{
  "types": [
    "ResearchSubject"
  ],
  "ResearchSubject": {
    "elements": {
      "ResearchSubject.status": {
        "binding-valueset-changed": true,
        "binding-status": "changed",
        "old-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/research-subject-status|4.3.0",
          "strength": "required"
        },
        "new-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/publication-status|5.0.0",
          "strength": "required"
        }
      },
      "ResearchSubject.progress": {
        "status": "new"
      },
      "ResearchSubject.progress.type": {
        "status": "new"
      },
      "ResearchSubject.progress.subjectState": {
        "status": "new"
      },
      "ResearchSubject.progress.milestone": {
        "status": "new"
      },
      "ResearchSubject.progress.reason": {
        "status": "new"
      },
      "ResearchSubject.progress.startDate": {
        "status": "new"
      },
      "ResearchSubject.progress.endDate": {
        "status": "new"
      },
      "ResearchSubject.subject": {
        "status": "new"
      },
      "ResearchSubject.assignedComparisonGroup": {
        "status": "new"
      },
      "ResearchSubject.actualComparisonGroup": {
        "status": "new"
      },
      "ResearchSubject.consent": {
        "old-max": "1",
        "new-max": "*"
      },
      "ResearchSubject.individual": {
        "status": "deleted"
      },
      "ResearchSubject.assignedArm": {
        "status": "deleted"
      },
      "ResearchSubject.actualArm": {
        "status": "deleted"
      }
    },
    "status": "changed"
  }
}