This page is part of the FHIR Specification (v4.2.0: R5 Preview #1). The current version which supercedes this version is 5.0.0. For a full list of available versions, see the Directory of published versions . Page versions: R5 R4B R4 R3
Clinical Decision Support Work Group | Maturity Level: N/A | Standards Status: Informative | Compartments: Device, Patient, Practitioner |
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Drug-drug interaction between prescription and medication statement
@prefix fhir: <http://hl7.org/fhir/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- <http://hl7.org/fhir/DetectedIssue/ddi> a fhir:DetectedIssue; fhir:nodeRole fhir:treeRoot; fhir:Resource.id [ fhir:value "ddi"]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n <p><b>Severity: High</b> - Risk of internal bleeding</p>\n <p>Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding.</p>\n <ul>\n <li><a href=\"MedicationUsage/tylenol\">500 mg Acetaminophen tablet 1/day, PRN since 2010</a></li>\n <li><a href=\"MedicationRequest/warfarin\">Warfarin 1 MG TAB prescribed Jan. 5, 2014</a></li>\n </ul>\n <p>Mitigation: Jan 5, 2014 by Dr. Adam Careful: </p>\n <p>Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring</p>\n </div>" ]; fhir:DetectedIssue.status [ fhir:value "final"]; fhir:DetectedIssue.code [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-ActCode" ]; fhir:Coding.code [ fhir:value "DRG" ]; fhir:Coding.display [ fhir:value "Drug Interaction Alert" ] ] ]; fhir:DetectedIssue.severity [ fhir:value "high"]; fhir:DetectedIssue.identifiedDateTime [ fhir:value "2014-01-05"^^xsd:date]; fhir:DetectedIssue.author [ fhir:link <http://hl7.org/fhir/Device/software>; fhir:Reference.reference [ fhir:value "Device/software" ] ]; fhir:DetectedIssue.implicated [ fhir:index 0; fhir:link <http://hl7.org/fhir/MedicationUsage/example001>; fhir:Reference.reference [ fhir:value "MedicationUsage/example001" ]; fhir:Reference.display [ fhir:value "500 mg Acetaminophen tablet 1/day, PRN since 2010" ] ], [ fhir:index 1; fhir:link <http://hl7.org/fhir/MedicationRequest/medrx0331>; fhir:Reference.reference [ fhir:value "MedicationRequest/medrx0331" ]; fhir:Reference.display [ fhir:value "Warfarin 1 MG TAB prescribed Jan. 15, 2015" ] ]; fhir:DetectedIssue.detail [ fhir:value "Risk of internal bleeding. Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding."]; fhir:DetectedIssue.mitigation [ fhir:index 0; fhir:DetectedIssue.mitigation.action [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-ActCode" ]; fhir:Coding.code [ fhir:value "13" ]; fhir:Coding.display [ fhir:value "Stopped Concurrent Therapy" ] ]; fhir:CodeableConcept.text [ fhir:value "Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring" ] ]; fhir:DetectedIssue.mitigation.date [ fhir:value "2014-01-05"^^xsd:date ]; fhir:DetectedIssue.mitigation.author [ fhir:link <http://hl7.org/fhir/Practitioner/example>; fhir:Reference.reference [ fhir:value "Practitioner/example" ]; fhir:Reference.display [ fhir:value "Dr. Adam Careful" ] ] ] . <http://hl7.org/fhir/Device/software> a fhir:Device . <http://hl7.org/fhir/MedicationUsage/example001> a fhir:MedicationUsage . <http://hl7.org/fhir/MedicationRequest/medrx0331> a fhir:MedicationRequest . <http://hl7.org/fhir/Practitioner/example> a fhir:Practitioner . # - ontology header ------------------------------------------------------------ <http://hl7.org/fhir/DetectedIssue/ddi.ttl> a owl:Ontology; owl:imports fhir:fhir.ttl; owl:versionIRI <http://build.fhir.org/DetectedIssue/ddi.ttl> . # -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.