| Left: | ClinicalUseDefinition Undesirable Effect (ePI) (http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-undesirableEffect-uv-epi) |
| Right: | ClinicalUseDefinition Undesirable Effect (ePI) (http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-undesirableEffect-uv-epi) |
| Error | StructureDefinition.version | Values for version differ: '1.0.0-ballot' vs '1.0.0' |
| Information | StructureDefinition.date | Values for date differ: '2022-12-04T18:49:33+00:00' vs '2023-07-26T13:47:48+00:00' |
| Warning | StructureDefinition.fhirVersion | Values for fhirVersion differ: '5.0.0-ballot' vs '5.0.0' |
| Warning | ClinicalUseDefinition.implicitRules | Elements differ in comments: 'Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.' vs 'Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.' |
| Warning | ClinicalUseDefinition.language | Elements differ in binding.description: 'IETF language tag' vs 'IETF language tag for a human language' |
| Warning | ClinicalUseDefinition.extension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' vs 'May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' |
| Warning | ClinicalUseDefinition.modifierExtension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' vs 'May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' |
| Warning | ClinicalUseDefinition.subject | Elements differ in short: 'The medication or procedure for which this is an indication' vs 'The medication, product, substance, device, procedure etc. for which this is an indication' |
| Warning | ClinicalUseDefinition.subject | Elements differ in definition: 'The medication or procedure for which this is an indication.' vs 'The medication, product, substance, device, procedure etc. for which this is an indication.' |
| Warning | ClinicalUseDefinition.contraindication.extension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' vs 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' |
| Warning | ClinicalUseDefinition.contraindication.modifierExtension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' vs 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' |
| Warning | ClinicalUseDefinition.contraindication.otherTherapy.extension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' vs 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' |
| Warning | ClinicalUseDefinition.contraindication.otherTherapy.modifierExtension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' vs 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' |
| Warning | ClinicalUseDefinition.contraindication.otherTherapy.treatment | Elements differ in short: 'Reference to a specific medication as part of an indication or contraindication' vs 'Reference to a specific medication, substance etc. as part of an indication or contraindication' |
| Warning | ClinicalUseDefinition.contraindication.otherTherapy.treatment | Elements differ in definition: 'Reference to a specific medication (active substance, medicinal product or class of products) as part of an indication or contraindication.' vs 'Reference to a specific medication (active substance, medicinal product or class of products, biological, food etc.) as part of an indication or contraindication.' |
| Warning | ClinicalUseDefinition.indication.extension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' vs 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' |
| Warning | ClinicalUseDefinition.indication.modifierExtension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' vs 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' |
| Warning | ClinicalUseDefinition.interaction.extension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' vs 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' |
| Warning | ClinicalUseDefinition.interaction.modifierExtension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' vs 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' |
| Warning | ClinicalUseDefinition.interaction.interactant | Elements differ in short: 'The specific medication, food, substance or laboratory test that interacts' vs 'The specific medication, product, food etc. or laboratory test that interacts' |
| Warning | ClinicalUseDefinition.interaction.interactant | Elements differ in definition: 'The specific medication, food, substance or laboratory test that interacts.' vs 'The specific medication, product, food, substance etc. or laboratory test that interacts.' |
| Warning | ClinicalUseDefinition.interaction.interactant.extension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' vs 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' |
