Generated Narrative: StructureDefinition profile-AdverseEvent Name Flags Card. Type Description & Constraints AdverseEvent 0..* AdverseEvent Medical care, research study or other healthcare event causing physical injury #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:encounter 0..1 Reference(Cross-version Profile for R5.Encounter for use in FHIR STU3(0.1.0) | Encounter) R5: The Encounter associated with the start of the AdverseEvent (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.encounter #xD; extension:occurrence 0..1 Period, Timing R5: When the event occurred additional types URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.occurrence #xD; extension:detected 0..1 dateTime R5: When the event was detected (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.detected #xD; extension:recordedDate 0..1 dateTime R5: When the event was recorded (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.recordedDate #xD; extension:participant 0..* (Complex) R5: Who was involved in the adverse event or the potential adverse event and what they did (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.participant #xD; extension:expectedInResearchStudy 0..1 boolean R5: Considered likely or probable or anticipated in the research study (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.expectedInResearchStudy #xD; extension:contributingFactor 0..* (Complex) R5: Contributing factors suspected to have increased the probability or severity of the adverse event (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.contributingFactor #xD; extension:preventiveAction 0..* (Complex) R5: Preventive actions that contributed to avoiding the adverse event (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.preventiveAction #xD; extension:mitigatingAction 0..* (Complex) R5: Ameliorating actions taken after the adverse event occured in order to reduce the extent of harm (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.mitigatingAction #xD; extension:supportingInfo 0..* (Complex) R5: Supporting information relevant to the event (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.supportingInfo #xD; extension:note 0..* Annotation R5: Comment on adverse event (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.note #xD; Slices for modifierExtension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; modifierExtension:status 1..1 code R5: in-progress | completed | entered-in-error | unknown (new) URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.status Binding: R5AdverseEventStatusForR3 (0.1.0) (required): Codes identifying the lifecycle stage of an event. #xD; category #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:category 0..* CodeableConcept R5: wrong-patient | procedure-mishap | medication-mishap | device | unsafe-physical-environment | hospital-aquired-infection | wrong-body-site additional types URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.category Binding: R5AdverseEventCategoryForR3 (0.1.0) (example): Overall categorization of the event, e.g. product-related or situational. #xD; type #xD; Slices for modifierExtension 0..* Slice: Unordered, Open by value:url #xD; modifierExtension:actuality 1..1 code R5: actuality URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.actuality Binding: R5AdverseEventActualityForR3 (0.1.0) (required): Overall nature of the adverse event, e.g. real or potential. #xD; subject #xD; Slices for extension 1..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:subject 1..1 ?gen-e1? [CanonicalType[http://hl7.org/fhir/StructureDefinition/alternate-reference]] R5: Subject impacted by event URL: http://hl7.org/fhir/StructureDefinition/alternate-reference #xD; reaction #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:resultingEffect 0..* ?gen-e1? [CanonicalType[http://hl7.org/fhir/StructureDefinition/alternate-reference]] R5: Effect on the subject due to this event additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference #xD; location #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:location 0..1 ?gen-e1? [CanonicalType[http://hl7.org/fhir/StructureDefinition/alternate-reference]] R5: location additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference #xD; recorder #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:recorder 0..1 ?gen-e1? [CanonicalType[http://hl7.org/fhir/StructureDefinition/alternate-reference]] R5: recorder URL: http://hl7.org/fhir/StructureDefinition/alternate-reference #xD; suspectEntity #xD; instance #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:instance 0..1 CodeableConcept R5: instance additional types URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.suspectEntity.instance #xD; extension:instanceAlternateReference 0..1 ?gen-e1? [CanonicalType[http://hl7.org/fhir/StructureDefinition/alternate-reference]] R5: instance additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference #xD; causalityProductRelatedness #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:entityRelatedness 0..1 CodeableConcept R5: Result of the assessment regarding the relatedness of the suspected entity to the event additional types URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-AdverseEvent.suspectEntity.causality.entityRelatedness Binding: AdverseEventCausalityAssessment (example): Codes for the assessment of whether the entity caused the event. #xD; causalityAuthor #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:author 0..1 ?gen-e1? [CanonicalType[http://hl7.org/fhir/StructureDefinition/alternate-reference]] R5: Author of the information on the possible cause of the event URL: http://hl7.org/fhir/StructureDefinition/alternate-reference #xD; study #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Open by value:url #xD; extension:study 0..* ?gen-e1? [CanonicalType[http://hl7.org/fhir/StructureDefinition/alternate-reference]] R5: Research study that the subject is enrolled in additional types URL: http://hl7.org/fhir/StructureDefinition/alternate-reference #xD; Documentation for this format
Cross-version Profile for R5.AdverseEvent for use in FHIR STU3
This cross-version profile allows R5 AdverseEvent content to be represented via FHIR STU3 AdverseEvent resources.
