This page is part of the Breast Cancer Data Logical Models and FHIR Profiles (v0.2.0: STU 1 Draft) based on FHIR R3. . For a full list of available versions, see the Directory of published versions
<StructureDefinition xmlns="http://hl7.org/fhir"> <id value="oncology-Ki-67NuclearAntigenValue-model"/> <text> <status value="generated"/> <div xmlns="http://www.w3.org/1999/xhtml"> <p><b>BC Ki-67NuclearAntigenValue Logical Model</b></p> <p>Ki-67 is a protein phosphatase whose expression is strongly associated with cell proliferation and encoded by the MKI67 gene. The Ki-67 antigen is measured quantitatively as a percentage.</p> </div> </text> <url value="http://hl7.org/fhir/us/breastcancer/StructureDefinition/oncology-Ki-67NuclearAntigenValue-model"/> <identifier> <system value="http://hl7.org/fhir/us/breastcancer"/> <value value="oncology.Ki-67NuclearAntigenValue"/> </identifier> <version value="0.2.0"/> <name value="Ki-67NuclearAntigenValueModel"/> <title value="BC Ki-67NuclearAntigenValue Logical Model"/> <status value="draft"/> <date value="2018-08-17T00:00:00+10:00"/> <publisher value="The HL7 Cancer Interoperability Group sponsored by Clinical Interoperability Council Work Group (CIC)"/> <contact> <telecom> <system value="url"/> <value value="http://www.hl7.org/Special/committees/cic/index.cfm"/> </telecom> </contact> <description value="Ki-67 is a protein phosphatase whose expression is strongly associated with cell proliferation and encoded by the MKI67 gene. The Ki-67 antigen is measured quantitatively as a percentage."/> <keyword> <system value="http://loinc.org"/> <code value="29593-1"/> <display value="Cells.Ki-67 nuclear Ag/100 cells in Tissue by Immune stain"/> </keyword> <kind value="logical"/> <abstract value="false"/> <type value="oncology-Ki-67NuclearAntigenValue-model"/> <baseDefinition value="http://hl7.org/fhir/StructureDefinition/Element"/> <derivation value="specialization"/> <snapshot> <element id="oncology-Ki-67NuclearAntigenValue-model"> <path value="oncology-Ki-67NuclearAntigenValue-model"/> <definition value="Ki-67 is a protein phosphatase whose expression is strongly associated with cell proliferation and encoded by the MKI67 gene. The Ki-67 antigen is measured quantitatively as a percentage."/> <min value="0"/> <max value="*"/> <base> <path value="oncology-Ki-67NuclearAntigenValue-model"/> <min value="0"/> <max value="*"/> </base> <mustSupport value="false"/> <isModifier value="false"/> <isSummary value="false"/> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.value"> <path value="oncology-Ki-67NuclearAntigenValue-model.value"/> <short value="Quantity representing ki-67 is a protein phosphatase whose expression is strongly associated with cell proliferation and encoded by the MKI67 gene. The Ki-67 antigen is measured quantitatively as a percentage."/> <definition value="Quantity representing ki-67 is a protein phosphatase whose expression is strongly associated with cell proliferation and encoded by the MKI67 gene. The Ki-67 antigen is measured quantitatively as a percentage."/> <min value="1"/> <max value="1"/> <base> <path value="oncology-Ki-67NuclearAntigenValue-model.value"/> <min value="1"/> <max value="1"/> </base> <type> <code value="http://hl7.org/fhir/us/breastcancer/StructureDefinition/shr-core-Quantity-model"/> </type> <mustSupport value="false"/> <isModifier value="false"/> <isSummary value="false"/> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.value.value"> <path value="oncology-Ki-67NuclearAntigenValue-model.value.value"/> <short value="Decimal representing a quantity with units, whose value may be bounded from above or below, as defined in FHIR"/> <definition value="Decimal representing a quantity with units, whose value may be bounded from above or below, as defined in FHIR"/> <min value="0"/> <max value="1"/> <base> <path value="oncology-Ki-67NuclearAntigenValue-model.value.value"/> <min value="0"/> <max value="1"/> </base> <type> <code value="decimal"/> </type> <mustSupport value="false"/> <isModifier value="false"/> <isSummary value="false"/> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.value.comparator"> <path value="oncology-Ki-67NuclearAntigenValue-model.value.comparator"/> <short value="Comparator"/> <definition value="Comparator"/> <min value="0"/> <max value="1"/> <base> <path value="oncology-Ki-67NuclearAntigenValue-model.value.comparator"/> <min value="0"/> <max value="1"/> </base> <type> <code value="code"/> </type> <mustSupport value="false"/> <isModifier value="false"/> <isSummary value="false"/> <binding> <strength value="required"/> <valueSetReference> <reference value="http://hl7.org/fhir/ValueSet/quantity-comparator"/> </valueSetReference> </binding> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.value.units"> <path value="oncology-Ki-67NuclearAntigenValue-model.value.units"/> <code> <system value="http://ncimeta.nci.nih.gov"/> <code value="C0805701"/> </code> <short value="Code for the unit of measure of the quantity."/> <definition value="Code for the unit of measure of the quantity."/> <min value="0"/> <max value="1"/> <base> <path value="oncology-Ki-67NuclearAntigenValue-model.value.units"/> <min value="0"/> <max value="1"/> </base> <type> <code value="Coding"/> </type> <mustSupport value="false"/> <isModifier value="false"/> <isSummary value="false"/> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.value.units.id"> <path value="oncology-Ki-67NuclearAntigenValue-model.value.units.id"/> <representation value="xmlAttr"/> <short value="xml:id (or equivalent in JSON)"/> <definition value="unique id for the element within a resource (for internal references). 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Note that a well-maintained code system does not need the version reported, because the meaning of codes is consistent across versions. 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There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely."/> <requirements value="This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing."/> <min value="0"/> <max value="1"/> <base> <path value="Coding.userSelected"/> <min value="0"/> <max value="1"/> </base> <type> <code value="boolean"/> </type> <isSummary value="true"/> <mapping> <identity value="v2"/> <map value="Sometimes implied by being first"/> </mapping> <mapping> <identity value="rim"/> <map value="CD.codingRationale"/> </mapping> <mapping> <identity value="orim"/> <map value="fhir:Coding.userSelected fhir:mapsTo dt:CDCoding.codingRationale. fhir:Coding.userSelected fhir:hasMap fhir:Coding.userSelected.map. fhir:Coding.userSelected.map a fhir:Map; fhir:target dt:CDCoding.codingRationale. fhir:Coding.userSelected\#true a [ fhir:source "true"; fhir:target dt:CDCoding.codingRationale\#O ]"/> </mapping> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.topicCode"> <path value="oncology-Ki-67NuclearAntigenValue-model.topicCode"/> <short value="The concept representing the finding or action that is the topic of the statement."/> <definition value="The concept representing the finding or action that is the topic of the statement. For action topics, the TopicCode represents the action being described. For findings, the TopicCode represents the 'question' or property being investigated. For evaluation result findings, the TopicCode contains a concept for an observable entity, such as systolic blood pressure. For assertion findings, the TopicCode contains a code representing the condition, allergy, or other item being asserted. 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There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely."/> <requirements value="This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing."/> <min value="0"/> <max value="1"/> <base> <path value="Coding.userSelected"/> <min value="0"/> <max value="1"/> </base> <type> <code value="boolean"/> </type> <isSummary value="true"/> <mapping> <identity value="v2"/> <map value="Sometimes implied by being first"/> </mapping> <mapping> <identity value="rim"/> <map value="CD.codingRationale"/> </mapping> <mapping> <identity value="orim"/> <map value="fhir:Coding.userSelected fhir:mapsTo dt:CDCoding.codingRationale. fhir:Coding.userSelected fhir:hasMap fhir:Coding.userSelected.map. fhir:Coding.userSelected.map a fhir:Map; fhir:target dt:CDCoding.codingRationale. fhir:Coding.userSelected\#true a [ fhir:source "true"; fhir:target dt:CDCoding.codingRationale\#O ]"/> </mapping> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.topicCode"> <path value="oncology-Ki-67NuclearAntigenValue-model.topicCode"/> <short value="The concept representing the finding or action that is the topic of the statement."/> <definition value="The concept representing the finding or action that is the topic of the statement. For action topics, the TopicCode represents the action being described. For findings, the TopicCode represents the 'question' or property being investigated. For evaluation result findings, the TopicCode contains a concept for an observable entity, such as systolic blood pressure. For assertion findings, the TopicCode contains a code representing the condition, allergy, or other item being asserted. In all cases, the TopicCode describes the topic independent of the context of the action or the finding."/> <min value="0"/> <max value="1"/> <base> <path value="oncology-Ki-67NuclearAntigenValue-model.topicCode"/> <min value="0"/> <max value="1"/> </base> <type> <code value="Coding"/> </type> <mustSupport value="false"/> <isModifier value="false"/> <isSummary value="false"/> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.exceptionValue"> <path value="oncology-Ki-67NuclearAntigenValue-model.exceptionValue"/> <short value="Reason that a value associated with a test or other finding is missing."/> <definition value="Reason that a value associated with a test or other finding is missing."/> <min value="0"/> <max value="1"/> <base> <path value="oncology-Ki-67NuclearAntigenValue-model.exceptionValue"/> <min value="0"/> <max value="1"/> </base> <type> <code value="Coding"/> </type> <mustSupport value="false"/> <isModifier value="false"/> <isSummary value="false"/> <binding> <strength value="extensible"/> <valueSetReference> <reference value="http://hl7.org/fhir/ValueSet/data-absent-reason"/> </valueSetReference> </binding> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.interpretation"> <path value="oncology-Ki-67NuclearAntigenValue-model.interpretation"/> <code> <system value="http://ncimeta.nci.nih.gov"/> <code value="C0420833"/> </code> <short value="A clinical interpretation of a finding (applies to both assertions and observation)."/> <definition value="A clinical interpretation of a finding (applies to both assertions and observation)."/> <min value="0"/> <max value="1"/> <base> <path value="oncology-Ki-67NuclearAntigenValue-model.interpretation"/> <min value="0"/> <max value="1"/> </base> <type> <code value="Coding"/> </type> <mustSupport value="false"/> <isModifier value="false"/> <isSummary value="false"/> <binding> <strength value="extensible"/> <valueSetReference> <reference value="http://hl7.org/fhir/ValueSet/observation-interpretation"/> </valueSetReference> </binding> </element> <element id="oncology-Ki-67NuclearAntigenValue-model.referenceRange"> <path value="oncology-Ki-67NuclearAntigenValue-model.referenceRange"/> <code> <system value="http://ncimeta.nci.nih.gov"/> <code value="C0883335"/> </code> <short value="The usual or acceptable range for a test result."/> <definition value="The usual or acceptable range for a test result."/> <min value="0"/> <max value="1"/> <base> <path value="oncology-Ki-67NuclearAntigenValue-model.referenceRange"/> <min value="0"/> <max value="1"/> </base> <type> <code value="http://hl7.org/fhir/us/breastcancer/StructureDefinition/cimi-topic-ReferenceRange-model"/> </type> <mustSupport value="false"/> <isModifier value="false"/> <isSummary value="false"/> </element> </differential> </StructureDefinition>