Anatomical location or specimen further detailing directionality. Codes are from NCI

Codes that describe normal and pathologic anatomic systems, regions, cavities, and spaces.

The method with which breast cancer was detected.

Histologic types of breast carcinomas, including invasive carcinoma and ductal carcinoma in situ. Codes are drawn from SNOMED CT; local codes are used where SNOMED CT codes are unavailable. The codes are intended to match the scope of breast carcinoma histologic types specified in ICD-O-3. Additional SNOMED CT codes may be appropriate to include in this value set. We are requesting feedback on the perceived need to request SNOMED CT codes to represent the histologic types currently represented by local codes.

The regional lymph node locations

Topography of the breast. Codes are drawn from SNOMED CT and can be regarded as equivalent to ICD-O-3 topography codes.

The surgical method used to obtain the tissue sample.

The type of specimen obtained from the breast. Codes are drawn from SNOMED CT where available. Local codes are used where Snomed codes are currently unavailable.

The relative direction of an object described using the analogy of a 12-hour clock to describe angles and directions. One imagines a clock face lying either upright or flat in front of oneself, and identifies the twelve hour markings with the directions in which they point.

The nuclear grade describes how closely the nuclei of cancer cells look like the nuclei of normal breast cells. In general, the higher the nuclear grade, the more abnormal the nuclei are and the more aggressive the tumor cells tend to be. In breast cancer, nuclear grade is typically evaluated for ductal carcinoma in situ (DCIS) only.

Laboratory observations holding the interpretation of estrogen receptor status (e.g. positive, negative).

Value set containing In Situ Hybridization methods of determining HER2 status

Laboratory observations holding the interpretation of FISH HER2 receptor tests (e.g. positive, negative, equivocal)

Laboratory observations holding the interpretation of immunohistochemistry HER2 receptor tests (e.g. positive, negative, equivocal).

Value set containing possible scores resulting from determining HER2 status by immunohistochemistry. Based on LNC#LL4396-9 answer list.

An evaluation of the quantitative value from the Ki-67.

The method of lymph node sample collection for clinical LNI assessment.

The pathological finding for lymph node involvement.

Values expressing the degree of moveability of lymph node upon palpation.

The procedure method used to obtain the specimen analyzed for the pathological lymph node involvement.

The morphologic behavior of the cancer. These are equivalent to the suffix to the ICD-O-3 histologic type codes.

Interpretation of a test result as positive, negative, equivocal, or indeterminate.

Value set containing the values positive, negative and indeterminate. Equivalent to values in LOINC answer list LL2038-9/LL759-2

Value set containing the values positive and negative. VSAC value set OID 2.16.840.1.113762.1.4.1166.62.

Laboratory observations holding the interpretation of progesterone receptor status (e.g. positive, negative).

Interpretations of risk as high, intermediate, or low. Answer set taken from LOINC LL3198-0.

When staging was done, relative to treatment events (qualifier).

Staining intensity, to be reported as weak, moderate, or strong.

An evaluation of the lesion around the margins surrounding the tumor.