Medical care, research study or other healthcare event causing physical injury
Actual or potential/avoided event causing unintended physical injury resulting from or contributed to by medical care, a research study or other healthcare setting factors that requires additional monitoring, treatment, or hospitalization, or that results in death.
If the resource is contained in another resource, it SHALL NOT contain nested Resources
not(parent::f:contained and f:contained)
If the resource is contained in another resource, it SHALL NOT contain any narrative
If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated
contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))
If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource
contained.where(('#'+id in %resource.descendants().reference).not()).empty()
not(exists(for $id in f:contained/*/@id return $id[not(ancestor::f:contained/parent::*/descendant::f:reference/@value=concat('#', $id))]))
The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.
The only time that a resource does not have an id is when it is being submitted to the server using a create operation.
The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content may not always be associated with version changes to the resource.
A set of rules under which this content was created
A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content.
Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. This element is labelled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation.
The base language in which the resource is written.
Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).
Text summary of the resource, for human interpretation
A human-readable narrative that contains a summary of the resource, and may be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.
Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded in formation is added later.
These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.
This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again.
R5: The Encounter associated with the start of the AdverseEvent (new)
R5: `AdverseEvent.encounter` (new:Reference(Encounter))
Element `AdverseEvent.encounter` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.encounter` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element). This will typically be the encounter the event occurred within, but some activities may be initiated prior to or after the official completion of an encounter but still be tied to the context of the encounter. For example, if a medication administration was considered an adverse event because it resulted in a rash, then the encounter when the medication administration was given is the associated encounter. If the patient reports the AdverseEvent during a second encounter, that second encounter is not the associated encounter.
All FHIR elements must have a @value or children
hasValue() | (children().count() > id.count())
Must have either extensions or value[x], not both
exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])
R5: When the event occurred additional types
R5: `AdverseEvent.occurrence[x]` additional types (Period, Timing)
Element `AdverseEvent.occurrence[x]` is mapped to FHIR STU3 element `AdverseEvent.date` as `SourceIsBroaderThanTarget`. The mappings for `AdverseEvent.occurrence[x]` do not cover the following types: Period, Timing.
R5: `AdverseEvent.detected` (new:dateTime)
Element `AdverseEvent.detected` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.detected` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element).
R5: `AdverseEvent.recordedDate` (new:dateTime)
Element `AdverseEvent.recordedDate` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.recordedDate` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element). The recordedDate represents the date when this particular AdverseEvent record was created in the system, not the date of the most recent update. The date of the last record modification can be retrieved from the resource metadata.
R5: Who was involved in the adverse event or the potential adverse event and what they did (new)
R5: `AdverseEvent.participant` (new:BackboneElement)
Element `AdverseEvent.participant` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.participant` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element).
R5: Considered likely or probable or anticipated in the research study (new)
R5: `AdverseEvent.expectedInResearchStudy` (new:boolean)
Element `AdverseEvent.expectedInResearchStudy` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.expectedInResearchStudy` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element).
R5: Contributing factors suspected to have increased the probability or severity of the adverse event (new)
R5: `AdverseEvent.contributingFactor` (new:BackboneElement)
Element `AdverseEvent.contributingFactor` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.contributingFactor` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element).
R5: Preventive actions that contributed to avoiding the adverse event (new)
R5: `AdverseEvent.preventiveAction` (new:BackboneElement)
Element `AdverseEvent.preventiveAction` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.preventiveAction` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element).
R5: Ameliorating actions taken after the adverse event occured in order to reduce the extent of harm (new)
R5: `AdverseEvent.mitigatingAction` (new:BackboneElement)
Element `AdverseEvent.mitigatingAction` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.mitigatingAction` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element).
R5: Supporting information relevant to the event (new)
R5: `AdverseEvent.supportingInfo` (new:BackboneElement)
Element `AdverseEvent.supportingInfo` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.supportingInfo` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element).
R5: `AdverseEvent.note` (new:Annotation)
Element `AdverseEvent.note` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.note` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element).
R5: in-progress | completed | entered-in-error | unknown (new)
Element `AdverseEvent.status` has a context of AdverseEvent based on following the parent source element upwards and mapping to `AdverseEvent`. Element `AdverseEvent.status` has no mapping targets in FHIR STU3. Typically, this is because the element has been added (is a new element). This is not the reporting of the event to any regulatory or quality organization. This is not the outcome of the patient's condition.
The identifier(s) of this adverse event that are assigned by business processes and/or used to refer to it when a direct URL reference to the resource itsefl is not appropriate.
