Genomics Reporting Implementation Guide
3.0.0 - STU3 International flag

This page is part of the Genetic Reporting Implementation Guide (v3.0.0: STU3) based on FHIR (HL7® FHIR® Standard) R4. This is the current published version. For a full list of available versions, see the Directory of published versions

CodeSystem: ClinVar Evidence Level Example Codes (Experimental)

Official URL: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/clinvar-evidence-level-custom-cs Version: 3.0.0
Active as of 2024-12-12 Computable Name: ClinVarEvidenceLevelCustomCS

ClinVar contains examples of evidence level concepts that are not conflated with clinical significance. These can be found on ClinVar https://www.ncbi.nlm.nih.gov/clinvar/docs/review_status/ . These examples are informational only, for copyright information contact the relevant source.

This Code system is referenced in the content logical definition of the following value sets:

Generated Narrative: CodeSystem clinvar-evidence-level-custom-cs

This case-sensitive code system http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/clinvar-evidence-level-custom-cs defines the following codes:

CodeDisplayDefinition
4-star 4 star Supported by practice guideline
3-star 3 star Supported by expert panel review
2-star 2 star Supported by submission by multiple-submitters with documentation of criteria for assertion
1-star 1 star Single submitter providing interpretation and documentation of criteria for assertion
no-star no star submitted, no evidence