Extensions for Using Data Elements from FHIR R5 in FHIR R4
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Extensions for Using Data Elements from FHIR R5 in FHIR R4 - Downloaded Version null See the Directory of published versions

Resource Profile: Profile_R5_MedicationKnowledge_R4 - Detailed Descriptions

Page standards status: Trial-use Maturity Level: 0

Definitions for the profile-MedicationKnowledge resource profile.

Guidance on how to interpret the contents of this table can be foundhere

0. MedicationKnowledge
Definition

Information about a medication that is used to support knowledge.

ShortDefinition of Medication Knowledge
Control0..*
Is Modifierfalse
Summaryfalse
Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
dom-6: A resource should have narrative for robust management (text.`div`.exists())
dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
dom-6: A resource should have narrative for robust management (text.`div`.exists())
2. MedicationKnowledge.implicitRules
Definition

A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

ShortA set of rules under which this content was created
Comments

Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.

Control0..1
Typeuri
Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Summarytrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
4. MedicationKnowledge.extension
Definition

An Extension


May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

ShortExtensionAdditional content defined by implementations
Comments

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Control0..*
TypeExtension
Is Modifierfalse
Summaryfalse
Alternate Namesextensions, user content
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
SlicingThis element introduces a set of slices on MedicationKnowledge.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
  • value @ url
  • 6. MedicationKnowledge.extension:identifier
    Slice Nameidentifier
    Definition

    R5: MedicationKnowledge.identifier (new:Identifier)

    ShortR5: Business identifier for this medication (new)
    Comments

    Element MedicationKnowledge.identifier has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.identifier has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element). An externally-defined extension that has been mapped as the representation of FHIR R5 element MedicationKnowledge.identifier: http://hl7.org/fhir/StructureDefinition/artifact-identifier. This is a business identifier, not a resource identifier (see discussion).

    Control0..*
    TypeExtension(Artifact Identifier) (Extension Type: Identifier)
    Is Modifierfalse
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    8. MedicationKnowledge.extension:author
    Slice Nameauthor
    Definition

    R5: MedicationKnowledge.author (new:Reference(Organization))

    ShortR5: Creator or owner of the knowledge or information about the medication (new)
    Comments

    Element MedicationKnowledge.author has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.author has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element). An externally-defined extension that has been mapped as the representation of FHIR R5 element MedicationKnowledge.author: http://hl7.org/fhir/StructureDefinition/artifact-author.

    Control0..1
    TypeExtension(Artifact Author) (Extension Type: ContactDetail)
    Is Modifierfalse
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    10. MedicationKnowledge.extension:intendedJurisdiction
    Slice NameintendedJurisdiction
    Definition

    R5: MedicationKnowledge.intendedJurisdiction (new:CodeableConcept)

    ShortR5: Codes that identify the different jurisdictions for which the information of this resource was created (new)
    Comments

    Element MedicationKnowledge.intendedJurisdiction has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.intendedJurisdiction has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element). The codes could have varying granularity from a country or group of countries down to a specific district.

    Control0..*
    This element is affected by the following invariants: ele-1
    TypeExtension(R5: Codes that identify the different jurisdictions for which the information of this resource was created (new)) (Extension Type: CodeableConcept)
    Is Modifierfalse
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    12. MedicationKnowledge.extension:storageGuideline
    Slice NamestorageGuideline
    Definition

    R5: MedicationKnowledge.storageGuideline (new:BackboneElement)

    ShortR5: How the medication should be stored (new)
    Comments

    Element MedicationKnowledge.storageGuideline has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.storageGuideline has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

    Control0..*
    This element is affected by the following invariants: ele-1
    TypeExtension(R5: How the medication should be stored (new)) (Complex Extension)
    Is Modifierfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    14. MedicationKnowledge.modifierExtension
    Definition

    May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

    Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

    ShortExtensions that cannot be ignored
    Comments

    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

    Control0..*
    TypeExtension
    Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
    Summaryfalse
    Requirements

    Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

    Alternate Namesextensions, user content
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    16. MedicationKnowledge.status
    Definition

    A code to indicate if the medication is in active use. The status refers to the validity about the information of the medication and not to its medicinal properties.

    Shortactive | inactive | entered-in-error
    Comments

    This status is intended to identify if the medication in a local system is in active use within a drug database or inventory. For example, a pharmacy system may create a new drug file record for a compounded product "ABC Hospital Special Cream" with an active status. At some point in the future, it may be determined that the drug record was created with an error and the status is changed to "entered in error". This status is not intended to specify if a medication is part of a particular formulary. It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.

    Control0..1
    BindingThe codes SHALL be taken from MedicationKnowledge Status Codeshttp://hl7.org/fhir/ValueSet/medicationknowledge-status|4.0.1
    (required to http://hl7.org/fhir/ValueSet/medicationknowledge-status|4.0.1)

    A coded concept defining if the medication is in active use.

    Typecode
    Is Modifiertrue because This element changes the interpretation of all descriptive attributes.
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))

    Guidance on how to interpret the contents of this table can be foundhere

    0. MedicationKnowledge
    2. MedicationKnowledge.extension
    Control0..*
    SlicingThis element introduces a set of slices on MedicationKnowledge.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
    • value @ url
    • 4. MedicationKnowledge.extension:identifier
      Slice Nameidentifier
      Definition

      R5: MedicationKnowledge.identifier (new:Identifier)

      ShortR5: Business identifier for this medication (new)
      Comments

      Element MedicationKnowledge.identifier has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.identifier has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element). An externally-defined extension that has been mapped as the representation of FHIR R5 element MedicationKnowledge.identifier: http://hl7.org/fhir/StructureDefinition/artifact-identifier. This is a business identifier, not a resource identifier (see discussion).

      Control0..*
      TypeExtension(Artifact Identifier) (Extension Type: Identifier)
      6. MedicationKnowledge.extension:author
      Slice Nameauthor
      Definition

      R5: MedicationKnowledge.author (new:Reference(Organization))

      ShortR5: Creator or owner of the knowledge or information about the medication (new)
      Comments

      Element MedicationKnowledge.author has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.author has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element). An externally-defined extension that has been mapped as the representation of FHIR R5 element MedicationKnowledge.author: http://hl7.org/fhir/StructureDefinition/artifact-author.

      Control0..1
      TypeExtension(Artifact Author) (Extension Type: ContactDetail)
      8. MedicationKnowledge.extension:intendedJurisdiction
      Slice NameintendedJurisdiction
      Definition

      R5: MedicationKnowledge.intendedJurisdiction (new:CodeableConcept)

      ShortR5: Codes that identify the different jurisdictions for which the information of this resource was created (new)
      Comments

      Element MedicationKnowledge.intendedJurisdiction has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.intendedJurisdiction has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element). The codes could have varying granularity from a country or group of countries down to a specific district.

      Control0..*
      TypeExtension(R5: Codes that identify the different jurisdictions for which the information of this resource was created (new)) (Extension Type: CodeableConcept)
      10. MedicationKnowledge.extension:storageGuideline
      Slice NamestorageGuideline
      Definition

      R5: MedicationKnowledge.storageGuideline (new:BackboneElement)

      ShortR5: How the medication should be stored (new)
      Comments

      Element MedicationKnowledge.storageGuideline has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.storageGuideline has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

      Control0..*
      TypeExtension(R5: How the medication should be stored (new)) (Complex Extension)
      12. MedicationKnowledge.status
      14. MedicationKnowledge.status.modifierExtension
      Control0..*
      SlicingThis element introduces a set of slices on MedicationKnowledge.status.modifierExtension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
      • value @ url
      • 16. MedicationKnowledge.status.modifierExtension:status
        Slice Namestatus
        Definition

        R5: MedicationKnowledge.status

        ShortR5: active | entered-in-error | inactive
        Comments

        Element MedicationKnowledge.status is mapped to FHIR R4 element MedicationKnowledge.status as Equivalent. An externally-defined extension that has been mapped as the representation of FHIR R5 element MedicationKnowledge.status: http://hl7.org/fhir/StructureDefinition/artifact-status. This status is intended to identify if the medication in a local system is in active use within a drug database or inventory. For example, a pharmacy system may create a new drug file record for a compounded product "ABC Hospital Special Cream" with an active status. At some point in the future, it may be determined that the drug record was created with an error and the status is changed to "entered in error". This status is not intended to specify if a medication is part of a particular formulary. It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.

        Control0..1
        TypeExtension(Artifact Status) (Extension Type: code)
        18. MedicationKnowledge.synonym
        20. MedicationKnowledge.synonym.extension
        Control0..*
        SlicingThis element introduces a set of slices on MedicationKnowledge.synonym.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
        • value @ url
        • 22. MedicationKnowledge.synonym.extension:name
          Slice Namename
          Definition

          R5: MedicationKnowledge.name

          ShortR5: A name associated with the medication being described
          Comments

          Element MedicationKnowledge.name is mapped to FHIR R4 element MedicationKnowledge.synonym as Equivalent. An externally-defined extension that has been mapped as the representation of FHIR R5 element MedicationKnowledge.name: http://hl7.org/fhir/StructureDefinition/artifact-name.

          Control0..*
          TypeExtension(ArtifactName) (Extension Type: string)
          24. MedicationKnowledge.monograph
          26. MedicationKnowledge.monograph.source
          28. MedicationKnowledge.monograph.source.extension
          Control0..*
          SlicingThis element introduces a set of slices on MedicationKnowledge.monograph.source.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
          • value @ url
          • 30. MedicationKnowledge.monograph.source.extension:source
            Slice Namesource
            Definition

            R5: MedicationKnowledge.monograph.source additional types from child elements (display, identifier, reference, type)

            ShortR5: source additional types
            Comments

            Element MedicationKnowledge.monograph.source is mapped to FHIR R4 element MedicationKnowledge.monograph.source as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.monograph.source do not cover the following types based on type expansion: display, identifier, reference, type. The standard extension alternate-reference has been mapped as the representation of FHIR R5 element MedicationKnowledge.monograph.source with unmapped reference targets: DocumentReference.

