This page is part of the FHIR Specification (v3.5.0: R4 Ballot #2). The current version which supercedes this version is 5.0.0. For a full list of available versions, see the Directory of published versions
Biomedical Research and Regulation Work Group | Maturity Level: 0 | Trial Use | Compartments: Not linked to any defined compartments |
The clinical particulars - indications, contraindications etc. of a medicinal product, including for regulatory purposes.
A set of clinically relevent aspects relating to the potential uses and problems associated with a medicinal product
Structure
Name | Flags | Card. | Type | Description & Constraints |
---|---|---|---|---|
MedicinalProductClinicals | ΣTU | DomainResource | MedicinalProductClinicals Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension | |
undesirableEffects | Σ | 0..* | BackboneElement | Describe the undesirable effects of the medicinal product |
symptomConditionEffect | Σ | 0..1 | CodeableConcept | The symptom, condition or undesirable effect |
classification | Σ | 0..1 | CodeableConcept | Classification of the effect |
frequencyOfOccurrence | Σ | 0..1 | CodeableConcept | The frequency of occurrence of the effect |
population | Σ | 0..* | BackboneElement | The population group to which this applies |
age[x] | Σ | 0..1 | The age of the specific population | |
ageRange | Range | |||
ageCodeableConcept | CodeableConcept | |||
gender | Σ | 0..1 | CodeableConcept | The gender of the specific population |
race | Σ | 0..1 | CodeableConcept | Race of the specific population |
physiologicalCondition | Σ | 0..1 | CodeableConcept | The existing physiological conditions of the specific population to which this applies |
therapeuticIndication | Σ | 1..* | BackboneElement | Indication for the Medicinal Product |
diseaseSymptomProcedure | Σ | 0..1 | CodeableConcept | The disease, symptom or procedure that is the indication for treatment |
diseaseStatus | Σ | 0..1 | CodeableConcept | The status of the disease or symptom for which the indication applies |
comorbidity | Σ | 0..* | CodeableConcept | Comorbidity (concurrent condition) or co-infection as part of the indication |
intendedEffect | Σ | 0..1 | CodeableConcept | The intended effect, aim or strategy to be achieved by the indication |
duration | Σ | 0..1 | Quantity | Timing or duration information as part of the indication |
undesirableEffects | Σ | 0..* | see undesirableEffects | Information about the use of the medicinal product in relation to other therapies as part of the indication |
otherTherapy | Σ | 0..* | BackboneElement | Information about the use of the medicinal product in relation to other therapies described as part of the indication |
therapyRelationshipType | Σ | 1..1 | CodeableConcept | The type of relationship between the medicinal product indication or contraindication and another therapy |
medication[x] | Σ | 1..1 | Reference to a specific medication (active substance, medicinal product or class of products) as part of an indication or contraindication | |
medicationCodeableConcept | CodeableConcept | |||
medicationReference | Reference(MedicinalProduct | Medication | Substance | SubstanceSpecification) | |||
population | Σ | 0..* | see population | The population group to which this applies |
contraindication | Σ | 0..* | BackboneElement | Contraindication for the medicinal product |
disease | Σ | 0..1 | CodeableConcept | The disease, symptom or procedure for the contraindication |
diseaseStatus | Σ | 0..1 | CodeableConcept | The status of the disease or symptom for the contraindication |
comorbidity | Σ | 0..* | CodeableConcept | A comorbidity (concurrent condition) or coinfection |
therapeuticIndication | Σ | 0..* | see therapeuticIndication | Information about the use of the medicinal product in relation to other therapies as part of the indication |
otherTherapy | Σ | 0..* | see otherTherapy | Information about the use of the medicinal product in relation to other therapies described as part of the contraindication |
population | Σ | 0..* | see population | The population group to which this applies |
interactions | Σ | 0..* | BackboneElement | The interactions of the medicinal product with other medicinal products, or other forms of interactions |
interaction | Σ | 0..1 | string | The interaction described |
interactant | Σ | 0..* | CodeableConcept | The specific medication, food or laboratory test that interacts |
type | Σ | 0..1 | CodeableConcept | The type of the interaction |
effect | Σ | 0..1 | CodeableConcept | The effect of the interaction |
incidence | Σ | 0..1 | CodeableConcept | The incidence of the interaction |
management | Σ | 0..1 | CodeableConcept | Actions for managing the interaction |
Documentation for this format |
UML Diagram (Legend)
XML Template
