Oral Chemotherapy Example - Manufactured Product - Xeloda - includes a reference to a substance in ingredient element

@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

[a fhir:Medication ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "medexample015"] ; # 
  fhir:text [
     fhir:status [ fhir:v "generated" ] ;
     fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Medication</b><a name=\"medexample015\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource Medication &quot;medexample015&quot; </p></div><p><b>code</b>: capecitabine 500 MG Oral Tablet [Xeloda] <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.4.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#213293)</span></p><p><b>marketingAuthorizationHolder</b>: <a name=\"mmanu\"> </a></p><blockquote><p/><p><a name=\"mmanu\"> </a></p><p><b>name</b>: Medication Manufacturer</p></blockquote><p><b>doseForm</b>: Tablet dose form (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#385055001)</span></p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a name=\"sub04\"> </a><blockquote><p/><p><a name=\"sub04\"> </a></p><p><b>instance</b>: false</p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td>Capecitabine (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#386906001)</span></td></tr></table></blockquote></td></tr></table><p><b>strength</b>: 500 mg<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg = 'mg')</span>/1(unit TAB from http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm)<span style=\"background: LightGoldenRodYellow\"> (Details: http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm code TAB = 'Tablet')</span></p></blockquote><h3>Batches</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>LotNumber</b></td><td><b>ExpirationDate</b></td></tr><tr><td style=\"display: none\">*</td><td>9494788</td><td>2017-05-22</td></tr></table></div>"
  ] ; # 
  fhir:contained ( [
     a fhir:Organization ;
     fhir:id [ fhir:v "mmanu" ] ;
     fhir:name [ fhir:v "Medication Manufacturer" ]
  ] [
     a fhir:Substance ;
     fhir:id [ fhir:v "sub04" ] ;
     fhir:instance [ fhir:v "false"^^xsd:boolean ] ;
     fhir:code [
       fhir:concept [
         fhir:coding ( [
           a sct:386906001 ;
           fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
           fhir:code [ fhir:v "386906001" ] ;
           fhir:display [ fhir:v "Capecitabine (substance)" ]
         ] )
       ]
     ]
  ] ) ; # 
  fhir:code [
     fhir:coding ( [
       fhir:system [ fhir:v "http://www.nlm.nih.gov/research/umls/rxnorm"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "213293" ] ;
       fhir:display [ fhir:v "capecitabine 500 MG Oral Tablet [Xeloda]" ]
     ] )
  ] ; # 
  fhir:marketingAuthorizationHolder [
     fhir:reference [ fhir:v "#mmanu" ]
  ] ; # 
  fhir:doseForm [
     fhir:coding ( [
       a sct:385055001 ;
       fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "385055001" ] ;
       fhir:display [ fhir:v "Tablet dose form (qualifier value)" ]
     ] )
  ] ; # 
  fhir:ingredient ( [
     fhir:item [
       fhir:reference [
         fhir:reference [ fhir:v "#sub04" ]
       ]
     ] ;
     fhir:strength [
       a fhir:Ratio ;
       fhir:numerator [
         fhir:value [ fhir:v "500"^^xsd:decimal ] ;
         fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "mg" ]
       ] ;
       fhir:denominator [
         fhir:value [ fhir:v "1"^^xsd:decimal ] ;
         fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "TAB" ]
       ]
     ]
  ] ) ; # 
  fhir:batch [
     fhir:lotNumber [ fhir:v "9494788" ] ;
     fhir:expirationDate [ fhir:v "2017-05-22"^^xsd:date ]
  ]] . # 

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