Medicinalproductdefinition-example-equilidem-using-ingredient-and-auth.ttl

Simple version of a product (more than basic), only using MedicinalProductDefinition, Ingredient and RegulatedAuthorization

@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/MedicinalProductDefinition/equilidem-with-ing-and-auth> a fhir:MedicinalProductDefinition;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "equilidem-with-ing-and-auth"];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><p><b>id</b>: equilidem-with-ing-and-auth</p><p><b>identifier</b>: id: Equilidem25</p><p><b>combinedPharmaceuticalDoseForm</b>: <span>tablet</span></p><p><b>indication</b>: Prevention of venous thromboembolic events (VTE) in adult patients who have undergone elective hip or knee replacement surgery. Prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (NVAF), with one or more risk factors, such as prior stroke or transient ischaemic attack (TIA); age ≥ 75 years; hypertension; diabetes mellitus; symptomatic heart failure (NYHA Class &gt;= II). Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevention of recurrent DVT and PE in adults.</p><p><b>legalStatusOfSupply</b>: <span>Prescription only medicine</span></p><p><b>classification</b>: <span>B01A</span></p><p><b>ingredient</b>: </p><ul><li><a> </a></li><li><a> </a></li></ul><blockquote><p><b>id</b>: EquilidoniumPhosphate</p><p><b>role</b>: <span>active</span></p><blockquote><p><b>substance</b></p><p><b>code</b>: <span>Equilidonium Phosphate</span></p><h3>Strengths</h3><table><tr><td>-</td><td><b>Presentation</b></td></tr><tr><td>*</td><td>22 ml/1 tablet</td></tr></table></blockquote></blockquote><blockquote><p><b>id</b>: CalciumCarbonate</p><p><b>role</b>: <span>excipient</span></p><blockquote><p><b>substance</b></p><p><b>code</b>: <span>Calcium Carbonate</span></p><h3>Strengths</h3><table><tr><td>-</td><td><b>Presentation</b></td></tr><tr><td>*</td><td>3 ml/1 tablet</td></tr></table></blockquote></blockquote><h3>Names</h3><table><tr><td>-</td><td><b>ProductName</b></td></tr><tr><td>*</td><td>Equilidem 2.5 mg film-coated tablets</td></tr></table><h3>CrossReferences</h3><table><tr><td>-</td><td><b>Product</b></td></tr><tr><td>*</td><td/></tr></table><h3>ManufacturingBusinessOperations</h3><table><tr><td>-</td><td><b>Manufacturer</b></td></tr><tr><td>*</td><td><span>EquiliDrugCo Processing Inc.</span></td></tr></table></div>"
  ];
  fhir:DomainResource.contained [
     a fhir:Ingredient;
     fhir:index 0;
     fhir:Resource.id [ fhir:value "EquilidoniumPhosphate" ];
     fhir:Ingredient.role [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://example.org.uk/fhir/ingredientType" ];
         fhir:Coding.code [ fhir:value "active" ]
       ]
     ];
     fhir:Ingredient.substance [
       fhir:Ingredient.substance.codeCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://example.org.uk/fhir/substances" ];
           fhir:Coding.code [ fhir:value "123456" ];
           fhir:Coding.display [ fhir:value "Equilidonium Phosphate" ]
         ]
       ];
       fhir:Ingredient.substance.strength [
         fhir:index 0;
         fhir:Ingredient.substance.strength.presentation [
           fhir:Ratio.numerator [
             fhir:Quantity.value [ fhir:value "22"^^xsd:decimal ];
             fhir:Quantity.unit [ fhir:value "ml" ]
           ];
           fhir:Ratio.denominator [
             fhir:Quantity.value [ fhir:value "1"^^xsd:decimal ];
             fhir:Quantity.unit [ fhir:value "tablet" ]
           ]
         ]
       ]
     ]
  ], [
     a fhir:Ingredient;
     fhir:index 1;
     fhir:Resource.id [ fhir:value "CalciumCarbonate" ];
     fhir:Ingredient.role [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://example.org.uk/fhir/ingredientType" ];
         fhir:Coding.code [ fhir:value "excipient" ]
       ]
     ];