<MedicinalProductClinicals xmlns="http://hl7.org/fhir"> <!-- from Resource: id, meta, implicitRules, and language --> <!-- from DomainResource: text, contained, extension, and modifierExtension --> <undesirableEffects> <!-- 0..* Describe the undesirable effects of the medicinal product --> <symptomConditionEffect><!-- 0..1 CodeableConcept The symptom, condition or undesirable effect --></symptomConditionEffect> <classification><!-- 0..1 CodeableConcept Classification of the effect --></classification> <frequencyOfOccurrence><!-- 0..1 CodeableConcept The frequency of occurrence of the effect --></frequencyOfOccurrence> <population> <!-- 0..* The population group to which this applies --> <age[x]><!-- 0..1 Range|CodeableConcept The age of the specific population --></age[x]> <gender><!-- 0..1 CodeableConcept The gender of the specific population --></gender> <race><!-- 0..1 CodeableConcept Race of the specific population --></race> <physiologicalCondition><!-- 0..1 CodeableConcept The existing physiological conditions of the specific population to which this applies --></physiologicalCondition> </population> </undesirableEffects> <therapeuticIndication> <!-- 1..* Indication for the Medicinal Product --> <diseaseSymptomProcedure><!-- 0..1 CodeableConcept The disease, symptom or procedure that is the indication for treatment --></diseaseSymptomProcedure> <diseaseStatus><!-- 0..1 CodeableConcept The status of the disease or symptom for which the indication applies --></diseaseStatus> <comorbidity><!-- 0..* CodeableConcept Comorbidity (concurrent condition) or co-infection as part of the indication --></comorbidity> <intendedEffect><!-- 0..1 CodeableConcept The intended effect, aim or strategy to be achieved by the indication --></intendedEffect> <duration><!-- 0..1 Quantity Timing or duration information as part of the indication --></duration> <undesirableEffects><!-- 0..* Content as for MedicinalProductClinicals.undesirableEffects Information about the use of the medicinal product in relation to other therapies as part of the indication --></undesirableEffects> <otherTherapy> <!-- 0..* Information about the use of the medicinal product in relation to other therapies described as part of the indication --> <therapyRelationshipType><!-- 1..1 CodeableConcept The type of relationship between the medicinal product indication or contraindication and another therapy --></therapyRelationshipType> <medication[x]><!-- 1..1 CodeableConcept|Reference(MedicinalProduct|Medication| Substance|SubstanceSpecification) Reference to a specific medication (active substance, medicinal product or class of products) as part of an indication or contraindication --></medication[x]> </otherTherapy> <population><!-- 0..* Content as for MedicinalProductClinicals.undesirableEffects.population The population group to which this applies --></population> </therapeuticIndication> <contraindication> <!-- 0..* Contraindication for the medicinal product --> <disease><!-- 0..1 CodeableConcept The disease, symptom or procedure for the contraindication --></disease> <diseaseStatus><!-- 0..1 CodeableConcept The status of the disease or symptom for the contraindication --></diseaseStatus> <comorbidity><!-- 0..* CodeableConcept A comorbidity (concurrent condition) or coinfection --></comorbidity> <therapeuticIndication><!-- 0..* Content as for MedicinalProductClinicals.therapeuticIndication Information about the use of the medicinal product in relation to other therapies as part of the indication --></therapeuticIndication> <otherTherapy><!-- 0..* Content as for MedicinalProductClinicals.therapeuticIndication.otherTherapy Information about the use of the medicinal product in relation to other therapies described as part of the contraindication --></otherTherapy> <population><!-- 0..* Content as for MedicinalProductClinicals.undesirableEffects.population The population group to which this applies --></population> </contraindication> <interactions> <!-- 0..* The interactions of the medicinal product with other medicinal products, or other forms of interactions --> <interaction value="[string]"/><!-- 0..1 The interaction described --> <interactant><!-- 0..* CodeableConcept The specific medication, food or laboratory test that interacts --></interactant> <type><!-- 0..1 CodeableConcept The type of the interaction --></type> <effect><!-- 0..1 CodeableConcept The effect of the interaction --></effect> <incidence><!-- 0..1 CodeableConcept The incidence of the interaction --></incidence> <management><!-- 0..1 CodeableConcept Actions for managing the interaction --></management> </interactions> </MedicinalProductClinicals>
JSON Template