            Control0..1
            TypeExtension(Alternate Reference) (Extension Type: Reference(Resource))
            32. MedicationKnowledge.ingredient
            34. MedicationKnowledge.ingredient.extension
            Control0..*
            SlicingThis element introduces a set of slices on MedicationKnowledge.ingredient.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
            • value @ url
            • 36. MedicationKnowledge.ingredient.extension:type
              Slice Nametype
              Definition

              R5: MedicationKnowledge.definitional.ingredient.type (new:CodeableConcept)

              ShortR5: A code that defines the type of ingredient, active, base, etc (new)
              Comments

              Element MedicationKnowledge.definitional.ingredient.type has a context of MedicationKnowledge.ingredient based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.definitional.ingredient.type has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

              Control0..1
              TypeExtension(R5: A code that defines the type of ingredient, active, base, etc (new)) (Extension Type: CodeableConcept)
              38. MedicationKnowledge.ingredient.strength
              40. MedicationKnowledge.ingredient.strength.extension
              Control0..*
              SlicingThis element introduces a set of slices on MedicationKnowledge.ingredient.strength.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
              • value @ url
              • 42. MedicationKnowledge.ingredient.strength.extension:strength
                Slice Namestrength
                Definition

                R5: MedicationKnowledge.definitional.ingredient.strength[x] additional types (CodeableConcept, Quantity)

                ShortR5: strength additional types
                Comments

                Element MedicationKnowledge.definitional.ingredient.strength[x] is mapped to FHIR R4 element MedicationKnowledge.ingredient.strength as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.definitional.ingredient.strength[x] do not cover the following types: CodeableConcept, Quantity.

                Control0..1
                TypeExtension(R5: strength additional types) (Extension Type: Choice of: CodeableConcept, Quantity)
                44. MedicationKnowledge.cost
                46. MedicationKnowledge.cost.extension
                Control0..*
                SlicingThis element introduces a set of slices on MedicationKnowledge.cost.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                • value @ url
                • 48. MedicationKnowledge.cost.extension:effectiveDate
                  Slice NameeffectiveDate
                  Definition

                  R5: MedicationKnowledge.cost.effectiveDate (new:Period)

                  ShortR5: The date range for which the cost is effective (new)
                  Comments

                  Element MedicationKnowledge.cost.effectiveDate has a context of MedicationKnowledge.cost based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.cost.effectiveDate has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                  Control0..*
                  TypeExtension(R5: The date range for which the cost is effective (new)) (Extension Type: Period)
                  50. MedicationKnowledge.cost.cost
                  52. MedicationKnowledge.cost.cost.extension
                  Control0..*
                  SlicingThis element introduces a set of slices on MedicationKnowledge.cost.cost.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                  • value @ url
                  • 54. MedicationKnowledge.cost.cost.extension:cost
                    Slice Namecost
                    Definition

                    R5: MedicationKnowledge.cost.cost[x] additional types (CodeableConcept) additional types from child elements (coding, text)

                    ShortR5: The price or category of the cost of the medication additional types
                    Comments

                    Element MedicationKnowledge.cost.cost[x] is mapped to FHIR R4 element MedicationKnowledge.cost.cost as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.cost.cost[x] do not cover the following types: CodeableConcept. The mappings for MedicationKnowledge.cost.cost[x] do not cover the following types based on type expansion: coding, text.

                    Control0..1
                    TypeExtension(R5: The price or category of the cost of the medication additional types) (Extension Type: CodeableConcept)
                    56. MedicationKnowledge.administrationGuidelines
                    58. MedicationKnowledge.administrationGuidelines.extension
                    Control0..*
                    SlicingThis element introduces a set of slices on MedicationKnowledge.administrationGuidelines.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                    • value @ url
                    • 60. MedicationKnowledge.administrationGuidelines.extension:dosingGuideline
                      Slice NamedosingGuideline
                      Definition

                      R5: MedicationKnowledge.indicationGuideline.dosingGuideline (new:BackboneElement)

                      ShortR5: Guidelines for dosage of the medication (new)
                      Comments

                      Element MedicationKnowledge.indicationGuideline.dosingGuideline has a context of MedicationKnowledge.administrationGuidelines based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.indicationGuideline.dosingGuideline has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                      Control0..*
                      TypeExtension(R5: Guidelines for dosage of the medication (new)) (Complex Extension)
                      62. MedicationKnowledge.medicineClassification
                      64. MedicationKnowledge.medicineClassification.extension
                      Control0..*
                      SlicingThis element introduces a set of slices on MedicationKnowledge.medicineClassification.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                      • value @ url
                      • 66. MedicationKnowledge.medicineClassification.extension:source
                        Slice Namesource
                        Definition

                        R5: MedicationKnowledge.medicineClassification.source[x] (new:string, uri)

                        ShortR5: The source of the classification (new)
                        Comments

                        Element MedicationKnowledge.medicineClassification.source[x] has a context of MedicationKnowledge.medicineClassification based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.medicineClassification.source[x] has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                        Control0..1
                        TypeExtension(R5: The source of the classification (new)) (Extension Type: Choice of: string, uri)
                        68. MedicationKnowledge.packaging
                        70. MedicationKnowledge.packaging.extension
                        Control0..*
                        SlicingThis element introduces a set of slices on MedicationKnowledge.packaging.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                        • value @ url
                        • 72. MedicationKnowledge.packaging.extension:cost
                          Slice Namecost
                          Definition

                          R5: MedicationKnowledge.packaging.cost (new:MedicationKnowledge.cost)

                          ShortR5: Cost of the packaged medication (new)
                          Comments

                          Element MedicationKnowledge.packaging.cost has a context of MedicationKnowledge.packaging based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.packaging.cost has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                          Control0..*
                          TypeExtension(R5: cost) (Complex Extension)
                          74. MedicationKnowledge.packaging.extension:packagedProduct
                          Slice NamepackagedProduct
                          Definition

                          R5: MedicationKnowledge.packaging.packagedProduct (new:Reference(PackagedProductDefinition))

                          ShortR5: The packaged medication that is being priced (new)
                          Comments

                          Element MedicationKnowledge.packaging.packagedProduct has a context of MedicationKnowledge.packaging based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.packaging.packagedProduct has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                          Control0..1
                          TypeExtension(R5: The packaged medication that is being priced (new)) (Extension Type: Reference(Cross-version Profile for R5.PackagedProductDefinition for use in FHIR R4, Basic))
                          76. MedicationKnowledge.drugCharacteristic
                          78. MedicationKnowledge.drugCharacteristic.extension
                          Control0..*
                          SlicingThis element introduces a set of slices on MedicationKnowledge.drugCharacteristic.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                          • value @ url
                          • 80. MedicationKnowledge.drugCharacteristic.extension:definition
                            Slice Namedefinition
                            Definition

                            R5: MedicationKnowledge.definitional.definition (new:Reference(MedicinalProductDefinition))

                            ShortR5: Definitional resources that provide more information about this medication (new)
                            Comments

                            Element MedicationKnowledge.definitional.definition has a context of MedicationKnowledge.drugCharacteristic based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.definitional.definition has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                            Control0..*
                            TypeExtension(R5: Definitional resources that provide more information about this medication (new)) (Extension Type: Reference(Cross-version Profile for R5.MedicinalProductDefinition for use in FHIR R4, MedicinalProduct))
                            82. MedicationKnowledge.drugCharacteristic.extension:value
                            Slice Namevalue
                            Definition

                            R5: MedicationKnowledge.definitional.drugCharacteristic.value[x] additional types (Attachment)

                            ShortR5: value additional types
                            Comments

                            Element MedicationKnowledge.definitional.drugCharacteristic.value[x] is mapped to FHIR R4 element MedicationKnowledge.drugCharacteristic.value[x] as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.definitional.drugCharacteristic.value[x] do not cover the following types: Attachment. The target context MedicationKnowledge.drugCharacteristic.value[x] is a choice-type element and cannot directly hold extensions. The context is moved up to parent element MedicationKnowledge.drugCharacteristic. The description should be provided as a CodeableConcept, SimpleQuantity or an image. The description can be a string only when these others are not available.

                            Control0..1
                            TypeExtension(R5: value additional types) (Extension Type: Attachment)
                            84. MedicationKnowledge.contraindication
                            86. MedicationKnowledge.contraindication.extension
                            Control0..*
                            SlicingThis element introduces a set of slices on MedicationKnowledge.contraindication.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                            • value @ url
                            • 88. MedicationKnowledge.contraindication.extension:clinicalUseIssue
                              Slice NameclinicalUseIssue
                              Definition

                              R5: MedicationKnowledge.clinicalUseIssue additional types from child elements (display, identifier, reference, type)

                              ShortR5: clinicalUseIssue additional types
                              Comments

                              Element MedicationKnowledge.clinicalUseIssue is mapped to FHIR R4 element MedicationKnowledge.contraindication as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.clinicalUseIssue do not cover the following types based on type expansion: display, identifier, reference, type. The standard extension alternate-reference has been mapped as the representation of FHIR R5 element MedicationKnowledge.clinicalUseIssue with unmapped reference targets: ClinicalUseDefinition.

                              Control0..*
                              TypeExtension(Alternate Reference) (Extension Type: Reference(Resource))

                              Guidance on how to interpret the contents of this table can be foundhere

                              0. MedicationKnowledge
                              Definition

                              Information about a medication that is used to support knowledge.

                              ShortDefinition of Medication Knowledge
                              Control0..*
                              Is Modifierfalse
                              Summaryfalse
                              Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
                              dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
                              dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
                              dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
                              dom-6: A resource should have narrative for robust management (text.`div`.exists())
                              2. MedicationKnowledge.id
                              Definition

                              The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.

                              ShortLogical id of this artifact
                              Comments

                              The only time that a resource does not have an id is when it is being submitted to the server using a create operation.

                              Control0..1
                              Typeid
                              Is Modifierfalse
                              Summarytrue
                              4. MedicationKnowledge.meta
                              Definition

                              The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.

                              ShortMetadata about the resource
                              Control0..1
                              TypeMeta
                              Is Modifierfalse
                              Summarytrue
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              6. MedicationKnowledge.implicitRules
                              Definition

                              A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

                              ShortA set of rules under which this content was created
                              Comments

                              Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.

                              Control0..1
                              Typeuri
                              Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation
                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                              Summarytrue
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              8. MedicationKnowledge.language
                              Definition

                              The base language in which the resource is written.

                              ShortLanguage of the resource content
                              Comments

                              Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).

                              Control0..1
                              BindingThe codes SHOULD be taken from CommonLanguages .
                              (preferred to http://hl7.org/fhir/ValueSet/languages|4.0.1)

                              A human language.

                              Additional BindingsPurpose
                              AllLanguagesMax Binding
                              Typecode
                              Is Modifierfalse
                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                              Summaryfalse
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              10. MedicationKnowledge.text
                              Definition

                              A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.

