26028518 Androgen deprivation therapy plus docetaxel and estramustine versus androgen deprivation therapy alone for high-risk localised prostate cancer (GETUG 12): a phase 3 randomised controlled trial. - JSON Representation - Evidence Based Medicine on FHIR Implementation Guide v1.0.0-ballot

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: 26028518 Androgen deprivation therapy plus docetaxel and estramustine versus androgen deprivation therapy alone for high-risk localised prostate cancer (GETUG 12): a phase 3 randomised controlled trial. - JSON Representation

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    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Citation</b><a name=\"179621\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Citation &quot;179621&quot; Version &quot;1&quot; Updated &quot;2023-11-26 22:35:14+0000&quot; </p></div><p><b>StructureDefinition Work Group</b>: cds</p><p><b>url</b>: <code>https://fevir.net/resources/Citation/179621</code></p><p><b>identifier</b>: FEvIR Object Identifier:\u00a0179621, id:\u00a026028518</p><p><b>version</b>: 1.0.0-ballot</p><p><b>title</b>: 26028518 Androgen deprivation therapy plus docetaxel and estramustine versus androgen deprivation therapy alone for high-risk localised prostate cancer (GETUG 12): a phase 3 randomised controlled trial.</p><p><b>status</b>: active</p><p><b>date</b>: 2023-12-17 16:55:23+0000</p><p><b>publisher</b>: HL7 International / Clinical Decision Support</p><p><b>contact</b>: HL7 International / Clinical Decision Support: <a href=\"http://www.hl7.org/Special/committees/dss\">http://www.hl7.org/Special/committees/dss</a></p><p><b>description</b>: This Citation Resource is referenced in an example for the EBMonFHIR Implementation Guide.</p><h3>UseContexts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>FEvIR Platform Use (Details: http://hl7.org/fhir/citation-classification-type code fevir-platform-use = 'FEvIR Platform Use', stated as 'FEvIR Platform Use')</td><td>Medline Base <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-artifact-classifier.html\">Citation Artifact Classifier</a>#medline-base)</span></td></tr></table><p><b>jurisdiction</b>: World <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (m49.htm#001)</span></p><p><b>copyright</b>: https://creativecommons.org/licenses/by-nc-sa/4.0/</p><p><b>approvalDate</b>: 2015-09-28</p><p><b>lastReviewDate</b>: 2022-03-30</p><p><b>author</b>: Computable Publishing®: MEDLINE-to-FEvIR Converter: </p><blockquote><p><b>classification</b></p><p><b>type</b>: Citation Source <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-classification-type.html\">Citation Classification Type</a>#citation-source)</span></p><p><b>classifier</b>: MEDLINE <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: MEDLINE Citation Owner <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-classification-type.html\">Citation Classification Type</a>#medline-owner)</span></p><p><b>classifier</b>: National Library of Medicine, Index Section <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (elements_descriptions.html#owner_value#NLM)</span></p></blockquote><p><b>currentState</b>: Medline Citation Status of Medline <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-status-type.html\">Citation Status Type</a>#medline-medline)</span>, PubMed PublicationStatus of ppublish <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-status-type.html\">Citation Status Type</a>#pubmed-publication-status-ppublish)</span></p><blockquote><p><b>statusDate</b></p><p><b>activity</b>: PubMed Pubstatus of Received <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-status-type.html\">Citation Status Type</a>#pubmed-pubstatus-received)</span></p><p><b>period</b>: ?? --&gt; 2015-04-15</p></blockquote><blockquote><p><b>statusDate</b></p><p><b>activity</b>: PubMed Pubstatus of Revised <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-status-type.html\">Citation Status Type</a>#pubmed-pubstatus-revised)</span></p><p><b>period</b>: ?? --&gt; 2015-05-06</p></blockquote><blockquote><p><b>statusDate</b></p><p><b>activity</b>: PubMed Pubstatus of Accepted <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-status-type.html\">Citation Status Type</a>#pubmed-pubstatus-accepted)</span></p><p><b>period</b>: ?? --&gt; 2015-05-08</p></blockquote><blockquote><p><b>statusDate</b></p><p><b>activity</b>: PubMed Pubstatus of Entrez <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-status-type.html\">Citation Status Type</a>#pubmed-pubstatus-entrez)</span></p><p><b>period</b>: ?? --&gt; 2015-06-02 06:00:00+0000</p></blockquote><blockquote><p><b>statusDate</b></p><p><b>activity</b>: PubMed Pubstatus of Pubmed <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-status-type.html\">Citation Status Type</a>#pubmed-pubstatus-pubmed)</span></p><p><b>period</b>: ?? --&gt; 2015-06-02 06:00:00+0000</p></blockquote><blockquote><p><b>statusDate</b></p><p><b>activity</b>: PubMed Pubstatus of Medline <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-status-type.html\">Citation Status Type</a>#pubmed-pubstatus-medline)</span></p><p><b>period</b>: ?? --&gt; 2015-09-29 06:00:00+0000</p></blockquote><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: id:\u00a026028518, id:\u00a010.1016/S1470-2045(15)00011-X, pii:\u00a0S1470-2045(15)00011-X</p><p><b>relatedIdentifier</b>: id:\u00a0NCT00055731</p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Language</b></td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td>Primary title <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-title-type.html\">Title Type</a>#primary)</span></td><td>English <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ietf3066.html\">Tags for the Identification of Languages</a>#en)</span></td><td>Androgen deprivation therapy plus docetaxel and estramustine versus androgen deprivation therapy alone for high-risk localised prostate cancer (GETUG 12): a phase 3 randomised controlled trial.