This page is part of the HL7 FHIR Implementation Guide: minimal Common Oncology Data Elements (mCODE) Release 1 - US Realm | STU1 (v0.9.1: STU 1 Ballot 1) based on FHIR R4. The current version which supercedes this version is 2.0.0. For a full list of available versions, see the Directory of published versions

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• XML
• JSON
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Example: mCODEGeneticVariantTestedExample01

{
  "resourceType" : "Observation",
  "id" : "mCODEGeneticVariantTestedExample01",
  "meta" : {
    "profile" : [
      "http://hl7.org/fhir/us/mcode/StructureDefinition/onco-core-GeneticVariantTested"
    ]
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>*** mCODE Example: Genetic Mutation Test Result ***</b></p><p><b>Name</b>: John B. Anyperson </p><p><b>MRN</b>: m123 </p><p><b>Observation date</b>: 04/01/19 </p><p><b>Gene studied [ID]</b>: STK11</p><p><b>Gene variant Description</b>: NM_000455.4(STK11):c.921-1G>C </p><p><b>Gene variant presence</b>: DETECTED</p></div>"
  },
  "extension" : [
    {
      "extension" : [
        {
          "url" : "http://hl7.org/fhir/us/mcode/StructureDefinition/onco-core-VariantHGVSName-extension",
          "valueString" : "NM_000455.4:c.921-1G>C"
        },
        {
          "url" : "http://hl7.org/fhir/us/mcode/StructureDefinition/onco-core-VariantIdentifier-extension",
          "valueCodeableConcept" : {
            "coding" : [
              {
                "system" : "http://www.genenames.org/",
                "code" : "HGNC:11389",
                "display" : "STK11"
              }
            ]
          }
        },
        {
          "url" : "http://hl7.org/fhir/us/mcode/StructureDefinition/onco-core-VariantDescription-extension",
          "valueString" : "NM_000455.4:c.921-1G>C"
        }
      ],
      "url" : "http://hl7.org/fhir/us/mcode/StructureDefinition/onco-core-VariantTested-extension"
    }
  ],
  "status" : "final",
  "category" : [
    {
      "coding" : [
        {
          "system" : "http://terminology.hl7.org/CodeSystem/observation-category",
          "code" : "laboratory",
          "display" : "Laboratory"
        }
      ]
    }
  ],
  "code" : {
    "coding" : [
      {
        "system" : "http://loinc.org",
        "code" : "41103-3",
        "display" : "Gene XXX mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"
      }
    ]
  },
  "subject" : {
    "reference" : "Patient/mCODEPatientExample01",
    "display" : "John B. Anyperson"
  },
  "effectiveDateTime" : "2019-04-01",
  "valueCodeableConcept" : {
    "coding" : [
      {
        "system" : "http://snomed.info/sct",
        "code" : "10828004",
        "display" : "Positive (qualifier value)"
      }
    ]
  },
  "method" : {
    "coding" : [
      {
        "system" : "http://ncit.nci.nih.gov",
        "code" : "C101293",
        "display" : "Next Generation Sequencing"
      }
    ]
  }
}