Cross-version Extension for R5.SubstanceDefinition for use in FHIR R4 - Definitions - FHIR Cross-Version Extensions package for FHIR R4 from FHIR R5 v0.0.1-snapshot-2

FHIR Cross-Version Extensions package for FHIR R4 from FHIR R5 - Version 0.0.1-snapshot-2. See the Directory of published versions

Extension: Ext_R5_SubstanceDefinition - Detailed Descriptions

Page standards status: Informative

Maturity Level: 0

Definitions for the ext-R5-SubstanceDefinition extension.

Differential Elements Table
Key Elements Table
Snapshot Elements Table

Guidance on how to interpret the contents of this table can be foundhere

0. Extension
Definition	This cross-version extension represents SubstanceDefinition from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The detailed description of a substance, typically at a level beyond what is used for prescribing
Control	0..*
2. Extension.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
4. Extension.extension:version
Slice Name	version
Definition	This cross-version extension represents SubstanceDefinition.version from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A business level version identifier of the substance
Control	0..1
6. Extension.extension:version.url
Control	1..1
Fixed Value	`version`
8. Extension.extension:version.value[x]
Definition	This cross-version extension represents SubstanceDefinition.version from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A business level version identifier of the substance
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
10. Extension.extension:status
Slice Name	status
Definition	This cross-version extension represents SubstanceDefinition.status from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Status of substance within the catalogue e.g. active, retired
Control	0..1
12. Extension.extension:status.url
Control	1..1
Fixed Value	`status`
14. Extension.extension:status.value[x]
Definition	This cross-version extension represents SubstanceDefinition.status from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Status of substance within the catalogue e.g. active, retired
Binding	The codes SHOULD be taken from R5_publication_status_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-publication-status-for-R4\|0.0.1-snapshot-2`) The lifecycle status of an artifact.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
16. Extension.extension:classification
Slice Name	classification
Definition	A high level categorization, e.g. polymer or nucleic acid, or food, chemical, biological, or a lower level such as the general types of polymer (linear or branch chain) or type of impurity (process related or contaminant).
Short	A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity
Control	0..*
18. Extension.extension:classification.url
Control	1..1
Fixed Value	`classification`
20. Extension.extension:classification.value[x]
Definition	A high level categorization, e.g. polymer or nucleic acid, or food, chemical, biological, or a lower level such as the general types of polymer (linear or branch chain) or type of impurity (process related or contaminant).
Short	A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
22. Extension.extension:domain
Slice Name	domain
Definition	This cross-version extension represents SubstanceDefinition.domain from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If the substance applies to human or veterinary use
Control	0..1
24. Extension.extension:domain.url
Control	1..1
Fixed Value	`domain`
26. Extension.extension:domain.value[x]
Definition	This cross-version extension represents SubstanceDefinition.domain from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If the substance applies to human or veterinary use
Binding	For example codes, see R5_medicinal_product_domain_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-medicinal-product-domain-for-R4\|0.0.1-snapshot-2`) Applicable domain for this product (e.g. human, veterinary).
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
28. Extension.extension:grade
Slice Name	grade
Definition	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, Ph. Eur, JP, BP, Company Standard).
Short	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP)
Control	0..*
30. Extension.extension:grade.url
Control	1..1
Fixed Value	`grade`
32. Extension.extension:grade.value[x]
Definition	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, Ph. Eur, JP, BP, Company Standard).
Short	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP)
Binding	For example codes, see R5_substance_grade_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-grade-for-R4\|0.0.1-snapshot-2`) The quality standard, established benchmark, to which a substance complies
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
34. Extension.extension:description
Slice Name	description
Definition	This cross-version extension represents SubstanceDefinition.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual description of the substance
Control	0..1
36. Extension.extension:description.url
Control	1..1
Fixed Value	`description`
38. Extension.extension:description.value[x]
Definition	This cross-version extension represents SubstanceDefinition.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual description of the substance
Type	markdown
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
40. Extension.extension:informationSource
Slice Name	informationSource
Definition	This cross-version extension represents SubstanceDefinition.informationSource from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Control	0..*
42. Extension.extension:informationSource.url
Control	1..1
Fixed Value	`informationSource`
44. Extension.extension:informationSource.value[x]
Definition	This cross-version extension represents SubstanceDefinition.informationSource from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
46. Extension.extension:note
Slice Name	note
Definition	This cross-version extension represents SubstanceDefinition.note from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual comment about the substance's catalogue or registry record
Control	0..*
48. Extension.extension:note.url
Control	1..1
Fixed Value	`note`
50. Extension.extension:note.value[x]
Definition	This cross-version extension represents SubstanceDefinition.note from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual comment about the substance's catalogue or registry record
Type	Annotation
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
52. Extension.extension:manufacturer
Slice Name	manufacturer
Definition	The entity that creates, makes, produces or fabricates the substance. This is a set of potential manufacturers but is not necessarily comprehensive.
Short	The entity that creates, makes, produces or fabricates the substance
Control	0..*
54. Extension.extension:manufacturer.url
Control	1..1
Fixed Value	`manufacturer`
56. Extension.extension:manufacturer.value[x]
Definition	The entity that creates, makes, produces or fabricates the substance. This is a set of potential manufacturers but is not necessarily comprehensive.
Short	The entity that creates, makes, produces or fabricates the substance
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
58. Extension.extension:supplier
Slice Name	supplier
Definition	An entity that is the source for the substance. It may be different from the manufacturer. Supplier is synonymous to a distributor.
Short	An entity that is the source for the substance. It may be different from the manufacturer
Control	0..*
60. Extension.extension:supplier.url
Control	1..1
Fixed Value	`supplier`
62. Extension.extension:supplier.value[x]
Definition	An entity that is the source for the substance. It may be different from the manufacturer. Supplier is synonymous to a distributor.
Short	An entity that is the source for the substance. It may be different from the manufacturer
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
64. Extension.extension:moiety
Slice Name	moiety
Definition	This cross-version extension represents SubstanceDefinition.moiety from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Moiety, for structural modifications
Control	0..*
66. Extension.extension:moiety.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
68. Extension.extension:moiety.extension:role
Slice Name	role
Definition	This cross-version extension represents SubstanceDefinition.moiety.role from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Role that the moiety is playing
Control	0..1
70. Extension.extension:moiety.extension:role.url
Control	1..1
Fixed Value	`role`
72. Extension.extension:moiety.extension:role.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.role from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Role that the moiety is playing
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
74. Extension.extension:moiety.extension:identifier
Slice Name	identifier
Definition	This cross-version extension represents SubstanceDefinition.moiety.identifier from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Identifier by which this moiety substance is known
Control	0..1
76. Extension.extension:moiety.extension:identifier.url
Control	1..1
Fixed Value	`identifier`
78. Extension.extension:moiety.extension:identifier.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.identifier from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Identifier by which this moiety substance is known
Type	Identifier
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
80. Extension.extension:moiety.extension:name
Slice Name	name
Definition	This cross-version extension represents SubstanceDefinition.moiety.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual name for this moiety substance
Control	0..1
82. Extension.extension:moiety.extension:name.url
Control	1..1
Fixed Value	`name`
84. Extension.extension:moiety.extension:name.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual name for this moiety substance
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
86. Extension.extension:moiety.extension:stereochemistry
Slice Name	stereochemistry
Definition	This cross-version extension represents SubstanceDefinition.moiety.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry type
Control	0..1
88. Extension.extension:moiety.extension:stereochemistry.url
Control	1..1
Fixed Value	`stereochemistry`
90. Extension.extension:moiety.extension:stereochemistry.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry type
Binding	For example codes, see R5_substance_stereochemistry_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-stereochemistry-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
92. Extension.extension:moiety.extension:opticalActivity
Slice Name	opticalActivity
Definition	This cross-version extension represents SubstanceDefinition.moiety.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity type
Control	0..1
94. Extension.extension:moiety.extension:opticalActivity.url
Control	1..1
Fixed Value	`opticalActivity`
96. Extension.extension:moiety.extension:opticalActivity.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity type
Binding	For example codes, see R5_substance_optical_activity_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-optical-activity-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
98. Extension.extension:moiety.extension:molecularFormula
Slice Name	molecularFormula
Definition	Molecular formula for this moiety of this substance, typically using the Hill system.
Short	Molecular formula for this moiety (e.g. with the Hill system)
Control	0..1
100. Extension.extension:moiety.extension:molecularFormula.url
Control	1..1
Fixed Value	`molecularFormula`
102. Extension.extension:moiety.extension:molecularFormula.value[x]
Definition	Molecular formula for this moiety of this substance, typically using the Hill system.
Short	Molecular formula for this moiety (e.g. with the Hill system)
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
104. Extension.extension:moiety.extension:amount[x]
Slice Name	amount[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.amount[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Quantitative value for this moiety
Control	0..1
106. Extension.extension:moiety.extension:amount[x].url
Control	1..1
Fixed Value	`amount[x]`
108. Extension.extension:moiety.extension:amount[x].value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.amount[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Quantitative value for this moiety
Type	Choice of: Quantity, string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
110. Extension.extension:moiety.extension:measurementType
Slice Name	measurementType
Definition	The measurement type of the quantitative value. In capturing the actual relative amounts of substances or molecular fragments it may be necessary to indicate whether the amount refers to, for example, a mole ratio or weight ratio.
Short	The measurement type of the quantitative value
Control	0..1
112. Extension.extension:moiety.extension:measurementType.url
Control	1..1
Fixed Value	`measurementType`
114. Extension.extension:moiety.extension:measurementType.value[x]
Definition	The measurement type of the quantitative value. In capturing the actual relative amounts of substances or molecular fragments it may be necessary to indicate whether the amount refers to, for example, a mole ratio or weight ratio.
Short	The measurement type of the quantitative value
Binding	For example codes, see R5_substance_amount_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-amount-type-for-R4\|0.0.1-snapshot-2`) The relationship between two substance types.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
116. Extension.extension:moiety.url
Control	1..1
Fixed Value	`moiety`
118. Extension.extension:characterization
Slice Name	characterization
Definition	This cross-version extension represents SubstanceDefinition.characterization from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General specifications for this substance
Control	0..*
120. Extension.extension:characterization.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
122. Extension.extension:characterization.extension:technique
Slice Name	technique
Definition	The method used to elucidate the characterization of the drug substance. Example: HPLC.
Short	The method used to find the characterization e.g. HPLC
Control	0..1
124. Extension.extension:characterization.extension:technique.url
Control	1..1
Fixed Value	`technique`
126. Extension.extension:characterization.extension:technique.value[x]
Definition	The method used to elucidate the characterization of the drug substance. Example: HPLC.
Short	The method used to find the characterization e.g. HPLC
Binding	For example codes, see R5_substance_structure_technique_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-structure-technique-for-R4\|0.0.1-snapshot-2`) The method used to elucidate the characterization of the drug substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
128. Extension.extension:characterization.extension:form
Slice Name	form
Definition	This cross-version extension represents SubstanceDefinition.characterization.form from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt form
Control	0..1
130. Extension.extension:characterization.extension:form.url
Control	1..1
Fixed Value	`form`
132. Extension.extension:characterization.extension:form.value[x]
Definition	This cross-version extension represents SubstanceDefinition.characterization.form from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt form
Binding	For example codes, see R5_substance_form_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-form-for-R4\|0.0.1-snapshot-2`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
134. Extension.extension:characterization.extension:description
Slice Name	description
Definition	This cross-version extension represents SubstanceDefinition.characterization.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The description or justification in support of the interpretation of the data file
Control	0..1
136. Extension.extension:characterization.extension:description.url
Control	1..1
Fixed Value	`description`
138. Extension.extension:characterization.extension:description.value[x]
Definition	This cross-version extension represents SubstanceDefinition.characterization.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The description or justification in support of the interpretation of the data file
Type	markdown
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
140. Extension.extension:characterization.extension:file
Slice Name	file
Definition	This cross-version extension represents SubstanceDefinition.characterization.file from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysis
Control	0..*
142. Extension.extension:characterization.extension:file.url
Control	1..1
Fixed Value	`file`
144. Extension.extension:characterization.extension:file.value[x]
Definition	This cross-version extension represents SubstanceDefinition.characterization.file from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysis
Type	Attachment
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
146. Extension.extension:characterization.url
Control	1..1
Fixed Value	`characterization`
148. Extension.extension:property
Slice Name	property
Definition	This cross-version extension represents SubstanceDefinition.property from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General specifications for this substance
Control	0..*
150. Extension.extension:property.extension
Control	1..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
152. Extension.extension:property.extension:type
Slice Name	type
Definition	This cross-version extension represents SubstanceDefinition.property.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A code expressing the type of property
Control	1..1
154. Extension.extension:property.extension:type.url
Control	1..1
Fixed Value	`type`
156. Extension.extension:property.extension:type.value[x]
Definition	This cross-version extension represents SubstanceDefinition.property.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A code expressing the type of property
Binding	For example codes, see R5_product_characteristic_codes_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-product-characteristic-codes-for-R4\|0.0.1-snapshot-2`) This value set includes all observable entity codes from SNOMED CT - provided as an exemplar value set.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
158. Extension.extension:property.extension:value[x]
Slice Name	value[x]
Definition	This cross-version extension represents SubstanceDefinition.property.value[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A value for the property
Control	0..1
160. Extension.extension:property.extension:value[x].url
Control	1..1
Fixed Value	`value[x]`
162. Extension.extension:property.extension:value[x].value[x]
Definition	This cross-version extension represents SubstanceDefinition.property.value[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A value for the property
Type	Choice of: CodeableConcept, Quantity, date, boolean, Attachment
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
164. Extension.extension:property.url
Control	1..1
Fixed Value	`property`
166. Extension.extension:referenceInformation
Slice Name	referenceInformation
Definition	This cross-version extension represents SubstanceDefinition.referenceInformation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General information detailing this substance
Control	0..1
168. Extension.extension:referenceInformation.url
Control	1..1
Fixed Value	`referenceInformation`
170. Extension.extension:referenceInformation.value[x]
Definition	This cross-version extension represents SubstanceDefinition.referenceInformation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General information detailing this substance
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
172. Extension.extension:molecularWeight
Slice Name	molecularWeight
Definition	The average mass of a molecule of a compound compared to 1/12 the mass of carbon 12 and calculated as the sum of the atomic weights of the constituent atoms.
Short	The average mass of a molecule of a compound
Control	0..*
174. Extension.extension:molecularWeight.extension
Control	1..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
176. Extension.extension:molecularWeight.extension:method
Slice Name	method
Definition	The method by which the molecular weight was determined.
Short	The method by which the weight was determined
Control	0..1
178. Extension.extension:molecularWeight.extension:method.url
Control	1..1
Fixed Value	`method`
180. Extension.extension:molecularWeight.extension:method.value[x]
Definition	The method by which the molecular weight was determined.
Short	The method by which the weight was determined
Binding	For example codes, see R5_substance_weight_method_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-weight-method-for-R4\|0.0.1-snapshot-2`) The method by which the substance weight was measured.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
182. Extension.extension:molecularWeight.extension:type
Slice Name	type
Definition	Type of molecular weight such as exact, average (also known as. number average), weight average.