</td></tr></table><h3>Abstracts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td><td><b>Copyright</b></td></tr><tr><td style=\"display: none\">*</td><td>**BACKGROUND:** Early risk-stratified chemotherapy is a standard treatment for breast, colorectal, and lung cancers, but not for high-risk localised prostate cancer. Combined docetaxel and estramustine improves survival in patients with castration-resistant prostate cancer. We assessed the effects of combined docetaxel and estramustine on relapse in patients with high-risk localised prostate cancer.\n**METHODS:** We did this randomised phase 3 trial at 26 hospitals in France. We enrolled patients with treatment-naive prostate cancer and at least one risk factor (ie, stage T3-T4 disease, Gleason score of ≥8, prostate-specific antigen concentration &amp;gt;20 ng/mL, or pathological node-positive). All patients underwent a staging pelvic lymph node dissection. Patients were randomly assigned (1:1) to either androgen deprivation therapy (ADT; goserelin 10·8 mg every 3 months for 3 years) plus four cycles of docetaxel on day 2 at a dose of 70 mg/m(2) and estramustine 10 mg/kg per day on days 1-5, every 3 weeks, or ADT only. The randomisation was done centrally by computer, stratified by risk factor. Local treatment was administered at 3 months. Neither patients nor investigators were masked to treatment allocation. The primary endpoint was relapse-free survival in the intention-to-treat population. Follow-up for other endpoints is ongoing. This study is registered with ClinicalTrials.gov, number NCT00055731.\n**FINDINGS:** We randomly assigned 207 patients to the ADT plus docetaxel and estramustine group and 206 to the ADT only group. Median follow-up was 8·8 years (IQR 8·1-9·7). 88 (43%) of 207 patients in the ADT plus docetaxel and estramustine group had an event (relapse or death) versus 111 (54%) of 206 in the ADT only group. 8-year relapse-free survival was 62% (95% CI 55-69) in the ADT plus docetaxel and estramustine group versus 50% (44-57) in the ADT only group (adjusted hazard ratio [HR] 0·71, 95% CI 0·54-0·94, p=0·017). Of patients who were treated with radiotherapy and had data available, 31 (21%) of 151 in the ADT plus docetaxel and estramustine group versus 26 (18%) of 143 in the ADT only group reported a grade 2 or higher long-term side-effect (p=0·61). We recorded no excess second cancers (26 [13%] of 207 vs 22 [11%] of 206; p=0·57), and there were no treatment-related deaths.\n**INTERPRETATION:** Docetaxel-based chemotherapy improves relapse-free survival in patients with high-risk localised prostate cancer. Longer follow-up is needed to assess whether this benefit translates into improved metastasis-free survival and overall survival.\n**FUNDING:** Ligue Contre le Cancer, Sanofi-Aventis, AstraZeneca, Institut National du Cancer.</td><td>Copyright © 2015 Elsevier Ltd. All rights reserved.</td></tr></table><blockquote><p><b>relatesTo</b></p><p><b>type</b>: comment-in</p><p><b>classifier</b>: Comment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016420)</span></p><p><b>citation</b>: Lancet Oncol. 2015 Jul;16(7):741-2</p><h3>Documents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://pubmed.ncbi.nlm.nih.gov/26028517/\">https://pubmed.ncbi.nlm.nih.gov/26028517/</a></td></tr></table><p><b>resourceReference</b>: <span>id:\u00a026028517</span></p></blockquote><blockquote><p><b>relatesTo</b></p><p><b>type</b>: comment-in</p><p><b>classifier</b>: Comment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016420)</span></p><p><b>citation</b>: Nat Rev Urol. 2015 Jul;12(7):358</p><h3>Documents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://pubmed.ncbi.nlm.nih.gov/26077993/\">https://pubmed.ncbi.nlm.nih.gov/26077993/</a></td></tr></table><p><b>resourceReference</b>: <span>id:\u00a026077993</span></p></blockquote><blockquote><p><b>relatesTo</b></p><p><b>type</b>: comment-in</p><p><b>classifier</b>: Comment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016420)</span></p><p><b>citation</b>: Eur Urol. 2015 Dec;68(6):1098-9</p><h3>Documents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://pubmed.ncbi.nlm.nih.gov/26545569/\">https://pubmed.ncbi.nlm.nih.gov/26545569/</a></td></tr></table><p><b>resourceReference</b>: <span>id:\u00a026545569</span></p></blockquote><blockquote><p><b>relatesTo</b></p><p><b>type</b>: comment-in</p><p><b>classifier</b>: Comment <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016420)</span></p><p><b>citation</b>: Nat Rev Clin Oncol. 