     fhir:Ingredient.substance [
       fhir:Ingredient.substance.codeCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://example.org.uk/fhir/substances" ];
           fhir:Coding.code [ fhir:value "456789" ];
           fhir:Coding.display [ fhir:value "Calcium Carbonate" ]
         ]
       ];
       fhir:Ingredient.substance.strength [
         fhir:index 0;
         fhir:Ingredient.substance.strength.presentation [
           fhir:Ratio.numerator [
             fhir:Quantity.value [ fhir:value "3"^^xsd:decimal ];
             fhir:Quantity.unit [ fhir:value "ml" ]
           ];
           fhir:Ratio.denominator [
             fhir:Quantity.value [ fhir:value "1"^^xsd:decimal ];
             fhir:Quantity.unit [ fhir:value "tablet" ]
           ]
         ]
       ]
     ]
  ];
  fhir:MedicinalProductDefinition.identifier [
     fhir:index 0;
     fhir:Identifier.system [ fhir:value "http://example.org.uk/fhir/product" ];
     fhir:Identifier.value [ fhir:value "Equilidem25" ]
  ];
  fhir:MedicinalProductDefinition.combinedPharmaceuticalDoseForm [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://example.org.uk/fhir/dosefom" ];
       fhir:Coding.code [ fhir:value "tablet" ]
     ]
  ];
  fhir:MedicinalProductDefinition.indication [ fhir:value "Prevention of venous thromboembolic events (VTE) in adult patients who have undergone elective hip or knee replacement surgery. Prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (NVAF), with one or more risk factors, such as prior stroke or transient ischaemic attack (TIA); age ≥ 75 years; hypertension; diabetes mellitus; symptomatic heart failure (NYHA Class >= II). Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevention of recurrent DVT and PE in adults."];
  fhir:MedicinalProductDefinition.legalStatusOfSupply [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://example.org.uk/fhir/legalstatusofsupply" ];
       fhir:Coding.code [ fhir:value "POM" ];
       fhir:Coding.display [ fhir:value "Prescription only medicine" ]
     ]
  ];
  fhir:MedicinalProductDefinition.classification [
     fhir:index 0;
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://www.whocc.no/atc/example" ];
       fhir:Coding.code [ fhir:value "B01A" ]
     ]
  ];
  fhir:MedicinalProductDefinition.ingredient [
     fhir:index 0;
     fhir:Reference.reference [ fhir:value "#EquilidoniumPhosphate" ]
  ], [
     fhir:index 1;
     fhir:Reference.reference [ fhir:value "#CalciumCarbonate" ]
  ];
  fhir:MedicinalProductDefinition.name [
     fhir:index 0;
     fhir:MedicinalProductDefinition.name.productName [ fhir:value "Equilidem 2.5 mg film-coated tablets" ]
  ];
  fhir:MedicinalProductDefinition.crossReference [
     fhir:index 0;
     fhir:MedicinalProductDefinition.crossReference.product [
       fhir:CodeableReference.reference [
         fhir:link <http://hl7.org/fhir/MedicinalProductDefinition/genericEquilidonium>;
         fhir:Reference.reference [ fhir:value "MedicinalProductDefinition/genericEquilidonium" ]
       ]
     ]
  ];
  fhir:MedicinalProductDefinition.manufacturingBusinessOperation [
     fhir:index 0;
     fhir:MedicinalProductDefinition.manufacturingBusinessOperation.manufacturer [
       fhir:index 0;
       fhir:Reference.display [ fhir:value "EquiliDrugCo Processing Inc." ]
     ]
  ] .

<http://hl7.org/fhir/MedicinalProductDefinition/genericEquilidonium> a fhir:MedicinalProductDefinition .

# - ontology header ------------------------------------------------------------

<http://hl7.org/fhir/MedicinalProductDefinition/equilidem-with-ing-and-auth.ttl> a owl:Ontology;
  owl:imports fhir:fhir.ttl;
  owl:versionIRI <http://build.fhir.org/MedicinalProductDefinition/equilidem-with-ing-and-auth.ttl> .

# -------------------------------------------------------------------------------------