                              ShortText summary of the resource, for human interpretation
                              Comments

                              Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later.

                              Control0..1
                              TypeNarrative
                              Is Modifierfalse
                              Summaryfalse
                              Alternate Namesnarrative, html, xhtml, display
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              12. MedicationKnowledge.contained
                              Definition

                              These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.

                              ShortContained, inline Resources
                              Comments

                              This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.

                              Control0..*
                              TypeResource
                              Is Modifierfalse
                              Summaryfalse
                              Alternate Namesinline resources, anonymous resources, contained resources
                              14. MedicationKnowledge.extension
                              Definition

                              An Extension

                              ShortExtension
                              Control0..*
                              TypeExtension
                              Is Modifierfalse
                              Summaryfalse
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                              SlicingThis element introduces a set of slices on MedicationKnowledge.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                              • value @ url
                              • 16. MedicationKnowledge.extension:identifier
                                Slice Nameidentifier
                                Definition

                                R5: MedicationKnowledge.identifier (new:Identifier)

                                ShortR5: Business identifier for this medication (new)
                                Comments

                                Element MedicationKnowledge.identifier has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.identifier has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element). An externally-defined extension that has been mapped as the representation of FHIR R5 element MedicationKnowledge.identifier: http://hl7.org/fhir/StructureDefinition/artifact-identifier. This is a business identifier, not a resource identifier (see discussion).

                                Control0..*
                                TypeExtension(Artifact Identifier) (Extension Type: Identifier)
                                Is Modifierfalse
                                Summaryfalse
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                18. MedicationKnowledge.extension:author
                                Slice Nameauthor
                                Definition

                                R5: MedicationKnowledge.author (new:Reference(Organization))

                                ShortR5: Creator or owner of the knowledge or information about the medication (new)
                                Comments

                                Element MedicationKnowledge.author has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.author has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element). An externally-defined extension that has been mapped as the representation of FHIR R5 element MedicationKnowledge.author: http://hl7.org/fhir/StructureDefinition/artifact-author.

                                Control0..1
                                TypeExtension(Artifact Author) (Extension Type: ContactDetail)
                                Is Modifierfalse
                                Summaryfalse
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                20. MedicationKnowledge.extension:intendedJurisdiction
                                Slice NameintendedJurisdiction
                                Definition

                                R5: MedicationKnowledge.intendedJurisdiction (new:CodeableConcept)

                                ShortR5: Codes that identify the different jurisdictions for which the information of this resource was created (new)
                                Comments

                                Element MedicationKnowledge.intendedJurisdiction has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.intendedJurisdiction has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element). The codes could have varying granularity from a country or group of countries down to a specific district.

                                Control0..*
                                This element is affected by the following invariants: ele-1
                                TypeExtension(R5: Codes that identify the different jurisdictions for which the information of this resource was created (new)) (Extension Type: CodeableConcept)
                                Is Modifierfalse
                                Summaryfalse
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                22. MedicationKnowledge.extension:storageGuideline
                                Slice NamestorageGuideline
                                Definition

                                R5: MedicationKnowledge.storageGuideline (new:BackboneElement)

                                ShortR5: How the medication should be stored (new)
                                Comments

                                Element MedicationKnowledge.storageGuideline has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.storageGuideline has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                                Control0..*
                                This element is affected by the following invariants: ele-1
                                TypeExtension(R5: How the medication should be stored (new)) (Complex Extension)
                                Is Modifierfalse
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                24. MedicationKnowledge.modifierExtension
                                Definition

                                May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                ShortExtensions that cannot be ignored
                                Comments

                                There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                Control0..*
                                TypeExtension
                                Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
                                Summaryfalse
                                Requirements

                                Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                Alternate Namesextensions, user content
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                26. MedicationKnowledge.code
                                Definition

                                A code that specifies this medication, or a textual description if no code is available. Usage note: This could be a standard medication code such as a code from RxNorm, SNOMED CT, IDMP etc. It could also be a national or local formulary code, optionally with translations to other code systems.

                                ShortCode that identifies this medication
                                Comments

                                Depending on the context of use, the code that was actually selected by the user (prescriber, dispenser, etc.) will have the coding.userSelected set to true. As described in the coding datatype: "A coding may be marked as a "userSelected" if a user selected the particular coded value in a user interface (e.g. the user selects an item in a pick-list). If a user selected coding exists, it is the preferred choice for performing translations etc. Other codes can only be literal translations to alternative code systems, or codes at a lower level of granularity (e.g. a generic code for a vendor-specific primary one).

                                Control0..1
                                BindingFor example codes, see SNOMEDCTMedicationCodes
                                (example to http://hl7.org/fhir/ValueSet/medication-codes|4.0.1)

                                A coded concept that defines the type of a medication.

                                TypeCodeableConcept
                                Is Modifierfalse
                                Summarytrue
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                28. MedicationKnowledge.status
                                Definition

                                A code to indicate if the medication is in active use. The status refers to the validity about the information of the medication and not to its medicinal properties.

                                Shortactive | inactive | entered-in-error
                                Comments

                                This status is intended to identify if the medication in a local system is in active use within a drug database or inventory. For example, a pharmacy system may create a new drug file record for a compounded product "ABC Hospital Special Cream" with an active status. At some point in the future, it may be determined that the drug record was created with an error and the status is changed to "entered in error". This status is not intended to specify if a medication is part of a particular formulary. It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.

                                Control0..1
                                BindingThe codes SHALL be taken from MedicationKnowledge Status Codes
                                (required to http://hl7.org/fhir/ValueSet/medicationknowledge-status|4.0.1)

                                A coded concept defining if the medication is in active use.

                                Typecode
                                Is Modifiertrue because This element changes the interpretation of all descriptive attributes.
                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                Summarytrue
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                30. MedicationKnowledge.status.id
                                Definition

                                unique id for the element within a resource (for internal references)

                                Shortxml:id (or equivalent in JSON)
                                Control0..1
                                Typestring
                                Is Modifierfalse
                                XML FormatIn the XML format, this property is represented as an attribute.
                                Summaryfalse
                                32. MedicationKnowledge.status.extension
                                Definition

                                May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                ShortAdditional content defined by implementations
                                Comments

                                There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                Control0..*
                                TypeExtension
                                Is Modifierfalse
                                Summaryfalse
                                Alternate Namesextensions, user content
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                34. MedicationKnowledge.status.value
                                Definition

                                Primitive value for code

                                ShortPrimitive value for code
                                Control0..1
                                Typestring
                                Is Modifierfalse
                                XML FormatIn the XML format, this property is represented as an attribute.
                                Summaryfalse
                                36. MedicationKnowledge.manufacturer
                                Definition

                                Describes the details of the manufacturer of the medication product. This is not intended to represent the distributor of a medication product.

                                ShortManufacturer of the item
                                Control0..1
                                TypeReference(Organization)
                                Is Modifierfalse
                                Summarytrue
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                38. MedicationKnowledge.doseForm
                                Definition

                                Describes the form of the item. Powder; tablets; capsule.

                                Shortpowder | tablets | capsule +
                                Comments

                                When Medication is referenced from MedicationRequest, this is the ordered form. When Medication is referenced within MedicationDispense, this is the dispensed form. When Medication is referenced within MedicationAdministration, this is administered form.

                                Control0..1
                                BindingFor example codes, see SNOMEDCTFormCodes
                                (example to http://hl7.org/fhir/ValueSet/medication-form-codes|4.0.1)

                                A coded concept defining the form of a medication.

                                TypeCodeableConcept
                                Is Modifierfalse
                                Summaryfalse
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                40. MedicationKnowledge.amount
                                Definition

                                Specific amount of the drug in the packaged product. For example, when specifying a product that has the same strength (For example, Insulin glargine 100 unit per mL solution for injection), this attribute provides additional clarification of the package amount (For example, 3 mL, 10mL, etc.).

                                ShortAmount of drug in package
                                Comments

                                This is the quantity of medication in a package. To specify the strength of the medication, the Ingredient.strength attribute is used.

                                Control0..1
                                TypeQuantity(SimpleQuantity)
                                Is Modifierfalse
                                Summarytrue
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                42. MedicationKnowledge.synonym
                                Definition

                                Additional names for a medication, for example, the name(s) given to a medication in different countries. For example, acetaminophen and paracetamol or salbutamol and albuterol.

                                ShortAdditional names for a medication
                                Control0..*
                                Typestring
                                Is Modifierfalse
                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                Summarytrue
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                44. MedicationKnowledge.synonym.id
                                Definition

                                unique id for the element within a resource (for internal references)

                                Shortxml:id (or equivalent in JSON)
                                Control0..1
                                Typestring
                                Is Modifierfalse
                                XML FormatIn the XML format, this property is represented as an attribute.
                                Summaryfalse
                                46. MedicationKnowledge.synonym.extension
                                Definition

                                An Extension

                                ShortExtension
                                Control0..*
                                TypeExtension
                                Is Modifierfalse
                                Summaryfalse
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                SlicingThis element introduces a set of slices on MedicationKnowledge.synonym.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                • value @ url
                                • 48. MedicationKnowledge.synonym.extension:name
                                  Slice Namename
                                  Definition

                                  R5: MedicationKnowledge.name

                                  ShortR5: A name associated with the medication being described
                                  Comments

                                  Element MedicationKnowledge.name is mapped to FHIR R4 element MedicationKnowledge.synonym as Equivalent. An externally-defined extension that has been mapped as the representation of FHIR R5 element MedicationKnowledge.name: http://hl7.org/fhir/StructureDefinition/artifact-name.

                                  Control0..*
                                  TypeExtension(ArtifactName) (Extension Type: string)
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  50. MedicationKnowledge.synonym.value
                                  Definition

                                  The actual value

                                  ShortPrimitive value for string
                                  Control0..1
                                  Typestring
                                  Is Modifierfalse
                                  XML FormatIn the XML format, this property is represented as an attribute.
                                  Summaryfalse
                                  Max Length:1048576
                                  52. MedicationKnowledge.relatedMedicationKnowledge
                                  Definition

                                  Associated or related knowledge about a medication.