Short	Type of molecular weight e.g. exact, average, weight average
Control	0..1
184. Extension.extension:molecularWeight.extension:type.url
Control	1..1
Fixed Value	`type`
186. Extension.extension:molecularWeight.extension:type.value[x]
Definition	Type of molecular weight such as exact, average (also known as. number average), weight average.
Short	Type of molecular weight e.g. exact, average, weight average
Binding	For example codes, see R5_substance_weight_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-weight-type-for-R4\|0.0.1-snapshot-2`) The type of substance weight measurement.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
188. Extension.extension:molecularWeight.extension:amount
Slice Name	amount
Definition	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field.
Short	Used to capture quantitative values for a variety of elements
Control	1..1
190. Extension.extension:molecularWeight.extension:amount.url
Control	1..1
Fixed Value	`amount`
192. Extension.extension:molecularWeight.extension:amount.value[x]
Definition	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field.
Short	Used to capture quantitative values for a variety of elements
Type	Quantity
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
194. Extension.extension:molecularWeight.url
Control	1..1
Fixed Value	`molecularWeight`
196. Extension.extension:structure
Slice Name	structure
Definition	This cross-version extension represents SubstanceDefinition.structure from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Structural information
Control	0..1
198. Extension.extension:structure.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
200. Extension.extension:structure.extension:stereochemistry
Slice Name	stereochemistry
Definition	This cross-version extension represents SubstanceDefinition.structure.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry type
Control	0..1
202. Extension.extension:structure.extension:stereochemistry.url
Control	1..1
Fixed Value	`stereochemistry`
204. Extension.extension:structure.extension:stereochemistry.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry type
Binding	For example codes, see R5_substance_stereochemistry_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-stereochemistry-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
206. Extension.extension:structure.extension:opticalActivity
Slice Name	opticalActivity
Definition	This cross-version extension represents SubstanceDefinition.structure.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity type
Control	0..1
208. Extension.extension:structure.extension:opticalActivity.url
Control	1..1
Fixed Value	`opticalActivity`
210. Extension.extension:structure.extension:opticalActivity.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity type
Binding	For example codes, see R5_substance_optical_activity_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-optical-activity-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
212. Extension.extension:structure.extension:molecularFormula
Slice Name	molecularFormula
Definition	This cross-version extension represents SubstanceDefinition.structure.molecularFormula from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An expression which states the number and type of atoms present in a molecule of a substance
Control	0..1
214. Extension.extension:structure.extension:molecularFormula.url
Control	1..1
Fixed Value	`molecularFormula`
216. Extension.extension:structure.extension:molecularFormula.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.molecularFormula from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An expression which states the number and type of atoms present in a molecule of a substance
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
218. Extension.extension:structure.extension:molecularFormulaByMoiety
Slice Name	molecularFormulaByMoiety
Definition	Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical, each moiety separated by a dot.
Short	Specified per moiety according to the Hill system
Control	0..1
220. Extension.extension:structure.extension:molecularFormulaByMoiety.url
Control	1..1
Fixed Value	`molecularFormulaByMoiety`
222. Extension.extension:structure.extension:molecularFormulaByMoiety.value[x]
Definition	Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical, each moiety separated by a dot.
Short	Specified per moiety according to the Hill system
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
224. Extension.extension:structure.extension:molecularWeight
Slice Name	molecularWeight
Definition	The molecular weight or weight range (for proteins, polymers or nucleic acids).
Short	The molecular weight or weight range
Control	0..1
226. Extension.extension:structure.extension:molecularWeight.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
228. Extension.extension:structure.extension:molecularWeight.extension:_datatype
Slice Name	_datatype
Definition	Data type name for SubstanceDefinition.structure.molecularWeight from FHIR R5
Short	Data type name for SubstanceDefinition.structure.molecularWeight from FHIR R5
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
230. Extension.extension:structure.extension:molecularWeight.extension:_datatype.value[x]
Comments	Must be: SubstanceDefinition.molecularWeight
Control	1..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Fixed Value	`SubstanceDefinition.molecularWeight`
232. Extension.extension:structure.extension:molecularWeight.url
Control	1..1
Fixed Value	`molecularWeight`
234. Extension.extension:structure.extension:technique
Slice Name	technique
Definition	The method used to elucidate the structure of the drug substance. Examples: X-ray, NMR, Peptide mapping, Ligand binding assay.
Short	The method used to find the structure e.g. X-ray, NMR
Control	0..*
236. Extension.extension:structure.extension:technique.url
Control	1..1
Fixed Value	`technique`
238. Extension.extension:structure.extension:technique.value[x]
Definition	The method used to elucidate the structure of the drug substance. Examples: X-ray, NMR, Peptide mapping, Ligand binding assay.
Short	The method used to find the structure e.g. X-ray, NMR
Binding	For example codes, see R5_substance_structure_technique_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-structure-technique-for-R4\|0.0.1-snapshot-2`) The method used to elucidate the structure of the drug substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
240. Extension.extension:structure.extension:sourceDocument
Slice Name	sourceDocument
Definition	The source of information about the structure.
Short	Source of information for the structure
Control	0..*
242. Extension.extension:structure.extension:sourceDocument.url
Control	1..1
Fixed Value	`sourceDocument`
244. Extension.extension:structure.extension:sourceDocument.value[x]
Definition	The source of information about the structure.
Short	Source of information for the structure
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
246. Extension.extension:structure.extension:representation
Slice Name	representation
Definition	This cross-version extension represents SubstanceDefinition.structure.representation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A depiction of the structure of the substance
Control	0..*
248. Extension.extension:structure.extension:representation.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
250. Extension.extension:structure.extension:representation.extension:type
Slice Name	type
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The kind of structural representation (e.g. full, partial)
Control	0..1
252. Extension.extension:structure.extension:representation.extension:type.url
Control	1..1
Fixed Value	`type`
254. Extension.extension:structure.extension:representation.extension:type.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The kind of structural representation (e.g. full, partial)
Binding	For example codes, see R5_substance_representation_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-representation-type-for-R4\|0.0.1-snapshot-2`) A format of a substance representation.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
256. Extension.extension:structure.extension:representation.extension:representation
Slice Name	representation
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.representation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The structural representation as a text string in a standard format
Control	0..1
258. Extension.extension:structure.extension:representation.extension:representation.url
Control	1..1
Fixed Value	`representation`
260. Extension.extension:structure.extension:representation.extension:representation.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.representation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The structural representation as a text string in a standard format
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
262. Extension.extension:structure.extension:representation.extension:format
Slice Name	format
Definition	The format of the representation e.g. InChI, SMILES, MOLFILE, CDX, SDF, PDB, mmCIF. The logical content type rather than the physical file format of a document.
Short	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format)
Control	0..1
264. Extension.extension:structure.extension:representation.extension:format.url
Control	1..1
Fixed Value	`format`
266. Extension.extension:structure.extension:representation.extension:format.value[x]
Definition	The format of the representation e.g. InChI, SMILES, MOLFILE, CDX, SDF, PDB, mmCIF. The logical content type rather than the physical file format of a document.
Short	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format)
Binding	For example codes, see R5_substance_representation_format_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-representation-format-for-R4\|0.0.1-snapshot-2`) A format of a substance representation.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
268. Extension.extension:structure.extension:representation.extension:document
Slice Name	document
Definition	An attached file with the structural representation e.g. a molecular structure graphic of the substance, a JCAMP or AnIML file.
Short	An attachment with the structural representation e.g. a structure graphic or AnIML file
Control	0..1
270. Extension.extension:structure.extension:representation.extension:document.url
Control	1..1
Fixed Value	`document`
272. Extension.extension:structure.extension:representation.extension:document.value[x]
Definition	An attached file with the structural representation e.g. a molecular structure graphic of the substance, a JCAMP or AnIML file.
Short	An attachment with the structural representation e.g. a structure graphic or AnIML file
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
274. Extension.extension:structure.extension:representation.url
Control	1..1
Fixed Value	`representation`
276. Extension.extension:structure.url
Control	1..1
Fixed Value	`structure`
278. Extension.extension:name
Slice Name	name
Definition	This cross-version extension represents SubstanceDefinition.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Names applicable to this substance
Control	0..*
280. Extension.extension:name.extension
Control	1..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
282. Extension.extension:name.extension:name
Slice Name	name
Definition	This cross-version extension represents SubstanceDefinition.name.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The actual name
Control	1..1
284. Extension.extension:name.extension:name.url
Control	1..1
Fixed Value	`name`
286. Extension.extension:name.extension:name.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The actual name
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
288. Extension.extension:name.extension:type
Slice Name	type
Definition	Name type, for example 'systematic', 'scientific, 'brand'.
Short	Name type e.g. 'systematic', 'scientific, 'brand'
Control	0..1
290. Extension.extension:name.extension:type.url
Control	1..1
Fixed Value	`type`
292. Extension.extension:name.extension:type.value[x]
Definition	Name type, for example 'systematic', 'scientific, 'brand'.
Short	Name type e.g. 'systematic', 'scientific, 'brand'
Binding	For example codes, see R5_substance_name_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-name-type-for-R4\|0.0.1-snapshot-2`) The type of a name given to a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
294. Extension.extension:name.extension:status
Slice Name	status
Definition	The status of the name, for example 'current', 'proposed'.
Short	The status of the name e.g. 'current', 'proposed'
Control	0..1
296. Extension.extension:name.extension:status.url
Control	1..1
Fixed Value	`status`
298. Extension.extension:name.extension:status.value[x]
Definition	The status of the name, for example 'current', 'proposed'.
Short	The status of the name e.g. 'current', 'proposed'
Binding	The codes SHOULD be taken from R5_publication_status_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-publication-status-for-R4\|0.0.1-snapshot-2`) The lifecycle status of an artifact.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
300. Extension.extension:name.extension:preferred
Slice Name	preferred
Definition	This cross-version extension represents SubstanceDefinition.name.preferred from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If this is the preferred name for this substance
Control	0..1
302. Extension.extension:name.extension:preferred.url
Control	1..1
Fixed Value	`preferred`
304. Extension.extension:name.extension:preferred.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.preferred from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If this is the preferred name for this substance
Type	boolean
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
306. Extension.extension:name.extension:language
Slice Name	language
Definition	This cross-version extension represents SubstanceDefinition.name.language from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Human language that the name is written in
Control	0..*
308. Extension.extension:name.extension:language.url
Control	1..1
Fixed Value	`language`
310. Extension.extension:name.extension:language.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.language from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Human language that the name is written in
Binding	The codes SHALL be taken from AllLanguages (required to `http://hl7.org/fhir/ValueSet/all-languages\|4.0.1`) IETF language tag for a human language
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
312. Extension.extension:name.extension:domain
Slice Name	domain
Definition	The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive.
Short	The use context of this name e.g. as an active ingredient or as a food colour additive
Control	0..*
314. Extension.extension:name.extension:domain.url
Control	1..1
Fixed Value	`domain`
316. Extension.extension:name.extension:domain.value[x]
Definition	The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive.
Short	The use context of this name e.g. as an active ingredient or as a food colour additive
Binding	For example codes, see R5_substance_name_domain_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-name-domain-for-R4\|0.0.1-snapshot-2`) The use context of a substance name for example if there is a different name when used as a drug active ingredient as opposed to a food colour additive.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
318. Extension.extension:name.extension:jurisdiction
Slice Name	jurisdiction
Definition	This cross-version extension represents SubstanceDefinition.name.jurisdiction from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The jurisdiction where this name applies
Control	0..*
320. Extension.extension:name.extension:jurisdiction.url
Control	1..1
Fixed Value	`jurisdiction`
322. Extension.extension:name.extension:jurisdiction.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.jurisdiction from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The jurisdiction where this name applies
Binding	For example codes, see R5_jurisdiction_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-jurisdiction-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
324. Extension.extension:name.extension:synonym
Slice Name	synonym
Definition	This cross-version extension represents SubstanceDefinition.name.synonym from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A synonym of this particular name, by which the substance is also known
Control	0..*
326. Extension.extension:name.extension:synonym.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
328. Extension.extension:name.extension:synonym.extension:_datatype
Slice Name	_datatype
Definition	Data type name for SubstanceDefinition.name.synonym from FHIR R5
Short	Data type name for SubstanceDefinition.name.synonym from FHIR R5
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
330. Extension.extension:name.extension:synonym.extension:_datatype.value[x]
Comments	Must be: SubstanceDefinition.name
Control	1..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Fixed Value	`SubstanceDefinition.name`
332. Extension.extension:name.extension:synonym.url
Control	1..1
Fixed Value	`synonym`
334. Extension.extension:name.extension:translation
Slice Name	translation
Definition	This cross-version extension represents SubstanceDefinition.name.translation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A translation for this name into another human language
Control	0..*
336. Extension.extension:name.extension:translation.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
338. Extension.extension:name.extension:translation.extension:_datatype
Slice Name	_datatype
Definition	Data type name for SubstanceDefinition.name.translation from FHIR R5
Short	Data type name for SubstanceDefinition.name.translation from FHIR R5
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
340. Extension.extension:name.extension:translation.extension:_datatype.value[x]
Comments	Must be: SubstanceDefinition.name
Control	1..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Fixed Value	`SubstanceDefinition.name`
342. Extension.extension:name.extension:translation.url
Control	1..1
Fixed Value	`translation`
344. Extension.extension:name.extension:official
Slice Name	official
Definition	This cross-version extension represents SubstanceDefinition.name.official from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Details of the official nature of this name
Control	0..*
346. Extension.extension:name.extension:official.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
348. Extension.extension:name.extension:official.extension:authority
Slice Name	authority
Definition	This cross-version extension represents SubstanceDefinition.name.official.authority from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Which authority uses this official name
Control	0..1
350. Extension.extension:name.extension:official.extension:authority.url
Control	1..1
Fixed Value	`authority`
352. Extension.extension:name.extension:official.extension:authority.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.official.authority from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Which authority uses this official name
Binding	The codes SHOULD be taken from R5_substance_name_authority_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-name-authority-for-R4\|0.0.1-snapshot-2`) An authority that officates substance names.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
354. Extension.extension:name.extension:official.extension:status
Slice Name	status
Definition	The status of the official name, for example 'draft', 'active', 'retired'.
Short	The status of the official name, for example 'draft', 'active'
Control	0..1
356. Extension.extension:name.extension:official.extension:status.url
Control	1..1
Fixed Value	`status`
358. Extension.extension:name.extension:official.extension:status.value[x]
Definition	The status of the official name, for example 'draft', 'active', 'retired'.
Short	The status of the official name, for example 'draft', 'active'
Binding	The codes SHOULD be taken from R5_publication_status_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-publication-status-for-R4\|0.0.1-snapshot-2`) The lifecycle status of an artifact.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
360. Extension.extension:name.extension:official.extension:date
Slice Name	date
Definition	Date of the official name change.
Short	Date of official name change
Control	0..1
362. Extension.extension:name.extension:official.extension:date.url
Control	1..1
Fixed Value	`date`
364. Extension.extension:name.extension:official.extension:date.value[x]
Definition	Date of the official name change.