2015 Dec;12(12):687-8</p><h3>Documents</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://pubmed.ncbi.nlm.nih.gov/26552950/\">https://pubmed.ncbi.nlm.nih.gov/26552950/</a></td></tr></table><p><b>resourceReference</b>: <span>id:\u00a026552950</span></p></blockquote><blockquote><p><b>publicationForm</b></p><h3>PublishedIns</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Identifier</b></td><td><b>Title</b></td><td><b>PublisherLocation</b></td></tr><tr><td style=\"display: none\">*</td><td>Periodical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-published-in-type.html\">Published In Type</a>#D020492)</span></td><td>Electronic ISSN Type:\u00a01474-5488, ISOAbbreviation:\u00a0Lancet Oncol, ISSN Linking:\u00a01470-2045, Medline Title Abbreviation:\u00a0Lancet Oncol, NLM Unique ID:\u00a0100957246</td><td>The Lancet. Oncology</td><td>England</td></tr></table><p><b>citedMedium</b>: Internet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-medium.html\">Cited Medium</a>#internet)</span></p><p><b>volume</b>: 16</p><p><b>issue</b>: 7</p><p><b>articleDate</b>: 2015-07</p><p><b>publicationDateText</b>: 2015-Jul</p><p><b>language</b>: English <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ietf3066.html\">Tags for the Identification of Languages</a>#en)</span></p><p><b>pageString</b>: 787-94</p></blockquote><blockquote><p><b>publicationForm</b></p><p><b>citedMedium</b>: Internet without issue <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-medium.html\">Cited Medium</a>#internet-without-issue)</span></p><p><b>articleDate</b>: 2015-05-28</p></blockquote><blockquote><p><b>webLocation</b></p><p><b>classifier</b>: Abstract <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-artifact-url-classifier.html\">Artifact Url Classifier</a>#abstract)</span></p><p><b>url</b>: <a href=\"https://pubmed.ncbi.nlm.nih.gov/26028518/\">https://pubmed.ncbi.nlm.nih.gov/26028518/</a></p></blockquote><blockquote><p><b>webLocation</b></p><p><b>classifier</b>: DOI Based <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-artifact-url-classifier.html\">Artifact Url Classifier</a>#doi-based)</span></p><p><b>url</b>: <a href=\"https://doi.org/10.1016/S1470-2045(15)00011-X\">https://doi.org/10.1016/S1470-2045(15)00011-X</a></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: Publishing Model <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#publishing-model)</span></p><p><b>classifier</b>: Print Electronic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-artifact-classifier.html\">Citation Artifact Classifier</a>#Print-Electronic)</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: Chemical <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#chemical)</span></p><p><b>classifier</b>: Androgen Antagonists <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D000726)</span>, Taxoids <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D043823)</span>, Docetaxel <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (chemical-substances#15H5577CQD; #D000077143)</span>, Estramustine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (chemical-substances#35LT29625A; #D004961)</span>, Prostate-Specific Antigen <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (chemical-substances#EC 3.4.21.77; #D017430)</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: MeSH Heading <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading)</span></p><p><b>artifactAssessment</b>: <a name=\"meshHeading0\"> </a></p><blockquote><p/><p><a name=\"meshHeading0\"> </a></p><p><b>artifact</b>: <a href=\"#\">#</a></p><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Aged <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D000368)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Androgen Antagonists <span style=\"background: LightGoldenRodYellow; 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margin: 4px; border: 1px solid khaki\"> (#D000971)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: therapeutic use <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000627)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Disease-Free Survival <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D018572)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Docetaxel <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D000077143)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Dose-Response Relationship, Drug <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D004305)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Drug Administration Schedule <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D004334)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Estramustine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D004961)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: administration &amp; dosage <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000008)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Follow-Up Studies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D005500)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: France <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D005602)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Humans <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D006801)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Kaplan-Meier Estimate <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D053208)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Male <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D008297)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Maximum Tolerated Dose <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D020714)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Middle