| Warning | ClinicalUseDefinition.interaction.interactant.modifierExtension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' vs 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' |
| Warning | ClinicalUseDefinition.interaction.interactant.item[x] | Elements differ in short: 'The specific medication, food or laboratory test that interacts' vs 'The specific medication, product, food etc. or laboratory test that interacts' |
| Warning | ClinicalUseDefinition.interaction.interactant.item[x] | Elements differ in definition: 'The specific medication, food or laboratory test that interacts.' vs 'The specific medication, product, food, substance etc. or laboratory test that interacts.' |
| Warning | ClinicalUseDefinition.interaction.interactant.item[x] | Elements differ in binding.description: 'An interactant - a substance that may have an clinically significant effect on another.' vs 'An interactant - a substance that may have a clinically significant effect on another.' |
| Warning | ClinicalUseDefinition.undesirableEffect.extension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' vs 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' |
| Warning | ClinicalUseDefinition.undesirableEffect.modifierExtension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' vs 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' |
| Warning | ClinicalUseDefinition.warning.extension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' vs 'May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' |
| Warning | ClinicalUseDefinition.warning.modifierExtension | Elements differ in definition: 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' vs 'May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).' |
| Name | Value | Comments | |
|---|---|---|---|
 abstract | false | ||
| baseDefinition | http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition | ||
| copyright | |||
| date | 2022-12-04T18:49:33+00:00 | 2023-07-26T13:47:48+00:00 |
|
| description | ClinicalUseDefinition Undesirable Effect (ePI) | ||
| experimental | |||
| fhirVersion | 5.0.0-ballot | 5.0.0 |
|
| jurisdiction | |||
 jurisdiction[0] | http://unstats.un.org/unsd/methods/m49/m49.htm#001 | ||
| kind | resource | ||
| name | ClinicalUseDefinitionUndesirableEffectUvEpi | ||
| publisher | HL7 International - Biomedical Research & Regulation Work Group |
| |
| purpose | |||
| status | active | ||
| title | ClinicalUseDefinition Undesirable Effect (ePI) | ||
| type | ClinicalUseDefinition | ||
| url | http://hl7.org/fhir/uv/emedicinal-product-info/StructureDefinition/ClinicalUseDefinition-undesirableEffect-uv-epi | ||
| version | 1.0.0-ballot | 1.0.0 |
|
| Name | L Flags | L Card. | L Type | L Description & Constraints | R Flags | R Card. | L Type | L Description & Constraints | Comments | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 ClinicalUseDefinition | C | 0..* | ClinicalUseDefinition | A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure | C | 0..* | ClinicalUseDefinition | A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure | |||||
 id | Σ | 0..1 | id | Logical id of this artifact | Σ | 0..1 | id | Logical id of this artifact | |||||
| meta | Σ | 0..1 | Meta | Metadata about the resource | Σ | 0..1 | Meta | Metadata about the resource | |||||
| implicitRules | ?!Σ | 0..1 | uri | A set of rules under which this content was created | ?!Σ | 0..1 | uri | A set of rules under which this content was created |
| ||||
| language | 0..1 | code | Language of the resource content Binding: ?? (preferred): IETF language tag
| 0..1 | code | Language of the resource content Binding: ?? (required): IETF language tag for a human language |
| ||||||
| text | 0..1 | Narrative | Text summary of the resource, for human interpretation | 0..1 | Narrative | Text summary of the resource, for human interpretation | |||||||
| contained | 0..* | Resource | Contained, inline Resources | 0..* | Resource | Contained, inline Resources | |||||||
 extension | 0..* | Extension | Additional content defined by implementations | 0..* | Extension | Additional content defined by implementations |
| ||||||
 modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored | ?!Σ | 0..* | Extension | Extensions that cannot be ignored |
| ||||
| identifier | Σ | 0..* | Identifier | Business identifier for this clinical use. | Σ | 0..* | Identifier | Business identifier for this clinical use. | |||||
| type | Σ | 1..1 | code | indication | contraindication | interaction | undesirable-effect | warning Binding: ?? (required): Overall defining type of this clinical use definition. Required Pattern: undesirable-effect | Σ | 1..1 | code | indication | contraindication | interaction | undesirable-effect | warning Binding: ?? (required): Overall defining type of this clinical use definition. Required Pattern: undesirable-effect | |||||