Short	Date of official name change
Type	dateTime
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
366. Extension.extension:name.extension:official.url
Control	1..1
Fixed Value	`official`
368. Extension.extension:name.extension:source
Slice Name	source
Definition	This cross-version extension represents SubstanceDefinition.name.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Control	0..*
370. Extension.extension:name.extension:source.url
Control	1..1
Fixed Value	`source`
372. Extension.extension:name.extension:source.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
374. Extension.extension:name.url
Control	1..1
Fixed Value	`name`
376. Extension.extension:relationship
Slice Name	relationship
Definition	A link between this substance and another, with details of the relationship.
Short	A link between this substance and another
Control	0..*
378. Extension.extension:relationship.extension
Control	1..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
380. Extension.extension:relationship.extension:substanceDefinition[x]
Slice Name	substanceDefinition[x]
Definition	A pointer to another substance, as a resource or just a representational code.
Short	A pointer to another substance, as a resource or a representational code
Control	0..1
382. Extension.extension:relationship.extension:substanceDefinition[x].url
Control	1..1
Fixed Value	`substanceDefinition[x]`
384. Extension.extension:relationship.extension:substanceDefinition[x].value[x]
Definition	A pointer to another substance, as a resource or just a representational code.
Short	A pointer to another substance, as a resource or a representational code
Type	Choice of: Reference, CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
386. Extension.extension:relationship.extension:type
Slice Name	type
Definition	For example "salt to parent", "active moiety", "starting material", "polymorph", "impurity of".
Short	For example "salt to parent", "active moiety"
Control	1..1
388. Extension.extension:relationship.extension:type.url
Control	1..1
Fixed Value	`type`
390. Extension.extension:relationship.extension:type.value[x]
Definition	For example "salt to parent", "active moiety", "starting material", "polymorph", "impurity of".
Short	For example "salt to parent", "active moiety"
Binding	For example codes, see R5_substance_relationship_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-relationship-type-for-R4\|0.0.1-snapshot-2`) The relationship between two substance types.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
392. Extension.extension:relationship.extension:isDefining
Slice Name	isDefining
Definition	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible substance relationships.
Short	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationships
Control	0..1
394. Extension.extension:relationship.extension:isDefining.url
Control	1..1
Fixed Value	`isDefining`
396. Extension.extension:relationship.extension:isDefining.value[x]
Definition	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible substance relationships.
Short	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationships
Type	boolean
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
398. Extension.extension:relationship.extension:amount[x]
Slice Name	amount[x]
Definition	A numeric factor for the relationship, for instance to express that the salt of a substance has some percentage of the active substance in relation to some other.
Short	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some other
Control	0..1
400. Extension.extension:relationship.extension:amount[x].url
Control	1..1
Fixed Value	`amount[x]`
402. Extension.extension:relationship.extension:amount[x].value[x]
Definition	A numeric factor for the relationship, for instance to express that the salt of a substance has some percentage of the active substance in relation to some other.
Short	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some other
Type	Choice of: Quantity, Ratio, string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
404. Extension.extension:relationship.extension:ratioHighLimitAmount
Slice Name	ratioHighLimitAmount
Definition	This cross-version extension represents SubstanceDefinition.relationship.ratioHighLimitAmount from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	For use when the numeric has an uncertain range
Control	0..1
406. Extension.extension:relationship.extension:ratioHighLimitAmount.url
Control	1..1
Fixed Value	`ratioHighLimitAmount`
408. Extension.extension:relationship.extension:ratioHighLimitAmount.value[x]
Definition	This cross-version extension represents SubstanceDefinition.relationship.ratioHighLimitAmount from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	For use when the numeric has an uncertain range
Type	Ratio
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
410. Extension.extension:relationship.extension:comparator
Slice Name	comparator
Definition	This cross-version extension represents SubstanceDefinition.relationship.comparator from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An operator for the amount, for example "average", "approximately", "less than"
Control	0..1
412. Extension.extension:relationship.extension:comparator.url
Control	1..1
Fixed Value	`comparator`
414. Extension.extension:relationship.extension:comparator.value[x]
Definition	This cross-version extension represents SubstanceDefinition.relationship.comparator from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An operator for the amount, for example "average", "approximately", "less than"
Binding	For example codes, see R5_substance_amount_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-amount-type-for-R4\|0.0.1-snapshot-2`) The relationship between two substance types.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
416. Extension.extension:relationship.extension:source
Slice Name	source
Definition	This cross-version extension represents SubstanceDefinition.relationship.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Control	0..*
418. Extension.extension:relationship.extension:source.url
Control	1..1
Fixed Value	`source`
420. Extension.extension:relationship.extension:source.value[x]
Definition	This cross-version extension represents SubstanceDefinition.relationship.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
422. Extension.extension:relationship.url
Control	1..1
Fixed Value	`relationship`
424. Extension.extension:nucleicAcid
Slice Name	nucleicAcid
Definition	This cross-version extension represents SubstanceDefinition.nucleicAcid from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to nucleic acids
Control	0..1
426. Extension.extension:nucleicAcid.url
Control	1..1
Fixed Value	`nucleicAcid`
428. Extension.extension:nucleicAcid.value[x]
Definition	This cross-version extension represents SubstanceDefinition.nucleicAcid from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to nucleic acids
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
430. Extension.extension:polymer
Slice Name	polymer
Definition	This cross-version extension represents SubstanceDefinition.polymer from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to polymers
Control	0..1
432. Extension.extension:polymer.url
Control	1..1
Fixed Value	`polymer`
434. Extension.extension:polymer.value[x]
Definition	This cross-version extension represents SubstanceDefinition.polymer from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to polymers
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
436. Extension.extension:protein
Slice Name	protein
Definition	This cross-version extension represents SubstanceDefinition.protein from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to proteins
Control	0..1
438. Extension.extension:protein.url
Control	1..1
Fixed Value	`protein`
440. Extension.extension:protein.value[x]
Definition	This cross-version extension represents SubstanceDefinition.protein from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to proteins
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
442. Extension.extension:sourceMaterial
Slice Name	sourceMaterial
Definition	Material or taxonomic/anatomical source for the substance.
Short	Material or taxonomic/anatomical source
Control	0..1
444. Extension.extension:sourceMaterial.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
446. Extension.extension:sourceMaterial.extension:type
Slice Name	type
Definition	A classification that provides the origin of the raw material. Example: cat hair would be an Animal source type.
Short	Classification of the origin of the raw material. e.g. cat hair is an Animal source type
Control	0..1
448. Extension.extension:sourceMaterial.extension:type.url
Control	1..1
Fixed Value	`type`
450. Extension.extension:sourceMaterial.extension:type.value[x]
Definition	A classification that provides the origin of the raw material. Example: cat hair would be an Animal source type.
Short	Classification of the origin of the raw material. e.g. cat hair is an Animal source type
Binding	For example codes, see R5_substance_source_material_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-type-for-R4\|0.0.1-snapshot-2`) A classification that provides the origin of the substance raw material.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
452. Extension.extension:sourceMaterial.extension:genus
Slice Name	genus
Definition	The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
Short	The genus of an organism e.g. the Latin epithet of the plant/animal scientific name
Control	0..1
454. Extension.extension:sourceMaterial.extension:genus.url
Control	1..1
Fixed Value	`genus`
456. Extension.extension:sourceMaterial.extension:genus.value[x]
Definition	The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
Short	The genus of an organism e.g. the Latin epithet of the plant/animal scientific name
Binding	For example codes, see R5_substance_source_material_genus_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-genus-for-R4\|0.0.1-snapshot-2`) The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
458. Extension.extension:sourceMaterial.extension:species
Slice Name	species
Definition	The species of an organism, typically referring to the Latin epithet of the species of the plant/animal.
Short	The species of an organism e.g. the Latin epithet of the species of the plant/animal
Control	0..1
460. Extension.extension:sourceMaterial.extension:species.url
Control	1..1
Fixed Value	`species`
462. Extension.extension:sourceMaterial.extension:species.value[x]
Definition	The species of an organism, typically referring to the Latin epithet of the species of the plant/animal.
Short	The species of an organism e.g. the Latin epithet of the species of the plant/animal
Binding	For example codes, see R5_substance_source_material_species_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-species-for-R4\|0.0.1-snapshot-2`) A species of origin a substance raw material.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
464. Extension.extension:sourceMaterial.extension:part
Slice Name	part
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.part from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An anatomical origin of the source material within an organism
Control	0..1
466. Extension.extension:sourceMaterial.extension:part.url
Control	1..1
Fixed Value	`part`
468. Extension.extension:sourceMaterial.extension:part.value[x]
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.part from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An anatomical origin of the source material within an organism
Binding	For example codes, see R5_substance_source_material_part_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-part-for-R4\|0.0.1-snapshot-2`) An anatomical origin of the source material within an organism.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
470. Extension.extension:sourceMaterial.extension:countryOfOrigin
Slice Name	countryOfOrigin
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.countryOfOrigin from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The country or countries where the material is harvested
Control	0..*
472. Extension.extension:sourceMaterial.extension:countryOfOrigin.url
Control	1..1
Fixed Value	`countryOfOrigin`
474. Extension.extension:sourceMaterial.extension:countryOfOrigin.value[x]
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.countryOfOrigin from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The country or countries where the material is harvested
Binding	The codes SHALL be taken from R5_country_for_R4 (0.0.1-snapshot-2) (required to `http://hl7.org/fhir/5.0/ValueSet/R5-country-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
476. Extension.extension:sourceMaterial.url
Control	1..1
Fixed Value	`sourceMaterial`
478. Extension.url
Control	1..1
Fixed Value	`http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition`

Guidance on how to interpret the contents of this table can be foundhere

0. Extension
Definition	This cross-version extension represents SubstanceDefinition from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Optional Extension Element - found in all resources.
Short	The detailed description of a substance, typically at a level beyond what is used for prescribingOptional Extensions Element
Control	0..* This element is affected by the following invariants: ele-1
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
2. Extension.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
4. Extension.extension:version
Slice Name	version
Definition	This cross-version extension represents SubstanceDefinition.version from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A business level version identifier of the substanceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
6. Extension.extension:version.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`version`
8. Extension.extension:version.value[x]
Definition	This cross-version extension represents SubstanceDefinition.version from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	A business level version identifier of the substanceValue of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
10. Extension.extension:status
Slice Name	status
Definition	This cross-version extension represents SubstanceDefinition.status from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Status of substance within the catalogue e.g. active, retiredAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
12. Extension.extension:status.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`status`
14. Extension.extension:status.value[x]
Definition	This cross-version extension represents SubstanceDefinition.status from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Status of substance within the catalogue e.g. active, retiredValue of extension
Control	0..1
Binding	The codes SHOULD be taken from For codes, see R5_publication_status_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-publication-status-for-R4\|0.0.1-snapshot-2`) The lifecycle status of an artifact.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
16. Extension.extension:classification
Slice Name	classification
Definition	A high level categorization, e.g. polymer or nucleic acid, or food, chemical, biological, or a lower level such as the general types of polymer (linear or branch chain) or type of impurity (process related or contaminant).
Short	A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurityAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
18. Extension.extension:classification.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`classification`
20. Extension.extension:classification.value[x]
Definition	A high level categorization, e.g. polymer or nucleic acid, or food, chemical, biological, or a lower level such as the general types of polymer (linear or branch chain) or type of impurity (process related or contaminant). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurityValue of extension
Control	0..1
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
22. Extension.extension:domain
Slice Name	domain
Definition	This cross-version extension represents SubstanceDefinition.domain from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If the substance applies to human or veterinary useAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
24. Extension.extension:domain.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`domain`
26. Extension.extension:domain.value[x]
Definition	This cross-version extension represents SubstanceDefinition.domain from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	If the substance applies to human or veterinary useValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_medicinal_product_domain_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-medicinal-product-domain-for-R4\|0.0.1-snapshot-2`) Applicable domain for this product (e.g. human, veterinary).
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
28. Extension.extension:grade
Slice Name	grade
Definition	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, Ph. Eur, JP, BP, Company Standard).
Short	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP)Additional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
30. Extension.extension:grade.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`grade`
32. Extension.extension:grade.value[x]
Definition	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, Ph. Eur, JP, BP, Company Standard). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP)Value of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_grade_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-grade-for-R4\|0.0.1-snapshot-2`) The quality standard, established benchmark, to which a substance complies
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
34. Extension.extension:description
Slice Name	description
Definition	This cross-version extension represents SubstanceDefinition.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual description of the substanceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
36. Extension.extension:description.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`description`
38. Extension.extension:description.value[x]
Definition	This cross-version extension represents SubstanceDefinition.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Textual description of the substanceValue of extension
Control	0..1
Type	markdown, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
40. Extension.extension:informationSource
Slice Name	informationSource
Definition	This cross-version extension represents SubstanceDefinition.informationSource from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literatureAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
42. Extension.extension:informationSource.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`informationSource`
44. Extension.extension:informationSource.value[x]
Definition	This cross-version extension represents SubstanceDefinition.informationSource from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Supporting literatureValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
46. Extension.extension:note
Slice Name	note
Definition	This cross-version extension represents SubstanceDefinition.note from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual comment about the substance's catalogue or registry recordAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
48. Extension.extension:note.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`note`
50. Extension.extension:note.value[x]
Definition	This cross-version extension represents SubstanceDefinition.note from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Textual comment about the substance's catalogue or registry recordValue of extension
Control	0..1
Type	Annotation, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
52. Extension.extension:manufacturer
Slice Name	manufacturer
Definition	The entity that creates, makes, produces or fabricates the substance. This is a set of potential manufacturers but is not necessarily comprehensive.
Short	The entity that creates, makes, produces or fabricates the substanceAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
54. Extension.extension:manufacturer.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`manufacturer`
56. Extension.extension:manufacturer.value[x]
Definition	The entity that creates, makes, produces or fabricates the substance. This is a set of potential manufacturers but is not necessarily comprehensive. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The entity that creates, makes, produces or fabricates the substanceValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
58. Extension.extension:supplier
Slice Name	supplier
Definition	An entity that is the source for the substance. It may be different from the manufacturer. Supplier is synonymous to a distributor.
Short	An entity that is the source for the substance. It may be different from the manufacturerAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
60. Extension.extension:supplier.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`supplier`
62. Extension.extension:supplier.value[x]
Definition	An entity that is the source for the substance. It may be different from the manufacturer. Supplier is synonymous to a distributor. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	An entity that is the source for the substance. It may be different from the manufacturerValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
64. Extension.extension:moiety
Slice Name	moiety
Definition	This cross-version extension represents SubstanceDefinition.moiety from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Moiety, for structural modificationsAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
66. Extension.extension:moiety.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
68. Extension.extension:moiety.extension:role
Slice Name	role
Definition	This cross-version extension represents SubstanceDefinition.moiety.role from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Role that the moiety is playingAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
70. Extension.extension:moiety.extension:role.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`role`
72. Extension.extension:moiety.extension:role.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.role from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Role that the moiety is playingValue of extension
Control	0..1
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
74. Extension.extension:moiety.extension:identifier
Slice Name	identifier
Definition	This cross-version extension represents SubstanceDefinition.moiety.identifier from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Identifier by which this moiety substance is knownAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
76. Extension.extension:moiety.extension:identifier.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`identifier`
78. Extension.extension:moiety.extension:identifier.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.identifier from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Identifier by which this moiety substance is knownValue of extension
Control	0..1
Type	Identifier, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
80. Extension.extension:moiety.extension:name
Slice Name	name
Definition	This cross-version extension represents SubstanceDefinition.moiety.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual name for this moiety substanceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
82. Extension.extension:moiety.extension:name.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`name`
84. Extension.extension:moiety.extension:name.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Textual name for this moiety substanceValue of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
86. Extension.extension:moiety.extension:stereochemistry
Slice Name	stereochemistry
Definition	This cross-version extension represents SubstanceDefinition.moiety.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry typeAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
88. Extension.extension:moiety.extension:stereochemistry.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`stereochemistry`
90. Extension.extension:moiety.extension:stereochemistry.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Stereochemistry typeValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_stereochemistry_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-stereochemistry-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
92. Extension.extension:moiety.extension:opticalActivity
Slice Name	opticalActivity
Definition	This cross-version extension represents SubstanceDefinition.moiety.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity typeAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
94. Extension.extension:moiety.extension:opticalActivity.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`opticalActivity`
96. Extension.extension:moiety.extension:opticalActivity.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Optical activity typeValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_optical_activity_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-optical-activity-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
98. Extension.extension:moiety.extension:molecularFormula
Slice Name	molecularFormula
Definition	Molecular formula for this moiety of this substance, typically using the Hill system.
