This page is part of the Breast Cancer Data Logical Models and FHIR Profiles (v0.2.0: STU 1 Draft) based on FHIR R3. . For a full list of available versions, see the Directory of published versions
The official URL for this logical model is:
http://hl7.org/fhir/us/breastcancer/StructureDefinition/oncology-Ki-67NuclearAntigen-model
Ki-67 is a protein phosphatase whose expression is strongly associated with cell proliferation and encoded by the MKI67 gene. The Ki67 labeling index is the fraction of Ki-67-positive cells to total cells in a tumor specimen and may be useful for determining prognosis with respect to survival and disease recurrence. The Ki-67 antigen is measured numerically as a percentage, and as an ordinal. The more positive cells there are, the more quickly they are dividing and forming new cells. ReferenceRange: Low <10, Intermediate 10-20, >20 High.
This logical model was published on Fri Aug 17 00:00:00 AEST 2018 as a draft by The HL7 Cancer Interoperability Group sponsored by Clinical Interoperability Council Work Group (CIC).
View the corresponding Ki-67NuclearAntigenProfile profile.
Name | Flags | Card. | Type | Description & Constraints |
---|---|---|---|---|
oncology-Ki-67NuclearAntigen-model | 0..* | |||
personOfRecord | 1..1 | Reference(BC PersonOfRecord Logical Model) | The person this entry belongs to. | |
laboratoryObservationTopic | 1..1 | BackboneElement | The topic composition for laboratory observations. A specimen is required, anatomical location is excluded (since the specimen indicates the collection body site). Also includes a diagnostic service (indicating the type of laboratory), not present in general observations. | |
topicCode | 1..1 | Coding | The concept representing the finding or action that is the topic of the statement. | |
extension | 0..* | Extension | Additional Content defined by implementations Slice: Unordered, Open by value:url | |
system | Σ | 1..1 | uri | Identity of the terminology system Fixed Value: http://loinc.org |
version | Σ | 0..1 | string | Version of the system - if relevant |
code | Σ | 1..1 | code | Symbol in syntax defined by the system Fixed Value: 33055-5 |
display | Σ | 0..1 | string | Representation defined by the system |
userSelected | Σ | 0..1 | boolean | If this coding was chosen directly by the user |
details | 0..1 | string | A text note containing additional details, explanation, description, comment, or summarization. Details can discuss, support, explain changes to, or dispute information. | |
category | 1..* | Coding | A class or division of people or things having particular shared characteristics | |
extension | 0..* | Extension | Additional Content defined by implementations Slice: Unordered, Open by value:url | |
system | Σ | 1..1 | uri | Identity of the terminology system Fixed Value: http://hl7.org/fhir/observation-category |
version | Σ | 0..1 | string | Version of the system - if relevant |
code | Σ | 1..1 | code | Symbol in syntax defined by the system Fixed Value: laboratory |
display | Σ | 0..1 | string | Representation defined by the system |
userSelected | Σ | 0..1 | boolean | If this coding was chosen directly by the user |
breastSpecimen | 1..1 | Reference(BC BreastSpecimen Logical Model) | Specimen resulting from biopsy or excision of breast and surrounding tissue. | |
evaluationComponent | 0..1 | A simplified, non-separable evaluation consisting of a finding code (represented by the Concept), value (or exception value), reference range, and interpretation. The subject of the evaluation component is the same as in the parent evaluation. | ||
ki-67NuclearAntigenValue | 0..1 | http://hl7.org/fhir/us/breastcancer/StructureDefinition/oncology-Ki-67NuclearAntigenValue-model | Ki-67 is a protein phosphatase whose expression is strongly associated with cell proliferation and encoded by the MKI67 gene. The Ki-67 antigen is measured quantitatively as a percentage. | |
diagnosticService | 0..* | Coding | The service completing the observations, e.g. biochemistry, microbiology, blood bank. | |
extension | 0..* | Extension | Additional Content defined by implementations Slice: Unordered, Open by value:url | |
system | Σ | 1..1 | uri | Identity of the terminology system Fixed Value: http://hl7.org/fhir/v2/0074 |
version | Σ | 0..1 | string | Version of the system - if relevant |
code | Σ | 1..1 | code | Symbol in syntax defined by the system Fixed Value: PAT |
display | Σ | 0..1 | string | Representation defined by the system |
userSelected | Σ | 0..1 | boolean | If this coding was chosen directly by the user |
observationContext | 1..1 | BackboneElement | Context for recording an evaluation result, used to indicate an evaluation has been made. | |
contextCode | 1..1 | Coding | A code representing the ontological status of the statement, e.g., whether it exists, does not exist, is planned, etc. | |
extension | 0..* | Extension | Additional Content defined by implementations Slice: Unordered, Open by value:url | |
system | Σ | 1..1 | uri | Identity of the terminology system Fixed Value: http://snomed.info/sct |
version | Σ | 0..1 | string | Version of the system - if relevant |
code | Σ | 1..1 | code | Symbol in syntax defined by the system Fixed Value: 424975005 |
display | Σ | 0..1 | string | Representation defined by the system |
userSelected | Σ | 0..1 | boolean | If this coding was chosen directly by the user |
encounter | 0..1 | http://hl7.org/fhir/us/breastcancer/StructureDefinition/cimi-encounter-Encounter-model | A description of an interaction between a patient and healthcare provider(s) for the purpose of providing healthcare service(s) or assessing the health status of a patient. | |
interpretation | 0..1 | Coding | A clinical interpretation of a finding (applies to both assertions and observation). Binding: Observation Interpretation Codes (extensible) | |
findingStatus | 1..1 | code | Indicates whether the finding is preliminary, amended, final, etc. Binding: ObservationStatus (required) | |
relevantTime | 0..1 | dateTime, http://hl7.org/fhir/us/breastcancer/StructureDefinition/shr-core-TimePeriod-model | The time or time period that the finding addresses. | |
resultValue | 0..1 | Coding | The finding itself, such as the blood pressure value recorded. Binding: BC Ki-67NuclearAntigenVS ValueSet (required) | |
deltaFlag | 0..1 | Coding | Indicator of significant change (delta) from the last or previous measurement. Binding: BC DeltaFlagVS ValueSet (required) | |
issued | 0..1 | instant | The date and time this observation was made available to providers, typically after the results have been reviewed and verified. | |
observer | 0..* | Reference(BC Practitioner Logical Model | BC Organization Logical Model | BC Patient Logical Model | BC RelatedPerson Logical Model) | The person or organization who observed or informed the reporter about the characteristic, potentially the clinician, the patient, or a related person. | |
Documentation for this format |
Downloads: StructureDefinition: (XML, JSON, TTL)
Path | Name | Conformance | ValueSet |
oncology-Ki-67NuclearAntigen-model.observationContext.interpretation | Observation Interpretation Codes | extensible | Observation Interpretation Codes |
oncology-Ki-67NuclearAntigen-model.observationContext.findingStatus | ObservationStatus | required | ObservationStatus |
oncology-Ki-67NuclearAntigen-model.observationContext.resultValue | BC Ki-67NuclearAntigenVS ValueSet | required | Ki-67NuclearAntigenVS |
oncology-Ki-67NuclearAntigen-model.observationContext.deltaFlag | BC DeltaFlagVS ValueSet | required | DeltaFlagVS |