| category | Σ | 0..* | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ?? (preferred): A categorisation for a clinical use information item. | Σ | 0..* | CodeableConcept | A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose" Binding: ?? (preferred): A categorisation for a clinical use information item. | |||||
| subject | Σ | 1..* | Reference(MedicinalProductDefinition (ePI)) | The medication or procedure for which this is an indication | Σ | 1..* | Reference(MedicinalProductDefinition (ePI)) | The medication, product, substance, device, procedure etc. for which this is an indication |
| ||||
| status | Σ | 0..1 | CodeableConcept | Defines whether this clinical use is draft, active or retired Binding: ?? (preferred): The lifecycle status of an artifact. | Σ | 0..1 | CodeableConcept | Defines whether this clinical use is draft, active or retired Binding: ?? (preferred): The lifecycle status of an artifact. | |||||
 contraindication | Σ | 0..0 | ΣC | 0..0 | |||||||||
 id | 0..1 | string | Unique id for inter-element referencing | 0..1 | string | Unique id for inter-element referencing | |||||||
| extension | 0..* | Extension | Additional content defined by implementations | 0..* | Extension | Additional content defined by implementations |
| ||||||
| modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized |
| ||||
| diseaseSymptomProcedure | Σ | 0..1 | CodeableReference(ObservationDefinition) | The situation that is being documented as contraindicating against this item Binding: ?? (example): A symptom, disease or procedure. | Σ | 0..1 | CodeableReference(ObservationDefinition) | The situation that is being documented as contraindicating against this item Binding: ?? (example): A symptom, disease or procedure. | |||||
| diseaseStatus | Σ | 0..1 | CodeableReference(ObservationDefinition) | The status of the disease or symptom for the contraindication Binding: ?? (example): The status of a disease or symptom. | Σ | 0..1 | CodeableReference(ObservationDefinition) | The status of the disease or symptom for the contraindication Binding: ?? (example): The status of a disease or symptom. | |||||
| comorbidity | Σ | 0..* | CodeableReference(ObservationDefinition) | A comorbidity (concurrent condition) or coinfection Binding: ?? (example): A symptom, disease or procedure. | Σ | 0..* | CodeableReference(ObservationDefinition) | A comorbidity (concurrent condition) or coinfection Binding: ?? (example): A symptom, disease or procedure. | |||||
| indication | Σ | 0..* | Reference(ClinicalUseDefinition) | The indication which this is a contraidication for | Σ | 0..* | Reference(ClinicalUseDefinition) | The indication which this is a contraidication for | |||||
| otherTherapy | Σ | 0..* | BackboneElement | Information about use of the product in relation to other therapies described as part of the contraindication | Σ | 0..* | BackboneElement | Information about use of the product in relation to other therapies described as part of the contraindication | |||||
| id | 0..1 | string | Unique id for inter-element referencing | 0..1 | string | Unique id for inter-element referencing | |||||||
| extension | 0..* | Extension | Additional content defined by implementations | 0..* | Extension | Additional content defined by implementations |
| ||||||
| modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized |
| ||||
| relationshipType | Σ | 1..1 | CodeableConcept | The type of relationship between the product indication/contraindication and another therapy Binding: ?? (preferred): Classification of relationship between a therapy and a contraindication or an indication. | Σ | 1..1 | CodeableConcept | The type of relationship between the product indication/contraindication and another therapy Binding: ?? (preferred): Classification of relationship between a therapy and a contraindication or an indication. | |||||
| treatment | Σ | 1..1 | CodeableReference(MedicinalProductDefinition | Medication | Substance | SubstanceDefinition | ActivityDefinition) | Reference to a specific medication as part of an indication or contraindication Binding: ?? (example): A therapy. | Σ | 1..1 | CodeableReference(MedicinalProductDefinition | Medication | Substance | SubstanceDefinition | NutritionProduct | BiologicallyDerivedProduct | ActivityDefinition) | Reference to a specific medication, substance etc. as part of an indication or contraindication Binding: ?? (example): A therapy. |
| ||||
| applicability | 0..1 | Expression | An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements |
| |||||||||
| indication | Σ | 0..0 | ΣC | 0..0 | |||||||||
