Generated Narrative: Evidence

StructureDefinition Work Group: cds

url: https://fevir.net/resources/Evidence/47758

identifier: FEvIR Object Identifier: 47758

version: 1.0.0-ballot

name: ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Schauer_2012_STAMPEDE_trial

title: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Schauer 2012 (STAMPEDE) trial

status: active

date: 2022-05-29 11:09:57+0000

publisher: HL7 International / Clinical Decision Support

contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss

author: Brian S. Alper:

UseContexts

copyright: https://creativecommons.org/licenses/by-nc-sa/4.0/

relatedArtifact

type: derived-from

label: data source

display: Figure 2C

citation: Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations [Journal Article]. Contributors: Francesco Rubino, David M Nathan, Robert H Eckel, Philip R Schauer, K George M M Alberti, Paul Z Zimmet, Stefano Del Prato, Linong Ji, Shaukat M Sadikot, William H Herman, Stephanie A Amiel, Lee M Kaplan, Gaspar Taroncher-Oldenburg, David E Cummings, Delegates of the 2nd Diabetes Surgery Summit. In: Diabetes care, PMID 27222544. Published June 2016. Available at: https://pubmed.ncbi.nlm.nih.gov/27222544/.

document

relatedArtifact

type: cite-as

citation: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Schauer 2012 (STAMPEDE) trial [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 47758. Revised 2022-05-29. Available at: https://fevir.net/resources/Evidence/47758. Computable resource at: https://fevir.net/resources/Evidence/47758.

description: Mean HbA1c at 12 months in Schauer 2012 was 6.5% in Surgery group (n = 99) and 7.5% in Medical/Lifestyle group (n = 41), mean difference -1.00% (95% CI -1.58% to -0.42%)

variableDefinition

VariableDefinitionVariableRoleCode: population

description: 140 obese patients with uncontrolled T2DM

note: population

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#population "population")

observed: : Schauer 2012 Trial Enrollment Group

variableDefinition

VariableDefinitionVariableRoleCode: exposure

VariableDefinitionComparatorCategory: medical treatment

description: Roux-en-Y Gastric Bypass or Sleeve Gastrectomy plus medical therapy vs. medical treatment (Medical therapy alone)

note: exposure

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#exposure "exposure")

observed: EvidenceVariable/172478: GroupAssignment: Roux-en-Y gastric bypass vs. medical treatment "GroupAssignment_Roux_en_Y_gastric_bypass_vs_medical_treatment"

variableDefinition

VariableDefinitionVariableRoleCode: outcome

description: HbA1c at 12 months

note: outcome

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#measuredVariable "measured variable")

observed: EvidenceVariable/173243: OutcomeVariable: HbA1c at 12 months "OutcomeVariable_HbA1c_at_12_months"

synthesisType: not applicable (StatisticSynthesisType#NotApplicable)

studyDesign: randomized assignment (Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide#SEVCO:01003)

statistic

description: mean difference -1.00% (95% CI -1.58% to -0.42%)

note: Mean HbA1c at 12 months in Schauer 2012 was 6.5% in Surgery group (n = 99) and 7.5% in Medical/Lifestyle group (n = 41)

statisticType: Mean Difference (StatisticStatisticType#0000457)

quantity: -1 % (Details: UCUM code % = '%')

SampleSizes

-	NumberOfParticipants	KnownDataCount
*	140	140

AttributeEstimates

-	Description	Type	Level	Range
*	95% CI -1.58% to -0.42%	Confidence interval (StatisticAttribute Estimate Type#C53324)	0.95	-1.58--0.42 %