Generated Narrative: Evidence

StructureDefinition Work Group: cds

url: https://fevir.net/resources/Evidence/47665

identifier: FEvIR Object Identifier: 47665

version: 1.0.0-ballot

name: ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Mingrone_2012_DIBASY_trial

title: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Mingrone 2012 (DIBASY) trial

status: active

date: 2022-05-29 11:06:42+0000

publisher: HL7 International / Clinical Decision Support

contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss

author: Brian S. Alper:

UseContexts

copyright: https://creativecommons.org/licenses/by-nc-sa/4.0/

relatedArtifact

type: derived-from

label: data source

display: Figure 2C

citation: Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations [Journal Article]. Contributors: Francesco Rubino, David M Nathan, Robert H Eckel, Philip R Schauer, K George M M Alberti, Paul Z Zimmet, Stefano Del Prato, Linong Ji, Shaukat M Sadikot, William H Herman, Stephanie A Amiel, Lee M Kaplan, Gaspar Taroncher-Oldenburg, David E Cummings, Delegates of the 2nd Diabetes Surgery Summit. In: Diabetes care, PMID 27222544. Published June 2016. Available at: https://pubmed.ncbi.nlm.nih.gov/27222544/.

document

relatedArtifact

type: cite-as

citation: ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Mingrone 2012 (DIBASY) trial [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 47665. Revised 2022-05-29. Available at: https://fevir.net/resources/Evidence/47665. Computable resource at: https://fevir.net/resources/Evidence/47665.

description: Mean HbA1c at 24 months in Mingrone 2012 was 5.65% in Surgery group (n = 20) and 7.69% in Medical/Lifestyle group (n = 20), mean difference -2.04% (95% CI -2.53% to -1.55%)

variableDefinition

VariableDefinitionVariableRoleCode: population

description: 60 patients aged 30-60 years with a body-mass index of 35 kg/m(2) or more and a history of type 2 diabetes lasting at least 5 years

note: population

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#population "population")

observed: Group/46117: DIBASY Trial Enrollment Group "StudyGroup_DIBASY_Trial_Enrollment_Group"

variableDefinition

VariableDefinitionVariableRoleCode: exposure

VariableDefinitionComparatorCategory: medical treatment

description: Roux-en-Y gastric bypass vs. medical treatment

note: exposure

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#exposure "exposure")

observed: EvidenceVariable/172478: GroupAssignment: Roux-en-Y gastric bypass vs. medical treatment "GroupAssignment_Roux_en_Y_gastric_bypass_vs_medical_treatment"

variableDefinition

VariableDefinitionVariableRoleCode: outcome

description: HbA1c at 24 months

note: outcome

variableRole: Use extension:variableRoleCode instead. (EvidenceVariableRole#measuredVariable "measured variable")

observed: EvidenceVariable/173246: OutcomeVariable: HbA1c at 24 months "OutcomeVariable_HbA1c_at_24_months"

synthesisType: not applicable (StatisticSynthesisType#NotApplicable)

studyDesign: randomized assignment (Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide#SEVCO:01003)

statistic

description: mean difference -2.04% (95% CI -2.53% to -1.55%)

note: Mean HbA1c at 24 months in Mingrone 2012 was 5.65% in Surgery group (n = 20) and 7.69% in Medical/Lifestyle group (n = 20)

statisticType: Mean Difference (StatisticStatisticType#0000457)

quantity: -2.04 % (Details: UCUM code % = '%')

SampleSizes

-	NumberOfParticipants	KnownDataCount
*	40	40

AttributeEstimates

-	Description	Type	Level	Range
*	95% CI -2.53% to -1.55%	Confidence interval (StatisticAttribute Estimate Type#C53324)	0.95	-2.53--1.55 %