Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot - ballot International flag

This page is part of the Evidence Based Medicine on FHIR Implementation Guide (v1.0.0-ballot: STU1 Ballot 1) based on FHIR (HL7® FHIR® Standard) v5.0.0. . For a full list of available versions, see the Directory of published versions

: NetEffectContribution: Treatment with opioids for Example for GIN 2022 - JSON Representation

Active as of 2023-12-17

Raw json | Download


{
  "resourceType" : "Evidence",
  "id" : "179590",
  "meta" : {
    "versionId" : "4",
    "lastUpdated" : "2023-12-08T13:32:44.405Z",
    "profile" : [
      🔗 "http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution"
    ]
  },
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Evidence</b><a name=\"179590\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Evidence &quot;179590&quot; Version &quot;4&quot; Updated &quot;2023-12-08 13:32:44+0000&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-net-effect-contribution.html\">NetEffectContribution</a></p></div><p><b>StructureDefinition Work Group</b>: cds</p><p><b>url</b>: <code>https://fevir.net/resources/Evidence/179590</code></p><p><b>identifier</b>: FEvIR Object Identifier:\u00a0179590</p><p><b>version</b>: 1.0.0-ballot</p><p><b>name</b>: NetEffectContribution_Treatment_with_opioids_for_Example_for_GIN_2022</p><p><b>title</b>: NetEffectContribution: Treatment with opioids for Example for GIN 2022</p><p><b>status</b>: active</p><p><b>date</b>: 2023-12-17 16:55:23+0000</p><p><b>publisher</b>: HL7 International / Clinical Decision Support</p><p><b>contact</b>: HL7 International / Clinical Decision Support: <a href=\"http://www.hl7.org/Special/committees/dss\">http://www.hl7.org/Special/committees/dss</a></p><p><b>author</b>: Brian S. Alper: </p><h3>UseContexts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Evidence Communication (Details: https://fevir.net/resources/CodeSystem/179423 code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')</td><td>ComparativeEvidence <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-179423.html\">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#ComparativeEvidence)</span></td></tr><tr><td style=\"display: none\">*</td><td>Evidence Communication (Details: https://fevir.net/resources/CodeSystem/179423 code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')</td><td>NetEffectContribution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-179423.html\">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#NetEffectContribution)</span></td></tr></table><p><b>copyright</b>: https://creativecommons.org/licenses/by-nc-sa/4.0/</p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Citation</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>cite-as</td><td>NetEffectContribution: Treatment with opioids for Example for GIN 2022 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179590. Revised 2023-12-04. Available at: https://fevir.net/resources/Evidence/179590. Computable resource at: https://fevir.net/resources/Evidence/179590.</td><td> </td></tr><tr><td style=\"display: none\">*</td><td>amended-with</td><td> </td><td><a href=\"ArtifactAssessment-104195.html\">ArtifactAssessment/104195: Outcome Importance Rating (default value 5) of Treatment with opioids</a></td></tr></table><p><b>description</b>: -0.24 (-0.32 to -0.16)</p><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: population</p><p><b>description</b>: Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n\u2009=\u20092109) with severe obesity assessed (221 patients excluded and 1888 patients included).</p><p><b>note</b>: population</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#population &quot;population&quot;)</span></p><p><b>observed</b>: <a href=\"Group-178427.html\">Group/178427: StudyGroup: Severely Obese Adults 2018 Norwegian Cohort</a> &quot;Severely_Obese_Adults_2018_Norwegian_Cohort&quot;</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: exposure</p><p><b>VariableDefinitionComparatorCategory</b>: no bariatric surgery</p><p><b>description</b>: comparison groups of bariatric surgery vs. no bariatric surgery</p><p><b>note</b>: exposure</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#exposure &quot;exposure&quot;)</span></p><p><b>observed</b>: <a href=\"EvidenceVariable-172427.html\">EvidenceVariable/172427: GroupAssignment: Bariatric Surgery vs. no bariatric surgery</a> &quot;GroupAssignment_Bariatric_Surgery_vs_no_bariatric_surgery&quot;</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: outcome</p><p><b>description</b>: Treatment with opioids</p><p><b>note</b>: outcome</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#measuredVariable &quot;measured