]     ] ) ;
fhir:description [ fhir:v "Relative Importance Multiplier" ] ;
fhir:variableRole [ fhir:v "covariate" ] ;
fhir:roleSubtype [
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "importance-multiplier" ] ;
fhir:display [ fhir:v "Relative importance multiplier" ]       ] )     ] ;
fhir:observed [
fhir:display [ fhir:v "Relative Importance Multiplier" ]     ]
  ] ) ; # 
  fhir:statistic ( [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/statistic-model-expression"^^xsd:anyURI ] ;
fhir:value [
a fhir:Expression ;
fhir:description [ fhir:v "risk difference (relative risk x control event rate) multiplied by relative importance multiplier (defined in OutcomeImportance Profile) -- expression is pseudocode to demonstrate the concept" ] ;
fhir:name [ fhir:v "Net effect contribution analysis" ] ;
fhir:expression [ fhir:v "Evidence[id='104121'].statistic[statisticType='Relative Risk'] * Evidence[id='104396'].statistic[statisticType='Proportion'] * ArtifactAssessment[id='104193'].content[type.text='Outcome Importance'].quantity" ]       ]     ] ) ;
fhir:description [ fhir:v "risk difference 2.15 (95% CI 1.33 to 3.26)" ] ;
fhir:statisticType [
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/sevco"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000424" ] ;
fhir:display [ fhir:v "risk difference" ]       ] )     ] ;
fhir:quantity [
fhir:value [ fhir:v 2.15 ]     ] ;
    ( fhir:attributeEstimate [
fhir:description [ fhir:v "95% CI 1.33 to 3.26" ] ;
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/sevco"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000196" ] ;
fhir:display [ fhir:v "confidence interval" ]         ] )       ] ;
fhir:level [ fhir:v 0.95 ] ;
fhir:range [
fhir:low [
fhir:value [ fhir:v 1.33 ]         ] ;
fhir:high [
fhir:value [ fhir:v 3.26 ]         ]       ]     ] ) ;
    ( fhir:modelCharacteristic [
fhir:code [
fhir:text [ fhir:v "Net effect contribution analysis" ]       ]     ] )
  ] ) . #