Short	Molecular formula for this moiety (e.g. with the Hill system)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
100. Extension.extension:moiety.extension:molecularFormula.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularFormula`
102. Extension.extension:moiety.extension:molecularFormula.value[x]
Definition	Molecular formula for this moiety of this substance, typically using the Hill system. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Molecular formula for this moiety (e.g. with the Hill system)Value of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
104. Extension.extension:moiety.extension:amount[x]
Slice Name	amount[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.amount[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Quantitative value for this moietyAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
106. Extension.extension:moiety.extension:amount[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`amount[x]`
108. Extension.extension:moiety.extension:amount[x].value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.amount[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Quantitative value for this moietyValue of extension
Control	0..1
Type	Choice of: Quantity, string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
110. Extension.extension:moiety.extension:measurementType
Slice Name	measurementType
Definition	The measurement type of the quantitative value. In capturing the actual relative amounts of substances or molecular fragments it may be necessary to indicate whether the amount refers to, for example, a mole ratio or weight ratio.
Short	The measurement type of the quantitative valueAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
112. Extension.extension:moiety.extension:measurementType.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`measurementType`
114. Extension.extension:moiety.extension:measurementType.value[x]
Definition	The measurement type of the quantitative value. In capturing the actual relative amounts of substances or molecular fragments it may be necessary to indicate whether the amount refers to, for example, a mole ratio or weight ratio. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The measurement type of the quantitative valueValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_amount_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-amount-type-for-R4\|0.0.1-snapshot-2`) The relationship between two substance types.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
116. Extension.extension:moiety.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`moiety`
118. Extension.extension:characterization
Slice Name	characterization
Definition	This cross-version extension represents SubstanceDefinition.characterization from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General specifications for this substanceAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
120. Extension.extension:characterization.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
122. Extension.extension:characterization.extension:technique
Slice Name	technique
Definition	The method used to elucidate the characterization of the drug substance. Example: HPLC.
Short	The method used to find the characterization e.g. HPLCAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
124. Extension.extension:characterization.extension:technique.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`technique`
126. Extension.extension:characterization.extension:technique.value[x]
Definition	The method used to elucidate the characterization of the drug substance. Example: HPLC. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The method used to find the characterization e.g. HPLCValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_structure_technique_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-structure-technique-for-R4\|0.0.1-snapshot-2`) The method used to elucidate the characterization of the drug substance.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
128. Extension.extension:characterization.extension:form
Slice Name	form
Definition	This cross-version extension represents SubstanceDefinition.characterization.form from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt formAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
130. Extension.extension:characterization.extension:form.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`form`
132. Extension.extension:characterization.extension:form.value[x]
Definition	This cross-version extension represents SubstanceDefinition.characterization.form from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt formValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_form_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-form-for-R4\|0.0.1-snapshot-2`)
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
134. Extension.extension:characterization.extension:description
Slice Name	description
Definition	This cross-version extension represents SubstanceDefinition.characterization.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The description or justification in support of the interpretation of the data fileAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
136. Extension.extension:characterization.extension:description.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`description`
138. Extension.extension:characterization.extension:description.value[x]
Definition	This cross-version extension represents SubstanceDefinition.characterization.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The description or justification in support of the interpretation of the data fileValue of extension
Control	0..1
Type	markdown, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
140. Extension.extension:characterization.extension:file
Slice Name	file
Definition	This cross-version extension represents SubstanceDefinition.characterization.file from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysisAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
142. Extension.extension:characterization.extension:file.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`file`
144. Extension.extension:characterization.extension:file.value[x]
Definition	This cross-version extension represents SubstanceDefinition.characterization.file from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysisValue of extension
Control	0..1
Type	Attachment, date, Meta, Address, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
146. Extension.extension:characterization.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`characterization`
148. Extension.extension:property
Slice Name	property
Definition	This cross-version extension represents SubstanceDefinition.property from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General specifications for this substanceAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
150. Extension.extension:property.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	10..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
152. Extension.extension:property.extension:type
Slice Name	type
Definition	This cross-version extension represents SubstanceDefinition.property.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A code expressing the type of propertyAdditional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
154. Extension.extension:property.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
156. Extension.extension:property.extension:type.value[x]
Definition	This cross-version extension represents SubstanceDefinition.property.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	A code expressing the type of propertyValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_product_characteristic_codes_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-product-characteristic-codes-for-R4\|0.0.1-snapshot-2`) This value set includes all observable entity codes from SNOMED CT - provided as an exemplar value set.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
158. Extension.extension:property.extension:value[x]
Slice Name	value[x]
Definition	This cross-version extension represents SubstanceDefinition.property.value[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A value for the propertyAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
160. Extension.extension:property.extension:value[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`value[x]`
162. Extension.extension:property.extension:value[x].value[x]
Definition	This cross-version extension represents SubstanceDefinition.property.value[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	A value for the propertyValue of extension
Control	0..1
Type	Choice of: CodeableConcept, Quantity, date, boolean, Attachment, Meta, Address, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
164. Extension.extension:property.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`property`
166. Extension.extension:referenceInformation
Slice Name	referenceInformation
Definition	This cross-version extension represents SubstanceDefinition.referenceInformation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General information detailing this substanceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
168. Extension.extension:referenceInformation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`referenceInformation`
170. Extension.extension:referenceInformation.value[x]
Definition	This cross-version extension represents SubstanceDefinition.referenceInformation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	General information detailing this substanceValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
172. Extension.extension:molecularWeight
Slice Name	molecularWeight
Definition	The average mass of a molecule of a compound compared to 1/12 the mass of carbon 12 and calculated as the sum of the atomic weights of the constituent atoms.
Short	The average mass of a molecule of a compoundAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
174. Extension.extension:molecularWeight.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	10..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
176. Extension.extension:molecularWeight.extension:method
Slice Name	method
Definition	The method by which the molecular weight was determined.
Short	The method by which the weight was determinedAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
178. Extension.extension:molecularWeight.extension:method.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`method`
180. Extension.extension:molecularWeight.extension:method.value[x]
Definition	The method by which the molecular weight was determined. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The method by which the weight was determinedValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_weight_method_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-weight-method-for-R4\|0.0.1-snapshot-2`) The method by which the substance weight was measured.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
182. Extension.extension:molecularWeight.extension:type
Slice Name	type
Definition	Type of molecular weight such as exact, average (also known as. number average), weight average.
Short	Type of molecular weight e.g. exact, average, weight averageAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
184. Extension.extension:molecularWeight.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
186. Extension.extension:molecularWeight.extension:type.value[x]
Definition	Type of molecular weight such as exact, average (also known as. number average), weight average. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Type of molecular weight e.g. exact, average, weight averageValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_weight_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-weight-type-for-R4\|0.0.1-snapshot-2`) The type of substance weight measurement.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
188. Extension.extension:molecularWeight.extension:amount
Slice Name	amount
Definition	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field.
Short	Used to capture quantitative values for a variety of elementsAdditional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
190. Extension.extension:molecularWeight.extension:amount.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`amount`
192. Extension.extension:molecularWeight.extension:amount.value[x]
Definition	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Used to capture quantitative values for a variety of elementsValue of extension
Control	0..1
Type	Quantity, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
194. Extension.extension:molecularWeight.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularWeight`
196. Extension.extension:structure
Slice Name	structure
Definition	This cross-version extension represents SubstanceDefinition.structure from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Structural informationAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
198. Extension.extension:structure.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
200. Extension.extension:structure.extension:stereochemistry
Slice Name	stereochemistry
Definition	This cross-version extension represents SubstanceDefinition.structure.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry typeAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
202. Extension.extension:structure.extension:stereochemistry.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`stereochemistry`
204. Extension.extension:structure.extension:stereochemistry.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Stereochemistry typeValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_stereochemistry_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-stereochemistry-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
206. Extension.extension:structure.extension:opticalActivity
Slice Name	opticalActivity
Definition	This cross-version extension represents SubstanceDefinition.structure.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity typeAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
208. Extension.extension:structure.extension:opticalActivity.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`opticalActivity`
210. Extension.extension:structure.extension:opticalActivity.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Optical activity typeValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_optical_activity_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-optical-activity-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
212. Extension.extension:structure.extension:molecularFormula
Slice Name	molecularFormula
Definition	This cross-version extension represents SubstanceDefinition.structure.molecularFormula from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An expression which states the number and type of atoms present in a molecule of a substanceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
214. Extension.extension:structure.extension:molecularFormula.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularFormula`
216. Extension.extension:structure.extension:molecularFormula.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.molecularFormula from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	An expression which states the number and type of atoms present in a molecule of a substanceValue of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
218. Extension.extension:structure.extension:molecularFormulaByMoiety
Slice Name	molecularFormulaByMoiety
Definition	Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical, each moiety separated by a dot.
Short	Specified per moiety according to the Hill systemAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
220. Extension.extension:structure.extension:molecularFormulaByMoiety.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularFormulaByMoiety`
222. Extension.extension:structure.extension:molecularFormulaByMoiety.value[x]
Definition	Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical, each moiety separated by a dot. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Specified per moiety according to the Hill systemValue of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
224. Extension.extension:structure.extension:molecularWeight
Slice Name	molecularWeight
Definition	The molecular weight or weight range (for proteins, polymers or nucleic acids).
Short	The molecular weight or weight rangeAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
226. Extension.extension:structure.extension:molecularWeight.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
228. Extension.extension:structure.extension:molecularWeight.extension:_datatype
Slice Name	_datatype
Definition	Data type name for SubstanceDefinition.structure.molecularWeight from FHIR R5
Short	Data type name for SubstanceDefinition.structure.molecularWeight from FHIR R5
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
230. Extension.extension:structure.extension:molecularWeight.extension:_datatype.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..0*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
232. Extension.extension:structure.extension:molecularWeight.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
234. Extension.extension:structure.extension:molecularWeight.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: SubstanceDefinition.molecularWeight
Control	10..1 This element is affected by the following invariants: ext-1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`SubstanceDefinition.molecularWeight`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
236. Extension.extension:structure.extension:molecularWeight.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularWeight`
238. Extension.extension:structure.extension:technique
Slice Name	technique
Definition	The method used to elucidate the structure of the drug substance. Examples: X-ray, NMR, Peptide mapping, Ligand binding assay.
Short	The method used to find the structure e.g. X-ray, NMRAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
240. Extension.extension:structure.extension:technique.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`technique`
242. Extension.extension:structure.extension:technique.value[x]
Definition	The method used to elucidate the structure of the drug substance. Examples: X-ray, NMR, Peptide mapping, Ligand binding assay. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The method used to find the structure e.g. X-ray, NMRValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_structure_technique_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-structure-technique-for-R4\|0.0.1-snapshot-2`) The method used to elucidate the structure of the drug substance.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
244. Extension.extension:structure.extension:sourceDocument
Slice Name	sourceDocument
Definition	The source of information about the structure.
Short	Source of information for the structureAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
246. Extension.extension:structure.extension:sourceDocument.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`sourceDocument`
248. Extension.extension:structure.extension:sourceDocument.value[x]
Definition	The source of information about the structure. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Source of information for the structureValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
250. Extension.extension:structure.extension:representation
Slice Name	representation
Definition	This cross-version extension represents SubstanceDefinition.structure.representation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A depiction of the structure of the substanceAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
252. Extension.extension:structure.extension:representation.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
254. Extension.extension:structure.extension:representation.extension:type
Slice Name	type
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The kind of structural representation (e.g. full, partial)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
256. Extension.extension:structure.extension:representation.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
258. Extension.extension:structure.extension:representation.extension:type.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The kind of structural representation (e.g. full, partial)Value of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_representation_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-representation-type-for-R4\|0.0.1-snapshot-2`) A format of a substance representation.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
260. Extension.extension:structure.extension:representation.extension:representation
Slice Name	representation
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.representation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The structural representation as a text string in a standard formatAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
262. Extension.extension:structure.extension:representation.extension:representation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`representation`
264. Extension.extension:structure.extension:representation.extension:representation.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.representation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The structural representation as a text string in a standard formatValue of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
266. Extension.extension:structure.extension:representation.extension:format
Slice Name	format
Definition	The format of the representation e.g. InChI, SMILES, MOLFILE, CDX, SDF, PDB, mmCIF. The logical content type rather than the physical file format of a document.
Short	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
268. Extension.extension:structure.extension:representation.extension:format.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`format`
270. Extension.extension:structure.extension:representation.extension:format.value[x]
Definition	The format of the representation e.g. InChI, SMILES, MOLFILE, CDX, SDF, PDB, mmCIF. The logical content type rather than the physical file format of a document. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format)Value of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_representation_format_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-representation-format-for-R4\|0.0.1-snapshot-2`) A format of a substance representation.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
272. Extension.extension:structure.extension:representation.extension:document
Slice Name	document
Definition	An attached file with the structural representation e.g. a molecular structure graphic of the substance, a JCAMP or AnIML file.
Short	An attachment with the structural representation e.g. a structure graphic or AnIML fileAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
274. Extension.extension:structure.extension:representation.extension:document.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`document`
276. Extension.extension:structure.extension:representation.extension:document.value[x]
Definition	An attached file with the structural representation e.g. a molecular structure graphic of the substance, a JCAMP or AnIML file. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	An attachment with the structural representation e.g. a structure graphic or AnIML fileValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
278. Extension.extension:structure.extension:representation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`representation`
280. Extension.extension:structure.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`structure`
282. Extension.extension:name
Slice Name	name
Definition	This cross-version extension represents SubstanceDefinition.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Names applicable to this substanceAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
284. Extension.extension:name.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	10..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
286. Extension.extension:name.extension:name
Slice Name	name
Definition	This cross-version extension represents SubstanceDefinition.name.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The actual nameAdditional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
288. Extension.extension:name.extension:name.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`name`
290. Extension.extension:name.extension:name.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The actual nameValue of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
292. Extension.extension:name.extension:type
Slice Name	type
Definition	Name type, for example 'systematic', 'scientific, 'brand'.