variable&quot;)</span></p><p><b>observed</b>: <a href=\"EvidenceVariable-104119.html\">EvidenceVariable/104119: OutcomeVariable: Treatment with opioids</a> &quot;OutcomeVariable_Treatment_with_opioids&quot;</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: covariate</p><p><b>VariableDefinitionRoleSubtype</b>: Relative importance multiplier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-179423.html\">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#importance-multiplier)</span></p><p><b>description</b>: Relative Importance Multiplier</p><p><b>note</b>: covariate</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#confounder &quot;confounder&quot;)</span></p><p><b>observed</b>: <span>: Relative Importance Multiplier</span></p></blockquote><blockquote><p><b>statistic</b></p><p><b>description</b>: risk difference -0.24 (95% CI -0.32 to -0.16)</p><p><b>statisticType</b>: Risk Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-181513.html\">Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide</a>#STATO:0000424)</span></p><p><b>quantity</b>: -0.24</p><h3>AttributeEstimates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Description</b></td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>95% CI -0.32 to -0.16</td><td>confidence interval <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-181513.html\">Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide</a>#STATO:0000196)</span></td><td>0.95</td><td>-0.32--0.16</td></tr></table><h3>ModelCharacteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Net effect contribution analysis <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-181513.html\">Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide</a>#TBD:net-effect-contribution-analysis)</span></td></tr></table></blockquote></div>"
  },
  "extension" : [
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode" : "cds"
    }
  ],
  "url" : "https://fevir.net/resources/Evidence/179590",
  "identifier" : [
    {
      "type" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "ACSN",
            "display" : "Accession ID"
          }
        ],
        "text" : "FEvIR Object Identifier"
      },
      "system" : "https://fevir.net",
      "value" : "179590",
      "assigner" : {
        "display" : "Computable Publishing LLC"
      }
    }
  ],
  "version" : "1.0.0-ballot",
  "name" : "NetEffectContribution_Treatment_with_opioids_for_Example_for_GIN_2022",
  "title" : "NetEffectContribution: Treatment with opioids for Example for GIN 2022",
  "status" : "active",
  "date" : "2023-12-17T16:55:23+00:00",
  "publisher" : "HL7 International / Clinical Decision Support",
  "contact" : [
    {
      "name" : "HL7 International / Clinical Decision Support",
      "telecom" : [
        {
          "system" : "url",
          "value" : "http://www.hl7.org/Special/committees/dss"
        }
      ]
    }
  ],
  "author" : [
    {
      "name" : "Brian S. Alper"
    }
  ],
  "useContext" : [
    {
      "code" : {
        "system" : "https://fevir.net/resources/CodeSystem/179423",
        "code" : "evidence-communication",
        "display" : "Evidence Communication"
      },
      "valueCodeableConcept" : {
        "coding" : [
          {
            "system" : "https://fevir.net/resources/CodeSystem/179423",
            "code" : "ComparativeEvidence",
            "display" : "ComparativeEvidence"
          }
        ]
      }
    },
    {
      "code" : {
        "system" : "https://fevir.net/resources/CodeSystem/179423",
        "code" : "evidence-communication",
        "display" : "Evidence Communication"
      },
      "valueCodeableConcept" : {
        "coding" : [
          {
            "system" : "https://fevir.net/resources/CodeSystem/179423",
            "code" : "NetEffectContribution",
            "display" : "NetEffectContribution"
          }
        ]
      }
    }
  ],
  "copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "relatedArtifact" : [
    {
      "type" : "cite-as",
      "citation" : "NetEffectContribution: Treatment with opioids for Example for GIN 2022 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179590. Revised 2023-12-04. Available at: https://fevir.net/resources/Evidence/179590. Computable resource at: https://fevir.net/resources/Evidence/179590."
    },
    {
      "type" : "amended-with",
      "resourceReference" : {
        🔗 "reference" : "ArtifactAssessment/104195",
        "type" : "ArtifactAssessment",
        "display" : "Outcome Importance Rating (default value 5) of Treatment with opioids"
      }
    }
  ],
  "description" : "-0.24 (-0.32 to -0.16)",
  "variableDefinition" : [
    {
      "extension" : [
        {
          "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code",
