Release 4

This page is part of the FHIR Specification (v4.0.1: R4 - Mixed Normative and STU) in it's permanent home (it will always be available at this URL). The current version which supercedes this version is 5.0.0. For a full list of available versions, see the Directory of published versions

11.15 Resource MedicinalProductInteraction - Content

Biomedical Research and Regulation

Work Group

Maturity Level: 0

Trial Use

Security Category: Anonymous

Compartments: Not linked to any defined compartments

The interactions of the medicinal product with other medicinal products, or other forms of interactions.

11.15.1 Scope and Usage

For detailing potential interactions associated with usage of a medicinal product

Structure

Name	Flags	Card.	Type	Description & Constraints
MedicinalProductInteraction	Σ TU		DomainResource	MedicinalProductInteraction Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension
subject	Σ	0..*	Reference(MedicinalProduct \| Medication \| Substance)	The medication for which this is a described interaction
description	Σ	0..1	string	The interaction described
interactant	Σ	0..*	BackboneElement	The specific medication, food or laboratory test that interacts
item[x]	Σ	1..1		The specific medication, food or laboratory test that interacts
itemReference			Reference(MedicinalProduct \| Medication \| Substance \| ObservationDefinition)
itemCodeableConcept			CodeableConcept
type	Σ	0..1	CodeableConcept	The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction
effect	Σ	0..1	CodeableConcept	The effect of the interaction, for example "reduced gastric absorption of primary medication"
incidence	Σ	0..1	CodeableConcept	The incidence of the interaction, e.g. theoretical, observed
management	Σ	0..1	CodeableConcept	Actions for managing the interaction
Documentation for this format

UML Diagram (Legend)

XML Template

<MedicinalProductInteraction xmlns="http://hl7.org/fhir"> 
 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <subject><!-- 0..* Reference(MedicinalProduct|Medication|Substance) The medication for which this is a described interaction --></subject>
 <description value="[string]"/><!-- 0..1 The interaction described -->
 <interactant>  <!-- 0..* The specific medication, food or laboratory test that interacts -->
  <item[x]><!-- 1..1 Reference(MedicinalProduct|Medication|Substance|
    ObservationDefinition)|CodeableConcept The specific medication, food or laboratory test that interacts --></item[x]>
 </interactant>
 <type><!-- 0..1 CodeableConcept The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction --></type>
 <effect><!-- 0..1 CodeableConcept The effect of the interaction, for example "reduced gastric absorption of primary medication" --></effect>
 <incidence><!-- 0..1 CodeableConcept The incidence of the interaction, e.g. theoretical, observed --></incidence>
 <management><!-- 0..1 CodeableConcept Actions for managing the interaction --></management>
</MedicinalProductInteraction>

JSON Template

{
  "resourceType" : "MedicinalProductInteraction",
  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "subject" : [{ Reference(MedicinalProduct|Medication|Substance) }], // The medication for which this is a described interaction
  "description" : "<string>", // The interaction described
  "interactant" : [{ // The specific medication, food or laboratory test that interacts
    // item[x]: The specific medication, food or laboratory test that interacts. One of these 2:
    "itemReference" : { Reference(MedicinalProduct|Medication|Substance|
    ObservationDefinition) }
    "itemCodeableConcept" : { CodeableConcept }
  }],
  "type" : { CodeableConcept }, // The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction
  "effect" : { CodeableConcept }, // The effect of the interaction, for example "reduced gastric absorption of primary medication"
  "incidence" : { CodeableConcept }, // The incidence of the interaction, e.g. theoretical, observed
  "management" : { CodeableConcept } // Actions for managing the interaction
}

Turtle Template

@prefix fhir: <http://hl7.org/fhir/> .


[ a fhir:MedicinalProductInteraction;
  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:MedicinalProductInteraction.subject [ Reference(MedicinalProduct|Medication|Substance) ], ... ; # 0..* The medication for which this is a described interaction
  fhir:MedicinalProductInteraction.description [ string ]; # 0..1 The interaction described
  fhir:MedicinalProductInteraction.interactant [ # 0..* The specific medication, food or laboratory test that interacts
    # MedicinalProductInteraction.interactant.item[x] : 1..1 The specific medication, food or laboratory test that interacts. One of these 2
      fhir:MedicinalProductInteraction.interactant.itemReference [ Reference(MedicinalProduct|Medication|Substance|ObservationDefinition) ]
      fhir:MedicinalProductInteraction.interactant.itemCodeableConcept [ CodeableConcept ]
  ], ...;
  fhir:MedicinalProductInteraction.type [ CodeableConcept ]; # 0..1 The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction
  fhir:MedicinalProductInteraction.effect [ CodeableConcept ]; # 0..1 The effect of the interaction, for example "reduced gastric absorption of primary medication"
  fhir:MedicinalProductInteraction.incidence [ CodeableConcept ]; # 0..1 The incidence of the interaction, e.g. theoretical, observed
  fhir:MedicinalProductInteraction.management [ CodeableConcept ]; # 0..1 Actions for managing the interaction
]

Changes since R3

This resource did not exist in Release 2

This analysis is available as XML or JSON.