AE | PAE An adverse event is an event that caused harm to a patient, an adverse reaction is a something that is a subject-specific event that is a result of an exposure to a medication, food, device or environmental substance, a potential adverse event is something that occurred and that could have caused harm to a patient but did not
The type of event which is important to characterize what occurred and caused harm to the subject, or had the potential to cause harm to the subject.
Overall categorization of the event, e.g. real or potential
unique id for the element within a resource (for internal references)
R5: wrong-patient | procedure-mishap | medication-mishap | device | unsafe-physical-environment | hospital-aquired-infection | wrong-body-site additional types
R5: `AdverseEvent.category` additional types (CodeableConcept) additional types from child elements (coding)
Element `AdverseEvent.category` is mapped to FHIR STU3 element `AdverseEvent.category` as `RelatedTo`. The mappings for `AdverseEvent.category` do not cover the following types: CodeableConcept. The mappings for `AdverseEvent.category` do not cover the following types based on type expansion: coding.
This element defines the specific type of event that occurred or that was prevented from occurring.
unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Extensions are always sliced by (at least) url
Additional Content defined by implementations
May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
A reference to a code defined by a terminology system.
Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Allows for translations and alternate encodings within a code system. Also supports communication of the same instance to systems requiring different encodings.
fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding
Plain text representation of the concept
A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Very often the text is the same as a displayName of one of the codings.
The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
C*E.9. But note many systems use C*E.2 for this
fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText
This subject or group impacted by the event. With a prospective adverse event, there will be no subject as the adverse event was prevented.
Element `AdverseEvent.subject` is mapped to FHIR STU3 element `AdverseEvent.subject` as `SourceIsBroaderThanTarget`. The standard extension `alternate-reference` has been mapped as the representation of FHIR R5 element `AdverseEvent.subject` with unmapped reference targets: Group, Patient, Practitioner, RelatedPerson, ResearchSubject. If AdverseEvent.resultingEffect differs among members of the group, then use Patient as the subject.
Literal reference, Relative, internal or absolute URL
A reference to a location at which the other resource is found. The reference may be a relative reference, in which case it is relative to the service base URL, or an absolute URL that resolves to the location where the resource is found. The reference may be version specific or not. If the reference is not to a FHIR RESTful server, then it should be assumed to be version specific. Internal fragment references (start with '#') refer to contained resources.
Using absolute URLs provides a stable scalable approach suitable for a cloud/web context, while using relative/logical references provides a flexible approach suitable for use when trading across closed eco-system boundaries. Absolute URLs do not need to point to a FHIR RESTful server, though this is the preferred approach. If the URL conforms to the structure "/[type]/[id]" then it should be assumed that the reference is to a FHIR RESTful server.
Logical reference, when literal reference is not known
An identifier for the other resource. This is used when there is no way to reference the other resource directly, either because the entity is not available through a FHIR server, or because there is no way for the author of the resource to convert a known identifier to an actual location. There is no requirement that a Reference.identifier point to something that is actually exposed as a FHIR instance, but it SHALL point to a business concept that would be expected to be exposed as a FHIR instance, and that instance would need to be of a FHIR resource type allowed by the reference.
When an identifier is provided in place of a reference, any system processing the reference will only be able to resolve the identifier to a reference if it understands the business context in which the identifier is used. Sometimes this is global (e.g. a national identifier) but often it is not. For this reason, none of the useful mechanisms described for working with references (e.g. chaining, includes) are possible, nor should servers be expected to be able resolve the reference. Servers may accept an identifier based reference untouched, resolve it, and/or reject it - see CapabilityStatement.rest.resource.referencePolicy. When both an identifier and a literal reference are provided, the literal reference is preferred. Applications processing the resource are allowed - but not required - to check that the identifier matches the literal reference Applications converting a logical reference to a literal reference may choose to leave the logical reference present, or remove it.
Plain text narrative that identifies the resource in addition to the resource reference.
This is generally not the same as the Resource.text of the referenced resource. The purpose is to identify what's being referenced, not to fully describe it.
The date (and perhaps time) when the adverse event occurred.
Adverse Reaction Events linked to exposure to substance
Includes information about the reaction that occurred as a result of exposure to a substance (for example, a drug or a chemical).
R5: Effect on the subject due to this event additional types
R5: `AdverseEvent.resultingEffect` additional types from child elements (display, identifier, reference, type)
Element `AdverseEvent.resultingEffect` is mapped to FHIR STU3 element `AdverseEvent.reaction` as `SourceIsBroaderThanTarget`. The mappings for `AdverseEvent.resultingEffect` do not cover the following types based on type expansion: display, identifier, reference, type. The standard extension `alternate-reference` has been mapped as the representation of FHIR R5 element `AdverseEvent.resultingEffect` with unmapped reference targets: Condition, Observation.