{ "resourceType" : "MedicinalProductClinicals", // from Resource: id, meta, implicitRules, and language // from DomainResource: text, contained, extension, and modifierExtension "undesirableEffects" : [{ // Describe the undesirable effects of the medicinal product "symptomConditionEffect" : { CodeableConcept }, // The symptom, condition or undesirable effect "classification" : { CodeableConcept }, // Classification of the effect "frequencyOfOccurrence" : { CodeableConcept }, // The frequency of occurrence of the effect "population" : [{ // The population group to which this applies // age[x]: The age of the specific population. One of these 2: "ageRange" : { Range }, "ageCodeableConcept" : { CodeableConcept }, "gender" : { CodeableConcept }, // The gender of the specific population "race" : { CodeableConcept }, // Race of the specific population "physiologicalCondition" : { CodeableConcept } // The existing physiological conditions of the specific population to which this applies }] }], "therapeuticIndication" : [{ // R! Indication for the Medicinal Product "diseaseSymptomProcedure" : { CodeableConcept }, // The disease, symptom or procedure that is the indication for treatment "diseaseStatus" : { CodeableConcept }, // The status of the disease or symptom for which the indication applies "comorbidity" : [{ CodeableConcept }], // Comorbidity (concurrent condition) or co-infection as part of the indication "intendedEffect" : { CodeableConcept }, // The intended effect, aim or strategy to be achieved by the indication "duration" : { Quantity }, // Timing or duration information as part of the indication "undesirableEffects" : [{ Content as for MedicinalProductClinicals.undesirableEffects }], // Information about the use of the medicinal product in relation to other therapies as part of the indication "otherTherapy" : [{ // Information about the use of the medicinal product in relation to other therapies described as part of the indication "therapyRelationshipType" : { CodeableConcept }, // R! The type of relationship between the medicinal product indication or contraindication and another therapy // medication[x]: Reference to a specific medication (active substance, medicinal product or class of products) as part of an indication or contraindication. One of these 2: "medicationCodeableConcept" : { CodeableConcept } "medicationReference" : { Reference(MedicinalProduct|Medication|Substance| SubstanceSpecification) } }], "population" : [{ Content as for MedicinalProductClinicals.undesirableEffects.population }] // The population group to which this applies }], "contraindication" : [{ // Contraindication for the medicinal product "disease" : { CodeableConcept }, // The disease, symptom or procedure for the contraindication "diseaseStatus" : { CodeableConcept }, // The status of the disease or symptom for the contraindication "comorbidity" : [{ CodeableConcept }], // A comorbidity (concurrent condition) or coinfection "therapeuticIndication" : [{ Content as for MedicinalProductClinicals.therapeuticIndication }], // Information about the use of the medicinal product in relation to other therapies as part of the indication "otherTherapy" : [{ Content as for MedicinalProductClinicals.therapeuticIndication.otherTherapy }], // Information about the use of the medicinal product in relation to other therapies described as part of the contraindication "population" : [{ Content as for MedicinalProductClinicals.undesirableEffects.population }] // The population group to which this applies }], "interactions" : [{ // The interactions of the medicinal product with other medicinal products, or other forms of interactions "interaction" : "<string>", // The interaction described "interactant" : [{ CodeableConcept }], // The specific medication, food or laboratory test that interacts "type" : { CodeableConcept }, // The type of the interaction "effect" : { CodeableConcept }, // The effect of the interaction "incidence" : { CodeableConcept }, // The incidence of the interaction "management" : { CodeableConcept } // Actions for managing the interaction }] }
Turtle Template
@prefix fhir: <http://hl7.org/fhir/> . [ a fhir:MedicinalProductClinicals; fhir:nodeRole fhir:treeRoot; # if this is the parser root # from Resource: .id, .meta, .implicitRules, and .language # from DomainResource: .text, .contained, .extension, and .modifierExtension fhir:MedicinalProductClinicals.undesirableEffects [ # 0..* Describe the undesirable effects of the medicinal product fhir:MedicinalProductClinicals.undesirableEffects.symptomConditionEffect [ CodeableConcept ]; # 0..1 The symptom, condition or undesirable effect fhir:MedicinalProductClinicals.undesirableEffects.classification [ CodeableConcept ]; # 0..1 Classification of the effect fhir:MedicinalProductClinicals.undesirableEffects.frequencyOfOccurrence [ CodeableConcept ]; # 0..1 The frequency of occurrence of the effect fhir:MedicinalProductClinicals.undesirableEffects.population [ # 0..