This value set has an inline code system http://hl7.org/fhir/v3/substanceAdminSubstitution, which defines the following codes:
Lvl | Code | Display | Definition |
1 | _ActSubstanceAdminSubstitutionCode | ActSubstanceAdminSubstitutionCode | Description: Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects. |
2 | E | equivalent | Description: Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product. |
3 | EC | equivalent composition | Description:
Substitution occurred or is permitted with another product that is a:
pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester
pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration
Examples:
Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate
Pharmaceutical equivalent: Lisonpril for Zestril |
4 | BC | brand composition | Description:
Substitution occurred or is permitted between equivalent Brands but not Generics
Examples:
Zestril for Prinivil
Coumadin for Jantoven |
4 | G | generic composition | Description: Substitution occurred or is permitted between equivalent Generics but not Brands
Examples:
Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp) |
3 | TE | therapeutic alternative | Description: Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.
Examples:
ranitidine for Tagamet |
4 | TB | therapeutic brand | Description: Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics >
Examples:
Zantac for Tagamet |
4 | TG | therapeutic generic | Description: Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands >
Examples:
Ranitidine for cimetidine |
2 | F | formulary | Description: This substitution was performed or is permitted based on formulary guidelines. |
2 | N | none | No substitution occurred or is permitted. |