                                  ShortAssociated or related medication information
                                  Control0..*
                                  TypeBackboneElement
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  54. MedicationKnowledge.relatedMedicationKnowledge.id
                                  Definition

                                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                  ShortUnique id for inter-element referencing
                                  Control0..1
                                  Typestring
                                  Is Modifierfalse
                                  XML FormatIn the XML format, this property is represented as an attribute.
                                  Summaryfalse
                                  56. MedicationKnowledge.relatedMedicationKnowledge.extension
                                  Definition

                                  May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                  ShortAdditional content defined by implementations
                                  Comments

                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                  Control0..*
                                  TypeExtension
                                  Is Modifierfalse
                                  Summaryfalse
                                  Alternate Namesextensions, user content
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  58. MedicationKnowledge.relatedMedicationKnowledge.modifierExtension
                                  Definition

                                  May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                  ShortExtensions that cannot be ignored even if unrecognized
                                  Comments

                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                  Control0..*
                                  TypeExtension
                                  Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                  Summarytrue
                                  Requirements

                                  Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                  Alternate Namesextensions, user content, modifiers
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  60. MedicationKnowledge.relatedMedicationKnowledge.type
                                  Definition

                                  The category of the associated medication knowledge reference.

                                  ShortCategory of medicationKnowledge
                                  Control1..1
                                  TypeCodeableConcept
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  62. MedicationKnowledge.relatedMedicationKnowledge.reference
                                  Definition

                                  Associated documentation about the associated medication knowledge.

                                  ShortAssociated documentation about the associated medication knowledge
                                  Control1..*
                                  TypeReference(MedicationKnowledge)
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  64. MedicationKnowledge.associatedMedication
                                  Definition

                                  Associated or related medications. For example, if the medication is a branded product (e.g. Crestor), this is the Therapeutic Moeity (e.g. Rosuvastatin) or if this is a generic medication (e.g. Rosuvastatin), this would link to a branded product (e.g. Crestor).

                                  ShortA medication resource that is associated with this medication
                                  Control0..*
                                  TypeReference(Medication)
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  66. MedicationKnowledge.productType
                                  Definition

                                  Category of the medication or product (e.g. branded product, therapeutic moeity, generic product, innovator product, etc.).

                                  ShortCategory of the medication or product
                                  Control0..*
                                  TypeCodeableConcept
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  68. MedicationKnowledge.monograph
                                  Definition

                                  Associated documentation about the medication.

                                  ShortAssociated documentation about the medication
                                  Control0..*
                                  TypeBackboneElement
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  70. MedicationKnowledge.monograph.id
                                  Definition

                                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                  ShortUnique id for inter-element referencing
                                  Control0..1
                                  Typestring
                                  Is Modifierfalse
                                  XML FormatIn the XML format, this property is represented as an attribute.
                                  Summaryfalse
                                  72. MedicationKnowledge.monograph.extension
                                  Definition

                                  May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                  ShortAdditional content defined by implementations
                                  Comments

                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                  Control0..*
                                  TypeExtension
                                  Is Modifierfalse
                                  Summaryfalse
                                  Alternate Namesextensions, user content
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  74. MedicationKnowledge.monograph.modifierExtension
                                  Definition

                                  May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                  ShortExtensions that cannot be ignored even if unrecognized
                                  Comments

                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                  Control0..*
                                  TypeExtension
                                  Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                  Summarytrue
                                  Requirements

                                  Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                  Alternate Namesextensions, user content, modifiers
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  76. MedicationKnowledge.monograph.type
                                  Definition

                                  The category of documentation about the medication. (e.g. professional monograph, patient education monograph).

                                  ShortThe category of medication document
                                  Control0..1
                                  TypeCodeableConcept
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  78. MedicationKnowledge.monograph.source
                                  Definition

                                  Associated documentation about the medication.

                                  ShortAssociated documentation about the medication
                                  Control0..1
                                  TypeReference(DocumentReference, Media)
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  80. MedicationKnowledge.monograph.source.id
                                  Definition

                                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                  ShortUnique id for inter-element referencing
                                  Control0..1
                                  Typestring
                                  Is Modifierfalse
                                  XML FormatIn the XML format, this property is represented as an attribute.
                                  Summaryfalse
                                  82. MedicationKnowledge.monograph.source.extension
                                  Definition

                                  An Extension

                                  ShortExtension
                                  Control0..*
                                  TypeExtension
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  SlicingThis element introduces a set of slices on MedicationKnowledge.monograph.source.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                  • value @ url
                                  • 84. MedicationKnowledge.monograph.source.extension:source
                                    Slice Namesource
                                    Definition

                                    R5: MedicationKnowledge.monograph.source additional types from child elements (display, identifier, reference, type)

                                    ShortR5: source additional types
                                    Comments

                                    Element MedicationKnowledge.monograph.source is mapped to FHIR R4 element MedicationKnowledge.monograph.source as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.monograph.source do not cover the following types based on type expansion: display, identifier, reference, type. The standard extension alternate-reference has been mapped as the representation of FHIR R5 element MedicationKnowledge.monograph.source with unmapped reference targets: DocumentReference.

                                    Control0..1
                                    TypeExtension(Alternate Reference) (Extension Type: Reference(Resource))
                                    Is Modifierfalse
                                    Summaryfalse
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                    86. MedicationKnowledge.monograph.source.reference
                                    Definition

                                    A reference to a location at which the other resource is found. The reference may be a relative reference, in which case it is relative to the service base URL, or an absolute URL that resolves to the location where the resource is found. The reference may be version specific or not. If the reference is not to a FHIR RESTful server, then it should be assumed to be version specific. Internal fragment references (start with '#') refer to contained resources.

                                    ShortLiteral reference, Relative, internal or absolute URL
                                    Comments

                                    Using absolute URLs provides a stable scalable approach suitable for a cloud/web context, while using relative/logical references provides a flexible approach suitable for use when trading across closed eco-system boundaries. Absolute URLs do not need to point to a FHIR RESTful server, though this is the preferred approach. If the URL conforms to the structure "/[type]/[id]" then it should be assumed that the reference is to a FHIR RESTful server.

                                    Control0..1
                                    This element is affected by the following invariants: ref-1
                                    Typestring
                                    Is Modifierfalse
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    88. MedicationKnowledge.monograph.source.type
                                    Definition

                                    The expected type of the target of the reference. If both Reference.type and Reference.reference are populated and Reference.reference is a FHIR URL, both SHALL be consistent.

                                    The type is the Canonical URL of Resource Definition that is the type this reference refers to. References are URLs that are relative to http://hl7.org/fhir/StructureDefinition/ e.g. "Patient" is a reference to http://hl7.org/fhir/StructureDefinition/Patient. Absolute URLs are only allowed for logical models (and can only be used in references in logical models, not resources).

                                    ShortType the reference refers to (e.g. "Patient")
                                    Comments

                                    This element is used to indicate the type of the target of the reference. This may be used which ever of the other elements are populated (or not). In some cases, the type of the target may be determined by inspection of the reference (e.g. a RESTful URL) or by resolving the target of the reference; if both the type and a reference is provided, the reference SHALL resolve to a resource of the same type as that specified.

                                    Control0..1
                                    BindingUnless not suitable, these codes SHALL be taken from ResourceType .
                                    (extensible to http://hl7.org/fhir/ValueSet/resource-types|4.0.1)

                                    Aa resource (or, for logical models, the URI of the logical model).

                                    Typeuri
                                    Is Modifierfalse
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    90. MedicationKnowledge.monograph.source.identifier
                                    Definition

                                    An identifier for the target resource. This is used when there is no way to reference the other resource directly, either because the entity it represents is not available through a FHIR server, or because there is no way for the author of the resource to convert a known identifier to an actual location. There is no requirement that a Reference.identifier point to something that is actually exposed as a FHIR instance, but it SHALL point to a business concept that would be expected to be exposed as a FHIR instance, and that instance would need to be of a FHIR resource type allowed by the reference.

                                    ShortLogical reference, when literal reference is not known
                                    Comments

                                    When an identifier is provided in place of a reference, any system processing the reference will only be able to resolve the identifier to a reference if it understands the business context in which the identifier is used. Sometimes this is global (e.g. a national identifier) but often it is not. For this reason, none of the useful mechanisms described for working with references (e.g. chaining, includes) are possible, nor should servers be expected to be able resolve the reference. Servers may accept an identifier based reference untouched, resolve it, and/or reject it - see CapabilityStatement.rest.resource.referencePolicy.

                                    When both an identifier and a literal reference are provided, the literal reference is preferred. Applications processing the resource are allowed - but not required - to check that the identifier matches the literal reference

                                    Applications converting a logical reference to a literal reference may choose to leave the logical reference present, or remove it.

                                    Reference is intended to point to a structure that can potentially be expressed as a FHIR resource, though there is no need for it to exist as an actual FHIR resource instance - except in as much as an application wishes to actual find the target of the reference. The content referred to be the identifier must meet the logical constraints implied by any limitations on what resource types are permitted for the reference. For example, it would not be legitimate to send the identifier for a drug prescription if the type were Reference(Observation|DiagnosticReport). One of the use-cases for Reference.identifier is the situation where no FHIR representation exists (where the type is Reference (Any).

                                    NoteThis is a business identifier, not a resource identifier (see discussion)
                                    Control0..1
                                    TypeIdentifier
                                    Is Modifierfalse
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    92. MedicationKnowledge.monograph.source.display
                                    Definition

                                    Plain text narrative that identifies the resource in addition to the resource reference.

                                    ShortText alternative for the resource
                                    Comments

                                    This is generally not the same as the Resource.text of the referenced resource. The purpose is to identify what's being referenced, not to fully describe it.

                                    Control0..1
                                    Typestring
                                    Is Modifierfalse
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    94. MedicationKnowledge.ingredient
                                    Definition

                                    Identifies a particular constituent of interest in the product.