* The population group to which this applies # MedicinalProductClinicals.undesirableEffects.population.age[x] : 0..1 The age of the specific population. One of these 2 fhir:MedicinalProductClinicals.undesirableEffects.population.ageRange [ Range ] fhir:MedicinalProductClinicals.undesirableEffects.population.ageCodeableConcept [ CodeableConcept ] fhir:MedicinalProductClinicals.undesirableEffects.population.gender [ CodeableConcept ]; # 0..1 The gender of the specific population fhir:MedicinalProductClinicals.undesirableEffects.population.race [ CodeableConcept ]; # 0..1 Race of the specific population fhir:MedicinalProductClinicals.undesirableEffects.population.physiologicalCondition [ CodeableConcept ]; # 0..1 The existing physiological conditions of the specific population to which this applies ], ...; ], ...; fhir:MedicinalProductClinicals.therapeuticIndication [ # 1..* Indication for the Medicinal Product fhir:MedicinalProductClinicals.therapeuticIndication.diseaseSymptomProcedure [ CodeableConcept ]; # 0..1 The disease, symptom or procedure that is the indication for treatment fhir:MedicinalProductClinicals.therapeuticIndication.diseaseStatus [ CodeableConcept ]; # 0..1 The status of the disease or symptom for which the indication applies fhir:MedicinalProductClinicals.therapeuticIndication.comorbidity [ CodeableConcept ], ... ; # 0..* Comorbidity (concurrent condition) or co-infection as part of the indication fhir:MedicinalProductClinicals.therapeuticIndication.intendedEffect [ CodeableConcept ]; # 0..1 The intended effect, aim or strategy to be achieved by the indication fhir:MedicinalProductClinicals.therapeuticIndication.duration [ Quantity ]; # 0..1 Timing or duration information as part of the indication fhir:MedicinalProductClinicals.therapeuticIndication.undesirableEffects [ See MedicinalProductClinicals.undesirableEffects ], ... ; # 0..* Information about the use of the medicinal product in relation to other therapies as part of the indication fhir:MedicinalProductClinicals.therapeuticIndication.otherTherapy [ # 0..* Information about the use of the medicinal product in relation to other therapies described as part of the indication fhir:MedicinalProductClinicals.therapeuticIndication.otherTherapy.therapyRelationshipType [ CodeableConcept ]; # 1..1 The type of relationship between the medicinal product indication or contraindication and another therapy # MedicinalProductClinicals.therapeuticIndication.otherTherapy.medication[x] : 1..1 Reference to a specific medication (active substance, medicinal product or class of products) as part of an indication or contraindication. One of these 2 fhir:MedicinalProductClinicals.therapeuticIndication.otherTherapy.medicationCodeableConcept [ CodeableConcept ] fhir:MedicinalProductClinicals.therapeuticIndication.otherTherapy.medicationReference [ Reference(MedicinalProduct|Medication|Substance|SubstanceSpecification) ] ], ...; fhir:MedicinalProductClinicals.therapeuticIndication.population [ See MedicinalProductClinicals.undesirableEffects.population ], ... ; # 0..* The population group to which this applies ], ...; fhir:MedicinalProductClinicals.contraindication [ # 0..* Contraindication for the medicinal product fhir:MedicinalProductClinicals.contraindication.disease [ CodeableConcept ]; # 0..1 The disease, symptom or procedure for the contraindication fhir:MedicinalProductClinicals.contraindication.diseaseStatus [ CodeableConcept ]; # 0..1 The status of the disease or symptom for the contraindication fhir:MedicinalProductClinicals.contraindication.comorbidity [ CodeableConcept ], ... ; # 0..* A comorbidity (concurrent condition) or coinfection fhir:MedicinalProductClinicals.contraindication.therapeuticIndication [ See MedicinalProductClinicals.therapeuticIndication ], ... ; # 0..* Information about the use of the medicinal product in relation to other therapies as part of the indication fhir:MedicinalProductClinicals.contraindication.otherTherapy [ See MedicinalProductClinicals.therapeuticIndication.otherTherapy ], ... ; # 0..* Information about the use of the medicinal product in relation to other therapies described as part of the contraindication fhir:MedicinalProductClinicals.contraindication.population [ See MedicinalProductClinicals.undesirableEffects.population ], ... ; # 0..* The population group to which this applies ], ...; fhir:MedicinalProductClinicals.interactions [ # 0..* The interactions of the medicinal product with other medicinal products, or other forms of interactions fhir:MedicinalProductClinicals.interactions.interaction [ string ]; # 0..1 The interaction described fhir:MedicinalProductClinicals.interactions.interactant [ CodeableConcept ], ... ; # 0..* The specific medication, food or laboratory test that interacts fhir:MedicinalProductClinicals.interactions.type [ CodeableConcept ]; # 0..1 The type of the interaction fhir:MedicinalProductClinicals.interactions.effect [ CodeableConcept ]; # 0..1 The effect of the interaction fhir:MedicinalProductClinicals.interactions.incidence [ CodeableConcept ]; # 0..1 The incidence of the interaction fhir:MedicinalProductClinicals.interactions.management [ CodeableConcept ]; # 0..1 Actions for managing the interaction ], ...; ]
Changes since R3
This resource did not exist in Release 2
This analysis is available as XML or JSON.