Aged <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D008875)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Neoplasm Invasiveness <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D009361)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: pathology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000473)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Neoplasm Recurrence, Local <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D009364)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: epidemiology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000453)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: pathology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000473)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Neoplasm Staging <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D009367)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Proportional Hazards Models <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016016)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Prostate-Specific Antigen <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D017430)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000097)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Prostatic Neoplasms <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D011471)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: drug therapy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000188)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: mortality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000401)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: pathology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000473)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Survival Analysis <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016019)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Taxoids <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D043823)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: administration &amp; dosage <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000008)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Treatment Outcome <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016896)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: Publication Type <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#publication-type)</span></p><p><b>classifier</b>: Clinical Trial, Phase III <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D017428)</span>, Comparative Study <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D003160)</span>, Journal Article <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016428)</span>, Multicenter Study <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016448)</span>, Randomized Controlled Trial <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016449)</span>, Research Support, Non-U.S. Gov't <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D013485)</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: Knowledge Artifact Type <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#knowledge-artifact-type)</span></p><p><b>classifier</b>: Journal Article <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-artifact-classifier.html\">Citation Artifact Classifier</a>#D016428)</span></p><p><b>artifactAssessment</b>: <span>: Classifier added by Computable Publishing LLC</span></p></blockquote><blockquote><p><b>classification</b></p><p><b>type</b>: Citation Subset <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#citation-subset)</span></p><p><b>classifier</b>: IM <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (elements_descriptions.html#citationsubset#IM)</span></p></blockquote><blockquote><p><b>contributorship</b></p><p><b>complete</b>: true</p><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author0\"> </a></p><blockquote><p/><p><a name=\"author0\"> </a></p><p><b>name</b>: Karim Fizazi </p></blockquote><p><b>forenameInitials</b>: K</p><p><b>affiliation</b>: <span>: Institut Gustave Roussy, Villejuif, France. Electronic address: karim.fizazi@gustaveroussy.fr.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author1\"> </a></p><blockquote><p/><p><a name=\"author1\"> </a></p><p><b>name</b>: Laura Faivre </p></blockquote><p><b>forenameInitials</b>: L</p><p><b>affiliation</b>: <span>: Institut Gustave Roussy, Villejuif, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author2\"> </a></p><blockquote><p/><p><a name=\"author2\"> </a></p><p><b>name</b>: François Lesaunier </p></blockquote><p><b>forenameInitials</b>: F</p><p><b>affiliation</b>: <span>: Centre François Baclesse, Caen, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author3\"> </a></p><blockquote><p/><p><a name=\"author3\"> </a></p><p><b>name</b>: Remy Delva </p></blockquote><p><b>forenameInitials</b>: R</p><p><b>affiliation</b>: <span>: Institut de Cancérologie de l'Ouest, Angers, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author4\"> </a></p><blockquote><p/><p><a name=\"author4\"> </a></p><p><b>name</b>: Gwenaëlle Gravis </p></blockquote><p><b>forenameInitials</b>: G</p><p><b>affiliation</b>: <span>: Institut Paoli Calmettes, Marseille, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author5\"> </a></p><blockquote><p/><p><a name=\"author5\"> </a></p><p><b>name</b>: Frédéric Rolland </p></blockquote><p><b>forenameInitials</b>: F</p><p><b>affiliation</b>: <span>: Institut de Cancérologie de l'Ouest, Nantes, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author6\"> </a></p><blockquote><p/><p><a name=\"author6\"> </a></p><p><b>name</b>: Frank Priou </p></blockquote><p><b>forenameInitials</b>: F</p><p><b>affiliation</b>: <span>: Centre Hospitalier Départemental, La Roche-sur-Yon, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author7\"> </a></p><blockquote><p/><p><a name=\"author7\"> </a></p><p><b>name</b>: Jean-Marc Ferrero </p></blockquote><p><b>forenameInitials</b>: JM</p><p><b>affiliation</b>: <span>: Centre Antoine Lacassagne, Nice, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author8\"> </a></p><blockquote><p/><p><a name=\"author8\"> </a></p><p><b>name</b>: Nadine Houede </p></blockquote><p><b>forenameInitials</b>: N</p><p><b>affiliation</b>: <span>: Centre Hospitalier de Nimes, Nimes, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author9\"> </a></p><blockquote><p/><p><a name=\"author9\"> </a></p><p><b>name</b>: Loïc Mourey </p></blockquote><p><b>forenameInitials</b>: L</p><p><b>affiliation</b>: <span>: Institut Claudius Regaud, Toulouse, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author10\"> </a></p><blockquote><p/><p><a name=\"author10\"> </a></p><p><b>name</b>: Christine Theodore </p></blockquote><p><b>forenameInitials</b>: C</p><p><b>affiliation</b>: <span>: Hôpital Foch, Paris, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author11\"> </a></p><blockquote><p/><p><a name=\"author11\"> </a></p><p><b>name</b>: Ivan Krakowski </p></blockquote><p><b>forenameInitials</b>: I</p><p><b>affiliation</b>: <span>: Centre Alexis Vautrin, Nancy, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author12\"> </a></p><blockquote><p/><p><a name=\"author12\"> </a></p><p><b>name</b>: Jean-François Berdah </p></blockquote><p><b>forenameInitials</b>: JF</p><p><b>affiliation</b>: <span>: Clinique Sainte-Marguerite, Hyères, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author13\"> </a></p><blockquote><p/><p><a name=\"author13\"> </a></p><p><b>name</b>: Marjorie Baciuchka </p></blockquote><p><b>forenameInitials</b>: M</p><p><b>affiliation</b>: <span>: Centre Hospitalier La Timone, Marseille, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author14\"> </a></p><blockquote><p/><p><a name=\"author14\"> </a></p><p><b>name</b>: Brigitte Laguerre </p></blockquote><p><b>forenameInitials</b>: B</p><p><b>affiliation</b>: <span>: Centre Eugène Marquis, Rennes, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author15\"> </a></p><blockquote><p/><p><a name=\"author15\"> </a></p><p><b>name</b>: Aude Fléchon </p></blockquote><p><b>forenameInitials</b>: A</p><p><b>affiliation</b>: <span>: Centre Léon Bérard, Lyon, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author16\"> </a></p><blockquote><p/><p><a name=\"author16\"> </a></p><p><b>name</b>: Alain Ravaud </p></blockquote><p><b>forenameInitials</b>: A</p><p><b>affiliation</b>: <span>: Hôpital Saint-André, Bordeaux, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author17\"> </a></p><blockquote><p/><p><a name=\"author17\"> </a></p><p><b>name</b>: Isabelle Cojean-Zelek </p></blockquote><p><b>forenameInitials</b>: I</p><p><b>affiliation</b>: <span>: Groupe Hospitalier Diaconesses Croix Saint-Simon, Paris, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author18\"> </a></p><blockquote><p/><p><a name=\"author18\"> </a></p><p><b>name</b>: Stéphane Oudard </p></blockquote><p><b>forenameInitials</b>: S</p><p><b>affiliation</b>: <span>: Hôpital Européen Georges Pompidou, Paris, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author19\"> </a></p><blockquote><p/><p><a name=\"author19\"> </a></p><p><b>name</b>: Jean-Luc Labourey </p></blockquote><p><b>forenameInitials</b>: JL</p><p><b>affiliation</b>: <span>: CHU Dupuytren, Limoges, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author20\"> </a></p><blockquote><p/><p><a name=\"author20\"> </a></p><p><b>name</b>: Paule Chinet-Charrot </p></blockquote><p><b>forenameInitials</b>: P</p><p><b>affiliation</b>: <span>: Centre Henri Becquerel, Rouen, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author21\"> </a></p><blockquote><p/><p><a name=\"author21\"> </a></p><p><b>name</b>: Eric Legouffe </p></blockquote><p><b>forenameInitials</b>: E</p><p><b>affiliation</b>: <span>: Centre Médical Oncogard, Nimes, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author22\"> </a></p><blockquote><p/><p><a name=\"author22\"> </a></p><p><b>name</b>: Jean-Léon Lagrange </p></blockquote><p><b>forenameInitials</b>: JL</p><p><b>affiliation</b>: <span>: Hôpital Henri-Mondor, Créteil, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author23\"> </a></p><blockquote><p/><p><a name=\"author23\"> </a></p><p><b>name</b>: Claude Linassier </p></blockquote><p><b>forenameInitials</b>: C</p><p><b>affiliation</b>: <span>: Hôpital Bretonneau, Tours, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author24\"> </a></p><blockquote><p/><p><a name=\"author24\"> </a></p><p><b>name</b>: Gaël Deplanque </p></blockquote><p><b>forenameInitials</b>: G</p><p><b>affiliation</b>: <span>: Hôpital Saint-Joseph, Paris, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author25\"> </a></p><blockquote><p/><p><a name=\"author25\"> </a></p><p><b>name</b>: Philippe Beuzeboc </p></blockquote><p><b>forenameInitials</b>: P</p><p><b>affiliation</b>: <span>: Institut Curie, Paris, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author26\"> </a></p><blockquote><p/><p><a name=\"author26\"> </a></p><p><b>name</b>: Jean-Louis Davin </p></blockquote><p><b>forenameInitials</b>: JL</p><p><b>affiliation</b>: <span>: Clinique Sainte-Catherine, Avignon, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author27\"> </a></p><blockquote><p/><p><a name=\"author27\"> </a></p><p><b>name</b>: Anne-Laure Martin </p></blockquote><p><b>forenameInitials</b>: AL</p><p><b>affiliation</b>: <span>: Unicancer, Paris, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author28\"> </a></p><blockquote><p/><p><a name=\"author28\"> </a></p><p><b>name</b>: Muriel Habibian </p></blockquote><p><b>forenameInitials</b>: M</p><p><b>affiliation</b>: <span>: Unicancer, Paris, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author29\"> </a></p><blockquote><p/><p><a name=\"author29\"> </a></p><p><b>name</b>: Agnès Laplanche </p></blockquote><p><b>forenameInitials</b>: A</p><p><b>affiliation</b>: <span>: Institut Gustave Roussy, Villejuif, France.</span></p></blockquote><blockquote><p><b>entry</b></p><p><b>contributor</b>: <a name=\"author30\"> </a></p><blockquote><p/><p><a name=\"author30\"> </a></p><p><b>name</b>: Stéphane Culine </p></blockquote><p><b>forenameInitials</b>: S</p><p><b>affiliation</b>: <span>: Hôpital Saint-Louis, Paris, France.</span></p></blockquote></blockquote></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author0</b><a name=\"author0\"> </a></p><p><b>name</b>: Karim Fizazi </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author1</b><a name=\"author1\"> </a></p><p><b>name</b>: Laura Faivre </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author2</b><a name=\"author2\"> </a></p><p><b>name</b>: François Lesaunier </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author3</b><a name=\"author3\"> </a></p><p><b>name</b>: Remy Delva </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author4</b><a name=\"author4\"> </a></p><p><b>name</b>: Gwenaëlle Gravis </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author5</b><a name=\"author5\"> </a></p><p><b>name</b>: Frédéric Rolland </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author6</b><a name=\"author6\"> </a></p><p><b>name</b>: Frank Priou </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author7</b><a name=\"author7\"> </a></p><p><b>name</b>: Jean-Marc Ferrero </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author8</b><a name=\"author8\"> </a></p><p><b>name</b>: Nadine Houede </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author9</b><a name=\"author9\"> </a></p><p><b>name</b>: Loïc Mourey </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author10</b><a name=\"author10\"> </a></p><p><b>name</b>: Christine Theodore </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author11</b><a name=\"author11\"> </a></p><p><b>name</b>: Ivan Krakowski </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author12</b><a name=\"author12\"> </a></p><p><b>name</b>: Jean-François Berdah </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author13</b><a name=\"author13\"> </a></p><p><b>name</b>: Marjorie Baciuchka </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author14</b><a name=\"author14\"> </a></p><p><b>name</b>: Brigitte Laguerre </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author15</b><a name=\"author15\"> </a></p><p><b>name</b>: Aude Fléchon </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author16</b><a name=\"author16\"> </a></p><p><b>name</b>: Alain Ravaud </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author17</b><a name=\"author17\"> </a></p><p><b>name</b>: Isabelle Cojean-Zelek </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author18</b><a name=\"author18\"> </a></p><p><b>name</b>: Stéphane Oudard </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author19</b><a name=\"author19\"> </a></p><p><b>name</b>: Jean-Luc Labourey </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author20</b><a name=\"author20\"> </a></p><p><b>name</b>: Paule Chinet-Charrot </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author21</b><a name=\"author21\"> </a></p><p><b>name</b>: Eric Legouffe </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author22</b><a name=\"author22\"> </a></p><p><b>name</b>: Jean-Léon Lagrange </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author23</b><a name=\"author23\"> </a></p><p><b>name</b>: Claude Linassier </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author24</b><a name=\"author24\"> </a></p><p><b>name</b>: Gaël Deplanque </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author25</b><a name=\"author25\"> </a></p><p><b>name</b>: Philippe Beuzeboc </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author26</b><a name=\"author26\"> </a></p><p><b>name</b>: Jean-Louis Davin </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author27</b><a name=\"author27\"> </a></p><p><b>name</b>: Anne-Laure Martin </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author28</b><a name=\"author28\"> </a></p><p><b>name</b>: Muriel Habibian </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author29</b><a name=\"author29\"> </a></p><p><b>name</b>: Agnès Laplanche </p></blockquote><hr/><blockquote><p><b>Generated Narrative: Practitioner #author30</b><a