                                    ShortActive or inactive ingredient
                                    Control0..*
                                    TypeBackboneElement
                                    Is Modifierfalse
                                    Summaryfalse
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    96. MedicationKnowledge.ingredient.id
                                    Definition

                                    Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                    ShortUnique id for inter-element referencing
                                    Control0..1
                                    Typestring
                                    Is Modifierfalse
                                    XML FormatIn the XML format, this property is represented as an attribute.
                                    Summaryfalse
                                    98. MedicationKnowledge.ingredient.extension
                                    Definition

                                    An Extension

                                    ShortExtension
                                    Control0..*
                                    TypeExtension
                                    Is Modifierfalse
                                    Summaryfalse
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                    SlicingThis element introduces a set of slices on MedicationKnowledge.ingredient.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                    • value @ url
                                    • 100. MedicationKnowledge.ingredient.extension:type
                                      Slice Nametype
                                      Definition

                                      R5: MedicationKnowledge.definitional.ingredient.type (new:CodeableConcept)

                                      ShortR5: A code that defines the type of ingredient, active, base, etc (new)
                                      Comments

                                      Element MedicationKnowledge.definitional.ingredient.type has a context of MedicationKnowledge.ingredient based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.definitional.ingredient.type has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                                      Control0..1
                                      This element is affected by the following invariants: ele-1
                                      TypeExtension(R5: A code that defines the type of ingredient, active, base, etc (new)) (Extension Type: CodeableConcept)
                                      Is Modifierfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                      102. MedicationKnowledge.ingredient.modifierExtension
                                      Definition

                                      May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                      Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                      ShortExtensions that cannot be ignored even if unrecognized
                                      Comments

                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                      Control0..*
                                      TypeExtension
                                      Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                      Summarytrue
                                      Requirements

                                      Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                      Alternate Namesextensions, user content, modifiers
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                      104. MedicationKnowledge.ingredient.item[x]
                                      Definition

                                      The actual ingredient - either a substance (simple ingredient) or another medication.

                                      ShortMedication(s) or substance(s) contained in the medication
                                      Control1..1
                                      TypeChoice of: CodeableConcept, Reference(Substance)
                                      [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                      Is Modifierfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      106. MedicationKnowledge.ingredient.isActive
                                      Definition

                                      Indication of whether this ingredient affects the therapeutic action of the drug.

                                      ShortActive ingredient indicator
                                      Control0..1
                                      Typeboolean
                                      Is Modifierfalse
                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                      Summaryfalse
                                      Requirements

                                      True indicates that the ingredient affects the therapeutic action of the drug (i.e. active). False indicates that the ingredient does not affect the therapeutic action of the drug (i.e. inactive).

                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      108. MedicationKnowledge.ingredient.strength
                                      Definition

                                      Specifies how many (or how much) of the items there are in this Medication. For example, 250 mg per tablet. This is expressed as a ratio where the numerator is 250mg and the denominator is 1 tablet.

                                      ShortQuantity of ingredient present
                                      Control0..1
                                      TypeRatio
                                      Is Modifierfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      110. MedicationKnowledge.ingredient.strength.id
                                      Definition

                                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                      ShortUnique id for inter-element referencing
                                      Control0..1
                                      Typestring
                                      Is Modifierfalse
                                      XML FormatIn the XML format, this property is represented as an attribute.
                                      Summaryfalse
                                      112. MedicationKnowledge.ingredient.strength.extension
                                      Definition

                                      An Extension

                                      ShortExtension
                                      Control0..*
                                      TypeExtension
                                      Is Modifierfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                      SlicingThis element introduces a set of slices on MedicationKnowledge.ingredient.strength.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                      • value @ url
                                      • 114. MedicationKnowledge.ingredient.strength.extension:strength
                                        Slice Namestrength
                                        Definition

                                        R5: MedicationKnowledge.definitional.ingredient.strength[x] additional types (CodeableConcept, Quantity)

                                        ShortR5: strength additional types
                                        Comments

                                        Element MedicationKnowledge.definitional.ingredient.strength[x] is mapped to FHIR R4 element MedicationKnowledge.ingredient.strength as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.definitional.ingredient.strength[x] do not cover the following types: CodeableConcept, Quantity.

                                        Control0..1
                                        TypeExtension(R5: strength additional types) (Extension Type: Choice of: CodeableConcept, Quantity)
                                        Is Modifierfalse
                                        Summaryfalse
                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                        116. MedicationKnowledge.ingredient.strength.numerator
                                        Definition

                                        The value of the numerator.

                                        ShortNumerator value
                                        Control0..1
                                        TypeQuantity
                                        Is Modifierfalse
                                        Summarytrue
                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                        118. MedicationKnowledge.ingredient.strength.denominator
                                        Definition

                                        The value of the denominator.

                                        ShortDenominator value
                                        Control0..1
                                        TypeQuantity
                                        Is Modifierfalse
                                        Summarytrue
                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                        120. MedicationKnowledge.preparationInstruction
                                        Definition

                                        The instructions for preparing the medication.

                                        ShortThe instructions for preparing the medication
                                        Control0..1
                                        Typemarkdown
                                        Is Modifierfalse
                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                        Summaryfalse
                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                        122. MedicationKnowledge.intendedRoute
                                        Definition

                                        The intended or approved route of administration.

                                        ShortThe intended or approved route of administration
                                        Control0..*
                                        BindingFor example codes, see SNOMEDCTRouteCodes
                                        (example to http://hl7.org/fhir/ValueSet/route-codes|4.0.1)

                                        A coded concept defining the intended route of administration.

                                        TypeCodeableConcept
                                        Is Modifierfalse
                                        Summaryfalse
                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                        124. MedicationKnowledge.cost
                                        Definition

                                        The price of the medication.

                                        ShortThe pricing of the medication
                                        Control0..*
                                        TypeBackboneElement
                                        Is Modifierfalse
                                        Summaryfalse
                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                        126. MedicationKnowledge.cost.id
                                        Definition

                                        Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                        ShortUnique id for inter-element referencing
                                        Control0..1
                                        Typestring
                                        Is Modifierfalse
                                        XML FormatIn the XML format, this property is represented as an attribute.
                                        Summaryfalse
                                        128. MedicationKnowledge.cost.extension
                                        Definition

                                        An Extension

                                        ShortExtension
                                        Control0..*
                                        TypeExtension
                                        Is Modifierfalse
                                        Summaryfalse
                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                        SlicingThis element introduces a set of slices on MedicationKnowledge.cost.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                        • value @ url
                                        • 130. MedicationKnowledge.cost.extension:effectiveDate
                                          Slice NameeffectiveDate
                                          Definition

                                          R5: MedicationKnowledge.cost.effectiveDate (new:Period)

                                          ShortR5: The date range for which the cost is effective (new)
                                          Comments

                                          Element MedicationKnowledge.cost.effectiveDate has a context of MedicationKnowledge.cost based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.cost.effectiveDate has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                                          Control0..*
                                          This element is affected by the following invariants: ele-1
                                          TypeExtension(R5: The date range for which the cost is effective (new)) (Extension Type: Period)
                                          Is Modifierfalse
                                          Summaryfalse
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                          132. MedicationKnowledge.cost.modifierExtension
                                          Definition

                                          May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                          Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                          ShortExtensions that cannot be ignored even if unrecognized
                                          Comments

                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                          Control0..*
                                          TypeExtension
                                          Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                          Summarytrue
                                          Requirements

                                          Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                          Alternate Namesextensions, user content, modifiers
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                          134. MedicationKnowledge.cost.type
                                          Definition

                                          The category of the cost information. For example, manufacturers' cost, patient cost, claim reimbursement cost, actual acquisition cost.

                                          ShortThe category of the cost information
                                          Control1..1
                                          TypeCodeableConcept
                                          Is Modifierfalse
                                          Summaryfalse
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          136. MedicationKnowledge.cost.source
                                          Definition

                                          The source or owner that assigns the price to the medication.

                                          ShortThe source or owner for the price information
                                          Control0..1
                                          Typestring
                                          Is Modifierfalse
                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                          Summaryfalse
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          138. MedicationKnowledge.cost.cost
                                          Definition

                                          The price of the medication.

                                          ShortThe price of the medication
                                          Control1..1
                                          TypeMoney
                                          Is Modifierfalse
                                          Summaryfalse
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          140. MedicationKnowledge.cost.cost.id
                                          Definition

                                          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                          ShortUnique id for inter-element referencing
                                          Control0..1
                                          Typestring
                                          Is Modifierfalse
                                          XML FormatIn the XML format, this property is represented as an attribute.
                                          Summaryfalse
                                          142. MedicationKnowledge.cost.cost.extension
                                          Definition

                                          An Extension

                                          ShortExtension
                                          Control0..*
                                          TypeExtension
                                          Is Modifierfalse
                                          Summaryfalse
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                          SlicingThis element introduces a set of slices on MedicationKnowledge.cost.cost.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                          • value @ url
                                          • 144. MedicationKnowledge.cost.cost.extension:cost
                                            Slice Namecost
                                            Definition

                                            R5: MedicationKnowledge.cost.cost[x] additional types (CodeableConcept) additional types from child elements (coding, text)

                                            ShortR5: The price or category of the cost of the medication additional types
                                            Comments

                                            Element MedicationKnowledge.cost.cost[x] is mapped to FHIR R4 element MedicationKnowledge.cost.cost as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.cost.cost[x] do not cover the following types: CodeableConcept. The mappings for MedicationKnowledge.cost.cost[x] do not cover the following types based on type expansion: coding, text.

                                            Control1..1
                                            TypeExtension(R5: The price or category of the cost of the medication additional types) (Extension Type: CodeableConcept)
                                            Is Modifierfalse
                                            Summaryfalse
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                            146. MedicationKnowledge.cost.cost.value
                                            Definition

                                            Numerical value (with implicit precision).

                                            ShortNumerical value (with implicit precision)
                                            Comments

                                            Monetary values have their own rules for handling precision (refer to standard accounting text books).

                                            Control0..1
                                            Typedecimal
                                            Is Modifierfalse
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summarytrue
                                            Requirements

                                            The amount of the currency. The value includes an implicit precision in the presentation of the value.

                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            148. MedicationKnowledge.cost.cost.currency
                                            Definition

                                            ISO 4217 Currency Code.

                                            ShortISO 4217 Currency Code
                                            Control0..1
                                            BindingThe codes SHALL be taken from Currencies
                                            (required to http://hl7.org/fhir/ValueSet/currencies|4.0.1)

                                            A code indicating the currency, taken from ISO 4217.

                                            Typecode
                                            Is Modifierfalse
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summarytrue
                                            Requirements

                                            A code indicating the currency, taken from ISO 4217.

                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            150. MedicationKnowledge.monitoringProgram
                                            Definition

                                            The program under which the medication is reviewed.