The information about where the adverse event occurred.
R5: `AdverseEvent.location` additional types from child elements (display, identifier, reference, type)
Element `AdverseEvent.location` is mapped to FHIR STU3 element `AdverseEvent.location` as `SourceIsBroaderThanTarget`. The mappings for `AdverseEvent.location` do not cover the following types based on type expansion: display, identifier, reference, type. The standard extension `alternate-reference` has been mapped as the representation of FHIR R5 element `AdverseEvent.location` with unmapped reference targets: Location.
Describes the seriousness or severity of the adverse event.
Overall seriousness of this event for the patient
resolved | recovering | ongoing | resolvedWithSequelae | fatal | unknown
Describes the type of outcome from the adverse event.
Information on who recorded the adverse event. May be the patient or a practitioner.
Element `AdverseEvent.recorder` is mapped to FHIR STU3 element `AdverseEvent.recorder` as `SourceIsBroaderThanTarget`. The standard extension `alternate-reference` has been mapped as the representation of FHIR R5 element `AdverseEvent.recorder` with unmapped reference targets: Patient, Practitioner, PractitionerRole, RelatedPerson, ResearchSubject.
Who was involved in the adverse event or the potential adverse event
Parties that may or should contribute or have contributed information to the Act. Such information includes information leading to the decision to perform the Act and how to perform the Act (e.g. consultant), information that the Act itself seeks to reveal (e.g. informant of clinical history), or information about what Act was performed (e.g. informant witness).
The suspected agent causing the adverse event
Describes the entity that is suspected to have caused the adverse event.
May be used to represent additional information that is not part of the basic definition of the element, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.
Refers to the specific entity that caused the adverse event
Identifies the actual instance of what caused the adverse event. May be a substance, medication, medication administration, medication statement or a device.
R5: `AdverseEvent.suspectEntity.instance[x]` additional types (CodeableConcept)
Element `AdverseEvent.suspectEntity.instance[x]` is mapped to FHIR STU3 element `AdverseEvent.suspectEntity.instance` as `SourceIsBroaderThanTarget`. The mappings for `AdverseEvent.suspectEntity.instance[x]` do not cover the following types: CodeableConcept. The standard extension `alternate-reference` has been mapped as PART of the representation of FHIR R5 element `AdverseEvent.suspectEntity.instance[x]` with unmapped reference targets: BiologicallyDerivedProduct, Device, Immunization, Medication, MedicationAdministration, MedicationStatement, Procedure, ResearchStudy, Substance.
R5: Result of the assessment regarding the relatedness of the suspected entity to the event additional types
R5: `AdverseEvent.suspectEntity.causality.entityRelatedness` additional types (CodeableConcept) additional types from child elements (coding)
Element `AdverseEvent.suspectEntity.causality.entityRelatedness` is mapped to FHIR STU3 element `AdverseEvent.suspectEntity.causalityProductRelatedness` as `SourceIsBroaderThanTarget`. The mappings for `AdverseEvent.suspectEntity.causality.entityRelatedness` do not cover the following types: CodeableConcept. The mappings for `AdverseEvent.suspectEntity.causality.entityRelatedness` do not cover the following types based on type expansion: coding.
R5: Author of the information on the possible cause of the event
R5: `AdverseEvent.suspectEntity.causality.author`
Element `AdverseEvent.suspectEntity.causality.author` is mapped to FHIR STU3 element `AdverseEvent.suspectEntity.causalityAuthor` as `SourceIsBroaderThanTarget`. The standard extension `alternate-reference` has been mapped as the representation of FHIR R5 element `AdverseEvent.suspectEntity.causality.author` with unmapped reference targets: Patient, Practitioner, PractitionerRole, RelatedPerson, ResearchSubject.
R5: Research study that the subject is enrolled in additional types
R5: `AdverseEvent.study` additional types from child elements (display, identifier, reference, type)
Element `AdverseEvent.study` is mapped to FHIR STU3 element `AdverseEvent.study` as `SourceIsBroaderThanTarget`. The mappings for `AdverseEvent.study` do not cover the following types based on type expansion: display, identifier, reference, type. The standard extension `alternate-reference` has been mapped as the representation of FHIR R5 element `AdverseEvent.study` with unmapped reference targets: ResearchStudy.
Element `AdverseEvent.actuality` is mapped to FHIR STU3 element `AdverseEvent.type` as `SourceIsNarrowerThanTarget`. AllergyIntolerance should be used for the initial capture or recording of the individual's propensity to an adverse reaction to a substance. If an AllergyIntolerance does not exist, then an adverse reaction should be recorded as an AllergyIntolerance. If an AllergyIntolerance does exist and the substance was given, then an adverse reaction should be recorded as an AdverseEvent due to the aberrant workflow.