          "valueCode" : "population"
        }
      ],
      "description" : "Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n\u2009=\u20092109) with severe obesity assessed (221 patients excluded and 1888 patients included).",
      "note" : [
        {
          "text" : "population"
        }
      ],
      "variableRole" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/variable-role",
            "code" : "population",
            "display" : "population"
          }
        ],
        "text" : "Use extension:variableRoleCode instead."
      },
      "observed" : {
        🔗 "reference" : "Group/178427",
        "type" : "Group",
        "display" : "StudyGroup: Severely Obese Adults 2018 Norwegian Cohort"
      }
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code",
          "valueCode" : "exposure"
        },
        {
          "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-comparator-category",
          "valueString" : "no bariatric surgery"
        }
      ],
      "description" : "comparison groups of bariatric surgery vs. no bariatric surgery",
      "note" : [
        {
          "text" : "exposure"
        }
      ],
      "variableRole" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/variable-role",
            "code" : "exposure",
            "display" : "exposure"
          }
        ],
        "text" : "Use extension:variableRoleCode instead."
      },
      "observed" : {
        🔗 "reference" : "EvidenceVariable/172427",
        "type" : "EvidenceVariable",
        "display" : "GroupAssignment: Bariatric Surgery vs. no bariatric surgery"
      }
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code",
          "valueCode" : "outcome"
        }
      ],
      "description" : "Treatment with opioids",
      "note" : [
        {
          "text" : "outcome"
        }
      ],
      "variableRole" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/variable-role",
            "code" : "measuredVariable",
            "display" : "measured variable"
          }
        ],
        "text" : "Use extension:variableRoleCode instead."
      },
      "observed" : {
        🔗 "reference" : "EvidenceVariable/104119",
        "type" : "EvidenceVariable",
        "display" : "OutcomeVariable: Treatment with opioids"
      }
    },
    {
      "extension" : [
        {
          "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code",
          "valueCode" : "covariate"
        },
        {
          "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-role-subtype",
          "valueCodeableConcept" : {
            "coding" : [
              {
                "system" : "https://fevir.net/resources/CodeSystem/179423",
                "code" : "importance-multiplier",
                "display" : "Relative importance multiplier"
              }
            ]
          }
        }
      ],
      "description" : "Relative Importance Multiplier",
      "note" : [
        {
          "text" : "covariate"
        }
      ],
      "variableRole" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/variable-role",
            "code" : "confounder",
            "display" : "confounder"
          }
        ],
        "text" : "Use extension:variableRoleCode instead."
      },
      "observed" : {
        "display" : "Relative Importance Multiplier"
      }
    }
  ],
  "statistic" : [
    {
      "description" : "risk difference -0.24 (95% CI -0.32 to -0.16)",
      "statisticType" : {
        "coding" : [
          {
            "system" : "https://fevir.net/resources/CodeSystem/181513",
            "code" : "STATO:0000424",
            "display" : "Risk Difference"
          }
        ]
      },
      "quantity" : {
        "value" : -0.24
      },
      "attributeEstimate" : [
        {
          "description" : "95% CI -0.32 to -0.16",
          "type" : {
            "coding" : [
              {
                "system" : "https://fevir.net/resources/CodeSystem/181513",
                "code" : "STATO:0000196",
                "display" : "confidence interval"
              }
            ]
          },
          "level" : 0.95,
          "range" : {
            "low" : {
              "value" : -0.32
            },
            "high" : {
              "value" : -0.16
            }
          }
        }
      ],
      "modelCharacteristic" : [
        {
          "code" : {
            "coding" : [
              {
                "system" : "https://fevir.net/resources/CodeSystem/181513",
                "code" : "TBD:net-effect-contribution-analysis",
                "display" : "Net effect contribution analysis"
              }
            ]
          }
        }
      ]
    }
  ]
}