                                            ShortProgram under which a medication is reviewed
                                            Control0..*
                                            TypeBackboneElement
                                            Is Modifierfalse
                                            Summaryfalse
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            152. MedicationKnowledge.monitoringProgram.id
                                            Definition

                                            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                            ShortUnique id for inter-element referencing
                                            Control0..1
                                            Typestring
                                            Is Modifierfalse
                                            XML FormatIn the XML format, this property is represented as an attribute.
                                            Summaryfalse
                                            154. MedicationKnowledge.monitoringProgram.extension
                                            Definition

                                            May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                            ShortAdditional content defined by implementations
                                            Comments

                                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                            Control0..*
                                            TypeExtension
                                            Is Modifierfalse
                                            Summaryfalse
                                            Alternate Namesextensions, user content
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                            156. MedicationKnowledge.monitoringProgram.modifierExtension
                                            Definition

                                            May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                            Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                            ShortExtensions that cannot be ignored even if unrecognized
                                            Comments

                                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                            Control0..*
                                            TypeExtension
                                            Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                            Summarytrue
                                            Requirements

                                            Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                            Alternate Namesextensions, user content, modifiers
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                            158. MedicationKnowledge.monitoringProgram.type
                                            Definition

                                            Type of program under which the medication is monitored.

                                            ShortType of program under which the medication is monitored
                                            Control0..1
                                            TypeCodeableConcept
                                            Is Modifierfalse
                                            Summaryfalse
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            160. MedicationKnowledge.monitoringProgram.name
                                            Definition

                                            Name of the reviewing program.

                                            ShortName of the reviewing program
                                            Control0..1
                                            Typestring
                                            Is Modifierfalse
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summaryfalse
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            162. MedicationKnowledge.administrationGuidelines
                                            Definition

                                            Guidelines for the administration of the medication.

                                            ShortGuidelines for administration of the medication
                                            Control0..*
                                            TypeBackboneElement
                                            Is Modifierfalse
                                            Summaryfalse
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            164. MedicationKnowledge.administrationGuidelines.id
                                            Definition

                                            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                            ShortUnique id for inter-element referencing
                                            Control0..1
                                            Typestring
                                            Is Modifierfalse
                                            XML FormatIn the XML format, this property is represented as an attribute.
                                            Summaryfalse
                                            166. MedicationKnowledge.administrationGuidelines.extension
                                            Definition

                                            An Extension

                                            ShortExtension
                                            Control0..*
                                            TypeExtension
                                            Is Modifierfalse
                                            Summaryfalse
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                            SlicingThis element introduces a set of slices on MedicationKnowledge.administrationGuidelines.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                            • value @ url
                                            • 168. MedicationKnowledge.administrationGuidelines.extension:dosingGuideline
                                              Slice NamedosingGuideline
                                              Definition

                                              R5: MedicationKnowledge.indicationGuideline.dosingGuideline (new:BackboneElement)

                                              ShortR5: Guidelines for dosage of the medication (new)
                                              Comments

                                              Element MedicationKnowledge.indicationGuideline.dosingGuideline has a context of MedicationKnowledge.administrationGuidelines based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.indicationGuideline.dosingGuideline has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                                              Control0..*
                                              This element is affected by the following invariants: ele-1
                                              TypeExtension(R5: Guidelines for dosage of the medication (new)) (Complex Extension)
                                              Is Modifierfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                              170. MedicationKnowledge.administrationGuidelines.modifierExtension
                                              Definition

                                              May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                              Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                              ShortExtensions that cannot be ignored even if unrecognized
                                              Comments

                                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                              Control0..*
                                              TypeExtension
                                              Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                              Summarytrue
                                              Requirements

                                              Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                              Alternate Namesextensions, user content, modifiers
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                              172. MedicationKnowledge.administrationGuidelines.dosage
                                              Definition

                                              Dosage for the medication for the specific guidelines.

                                              ShortDosage for the medication for the specific guidelines
                                              Control0..*
                                              TypeBackboneElement
                                              Is Modifierfalse
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              174. MedicationKnowledge.administrationGuidelines.dosage.id
                                              Definition

                                              Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                              ShortUnique id for inter-element referencing
                                              Control0..1
                                              Typestring
                                              Is Modifierfalse
                                              XML FormatIn the XML format, this property is represented as an attribute.
                                              Summaryfalse
                                              176. MedicationKnowledge.administrationGuidelines.dosage.extension
                                              Definition

                                              May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                              ShortAdditional content defined by implementations
                                              Comments

                                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                              Control0..*
                                              TypeExtension
                                              Is Modifierfalse
                                              Summaryfalse
                                              Alternate Namesextensions, user content
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                              178. MedicationKnowledge.administrationGuidelines.dosage.modifierExtension
                                              Definition

                                              May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                              Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                              ShortExtensions that cannot be ignored even if unrecognized
                                              Comments

                                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                              Control0..*
                                              TypeExtension
                                              Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                              Summarytrue
                                              Requirements

                                              Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                              Alternate Namesextensions, user content, modifiers
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                              180. MedicationKnowledge.administrationGuidelines.dosage.type
                                              Definition

                                              The type of dosage (for example, prophylaxis, maintenance, therapeutic, etc.).

                                              ShortType of dosage
                                              Control1..1
                                              TypeCodeableConcept
                                              Is Modifierfalse
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              182. MedicationKnowledge.administrationGuidelines.dosage.dosage
                                              Definition

                                              Dosage for the medication for the specific guidelines.

                                              ShortDosage for the medication for the specific guidelines
                                              Control1..*
                                              TypeDosage
                                              Is Modifierfalse
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              184. MedicationKnowledge.administrationGuidelines.indication[x]
                                              Definition

                                              Indication for use that apply to the specific administration guidelines.

                                              ShortIndication for use that apply to the specific administration guidelines
                                              Control0..1
                                              TypeChoice of: CodeableConcept, Reference(ObservationDefinition)
                                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                              Is Modifierfalse
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              186. MedicationKnowledge.administrationGuidelines.patientCharacteristics
                                              Definition

                                              Characteristics of the patient that are relevant to the administration guidelines (for example, height, weight, gender, etc.).

                                              ShortCharacteristics of the patient that are relevant to the administration guidelines
                                              Control0..*
                                              TypeBackboneElement
                                              Is Modifierfalse
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              188. MedicationKnowledge.administrationGuidelines.patientCharacteristics.id
                                              Definition

                                              Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                              ShortUnique id for inter-element referencing
                                              Control0..1
                                              Typestring
                                              Is Modifierfalse
                                              XML FormatIn the XML format, this property is represented as an attribute.
                                              Summaryfalse
                                              190. MedicationKnowledge.administrationGuidelines.patientCharacteristics.extension
                                              Definition

                                              May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                              ShortAdditional content defined by implementations
                                              Comments

                                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                              Control0..*
                                              TypeExtension
                                              Is Modifierfalse
                                              Summaryfalse
                                              Alternate Namesextensions, user content
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                              192. MedicationKnowledge.administrationGuidelines.patientCharacteristics.modifierExtension
                                              Definition

                                              May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                              Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                              ShortExtensions that cannot be ignored even if unrecognized
                                              Comments

                                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                              Control0..*
                                              TypeExtension
                                              Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                              Summarytrue
                                              Requirements

                                              Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                              Alternate Namesextensions, user content, modifiers
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                              194. MedicationKnowledge.administrationGuidelines.patientCharacteristics.characteristic[x]
                                              Definition

                                              Specific characteristic that is relevant to the administration guideline (e.g. height, weight, gender).

                                              ShortSpecific characteristic that is relevant to the administration guideline
                                              Control1..1
                                              TypeChoice of: CodeableConcept, Quantity(SimpleQuantity)
                                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                              Is Modifierfalse
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              196. MedicationKnowledge.administrationGuidelines.patientCharacteristics.value
                                              Definition

                                              The specific characteristic (e.g. height, weight, gender, etc.).

                                              ShortThe specific characteristic
                                              Control0..*
                                              Typestring
                                              Is Modifierfalse
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              198. MedicationKnowledge.medicineClassification
                                              Definition

                                              Categorization of the medication within a formulary or classification system.

                                              ShortCategorization of the medication within a formulary or classification system
                                              Control0..*
                                              TypeBackboneElement
                                              Is Modifierfalse
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              200. MedicationKnowledge.medicineClassification.id
                                              Definition

                                              Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                              ShortUnique id for inter-element referencing
                                              Control0..1
                                              Typestring
                                              Is Modifierfalse
                                              XML FormatIn the XML format, this property is represented as an attribute.
                                              Summaryfalse
                                              202. MedicationKnowledge.medicineClassification.extension
                                              Definition

                                              An Extension

                                              ShortExtension
                                              Control0..*
                                              TypeExtension
                                              Is Modifierfalse
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                              SlicingThis element introduces a set of slices on MedicationKnowledge.medicineClassification.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                              • value @ url
                                              • 204. MedicationKnowledge.medicineClassification.extension:source
                                                Slice Namesource
                                                Definition

                                                R5: MedicationKnowledge.medicineClassification.source[x] (new:string, uri)

                                                ShortR5: The source of the classification (new)
                                                Comments

                                                Element MedicationKnowledge.medicineClassification.source[x] has a context of MedicationKnowledge.medicineClassification based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.medicineClassification.source[x] has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                                                Control0..1
                                                This element is affected by the following invariants: ele-1
                                                TypeExtension(R5: The source of the classification (new)) (Extension Type: Choice of: string, uri)
                                                Is Modifierfalse
                                                Summaryfalse
                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                206. MedicationKnowledge.medicineClassification.modifierExtension
                                                Definition

                                                May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                ShortExtensions that cannot be ignored even if unrecognized
                                                Comments

                                                There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                Control0..*
                                                TypeExtension
                                                Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                Summarytrue
                                                Requirements

                                                Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                Alternate Namesextensions, user content, modifiers
                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                208. MedicationKnowledge.medicineClassification.type
                                                Definition

                                                The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification).

                                                ShortThe type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
                                                Control1..1
                                                TypeCodeableConcept
                                                Is Modifierfalse
                                                Summaryfalse
                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                210. MedicationKnowledge.medicineClassification.classification
                                                Definition

                                                Specific category assigned to the medication (e.g. anti-infective, anti-hypertensive, antibiotic, etc.).

                                                ShortSpecific category assigned to the medication
                                                Control0..*
                                                TypeCodeableConcept
                                                Is Modifierfalse
                                                Summaryfalse
                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                212. MedicationKnowledge.packaging
                                                Definition

                                                Information that only applies to packages (not products).