See R3 <--> R4 Conversion Maps (status = Not Mapped)
Structure
Name | Flags | Card. | Type | Description & Constraints |
---|---|---|---|---|
MedicinalProductClinicals | ΣTU | DomainResource | MedicinalProductClinicals Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension | |
undesirableEffects | Σ | 0..* | BackboneElement | Describe the undesirable effects of the medicinal product |
symptomConditionEffect | Σ | 0..1 | CodeableConcept | The symptom, condition or undesirable effect |
classification | Σ | 0..1 | CodeableConcept | Classification of the effect |
frequencyOfOccurrence | Σ | 0..1 | CodeableConcept | The frequency of occurrence of the effect |
population | Σ | 0..* | BackboneElement | The population group to which this applies |
age[x] | Σ | 0..1 | The age of the specific population | |
ageRange | Range | |||
ageCodeableConcept | CodeableConcept | |||
gender | Σ | 0..1 | CodeableConcept | The gender of the specific population |
race | Σ | 0..1 | CodeableConcept | Race of the specific population |
physiologicalCondition | Σ | 0..1 | CodeableConcept | The existing physiological conditions of the specific population to which this applies |
therapeuticIndication | Σ | 1..* | BackboneElement | Indication for the Medicinal Product |
diseaseSymptomProcedure | Σ | 0..1 | CodeableConcept | The disease, symptom or procedure that is the indication for treatment |
diseaseStatus | Σ | 0..1 | CodeableConcept | The status of the disease or symptom for which the indication applies |
comorbidity | Σ | 0..* | CodeableConcept | Comorbidity (concurrent condition) or co-infection as part of the indication |
intendedEffect | Σ | 0..1 | CodeableConcept | The intended effect, aim or strategy to be achieved by the indication |
duration | Σ | 0..1 | Quantity | Timing or duration information as part of the indication |
undesirableEffects | Σ | 0..* | see undesirableEffects | Information about the use of the medicinal product in relation to other therapies as part of the indication |
otherTherapy | Σ | 0..* | BackboneElement | Information about the use of the medicinal product in relation to other therapies described as part of the indication |
therapyRelationshipType | Σ | 1..1 | CodeableConcept | The type of relationship between the medicinal product indication or contraindication and another therapy |
medication[x] | Σ | 1..1 | Reference to a specific medication (active substance, medicinal product or class of products) as part of an indication or contraindication | |
medicationCodeableConcept | CodeableConcept | |||
medicationReference | Reference(MedicinalProduct | Medication | Substance | SubstanceSpecification) | |||
population | Σ | 0..* | see population | The population group to which this applies |
contraindication | Σ | 0..* | BackboneElement | Contraindication for the medicinal product |
disease | Σ | 0..1 | CodeableConcept | The disease, symptom or procedure for the contraindication |
diseaseStatus | Σ | 0..1 | CodeableConcept | The status of the disease or symptom for the contraindication |
comorbidity | Σ | 0..* | CodeableConcept | A comorbidity (concurrent condition) or coinfection |
therapeuticIndication | Σ | 0..* | see therapeuticIndication | Information about the use of the medicinal product in relation to other therapies as part of the indication |
otherTherapy | Σ | 0..* | see otherTherapy | Information about the use of the medicinal product in relation to other therapies described as part of the contraindication |
population | Σ | 0..* | see population | The population group to which this applies |
interactions | Σ | 0..* | BackboneElement | The interactions of the medicinal product with other medicinal products, or other forms of interactions |
interaction | Σ | 0..1 | string | The interaction described |
interactant | Σ | 0..* | CodeableConcept | The specific medication, food or laboratory test that interacts |
type | Σ | 0..1 | CodeableConcept | The type of the interaction |
effect | Σ | 0..1 | CodeableConcept | The effect of the interaction |
incidence | Σ | 0..1 | CodeableConcept | The incidence of the interaction |
management | Σ | 0..1 | CodeableConcept | Actions for managing the interaction |
Documentation for this format |
XML Template
