HL7 FHIR Implementation Guide: Breast Cancer Data, Release 1 - US Realm (Draft for Comment 2)

This page is part of the Breast Cancer Data Logical Models and FHIR Profiles (v0.2.0: STU 1 Draft) based on FHIR R3. . For a full list of available versions, see the Directory of published versions

DCISNuclearGradeVS


<ValueSet xmlns="http://hl7.org/fhir">
  <id value="oncology-DCISNuclearGradeVS"/>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
<p><b>BC DCISNuclearGradeVS ValueSet</b></p>
<p>The nuclear grade describes how closely the nuclei of cancer cells look like the nuclei of normal breast cells. In general, the higher the nuclear grade, the more abnormal the nuclei are and the more aggressive the tumor cells tend to be. In breast cancer, nuclear grade is typically evaluated for ductal carcinoma in situ (DCIS) only.</p>
</div>
  </text>
  <url
       value="http://hl7.org/fhir/us/breastcancer/ValueSet/oncology-DCISNuclearGradeVS"/>
  <identifier>
    <system value="http://hl7.org/fhir/us/breastcancer"/>
    <value value="oncology.DCISNuclearGradeVS"/>
  </identifier>
  <version value="0.2.0"/>
  <name value="DCISNuclearGradeVS"/>
  <title value="BC DCISNuclearGradeVS ValueSet"/>
  <status value="draft"/>
  <date value="2018-08-17T00:00:00+10:00"/>
  <publisher
             value="The HL7 Cancer Interoperability Group sponsored by Clinical Interoperability Council Work Group (CIC)"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="http://www.hl7.org/Special/committees/cic/index.cfm"/>
    </telecom>
  </contact>
  <description
               value="The nuclear grade describes how closely the nuclei of cancer cells look like the nuclei of normal breast cells. In general, the higher the nuclear grade, the more abnormal the nuclei are and the more aggressive the tumor cells tend to be. In breast cancer, nuclear grade is typically evaluated for ductal carcinoma in situ (DCIS) only."/>
  <compose>
    <include>
      <system value="http://snomed.info/sct"/>
      <concept>
        <code value="369781009"/>
        <display
                 value="Ductal carcinoma in situ nuclear pleomorphism, grade 1: monotonous nuclei, 1.5 - 2.0 red blood cells diameters, with finely dispersed chromatin and only occasional nucleoli (finding)"/>
      </concept>
      <concept>
        <code value="369782002"/>
        <display
                 value="Ductal carcinoma in situ nuclear pleomorphism, grade 2: neither nuclear grade 1 nor nuclear grade 3 (finding)"/>
      </concept>
      <concept>
        <code value="369783007"/>
        <display
                 value="Ductal carcinoma in situ nuclear pleomorphism, grade 3: Markedly pleomorphic nuclei, usually &gt;2.5 red blood cells diameters, with coarse chromatin and multiple nucleoli (finding)"/>
      </concept>
      <concept>
        <code value="384741006"/>
        <display value="Grade cannot be determined (finding)"/>
      </concept>
    </include>
  </compose>
</ValueSet>