                                                ShortDetails about packaged medications
                                                Control0..1
                                                TypeBackboneElement
                                                Is Modifierfalse
                                                Summaryfalse
                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                214. MedicationKnowledge.packaging.id
                                                Definition

                                                Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                ShortUnique id for inter-element referencing
                                                Control0..1
                                                Typestring
                                                Is Modifierfalse
                                                XML FormatIn the XML format, this property is represented as an attribute.
                                                Summaryfalse
                                                216. MedicationKnowledge.packaging.extension
                                                Definition

                                                An Extension

                                                ShortExtension
                                                Control0..*
                                                TypeExtension
                                                Is Modifierfalse
                                                Summaryfalse
                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                SlicingThis element introduces a set of slices on MedicationKnowledge.packaging.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                • value @ url
                                                • 218. MedicationKnowledge.packaging.extension:cost
                                                  Slice Namecost
                                                  Definition

                                                  R5: MedicationKnowledge.packaging.cost (new:MedicationKnowledge.cost)

                                                  ShortR5: Cost of the packaged medication (new)
                                                  Comments

                                                  Element MedicationKnowledge.packaging.cost has a context of MedicationKnowledge.packaging based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.packaging.cost has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                                                  Control0..*
                                                  This element is affected by the following invariants: ele-1
                                                  TypeExtension(R5: cost) (Complex Extension)
                                                  Is Modifierfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                  220. MedicationKnowledge.packaging.extension:packagedProduct
                                                  Slice NamepackagedProduct
                                                  Definition

                                                  R5: MedicationKnowledge.packaging.packagedProduct (new:Reference(PackagedProductDefinition))

                                                  ShortR5: The packaged medication that is being priced (new)
                                                  Comments

                                                  Element MedicationKnowledge.packaging.packagedProduct has a context of MedicationKnowledge.packaging based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.packaging.packagedProduct has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                                                  Control0..1
                                                  This element is affected by the following invariants: ele-1
                                                  TypeExtension(R5: The packaged medication that is being priced (new)) (Extension Type: Reference(Cross-version Profile for R5.PackagedProductDefinition for use in FHIR R4, Basic))
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                  222. MedicationKnowledge.packaging.modifierExtension
                                                  Definition

                                                  May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                  ShortExtensions that cannot be ignored even if unrecognized
                                                  Comments

                                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                  Control0..*
                                                  TypeExtension
                                                  Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                  Summarytrue
                                                  Requirements

                                                  Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                  Alternate Namesextensions, user content, modifiers
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                  224. MedicationKnowledge.packaging.type
                                                  Definition

                                                  A code that defines the specific type of packaging that the medication can be found in (e.g. blister sleeve, tube, bottle).

                                                  ShortA code that defines the specific type of packaging that the medication can be found in
                                                  Control0..1
                                                  BindingFor example codes, see medicationKnowledge Package Type Codes
                                                  (example to http://hl7.org/fhir/ValueSet/medicationknowledge-package-type|4.0.1)

                                                  A coded concept defining the type of packaging of a medication.

                                                  TypeCodeableConcept
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  226. MedicationKnowledge.packaging.quantity
                                                  Definition

                                                  The number of product units the package would contain if fully loaded.

                                                  ShortThe number of product units the package would contain if fully loaded
                                                  Control0..1
                                                  TypeQuantity(SimpleQuantity)
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  228. MedicationKnowledge.drugCharacteristic
                                                  Definition

                                                  Specifies descriptive properties of the medicine, such as color, shape, imprints, etc.

                                                  ShortSpecifies descriptive properties of the medicine
                                                  Control0..*
                                                  TypeBackboneElement
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  230. MedicationKnowledge.drugCharacteristic.id
                                                  Definition

                                                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                  ShortUnique id for inter-element referencing
                                                  Control0..1
                                                  Typestring
                                                  Is Modifierfalse
                                                  XML FormatIn the XML format, this property is represented as an attribute.
                                                  Summaryfalse
                                                  232. MedicationKnowledge.drugCharacteristic.extension
                                                  Definition

                                                  An Extension

                                                  ShortExtension
                                                  Control0..*
                                                  TypeExtension
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                  SlicingThis element introduces a set of slices on MedicationKnowledge.drugCharacteristic.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                  • value @ url
                                                  • 234. MedicationKnowledge.drugCharacteristic.extension:definition
                                                    Slice Namedefinition
                                                    Definition

                                                    R5: MedicationKnowledge.definitional.definition (new:Reference(MedicinalProductDefinition))

                                                    ShortR5: Definitional resources that provide more information about this medication (new)
                                                    Comments

                                                    Element MedicationKnowledge.definitional.definition has a context of MedicationKnowledge.drugCharacteristic based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.definitional.definition has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).

                                                    Control0..*
                                                    This element is affected by the following invariants: ele-1
                                                    TypeExtension(R5: Definitional resources that provide more information about this medication (new)) (Extension Type: Reference(Cross-version Profile for R5.MedicinalProductDefinition for use in FHIR R4, MedicinalProduct))
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                    236. MedicationKnowledge.drugCharacteristic.extension:value
                                                    Slice Namevalue
                                                    Definition

                                                    R5: MedicationKnowledge.definitional.drugCharacteristic.value[x] additional types (Attachment)

                                                    ShortR5: value additional types
                                                    Comments

                                                    Element MedicationKnowledge.definitional.drugCharacteristic.value[x] is mapped to FHIR R4 element MedicationKnowledge.drugCharacteristic.value[x] as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.definitional.drugCharacteristic.value[x] do not cover the following types: Attachment. The target context MedicationKnowledge.drugCharacteristic.value[x] is a choice-type element and cannot directly hold extensions. The context is moved up to parent element MedicationKnowledge.drugCharacteristic. The description should be provided as a CodeableConcept, SimpleQuantity or an image. The description can be a string only when these others are not available.

                                                    Control0..1
                                                    This element is affected by the following invariants: ele-1
                                                    TypeExtension(R5: value additional types) (Extension Type: Attachment)
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                    238. MedicationKnowledge.drugCharacteristic.modifierExtension
                                                    Definition

                                                    May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                    Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                    ShortExtensions that cannot be ignored even if unrecognized
                                                    Comments

                                                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                    Control0..*
                                                    TypeExtension
                                                    Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                    Summarytrue
                                                    Requirements

                                                    Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                    Alternate Namesextensions, user content, modifiers
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                    240. MedicationKnowledge.drugCharacteristic.type
                                                    Definition

                                                    A code specifying which characteristic of the medicine is being described (for example, colour, shape, imprint).

                                                    ShortCode specifying the type of characteristic of medication
                                                    Control0..1
                                                    BindingFor example codes, see medicationKnowledge Characteristic Codes
                                                    (example to http://hl7.org/fhir/ValueSet/medicationknowledge-characteristic|4.0.1)

                                                    A coded concept defining the characteristic types of a medication.

                                                    TypeCodeableConcept
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    242. MedicationKnowledge.drugCharacteristic.value[x]
                                                    Definition

                                                    Description of the characteristic.

                                                    ShortDescription of the characteristic
                                                    Comments

                                                    The description should be provided as a CodeableConcept, SimpleQuantity or an image. The description can be a string only when these others are not available.

                                                    Control0..1
                                                    TypeChoice of: CodeableConcept, string, Quantity(SimpleQuantity), base64Binary
                                                    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                    Is Modifierfalse
                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    244. MedicationKnowledge.contraindication
                                                    Definition

                                                    Potential clinical issue with or between medication(s) (for example, drug-drug interaction, drug-disease contraindication, drug-allergy interaction, etc.).

                                                    ShortPotential clinical issue with or between medication(s)
                                                    Control0..*
                                                    TypeReference(DetectedIssue)
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    246. MedicationKnowledge.contraindication.id
                                                    Definition

                                                    Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                    ShortUnique id for inter-element referencing
                                                    Control0..1
                                                    Typestring
                                                    Is Modifierfalse
                                                    XML FormatIn the XML format, this property is represented as an attribute.
                                                    Summaryfalse
                                                    248. MedicationKnowledge.contraindication.extension
                                                    Definition

                                                    An Extension

                                                    ShortExtension
                                                    Control0..*
                                                    TypeExtension
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                    SlicingThis element introduces a set of slices on MedicationKnowledge.contraindication.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                    • value @ url
                                                    • 250. MedicationKnowledge.contraindication.extension:clinicalUseIssue
                                                      Slice NameclinicalUseIssue
                                                      Definition

                                                      R5: MedicationKnowledge.clinicalUseIssue additional types from child elements (display, identifier, reference, type)

                                                      ShortR5: clinicalUseIssue additional types
                                                      Comments

                                                      Element MedicationKnowledge.clinicalUseIssue is mapped to FHIR R4 element MedicationKnowledge.contraindication as SourceIsBroaderThanTarget. The mappings for MedicationKnowledge.clinicalUseIssue do not cover the following types based on type expansion: display, identifier, reference, type. The standard extension alternate-reference has been mapped as the representation of FHIR R5 element MedicationKnowledge.clinicalUseIssue with unmapped reference targets: ClinicalUseDefinition.

                                                      Control0..1
                                                      TypeExtension(Alternate Reference) (Extension Type: Reference(Resource))
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      252. MedicationKnowledge.contraindication.reference
                                                      Definition

                                                      A reference to a location at which the other resource is found. The reference may be a relative reference, in which case it is relative to the service base URL, or an absolute URL that resolves to the location where the resource is found. The reference may be version specific or not. If the reference is not to a FHIR RESTful server, then it should be assumed to be version specific. Internal fragment references (start with '#') refer to contained resources.

                                                      ShortLiteral reference, Relative, internal or absolute URL
                                                      Comments

                                                      Using absolute URLs provides a stable scalable approach suitable for a cloud/web context, while using relative/logical references provides a flexible approach suitable for use when trading across closed eco-system boundaries. Absolute URLs do not need to point to a FHIR RESTful server, though this is the preferred approach. If the URL conforms to the structure "/[type]/[id]" then it should be assumed that the reference is to a FHIR RESTful server.

                                                      Control0..1
                                                      This element is affected by the following invariants: ref-1
                                                      Typestring
                                                      Is Modifierfalse
                                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                      Summarytrue
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      254. MedicationKnowledge.contraindication.type
                                                      Definition

                                                      The expected type of the target of the reference. If both Reference.type and Reference.reference are populated and Reference.reference is a FHIR URL, both SHALL be consistent.

                                                      The type is the Canonical URL of Resource Definition that is the type this reference refers to. References are URLs that are relative to http://hl7.org/fhir/StructureDefinition/ e.g. "Patient" is a reference to http://hl7.org/fhir/StructureDefinition/Patient. Absolute URLs are only allowed for logical models (and can only be used in references in logical models, not resources).