| id | 0..1 | string | Unique id for inter-element referencing | 0..1 | string | Unique id for inter-element referencing | |||||||
| extension | 0..* | Extension | Additional content defined by implementations | 0..* | Extension | Additional content defined by implementations |
| ||||||
| modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized |
| ||||
| diseaseSymptomProcedure | Σ | 0..1 | CodeableReference(ObservationDefinition) | The situation that is being documented as an indicaton for this item Binding: ?? (example): A symptom, disease or procedure. | Σ | 0..1 | CodeableReference(ObservationDefinition) | The situation that is being documented as an indicaton for this item Binding: ?? (example): A symptom, disease or procedure. | |||||
| diseaseStatus | Σ | 0..1 | CodeableReference(ObservationDefinition) | The status of the disease or symptom for the indication Binding: ?? (example): The status of a disease or symptom. | Σ | 0..1 | CodeableReference(ObservationDefinition) | The status of the disease or symptom for the indication Binding: ?? (example): The status of a disease or symptom. | |||||
| comorbidity | Σ | 0..* | CodeableReference(ObservationDefinition) | A comorbidity or coinfection as part of the indication Binding: ?? (example): A symptom, disease or procedure. | Σ | 0..* | CodeableReference(ObservationDefinition) | A comorbidity or coinfection as part of the indication Binding: ?? (example): A symptom, disease or procedure. | |||||
| intendedEffect | Σ | 0..1 | CodeableReference(ObservationDefinition) | The intended effect, aim or strategy to be achieved Binding: ?? (preferred): The overall intended use of a product. | Σ | 0..1 | CodeableReference(ObservationDefinition) | The intended effect, aim or strategy to be achieved Binding: ?? (preferred): The overall intended use of a product. | |||||
| duration[x] | Σ | 0..1 | Range, string | Timing or duration information | Σ | 0..1 | Range, string | Timing or duration information | |||||
| undesirableEffect | Σ | 0..* | Reference(ClinicalUseDefinition) | An unwanted side effect or negative outcome of the subject of this resource when being used for this indication | Σ | 0..* | Reference(ClinicalUseDefinition) | An unwanted side effect or negative outcome of the subject of this resource when being used for this indication | |||||
 otherTherapy | Σ | 0..* | See otherTherapy (ClinicalUseDefinition) | The use of the medicinal product in relation to other therapies described as part of the indication | Σ | 0..* | See otherTherapy (ClinicalUseDefinition) | The use of the medicinal product in relation to other therapies described as part of the indication | |||||
| applicability | 0..1 | Expression | An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements |
| |||||||||
| interaction | Σ | 0..0 | ΣC | 0..0 | |||||||||
| id | 0..1 | string | Unique id for inter-element referencing | 0..1 | string | Unique id for inter-element referencing | |||||||
| extension | 0..* | Extension | Additional content defined by implementations | 0..* | Extension | Additional content defined by implementations |
| ||||||
| modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized |
| ||||
| interactant | Σ | 0..* | BackboneElement | The specific medication, food, substance or laboratory test that interacts | Σ | 0..* | BackboneElement | The specific medication, product, food etc. or laboratory test that interacts |
| ||||
| id | 0..1 | string | Unique id for inter-element referencing | 0..1 | string | Unique id for inter-element referencing | |||||||
| extension | 0..* | Extension | Additional content defined by implementations | 0..* | Extension | Additional content defined by implementations |
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| modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized |
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| item[x] | Σ | 1..1 | Reference(MedicinalProductDefinition | Medication | Substance | ObservationDefinition), CodeableConcept | The specific medication, food or laboratory test that interacts Binding: ?? (example): An interactant - a substance that may have an clinically significant effect on another. | Σ | 1..1 | Reference(MedicinalProductDefinition | Medication | Substance | NutritionProduct | BiologicallyDerivedProduct | ObservationDefinition), CodeableConcept | The specific medication, product, food etc. or laboratory test that interacts Binding: ?? (example): An interactant - a substance that may have a clinically significant effect on another. |