Short	Name type e.g. 'systematic', 'scientific, 'brand'Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
294. Extension.extension:name.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
296. Extension.extension:name.extension:type.value[x]
Definition	Name type, for example 'systematic', 'scientific, 'brand'. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Name type e.g. 'systematic', 'scientific, 'brand'Value of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_name_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-name-type-for-R4\|0.0.1-snapshot-2`) The type of a name given to a substance.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
298. Extension.extension:name.extension:status
Slice Name	status
Definition	The status of the name, for example 'current', 'proposed'.
Short	The status of the name e.g. 'current', 'proposed'Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
300. Extension.extension:name.extension:status.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`status`
302. Extension.extension:name.extension:status.value[x]
Definition	The status of the name, for example 'current', 'proposed'. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The status of the name e.g. 'current', 'proposed'Value of extension
Control	0..1
Binding	The codes SHOULD be taken from For codes, see R5_publication_status_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-publication-status-for-R4\|0.0.1-snapshot-2`) The lifecycle status of an artifact.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
304. Extension.extension:name.extension:preferred
Slice Name	preferred
Definition	This cross-version extension represents SubstanceDefinition.name.preferred from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If this is the preferred name for this substanceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
306. Extension.extension:name.extension:preferred.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`preferred`
308. Extension.extension:name.extension:preferred.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.preferred from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	If this is the preferred name for this substanceValue of extension
Control	0..1
Type	boolean, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
310. Extension.extension:name.extension:language
Slice Name	language
Definition	This cross-version extension represents SubstanceDefinition.name.language from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Human language that the name is written inAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
312. Extension.extension:name.extension:language.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`language`
314. Extension.extension:name.extension:language.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.language from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Human language that the name is written inValue of extension
Control	0..1
Binding	The codes SHALL be taken from For codes, see AllLanguages (required to `http://hl7.org/fhir/ValueSet/all-languages\|4.0.1`) IETF language tag for a human language
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
316. Extension.extension:name.extension:domain
Slice Name	domain
Definition	The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive.
Short	The use context of this name e.g. as an active ingredient or as a food colour additiveAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
318. Extension.extension:name.extension:domain.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`domain`
320. Extension.extension:name.extension:domain.value[x]
Definition	The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The use context of this name e.g. as an active ingredient or as a food colour additiveValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_name_domain_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-name-domain-for-R4\|0.0.1-snapshot-2`) The use context of a substance name for example if there is a different name when used as a drug active ingredient as opposed to a food colour additive.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
322. Extension.extension:name.extension:jurisdiction
Slice Name	jurisdiction
Definition	This cross-version extension represents SubstanceDefinition.name.jurisdiction from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The jurisdiction where this name appliesAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
324. Extension.extension:name.extension:jurisdiction.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`jurisdiction`
326. Extension.extension:name.extension:jurisdiction.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.jurisdiction from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The jurisdiction where this name appliesValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_jurisdiction_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-jurisdiction-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
328. Extension.extension:name.extension:synonym
Slice Name	synonym
Definition	This cross-version extension represents SubstanceDefinition.name.synonym from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A synonym of this particular name, by which the substance is also knownAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
330. Extension.extension:name.extension:synonym.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
332. Extension.extension:name.extension:synonym.extension:_datatype
Slice Name	_datatype
Definition	Data type name for SubstanceDefinition.name.synonym from FHIR R5
Short	Data type name for SubstanceDefinition.name.synonym from FHIR R5
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
334. Extension.extension:name.extension:synonym.extension:_datatype.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..0*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
336. Extension.extension:name.extension:synonym.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
338. Extension.extension:name.extension:synonym.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: SubstanceDefinition.name
Control	10..1 This element is affected by the following invariants: ext-1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`SubstanceDefinition.name`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
340. Extension.extension:name.extension:synonym.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`synonym`
342. Extension.extension:name.extension:translation
Slice Name	translation
Definition	This cross-version extension represents SubstanceDefinition.name.translation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A translation for this name into another human languageAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
344. Extension.extension:name.extension:translation.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
346. Extension.extension:name.extension:translation.extension:_datatype
Slice Name	_datatype
Definition	Data type name for SubstanceDefinition.name.translation from FHIR R5
Short	Data type name for SubstanceDefinition.name.translation from FHIR R5
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
348. Extension.extension:name.extension:translation.extension:_datatype.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..0*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
350. Extension.extension:name.extension:translation.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
352. Extension.extension:name.extension:translation.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: SubstanceDefinition.name
Control	10..1 This element is affected by the following invariants: ext-1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`SubstanceDefinition.name`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
354. Extension.extension:name.extension:translation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`translation`
356. Extension.extension:name.extension:official
Slice Name	official
Definition	This cross-version extension represents SubstanceDefinition.name.official from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Details of the official nature of this nameAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
358. Extension.extension:name.extension:official.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
360. Extension.extension:name.extension:official.extension:authority
Slice Name	authority
Definition	This cross-version extension represents SubstanceDefinition.name.official.authority from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Which authority uses this official nameAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
362. Extension.extension:name.extension:official.extension:authority.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`authority`
364. Extension.extension:name.extension:official.extension:authority.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.official.authority from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Which authority uses this official nameValue of extension
Control	0..1
Binding	The codes SHOULD be taken from For codes, see R5_substance_name_authority_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-name-authority-for-R4\|0.0.1-snapshot-2`) An authority that officates substance names.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
366. Extension.extension:name.extension:official.extension:status
Slice Name	status
Definition	The status of the official name, for example 'draft', 'active', 'retired'.
Short	The status of the official name, for example 'draft', 'active'Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
368. Extension.extension:name.extension:official.extension:status.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`status`
370. Extension.extension:name.extension:official.extension:status.value[x]
Definition	The status of the official name, for example 'draft', 'active', 'retired'. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The status of the official name, for example 'draft', 'active'Value of extension
Control	0..1
Binding	The codes SHOULD be taken from For codes, see R5_publication_status_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-publication-status-for-R4\|0.0.1-snapshot-2`) The lifecycle status of an artifact.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
372. Extension.extension:name.extension:official.extension:date
Slice Name	date
Definition	Date of the official name change.
Short	Date of official name changeAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
374. Extension.extension:name.extension:official.extension:date.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`date`
376. Extension.extension:name.extension:official.extension:date.value[x]
Definition	Date of the official name change. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Date of official name changeValue of extension
Control	0..1
Type	dateTime, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
378. Extension.extension:name.extension:official.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`official`
380. Extension.extension:name.extension:source
Slice Name	source
Definition	This cross-version extension represents SubstanceDefinition.name.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literatureAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
382. Extension.extension:name.extension:source.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`source`
384. Extension.extension:name.extension:source.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Supporting literatureValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
386. Extension.extension:name.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`name`
388. Extension.extension:relationship
Slice Name	relationship
Definition	A link between this substance and another, with details of the relationship.
Short	A link between this substance and anotherAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
390. Extension.extension:relationship.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	10..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
392. Extension.extension:relationship.extension:substanceDefinition[x]
Slice Name	substanceDefinition[x]
Definition	A pointer to another substance, as a resource or just a representational code.
Short	A pointer to another substance, as a resource or a representational codeAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
394. Extension.extension:relationship.extension:substanceDefinition[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`substanceDefinition[x]`
396. Extension.extension:relationship.extension:substanceDefinition[x].value[x]
Definition	A pointer to another substance, as a resource or just a representational code. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	A pointer to another substance, as a resource or a representational codeValue of extension
Control	0..1
Type	Choice of: Reference, CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
398. Extension.extension:relationship.extension:type
Slice Name	type
Definition	For example "salt to parent", "active moiety", "starting material", "polymorph", "impurity of".
Short	For example "salt to parent", "active moiety"Additional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
400. Extension.extension:relationship.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
402. Extension.extension:relationship.extension:type.value[x]
Definition	For example "salt to parent", "active moiety", "starting material", "polymorph", "impurity of". Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	For example "salt to parent", "active moiety"Value of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_relationship_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-relationship-type-for-R4\|0.0.1-snapshot-2`) The relationship between two substance types.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
404. Extension.extension:relationship.extension:isDefining
Slice Name	isDefining
Definition	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible substance relationships.
Short	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationshipsAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
406. Extension.extension:relationship.extension:isDefining.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`isDefining`
408. Extension.extension:relationship.extension:isDefining.value[x]
Definition	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible substance relationships. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationshipsValue of extension
Control	0..1
Type	boolean, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
410. Extension.extension:relationship.extension:amount[x]
Slice Name	amount[x]
Definition	A numeric factor for the relationship, for instance to express that the salt of a substance has some percentage of the active substance in relation to some other.
Short	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some otherAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
412. Extension.extension:relationship.extension:amount[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`amount[x]`
414. Extension.extension:relationship.extension:amount[x].value[x]
Definition	A numeric factor for the relationship, for instance to express that the salt of a substance has some percentage of the active substance in relation to some other. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some otherValue of extension
Control	0..1
Type	Choice of: Quantity, Ratio, string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
416. Extension.extension:relationship.extension:ratioHighLimitAmount
Slice Name	ratioHighLimitAmount
Definition	This cross-version extension represents SubstanceDefinition.relationship.ratioHighLimitAmount from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	For use when the numeric has an uncertain rangeAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
418. Extension.extension:relationship.extension:ratioHighLimitAmount.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`ratioHighLimitAmount`
420. Extension.extension:relationship.extension:ratioHighLimitAmount.value[x]
Definition	This cross-version extension represents SubstanceDefinition.relationship.ratioHighLimitAmount from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	For use when the numeric has an uncertain rangeValue of extension
Control	0..1
Type	Ratio, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
422. Extension.extension:relationship.extension:comparator
Slice Name	comparator
Definition	This cross-version extension represents SubstanceDefinition.relationship.comparator from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An operator for the amount, for example "average", "approximately", "less than"Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
424. Extension.extension:relationship.extension:comparator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`comparator`
426. Extension.extension:relationship.extension:comparator.value[x]
Definition	This cross-version extension represents SubstanceDefinition.relationship.comparator from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	An operator for the amount, for example "average", "approximately", "less than"Value of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_amount_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-amount-type-for-R4\|0.0.1-snapshot-2`) The relationship between two substance types.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
428. Extension.extension:relationship.extension:source
Slice Name	source
Definition	This cross-version extension represents SubstanceDefinition.relationship.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literatureAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
430. Extension.extension:relationship.extension:source.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`source`
432. Extension.extension:relationship.extension:source.value[x]
Definition	This cross-version extension represents SubstanceDefinition.relationship.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Supporting literatureValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
434. Extension.extension:relationship.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`relationship`
436. Extension.extension:nucleicAcid
Slice Name	nucleicAcid
Definition	This cross-version extension represents SubstanceDefinition.nucleicAcid from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to nucleic acidsAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
438. Extension.extension:nucleicAcid.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`nucleicAcid`
440. Extension.extension:nucleicAcid.value[x]
Definition	This cross-version extension represents SubstanceDefinition.nucleicAcid from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Data items specific to nucleic acidsValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
442. Extension.extension:polymer
Slice Name	polymer
Definition	This cross-version extension represents SubstanceDefinition.polymer from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to polymersAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
444. Extension.extension:polymer.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`polymer`
446. Extension.extension:polymer.value[x]
Definition	This cross-version extension represents SubstanceDefinition.polymer from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Data items specific to polymersValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
448. Extension.extension:protein
Slice Name	protein
Definition	This cross-version extension represents SubstanceDefinition.protein from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to proteinsAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
450. Extension.extension:protein.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`protein`
452. Extension.extension:protein.value[x]
Definition	This cross-version extension represents SubstanceDefinition.protein from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Data items specific to proteinsValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
454. Extension.extension:sourceMaterial
Slice Name	sourceMaterial
Definition	Material or taxonomic/anatomical source for the substance.
Short	Material or taxonomic/anatomical sourceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
456. Extension.extension:sourceMaterial.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
458. Extension.extension:sourceMaterial.extension:type
Slice Name	type
Definition	A classification that provides the origin of the raw material. Example: cat hair would be an Animal source type.
Short	Classification of the origin of the raw material. e.g. cat hair is an Animal source typeAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
460. Extension.extension:sourceMaterial.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
462. Extension.extension:sourceMaterial.extension:type.value[x]
Definition	A classification that provides the origin of the raw material. Example: cat hair would be an Animal source type. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Classification of the origin of the raw material. e.g. cat hair is an Animal source typeValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_source_material_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-type-for-R4\|0.0.1-snapshot-2`) A classification that provides the origin of the substance raw material.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
464. Extension.extension:sourceMaterial.extension:genus
Slice Name	genus
Definition	The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
Short	The genus of an organism e.g. the Latin epithet of the plant/animal scientific nameAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
466. Extension.extension:sourceMaterial.extension:genus.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`genus`
468. Extension.extension:sourceMaterial.extension:genus.value[x]
Definition	The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The genus of an organism e.g. the Latin epithet of the plant/animal scientific nameValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_source_material_genus_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-genus-for-R4\|0.0.1-snapshot-2`) The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
470. Extension.extension:sourceMaterial.extension:species
Slice Name	species
Definition	The species of an organism, typically referring to the Latin epithet of the species of the plant/animal.
Short	The species of an organism e.g. the Latin epithet of the species of the plant/animalAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
472. Extension.extension:sourceMaterial.extension:species.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`species`
474. Extension.extension:sourceMaterial.extension:species.value[x]
Definition	The species of an organism, typically referring to the Latin epithet of the species of the plant/animal. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The species of an organism e.g. the Latin epithet of the species of the plant/animalValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_source_material_species_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-species-for-R4\|0.0.1-snapshot-2`) A species of origin a substance raw material.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
476. Extension.extension:sourceMaterial.extension:part
Slice Name	part
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.part from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An anatomical origin of the source material within an organismAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
478. Extension.extension:sourceMaterial.extension:part.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`part`
480. Extension.extension:sourceMaterial.extension:part.value[x]
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.part from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	An anatomical origin of the source material within an organismValue of extension
Control	0..1
Binding	For example codes, see For codes, see R5_substance_source_material_part_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-part-for-R4\|0.0.1-snapshot-2`) An anatomical origin of the source material within an organism.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
482. Extension.extension:sourceMaterial.extension:countryOfOrigin
Slice Name	countryOfOrigin
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.countryOfOrigin from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The country or countries where the material is harvestedAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
484. Extension.extension:sourceMaterial.extension:countryOfOrigin.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`countryOfOrigin`
486. Extension.extension:sourceMaterial.extension:countryOfOrigin.value[x]
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.countryOfOrigin from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The country or countries where the material is harvestedValue of extension
Control	0..1
Binding	The codes SHALL be taken from For codes, see R5_country_for_R4 (0.0.1-snapshot-2) (required to `http://hl7.org/fhir/5.0/ValueSet/R5-country-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
488. Extension.extension:sourceMaterial.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`sourceMaterial`
490. Extension.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition`

Guidance on how to interpret the contents of this table can be foundhere

0. Extension
Definition	This cross-version extension represents SubstanceDefinition from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The detailed description of a substance, typically at a level beyond what is used for prescribing
Control	0..* This element is affected by the following invariants: ele-1
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2. Extension.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4. Extension.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
6. Extension.extension:version
Slice Name	version
Definition	This cross-version extension represents SubstanceDefinition.version from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A business level version identifier of the substance
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
8. Extension.extension:version.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
10. Extension.extension:version.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
12. Extension.extension:version.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`version`
14. Extension.extension:version.value[x]
Definition	This cross-version extension represents SubstanceDefinition.version from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A business level version identifier of the substance
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
16. Extension.extension:status
Slice Name	status
Definition	This cross-version extension represents SubstanceDefinition.status from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Status of substance within the catalogue e.g. active, retired
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
18. Extension.extension:status.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
20. Extension.extension:status.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
22. Extension.extension:status.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`status`
24. Extension.extension:status.value[x]
Definition	This cross-version extension represents SubstanceDefinition.status from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Status of substance within the catalogue e.g. active, retired
Control	0..1
Binding	The codes SHOULD be taken from R5_publication_status_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-publication-status-for-R4\|0.0.1-snapshot-2`) The lifecycle status of an artifact.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
26. Extension.extension:classification
Slice Name	classification
Definition	A high level categorization, e.g. polymer or nucleic acid, or food, chemical, biological, or a lower level such as the general types of polymer (linear or branch chain) or type of impurity (process related or contaminant).