<MedicinalProductClinicals xmlns="http://hl7.org/fhir"> <!-- from Resource: id, meta, implicitRules, and language --> <!-- from DomainResource: text, contained, extension, and modifierExtension --> <undesirableEffects> <!-- 0..* Describe the undesirable effects of the medicinal product --> <symptomConditionEffect><!-- 0..1 CodeableConcept The symptom, condition or undesirable effect --></symptomConditionEffect> <classification><!-- 0..1 CodeableConcept Classification of the effect --></classification> <frequencyOfOccurrence><!-- 0..1 CodeableConcept The frequency of occurrence of the effect --></frequencyOfOccurrence> <population> <!-- 0..* The population group to which this applies --> <age[x]><!-- 0..1 Range|CodeableConcept The age of the specific population --></age[x]> <gender><!-- 0..1 CodeableConcept The gender of the specific population --></gender> <race><!-- 0..1 CodeableConcept Race of the specific population --></race> <physiologicalCondition><!-- 0..1 CodeableConcept The existing physiological conditions of the specific population to which this applies --></physiologicalCondition> </population> </undesirableEffects> <therapeuticIndication> <!-- 1..* Indication for the Medicinal Product --> <diseaseSymptomProcedure><!-- 0..1 CodeableConcept The disease, symptom or procedure that is the indication for treatment --></diseaseSymptomProcedure> <diseaseStatus><!-- 0..1 CodeableConcept The status of the disease or symptom for which the indication applies --></diseaseStatus> <comorbidity><!-- 0..* CodeableConcept Comorbidity (concurrent condition) or co-infection as part of the indication --></comorbidity> <intendedEffect><!-- 0..1 CodeableConcept The intended effect, aim or strategy to be achieved by the indication --></intendedEffect> <duration><!-- 0..1 Quantity Timing or duration information as part of the indication --></duration> <undesirableEffects><!-- 0..* Content as for MedicinalProductClinicals.undesirableEffects Information about the use of the medicinal product in relation to other therapies as part of the indication --></undesirableEffects> <otherTherapy> <!-- 0..* Information about the use of the medicinal product in relation to other therapies described as part of the indication --> <therapyRelationshipType><!-- 1..1 CodeableConcept The type of relationship between the medicinal product indication or contraindication and another therapy --></therapyRelationshipType> <medication[x]><!-- 1..1 CodeableConcept|Reference(MedicinalProduct|Medication| Substance|SubstanceSpecification) Reference to a specific medication (active substance, medicinal product or class of products) as part of an indication or contraindication --></medication[x]> </otherTherapy> <population><!-- 0..* Content as for MedicinalProductClinicals.undesirableEffects.population The population group to which this applies --></population> </therapeuticIndication> <contraindication> <!-- 0..* Contraindication for the medicinal product --> <disease><!-- 0..1 CodeableConcept The disease, symptom or procedure for the contraindication --></disease> <diseaseStatus><!-- 0..1 CodeableConcept The status of the disease or symptom for the contraindication --></diseaseStatus> <comorbidity><!-- 0..* CodeableConcept A comorbidity (concurrent condition) or coinfection --></comorbidity> <therapeuticIndication><!-- 0..* Content as for MedicinalProductClinicals.therapeuticIndication Information about the use of the medicinal product in relation to other therapies as part of the indication --></therapeuticIndication> <otherTherapy><!-- 0..* Content as for MedicinalProductClinicals.therapeuticIndication.otherTherapy Information about the use of the medicinal product in relation to other therapies described as part of the contraindication --></otherTherapy> <population><!-- 0..* Content as for MedicinalProductClinicals.undesirableEffects.population The population group to which this applies --></population> </contraindication> <interactions> <!-- 0..* The interactions of the medicinal product with other medicinal products, or other forms of interactions --> <interaction value="[string]"/><!-- 0..1 The interaction described --> <interactant><!-- 0..* CodeableConcept The specific medication, food or laboratory test that interacts --></interactant> <type><!-- 0..1 CodeableConcept The type of the interaction --></type> <effect><!-- 0..1 CodeableConcept The effect of the interaction --></effect> <incidence><!-- 0..1 CodeableConcept The incidence of the interaction --></incidence> <management><!-- 0..1 CodeableConcept Actions for managing the interaction --></management> </interactions> </MedicinalProductClinicals>
JSON Template
{ "resourceType" : "MedicinalProductClinicals", // from Resource: id, meta, implicitRules, and language // from DomainResource: text, contained, extension, and modifierExtension "undesirableEffects" : [{ // Describe the undesirable effects of the medicinal product "symptomConditionEffect" : { CodeableConcept }, // The symptom, condition or undesirable effect "classification" : { CodeableConcept }, // Classification of the effect "frequencyOfOccurrence" : { CodeableConcept }, // The frequency of occurrence of the effect "population" : [{ // The population group to which this applies // age[x]: The age of the specific population. One of these 2: "ageRange" : { Range }, "ageCodeableConcept" : { CodeableConcept }, "gender" : { CodeableConcept }, // The gender of the specific population "race" : { CodeableConcept }, // Race of the