                                                      ShortType the reference refers to (e.g. "Patient")
                                                      Comments

                                                      This element is used to indicate the type of the target of the reference. This may be used which ever of the other elements are populated (or not). In some cases, the type of the target may be determined by inspection of the reference (e.g. a RESTful URL) or by resolving the target of the reference; if both the type and a reference is provided, the reference SHALL resolve to a resource of the same type as that specified.

                                                      Control0..1
                                                      BindingUnless not suitable, these codes SHALL be taken from ResourceType .
                                                      (extensible to http://hl7.org/fhir/ValueSet/resource-types|4.0.1)

                                                      Aa resource (or, for logical models, the URI of the logical model).

                                                      Typeuri
                                                      Is Modifierfalse
                                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                      Summarytrue
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      256. MedicationKnowledge.contraindication.identifier
                                                      Definition

                                                      An identifier for the target resource. This is used when there is no way to reference the other resource directly, either because the entity it represents is not available through a FHIR server, or because there is no way for the author of the resource to convert a known identifier to an actual location. There is no requirement that a Reference.identifier point to something that is actually exposed as a FHIR instance, but it SHALL point to a business concept that would be expected to be exposed as a FHIR instance, and that instance would need to be of a FHIR resource type allowed by the reference.

                                                      ShortLogical reference, when literal reference is not known
                                                      Comments

                                                      When an identifier is provided in place of a reference, any system processing the reference will only be able to resolve the identifier to a reference if it understands the business context in which the identifier is used. Sometimes this is global (e.g. a national identifier) but often it is not. For this reason, none of the useful mechanisms described for working with references (e.g. chaining, includes) are possible, nor should servers be expected to be able resolve the reference. Servers may accept an identifier based reference untouched, resolve it, and/or reject it - see CapabilityStatement.rest.resource.referencePolicy.

                                                      When both an identifier and a literal reference are provided, the literal reference is preferred. Applications processing the resource are allowed - but not required - to check that the identifier matches the literal reference

                                                      Applications converting a logical reference to a literal reference may choose to leave the logical reference present, or remove it.

                                                      Reference is intended to point to a structure that can potentially be expressed as a FHIR resource, though there is no need for it to exist as an actual FHIR resource instance - except in as much as an application wishes to actual find the target of the reference. The content referred to be the identifier must meet the logical constraints implied by any limitations on what resource types are permitted for the reference. For example, it would not be legitimate to send the identifier for a drug prescription if the type were Reference(Observation|DiagnosticReport). One of the use-cases for Reference.identifier is the situation where no FHIR representation exists (where the type is Reference (Any).

                                                      NoteThis is a business identifier, not a resource identifier (see discussion)
                                                      Control0..1
                                                      TypeIdentifier
                                                      Is Modifierfalse
                                                      Summarytrue
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      258. MedicationKnowledge.contraindication.display
                                                      Definition

                                                      Plain text narrative that identifies the resource in addition to the resource reference.

                                                      ShortText alternative for the resource
                                                      Comments

                                                      This is generally not the same as the Resource.text of the referenced resource. The purpose is to identify what's being referenced, not to fully describe it.

                                                      Control0..1
                                                      Typestring
                                                      Is Modifierfalse
                                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                      Summarytrue
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      260. MedicationKnowledge.regulatory
                                                      Definition

                                                      Regulatory information about a medication.

                                                      ShortRegulatory information about a medication
                                                      Control0..*
                                                      TypeBackboneElement
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      262. MedicationKnowledge.regulatory.id
                                                      Definition

                                                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                      ShortUnique id for inter-element referencing
                                                      Control0..1
                                                      Typestring
                                                      Is Modifierfalse
                                                      XML FormatIn the XML format, this property is represented as an attribute.
                                                      Summaryfalse
                                                      264. MedicationKnowledge.regulatory.extension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                      ShortAdditional content defined by implementations
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Alternate Namesextensions, user content
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      266. MedicationKnowledge.regulatory.modifierExtension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                      Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                      ShortExtensions that cannot be ignored even if unrecognized
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                      Summarytrue
                                                      Requirements

                                                      Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                      Alternate Namesextensions, user content, modifiers
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      268. MedicationKnowledge.regulatory.regulatoryAuthority
                                                      Definition

                                                      The authority that is specifying the regulations.

                                                      ShortSpecifies the authority of the regulation
                                                      Control1..1
                                                      TypeReference(Organization)
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      270. MedicationKnowledge.regulatory.substitution
                                                      Definition

                                                      Specifies if changes are allowed when dispensing a medication from a regulatory perspective.

                                                      ShortSpecifies if changes are allowed when dispensing a medication from a regulatory perspective
                                                      Control0..*
                                                      TypeBackboneElement
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      272. MedicationKnowledge.regulatory.substitution.id
                                                      Definition

                                                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                      ShortUnique id for inter-element referencing
                                                      Control0..1
                                                      Typestring
                                                      Is Modifierfalse
                                                      XML FormatIn the XML format, this property is represented as an attribute.
                                                      Summaryfalse
                                                      274. MedicationKnowledge.regulatory.substitution.extension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                      ShortAdditional content defined by implementations
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Alternate Namesextensions, user content
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      276. MedicationKnowledge.regulatory.substitution.modifierExtension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                      Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                      ShortExtensions that cannot be ignored even if unrecognized
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                      Summarytrue
                                                      Requirements

                                                      Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                      Alternate Namesextensions, user content, modifiers
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      278. MedicationKnowledge.regulatory.substitution.type
                                                      Definition

                                                      Specifies the type of substitution allowed.

                                                      ShortSpecifies the type of substitution allowed
                                                      Control1..1
                                                      TypeCodeableConcept
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      280. MedicationKnowledge.regulatory.substitution.allowed
                                                      Definition

                                                      Specifies if regulation allows for changes in the medication when dispensing.

                                                      ShortSpecifies if regulation allows for changes in the medication when dispensing
                                                      Control1..1
                                                      Typeboolean
                                                      Is Modifierfalse
                                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      282. MedicationKnowledge.regulatory.schedule
                                                      Definition

                                                      Specifies the schedule of a medication in jurisdiction.

                                                      ShortSpecifies the schedule of a medication in jurisdiction
                                                      Control0..*
                                                      TypeBackboneElement
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      284. MedicationKnowledge.regulatory.schedule.id
                                                      Definition

                                                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                      ShortUnique id for inter-element referencing
                                                      Control0..1
                                                      Typestring
                                                      Is Modifierfalse
                                                      XML FormatIn the XML format, this property is represented as an attribute.
                                                      Summaryfalse
                                                      286. MedicationKnowledge.regulatory.schedule.extension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                      ShortAdditional content defined by implementations
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Alternate Namesextensions, user content
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      288. MedicationKnowledge.regulatory.schedule.modifierExtension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                      Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                      ShortExtensions that cannot be ignored even if unrecognized
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                      Summarytrue
                                                      Requirements

                                                      Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                      Alternate Namesextensions, user content, modifiers
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      290. MedicationKnowledge.regulatory.schedule.schedule
                                                      Definition

                                                      Specifies the specific drug schedule.

                                                      ShortSpecifies the specific drug schedule
                                                      Control1..1
                                                      TypeCodeableConcept
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      292. MedicationKnowledge.regulatory.maxDispense
                                                      Definition

                                                      The maximum number of units of the medication that can be dispensed in a period.

                                                      ShortThe maximum number of units of the medication that can be dispensed in a period
                                                      Control0..1
                                                      TypeBackboneElement
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      294. MedicationKnowledge.regulatory.maxDispense.id
                                                      Definition

                                                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                      ShortUnique id for inter-element referencing
                                                      Control0..1
                                                      Typestring
                                                      Is Modifierfalse
                                                      XML FormatIn the XML format, this property is represented as an attribute.
                                                      Summaryfalse
                                                      296. MedicationKnowledge.regulatory.maxDispense.extension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                      ShortAdditional content defined by implementations
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Alternate Namesextensions, user content
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      298. MedicationKnowledge.regulatory.maxDispense.modifierExtension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                      Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                      ShortExtensions that cannot be ignored even if unrecognized
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                      Summarytrue
                                                      Requirements

                                                      Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                      Alternate Namesextensions, user content, modifiers
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      300. MedicationKnowledge.regulatory.maxDispense.quantity
                                                      Definition

                                                      The maximum number of units of the medication that can be dispensed.

                                                      ShortThe maximum number of units of the medication that can be dispensed
                                                      Control1..1
                                                      TypeQuantity(SimpleQuantity)
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      302. MedicationKnowledge.regulatory.maxDispense.period
                                                      Definition

                                                      The period that applies to the maximum number of units.

                                                      ShortThe period that applies to the maximum number of units
                                                      Control0..1
                                                      TypeDuration
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      304. MedicationKnowledge.kinetics
                                                      Definition

                                                      The time course of drug absorption, distribution, metabolism and excretion of a medication from the body.

                                                      ShortThe time course of drug absorption, distribution, metabolism and excretion of a medication from the body
                                                      Control0..*
                                                      TypeBackboneElement
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      306. MedicationKnowledge.kinetics.id
                                                      Definition

                                                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                      ShortUnique id for inter-element referencing
                                                      Control0..1
                                                      Typestring
                                                      Is Modifierfalse
                                                      XML FormatIn the XML format, this property is represented as an attribute.
                                                      Summaryfalse
                                                      308. MedicationKnowledge.kinetics.extension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                      ShortAdditional content defined by implementations
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Alternate Namesextensions, user content
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      310. MedicationKnowledge.kinetics.modifierExtension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                      Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                      ShortExtensions that cannot be ignored even if unrecognized
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                      Summarytrue
                                                      Requirements

                                                      Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                      Alternate Namesextensions, user content, modifiers
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      312. MedicationKnowledge.kinetics.areaUnderCurve
                                                      Definition

                                                      The drug concentration measured at certain discrete points in time.

                                                      ShortThe drug concentration measured at certain discrete points in time
                                                      Control0..*
                                                      TypeQuantity(SimpleQuantity)
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      314. MedicationKnowledge.kinetics.lethalDose50
                                                      Definition

                                                      The median lethal dose of a drug.

                                                      ShortThe median lethal dose of a drug
                                                      Control0..*
                                                      TypeQuantity(SimpleQuantity)
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      316. MedicationKnowledge.kinetics.halfLifePeriod
                                                      Definition

                                                      The time required for any specified property (e.g., the concentration of a substance in the body) to decrease by half.

                                                      ShortTime required for concentration in the body to decrease by half
                                                      Control0..1
                                                      TypeDuration
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))