Short	A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
28. Extension.extension:classification.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
30. Extension.extension:classification.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
32. Extension.extension:classification.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`classification`
34. Extension.extension:classification.value[x]
Definition	A high level categorization, e.g. polymer or nucleic acid, or food, chemical, biological, or a lower level such as the general types of polymer (linear or branch chain) or type of impurity (process related or contaminant).
Short	A categorization, high level e.g. polymer or nucleic acid, or food, chemical, biological, or lower e.g. polymer linear or branch chain, or type of impurity
Control	0..1
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
36. Extension.extension:domain
Slice Name	domain
Definition	This cross-version extension represents SubstanceDefinition.domain from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If the substance applies to human or veterinary use
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
38. Extension.extension:domain.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
40. Extension.extension:domain.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
42. Extension.extension:domain.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`domain`
44. Extension.extension:domain.value[x]
Definition	This cross-version extension represents SubstanceDefinition.domain from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If the substance applies to human or veterinary use
Control	0..1
Binding	For example codes, see R5_medicinal_product_domain_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-medicinal-product-domain-for-R4\|0.0.1-snapshot-2`) Applicable domain for this product (e.g. human, veterinary).
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
46. Extension.extension:grade
Slice Name	grade
Definition	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, Ph. Eur, JP, BP, Company Standard).
Short	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP)
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
48. Extension.extension:grade.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
50. Extension.extension:grade.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
52. Extension.extension:grade.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`grade`
54. Extension.extension:grade.value[x]
Definition	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, Ph. Eur, JP, BP, Company Standard).
Short	The quality standard, established benchmark, to which substance complies (e.g. USP/NF, BP)
Control	0..1
Binding	For example codes, see R5_substance_grade_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-grade-for-R4\|0.0.1-snapshot-2`) The quality standard, established benchmark, to which a substance complies
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
56. Extension.extension:description
Slice Name	description
Definition	This cross-version extension represents SubstanceDefinition.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual description of the substance
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
58. Extension.extension:description.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
60. Extension.extension:description.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
62. Extension.extension:description.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`description`
64. Extension.extension:description.value[x]
Definition	This cross-version extension represents SubstanceDefinition.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual description of the substance
Control	0..1
Type	markdown
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
66. Extension.extension:informationSource
Slice Name	informationSource
Definition	This cross-version extension represents SubstanceDefinition.informationSource from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
68. Extension.extension:informationSource.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
70. Extension.extension:informationSource.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
72. Extension.extension:informationSource.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`informationSource`
74. Extension.extension:informationSource.value[x]
Definition	This cross-version extension represents SubstanceDefinition.informationSource from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
76. Extension.extension:note
Slice Name	note
Definition	This cross-version extension represents SubstanceDefinition.note from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual comment about the substance's catalogue or registry record
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
78. Extension.extension:note.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
80. Extension.extension:note.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
82. Extension.extension:note.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`note`
84. Extension.extension:note.value[x]
Definition	This cross-version extension represents SubstanceDefinition.note from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual comment about the substance's catalogue or registry record
Control	0..1
Type	Annotation
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
86. Extension.extension:manufacturer
Slice Name	manufacturer
Definition	The entity that creates, makes, produces or fabricates the substance. This is a set of potential manufacturers but is not necessarily comprehensive.
Short	The entity that creates, makes, produces or fabricates the substance
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
88. Extension.extension:manufacturer.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
90. Extension.extension:manufacturer.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
92. Extension.extension:manufacturer.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`manufacturer`
94. Extension.extension:manufacturer.value[x]
Definition	The entity that creates, makes, produces or fabricates the substance. This is a set of potential manufacturers but is not necessarily comprehensive.
Short	The entity that creates, makes, produces or fabricates the substance
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
96. Extension.extension:supplier
Slice Name	supplier
Definition	An entity that is the source for the substance. It may be different from the manufacturer. Supplier is synonymous to a distributor.
Short	An entity that is the source for the substance. It may be different from the manufacturer
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
98. Extension.extension:supplier.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
100. Extension.extension:supplier.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
102. Extension.extension:supplier.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`supplier`
104. Extension.extension:supplier.value[x]
Definition	An entity that is the source for the substance. It may be different from the manufacturer. Supplier is synonymous to a distributor.
Short	An entity that is the source for the substance. It may be different from the manufacturer
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
106. Extension.extension:moiety
Slice Name	moiety
Definition	This cross-version extension represents SubstanceDefinition.moiety from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Moiety, for structural modifications
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
108. Extension.extension:moiety.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
110. Extension.extension:moiety.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
112. Extension.extension:moiety.extension:role
Slice Name	role
Definition	This cross-version extension represents SubstanceDefinition.moiety.role from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Role that the moiety is playing
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
114. Extension.extension:moiety.extension:role.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
116. Extension.extension:moiety.extension:role.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
118. Extension.extension:moiety.extension:role.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`role`
120. Extension.extension:moiety.extension:role.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.role from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Role that the moiety is playing
Control	0..1
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
122. Extension.extension:moiety.extension:identifier
Slice Name	identifier
Definition	This cross-version extension represents SubstanceDefinition.moiety.identifier from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Identifier by which this moiety substance is known
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
124. Extension.extension:moiety.extension:identifier.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
126. Extension.extension:moiety.extension:identifier.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
128. Extension.extension:moiety.extension:identifier.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`identifier`
130. Extension.extension:moiety.extension:identifier.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.identifier from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Identifier by which this moiety substance is known
Control	0..1
Type	Identifier
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
132. Extension.extension:moiety.extension:name
Slice Name	name
Definition	This cross-version extension represents SubstanceDefinition.moiety.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual name for this moiety substance
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
134. Extension.extension:moiety.extension:name.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
136. Extension.extension:moiety.extension:name.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
138. Extension.extension:moiety.extension:name.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`name`
140. Extension.extension:moiety.extension:name.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Textual name for this moiety substance
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
142. Extension.extension:moiety.extension:stereochemistry
Slice Name	stereochemistry
Definition	This cross-version extension represents SubstanceDefinition.moiety.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry type
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
144. Extension.extension:moiety.extension:stereochemistry.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
146. Extension.extension:moiety.extension:stereochemistry.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
148. Extension.extension:moiety.extension:stereochemistry.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`stereochemistry`
150. Extension.extension:moiety.extension:stereochemistry.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry type
Control	0..1
Binding	For example codes, see R5_substance_stereochemistry_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-stereochemistry-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
152. Extension.extension:moiety.extension:opticalActivity
Slice Name	opticalActivity
Definition	This cross-version extension represents SubstanceDefinition.moiety.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity type
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
154. Extension.extension:moiety.extension:opticalActivity.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
156. Extension.extension:moiety.extension:opticalActivity.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
158. Extension.extension:moiety.extension:opticalActivity.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`opticalActivity`
160. Extension.extension:moiety.extension:opticalActivity.value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity type
Control	0..1
Binding	For example codes, see R5_substance_optical_activity_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-optical-activity-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
162. Extension.extension:moiety.extension:molecularFormula
Slice Name	molecularFormula
Definition	Molecular formula for this moiety of this substance, typically using the Hill system.
Short	Molecular formula for this moiety (e.g. with the Hill system)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
164. Extension.extension:moiety.extension:molecularFormula.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
166. Extension.extension:moiety.extension:molecularFormula.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
168. Extension.extension:moiety.extension:molecularFormula.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularFormula`
170. Extension.extension:moiety.extension:molecularFormula.value[x]
Definition	Molecular formula for this moiety of this substance, typically using the Hill system.
Short	Molecular formula for this moiety (e.g. with the Hill system)
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
172. Extension.extension:moiety.extension:amount[x]
Slice Name	amount[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.amount[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Quantitative value for this moiety
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
174. Extension.extension:moiety.extension:amount[x].id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
176. Extension.extension:moiety.extension:amount[x].extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
178. Extension.extension:moiety.extension:amount[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`amount[x]`
180. Extension.extension:moiety.extension:amount[x].value[x]
Definition	This cross-version extension represents SubstanceDefinition.moiety.amount[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Quantitative value for this moiety
Control	0..1
Type	Choice of: Quantity, string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
182. Extension.extension:moiety.extension:measurementType
Slice Name	measurementType
Definition	The measurement type of the quantitative value. In capturing the actual relative amounts of substances or molecular fragments it may be necessary to indicate whether the amount refers to, for example, a mole ratio or weight ratio.
Short	The measurement type of the quantitative value
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
184. Extension.extension:moiety.extension:measurementType.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
186. Extension.extension:moiety.extension:measurementType.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
188. Extension.extension:moiety.extension:measurementType.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`measurementType`
190. Extension.extension:moiety.extension:measurementType.value[x]
Definition	The measurement type of the quantitative value. In capturing the actual relative amounts of substances or molecular fragments it may be necessary to indicate whether the amount refers to, for example, a mole ratio or weight ratio.
Short	The measurement type of the quantitative value
Control	0..1
Binding	For example codes, see R5_substance_amount_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-amount-type-for-R4\|0.0.1-snapshot-2`) The relationship between two substance types.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
192. Extension.extension:moiety.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`moiety`
194. Extension.extension:moiety.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
196. Extension.extension:characterization
Slice Name	characterization
Definition	This cross-version extension represents SubstanceDefinition.characterization from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General specifications for this substance
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
198. Extension.extension:characterization.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
200. Extension.extension:characterization.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
202. Extension.extension:characterization.extension:technique
Slice Name	technique
Definition	The method used to elucidate the characterization of the drug substance. Example: HPLC.
Short	The method used to find the characterization e.g. HPLC
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
204. Extension.extension:characterization.extension:technique.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
206. Extension.extension:characterization.extension:technique.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
208. Extension.extension:characterization.extension:technique.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`technique`
210. Extension.extension:characterization.extension:technique.value[x]
Definition	The method used to elucidate the characterization of the drug substance. Example: HPLC.
Short	The method used to find the characterization e.g. HPLC
Control	0..1
Binding	For example codes, see R5_substance_structure_technique_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-structure-technique-for-R4\|0.0.1-snapshot-2`) The method used to elucidate the characterization of the drug substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
212. Extension.extension:characterization.extension:form
Slice Name	form
Definition	This cross-version extension represents SubstanceDefinition.characterization.form from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt form
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
214. Extension.extension:characterization.extension:form.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
216. Extension.extension:characterization.extension:form.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
218. Extension.extension:characterization.extension:form.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`form`
220. Extension.extension:characterization.extension:form.value[x]
Definition	This cross-version extension represents SubstanceDefinition.characterization.form from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt form
Control	0..1
Binding	For example codes, see R5_substance_form_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-form-for-R4\|0.0.1-snapshot-2`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
222. Extension.extension:characterization.extension:description
Slice Name	description
Definition	This cross-version extension represents SubstanceDefinition.characterization.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The description or justification in support of the interpretation of the data file
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
224. Extension.extension:characterization.extension:description.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
226. Extension.extension:characterization.extension:description.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
228. Extension.extension:characterization.extension:description.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`description`
230. Extension.extension:characterization.extension:description.value[x]
Definition	This cross-version extension represents SubstanceDefinition.characterization.description from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The description or justification in support of the interpretation of the data file
Control	0..1
Type	markdown
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
232. Extension.extension:characterization.extension:file
Slice Name	file
Definition	This cross-version extension represents SubstanceDefinition.characterization.file from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysis
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
234. Extension.extension:characterization.extension:file.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
236. Extension.extension:characterization.extension:file.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
238. Extension.extension:characterization.extension:file.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`file`
240. Extension.extension:characterization.extension:file.value[x]
Definition	This cross-version extension represents SubstanceDefinition.characterization.file from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysis
Control	0..1
Type	Attachment
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
242. Extension.extension:characterization.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`characterization`
244. Extension.extension:characterization.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
246. Extension.extension:property
Slice Name	property
Definition	This cross-version extension represents SubstanceDefinition.property from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General specifications for this substance
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
248. Extension.extension:property.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
250. Extension.extension:property.extension
Definition	An Extension
Short	Extension
Control	1..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
252. Extension.extension:property.extension:type
Slice Name	type
Definition	This cross-version extension represents SubstanceDefinition.property.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A code expressing the type of property
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
254. Extension.extension:property.extension:type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
256. Extension.extension:property.extension:type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
258. Extension.extension:property.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
260. Extension.extension:property.extension:type.value[x]
Definition	This cross-version extension represents SubstanceDefinition.property.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A code expressing the type of property
Control	0..1
Binding	For example codes, see R5_product_characteristic_codes_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-product-characteristic-codes-for-R4\|0.0.1-snapshot-2`) This value set includes all observable entity codes from SNOMED CT - provided as an exemplar value set.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
262. Extension.extension:property.extension:value[x]
Slice Name	value[x]
Definition	This cross-version extension represents SubstanceDefinition.property.value[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A value for the property
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
264. Extension.extension:property.extension:value[x].id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
266. Extension.extension:property.extension:value[x].extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
268. Extension.extension:property.extension:value[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`value[x]`
270. Extension.extension:property.extension:value[x].value[x]
Definition	This cross-version extension represents SubstanceDefinition.property.value[x] from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A value for the property
Control	0..1
Type	Choice of: CodeableConcept, Quantity, date, boolean, Attachment
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
272. Extension.extension:property.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`property`
274. Extension.extension:property.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
276. Extension.extension:referenceInformation
Slice Name	referenceInformation
Definition	This cross-version extension represents SubstanceDefinition.referenceInformation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General information detailing this substance
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
278. Extension.extension:referenceInformation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
280. Extension.extension:referenceInformation.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
282. Extension.extension:referenceInformation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`referenceInformation`
284. Extension.extension:referenceInformation.value[x]
Definition	This cross-version extension represents SubstanceDefinition.referenceInformation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	General information detailing this substance
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
286. Extension.extension:molecularWeight
Slice Name	molecularWeight
Definition	The average mass of a molecule of a compound compared to 1/12 the mass of carbon 12 and calculated as the sum of the atomic weights of the constituent atoms.