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| type | Σ | 0..1 | CodeableConcept | The type of the interaction e.g. drug-drug interaction, drug-lab test interaction Binding: ?? (example): A categorisation for an interaction between two substances. | Σ | 0..1 | CodeableConcept | The type of the interaction e.g. drug-drug interaction, drug-lab test interaction Binding: ?? (example): A categorisation for an interaction between two substances. | |||||
| effect | Σ | 0..1 | CodeableReference(ObservationDefinition) | The effect of the interaction, for example "reduced gastric absorption of primary medication" Binding: ?? (example): A interaction effect of clinical use of a medication or other substance. | Σ | 0..1 | CodeableReference(ObservationDefinition) | The effect of the interaction, for example "reduced gastric absorption of primary medication" Binding: ?? (example): A interaction effect of clinical use of a medication or other substance. | |||||
| incidence | Σ | 0..1 | CodeableConcept | The incidence of the interaction, e.g. theoretical, observed Binding: ?? (example): A categorisation for incidence of occurence of an interaction. | Σ | 0..1 | CodeableConcept | The incidence of the interaction, e.g. theoretical, observed Binding: ?? (example): A categorisation for incidence of occurence of an interaction. | |||||
| management | Σ | 0..* | CodeableConcept | Actions for managing the interaction Binding: ?? (example): A type of management for an interaction of a medication or other substance. | Σ | 0..* | CodeableConcept | Actions for managing the interaction Binding: ?? (example): A type of management for an interaction of a medication or other substance. | |||||
| population | Σ | 0..* | Reference(Group) | The population group to which this applies | Σ | 0..* | Reference(Group) | The population group to which this applies | |||||
| undesirableEffect | Σ | 1..1 | BackboneElement | A possible negative outcome from the use of this treatment | ΣC | 1..1 | BackboneElement | A possible negative outcome from the use of this treatment | |||||
| id | 0..1 | string | Unique id for inter-element referencing | 0..1 | string | Unique id for inter-element referencing | |||||||
| extension | 0..* | Extension | Additional content defined by implementations | 0..* | Extension | Additional content defined by implementations |
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| modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized |
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| symptomConditionEffect | Σ | 0..1 | CodeableReference(ObservationDefinition) | The situation in which the undesirable effect may manifest. Binding: ?? (example): An undesirable effect of clinical use. | Σ | 0..1 | CodeableReference(ObservationDefinition) | The situation in which the undesirable effect may manifest. Binding: ?? (example): An undesirable effect of clinical use. | |||||
| classification | Σ | 0..1 | CodeableConcept | High level classification of the effect. Binding: ?? (example): A categorisation for an undesirable effect. | Σ | 0..1 | CodeableConcept | High level classification of the effect. Binding: ?? (example): A categorisation for an undesirable effect. | |||||
| frequencyOfOccurrence | Σ | 0..1 | CodeableConcept | How often the effect is seen. Binding: ?? (example): A categorisation for a frequency of occurence of an undesirable effect. | Σ | 0..1 | CodeableConcept | How often the effect is seen. Binding: ?? (example): A categorisation for a frequency of occurence of an undesirable effect. | |||||
| warning | Σ | 0..0 | ΣC | 0..0 | |||||||||
| id | 0..1 | string | Unique id for inter-element referencing | 0..1 | string | Unique id for inter-element referencing | |||||||
| extension | 0..* | Extension | Additional content defined by implementations | 0..* | Extension | Additional content defined by implementations |
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| modifierExtension | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized | ?!Σ | 0..* | Extension | Extensions that cannot be ignored even if unrecognized |
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| description | Σ | 0..1 | markdown | A textual definition of this warning, with formatting | Σ | 0..1 | markdown | A textual definition of this warning, with formatting | |||||
| code | Σ | 0..1 | CodeableConcept | A coded or unformatted textual definition of this warning Binding: ?? (example): Classification of warning type. | Σ | 0..1 | CodeableConcept | A coded or unformatted textual definition of this warning Binding: ?? (example): Classification of warning type. | |||||
| library | Σ | 0..* | canonical(Library) | Logic used by the clinical use definition |
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| Documentation for this format | |||||||||||||