specific population "physiologicalCondition" : { CodeableConcept } // The existing physiological conditions of the specific population to which this applies }] }], "therapeuticIndication" : [{ // R! Indication for the Medicinal Product "diseaseSymptomProcedure" : { CodeableConcept }, // The disease, symptom or procedure that is the indication for treatment "diseaseStatus" : { CodeableConcept }, // The status of the disease or symptom for which the indication applies "comorbidity" : [{ CodeableConcept }], // Comorbidity (concurrent condition) or co-infection as part of the indication "intendedEffect" : { CodeableConcept }, // The intended effect, aim or strategy to be achieved by the indication "duration" : { Quantity }, // Timing or duration information as part of the indication "undesirableEffects" : [{ Content as for MedicinalProductClinicals.undesirableEffects }], // Information about the use of the medicinal product in relation to other therapies as part of the indication "otherTherapy" : [{ // Information about the use of the medicinal product in relation to other therapies described as part of the indication "therapyRelationshipType" : { CodeableConcept }, // R! The type of relationship between the medicinal product indication or contraindication and another therapy // medication[x]: Reference to a specific medication (active substance, medicinal product or class of products) as part of an indication or contraindication. One of these 2: "medicationCodeableConcept" : { CodeableConcept } "medicationReference" : { Reference(MedicinalProduct|Medication|Substance| SubstanceSpecification) } }], "population" : [{ Content as for MedicinalProductClinicals.undesirableEffects.population }] // The population group to which this applies }], "contraindication" : [{ // Contraindication for the medicinal product "disease" : { CodeableConcept }, // The disease, symptom or procedure for the contraindication "diseaseStatus" : { CodeableConcept }, // The status of the disease or symptom for the contraindication "comorbidity" : [{ CodeableConcept }], // A comorbidity (concurrent condition) or coinfection "therapeuticIndication" : [{ Content as for MedicinalProductClinicals.therapeuticIndication }], // Information about the use of the medicinal product in relation to other therapies as part of the indication "otherTherapy" : [{ Content as for MedicinalProductClinicals.therapeuticIndication.otherTherapy }], // Information about the use of the medicinal product in relation to other therapies described as part of the contraindication "population" : [{ Content as for MedicinalProductClinicals.undesirableEffects.population }] // The population group to which this applies }], "interactions" : [{ // The interactions of the medicinal product with other medicinal products, or other forms of interactions "interaction" : "<string>", // The interaction described "interactant" : [{ CodeableConcept }], // The specific medication, food or laboratory test that interacts "type" : { CodeableConcept }, // The type of the interaction "effect" : { CodeableConcept }, // The effect of the interaction "incidence" : { CodeableConcept }, // The incidence of the interaction "management" : { CodeableConcept } // Actions for managing the interaction }] }
Turtle Template
@prefix fhir: <http://hl7.org/fhir/> . [ a fhir:MedicinalProductClinicals; fhir:nodeRole fhir:treeRoot; # if this is the parser root # from Resource: .id, .meta, .implicitRules, and .language # from DomainResource: .text, .contained, .extension, and .modifierExtension fhir:MedicinalProductClinicals.undesirableEffects [ # 0..* Describe the undesirable effects of the medicinal product fhir:MedicinalProductClinicals.undesirableEffects.symptomConditionEffect [ CodeableConcept ]; # 0..1 The symptom, condition or undesirable effect fhir:MedicinalProductClinicals.undesirableEffects.classification [ CodeableConcept ]; # 0..1 Classification of the effect fhir:MedicinalProductClinicals.undesirableEffects.frequencyOfOccurrence [ CodeableConcept ]; # 0..1 The frequency of occurrence of the effect fhir:MedicinalProductClinicals.undesirableEffects.population [ # 0..* The population group to which this applies # MedicinalProductClinicals.undesirableEffects.population.age[x] : 0..1 The age of the specific population. One of these 2 fhir:MedicinalProductClinicals.undesirableEffects.population.ageRange [ Range ] fhir:MedicinalProductClinicals.undesirableEffects.population.ageCodeableConcept [ CodeableConcept ] fhir:MedicinalProductClinicals.undesirableEffects.population.gender [ CodeableConcept ]; # 0..1 The gender of the specific population fhir:MedicinalProductClinicals.undesirableEffects.population.race [ CodeableConcept ]; # 0..1 Race of the specific population fhir:MedicinalProductClinicals.undesirableEffects.population.physiologicalCondition [ CodeableConcept ]; # 0..1 The existing physiological conditions of the specific population to which this applies ], ...; ], ...; fhir:MedicinalProductClinicals.therapeuticIndication [ # 1..