This page is part of the FHIR Specification (v5.0.0: R5 - STU). This is the current published version in it's permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions 
. Page versions: R5 R4B
Example Evidence/example-stroke-alteplase-fatalICH (Turtle)
Raw Turtle (+ also see Turtle/RDF Format Specification)
Risk of fatal ICH with alteplase for stroke
@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
# - resource -------------------------------------------------------------------
[a fhir:Evidence ;
fhir:nodeRole fhir:treeRoot ;
fhir:id [ fhir:v "example-stroke-alteplase-fatalICH"] ; #
fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n \n <p>\n "Risk of fatal ICH with alteplase for stroke" is a univariate risk estimate.\n </p>\n \n </div>"
] ; #
fhir:url [ fhir:v "http://hl7.org/fhir/Evidence/example-stroke-alteplase-fatalICH"^^xsd:anyURI] ; #
fhir:identifier ( [
fhir:system [ fhir:v "urn:ietf:rfc:3986"^^xsd:anyURI ] ;
fhir:value [ fhir:v "urn:oid:2.16.840.1.113883.4.642.10.1" ]
] ) ; #
fhir:name [ fhir:v "RiskOfFatalICHWithAlteplaseForStroke"] ; #
fhir:title [ fhir:v "Risk of fatal ICH with alteplase for stroke"] ; #
fhir:status [ fhir:v "draft"] ; #
fhir:relatedArtifact ( [
fhir:type [ fhir:v "citation" ] ;
fhir:label [ fhir:v "Emberson 2014" ] ;
fhir:display [ fhir:v "Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials." ] ;
fhir:citation [ fhir:v "Emberson J, Lees KR, Lyden P, Blackwell L, Albers G, Bluhmki E, et al;Stroke Thrombolysis Trialists' Collaborative Group. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet 2014 Nov 29;384(9958):1929-35 PMID 25106063" ] ;
fhir:document [
fhir:url [ fhir:v "https://doi.org/10.1016/S0140-6736(14)60584-5"^^xsd:anyURI ]
]
] ) ; #
fhir:description [ fhir:v "2.7% incidence of fatal intracranial hemorrhage within 7 days with alteplase in patients with acute ischemic stroke"] ; #
fhir:variableDefinition ( [
fhir:variableRole [
fhir:coding ( [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/variable-role"^^xsd:anyURI ] ;
fhir:code [ fhir:v "population" ] ;
fhir:display [ fhir:v "population" ]
] )
] ;
fhir:observed [
fhir:reference [ fhir:v "Group/AcuteIschemicStroke" ] ;
fhir:type [ fhir:v "Group"^^xsd:anyURI ] ;
fhir:display [ fhir:v "adults with acute ischemic stroke" ]
] ;
fhir:intended [
fhir:reference [ fhir:v "Group/AcuteIschemicStroke" ] ;
fhir:type [ fhir:v "Group"^^xsd:anyURI ] ;
fhir:display [ fhir:v "adults with acute ischemic stroke" ]
]
] [
fhir:variableRole [
fhir:coding ( [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/variable-role"^^xsd:anyURI ] ;
fhir:code [ fhir:v "population" ] ;
fhir:display [ fhir:v "population" ]
] )
] ;
fhir:observed [
fhir:reference [ fhir:v "Group/Emberson-2014-IPD-MA-Alteplase-Cohort" ] ;
fhir:type [ fhir:v "Group"^^xsd:anyURI ] ;
fhir:display [ fhir:v "Emberson 2014 IPD-MA Alteplase Cohort" ]
] ;
fhir:intended [
fhir:reference [ fhir:v "Group/AcuteIschemicStrokeTreatedWithAlteplase" ] ;
fhir:type [ fhir:v "Group"^^xsd:anyURI ] ;
fhir:display [ fhir:v "adults with acute ischemic stroke treated with alteplase" ]
]
] [
fhir:variableRole [
fhir:coding ( [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/variable-role"^^xsd:anyURI ] ;
fhir:code [ fhir:v "measuredVariable" ] ;
fhir:display [ fhir:v "measured variable" ]
] )
] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/example-fatal-ICH-in-7-days" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "fatal ICH" ]
] ;
fhir:intended [
fhir:reference [ fhir:v "EvidenceVariable/example-fatal-ICH-in-7-days" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "fatal ICH" ]
]
] ) ; #
fhir:synthesisType [
fhir:coding ( [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/synthesis-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "IPD-MA" ] ;
fhir:display [ fhir:v "individual patient data meta-analysis" ]
] )
] ; #
fhir:studyDesign ( [
fhir:coding ( [
fhir:system [ fhir:v "http://hl7.org/fhir/study-design"^^xsd:anyURI ] ;
fhir:code [ fhir:v "SEVCO:01003" ] ;
fhir:display [ fhir:v "randomized assignment" ]
] )
] ) ; #
fhir:statistic ( [
fhir:statisticType [
fhir:coding ( [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/statistic-type"^^xsd:anyURI ] ;
fhir:code [ fhir:v "C44256" ] ;
fhir:display [ fhir:v "Proportion" ]
] )
] ;
fhir:quantity [
fhir:value [ fhir:v "0.026835741669"^^xsd:decimal ]
] ;
fhir:numberOfEvents [ fhir:v "91"^^xsd:nonNegativeInteger ] ;
fhir:sampleSize [
fhir:numberOfStudies [ fhir:v "9"^^xsd:nonNegativeInteger ] ;
fhir:numberOfParticipants [ fhir:v "3391"^^xsd:nonNegativeInteger ]
]
] )] . #
# -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the
examples are correct and useful, but they are not a normative part
of the specification.
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