Short	The average mass of a molecule of a compound
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
288. Extension.extension:molecularWeight.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
290. Extension.extension:molecularWeight.extension
Definition	An Extension
Short	Extension
Control	1..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
292. Extension.extension:molecularWeight.extension:method
Slice Name	method
Definition	The method by which the molecular weight was determined.
Short	The method by which the weight was determined
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
294. Extension.extension:molecularWeight.extension:method.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
296. Extension.extension:molecularWeight.extension:method.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
298. Extension.extension:molecularWeight.extension:method.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`method`
300. Extension.extension:molecularWeight.extension:method.value[x]
Definition	The method by which the molecular weight was determined.
Short	The method by which the weight was determined
Control	0..1
Binding	For example codes, see R5_substance_weight_method_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-weight-method-for-R4\|0.0.1-snapshot-2`) The method by which the substance weight was measured.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
302. Extension.extension:molecularWeight.extension:type
Slice Name	type
Definition	Type of molecular weight such as exact, average (also known as. number average), weight average.
Short	Type of molecular weight e.g. exact, average, weight average
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
304. Extension.extension:molecularWeight.extension:type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
306. Extension.extension:molecularWeight.extension:type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
308. Extension.extension:molecularWeight.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
310. Extension.extension:molecularWeight.extension:type.value[x]
Definition	Type of molecular weight such as exact, average (also known as. number average), weight average.
Short	Type of molecular weight e.g. exact, average, weight average
Control	0..1
Binding	For example codes, see R5_substance_weight_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-weight-type-for-R4\|0.0.1-snapshot-2`) The type of substance weight measurement.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
312. Extension.extension:molecularWeight.extension:amount
Slice Name	amount
Definition	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field.
Short	Used to capture quantitative values for a variety of elements
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
314. Extension.extension:molecularWeight.extension:amount.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
316. Extension.extension:molecularWeight.extension:amount.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
318. Extension.extension:molecularWeight.extension:amount.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`amount`
320. Extension.extension:molecularWeight.extension:amount.value[x]
Definition	Used to capture quantitative values for a variety of elements. If only limits are given, the arithmetic mean would be the average. If only a single definite value for a given element is given, it would be captured in this field.
Short	Used to capture quantitative values for a variety of elements
Control	0..1
Type	Quantity
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
322. Extension.extension:molecularWeight.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularWeight`
324. Extension.extension:molecularWeight.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
326. Extension.extension:structure
Slice Name	structure
Definition	This cross-version extension represents SubstanceDefinition.structure from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Structural information
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
328. Extension.extension:structure.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
330. Extension.extension:structure.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
332. Extension.extension:structure.extension:stereochemistry
Slice Name	stereochemistry
Definition	This cross-version extension represents SubstanceDefinition.structure.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry type
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
334. Extension.extension:structure.extension:stereochemistry.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
336. Extension.extension:structure.extension:stereochemistry.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
338. Extension.extension:structure.extension:stereochemistry.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`stereochemistry`
340. Extension.extension:structure.extension:stereochemistry.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.stereochemistry from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Stereochemistry type
Control	0..1
Binding	For example codes, see R5_substance_stereochemistry_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-stereochemistry-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
342. Extension.extension:structure.extension:opticalActivity
Slice Name	opticalActivity
Definition	This cross-version extension represents SubstanceDefinition.structure.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity type
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
344. Extension.extension:structure.extension:opticalActivity.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
346. Extension.extension:structure.extension:opticalActivity.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
348. Extension.extension:structure.extension:opticalActivity.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`opticalActivity`
350. Extension.extension:structure.extension:opticalActivity.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.opticalActivity from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Optical activity type
Control	0..1
Binding	For example codes, see R5_substance_optical_activity_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-optical-activity-for-R4\|0.0.1-snapshot-2`) The optical rotation type of a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
352. Extension.extension:structure.extension:molecularFormula
Slice Name	molecularFormula
Definition	This cross-version extension represents SubstanceDefinition.structure.molecularFormula from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An expression which states the number and type of atoms present in a molecule of a substance
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
354. Extension.extension:structure.extension:molecularFormula.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
356. Extension.extension:structure.extension:molecularFormula.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
358. Extension.extension:structure.extension:molecularFormula.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularFormula`
360. Extension.extension:structure.extension:molecularFormula.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.molecularFormula from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An expression which states the number and type of atoms present in a molecule of a substance
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
362. Extension.extension:structure.extension:molecularFormulaByMoiety
Slice Name	molecularFormulaByMoiety
Definition	Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical, each moiety separated by a dot.
Short	Specified per moiety according to the Hill system
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
364. Extension.extension:structure.extension:molecularFormulaByMoiety.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
366. Extension.extension:structure.extension:molecularFormulaByMoiety.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
368. Extension.extension:structure.extension:molecularFormulaByMoiety.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularFormulaByMoiety`
370. Extension.extension:structure.extension:molecularFormulaByMoiety.value[x]
Definition	Specified per moiety according to the Hill system, i.e. first C, then H, then alphabetical, each moiety separated by a dot.
Short	Specified per moiety according to the Hill system
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
372. Extension.extension:structure.extension:molecularWeight
Slice Name	molecularWeight
Definition	The molecular weight or weight range (for proteins, polymers or nucleic acids).
Short	The molecular weight or weight range
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
374. Extension.extension:structure.extension:molecularWeight.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
376. Extension.extension:structure.extension:molecularWeight.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
378. Extension.extension:structure.extension:molecularWeight.extension:_datatype
Slice Name	_datatype
Definition	Data type name for SubstanceDefinition.structure.molecularWeight from FHIR R5
Short	Data type name for SubstanceDefinition.structure.molecularWeight from FHIR R5
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
380. Extension.extension:structure.extension:molecularWeight.extension:_datatype.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
382. Extension.extension:structure.extension:molecularWeight.extension:_datatype.extension
Definition	An Extension
Short	Extension
Control	0..0
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
384. Extension.extension:structure.extension:molecularWeight.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
386. Extension.extension:structure.extension:molecularWeight.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: SubstanceDefinition.molecularWeight
Control	1..1 This element is affected by the following invariants: ext-1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`SubstanceDefinition.molecularWeight`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
388. Extension.extension:structure.extension:molecularWeight.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`molecularWeight`
390. Extension.extension:structure.extension:molecularWeight.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
392. Extension.extension:structure.extension:technique
Slice Name	technique
Definition	The method used to elucidate the structure of the drug substance. Examples: X-ray, NMR, Peptide mapping, Ligand binding assay.
Short	The method used to find the structure e.g. X-ray, NMR
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
394. Extension.extension:structure.extension:technique.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
396. Extension.extension:structure.extension:technique.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
398. Extension.extension:structure.extension:technique.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`technique`
400. Extension.extension:structure.extension:technique.value[x]
Definition	The method used to elucidate the structure of the drug substance. Examples: X-ray, NMR, Peptide mapping, Ligand binding assay.
Short	The method used to find the structure e.g. X-ray, NMR
Control	0..1
Binding	For example codes, see R5_substance_structure_technique_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-structure-technique-for-R4\|0.0.1-snapshot-2`) The method used to elucidate the structure of the drug substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
402. Extension.extension:structure.extension:sourceDocument
Slice Name	sourceDocument
Definition	The source of information about the structure.
Short	Source of information for the structure
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
404. Extension.extension:structure.extension:sourceDocument.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
406. Extension.extension:structure.extension:sourceDocument.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
408. Extension.extension:structure.extension:sourceDocument.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`sourceDocument`
410. Extension.extension:structure.extension:sourceDocument.value[x]
Definition	The source of information about the structure.
Short	Source of information for the structure
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
412. Extension.extension:structure.extension:representation
Slice Name	representation
Definition	This cross-version extension represents SubstanceDefinition.structure.representation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A depiction of the structure of the substance
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
414. Extension.extension:structure.extension:representation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
416. Extension.extension:structure.extension:representation.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
418. Extension.extension:structure.extension:representation.extension:type
Slice Name	type
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The kind of structural representation (e.g. full, partial)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
420. Extension.extension:structure.extension:representation.extension:type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
422. Extension.extension:structure.extension:representation.extension:type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
424. Extension.extension:structure.extension:representation.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
426. Extension.extension:structure.extension:representation.extension:type.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.type from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The kind of structural representation (e.g. full, partial)
Control	0..1
Binding	For example codes, see R5_substance_representation_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-representation-type-for-R4\|0.0.1-snapshot-2`) A format of a substance representation.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
428. Extension.extension:structure.extension:representation.extension:representation
Slice Name	representation
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.representation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The structural representation as a text string in a standard format
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
430. Extension.extension:structure.extension:representation.extension:representation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
432. Extension.extension:structure.extension:representation.extension:representation.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
434. Extension.extension:structure.extension:representation.extension:representation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`representation`
436. Extension.extension:structure.extension:representation.extension:representation.value[x]
Definition	This cross-version extension represents SubstanceDefinition.structure.representation.representation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The structural representation as a text string in a standard format
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
438. Extension.extension:structure.extension:representation.extension:format
Slice Name	format
Definition	The format of the representation e.g. InChI, SMILES, MOLFILE, CDX, SDF, PDB, mmCIF. The logical content type rather than the physical file format of a document.
Short	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
440. Extension.extension:structure.extension:representation.extension:format.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
442. Extension.extension:structure.extension:representation.extension:format.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
444. Extension.extension:structure.extension:representation.extension:format.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`format`
446. Extension.extension:structure.extension:representation.extension:format.value[x]
Definition	The format of the representation e.g. InChI, SMILES, MOLFILE, CDX, SDF, PDB, mmCIF. The logical content type rather than the physical file format of a document.
Short	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format)
Control	0..1
Binding	For example codes, see R5_substance_representation_format_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-representation-format-for-R4\|0.0.1-snapshot-2`) A format of a substance representation.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
448. Extension.extension:structure.extension:representation.extension:document
Slice Name	document
Definition	An attached file with the structural representation e.g. a molecular structure graphic of the substance, a JCAMP or AnIML file.
Short	An attachment with the structural representation e.g. a structure graphic or AnIML file
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
450. Extension.extension:structure.extension:representation.extension:document.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
452. Extension.extension:structure.extension:representation.extension:document.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
454. Extension.extension:structure.extension:representation.extension:document.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`document`
456. Extension.extension:structure.extension:representation.extension:document.value[x]
Definition	An attached file with the structural representation e.g. a molecular structure graphic of the substance, a JCAMP or AnIML file.
Short	An attachment with the structural representation e.g. a structure graphic or AnIML file
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
458. Extension.extension:structure.extension:representation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`representation`
460. Extension.extension:structure.extension:representation.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
462. Extension.extension:structure.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`structure`
464. Extension.extension:structure.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
466. Extension.extension:name
Slice Name	name
Definition	This cross-version extension represents SubstanceDefinition.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Names applicable to this substance
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
468. Extension.extension:name.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
470. Extension.extension:name.extension
Definition	An Extension
Short	Extension
Control	1..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
472. Extension.extension:name.extension:name
Slice Name	name
Definition	This cross-version extension represents SubstanceDefinition.name.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The actual name
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
474. Extension.extension:name.extension:name.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
476. Extension.extension:name.extension:name.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
478. Extension.extension:name.extension:name.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`name`
480. Extension.extension:name.extension:name.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.name from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The actual name
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
482. Extension.extension:name.extension:type
Slice Name	type
Definition	Name type, for example 'systematic', 'scientific, 'brand'.
Short	Name type e.g. 'systematic', 'scientific, 'brand'
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
484. Extension.extension:name.extension:type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
486. Extension.extension:name.extension:type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
488. Extension.extension:name.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
490. Extension.extension:name.extension:type.value[x]
Definition	Name type, for example 'systematic', 'scientific, 'brand'.
Short	Name type e.g. 'systematic', 'scientific, 'brand'
Control	0..1
Binding	For example codes, see R5_substance_name_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-name-type-for-R4\|0.0.1-snapshot-2`) The type of a name given to a substance.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
492. Extension.extension:name.extension:status
Slice Name	status
Definition	The status of the name, for example 'current', 'proposed'.
Short	The status of the name e.g. 'current', 'proposed'
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
494. Extension.extension:name.extension:status.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
496. Extension.extension:name.extension:status.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
498. Extension.extension:name.extension:status.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`status`
500. Extension.extension:name.extension:status.value[x]
Definition	The status of the name, for example 'current', 'proposed'.
Short	The status of the name e.g. 'current', 'proposed'
Control	0..1
Binding	The codes SHOULD be taken from R5_publication_status_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-publication-status-for-R4\|0.0.1-snapshot-2`) The lifecycle status of an artifact.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
502. Extension.extension:name.extension:preferred
Slice Name	preferred
Definition	This cross-version extension represents SubstanceDefinition.name.preferred from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If this is the preferred name for this substance
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
504. Extension.extension:name.extension:preferred.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
506. Extension.extension:name.extension:preferred.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
508. Extension.extension:name.extension:preferred.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`preferred`
510. Extension.extension:name.extension:preferred.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.preferred from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	If this is the preferred name for this substance
Control	0..1
Type	boolean
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
512. Extension.extension:name.extension:language
Slice Name	language
Definition	This cross-version extension represents SubstanceDefinition.name.language from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Human language that the name is written in
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
514. Extension.extension:name.extension:language.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
516. Extension.extension:name.extension:language.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
518. Extension.extension:name.extension:language.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`language`
520. Extension.extension:name.extension:language.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.language from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Human language that the name is written in
Control	0..1
Binding	The codes SHALL be taken from AllLanguages (required to `http://hl7.org/fhir/ValueSet/all-languages\|4.0.1`) IETF language tag for a human language
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
522. Extension.extension:name.extension:domain
Slice Name	domain
Definition	The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive.
Short	The use context of this name e.g. as an active ingredient or as a food colour additive
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
524. Extension.extension:name.extension:domain.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
526. Extension.extension:name.extension:domain.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
528. Extension.extension:name.extension:domain.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`domain`
530. Extension.extension:name.extension:domain.value[x]
Definition	The use context of this name for example if there is a different name a drug active ingredient as opposed to a food colour additive.