* Indication for the Medicinal Product fhir:MedicinalProductClinicals.therapeuticIndication.diseaseSymptomProcedure [ CodeableConcept ]; # 0..1 The disease, symptom or procedure that is the indication for treatment fhir:MedicinalProductClinicals.therapeuticIndication.diseaseStatus [ CodeableConcept ]; # 0..1 The status of the disease or symptom for which the indication applies fhir:MedicinalProductClinicals.therapeuticIndication.comorbidity [ CodeableConcept ], ... ; # 0..* Comorbidity (concurrent condition) or co-infection as part of the indication fhir:MedicinalProductClinicals.therapeuticIndication.intendedEffect [ CodeableConcept ]; # 0..1 The intended effect, aim or strategy to be achieved by the indication fhir:MedicinalProductClinicals.therapeuticIndication.duration [ Quantity ]; # 0..1 Timing or duration information as part of the indication fhir:MedicinalProductClinicals.therapeuticIndication.undesirableEffects [ See MedicinalProductClinicals.undesirableEffects ], ... ; # 0..* Information about the use of the medicinal product in relation to other therapies as part of the indication fhir:MedicinalProductClinicals.therapeuticIndication.otherTherapy [ # 0..* Information about the use of the medicinal product in relation to other therapies described as part of the indication fhir:MedicinalProductClinicals.therapeuticIndication.otherTherapy.therapyRelationshipType [ CodeableConcept ]; # 1..1 The type of relationship between the medicinal product indication or contraindication and another therapy # MedicinalProductClinicals.therapeuticIndication.otherTherapy.medication[x] : 1..1 Reference to a specific medication (active substance, medicinal product or class of products) as part of an indication or contraindication. One of these 2 fhir:MedicinalProductClinicals.therapeuticIndication.otherTherapy.medicationCodeableConcept [ CodeableConcept ] fhir:MedicinalProductClinicals.therapeuticIndication.otherTherapy.medicationReference [ Reference(MedicinalProduct|Medication|Substance|SubstanceSpecification) ] ], ...; fhir:MedicinalProductClinicals.therapeuticIndication.population [ See MedicinalProductClinicals.undesirableEffects.population ], ... ; # 0..* The population group to which this applies ], ...; fhir:MedicinalProductClinicals.contraindication [ # 0..* Contraindication for the medicinal product fhir:MedicinalProductClinicals.contraindication.disease [ CodeableConcept ]; # 0..1 The disease, symptom or procedure for the contraindication fhir:MedicinalProductClinicals.contraindication.diseaseStatus [ CodeableConcept ]; # 0..1 The status of the disease or symptom for the contraindication fhir:MedicinalProductClinicals.contraindication.comorbidity [ CodeableConcept ], ... ; # 0..* A comorbidity (concurrent condition) or coinfection fhir:MedicinalProductClinicals.contraindication.therapeuticIndication [ See MedicinalProductClinicals.therapeuticIndication ], ... ; # 0..* Information about the use of the medicinal product in relation to other therapies as part of the indication fhir:MedicinalProductClinicals.contraindication.otherTherapy [ See MedicinalProductClinicals.therapeuticIndication.otherTherapy ], ... ; # 0..* Information about the use of the medicinal product in relation to other therapies described as part of the contraindication fhir:MedicinalProductClinicals.contraindication.population [ See MedicinalProductClinicals.undesirableEffects.population ], ... ; # 0..* The population group to which this applies ], ...; fhir:MedicinalProductClinicals.interactions [ # 0..* The interactions of the medicinal product with other medicinal products, or other forms of interactions fhir:MedicinalProductClinicals.interactions.interaction [ string ]; # 0..1 The interaction described fhir:MedicinalProductClinicals.interactions.interactant [ CodeableConcept ], ... ; # 0..* The specific medication, food or laboratory test that interacts fhir:MedicinalProductClinicals.interactions.type [ CodeableConcept ]; # 0..1 The type of the interaction fhir:MedicinalProductClinicals.interactions.effect [ CodeableConcept ]; # 0..1 The effect of the interaction fhir:MedicinalProductClinicals.interactions.incidence [ CodeableConcept ]; # 0..1 The incidence of the interaction fhir:MedicinalProductClinicals.interactions.management [ CodeableConcept ]; # 0..1 Actions for managing the interaction ], ...; ]
Changes since Release 3
This resource did not exist in Release 2
This analysis is available as XML or JSON.
See R3 <--> R4 Conversion Maps (status = Not Mapped)
See the Profiles & Extensions and the alternate definitions: Master Definition XML + JSON, XML Schema/Schematron + JSON Schema, ShEx (for Turtle) + see the extensions & the dependency analysis