name=\"author30\"> </a></p><p><b>name</b>: Stéphane Culine </p></blockquote><hr/><blockquote><p><b>Generated Narrative: ArtifactAssessment #meshHeading0</b><a name=\"meshHeading0\"> </a></p><p><b>artifact</b>: <a href=\"#\">#</a></p><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Aged <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D000368)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Androgen Antagonists <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D000726)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: therapeutic use <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000627)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Antineoplastic Combined Chemotherapy Protocols <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D000971)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: therapeutic use <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000627)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Disease-Free Survival <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D018572)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Docetaxel <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D000077143)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Dose-Response Relationship, Drug <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D004305)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Drug Administration Schedule <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D004334)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Estramustine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D004961)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: administration &amp; dosage <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000008)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Follow-Up Studies <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D005500)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: France <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D005602)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Humans <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D006801)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Kaplan-Meier Estimate <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D053208)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Male <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D008297)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Maximum Tolerated Dose <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D020714)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Middle Aged <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D008875)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Neoplasm Invasiveness <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D009361)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: pathology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000473)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Neoplasm Recurrence, Local <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D009364)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: epidemiology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000453)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: pathology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000473)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Neoplasm Staging <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D009367)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Proportional Hazards Models <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016016)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Prostate-Specific Antigen <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D017430)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: blood <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000097)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Prostatic Neoplasms <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D011471)</span></p><p><b>freeToShare</b>: true</p><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: drug therapy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000188)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: mortality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000401)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>classifier</b>: pathology <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#Q000473)</span></p><blockquote><p><b>component</b></p></blockquote></blockquote></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Survival Analysis <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016019)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: classifier</p><p><b>type</b>: components (if present) include qualifier codings <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Taxoids <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 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solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#mesh-heading &quot;MeSH heading&quot;)</span></p><p><b>classifier</b>: Treatment Outcome <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (#D016896)</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>qualifier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>is not a major topic <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td></tr></table></blockquote></blockquote></div>"
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