Structure

Name	Flags	Card.	Type	Description & Constraints
MedicinalProductInteraction	Σ TU		DomainResource	MedicinalProductInteraction Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension
subject	Σ	0..*	Reference(MedicinalProduct \| Medication \| Substance)	The medication for which this is a described interaction
description	Σ	0..1	string	The interaction described
interactant	Σ	0..*	BackboneElement	The specific medication, food or laboratory test that interacts
item[x]	Σ	1..1		The specific medication, food or laboratory test that interacts
itemReference			Reference(MedicinalProduct \| Medication \| Substance \| ObservationDefinition)
itemCodeableConcept			CodeableConcept
type	Σ	0..1	CodeableConcept	The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction
effect	Σ	0..1	CodeableConcept	The effect of the interaction, for example "reduced gastric absorption of primary medication"
incidence	Σ	0..1	CodeableConcept	The incidence of the interaction, e.g. theoretical, observed
management	Σ	0..1	CodeableConcept	Actions for managing the interaction
Documentation for this format

UML Diagram (Legend)

XML Template

<MedicinalProductInteraction xmlns="http://hl7.org/fhir"> 
 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <subject><!-- 0..* Reference(MedicinalProduct|Medication|Substance) The medication for which this is a described interaction --></subject>
 <description value="[string]"/><!-- 0..1 The interaction described -->
 <interactant>  <!-- 0..* The specific medication, food or laboratory test that interacts -->
  <item[x]><!-- 1..1 Reference(MedicinalProduct|Medication|Substance|
    ObservationDefinition)|CodeableConcept The specific medication, food or laboratory test that interacts --></item[x]>
 </interactant>
 <type><!-- 0..1 CodeableConcept The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction --></type>
 <effect><!-- 0..1 CodeableConcept The effect of the interaction, for example "reduced gastric absorption of primary medication" --></effect>
 <incidence><!-- 0..1 CodeableConcept The incidence of the interaction, e.g. theoretical, observed --></incidence>
 <management><!-- 0..1 CodeableConcept Actions for managing the interaction --></management>
</MedicinalProductInteraction>

JSON Template

{
  "resourceType" : "MedicinalProductInteraction",
  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "subject" : [{ Reference(MedicinalProduct|Medication|Substance) }], // The medication for which this is a described interaction
  "description" : "<string>", // The interaction described
  "interactant" : [{ // The specific medication, food or laboratory test that interacts
    // item[x]: The specific medication, food or laboratory test that interacts. One of these 2:
    "itemReference" : { Reference(MedicinalProduct|Medication|Substance|
    ObservationDefinition) }
    "itemCodeableConcept" : { CodeableConcept }
  }],
  "type" : { CodeableConcept }, // The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction
  "effect" : { CodeableConcept }, // The effect of the interaction, for example "reduced gastric absorption of primary medication"
  "incidence" : { CodeableConcept }, // The incidence of the interaction, e.g. theoretical, observed
  "management" : { CodeableConcept } // Actions for managing the interaction
}

Turtle Template

@prefix fhir: <http://hl7.org/fhir/> .


[ a fhir:MedicinalProductInteraction;
  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:MedicinalProductInteraction.subject [ Reference(MedicinalProduct|Medication|Substance) ], ... ; # 0..* The medication for which this is a described interaction
  fhir:MedicinalProductInteraction.description [ string ]; # 0..1 The interaction described
  fhir:MedicinalProductInteraction.interactant [ # 0..* The specific medication, food or laboratory test that interacts
    # MedicinalProductInteraction.interactant.item[x] : 1..1 The specific medication, food or laboratory test that interacts. One of these 2
      fhir:MedicinalProductInteraction.interactant.itemReference [ Reference(MedicinalProduct|Medication|Substance|ObservationDefinition) ]
      fhir:MedicinalProductInteraction.interactant.itemCodeableConcept [ CodeableConcept ]
  ], ...;
  fhir:MedicinalProductInteraction.type [ CodeableConcept ]; # 0..1 The type of the interaction e.g. drug-drug interaction, drug-food interaction, drug-lab test interaction
  fhir:MedicinalProductInteraction.effect [ CodeableConcept ]; # 0..1 The effect of the interaction, for example "reduced gastric absorption of primary medication"
  fhir:MedicinalProductInteraction.incidence [ CodeableConcept ]; # 0..1 The incidence of the interaction, e.g. theoretical, observed
  fhir:MedicinalProductInteraction.management [ CodeableConcept ]; # 0..1 Actions for managing the interaction
]

Changes since Release 3

This resource did not exist in Release 2

This analysis is available as XML or JSON.

See the Profiles & Extensions and the alternate definitions: Master Definition XML + JSON, XML Schema/Schematron + JSON Schema, ShEx (for Turtle) + see the extensions & the dependency analysis

11.15.3 Search Parameters

Search parameters for this resource. The common parameters also apply. See Searching for more information about searching in REST, messaging, and services.

Name	Type	Description	Expression	In Common
subject	reference	The medication for which this is an interaction	MedicinalProductInteraction.subject (Medication, Substance, MedicinalProduct)