Short	The use context of this name e.g. as an active ingredient or as a food colour additive
Control	0..1
Binding	For example codes, see R5_substance_name_domain_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-name-domain-for-R4\|0.0.1-snapshot-2`) The use context of a substance name for example if there is a different name when used as a drug active ingredient as opposed to a food colour additive.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
532. Extension.extension:name.extension:jurisdiction
Slice Name	jurisdiction
Definition	This cross-version extension represents SubstanceDefinition.name.jurisdiction from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The jurisdiction where this name applies
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
534. Extension.extension:name.extension:jurisdiction.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
536. Extension.extension:name.extension:jurisdiction.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
538. Extension.extension:name.extension:jurisdiction.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`jurisdiction`
540. Extension.extension:name.extension:jurisdiction.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.jurisdiction from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The jurisdiction where this name applies
Control	0..1
Binding	For example codes, see R5_jurisdiction_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-jurisdiction-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
542. Extension.extension:name.extension:synonym
Slice Name	synonym
Definition	This cross-version extension represents SubstanceDefinition.name.synonym from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A synonym of this particular name, by which the substance is also known
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
544. Extension.extension:name.extension:synonym.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
546. Extension.extension:name.extension:synonym.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
548. Extension.extension:name.extension:synonym.extension:_datatype
Slice Name	_datatype
Definition	Data type name for SubstanceDefinition.name.synonym from FHIR R5
Short	Data type name for SubstanceDefinition.name.synonym from FHIR R5
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
550. Extension.extension:name.extension:synonym.extension:_datatype.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
552. Extension.extension:name.extension:synonym.extension:_datatype.extension
Definition	An Extension
Short	Extension
Control	0..0
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
554. Extension.extension:name.extension:synonym.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
556. Extension.extension:name.extension:synonym.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: SubstanceDefinition.name
Control	1..1 This element is affected by the following invariants: ext-1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`SubstanceDefinition.name`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
558. Extension.extension:name.extension:synonym.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`synonym`
560. Extension.extension:name.extension:synonym.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
562. Extension.extension:name.extension:translation
Slice Name	translation
Definition	This cross-version extension represents SubstanceDefinition.name.translation from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	A translation for this name into another human language
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
564. Extension.extension:name.extension:translation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
566. Extension.extension:name.extension:translation.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
568. Extension.extension:name.extension:translation.extension:_datatype
Slice Name	_datatype
Definition	Data type name for SubstanceDefinition.name.translation from FHIR R5
Short	Data type name for SubstanceDefinition.name.translation from FHIR R5
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
570. Extension.extension:name.extension:translation.extension:_datatype.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
572. Extension.extension:name.extension:translation.extension:_datatype.extension
Definition	An Extension
Short	Extension
Control	0..0
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
574. Extension.extension:name.extension:translation.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
576. Extension.extension:name.extension:translation.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: SubstanceDefinition.name
Control	1..1 This element is affected by the following invariants: ext-1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`SubstanceDefinition.name`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
578. Extension.extension:name.extension:translation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`translation`
580. Extension.extension:name.extension:translation.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
582. Extension.extension:name.extension:official
Slice Name	official
Definition	This cross-version extension represents SubstanceDefinition.name.official from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Details of the official nature of this name
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
584. Extension.extension:name.extension:official.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
586. Extension.extension:name.extension:official.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
588. Extension.extension:name.extension:official.extension:authority
Slice Name	authority
Definition	This cross-version extension represents SubstanceDefinition.name.official.authority from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Which authority uses this official name
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
590. Extension.extension:name.extension:official.extension:authority.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
592. Extension.extension:name.extension:official.extension:authority.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
594. Extension.extension:name.extension:official.extension:authority.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`authority`
596. Extension.extension:name.extension:official.extension:authority.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.official.authority from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Which authority uses this official name
Control	0..1
Binding	The codes SHOULD be taken from R5_substance_name_authority_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-name-authority-for-R4\|0.0.1-snapshot-2`) An authority that officates substance names.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
598. Extension.extension:name.extension:official.extension:status
Slice Name	status
Definition	The status of the official name, for example 'draft', 'active', 'retired'.
Short	The status of the official name, for example 'draft', 'active'
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
600. Extension.extension:name.extension:official.extension:status.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
602. Extension.extension:name.extension:official.extension:status.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
604. Extension.extension:name.extension:official.extension:status.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`status`
606. Extension.extension:name.extension:official.extension:status.value[x]
Definition	The status of the official name, for example 'draft', 'active', 'retired'.
Short	The status of the official name, for example 'draft', 'active'
Control	0..1
Binding	The codes SHOULD be taken from R5_publication_status_for_R4 (0.0.1-snapshot-2) (preferred to `http://hl7.org/fhir/5.0/ValueSet/R5-publication-status-for-R4\|0.0.1-snapshot-2`) The lifecycle status of an artifact.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
608. Extension.extension:name.extension:official.extension:date
Slice Name	date
Definition	Date of the official name change.
Short	Date of official name change
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
610. Extension.extension:name.extension:official.extension:date.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
612. Extension.extension:name.extension:official.extension:date.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
614. Extension.extension:name.extension:official.extension:date.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`date`
616. Extension.extension:name.extension:official.extension:date.value[x]
Definition	Date of the official name change.
Short	Date of official name change
Control	0..1
Type	dateTime
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
618. Extension.extension:name.extension:official.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`official`
620. Extension.extension:name.extension:official.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
622. Extension.extension:name.extension:source
Slice Name	source
Definition	This cross-version extension represents SubstanceDefinition.name.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
624. Extension.extension:name.extension:source.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
626. Extension.extension:name.extension:source.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
628. Extension.extension:name.extension:source.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`source`
630. Extension.extension:name.extension:source.value[x]
Definition	This cross-version extension represents SubstanceDefinition.name.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
632. Extension.extension:name.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`name`
634. Extension.extension:name.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
636. Extension.extension:relationship
Slice Name	relationship
Definition	A link between this substance and another, with details of the relationship.
Short	A link between this substance and another
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
638. Extension.extension:relationship.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
640. Extension.extension:relationship.extension
Definition	An Extension
Short	Extension
Control	1..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
642. Extension.extension:relationship.extension:substanceDefinition[x]
Slice Name	substanceDefinition[x]
Definition	A pointer to another substance, as a resource or just a representational code.
Short	A pointer to another substance, as a resource or a representational code
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
644. Extension.extension:relationship.extension:substanceDefinition[x].id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
646. Extension.extension:relationship.extension:substanceDefinition[x].extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
648. Extension.extension:relationship.extension:substanceDefinition[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`substanceDefinition[x]`
650. Extension.extension:relationship.extension:substanceDefinition[x].value[x]
Definition	A pointer to another substance, as a resource or just a representational code.
Short	A pointer to another substance, as a resource or a representational code
Control	0..1
Type	Choice of: Reference, CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
652. Extension.extension:relationship.extension:type
Slice Name	type
Definition	For example "salt to parent", "active moiety", "starting material", "polymorph", "impurity of".
Short	For example "salt to parent", "active moiety"
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
654. Extension.extension:relationship.extension:type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
656. Extension.extension:relationship.extension:type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
658. Extension.extension:relationship.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
660. Extension.extension:relationship.extension:type.value[x]
Definition	For example "salt to parent", "active moiety", "starting material", "polymorph", "impurity of".
Short	For example "salt to parent", "active moiety"
Control	0..1
Binding	For example codes, see R5_substance_relationship_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-relationship-type-for-R4\|0.0.1-snapshot-2`) The relationship between two substance types.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
662. Extension.extension:relationship.extension:isDefining
Slice Name	isDefining
Definition	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible substance relationships.
Short	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationships
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
664. Extension.extension:relationship.extension:isDefining.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
666. Extension.extension:relationship.extension:isDefining.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
668. Extension.extension:relationship.extension:isDefining.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`isDefining`
670. Extension.extension:relationship.extension:isDefining.value[x]
Definition	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible substance relationships.
Short	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationships
Control	0..1
Type	boolean
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
672. Extension.extension:relationship.extension:amount[x]
Slice Name	amount[x]
Definition	A numeric factor for the relationship, for instance to express that the salt of a substance has some percentage of the active substance in relation to some other.
Short	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some other
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
674. Extension.extension:relationship.extension:amount[x].id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
676. Extension.extension:relationship.extension:amount[x].extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
678. Extension.extension:relationship.extension:amount[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`amount[x]`
680. Extension.extension:relationship.extension:amount[x].value[x]
Definition	A numeric factor for the relationship, for instance to express that the salt of a substance has some percentage of the active substance in relation to some other.
Short	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some other
Control	0..1
Type	Choice of: Quantity, Ratio, string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
682. Extension.extension:relationship.extension:ratioHighLimitAmount
Slice Name	ratioHighLimitAmount
Definition	This cross-version extension represents SubstanceDefinition.relationship.ratioHighLimitAmount from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	For use when the numeric has an uncertain range
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
684. Extension.extension:relationship.extension:ratioHighLimitAmount.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
686. Extension.extension:relationship.extension:ratioHighLimitAmount.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
688. Extension.extension:relationship.extension:ratioHighLimitAmount.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`ratioHighLimitAmount`
690. Extension.extension:relationship.extension:ratioHighLimitAmount.value[x]
Definition	This cross-version extension represents SubstanceDefinition.relationship.ratioHighLimitAmount from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	For use when the numeric has an uncertain range
Control	0..1
Type	Ratio
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
692. Extension.extension:relationship.extension:comparator
Slice Name	comparator
Definition	This cross-version extension represents SubstanceDefinition.relationship.comparator from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An operator for the amount, for example "average", "approximately", "less than"
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
694. Extension.extension:relationship.extension:comparator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
696. Extension.extension:relationship.extension:comparator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
698. Extension.extension:relationship.extension:comparator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`comparator`
700. Extension.extension:relationship.extension:comparator.value[x]
Definition	This cross-version extension represents SubstanceDefinition.relationship.comparator from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An operator for the amount, for example "average", "approximately", "less than"
Control	0..1
Binding	For example codes, see R5_substance_amount_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-amount-type-for-R4\|0.0.1-snapshot-2`) The relationship between two substance types.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
702. Extension.extension:relationship.extension:source
Slice Name	source
Definition	This cross-version extension represents SubstanceDefinition.relationship.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
704. Extension.extension:relationship.extension:source.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
706. Extension.extension:relationship.extension:source.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
708. Extension.extension:relationship.extension:source.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`source`
710. Extension.extension:relationship.extension:source.value[x]
Definition	This cross-version extension represents SubstanceDefinition.relationship.source from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Supporting literature
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
712. Extension.extension:relationship.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`relationship`
714. Extension.extension:relationship.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
716. Extension.extension:nucleicAcid
Slice Name	nucleicAcid
Definition	This cross-version extension represents SubstanceDefinition.nucleicAcid from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to nucleic acids
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
718. Extension.extension:nucleicAcid.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
720. Extension.extension:nucleicAcid.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
722. Extension.extension:nucleicAcid.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`nucleicAcid`
724. Extension.extension:nucleicAcid.value[x]
Definition	This cross-version extension represents SubstanceDefinition.nucleicAcid from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to nucleic acids
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
726. Extension.extension:polymer
Slice Name	polymer
Definition	This cross-version extension represents SubstanceDefinition.polymer from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to polymers
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
728. Extension.extension:polymer.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
730. Extension.extension:polymer.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
732. Extension.extension:polymer.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`polymer`
734. Extension.extension:polymer.value[x]
Definition	This cross-version extension represents SubstanceDefinition.polymer from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to polymers
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
736. Extension.extension:protein
Slice Name	protein
Definition	This cross-version extension represents SubstanceDefinition.protein from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to proteins
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
738. Extension.extension:protein.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
740. Extension.extension:protein.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
742. Extension.extension:protein.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`protein`
744. Extension.extension:protein.value[x]
Definition	This cross-version extension represents SubstanceDefinition.protein from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	Data items specific to proteins
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
746. Extension.extension:sourceMaterial
Slice Name	sourceMaterial
Definition	Material or taxonomic/anatomical source for the substance.
Short	Material or taxonomic/anatomical source
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
748. Extension.extension:sourceMaterial.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
750. Extension.extension:sourceMaterial.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
752. Extension.extension:sourceMaterial.extension:type
Slice Name	type
Definition	A classification that provides the origin of the raw material. Example: cat hair would be an Animal source type.
Short	Classification of the origin of the raw material. e.g. cat hair is an Animal source type
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
754. Extension.extension:sourceMaterial.extension:type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
756. Extension.extension:sourceMaterial.extension:type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
758. Extension.extension:sourceMaterial.extension:type.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`type`
760. Extension.extension:sourceMaterial.extension:type.value[x]
Definition	A classification that provides the origin of the raw material. Example: cat hair would be an Animal source type.
Short	Classification of the origin of the raw material. e.g. cat hair is an Animal source type
Control	0..1
Binding	For example codes, see R5_substance_source_material_type_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-type-for-R4\|0.0.1-snapshot-2`) A classification that provides the origin of the substance raw material.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
762. Extension.extension:sourceMaterial.extension:genus
Slice Name	genus
Definition	The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
Short	The genus of an organism e.g. the Latin epithet of the plant/animal scientific name
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
764. Extension.extension:sourceMaterial.extension:genus.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
766. Extension.extension:sourceMaterial.extension:genus.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
768. Extension.extension:sourceMaterial.extension:genus.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`genus`
770. Extension.extension:sourceMaterial.extension:genus.value[x]
Definition	The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
Short	The genus of an organism e.g. the Latin epithet of the plant/animal scientific name
Control	0..1
Binding	For example codes, see R5_substance_source_material_genus_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-genus-for-R4\|0.0.1-snapshot-2`) The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
772. Extension.extension:sourceMaterial.extension:species
Slice Name	species
Definition	The species of an organism, typically referring to the Latin epithet of the species of the plant/animal.
Short	The species of an organism e.g. the Latin epithet of the species of the plant/animal
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
774. Extension.extension:sourceMaterial.extension:species.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
776. Extension.extension:sourceMaterial.extension:species.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
778. Extension.extension:sourceMaterial.extension:species.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`species`
780. Extension.extension:sourceMaterial.extension:species.value[x]
Definition	The species of an organism, typically referring to the Latin epithet of the species of the plant/animal.
Short	The species of an organism e.g. the Latin epithet of the species of the plant/animal
Control	0..1
Binding	For example codes, see R5_substance_source_material_species_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-species-for-R4\|0.0.1-snapshot-2`) A species of origin a substance raw material.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
782. Extension.extension:sourceMaterial.extension:part
Slice Name	part
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.part from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An anatomical origin of the source material within an organism
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
784. Extension.extension:sourceMaterial.extension:part.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
786. Extension.extension:sourceMaterial.extension:part.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
788. Extension.extension:sourceMaterial.extension:part.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`part`
790. Extension.extension:sourceMaterial.extension:part.value[x]
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.part from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	An anatomical origin of the source material within an organism
Control	0..1
Binding	For example codes, see R5_substance_source_material_part_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/5.0/ValueSet/R5-substance-source-material-part-for-R4\|0.0.1-snapshot-2`) An anatomical origin of the source material within an organism.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
792. Extension.extension:sourceMaterial.extension:countryOfOrigin
Slice Name	countryOfOrigin
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.countryOfOrigin from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The country or countries where the material is harvested
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
794. Extension.extension:sourceMaterial.extension:countryOfOrigin.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
796. Extension.extension:sourceMaterial.extension:countryOfOrigin.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
798. Extension.extension:sourceMaterial.extension:countryOfOrigin.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`countryOfOrigin`
800. Extension.extension:sourceMaterial.extension:countryOfOrigin.value[x]
Definition	This cross-version extension represents SubstanceDefinition.sourceMaterial.countryOfOrigin from http://hl7.org/fhir/StructureDefinition/SubstanceDefinition\|5.0.0 for use in FHIR R4.
Short	The country or countries where the material is harvested
Control	0..1
Binding	The codes SHALL be taken from R5_country_for_R4 (0.0.1-snapshot-2) (required to `http://hl7.org/fhir/5.0/ValueSet/R5-country-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
802. Extension.extension:sourceMaterial.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`sourceMaterial`
804. Extension.extension:sourceMaterial.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
806. Extension.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/5.0/StructureDefinition/extension-SubstanceDefinition`
808. Extension.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)